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GSE58827: Dynamics of the Mouse Liver

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Results for Zfhx3

Z-value: 0.60

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Transcription factors associated with Zfhx3

Gene Symbol Gene ID Gene Info
Zfhx3
ENSMUSG00000038872.8 zinc finger homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfhx3mm10_v2_chr8_+_108714644_108714644-0.163.5e-01Click!

Activity profile of Zfhx3 motif

Sorted Z-values of Zfhx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_27000362 4.87 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr1_+_174172738 4.62 ENSMUST00000027817.7
Spta1
spectrin alpha, erythrocytic 1
chr15_-_79285502 3.88 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chrX_-_162964557 3.66 ENSMUST00000038769.2
S100g
S100 calcium binding protein G
chr19_+_10015016 3.39 ENSMUST00000137637.1
ENSMUST00000149967.1
Rab3il1
RAB3A interacting protein (rabin3)-like 1
chr1_-_132390301 3.21 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr15_-_79285470 2.61 ENSMUST00000170955.1
Baiap2l2
BAI1-associated protein 2-like 2
chr11_+_24078111 2.59 ENSMUST00000109516.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr11_+_24078022 2.43 ENSMUST00000000881.6
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr1_-_89933290 2.36 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr7_-_4397705 2.30 ENSMUST00000108590.2
Gp6
glycoprotein 6 (platelet)
chr5_-_43981757 2.26 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr3_+_153844209 2.24 ENSMUST00000044089.3
Asb17
ankyrin repeat and SOCS box-containing 17
chr10_+_79927330 2.16 ENSMUST00000105376.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr10_+_79927039 2.11 ENSMUST00000019708.5
ENSMUST00000105377.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr11_+_24078173 2.00 ENSMUST00000109514.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr6_+_142298419 1.85 ENSMUST00000041993.2
Iapp
islet amyloid polypeptide
chr17_-_43502773 1.70 ENSMUST00000024707.8
ENSMUST00000117137.1
Mep1a
meprin 1 alpha
chrX_+_164140447 1.66 ENSMUST00000073973.4
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr8_-_107065632 1.61 ENSMUST00000034393.5
Tmed6
transmembrane emp24 protein transport domain containing 6
chrX_-_139871637 1.52 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4
microrchidia 4
chr1_-_126830632 1.45 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5
NCK-associated protein 5
chr11_+_3983704 1.39 ENSMUST00000063004.7
Gal3st1
galactose-3-O-sulfotransferase 1
chr7_+_30493622 1.33 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
Prodh2
proline dehydrogenase (oxidase) 2
chr11_+_3983636 1.32 ENSMUST00000078757.1
Gal3st1
galactose-3-O-sulfotransferase 1
chr19_-_38043559 1.31 ENSMUST00000041475.8
ENSMUST00000172095.2
Myof
myoferlin
chr18_+_11633276 1.31 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr6_-_141773810 1.23 ENSMUST00000148411.1
Gm5724
predicted gene 5724
chr2_-_121235689 1.20 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr18_+_37518341 1.19 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr11_-_76027726 1.18 ENSMUST00000021207.6
Fam101b
family with sequence similarity 101, member B
chr4_+_13743424 1.16 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_4880669 1.06 ENSMUST00000078030.3
Gm6104
predicted gene 6104
chr3_-_17230976 1.04 ENSMUST00000177874.1
Gm5283
predicted gene 5283
chr2_+_121506748 1.00 ENSMUST00000099473.3
ENSMUST00000110602.2
Wdr76
WD repeat domain 76
chr9_-_120068263 0.90 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1
chemokine (C-X3-C) receptor 1
chr3_-_75270073 0.89 ENSMUST00000039047.4
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr5_+_25246775 0.87 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr19_-_31765027 0.85 ENSMUST00000065067.6
Prkg1
protein kinase, cGMP-dependent, type I
chrX_+_163911401 0.85 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr10_-_30842765 0.81 ENSMUST00000019924.8
Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr13_-_58354862 0.80 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr13_-_95478655 0.80 ENSMUST00000022186.3
S100z
S100 calcium binding protein, zeta
chr1_-_66945361 0.79 ENSMUST00000160100.1
Myl1
myosin, light polypeptide 1
chr2_-_140671462 0.76 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr3_+_136670076 0.74 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr17_-_24073479 0.73 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr8_+_93810832 0.71 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1
guanine nucleotide binding protein, alpha O
chr10_-_44458687 0.66 ENSMUST00000105490.2
Prdm1
PR domain containing 1, with ZNF domain
chr12_-_87443800 0.66 ENSMUST00000162961.1
Alkbh1
alkB, alkylation repair homolog 1 (E. coli)
chr1_-_172895048 0.65 ENSMUST00000027824.5
Apcs
serum amyloid P-component
chr16_-_74411776 0.65 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr1_-_138175126 0.65 ENSMUST00000183301.1
Ptprc
protein tyrosine phosphatase, receptor type, C
chr11_-_79530569 0.64 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
Evi2a
Evi2b
ecotropic viral integration site 2a
ecotropic viral integration site 2b
chr4_+_150920154 0.60 ENSMUST00000105672.3
ENSMUST00000030808.3
Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
chr3_-_130730375 0.60 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr17_-_50094277 0.58 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr4_-_32923455 0.56 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6
ankyrin repeat domain 6
chr4_+_101507947 0.56 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr2_-_140671400 0.54 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr2_-_165368723 0.51 ENSMUST00000141140.1
ENSMUST00000103085.1
Zfp663
zinc finger protein 663
chr6_+_52177498 0.51 ENSMUST00000070587.3
5730596B20Rik
RIKEN cDNA 5730596B20 gene
chr9_+_95857597 0.50 ENSMUST00000034980.7
Atr
ataxia telangiectasia and Rad3 related
chr8_+_83666827 0.49 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr1_-_138175283 0.48 ENSMUST00000182755.1
ENSMUST00000183262.1
ENSMUST00000027645.7
ENSMUST00000112036.2
ENSMUST00000182283.1
Ptprc
protein tyrosine phosphatase, receptor type, C
chr6_-_122340499 0.47 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr3_-_59220150 0.46 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr1_-_138175238 0.45 ENSMUST00000182536.1
Ptprc
protein tyrosine phosphatase, receptor type, C
chr3_+_28263205 0.43 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr11_+_4986824 0.43 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1
adaptor protein complex AP-1, beta 1 subunit
chr15_+_102459193 0.39 ENSMUST00000164957.1
ENSMUST00000171245.1
Prr13
proline rich 13
chr10_-_88605017 0.38 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1
myosin binding protein C, slow-type
chr7_+_103928825 0.38 ENSMUST00000106863.1
Olfr631
olfactory receptor 631
chr12_+_71170589 0.36 ENSMUST00000129376.1
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr10_+_23796946 0.35 ENSMUST00000119597.1
ENSMUST00000179321.1
Slc18b1
solute carrier family 18, subfamily B, member 1
chr15_+_102459028 0.35 ENSMUST00000164938.1
ENSMUST00000023810.5
Prr13
proline rich 13
chr3_+_84952146 0.35 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr9_+_53771499 0.35 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chrX_+_164373363 0.35 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr1_-_126830786 0.33 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr10_-_44458715 0.33 ENSMUST00000039174.4
Prdm1
PR domain containing 1, with ZNF domain
chrX_+_112011007 0.33 ENSMUST00000131304.1
Tex16
testis expressed gene 16
chr10_-_130394241 0.33 ENSMUST00000094502.4
Vmn2r84
vomeronasal 2, receptor 84
chr4_+_82065924 0.32 ENSMUST00000161588.1
Gm5860
predicted gene 5860
chr7_+_55794146 0.32 ENSMUST00000032627.3
Tubgcp5
tubulin, gamma complex associated protein 5
chr5_+_107497762 0.31 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr4_+_109343029 0.31 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr3_-_72967854 0.31 ENSMUST00000167334.1
Sis
sucrase isomaltase (alpha-glucosidase)
chr3_-_69859875 0.31 ENSMUST00000051239.7
ENSMUST00000171529.1
Sptssb
serine palmitoyltransferase, small subunit B
chr17_-_40880525 0.30 ENSMUST00000068258.2
9130008F23Rik
RIKEN cDNA 9130008F23 gene
chr11_+_89073841 0.28 ENSMUST00000100619.4
Gm525
predicted gene 525
chr2_+_70039114 0.28 ENSMUST00000060208.4
Myo3b
myosin IIIB
chr3_-_145032765 0.28 ENSMUST00000029919.5
Clca3
chloride channel calcium activated 3
chr12_-_54695885 0.28 ENSMUST00000067272.8
Eapp
E2F-associated phosphoprotein
chr15_+_91231578 0.28 ENSMUST00000109284.2
CN725425
cDNA sequence CN725425
chr18_+_55057557 0.28 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr13_-_75943812 0.28 ENSMUST00000022078.5
ENSMUST00000109606.1
Rhobtb3
Rho-related BTB domain containing 3
chr1_-_136006342 0.23 ENSMUST00000166193.2
Igfn1
immunoglobulin-like and fibronectin type III domain containing 1
chr9_+_36832684 0.23 ENSMUST00000034630.8
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr3_+_76075583 0.20 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr12_-_27160498 0.19 ENSMUST00000182592.1
Gm9866
predicted gene 9866
chr9_+_113812547 0.19 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2
CLIP associating protein 2
chr5_+_107497718 0.17 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr18_+_73863672 0.17 ENSMUST00000134847.1
Mro
maestro
chr8_-_66486494 0.17 ENSMUST00000026681.5
Tma16
translation machinery associated 16 homolog (S. cerevisiae)
chr9_+_85312773 0.15 ENSMUST00000113205.1
Gm11114
predicted gene 11114
chr7_+_19119853 0.15 ENSMUST00000053109.3
Fbxo46
F-box protein 46
chr12_-_27160311 0.14 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866
predicted gene 9866
chr12_-_12941827 0.14 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_+_78051220 0.12 ENSMUST00000144728.1
4930440I19Rik
RIKEN cDNA 4930440I19 gene
chr18_+_32815383 0.12 ENSMUST00000025237.3
Tslp
thymic stromal lymphopoietin
chr1_-_158814469 0.11 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr10_+_23797052 0.10 ENSMUST00000133289.1
Slc18b1
solute carrier family 18, subfamily B, member 1
chr6_-_38124568 0.10 ENSMUST00000040259.4
Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr2_-_72986716 0.10 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chrX_+_71972986 0.09 ENSMUST00000066116.1
Fate1
fetal and adult testis expressed 1
chrX_+_112240474 0.09 ENSMUST00000164272.2
ENSMUST00000132037.1
4933403O08Rik
RIKEN cDNA 4933403O08 gene
chr7_-_100583072 0.08 ENSMUST00000152876.1
ENSMUST00000150042.1
Mrpl48
mitochondrial ribosomal protein L48
chr6_+_127453667 0.08 ENSMUST00000112193.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr15_-_55548164 0.07 ENSMUST00000165356.1
Mrpl13
mitochondrial ribosomal protein L13
chr2_+_88817173 0.07 ENSMUST00000072057.1
Olfr1202
olfactory receptor 1202
chr9_-_48964990 0.07 ENSMUST00000008734.4
Htr3b
5-hydroxytryptamine (serotonin) receptor 3B
chr2_-_140671440 0.07 ENSMUST00000099301.1
Flrt3
fibronectin leucine rich transmembrane protein 3
chr16_-_79091078 0.06 ENSMUST00000023566.4
ENSMUST00000060402.5
Tmprss15
transmembrane protease, serine 15
chr3_+_125404072 0.06 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr8_+_72107040 0.06 ENSMUST00000055735.4
Olfr374
olfactory receptor 374
chr12_-_54695829 0.04 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
Eapp
E2F-associated phosphoprotein
chr5_+_24394388 0.04 ENSMUST00000115074.1
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr1_+_125676969 0.04 ENSMUST00000027581.6
Gpr39
G protein-coupled receptor 39
chrX_+_112311334 0.03 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool
apolipoprotein O-like
chr19_-_31764963 0.03 ENSMUST00000182685.1
Prkg1
protein kinase, cGMP-dependent, type I
chr5_-_86468990 0.03 ENSMUST00000101073.2
Tmprss11a
transmembrane protease, serine 11a
chr1_+_179961110 0.03 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa
CDC42 binding protein kinase alpha
chr6_-_86765807 0.02 ENSMUST00000123732.1
Anxa4
annexin A4
chr17_+_35076902 0.00 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr6_-_86765866 0.00 ENSMUST00000113675.1
Anxa4
annexin A4

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfhx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.0 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.5 4.9 GO:0030916 otic vesicle formation(GO:0030916)
0.5 1.4 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.4 1.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.4 1.7 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.3 1.0 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.3 1.6 GO:2000473 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.3 2.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 2.4 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.3 2.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.3 6.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 0.8 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3 1.3 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2 0.7 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.2 1.9 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.7 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.2 0.7 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 0.9 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2 0.5 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2 0.7 GO:0002101 tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.2 0.5 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 0.8 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.6 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.9 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 2.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 4.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.6 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 1.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 3.2 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.3 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 1.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.3 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.8 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.0 GO:0035483 gastric emptying(GO:0035483)
0.0 0.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 1.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.6 GO:0032437 cuticular plate(GO:0032437)
0.5 6.5 GO:0071439 clathrin complex(GO:0071439)
0.2 2.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 0.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.2 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 8.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 6.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.9 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.5 3.7 GO:0005499 vitamin D binding(GO:0005499)
0.3 0.8 GO:0035939 microsatellite binding(GO:0035939)
0.2 1.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 1.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 2.3 GO:0038064 collagen receptor activity(GO:0038064)
0.2 0.9 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.7 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.7 GO:0051430 G-protein coupled serotonin receptor binding(GO:0031821) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.5 GO:0032407 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 2.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 3.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 12.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 2.4 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162) microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 1.3 GO:0008565 protein transporter activity(GO:0008565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 5.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 4.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation