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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Gfi1_Gfi1b

Z-value: 2.07

Motif logo

Transcription factors associated with Gfi1_Gfi1b

Gene Symbol Gene ID Gene Info
ENSMUSG00000029275.11 growth factor independent 1 transcription repressor
ENSMUSG00000026815.8 growth factor independent 1B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gfi1mm10_v2_chr5_-_107723954_107723974-0.811.5e-09Click!
Gfi1bmm10_v2_chr2_-_28621932_28621982-0.812.1e-09Click!

Activity profile of Gfi1_Gfi1b motif

Sorted Z-values of Gfi1_Gfi1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_127759780 10.76 ENSMUST00000128247.1
Protein Rdh9
chr5_-_87091150 7.79 ENSMUST00000154455.1
UDP glucuronosyltransferase 2 family, polypeptide B36
chr6_+_121838514 7.34 ENSMUST00000032228.8
murinoglobulin 1
chr6_+_122006798 6.69 ENSMUST00000081777.6
murinoglobulin 2
chr8_+_46010596 6.01 ENSMUST00000110381.2
Lrp2 binding protein
chr15_+_6445320 5.45 ENSMUST00000022749.9
complement component 9
chr6_-_127109517 4.95 ENSMUST00000039913.8
RIKEN cDNA 9630033F20 gene
chr10_-_127370535 4.75 ENSMUST00000026472.8
inhibin beta-C
chr5_+_90891234 4.61 ENSMUST00000031327.8
chemokine (C-X-C motif) ligand 1
chr1_+_167618246 4.49 ENSMUST00000111380.1
retinoid X receptor gamma
chr16_-_46010212 4.46 ENSMUST00000130481.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr10_-_128960965 4.37 ENSMUST00000026398.3
methyltransferase like 7B
chr3_+_138415484 3.96 ENSMUST00000161312.1
ENSMUST00000013458.8
alcohol dehydrogenase 4 (class II), pi polypeptide
chr4_-_49408042 3.93 ENSMUST00000081541.2
acyl-coenzyme A amino acid N-acyltransferase 2
chr14_+_55560904 3.91 ENSMUST00000072530.4
ENSMUST00000128490.1
DDB1 and CUL4 associated factor 11
chr3_-_98630309 3.86 ENSMUST00000044094.4
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
chr11_+_101367542 3.81 ENSMUST00000019469.2
glucose-6-phosphatase, catalytic
chr4_-_108118504 3.64 ENSMUST00000149106.1
sterol carrier protein 2, liver
chr8_-_117673682 3.60 ENSMUST00000173522.1
ENSMUST00000174450.1
short chain dehydrogenase/reductase family 42E, member 1
chr7_+_51878967 3.47 ENSMUST00000051912.6
growth arrest specific 2
chr1_+_60908993 3.37 ENSMUST00000027164.2
cytotoxic T-lymphocyte-associated protein 4
chr19_-_20727533 3.37 ENSMUST00000025656.3
aldehyde dehydrogenase family 1, subfamily A7
chr1_+_93512079 3.36 ENSMUST00000120301.1
ENSMUST00000041983.4
ENSMUST00000122402.1
FERM, RhoGEF and pleckstrin domain protein 2
chr19_-_34877880 3.34 ENSMUST00000112460.1
pantothenate kinase 1
chr2_-_160872552 3.22 ENSMUST00000103111.2
zinc fingers and homeoboxes 3
chr7_+_51879041 3.21 ENSMUST00000107591.2
growth arrest specific 2
chr18_-_74961252 3.20 ENSMUST00000066532.4
lipase, endothelial
chr10_-_109010955 3.16 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr4_-_108118528 3.01 ENSMUST00000030340.8
sterol carrier protein 2, liver
chr16_+_38089001 2.97 ENSMUST00000023507.6
glycogen synthase kinase 3 beta
chr8_-_61591130 2.97 ENSMUST00000135439.1
ENSMUST00000121200.1
palladin, cytoskeletal associated protein
chr1_-_169747634 2.94 ENSMUST00000027991.5
ENSMUST00000111357.1
regulator of G-protein signaling 4
chr2_-_110305730 2.92 ENSMUST00000046233.2
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr12_-_98577940 2.87 ENSMUST00000110113.1
potassium channel, subfamily K, member 10
chr14_+_55560480 2.86 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
DDB1 and CUL4 associated factor 11
chr8_-_84893887 2.78 ENSMUST00000003907.7
ENSMUST00000182458.1
ENSMUST00000109745.1
ENSMUST00000142748.1
glutaryl-Coenzyme A dehydrogenase
chr1_+_167598450 2.77 ENSMUST00000111386.1
ENSMUST00000111384.1
retinoid X receptor gamma
chr1_-_9962809 2.74 ENSMUST00000097824.2
predicted gene 10567
chr11_+_112782182 2.71 ENSMUST00000000579.2
SRY-box containing gene 9
chr2_+_58754910 2.62 ENSMUST00000059102.6
uridine phosphorylase 2
chr19_+_12633507 2.61 ENSMUST00000119960.1
glycine-N-acyltransferase
chr7_-_99626936 2.59 ENSMUST00000178124.1
predicted gene 4980
chr13_-_71963713 2.59 ENSMUST00000077337.8
Iroquois related homeobox 1 (Drosophila)
chr19_-_32061438 2.55 ENSMUST00000096119.4
N-acylsphingosine amidohydrolase 2
chr6_-_89216237 2.52 ENSMUST00000079186.2
predicted gene 839
chr1_+_167598384 2.51 ENSMUST00000015987.3
retinoid X receptor gamma
chr17_+_64600702 2.51 ENSMUST00000086723.3
mannosidase 2, alpha 1
chr10_+_127759721 2.49 ENSMUST00000073639.5
retinol dehydrogenase 1 (all trans)
chr2_+_109917639 2.43 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr9_-_50555170 2.42 ENSMUST00000119103.1
beta-carotene oxygenase 2
chr12_+_108334341 2.39 ENSMUST00000021684.4
cytochrome P450, family 46, subfamily a, polypeptide 1
chr8_-_93229517 2.38 ENSMUST00000176282.1
ENSMUST00000034173.7
carboxylesterase 1E
chr5_+_43662373 2.31 ENSMUST00000048150.8
coiled-coil and C2 domain containing 2A
chr2_-_35100677 2.29 ENSMUST00000045776.4
ENSMUST00000113050.3
expressed sequence AI182371
chr7_-_139582790 2.26 ENSMUST00000106095.2
NK6 homeobox 2
chr2_-_58052832 2.21 ENSMUST00000090940.5
ermin, ERM-like protein
chr5_+_102768771 2.20 ENSMUST00000112852.1
Rho GTPase activating protein 24
chr6_+_121300227 2.18 ENSMUST00000064580.7
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr2_+_58755177 2.18 ENSMUST00000102755.3
uridine phosphorylase 2
chr3_+_138374121 2.17 ENSMUST00000171054.1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr8_-_91801948 2.12 ENSMUST00000175795.1
Iroquois related homeobox 3 (Drosophila)
chr3_+_94372794 2.10 ENSMUST00000029795.3
RAR-related orphan receptor gamma
chr11_-_31671727 2.08 ENSMUST00000109415.1
biorientation of chromosomes in cell division 1
chr1_-_65179058 2.05 ENSMUST00000097709.4
isocitrate dehydrogenase 1 (NADP+), soluble
chrX_-_75875101 2.04 ENSMUST00000114059.3
plastin 3 (T-isoform)
chrX_-_8193387 2.03 ENSMUST00000143223.1
ENSMUST00000033509.8
phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr4_+_136143497 2.03 ENSMUST00000008016.2
inhibitor of DNA binding 3
chr5_-_88676135 2.03 ENSMUST00000078945.5
G-rich RNA sequence binding factor 1
chr1_-_140183404 2.01 ENSMUST00000066859.6
ENSMUST00000111976.2
complement component factor h
chr9_-_103219823 2.00 ENSMUST00000168142.1
transferrin
chr1_-_140183283 1.99 ENSMUST00000111977.1
complement component factor h
chr7_-_19796789 1.96 ENSMUST00000108449.2
ENSMUST00000043822.7
Casitas B-lineage lymphoma c
chr1_-_168431695 1.95 ENSMUST00000176790.1
pre B cell leukemia homeobox 1
chr10_+_34297421 1.94 ENSMUST00000047935.6
TSPY-like 4
chr17_-_12940317 1.93 ENSMUST00000160378.1
ENSMUST00000043923.5
acetyl-Coenzyme A acetyltransferase 3
chr11_-_70514608 1.92 ENSMUST00000021179.3
vitelline membrane outer layer 1 homolog (chicken)
chr7_+_19489045 1.91 ENSMUST00000011407.7
ENSMUST00000137613.1
exocyst complex component 3-like 2
chr14_-_36968679 1.90 ENSMUST00000067700.6
coiled-coil serine rich 2
chr1_+_169969409 1.87 ENSMUST00000180638.1
RIKEN cDNA 3110045C21 gene
chr2_-_52335134 1.87 ENSMUST00000075301.3
nebulin
chr2_-_150451486 1.86 ENSMUST00000109916.1
zinc finger protein 442
chr9_-_21927515 1.82 ENSMUST00000178988.1
ENSMUST00000046831.9
transmembrane protein 205
chr18_-_61536522 1.82 ENSMUST00000171629.1
Rho guanine nucleotide exchange factor (GEF) 37
chr7_+_44590886 1.80 ENSMUST00000107906.3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr12_-_56613270 1.79 ENSMUST00000072631.5
NK2 homeobox 9
chr11_-_86993682 1.79 ENSMUST00000018571.4
yippee-like 2 (Drosophila)
chr13_-_56548534 1.78 ENSMUST00000062806.4
leukocyte cell-derived chemotaxin 2
chr14_+_21052574 1.77 ENSMUST00000045376.9
adenosine kinase
chr9_+_77921908 1.76 ENSMUST00000133757.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr6_+_82041623 1.76 ENSMUST00000042974.8
eva-1 homolog A (C. elegans)
chr4_-_41640322 1.76 ENSMUST00000127306.1
energy homeostasis associated
chr16_+_45093611 1.72 ENSMUST00000099498.2
coiled-coil domain containing 80
chr8_-_83955205 1.70 ENSMUST00000098595.2
predicted gene 10644
chr8_-_3878549 1.67 ENSMUST00000011445.6
CD209d antigen
chr4_-_104876383 1.67 ENSMUST00000064873.8
ENSMUST00000106808.3
ENSMUST00000048947.8
complement component 8, alpha polypeptide
chr11_+_117232254 1.66 ENSMUST00000106354.2
septin 9
chr15_-_55113460 1.65 ENSMUST00000100659.2
ENSMUST00000110230.1
predicted gene 9920
chr4_-_109156610 1.65 ENSMUST00000161363.1
oxysterol binding protein-like 9
chr6_+_129180613 1.64 ENSMUST00000032260.5
C-type lectin domain family 2, member d
chr9_+_21927471 1.59 ENSMUST00000170304.1
ENSMUST00000006403.6
coiled-coil domain containing 159
chr9_+_70207342 1.58 ENSMUST00000034745.7
myosin IE
chr17_-_47421873 1.52 ENSMUST00000073143.6
RIKEN cDNA 1700001C19 gene
chr14_-_61556746 1.52 ENSMUST00000100496.4
SPRY domain containing 7
chr6_-_23132981 1.52 ENSMUST00000031707.7
aminoadipate-semialdehyde synthase
chr7_-_25539845 1.51 ENSMUST00000066503.7
ENSMUST00000064862.6
carcinoembryonic antigen-related cell adhesion molecule 2
chr13_+_4049001 1.49 ENSMUST00000118717.2
aldo-keto reductase family 1, member C14
chr6_-_72362382 1.47 ENSMUST00000114095.1
ENSMUST00000069595.6
ENSMUST00000069580.5
ring finger protein 181
chr4_+_89137122 1.45 ENSMUST00000058030.7
methylthioadenosine phosphorylase
chr7_-_137410717 1.45 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
RIKEN cDNA 9430038I01 gene
chr4_+_97777780 1.45 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
nuclear factor I/A
chr10_-_54075730 1.44 ENSMUST00000105469.1
ENSMUST00000003843.8
mannosidase 1, alpha
chr11_+_83709015 1.44 ENSMUST00000001009.7
WAP four-disulfide core domain 18
chr13_+_63015167 1.43 ENSMUST00000021911.8
RIKEN cDNA 2010111I01 gene
chrX_-_147429189 1.42 ENSMUST00000033646.2
interleukin 13 receptor, alpha 2
chr2_-_104742802 1.42 ENSMUST00000028595.7
DEP domain containing 7
chr4_+_135946447 1.42 ENSMUST00000030432.7
3-hydroxy-3-methylglutaryl-Coenzyme A lyase
chr14_+_55559993 1.41 ENSMUST00000117236.1
DDB1 and CUL4 associated factor 11
chr4_+_43046014 1.40 ENSMUST00000180426.1
predicted gene, 26881
chr14_+_123659971 1.39 ENSMUST00000049681.7
integrin, beta-like 1
chr17_-_46032366 1.39 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
vascular endothelial growth factor A
chr14_-_55560340 1.39 ENSMUST00000066106.3
RIKEN cDNA A730061H03 gene
chr8_-_77610597 1.38 ENSMUST00000034030.8
transmembrane protein 184C
chr1_-_169969143 1.38 ENSMUST00000027989.6
ENSMUST00000111353.3
hydroxysteroid (17-beta) dehydrogenase 7
chr7_+_101378183 1.37 ENSMUST00000084895.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_-_36058371 1.37 ENSMUST00000113742.2
predicted gene 11127
chr13_-_62888282 1.36 ENSMUST00000092888.4
fructose bisphosphatase 1
chr1_+_152399824 1.36 ENSMUST00000044311.8
collagen beta(1-O)galactosyltransferase 2
chr13_+_55714624 1.36 ENSMUST00000021959.9
thioredoxin domain containing 15
chr19_+_46623387 1.35 ENSMUST00000111855.4
WW domain binding protein 1 like
chrX_+_38600626 1.34 ENSMUST00000000365.2
malignant T cell amplified sequence 1
chr10_+_94036001 1.34 ENSMUST00000020208.4
FYVE, RhoGEF and PH domain containing 6
chrX_+_142226765 1.34 ENSMUST00000112916.2
nuclear transport factor 2-like export factor 2
chr14_+_12189943 1.33 ENSMUST00000119888.1
protein tyrosine phosphatase, receptor type, G
chrX_+_103356464 1.33 ENSMUST00000116547.2
cysteine-rich hydrophobic domain 1
chr2_+_127270208 1.33 ENSMUST00000110375.2
START domain containing 7
chr8_+_45627709 1.33 ENSMUST00000134321.1
ENSMUST00000135336.1
sorbin and SH3 domain containing 2
chr7_-_45103747 1.32 ENSMUST00000003512.7
Fc receptor, IgG, alpha chain transporter
chrX_+_129749740 1.32 ENSMUST00000167619.2
ENSMUST00000037854.8
diaphanous homolog 2 (Drosophila)
chr14_+_55560010 1.32 ENSMUST00000147981.1
ENSMUST00000133256.1
DDB1 and CUL4 associated factor 11
chr4_+_116596672 1.32 ENSMUST00000051869.7
coiled-coil domain containing 17
chr19_+_26749726 1.31 ENSMUST00000175842.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_19957037 1.31 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
ceruloplasmin
chr13_+_42301270 1.30 ENSMUST00000021796.7
endothelin 1
chr7_-_5805445 1.30 ENSMUST00000075085.6
vomeronasal 1 receptor 63
chr8_-_77610668 1.29 ENSMUST00000141202.1
ENSMUST00000152168.1
transmembrane protein 184C
chr4_+_43406435 1.29 ENSMUST00000098106.2
ENSMUST00000139198.1
RUN and SH3 domain containing 2
chr4_+_150855064 1.29 ENSMUST00000030811.1
ERBB receptor feedback inhibitor 1
chr17_-_34959232 1.29 ENSMUST00000165202.1
ENSMUST00000172753.1
heat shock protein 1B
chrX_+_129749830 1.28 ENSMUST00000113320.2
diaphanous homolog 2 (Drosophila)
chr15_+_99295087 1.27 ENSMUST00000128352.1
ENSMUST00000145482.1
PRP40 pre-mRNA processing factor 40 homolog B (yeast)
chr11_-_11898044 1.27 ENSMUST00000066237.3
dopa decarboxylase
chr9_+_20581296 1.26 ENSMUST00000115557.2
zinc finger protein 846
chr16_+_45094036 1.26 ENSMUST00000061050.5
coiled-coil domain containing 80
chr4_-_154899077 1.26 ENSMUST00000030935.3
ENSMUST00000132281.1
family with sequence similarity 213, member B
chr9_+_44084944 1.25 ENSMUST00000176416.1
ENSMUST00000065461.7
ubiquitin specific peptidase 2
chr11_+_94328242 1.24 ENSMUST00000021227.5
ankyrin repeat domain 40
chr8_-_41215146 1.23 ENSMUST00000034003.4
fibrinogen-like protein 1
chr10_+_18469958 1.23 ENSMUST00000162891.1
ENSMUST00000100054.3
NHS-like 1
chr7_+_66079643 1.22 ENSMUST00000101801.5
VCP-interacting membrane protein
chr8_-_72435043 1.22 ENSMUST00000109974.1
calreticulin 3
chr4_-_6275629 1.22 ENSMUST00000029905.1
cytochrome P450, family 7, subfamily a, polypeptide 1
chr11_-_11898092 1.22 ENSMUST00000178704.1
dopa decarboxylase
chr2_+_177897096 1.22 ENSMUST00000108935.1
predicted gene 14327
chr14_-_72602945 1.21 ENSMUST00000162825.1
fibronectin type III domain containing 3A
chr1_+_185332143 1.21 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
bisphosphate 3'-nucleotidase 1
chr11_+_87592145 1.21 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
myotubularin related protein 4
chr1_+_21240581 1.21 ENSMUST00000027067.8
glutathione S-transferase, alpha 3
chr1_+_21240597 1.20 ENSMUST00000121676.1
glutathione S-transferase, alpha 3
chr17_-_46890405 1.20 ENSMUST00000086675.3
RIKEN cDNA A330017A19 gene
chr17_+_36121666 1.20 ENSMUST00000173128.1
predicted gene, 19684
chr7_-_80405425 1.19 ENSMUST00000107362.3
ENSMUST00000135306.1
furin (paired basic amino acid cleaving enzyme)
chr10_-_89506631 1.18 ENSMUST00000058126.8
ENSMUST00000105296.2
nuclear receptor subfamily 1, group H, member 4
chr5_-_137684665 1.18 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
ArfGAP with FG repeats 2
chr8_-_3748941 1.17 ENSMUST00000012847.1
CD209a antigen
chr3_-_107943705 1.17 ENSMUST00000106680.1
ENSMUST00000106684.1
ENSMUST00000106685.2
glutathione S-transferase, mu 6
chr17_-_91092715 1.15 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
neurexin I
chr13_+_16011851 1.15 ENSMUST00000042603.6
inhibin beta-A
chr10_-_75780954 1.15 ENSMUST00000173512.1
ENSMUST00000173537.1
predicted gene 20441
glutathione S-transferase, theta 3
chr2_+_143915273 1.15 ENSMUST00000103172.3
destrin
chr13_+_9276477 1.15 ENSMUST00000174552.1
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr7_-_140116395 1.14 ENSMUST00000026538.6
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
chr1_+_88138364 1.14 ENSMUST00000014263.4
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr7_-_25754701 1.13 ENSMUST00000108401.1
ENSMUST00000043765.7
heterogeneous nuclear ribonucleoprotein U-like 1
chr2_-_64975762 1.13 ENSMUST00000156765.1
growth factor receptor bound protein 14
chr4_+_97777606 1.13 ENSMUST00000075448.6
ENSMUST00000092532.6
nuclear factor I/A
chr11_+_70540064 1.13 ENSMUST00000157075.1
phospholipase D2
chr11_+_95842283 1.12 ENSMUST00000107714.2
ENSMUST00000107711.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr3_-_97297778 1.12 ENSMUST00000181368.1
predicted gene, 17608
chr11_+_71019593 1.12 ENSMUST00000133413.1
ENSMUST00000164220.1
ENSMUST00000048807.5
MIS12 homolog (yeast)
chr11_-_115187827 1.11 ENSMUST00000103041.1
N-acetyltransferase 9 (GCN5-related, putative)
chr3_-_148989316 1.10 ENSMUST00000098518.2
latrophilin 2
chr7_+_4237699 1.10 ENSMUST00000117550.1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr5_-_66151903 1.09 ENSMUST00000167950.1
RNA binding motif protein 47
chr2_-_26092149 1.09 ENSMUST00000114159.2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr7_-_101933815 1.09 ENSMUST00000106963.1
ENSMUST00000106966.1
leucine rich repeat containing 51
chr19_+_11912389 1.09 ENSMUST00000061618.7
protein associated with topoisomerase II homolog 1 (yeast)
chr14_-_45530118 1.08 ENSMUST00000045905.6
fermitin family homolog 2 (Drosophila)
chr6_-_87851011 1.08 ENSMUST00000113617.1
cellular nucleic acid binding protein
chr11_-_23770953 1.08 ENSMUST00000102864.3
reticuloendotheliosis oncogene
chr19_+_44989073 1.07 ENSMUST00000026225.8
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

Network of associatons between targets according to the STRING database.

First level regulatory network of Gfi1_Gfi1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.6 GO:0032385 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
1.5 4.6 GO:0070949 neutrophil mediated killing of fungus(GO:0070947) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
1.1 3.4 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
1.0 3.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
1.0 4.0 GO:0006069 ethanol oxidation(GO:0006069)
0.9 2.7 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.8 2.4 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.8 2.4 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377)
0.8 3.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.8 3.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.8 12.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 2.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.7 2.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.7 4.7 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.6 3.9 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.6 1.9 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.6 3.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.5 1.5 GO:0006553 lysine metabolic process(GO:0006553)
0.5 1.5 GO:0070342 brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347)
0.4 1.2 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.4 2.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.4 1.5 GO:0002188 translation reinitiation(GO:0002188)
0.4 1.1 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.4 0.7 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.4 1.1 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.4 2.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.4 1.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.3 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.3 1.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 1.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.3 2.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 2.3 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 4.5 GO:0036315 cellular response to sterol(GO:0036315)
0.3 1.6 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.3 5.8 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.3 1.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 1.2 GO:0090472 dibasic protein processing(GO:0090472)
0.3 1.2 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.3 3.2 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 2.0 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.3 2.5 GO:0006013 mannose metabolic process(GO:0006013)
0.3 1.3 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.3 9.9 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.2 1.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.2 2.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 3.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 3.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 0.9 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 1.5 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.2 0.6 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.2 0.6 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2 0.6 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.2 0.6 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 2.6 GO:0072189 ureter development(GO:0072189)
0.2 3.4 GO:0016322 neuron remodeling(GO:0016322)
0.2 2.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 0.9 GO:0032349 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.2 0.6 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 0.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 1.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 0.6 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.2 0.2 GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.2 0.7 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 1.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 1.4 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.2 0.7 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 1.7 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.8 GO:0061744 motor behavior(GO:0061744)
0.2 1.9 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2 1.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 2.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 0.9 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.2 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.4 GO:0070268 cornification(GO:0070268)
0.1 1.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.3 GO:0031179 peptide modification(GO:0031179)
0.1 1.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 3.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.7 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 4.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1 0.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.9 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.7 GO:0098961 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 0.7 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 1.9 GO:0051601 exocyst localization(GO:0051601)
0.1 0.7 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.9 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 1.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.4 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 3.1 GO:0035634 response to stilbenoid(GO:0035634)
0.1 0.3 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.4 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 0.4 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 2.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 1.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.3 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.4 GO:1901146 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 5.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 2.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.5 GO:0001523 retinoid metabolic process(GO:0001523)
0.1 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 1.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.0 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 2.0 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 0.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.6 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.1 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.1 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.1 0.2 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.9 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.1 2.9 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.1 1.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.9 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 1.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.7 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.0 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.1 0.2 GO:0043519 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.1 14.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.1 GO:0072431 signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.1 1.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 0.5 GO:0007343 egg activation(GO:0007343)
0.1 0.6 GO:0048733 histone H3-K36 methylation(GO:0010452) sebaceous gland development(GO:0048733)
0.1 0.7 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 10.3 GO:0008360 regulation of cell shape(GO:0008360)
0.1 1.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.3 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 3.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 1.3 GO:0046688 response to copper ion(GO:0046688)
0.0 3.9 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.7 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.7 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 2.3 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.5 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 1.1 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 2.0 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:2000503 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.8 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 1.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:2000412 tolerance induction to self antigen(GO:0002513) positive regulation of thymocyte migration(GO:2000412)
0.0 0.5 GO:0060013 righting reflex(GO:0060013)
0.0 1.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 1.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699) development of secondary male sexual characteristics(GO:0046544)
0.0 0.1 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583) short-chain fatty acid metabolic process(GO:0046459)
0.0 1.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 1.6 GO:0001656 metanephros development(GO:0001656)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.6 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.6 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 1.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 1.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.0 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
0.0 1.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0042670 amacrine cell differentiation(GO:0035881) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.4 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.8 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.4 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0 0.7 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 2.8 GO:0016042 lipid catabolic process(GO:0016042)
0.0 1.9 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.2 GO:0060347 heart trabecula formation(GO:0060347)
0.0 1.2 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 2.6 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 0.6 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 2.2 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 1.2 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.0 GO:0071873 epinephrine metabolic process(GO:0042414) response to norepinephrine(GO:0071873)
0.0 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 1.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 1.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.2 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.6 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.5 4.1 GO:0045098 type III intermediate filament(GO:0045098)
0.5 1.9 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.4 1.8 GO:0097447 dendritic tree(GO:0097447)
0.4 1.1 GO:0043512 inhibin A complex(GO:0043512)
0.3 3.2 GO:0005579 membrane attack complex(GO:0005579)
0.3 1.9 GO:0032437 cuticular plate(GO:0032437)
0.3 4.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 11.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 2.2 GO:0033269 internode region of axon(GO:0033269)
0.3 1.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 3.0 GO:1990909 Wnt signalosome(GO:1990909)
0.2 2.2 GO:0097433 dense body(GO:0097433)
0.2 1.9 GO:0030478 actin cap(GO:0030478)
0.2 0.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.2 0.9 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.2 0.6 GO:0043159 acrosomal matrix(GO:0043159)
0.2 0.9 GO:0002079 inner acrosomal membrane(GO:0002079)
0.2 0.7 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 3.2 GO:0031045 dense core granule(GO:0031045)
0.2 1.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 0.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 4.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.3 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 1.8 GO:0036038 MKS complex(GO:0036038)
0.1 0.8 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 2.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 3.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.7 GO:0031105 septin complex(GO:0031105)
0.1 0.3 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.1 0.7 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 1.6 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 1.9 GO:0000145 exocyst(GO:0000145)
0.1 3.5 GO:0030118 clathrin coat(GO:0030118)
0.1 1.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.1 GO:0001739 sex chromatin(GO:0001739)
0.1 1.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 3.0 GO:0002102 podosome(GO:0002102)
0.1 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.6 GO:0042587 glycogen granule(GO:0042587)
0.1 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.8 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 6.8 GO:0072562 blood microparticle(GO:0072562)
0.0 2.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 4.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.7 GO:0042641 actomyosin(GO:0042641)
0.0 1.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.4 GO:0032994 protein-lipid complex(GO:0032994)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 5.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 3.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.7 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 6.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 3.8 GO:0005938 cell cortex(GO:0005938)
0.0 2.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.1 GO:0005769 early endosome(GO:0005769)
0.0 2.0 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 2.8 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 2.0 GO:0005770 late endosome(GO:0005770)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 2.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
1.7 6.6 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
1.3 4.0 GO:0004024 NADPH:quinone reductase activity(GO:0003960) alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.3 3.8 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.1 3.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.0 9.8 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.0 4.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.8 3.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.8 3.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 2.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.7 3.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.6 1.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.6 2.5 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.6 4.0 GO:0001851 complement component C3b binding(GO:0001851)
0.5 7.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.5 3.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.5 1.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.5 1.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 2.5 GO:0017040 ceramidase activity(GO:0017040)
0.4 2.1 GO:0008142 oxysterol binding(GO:0008142)
0.4 2.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.4 4.0 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.4 4.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 1.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 1.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 1.9 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.3 1.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.3 5.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 0.9 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 2.0 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 1.3 GO:0019770 IgG receptor activity(GO:0019770)
0.3 2.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 0.7 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 1.5 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 1.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.2 8.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.6 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 0.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.2 0.8 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 6.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 1.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 1.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 2.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.5 GO:0004771 sterol esterase activity(GO:0004771)
0.2 0.7 GO:0036033 mediator complex binding(GO:0036033)
0.2 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 2.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.8 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.1 0.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 2.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.8 GO:0019206 nucleoside kinase activity(GO:0019206)
0.1 2.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.4 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 1.0 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.1 0.6 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 2.6 GO:0005537 mannose binding(GO:0005537)
0.1 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 2.1 GO:0001848 complement binding(GO:0001848)
0.1 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.4 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.1 1.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 5.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 4.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 3.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 12.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 3.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 1.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0043199 sulfate binding(GO:0043199)
0.1 0.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.5 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 1.9 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.8 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 3.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 2.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 1.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 5.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.9 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.5 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 2.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.0 GO:0000149 SNARE binding(GO:0000149)
0.0 1.1 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 10.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 4.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 5.3 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.3 PID ARF 3PATHWAY Arf1 pathway
0.1 5.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 4.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.6 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 5.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.7 5.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.5 2.0 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.4 14.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.4 10.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.3 4.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 3.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 2.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 3.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 6.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 12.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 2.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 3.9 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 1.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 1.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 5.0 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 5.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 2.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 0.7 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 6.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.6 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis