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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hoxa11_Hoxc12

Z-value: 0.94

Motif logo

Transcription factors associated with Hoxa11_Hoxc12

Gene Symbol Gene ID Gene Info
ENSMUSG00000038210.9 homeobox A11
ENSMUSG00000050328.2 homeobox C12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa11mm10_v2_chr6_-_52246214_52246214-0.009.9e-01Click!

Activity profile of Hoxa11_Hoxc12 motif

Sorted Z-values of Hoxa11_Hoxc12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39287074 4.54 ENSMUST00000003137.8
cytochrome P450, family 2, subfamily c, polypeptide 29
chr4_-_62150810 1.99 ENSMUST00000077719.3
major urinary protein 21
chr3_+_81996922 1.79 ENSMUST00000029641.3
acid-sensing (proton-gated) ion channel family member 5
chr2_+_23068168 1.34 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
acyl-Coenzyme A binding domain containing 5
chr17_+_22361453 1.33 ENSMUST00000149699.1
ENSMUST00000088765.2
ENSMUST00000072477.4
ENSMUST00000121315.1
zinc finger protein 758
chr16_-_16600533 1.28 ENSMUST00000159542.1
FYVE, RhoGEF and PH domain containing 4
chr11_-_30986326 1.25 ENSMUST00000020553.4
ENSMUST00000101394.4
ChaC, cation transport regulator 2
chr17_-_21845759 1.15 ENSMUST00000084141.4
zinc finger protein 820
chr18_-_38209762 1.09 ENSMUST00000057185.6
protocadherin 1
chr18_-_10706688 1.04 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
abhydrolase domain containing 3
chr16_-_57231434 1.00 ENSMUST00000023431.6
TBC1 domain family, member 23
chr12_+_78226627 1.00 ENSMUST00000110388.2
ENSMUST00000052472.4
gephyrin
chr5_-_123666682 0.95 ENSMUST00000149410.1
CAP-GLY domain containing linker protein 1
chr11_-_62457772 0.91 ENSMUST00000127471.2
nuclear receptor co-repressor 1
chr19_+_5406815 0.91 ENSMUST00000174412.1
ENSMUST00000153017.2
RIKEN cDNA 4930481A15 gene
chr2_-_180824596 0.89 ENSMUST00000148700.1
predicted gene 14340
chr6_+_149141638 0.88 ENSMUST00000166416.1
ENSMUST00000111551.1
methyltransferase like 20
chr7_-_135528645 0.88 ENSMUST00000053716.7
clarin 3
chr2_+_131133497 0.87 ENSMUST00000110225.1
predicted gene 11037
chr7_-_73537621 0.86 ENSMUST00000172704.1
chromodomain helicase DNA binding protein 2
chr8_-_69373914 0.82 ENSMUST00000095282.1
predicted gene 10311
chr9_+_3404058 0.81 ENSMUST00000027027.5
CWF19-like 2, cell cycle control (S. pombe)
chr14_+_49172202 0.80 ENSMUST00000153488.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr1_-_182409020 0.79 ENSMUST00000097444.1
predicted gene 10517
chr6_+_149141513 0.78 ENSMUST00000047531.9
ENSMUST00000179873.1
ENSMUST00000111548.1
ENSMUST00000111547.1
ENSMUST00000134306.1
methyltransferase like 20
chr8_+_45069374 0.76 ENSMUST00000130141.1
melatonin receptor 1A
chr9_-_50659780 0.75 ENSMUST00000034567.3
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr5_+_119625939 0.75 ENSMUST00000156235.1
predicted gene 16063
chr1_+_88087802 0.71 ENSMUST00000113139.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr7_-_120145286 0.69 ENSMUST00000033207.4
zona pellucida glycoprotein 2
chr9_+_37613806 0.69 ENSMUST00000002007.3
sialic acid acetylesterase
chr5_+_32611171 0.68 ENSMUST00000072311.6
ENSMUST00000168707.2
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
chr13_+_65512678 0.68 ENSMUST00000081471.2
predicted gene 10139
chrX_-_165004829 0.65 ENSMUST00000114890.2
predicted gene, 17604
chr1_-_136960427 0.65 ENSMUST00000027649.7
nuclear receptor subfamily 5, group A, member 2
chr9_+_75441518 0.64 ENSMUST00000048937.4
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr18_+_37655891 0.64 ENSMUST00000097608.2
RIKEN cDNA 3222401L13 gene
chr1_+_178529113 0.62 ENSMUST00000161017.1
kinesin family member 26B
chr6_+_29471437 0.62 ENSMUST00000171317.1
predicted gene 9047
chr1_-_173227229 0.59 ENSMUST00000049706.5
Fc receptor, IgE, high affinity I, alpha polypeptide
chr14_+_27622433 0.59 ENSMUST00000090302.5
ELKS/RAB6-interacting/CAST family member 2
chr11_-_72267141 0.57 ENSMUST00000137701.1
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr13_-_12464925 0.56 ENSMUST00000124888.1
lectin, galactose binding, soluble 8
chr17_+_75465538 0.56 ENSMUST00000095204.4
RAS, guanyl releasing protein 3
chr8_-_69625503 0.54 ENSMUST00000121886.1
zinc finger protein 868
chr11_-_23895208 0.54 ENSMUST00000102863.2
ENSMUST00000020513.3
poly(A) polymerase gamma
chr7_-_119895446 0.52 ENSMUST00000098080.2
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr19_+_4097392 0.50 ENSMUST00000174514.1
ENSMUST00000174149.1
CDK2-associated protein 2
chr11_-_115627948 0.48 ENSMUST00000154623.1
ENSMUST00000106503.3
ENSMUST00000141614.1
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr7_-_141435327 0.48 ENSMUST00000138865.1
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr14_-_34503323 0.47 ENSMUST00000171343.1
bone morphogenetic protein receptor, type 1A
chr6_+_91878034 0.47 ENSMUST00000037783.5
coiled-coil domain containing 174
chr19_+_29945782 0.47 ENSMUST00000025724.8
interleukin 33
chr17_+_8182247 0.46 ENSMUST00000161898.1
Fgfr1 oncogene partner
chr3_+_32436376 0.45 ENSMUST00000108242.1
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr3_+_69721985 0.44 ENSMUST00000029358.8
NMD3 homolog (S. cerevisiae)
chr4_+_136143497 0.44 ENSMUST00000008016.2
inhibitor of DNA binding 3
chr13_+_98263242 0.43 ENSMUST00000022164.8
ENSMUST00000150352.1
ankyrin repeat, family A (RFXANK-like), 2
chr6_+_108213086 0.43 ENSMUST00000032192.6
inositol 1,4,5-trisphosphate receptor 1
chr7_-_141434532 0.42 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr1_+_88070765 0.42 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr9_-_106247730 0.40 ENSMUST00000112524.2
ENSMUST00000074082.6
aminolevulinic acid synthase 1
chr9_-_55919605 0.40 ENSMUST00000037408.8
S phase cyclin A-associated protein in the ER
chr8_+_11840474 0.38 ENSMUST00000033909.7
testis expressed 29
chr13_+_47193942 0.37 ENSMUST00000110111.2
ring finger protein 144B
chrX_+_20364481 0.37 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
retinitis pigmentosa 2 homolog (human)
chr2_-_120970706 0.37 ENSMUST00000028728.5
ubiquitin protein ligase E3 component n-recognin 1
chr11_-_5542177 0.36 ENSMUST00000020776.4
coiled-coil domain containing 117
chr3_+_66219909 0.36 ENSMUST00000029421.5
pentraxin related gene
chr1_-_136131171 0.35 ENSMUST00000146091.3
ENSMUST00000165464.1
ENSMUST00000166747.1
ENSMUST00000134998.1
predicted gene 15850
chr13_+_98263187 0.35 ENSMUST00000091356.3
ENSMUST00000123924.1
ankyrin repeat, family A (RFXANK-like), 2
chr3_+_132634725 0.35 ENSMUST00000163241.1
predicted gene 5549
chr1_+_182409162 0.34 ENSMUST00000117245.1
transformation related protein 53 binding protein 2
chr7_-_41448641 0.34 ENSMUST00000165029.1
vomeronasal 2, receptor 57
chr8_+_33653238 0.33 ENSMUST00000033992.8
glutathione reductase
chr13_+_98263105 0.33 ENSMUST00000150916.1
ankyrin repeat, family A (RFXANK-like), 2
chr6_+_96115249 0.33 ENSMUST00000075080.5
family with sequence similarity 19, member A1
chr11_+_60479915 0.33 ENSMUST00000126522.1
myosin XV
chr11_-_115628125 0.32 ENSMUST00000155709.1
ENSMUST00000021089.4
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr4_-_138367966 0.32 ENSMUST00000030535.3
cytidine deaminase
chr2_-_26516620 0.31 ENSMUST00000132820.1
notch 1
chr5_-_20951769 0.30 ENSMUST00000036489.5
round spermatid basic protein 1-like
chr14_+_54883377 0.30 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
BCL2-like 2
predicted gene 20521
chr16_-_23225334 0.30 ENSMUST00000055369.4
cDNA sequence BC106179
chr7_-_140507318 0.29 ENSMUST00000064392.6
olfactory receptor 536
chr6_+_40471352 0.28 ENSMUST00000114779.2
ENSMUST00000031971.6
ENSMUST00000121360.1
ENSMUST00000117411.1
ENSMUST00000117830.1
single-stranded DNA binding protein 1
chr16_-_56024628 0.28 ENSMUST00000119981.1
ENSMUST00000096021.3
PEST proteolytic signal containing nuclear protein
chr11_-_115628260 0.28 ENSMUST00000178003.1
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr3_-_142881942 0.28 ENSMUST00000043812.8
protein kinase N2
chr2_+_166805506 0.27 ENSMUST00000099078.3
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr5_-_38502079 0.27 ENSMUST00000147664.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr18_+_69346143 0.27 ENSMUST00000114980.1
transcription factor 4
chr6_-_55681257 0.26 ENSMUST00000044767.8
neurogenic differentiation 6
chr12_-_20900867 0.26 ENSMUST00000079237.5
zinc finger protein 125
chr19_-_7483212 0.26 ENSMUST00000088169.5
reticulon 3
chr3_-_88458876 0.25 ENSMUST00000147200.1
ENSMUST00000169222.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr9_+_53771499 0.25 ENSMUST00000048670.8
solute carrier family 35, member F2
chr1_+_106980979 0.25 ENSMUST00000027564.1
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
chr18_-_46280820 0.24 ENSMUST00000025354.3
protein geranylgeranyltransferase type I, beta subunit
chr12_+_59066908 0.24 ENSMUST00000021381.4
pinin
chr1_+_58646608 0.24 ENSMUST00000081455.4
predicted gene 10068
chr9_-_71168657 0.24 ENSMUST00000113570.1
aquaporin 9
chr17_-_13761441 0.23 ENSMUST00000127032.1
t-complex-associated testis expressed 2
chr13_-_35027077 0.23 ENSMUST00000170538.1
ENSMUST00000163280.1
enoyl-Coenzyme A delta isomerase 2
chr13_-_99344652 0.21 ENSMUST00000022153.6
pentatricopeptide repeat domain 2
chr3_-_144849301 0.21 ENSMUST00000159989.1
chloride channel calcium activated 4
chr18_+_36744656 0.21 ENSMUST00000007042.5
IK cytokine
chr16_+_75592844 0.21 ENSMUST00000114249.1
ENSMUST00000046378.7
ENSMUST00000114253.1
RNA binding motif protein 11
chr7_-_46795881 0.20 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hermansky-Pudlak syndrome 5 homolog (human)
chr15_-_100424092 0.20 ENSMUST00000154676.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_-_102697710 0.19 ENSMUST00000164506.2
ENSMUST00000092569.6
coiled-coil domain containing 43
chr1_+_161395409 0.19 ENSMUST00000028024.4
tumor necrosis factor (ligand) superfamily, member 4
chr6_+_42286709 0.19 ENSMUST00000163936.1
chloride channel 1
chrX_+_73064787 0.19 ENSMUST00000060418.6
paraneoplastic antigen MA3
chr17_+_8283762 0.18 ENSMUST00000155364.1
ENSMUST00000046754.8
ENSMUST00000124023.1
mitochondrial pyruvate carrier 1
chr5_-_143138200 0.18 ENSMUST00000164536.2
olfactory receptor 718, pseudogene 1
chrX_-_7319291 0.18 ENSMUST00000128319.1
chloride channel 5
chr3_-_88459047 0.18 ENSMUST00000165898.1
ENSMUST00000127436.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_-_45408955 0.17 ENSMUST00000163230.1
CD200 antigen
chr6_+_42286676 0.17 ENSMUST00000031894.6
chloride channel 1
chr10_-_120979327 0.17 ENSMUST00000119944.1
ENSMUST00000119093.1
LEM domain containing 3
chr3_+_79885930 0.17 ENSMUST00000029567.8
family with sequence similarity 198, member B
chr11_+_55213783 0.17 ENSMUST00000108867.1
solute carrier family 36 (proton/amino acid symporter), member 1
chr7_+_126649297 0.16 ENSMUST00000032956.8
coiled-coil domain containing 101
chr5_+_3543812 0.16 ENSMUST00000115527.3
family with sequence similarity 133, member B
chr12_-_23780265 0.15 ENSMUST00000072014.4
predicted gene 10330
chr13_+_58281183 0.15 ENSMUST00000180882.1
ENSMUST00000180452.1
predicted gene, 26555
chr3_+_89177463 0.14 ENSMUST00000029684.8
ENSMUST00000120697.1
ENSMUST00000098941.4
secretory carrier membrane protein 3
chr11_-_102407315 0.14 ENSMUST00000149777.1
ENSMUST00000154001.1
solute carrier family 25, member 39
chr6_-_87809757 0.13 ENSMUST00000032134.7
RAB43, member RAS oncogene family
chr7_+_140247267 0.13 ENSMUST00000059882.6
RIKEN cDNA 5830411N06 gene
chr11_+_77216180 0.12 ENSMUST00000037912.5
ENSMUST00000156488.1
slingshot homolog 2 (Drosophila)
chr3_+_145576196 0.12 ENSMUST00000098534.4
zinc finger, HIT type 6
chr7_-_126649556 0.12 ENSMUST00000084587.1
RIKEN cDNA 2510046G10 gene
chr4_+_39450268 0.12 ENSMUST00000029955.4
RIKEN cDNA 1700009N14 gene
chr3_+_126597299 0.11 ENSMUST00000106400.2
ENSMUST00000106401.1
calcium/calmodulin-dependent protein kinase II, delta
chr1_+_72307413 0.11 ENSMUST00000027379.8
X-ray repair complementing defective repair in Chinese hamster cells 5
chr9_+_40873981 0.11 ENSMUST00000067375.3
brain specific homeobox
chr2_-_147085445 0.11 ENSMUST00000067020.2
NK2 homeobox 4
chr16_-_74411776 0.11 ENSMUST00000116586.2
roundabout homolog 2 (Drosophila)
chr7_+_43634718 0.10 ENSMUST00000032663.8
carcinoembryonic antigen-related cell adhesion molecule 18
chr13_-_66852017 0.10 ENSMUST00000059329.6
predicted gene, 17449
chr7_-_46795661 0.09 ENSMUST00000123725.1
Hermansky-Pudlak syndrome 5 homolog (human)
chr2_+_74711911 0.09 ENSMUST00000111983.2
homeobox D3
chr4_+_108328136 0.09 ENSMUST00000131656.1
Sel1 repeat containing 1
chr4_+_109235262 0.08 ENSMUST00000106631.2
calreticulin 4
chr10_-_67912620 0.08 ENSMUST00000064656.7
zinc finger protein 365
chrX_+_133908441 0.08 ENSMUST00000113304.1
sushi-repeat-containing protein, X-linked 2
chr9_-_14782964 0.08 ENSMUST00000034406.3
ankyrin repeat domain 49
chr17_+_19362135 0.08 ENSMUST00000176107.1
vomeronasal 2, receptor 99
chr3_+_126597415 0.07 ENSMUST00000066452.7
ENSMUST00000171289.1
ENSMUST00000106399.1
calcium/calmodulin-dependent protein kinase II, delta
chr4_+_102741287 0.07 ENSMUST00000097948.2
SH3-domain GRB2-like (endophilin) interacting protein 1
chr6_+_40325471 0.07 ENSMUST00000031977.8
acylglycerol kinase
chr11_-_4441082 0.06 ENSMUST00000109949.1
ENSMUST00000130174.1
HORMA domain containing 2
chr9_-_110946158 0.06 ENSMUST00000035075.8
teratocarcinoma-derived growth factor 1
chr12_-_27160311 0.05 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
predicted gene 9866
chr13_-_19732929 0.05 ENSMUST00000151029.1
RIKEN cDNA A530099J19 gene
chr11_+_59306920 0.05 ENSMUST00000000128.3
ENSMUST00000108783.3
wingless-type MMTV integration site 9A
chr8_+_40307458 0.05 ENSMUST00000068999.7
mitochondrial calcium uptake family, member 3
chr18_-_43393346 0.04 ENSMUST00000025379.7
dihydropyrimidinase-like 3
chr8_+_105225145 0.04 ENSMUST00000034361.3
RIKEN cDNA D230025D16 gene
chr7_+_125318334 0.04 ENSMUST00000060220.1
RIKEN cDNA 4930533L02 gene
chr16_+_87354185 0.04 ENSMUST00000054442.4
ENSMUST00000118310.1
ENSMUST00000120284.1
ENSMUST00000118115.1
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr17_-_6477102 0.03 ENSMUST00000167717.2
transmembrane protein 181B, pseudogene
chr15_+_100423193 0.03 ENSMUST00000148928.1
predicted gene 5475
chr12_-_27160498 0.03 ENSMUST00000182592.1
predicted gene 9866
chr5_+_73651376 0.02 ENSMUST00000071077.7
ENSMUST00000178631.1
ENSMUST00000041422.8
spermatogenesis associated 18
chr11_-_65159890 0.01 ENSMUST00000020855.3
ENSMUST00000108696.1
RIKEN cDNA 1700086D15 gene
chr11_+_75732869 0.01 ENSMUST00000067664.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr18_+_37333853 0.01 ENSMUST00000061717.2
protocadherin beta 6
chr14_-_55671873 0.00 ENSMUST00000163750.1
ENSMUST00000010520.8
neural precursor cell expressed, developmentally down-regulated gene 8
chr11_+_62458414 0.00 ENSMUST00000014389.5
phosphatidylinositol glycan anchor biosynthesis, class L

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa11_Hoxc12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.3 1.1 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.2 1.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 0.9 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.2 1.3 GO:0030242 pexophagy(GO:0030242)
0.2 0.5 GO:0048338 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.2 0.5 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.6 GO:0045425 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.6 GO:0015744 succinate transport(GO:0015744)
0.1 1.3 GO:0030035 microspike assembly(GO:0030035)
0.1 4.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.9 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.4 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.3 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.6 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.7 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 1.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.5 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.4 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.3 GO:0061344 atrioventricular node development(GO:0003162) coronary vein morphogenesis(GO:0003169) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of cell adhesion involved in heart morphogenesis(GO:0061344) positive regulation of ephrin receptor signaling pathway(GO:1901189) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.2 GO:0035709 defense response to nematode(GO:0002215) memory T cell activation(GO:0035709) positive regulation of memory T cell differentiation(GO:0043382) negative regulation of T-helper 1 cell differentiation(GO:0045626) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.2 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.6 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.8 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.7 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.9 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.5 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.5 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 1.0 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0021542 dentate gyrus development(GO:0021542)
0.0 1.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.5 GO:0006378 mRNA polyadenylation(GO:0006378)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031417 NatC complex(GO:0031417)
0.3 0.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.1 GO:1990393 3M complex(GO:1990393)
0.2 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 1.0 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0005771 multivesicular body(GO:0005771)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 1.3 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3 1.0 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 1.0 GO:0008940 nitrate reductase activity(GO:0008940)
0.2 1.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 0.7 GO:0032190 acrosin binding(GO:0032190)
0.2 1.8 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.2 0.6 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 0.6 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.2 1.1 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 0.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.8 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.6 GO:0019767 IgE receptor activity(GO:0019767)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.5 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.5 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0015100 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0070698 nodal binding(GO:0038100) type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism