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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hoxa9_Hoxb9

Z-value: 1.01

Motif logo

Transcription factors associated with Hoxa9_Hoxb9

Gene Symbol Gene ID Gene Info
ENSMUSG00000038227.9 homeobox A9
ENSMUSG00000020875.8 homeobox B9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb9mm10_v2_chr11_+_96271453_962715230.134.5e-01Click!
Hoxa9mm10_v2_chr6_-_52226165_52226196-0.067.2e-01Click!

Activity profile of Hoxa9_Hoxb9 motif

Sorted Z-values of Hoxa9_Hoxb9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_45069137 2.55 ENSMUST00000067984.7
melatonin receptor 1A
chr18_+_20247340 1.94 ENSMUST00000054128.6
desmoglein 1 gamma
chr17_-_43502773 1.93 ENSMUST00000024707.8
ENSMUST00000117137.1
meprin 1 alpha
chr1_+_88211956 1.58 ENSMUST00000073049.6
UDP glucuronosyltransferase 1 family, polypeptide A1
chr8_+_45069374 1.51 ENSMUST00000130141.1
melatonin receptor 1A
chr2_+_58755177 1.37 ENSMUST00000102755.3
uridine phosphorylase 2
chr2_+_58754910 1.26 ENSMUST00000059102.6
uridine phosphorylase 2
chr3_+_138313279 0.94 ENSMUST00000013455.6
ENSMUST00000106247.1
alcohol dehydrogenase 6A (class V)
chr11_+_67078293 0.77 ENSMUST00000108689.1
ENSMUST00000165221.1
ENSMUST00000007301.7
myosin, heavy polypeptide 3, skeletal muscle, embryonic
chr6_+_49822710 0.75 ENSMUST00000031843.6
neuropeptide Y
chr7_-_141434532 0.75 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr18_+_20310738 0.74 ENSMUST00000077146.3
desmoglein 1 alpha
chr16_+_10812915 0.73 ENSMUST00000115822.1
predicted gene 11172
chr2_+_163506808 0.71 ENSMUST00000143911.1
hepatic nuclear factor 4, alpha
chr1_-_66945361 0.71 ENSMUST00000160100.1
myosin, light polypeptide 1
chr7_-_142661858 0.71 ENSMUST00000145896.2
insulin-like growth factor 2
chr18_+_20376723 0.66 ENSMUST00000076737.6
desmoglein 1 beta
chr4_+_42668043 0.64 ENSMUST00000178177.1
predicted gene 9969
chr6_+_115422040 0.62 ENSMUST00000000450.3
peroxisome proliferator activated receptor gamma
chr13_-_23914998 0.61 ENSMUST00000021769.8
ENSMUST00000110407.2
solute carrier family 17 (sodium phosphate), member 4
chr17_-_91092715 0.61 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
neurexin I
chr7_-_45870928 0.58 ENSMUST00000146672.1
glutamate receptor, ionotropic, NMDA2D (epsilon 4)
chr4_+_42170845 0.57 ENSMUST00000179965.1
RIKEN cDNA 1700045I11 gene
chr14_-_70323783 0.55 ENSMUST00000151011.1
solute carrier family 39 (zinc transporter), member 14
chr17_-_34862473 0.53 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr3_+_118562129 0.51 ENSMUST00000039177.7
dihydropyrimidine dehydrogenase
chr3_+_138415484 0.51 ENSMUST00000161312.1
ENSMUST00000013458.8
alcohol dehydrogenase 4 (class II), pi polypeptide
chr15_+_25773985 0.50 ENSMUST00000125667.1
myosin X
chr3_-_113574242 0.49 ENSMUST00000142505.2
amylase 1, salivary
chr17_-_34862122 0.49 ENSMUST00000154526.1
complement factor B
chr5_+_145204523 0.49 ENSMUST00000085671.3
ENSMUST00000031601.7
zinc finger with KRAB and SCAN domains 5
chr8_-_79248537 0.48 ENSMUST00000034109.4
RIKEN cDNA 1700011L22 gene
chr15_-_41869703 0.48 ENSMUST00000054742.5
actin-binding Rho activating protein
chr8_+_4134733 0.47 ENSMUST00000130372.1
CD209g antigen
chr5_+_137787769 0.45 ENSMUST00000035852.7
zinc finger, CW type with PWWP domain 1
chr4_-_49549523 0.45 ENSMUST00000029987.9
aldolase B, fructose-bisphosphate
chr11_+_67171095 0.45 ENSMUST00000018641.7
myosin, heavy polypeptide 2, skeletal muscle, adult
chr1_+_194619815 0.45 ENSMUST00000027952.5
plexin A2
chr18_+_37400845 0.45 ENSMUST00000057228.1
protocadherin beta 9
chr11_+_67171027 0.44 ENSMUST00000170159.1
myosin, heavy polypeptide 2, skeletal muscle, adult
chr17_-_15826521 0.43 ENSMUST00000170578.1
RGM domain family, member B
chr9_+_43310763 0.42 ENSMUST00000034511.5
tripartite motif-containing 29
chr3_+_98280427 0.42 ENSMUST00000090746.2
ENSMUST00000120541.1
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
chr13_+_93674403 0.40 ENSMUST00000048001.6
dimethylglycine dehydrogenase precursor
chr15_+_81936911 0.37 ENSMUST00000135663.1
cold shock domain containing C2, RNA binding
chr7_+_70388305 0.37 ENSMUST00000080024.5
RIKEN cDNA B130024G19 gene
chr2_-_80447625 0.34 ENSMUST00000028389.3
frizzled-related protein
chr14_-_47189406 0.34 ENSMUST00000089959.6
GTP cyclohydrolase 1
chr8_-_4105764 0.34 ENSMUST00000138439.1
ENSMUST00000145007.1
CD209f antigen
chr19_-_56548013 0.34 ENSMUST00000182059.1
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr18_+_12599894 0.33 ENSMUST00000169401.1
tetratricopeptide repeat domain 39C
chr6_-_139501907 0.33 ENSMUST00000170650.1
RERG/RAS-like
chr2_-_67433181 0.32 ENSMUST00000180773.1
predicted gene, 26727
chr9_+_7571396 0.32 ENSMUST00000120900.1
ENSMUST00000093896.3
ENSMUST00000151853.1
ENSMUST00000152878.1
matrix metallopeptidase 27
chr2_+_80315461 0.32 ENSMUST00000028392.7
DnaJ (Hsp40) homolog, subfamily C, member 10
chr11_-_99244058 0.31 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr9_+_45055166 0.30 ENSMUST00000114664.1
ENSMUST00000093856.3
myelin protein zero-like 3
chr6_-_24168083 0.30 ENSMUST00000031713.8
solute carrier family 13 (sodium/sulfate symporters), member 1
chr14_+_55971428 0.30 ENSMUST00000089555.2
chymase 2, mast cell
chr1_-_153844130 0.29 ENSMUST00000124558.3
regulator of G-protein signaling like 1
chr7_+_28277706 0.29 ENSMUST00000094651.2
EP300 interacting inhibitor of differentiation 2B
chr14_-_54282925 0.29 ENSMUST00000059996.4
olfactory receptor 49
chr15_-_101573883 0.28 ENSMUST00000042957.5
keratin 75
chrX_+_139563316 0.28 ENSMUST00000113027.1
ring finger protein 128
chr10_+_3872667 0.28 ENSMUST00000136671.1
ENSMUST00000042438.6
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr10_+_111506286 0.27 ENSMUST00000164773.1
pleckstrin homology-like domain, family A, member 1
chr14_-_57058030 0.27 ENSMUST00000061614.6
gap junction protein, alpha 3
chr5_-_139814231 0.27 ENSMUST00000044002.4
transmembrane protein 184a
chr3_+_108653931 0.25 ENSMUST00000029483.8
ENSMUST00000124384.1
chloride channel CLIC-like 1
chr12_-_113361232 0.25 ENSMUST00000103423.1
Immunoglobulin heavy constant gamma 3
chr3_+_138217814 0.25 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_+_108591279 0.25 ENSMUST00000051145.8
ENSMUST00000139626.1
WD repeat domain 47
chr6_+_79818031 0.23 ENSMUST00000179797.1
predicted gene, 20594
chr17_-_45572495 0.23 ENSMUST00000130406.1
heat shock protein 90 alpha (cytosolic), class B member 1
chr1_-_75232093 0.22 ENSMUST00000180101.1
RIKEN cDNA A630095N17 gene
chr2_-_33087169 0.22 ENSMUST00000102810.3
GTPase activating RANGAP domain-like 3
chr6_-_143947061 0.22 ENSMUST00000124233.1
SRY-box containing gene 5
chr2_-_17390953 0.21 ENSMUST00000177966.1
nebulette
chr7_-_101864093 0.20 ENSMUST00000106981.1
folate receptor 1 (adult)
chr19_-_57197435 0.19 ENSMUST00000111550.1
actin-binding LIM protein 1
chr18_+_37655891 0.19 ENSMUST00000097608.2
RIKEN cDNA 3222401L13 gene
chr15_+_11000716 0.18 ENSMUST00000117100.1
ENSMUST00000022851.7
solute carrier family 45, member 2
chr9_+_92309362 0.18 ENSMUST00000098477.1
ENSMUST00000150594.1
RIKEN cDNA 1700057G04 gene
chr11_-_109298066 0.18 ENSMUST00000106706.1
regulator of G-protein signaling 9
chr7_-_101870683 0.17 ENSMUST00000106986.2
ENSMUST00000106985.1
folate receptor 1 (adult)
chr19_-_57197377 0.17 ENSMUST00000111546.1
actin-binding LIM protein 1
chr11_-_100050542 0.17 ENSMUST00000007318.1
keratin 31
chr18_-_31317043 0.17 ENSMUST00000139924.1
ENSMUST00000153060.1
Ras-like without CAAX 2
chr7_-_135528645 0.16 ENSMUST00000053716.7
clarin 3
chrX_-_145348932 0.16 ENSMUST00000040084.9
ENSMUST00000123443.1
lipoma HMGIC fusion partner-like 1
chr12_+_112620030 0.16 ENSMUST00000180015.1
ENSMUST00000021726.6
adenylosuccinate synthetase like 1
chr1_-_163289214 0.16 ENSMUST00000183691.1
paired related homeobox 1
chr19_+_33822908 0.15 ENSMUST00000042061.6
predicted pseudogene 5519
chr3_+_138065052 0.15 ENSMUST00000163080.2
RIKEN cDNA 1110002E22 gene
chr2_+_147364989 0.15 ENSMUST00000109968.2
paired box gene 1
chr6_-_124965207 0.15 ENSMUST00000148485.1
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr3_+_57425314 0.15 ENSMUST00000029377.7
transmembrane 4 superfamily member 4
chr3_+_66985947 0.14 ENSMUST00000161726.1
ENSMUST00000160504.1
arginine/serine-rich coiled-coil 1
chr11_-_100105626 0.14 ENSMUST00000107416.2
keratin 36
chrY_-_9132561 0.14 ENSMUST00000171947.2
predicted gene, 21292
chr3_+_83026147 0.14 ENSMUST00000166581.1
ENSMUST00000029630.9
fibrinogen alpha chain
chr11_-_83530505 0.14 ENSMUST00000035938.2
chemokine (C-C motif) ligand 5
chr8_+_27042555 0.14 ENSMUST00000033875.8
ENSMUST00000098851.4
proline synthetase co-transcribed
chr3_+_66985647 0.14 ENSMUST00000162362.1
ENSMUST00000065074.7
arginine/serine-rich coiled-coil 1
chr17_-_29007925 0.13 ENSMUST00000009138.5
ENSMUST00000119274.1
serine/threonine kinase 38
chr5_-_107869153 0.13 ENSMUST00000128723.1
ENSMUST00000124034.1
ecotropic viral integration site 5
chr4_+_108459389 0.13 ENSMUST00000106673.1
ENSMUST00000043368.5
zinc finger, CCHC domain containing 11
chr7_-_101870711 0.13 ENSMUST00000151706.1
folate receptor 1 (adult)
chr10_+_17796256 0.12 ENSMUST00000037964.6
taxilin beta
chr3_+_132634725 0.12 ENSMUST00000163241.1
predicted gene 5549
chr13_-_91388079 0.12 ENSMUST00000181054.1
RIKEN cDNA A830009L08 gene
chr7_-_45062393 0.12 ENSMUST00000129101.1
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr9_+_121366958 0.12 ENSMUST00000045903.6
trafficking protein, kinesin binding 1
chr16_+_91225550 0.12 ENSMUST00000035608.8
oligodendrocyte transcription factor 2
chr5_-_77095225 0.11 ENSMUST00000120827.2
ENSMUST00000113453.2
HOP homeobox
chr2_-_27463994 0.11 ENSMUST00000164296.1
bromodomain containing 3
chr7_+_44896077 0.11 ENSMUST00000071207.7
ENSMUST00000166849.1
ENSMUST00000168712.1
ENSMUST00000168389.1
fuzzy homolog (Drosophila)
chr3_+_66985680 0.11 ENSMUST00000065047.6
arginine/serine-rich coiled-coil 1
chr19_-_57197496 0.11 ENSMUST00000111544.1
actin-binding LIM protein 1
chr4_+_115737754 0.11 ENSMUST00000106522.2
EF-hand calcium binding domain 14
chr4_+_44012638 0.11 ENSMUST00000107847.3
ENSMUST00000170241.1
clathrin, light polypeptide (Lca)
chr17_+_38145393 0.11 ENSMUST00000173610.1
olfactory receptor 133
chr16_-_52454074 0.11 ENSMUST00000023312.7
activated leukocyte cell adhesion molecule
chr3_+_138374121 0.10 ENSMUST00000171054.1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr8_+_9977707 0.10 ENSMUST00000139793.1
ENSMUST00000048216.5
abhydrolase domain containing 13
chr12_+_105159690 0.10 ENSMUST00000085043.5
T cell leukemia/lymphoma 1B, 1
chr4_+_44012661 0.10 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
clathrin, light polypeptide (Lca)
chr2_-_31845925 0.10 ENSMUST00000028188.7
fibrinogen C domain containing 1
chr1_-_97761538 0.09 ENSMUST00000171129.1
diphosphoinositol pentakisphosphate kinase 2
chr5_-_26089291 0.08 ENSMUST00000094946.4
predicted gene 10471
chr6_-_143947092 0.08 ENSMUST00000144289.1
ENSMUST00000111748.1
SRY-box containing gene 5
chr7_-_101870778 0.08 ENSMUST00000001882.4
ENSMUST00000126204.1
ENSMUST00000155311.1
ENSMUST00000106983.1
ENSMUST00000123630.1
folate receptor 1 (adult)
chrY_-_3303466 0.08 ENSMUST00000179508.1
predicted gene, 21677
chr15_+_81936753 0.08 ENSMUST00000038757.7
cold shock domain containing C2, RNA binding
chr5_+_26257691 0.08 ENSMUST00000074148.6
predicted gene 7361
chr5_-_26105362 0.07 ENSMUST00000063524.2
RIKEN cDNA 5031410I06 gene
chr10_-_63927434 0.07 ENSMUST00000079279.3
predicted gene 10118
chr7_+_30231884 0.07 ENSMUST00000019882.9
polymerase (RNA) II (DNA directed) polypeptide I
chr6_-_97148908 0.07 ENSMUST00000142116.1
ENSMUST00000113387.1
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr7_-_22229484 0.07 ENSMUST00000167253.1
predicted gene 8453
chrY_+_3774805 0.07 ENSMUST00000180202.1
predicted gene 3376
chrY_-_3407067 0.07 ENSMUST00000180310.1
predicted gene, 21708
chr2_-_177267036 0.07 ENSMUST00000108963.1
predicted gene 14409
chr1_-_30719961 0.06 ENSMUST00000065469.1
predicted gene 9898
chr3_+_14480692 0.06 ENSMUST00000037321.7
ENSMUST00000120484.1
ENSMUST00000120801.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr11_-_109298090 0.06 ENSMUST00000106704.2
regulator of G-protein signaling 9
chr3_+_66985700 0.06 ENSMUST00000046542.6
ENSMUST00000162693.1
arginine/serine-rich coiled-coil 1
chr8_+_112570043 0.06 ENSMUST00000034225.6
ENSMUST00000118171.1
contactin associated protein-like 4
chr4_+_115737738 0.06 ENSMUST00000106525.2
EF-hand calcium binding domain 14
chr6_+_104492790 0.06 ENSMUST00000161446.1
ENSMUST00000161070.1
ENSMUST00000089215.5
contactin 6
chr2_+_32395896 0.06 ENSMUST00000028162.3
prostaglandin E synthase 2
chr1_-_171240055 0.06 ENSMUST00000131286.1
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr5_-_26004798 0.05 ENSMUST00000168875.1
predicted gene 1979
chr7_-_127449109 0.05 ENSMUST00000053392.4
zinc finger protein 689
chrX_-_134541847 0.05 ENSMUST00000054213.4
translocase of inner mitochondrial membrane 8A1
chr19_-_56548122 0.05 ENSMUST00000026063.5
ENSMUST00000182276.1
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr7_-_20912347 0.05 ENSMUST00000172322.1
vomeronasal 1 receptor 118
chr7_-_22692317 0.05 ENSMUST00000178871.1
predicted gene 8693
chr7_-_23251682 0.05 ENSMUST00000164045.1
predicted gene 4220
chr14_+_20674311 0.05 ENSMUST00000048657.8
Sec24 related gene family, member C (S. cerevisiae)
chr5_-_26039506 0.05 ENSMUST00000079447.2
spermatogenesis associated glutamate (E)-rich protein 4a
chr8_-_33843562 0.05 ENSMUST00000183062.1
RNA binding protein gene with multiple splicing
chrY_+_55733188 0.05 ENSMUST00000177834.1
predicted gene, 21858
chr2_+_28205648 0.05 ENSMUST00000102879.3
ENSMUST00000028177.4
olfactomedin 1
chr7_-_21546090 0.05 ENSMUST00000179390.1
predicted gene 4172
chrY_-_29683370 0.04 ENSMUST00000180373.1
predicted gene, 21679
chr5_-_26121421 0.04 ENSMUST00000088236.3
predicted gene 10220
chr7_-_127448993 0.04 ENSMUST00000106299.1
zinc finger protein 689
chr5_-_62766153 0.04 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_+_71981522 0.04 ENSMUST00000114569.1
fetal and adult testis expressed 1
chr11_+_96194299 0.04 ENSMUST00000062709.3
homeobox B13
chr2_+_22622183 0.03 ENSMUST00000028123.3
glutamic acid decarboxylase 2
chr2_-_45112890 0.03 ENSMUST00000076836.6
zinc finger E-box binding homeobox 2
chr6_+_147042755 0.03 ENSMUST00000036111.7
mitochondrial ribosomal protein S35
chr7_-_20233828 0.03 ENSMUST00000168580.1
predicted gene 4498
chr14_-_33978751 0.03 ENSMUST00000166737.1
zinc finger protein 488
chr10_+_23960494 0.03 ENSMUST00000092660.1
trace amine-associated receptor 4
chr5_+_35388844 0.03 ENSMUST00000087674.3
H6 homeobox 1
chrY_+_2904133 0.03 ENSMUST00000166474.2
predicted gene 10352
chrY_-_68293479 0.02 ENSMUST00000180329.1
predicted gene, 20937
chr4_-_4793275 0.02 ENSMUST00000084949.2
inositol monophosphatase domain containing 1
chr4_+_145670685 0.02 ENSMUST00000105738.2
predicted gene 13242
chr5_-_32746317 0.02 ENSMUST00000135248.1
phosphatidylserine decarboxylase
chr10_-_130429612 0.02 ENSMUST00000171811.2
vomeronasal 2, receptor 85
chr7_-_22028897 0.02 ENSMUST00000179206.1
predicted gene 4179
chr11_+_87566653 0.02 ENSMUST00000060360.5
predicted gene 11492
chr11_+_115403734 0.02 ENSMUST00000153983.1
ENSMUST00000106539.3
ENSMUST00000103036.4
immature colon carcinoma transcript 1
chrY_+_70443305 0.02 ENSMUST00000178934.1
predicted gene, 20888
chr11_-_78386558 0.02 ENSMUST00000108294.1
forkhead box N1
chr17_-_6621267 0.02 ENSMUST00000115772.3
transmembrane protein 181C, pseudogene
chr3_-_95106907 0.02 ENSMUST00000107233.2
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr2_+_125136692 0.02 ENSMUST00000099452.2
cortexin 2
chr18_-_31447383 0.02 ENSMUST00000025110.3
synaptotagmin IV
chr1_+_139422196 0.01 ENSMUST00000039867.7
zinc finger and BTB domain containing 41 homolog
chr1_+_153891646 0.01 ENSMUST00000050660.4
transmembrane epididymal protein 1
chr9_+_75311395 0.01 ENSMUST00000076889.6
guanine nucleotide binding protein (G protein), beta 5
chr5_+_63812447 0.01 ENSMUST00000081747.3
RIKEN cDNA 0610040J01 gene
chr5_-_66514815 0.01 ENSMUST00000161879.1
ENSMUST00000159357.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr3_+_90062781 0.01 ENSMUST00000029551.2
RIKEN cDNA 1700094D03 gene
chr5_-_26022916 0.01 ENSMUST00000072286.6
predicted gene 5862

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa9_Hoxb9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0018879 biphenyl metabolic process(GO:0018879)
0.2 0.7 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.2 4.1 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.2 0.6 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.2 0.8 GO:0006069 ethanol oxidation(GO:0006069)
0.2 0.5 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) thymidine metabolic process(GO:0046104)
0.2 0.6 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.1 0.4 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.1 0.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1 0.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.3 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.1 0.2 GO:1903660 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.3 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.1 0.6 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.8 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.4 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.2 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:2000503 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) diapedesis(GO:0050904) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.8 GO:0032098 regulation of appetite(GO:0032098)
0.0 3.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.0 0.6 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 2.6 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.4 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:0045098 type III intermediate filament(GO:0045098)
0.1 1.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 3.3 GO:0030057 desmosome(GO:0030057)
0.1 0.5 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.2 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0097447 dendritic tree(GO:0097447)
0.0 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.5 2.6 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.3 0.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 0.7 GO:0070540 stearic acid binding(GO:0070540)
0.1 0.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.5 GO:0002054 nucleobase binding(GO:0002054)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.6 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.2 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0002135 CTP binding(GO:0002135)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0019840 isoprenoid binding(GO:0019840)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 4.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis