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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for GGCAGUG

Z-value: 0.67

Motif logo

miRNA associated with seed GGCAGUG

NamemiRBASE accession
MIMAT0000542
MIMAT0000382
MIMAT0000381
MIMAT0001542
MIMAT0005447
MIMAT0003460

Activity profile of GGCAGUG motif

Sorted Z-values of GGCAGUG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_86078070 2.91 ENSMUST00000032069.5
adducin 2 (beta)
chr11_-_102088471 1.34 ENSMUST00000017458.4
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr1_-_119422239 1.29 ENSMUST00000038765.5
inhibin beta-B
chr13_+_95696851 1.07 ENSMUST00000022182.4
coagulation factor II (thrombin) receptor-like 2
chr7_+_117380937 1.06 ENSMUST00000032892.5
xylosyltransferase 1
chrX_+_160390684 1.00 ENSMUST00000112408.2
ENSMUST00000112402.1
ENSMUST00000112401.1
ENSMUST00000112400.1
ENSMUST00000112405.2
ENSMUST00000112404.2
ENSMUST00000146805.1
G protein-coupled receptor 64
chr16_-_43979050 0.99 ENSMUST00000165648.1
ENSMUST00000036321.7
zinc finger, DHHC domain containing 23
chrX_-_142306170 0.99 ENSMUST00000134825.2
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr7_+_26061495 0.97 ENSMUST00000005669.7
cytochrome P450, family 2, subfamily b, polypeptide 13
chr19_-_5273080 0.96 ENSMUST00000025786.7
phosphofurin acidic cluster sorting protein 1
chr10_-_62340514 0.95 ENSMUST00000099691.4
hexokinase 1
chr4_-_49597860 0.93 ENSMUST00000042750.2
transmembrane protein 246
chr2_-_157079212 0.87 ENSMUST00000069098.6
suppressor of glucose, autophagy associated 1
chr11_+_82892116 0.87 ENSMUST00000018988.5
fibronectin type III domain containing 8
chr7_+_27258725 0.85 ENSMUST00000079258.6
numb-like
chr2_+_156840077 0.84 ENSMUST00000081335.6
ENSMUST00000073352.3
TGFB-induced factor homeobox 2
chr17_-_81649607 0.83 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_+_91540553 0.82 ENSMUST00000027538.7
ankyrin repeat and SOCS box-containing 1
chr4_-_88033328 0.72 ENSMUST00000078090.5
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_-_68954351 0.72 ENSMUST00000030036.5
bone morphogenic protein/retinoic acid inducible neural specific 1
chr5_-_112392213 0.72 ENSMUST00000031291.7
aspartate beta-hydroxylase domain containing 2
chrX_+_71962971 0.72 ENSMUST00000048790.6
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr4_-_45084538 0.69 ENSMUST00000052236.6
F-box protein 10
chr6_+_42264983 0.68 ENSMUST00000031895.6
caspase 2
chr13_+_54371340 0.66 ENSMUST00000026985.8
complexin 2
chr9_-_53975246 0.63 ENSMUST00000048409.7
ELMO/CED-12 domain containing 1
chr5_+_37050854 0.62 ENSMUST00000043794.4
janus kinase and microtubule interacting protein 1
chr12_-_50649190 0.61 ENSMUST00000002765.7
protein kinase D1
chr13_-_28953690 0.61 ENSMUST00000067230.5
SRY-box containing gene 4
chr5_-_137072254 0.61 ENSMUST00000077523.3
ENSMUST00000041388.4
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr11_+_116198853 0.58 ENSMUST00000021130.6
TEN1 telomerase capping complex subunit
chr3_-_127409044 0.57 ENSMUST00000182704.1
ankyrin 2, brain
chr4_+_11191726 0.57 ENSMUST00000029866.9
ENSMUST00000108324.3
cyclin E2
chr2_+_4400958 0.56 ENSMUST00000075767.7
FERM domain containing 4A
chr11_-_76509419 0.54 ENSMUST00000094012.4
active BCR-related gene
chr2_-_163918683 0.53 ENSMUST00000044734.2
regulating synaptic membrane exocytosis 4
chr5_+_113490447 0.53 ENSMUST00000094452.3
WSC domain containing 2
chr3_+_123446913 0.52 ENSMUST00000029603.8
protease, serine, 12 neurotrypsin (motopsin)
chr17_+_28801090 0.51 ENSMUST00000004985.9
bromodomain and PHD finger containing, 3
chr15_+_103240405 0.50 ENSMUST00000036004.9
ENSMUST00000087351.7
heterogeneous nuclear ribonucleoprotein A1
chr5_-_22344690 0.50 ENSMUST00000062372.7
ENSMUST00000161356.1
reelin
chrX_-_48454152 0.50 ENSMUST00000114958.1
E74-like factor 4 (ets domain transcription factor)
chr9_-_100571049 0.47 ENSMUST00000093792.2
solute carrier family 35, member G2
chr14_-_65425453 0.47 ENSMUST00000059339.5
prepronociceptin
chr17_-_23645264 0.47 ENSMUST00000024696.7
matrix metallopeptidase 25
chr9_+_96196246 0.46 ENSMUST00000165120.2
ENSMUST00000034982.9
transcription factor Dp 2
chr1_+_75382114 0.46 ENSMUST00000113590.1
ENSMUST00000148515.1
SPEG complex locus
chr2_-_34913976 0.46 ENSMUST00000028232.3
PHD finger protein 19
chr1_-_37541003 0.44 ENSMUST00000151952.1
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr7_+_126272589 0.43 ENSMUST00000056028.9
SH3-binding kinase 1
chr15_+_98632220 0.43 ENSMUST00000109150.1
calcium channel, voltage-dependent, beta 3 subunit
chr4_-_136835843 0.43 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Eph receptor B2
chr9_-_85327110 0.43 ENSMUST00000034802.8
family with sequence similarity 46, member A
chr6_+_127887582 0.43 ENSMUST00000032501.4
tetraspanin 11
chr15_-_91573181 0.43 ENSMUST00000109283.1
solute carrier family 2 (facilitated glucose transporter), member 13
chr19_-_6128208 0.42 ENSMUST00000025702.7
sorting nexin 15
chr6_+_4747306 0.42 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
paternally expressed 10
chr13_-_117025505 0.42 ENSMUST00000022239.6
poly (ADP-ribose) polymerase family, member 8
chr1_-_135585314 0.41 ENSMUST00000040599.8
ENSMUST00000067414.6
neuron navigator 1
chr12_-_84876479 0.40 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
latent transforming growth factor beta binding protein 2
chr9_+_109875541 0.40 ENSMUST00000094324.3
cell division cycle 25A
chr2_+_162943474 0.40 ENSMUST00000035751.5
ENSMUST00000156954.1
l(3)mbt-like (Drosophila)
chr2_+_179442427 0.40 ENSMUST00000000314.6
cadherin 4
chr17_-_67354459 0.39 ENSMUST00000037974.8
protein tyrosine phosphatase, receptor type, M
chr7_-_25788635 0.39 ENSMUST00000002677.4
ENSMUST00000085948.4
AXL receptor tyrosine kinase
chr2_+_121289589 0.38 ENSMUST00000094639.3
microtubule-associated protein 1 A
chr10_+_128377086 0.38 ENSMUST00000014642.3
ankyrin repeat domain 52
chr11_+_75650501 0.37 ENSMUST00000102505.3
myosin IC
chr2_-_157007039 0.36 ENSMUST00000103129.2
ENSMUST00000103130.1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr11_-_98053415 0.36 ENSMUST00000017544.2
SH3 and cysteine rich domain 2
chr7_+_139085984 0.36 ENSMUST00000026551.8
dihydropyrimidinase-like 4
chr11_-_106160101 0.36 ENSMUST00000045923.3
LIM domain containing 2
chr3_-_27710413 0.35 ENSMUST00000046157.4
fibronectin type III domain containing 3B
chr6_+_47877204 0.34 ENSMUST00000061890.7
zinc finger protein 282
chr5_-_113908685 0.33 ENSMUST00000004646.6
coronin, actin binding protein 1C
chr11_-_96977660 0.33 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2 transcription factor
chr1_-_133753681 0.33 ENSMUST00000125659.1
ENSMUST00000165602.2
ENSMUST00000048953.7
ATPase, Ca++ transporting, plasma membrane 4
chr9_-_89622986 0.33 ENSMUST00000044491.6
cDNA sequence AF529169
chr11_+_94990996 0.32 ENSMUST00000038696.5
protein phosphatase 1, regulatory subunit 9B
chr12_+_77239036 0.31 ENSMUST00000062804.7
fucosyltransferase 8
chr9_+_21337828 0.31 ENSMUST00000034697.7
solute carrier family 44, member 2
chr14_+_30479565 0.31 ENSMUST00000022535.7
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr17_-_51832666 0.30 ENSMUST00000144331.1
special AT-rich sequence binding protein 1
chr2_+_71117923 0.30 ENSMUST00000028403.2
cytochrome b reductase 1
chr11_+_101176041 0.30 ENSMUST00000103109.3
contactin associated protein-like 1
chr8_-_70439557 0.29 ENSMUST00000076615.5
CREB regulated transcription coactivator 1
chr17_+_84511832 0.29 ENSMUST00000047206.5
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr15_-_97908261 0.29 ENSMUST00000023119.8
vitamin D receptor
chr1_-_119837613 0.28 ENSMUST00000064091.5
protein tyrosine phosphatase, non-receptor type 4
chr5_+_91517615 0.28 ENSMUST00000040576.9
prostate androgen-regulated mucin-like protein 1
chr1_-_36558349 0.28 ENSMUST00000114991.1
ENSMUST00000114992.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr7_+_16401187 0.27 ENSMUST00000098789.3
zinc finger CCCH-type containing 4
chr8_+_124793061 0.27 ENSMUST00000041106.7
tripartite motif-containing 67
chr8_+_116943387 0.27 ENSMUST00000109099.3
ATM interactor
chr11_-_114066174 0.27 ENSMUST00000041627.7
sidekick homolog 2 (chicken)
chr14_-_70159433 0.26 ENSMUST00000058240.7
ENSMUST00000153871.1
RIKEN cDNA 9930012K11 gene
chr10_-_110000219 0.26 ENSMUST00000032719.7
neuron navigator 3
chr6_-_13839916 0.26 ENSMUST00000060442.7
G protein-coupled receptor 85
chr12_-_101819048 0.26 ENSMUST00000021603.8
fibulin 5
chr9_+_108991902 0.25 ENSMUST00000147989.1
ENSMUST00000051873.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr3_+_94478831 0.25 ENSMUST00000029784.5
CUGBP, Elav-like family member 3
chr10_+_85386813 0.24 ENSMUST00000105307.1
ENSMUST00000020231.3
BTB (POZ) domain containing 11
chr8_+_93810832 0.24 ENSMUST00000034198.8
ENSMUST00000125716.1
guanine nucleotide binding protein, alpha O
chr18_+_61105844 0.24 ENSMUST00000115268.3
colony stimulating factor 1 receptor
chr7_+_80186835 0.24 ENSMUST00000107383.1
ENSMUST00000032754.7
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr11_-_98022594 0.23 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
calcium channel, voltage-dependent, beta 1 subunit
chr6_-_101377897 0.23 ENSMUST00000075994.6
PDZ domain containing RING finger 3
chr3_+_90341654 0.23 ENSMUST00000049382.4
GATA zinc finger domain containing 2B
chr7_+_43463145 0.23 ENSMUST00000107977.1
ZV-set and immunoglobulin domain containing 10 like
chr4_-_16013868 0.23 ENSMUST00000037198.3
oxidative stress induced growth inhibitor family member 2
chrX_+_161162744 0.23 ENSMUST00000074802.5
ENSMUST00000019101.4
ENSMUST00000112345.1
sex comb on midleg-like 2 (Drosophila)
chr15_-_98296083 0.22 ENSMUST00000169721.1
ENSMUST00000023722.5
zinc finger protein 641
chr8_+_95703037 0.22 ENSMUST00000073139.7
ENSMUST00000080666.7
N-myc downstream regulated gene 4
chr6_-_118197732 0.22 ENSMUST00000032201.5
ENSMUST00000088790.3
ret proto-oncogene
chr2_+_106693185 0.21 ENSMUST00000111063.1
metallophosphoesterase domain containing 2
chr7_-_126799163 0.21 ENSMUST00000032934.5
aldolase A, fructose-bisphosphate
chr2_-_25983236 0.21 ENSMUST00000114167.2
ENSMUST00000091268.4
ENSMUST00000183461.1
calmodulin regulated spectrin-associated protein 1
chr6_-_31563978 0.21 ENSMUST00000026698.7
podocalyxin-like
chr3_+_131110350 0.21 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
lymphoid enhancer binding factor 1
chr9_+_108986163 0.20 ENSMUST00000052724.3
urocortin 2
chr11_+_105589970 0.20 ENSMUST00000168598.1
ENSMUST00000100330.3
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr2_-_93334467 0.20 ENSMUST00000111265.2
tetraspanin 18
chr17_+_46202740 0.20 ENSMUST00000087031.5
exportin 5
chr19_+_8941865 0.20 ENSMUST00000096240.2
metastasis-associated gene family, member 2
chr1_-_156939626 0.19 ENSMUST00000063199.6
ENSMUST00000027886.7
ENSMUST00000172057.1
Ral GEF with PH domain and SH3 binding motif 2
chr15_-_79546741 0.19 ENSMUST00000054014.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr7_-_98178254 0.19 ENSMUST00000040971.7
calpain 5
chr11_+_106276715 0.19 ENSMUST00000044462.3
testicular cell adhesion molecule 1
chr11_+_61485431 0.19 ENSMUST00000064783.3
ENSMUST00000040522.6
microfibrillar-associated protein 4
chr4_+_58943575 0.18 ENSMUST00000107554.1
zinc finger with KRAB and SCAN domains 16
chr4_+_21931291 0.18 ENSMUST00000029908.7
failed axon connections homolog (Drosophila)
chr8_-_122699066 0.18 ENSMUST00000127984.1
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr1_+_132298606 0.18 ENSMUST00000046071.4
kelch domain containing 8A
chr5_+_75152274 0.18 ENSMUST00000000476.8
platelet derived growth factor receptor, alpha polypeptide
chr9_+_70678950 0.17 ENSMUST00000067880.6
a disintegrin and metallopeptidase domain 10
chr15_-_66969616 0.17 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
N-myc downstream regulated gene 1
chr10_+_126978690 0.17 ENSMUST00000105256.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr18_+_86394952 0.17 ENSMUST00000058829.2
neuropilin (NRP) and tolloid (TLL)-like 1
chr9_+_65908967 0.16 ENSMUST00000034949.3
ENSMUST00000154589.1
casein kinase 1, gamma 1
chr9_-_107635330 0.16 ENSMUST00000055704.6
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr3_-_107518001 0.16 ENSMUST00000169449.1
ENSMUST00000029499.8
solute carrier family 6 (neurotransmitter transporter), member 17
chr14_+_14012491 0.16 ENSMUST00000022257.2
ataxin 7
chr5_+_19907502 0.16 ENSMUST00000101558.3
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_+_59805829 0.16 ENSMUST00000030080.6
sorting nexin family member 30
chr8_-_111933761 0.16 ENSMUST00000034429.7
transmembrane protein 231
chr19_-_5663701 0.16 ENSMUST00000071857.5
ENSMUST00000080824.5
ENSMUST00000164304.1
ENSMUST00000169854.1
signal-induced proliferation associated gene 1
chr2_-_137116624 0.16 ENSMUST00000028735.7
jagged 1
chr1_-_166002591 0.16 ENSMUST00000111429.4
ENSMUST00000176800.1
POU domain, class 2, transcription factor 1
chr14_+_63436394 0.15 ENSMUST00000121288.1
family with sequence similarity 167, member A
chr12_+_52699297 0.15 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6
chr2_+_28513243 0.15 ENSMUST00000028170.8
ral guanine nucleotide dissociation stimulator
chr9_-_79718518 0.14 ENSMUST00000071750.6
collagen, type XII, alpha 1
chr2_-_32353247 0.14 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
dynamin 1
chr1_-_54194048 0.14 ENSMUST00000120904.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr2_+_10372426 0.14 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Scm-like with four mbt domains 2
chr15_+_82274935 0.14 ENSMUST00000023095.6
septin 3
chr2_-_13011747 0.14 ENSMUST00000061545.5
C1q-like 3
chr15_+_89499598 0.14 ENSMUST00000109309.1
SH3/ankyrin domain gene 3
chr3_+_7366598 0.13 ENSMUST00000028999.6
protein kinase inhibitor, alpha
chr16_-_26989974 0.13 ENSMUST00000089832.4
geminin coiled-coil domain containing
chr2_+_32587057 0.13 ENSMUST00000102818.4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr4_+_42916647 0.13 ENSMUST00000132173.1
ENSMUST00000107975.1
expressed sequence N28178
chr16_+_17451981 0.13 ENSMUST00000006293.3
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr11_+_4986824 0.13 ENSMUST00000009234.9
ENSMUST00000109897.1
adaptor protein complex AP-1, beta 1 subunit
chr6_-_82939676 0.12 ENSMUST00000000641.9
ENSMUST00000113982.1
sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
chr11_-_49712674 0.12 ENSMUST00000020624.6
ENSMUST00000145353.1
CCR4-NOT transcription complex, subunit 6
chr8_+_84021444 0.12 ENSMUST00000055077.6
paralemmin 3
chr16_+_91729281 0.12 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
intersectin 1 (SH3 domain protein 1A)
chr19_+_16132812 0.12 ENSMUST00000025541.5
guanine nucleotide binding protein, alpha q polypeptide
chr1_-_106714217 0.12 ENSMUST00000112751.1
B cell leukemia/lymphoma 2
chrX_+_49470450 0.12 ENSMUST00000114904.3
Rho GTPase activating protein 36
chr15_+_100469034 0.12 ENSMUST00000037001.8
LETM1 domain containing 1
chr6_+_115134899 0.11 ENSMUST00000009538.5
ENSMUST00000169345.1
synapsin II
chr17_+_35916541 0.11 ENSMUST00000087211.2
protein phosphatase 1, regulatory subunit 10
chr5_+_147430407 0.11 ENSMUST00000176600.1
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr4_+_120854786 0.11 ENSMUST00000071093.2
regulating synaptic membrane exocytosis 3
chr5_+_134099704 0.11 ENSMUST00000016088.8
GATS protein-like 2
chr4_-_55532453 0.11 ENSMUST00000132746.1
ENSMUST00000107619.2
Kruppel-like factor 4 (gut)
chr2_-_30903255 0.10 ENSMUST00000102852.3
prostaglandin E synthase
chr11_-_75438900 0.10 ENSMUST00000108437.1
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr1_+_75360321 0.10 ENSMUST00000027409.9
desmin
chr19_-_7105729 0.10 ENSMUST00000113383.2
fibronectin leucine rich transmembrane protein 1
chr11_+_70657196 0.10 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
enolase 3, beta muscle
chr7_+_120842824 0.10 ENSMUST00000047875.8
eukaryotic elongation factor-2 kinase
chr7_+_19076242 0.09 ENSMUST00000032570.7
ENSMUST00000108479.1
dystrophia myotonica-containing WD repeat motif
chr10_-_5922385 0.09 ENSMUST00000131996.1
ENSMUST00000064225.7
regulator of G-protein signaling 17
chr15_-_76817970 0.09 ENSMUST00000175843.1
ENSMUST00000177026.1
ENSMUST00000176736.1
ENSMUST00000036176.8
ENSMUST00000176219.1
ENSMUST00000077821.3
Rho GTPase activating protein 39
chr2_+_65620829 0.09 ENSMUST00000028377.7
sodium channel, voltage-gated, type II, alpha 1
chr9_-_90270712 0.09 ENSMUST00000041767.7
ENSMUST00000144348.1
TBC1 domain family, member 2B
chr2_-_74659861 0.09 ENSMUST00000001867.6
even skipped homeotic gene 2 homolog
chr11_+_75630974 0.09 ENSMUST00000006286.2
inositol polyphosphate 5-phosphatase K
chr1_-_152090308 0.09 ENSMUST00000044581.7
RIKEN cDNA 1700025G04 gene
chr15_-_102257449 0.09 ENSMUST00000043172.8
retinoic acid receptor, gamma
chr19_-_6840590 0.09 ENSMUST00000170516.2
ENSMUST00000025903.5
ribosomal protein S6 kinase, polypeptide 4
chr2_-_152398046 0.09 ENSMUST00000063332.8
ENSMUST00000182625.1
SRY-box containing gene 12
chr4_-_141790891 0.09 ENSMUST00000038014.4
ENSMUST00000153880.1
DnaJ (Hsp40) homolog, subfamily C, member 16
chr8_-_57653023 0.09 ENSMUST00000034021.5
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr6_-_52234902 0.08 ENSMUST00000125581.1
homeobox A10
chrX_+_56346390 0.08 ENSMUST00000101560.3
zinc finger protein 449
chr7_-_84086494 0.08 ENSMUST00000064174.5
RIKEN cDNA 9930013L23 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of GGCAGUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.3 0.8 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.6 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.4 GO:0097350 neutrophil clearance(GO:0097350)
0.1 0.5 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.2 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1 1.0 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.8 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 0.1 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740)
0.1 1.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1 0.3 GO:0045763 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 0.1 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 0.5 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.3 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.1 2.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 0.3 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 1.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.4 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.1 0.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.3 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.7 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.3 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) bile acid signaling pathway(GO:0038183)
0.1 0.5 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.6 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.5 GO:0060022 hard palate development(GO:0060022)
0.1 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.6 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.2 GO:0071462 cellular response to water stimulus(GO:0071462)
0.1 0.2 GO:0021943 formation of radial glial scaffolds(GO:0021943) negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.2 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.1 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.4 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.2 GO:0042117 monocyte activation(GO:0042117)
0.0 0.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 1.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0 1.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.1 GO:2000325 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.6 GO:0042711 maternal behavior(GO:0042711)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.4 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.0 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.3 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.5 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:1903918 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.6 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.3 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.4 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0010039 response to iron ion(GO:0010039)
0.0 0.3 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.3 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 1.0 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0019660 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0043511 inhibin complex(GO:0043511)
0.3 2.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 0.6 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.5 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.4 GO:0071953 elastic fiber(GO:0071953)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.1 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.2 GO:0042272 nucleocytoplasmic shuttling complex(GO:0031074) nuclear RNA export factor complex(GO:0042272)
0.1 0.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.1 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0097513 uropod(GO:0001931) cell trailing edge(GO:0031254) myosin II filament(GO:0097513)
0.0 0.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.3 1.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.8 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 1.3 GO:0034711 inhibin binding(GO:0034711)
0.1 1.0 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.3 GO:1902121 lithocholic acid binding(GO:1902121) D3 vitamins binding(GO:1902271)
0.1 0.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.5 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.4 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 3.7 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 1.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 3.3 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.5 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.7 PID IGF1 PATHWAY IGF1 pathway
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters