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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for GAUCAGA

Z-value: 0.33

Motif logo

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miRNA associated with seed GAUCAGA

NamemiRBASE accession
mmu-miR-383-5p.1
MIMAT0000748

Activity profile of GAUCAGA motif

Sorted Z-values of GAUCAGA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102658640 0.67 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr3_+_63295815 0.65 ENSMUST00000029400.1
Mme
membrane metallo endopeptidase
chr17_-_12507704 0.24 ENSMUST00000024595.2
Slc22a3
solute carrier family 22 (organic cation transporter), member 3
chr15_+_54571358 0.23 ENSMUST00000025356.2
Mal2
mal, T cell differentiation protein 2
chr15_+_100304782 0.21 ENSMUST00000067752.3
Mettl7a1
methyltransferase like 7A1
chr6_-_71440623 0.19 ENSMUST00000002292.8
Rmnd5a
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_+_8948608 0.16 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr1_-_177796451 0.14 ENSMUST00000016105.8
Adss
adenylosuccinate synthetase, non muscle
chr6_+_146724957 0.13 ENSMUST00000001675.7
ENSMUST00000111644.1
Stk38l
serine/threonine kinase 38 like
chr2_-_80581234 0.12 ENSMUST00000028386.5
Nckap1
NCK-associated protein 1
chr19_-_34879452 0.12 ENSMUST00000036584.5
Pank1
pantothenate kinase 1
chr4_-_22488296 0.10 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr5_-_5514730 0.10 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12
claudin 12
chr19_-_29648355 0.10 ENSMUST00000159692.1
Ermp1
endoplasmic reticulum metallopeptidase 1
chr8_-_85299483 0.09 ENSMUST00000034131.8
Vps35
vacuolar protein sorting 35
chr13_+_96542727 0.09 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr2_+_126034647 0.09 ENSMUST00000064794.7
Fgf7
fibroblast growth factor 7
chrX_-_64276937 0.09 ENSMUST00000114679.1
ENSMUST00000069926.7
Slitrk4
SLIT and NTRK-like family, member 4
chr10_-_127522428 0.09 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr7_+_110018301 0.08 ENSMUST00000084731.3
Ipo7
importin 7
chr2_-_105904484 0.08 ENSMUST00000122965.1
Elp4
elongation protein 4 homolog (S. cerevisiae)
chr19_+_8617991 0.08 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr9_+_54286479 0.08 ENSMUST00000056740.5
Gldn
gliomedin
chr13_-_111490111 0.08 ENSMUST00000047627.7
Gpbp1
GC-rich promoter binding protein 1
chr9_+_101074727 0.08 ENSMUST00000085177.3
Msl2
male-specific lethal 2 homolog (Drosophila)
chr14_-_46788267 0.08 ENSMUST00000015903.4
Cnih1
cornichon homolog 1 (Drosophila)
chr8_+_88199194 0.07 ENSMUST00000119033.1
ENSMUST00000066748.3
ENSMUST00000118952.1
Papd5
PAP associated domain containing 5
chr6_+_30401866 0.07 ENSMUST00000068240.6
ENSMUST00000068259.6
Klhdc10
kelch domain containing 10
chr6_-_35539765 0.07 ENSMUST00000031866.5
Mtpn
myotrophin
chr10_+_106470281 0.07 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr15_-_37007382 0.07 ENSMUST00000078976.7
Zfp706
zinc finger protein 706
chr1_+_55131231 0.07 ENSMUST00000162364.1
ENSMUST00000159311.1
Mob4
MOB family member 4, phocein
chr7_+_97579868 0.06 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1
remodeling and spacing factor 1
chr14_+_48446340 0.06 ENSMUST00000111735.2
Tmem260
transmembrane protein 260
chr9_+_40269430 0.06 ENSMUST00000171835.2
Scn3b
sodium channel, voltage-gated, type III, beta
chr10_+_76531593 0.06 ENSMUST00000048678.6
Lss
lanosterol synthase
chr18_+_20510291 0.06 ENSMUST00000070892.6
Dsg3
desmoglein 3
chr9_+_44604844 0.06 ENSMUST00000170489.1
Ddx6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chrX_-_102644210 0.05 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
Phka1
phosphorylase kinase alpha 1
chrX_+_75416628 0.05 ENSMUST00000033544.7
Brcc3
BRCA1/BRCA2-containing complex, subunit 3
chr9_-_43105718 0.04 ENSMUST00000165665.1
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chrX_+_134601179 0.04 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
chr13_+_8202860 0.04 ENSMUST00000064473.6
Adarb2
adenosine deaminase, RNA-specific, B2
chr2_+_155775333 0.04 ENSMUST00000029141.5
Mmp24
matrix metallopeptidase 24
chr14_-_55660397 0.04 ENSMUST00000002400.6
Mdp1
magnesium-dependent phosphatase 1
chr15_-_98534221 0.04 ENSMUST00000116400.2
ENSMUST00000023727.10
Kansl2
KAT8 regulatory NSL complex subunit 2
chr13_+_55593135 0.04 ENSMUST00000109905.3
Tmed9
transmembrane emp24 protein transport domain containing 9
chr3_-_144570136 0.03 ENSMUST00000043325.7
Hs2st1
heparan sulfate 2-O-sulfotransferase 1
chr7_+_43579577 0.03 ENSMUST00000058104.7
Zfp719
zinc finger protein 719
chr12_-_51691883 0.03 ENSMUST00000013130.8
ENSMUST00000169503.1
Strn3
striatin, calmodulin binding protein 3
chr19_-_60874526 0.03 ENSMUST00000025961.6
Prdx3
peroxiredoxin 3
chr3_+_132684106 0.03 ENSMUST00000169172.1
ENSMUST00000029664.6
Tbck
TBC1 domain containing kinase
chr5_+_125532377 0.03 ENSMUST00000031446.6
Tmem132b
transmembrane protein 132B
chr17_-_10319324 0.03 ENSMUST00000097414.3
ENSMUST00000042296.7
Qk
quaking
chr4_-_99829180 0.02 ENSMUST00000146258.1
Itgb3bp
integrin beta 3 binding protein (beta3-endonexin)
chr4_-_126256226 0.02 ENSMUST00000122129.1
ENSMUST00000061143.8
ENSMUST00000106132.2
Map7d1
MAP7 domain containing 1
chr13_-_98891036 0.02 ENSMUST00000109399.2
Tnpo1
transportin 1
chr18_+_73573044 0.02 ENSMUST00000091852.4
Mex3c
mex3 homolog C (C. elegans)
chr16_-_85173692 0.02 ENSMUST00000005406.10
App
amyloid beta (A4) precursor protein
chr11_+_53770014 0.02 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1
interferon regulatory factor 1
chr8_-_122974793 0.02 ENSMUST00000098334.5
Ankrd11
ankyrin repeat domain 11
chr6_-_72439549 0.01 ENSMUST00000059472.8
Mat2a
methionine adenosyltransferase II, alpha
chr8_-_111338152 0.01 ENSMUST00000056157.7
ENSMUST00000120432.1
Mlkl
mixed lineage kinase domain-like
chr5_-_136615328 0.00 ENSMUST00000053319.2
4731417B20Rik
RIKEN cDNA 4731417B20 gene
chr6_-_99266494 0.00 ENSMUST00000113326.2
Foxp1
forkhead box P1
chr2_-_84650714 0.00 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
Ctnnd1
catenin (cadherin associated protein), delta 1
chr11_-_61579637 0.00 ENSMUST00000147501.1
ENSMUST00000146455.1
ENSMUST00000108711.1
ENSMUST00000108712.1
ENSMUST00000001063.8
ENSMUST00000108713.1
ENSMUST00000179936.1
ENSMUST00000178202.1
Epn2
epsin 2
chr7_-_111082997 0.00 ENSMUST00000161051.1
ENSMUST00000160132.1
ENSMUST00000106666.3
ENSMUST00000162415.1
Eif4g2
eukaryotic translation initiation factor 4, gamma 2
chr11_-_86201144 0.00 ENSMUST00000044423.3
Brip1
BRCA1 interacting protein C-terminal helicase 1
chr11_+_98863610 0.00 ENSMUST00000142414.1
ENSMUST00000037480.8
Wipf2
WAS/WASL interacting protein family, member 2
chr18_-_38284391 0.00 ENSMUST00000025311.5
Pcdh12
protocadherin 12

Network of associatons between targets according to the STRING database.

First level regulatory network of GAUCAGA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.7 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:2000331 positive regulation of Wnt protein secretion(GO:0061357) regulation of terminal button organization(GO:2000331)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.1 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354) mesodermal cell migration(GO:0008078) establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0051608 histamine transport(GO:0051608)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.0 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0005914 spot adherens junction(GO:0005914)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.1 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis