Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Hoxd10

Z-value: 0.32

Motif logo

logo of

Transcription factors associated with Hoxd10

Gene Symbol Gene ID Gene Info
Hoxd10
ENSMUSG00000050368.3 homeobox D10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd10mm10_v2_chr2_+_74691090_74691090-0.251.4e-01Click!

Activity profile of Hoxd10 motif

Sorted Z-values of Hoxd10 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_109990430 1.51 ENSMUST00000001720.7
ENSMUST00000143741.1
Tat
tyrosine aminotransferase
chr13_+_49582745 0.77 ENSMUST00000065494.7
Omd
osteomodulin
chr17_-_78684262 0.66 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr1_-_130661584 0.65 ENSMUST00000137276.2
C4bp
complement component 4 binding protein
chr5_-_92328068 0.65 ENSMUST00000113093.3
Cxcl9
chemokine (C-X-C motif) ligand 9
chr13_-_71963713 0.59 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr7_+_51880312 0.59 ENSMUST00000145049.1
Gas2
growth arrest specific 2
chr1_-_130661613 0.56 ENSMUST00000027657.7
C4bp
complement component 4 binding protein
chr8_+_46010596 0.49 ENSMUST00000110381.2
Lrp2bp
Lrp2 binding protein
chr15_+_9140527 0.48 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2
chr3_+_138277489 0.47 ENSMUST00000004232.9
Adh1
alcohol dehydrogenase 1 (class I)
chr15_+_25773985 0.45 ENSMUST00000125667.1
Myo10
myosin X
chr15_-_5108469 0.45 ENSMUST00000141020.1
Card6
caspase recruitment domain family, member 6
chr3_+_115080965 0.43 ENSMUST00000051309.8
Olfm3
olfactomedin 3
chr4_+_100478806 0.42 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u
ubiquitin-conjugating enzyme E2U (putative)
chr7_+_30095150 0.39 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260
zinc finger protein 260
chr6_-_92481343 0.34 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chr3_-_75270073 0.32 ENSMUST00000039047.4
Serpini2
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr9_-_90255927 0.32 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr19_+_37436707 0.30 ENSMUST00000128184.1
Hhex
hematopoietically expressed homeobox
chr16_-_23029012 0.28 ENSMUST00000039338.6
Kng2
kininogen 2
chr10_-_24101951 0.28 ENSMUST00000170267.1
Taar8c
trace amine-associated receptor 8C
chr5_+_121777929 0.28 ENSMUST00000160821.1
Atxn2
ataxin 2
chr16_-_23029080 0.28 ENSMUST00000100046.2
Kng2
kininogen 2
chr18_-_75697639 0.27 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr17_+_71204647 0.26 ENSMUST00000126681.1
Lpin2
lipin 2
chr3_+_86084434 0.26 ENSMUST00000107664.2
Sh3d19
SH3 domain protein D19
chr16_-_23029062 0.25 ENSMUST00000115349.2
Kng2
kininogen 2
chr15_+_57912199 0.24 ENSMUST00000022992.6
Tbc1d31
TBC1 domain family, member 31
chr8_-_84773381 0.23 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chrX_-_70365052 0.23 ENSMUST00000101509.2
Ids
iduronate 2-sulfatase
chr15_-_93336800 0.22 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chrX_-_8591816 0.22 ENSMUST00000089374.4
Ssxb3
synovial sarcoma, X member B, breakpoint 3
chr16_-_16560046 0.21 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr10_+_97607166 0.20 ENSMUST00000105286.2
Kera
keratocan
chr4_+_102254993 0.19 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr1_-_59003443 0.18 ENSMUST00000054653.6
Als2cr11
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 (human)
chr16_+_23058250 0.18 ENSMUST00000039492.6
ENSMUST00000023589.8
ENSMUST00000089902.6
Kng1
kininogen 1
chr4_+_19605451 0.18 ENSMUST00000108250.2
Gm12353
predicted gene 12353
chr11_+_67171095 0.18 ENSMUST00000018641.7
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr1_+_107422681 0.17 ENSMUST00000112710.1
ENSMUST00000086690.4
Serpinb7
serine (or cysteine) peptidase inhibitor, clade B, member 7
chr1_+_139501692 0.17 ENSMUST00000027615.5
F13b
coagulation factor XIII, beta subunit
chr2_+_120404757 0.17 ENSMUST00000135074.1
Ganc
glucosidase, alpha; neutral C
chr11_+_67171027 0.16 ENSMUST00000170159.1
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr3_-_14808358 0.15 ENSMUST00000181860.1
ENSMUST00000144327.2
Car1
carbonic anhydrase 1
chr14_+_53831105 0.14 ENSMUST00000103673.4
Trav18
T cell receptor alpha variable 18
chr6_-_23655129 0.13 ENSMUST00000104979.1
Rnf148
ring finger protein 148
chr12_+_76417598 0.12 ENSMUST00000063977.7
Ppp1r36
protein phosphatase 1, regulatory subunit 36
chr10_+_23851454 0.12 ENSMUST00000020190.7
Vnn3
vanin 3
chr3_+_116968267 0.11 ENSMUST00000117592.1
4930455H04Rik
RIKEN cDNA 4930455H04 gene
chr9_+_104569671 0.11 ENSMUST00000057742.8
Cpne4
copine IV
chr4_+_43401232 0.10 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr16_+_25801907 0.09 ENSMUST00000040231.6
ENSMUST00000115306.1
ENSMUST00000115304.1
ENSMUST00000115305.1
Trp63
transformation related protein 63
chr13_+_40917626 0.09 ENSMUST00000067778.6
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr1_+_180111339 0.09 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr7_+_96210107 0.09 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr3_-_123034943 0.09 ENSMUST00000029761.7
Myoz2
myozenin 2
chr6_+_33249085 0.08 ENSMUST00000052266.8
ENSMUST00000090381.4
ENSMUST00000115080.1
Exoc4
exocyst complex component 4
chr14_+_53806497 0.07 ENSMUST00000103672.4
Trav17
T cell receptor alpha variable 17
chr7_-_73541738 0.07 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr18_+_52615908 0.07 ENSMUST00000072666.3
Zfp474
zinc finger protein 474
chrX_+_7762652 0.06 ENSMUST00000077680.3
ENSMUST00000079542.6
ENSMUST00000115679.1
ENSMUST00000137467.1
Tfe3
transcription factor E3
chr3_+_106486009 0.06 ENSMUST00000183271.1
ENSMUST00000061206.3
Dennd2d
DENN/MADD domain containing 2D
chr9_+_95857597 0.05 ENSMUST00000034980.7
Atr
ataxia telangiectasia and Rad3 related
chrX_+_66653003 0.05 ENSMUST00000036043.4
Slitrk2
SLIT and NTRK-like family, member 2
chrY_+_55733188 0.05 ENSMUST00000177834.1
Gm21858
predicted gene, 21858
chr12_+_55089202 0.05 ENSMUST00000021407.10
Srp54a
signal recognition particle 54A
chr4_-_108833608 0.04 ENSMUST00000102742.4
Btf3l4
basic transcription factor 3-like 4
chr9_-_45828618 0.04 ENSMUST00000117194.1
Cep164
centrosomal protein 164
chr6_-_28397999 0.04 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chr2_+_21367532 0.04 ENSMUST00000055946.7
Gpr158
G protein-coupled receptor 158
chr4_-_108833544 0.04 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4
basic transcription factor 3-like 4
chr10_+_69534039 0.03 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr11_-_110168073 0.02 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr10_+_21295979 0.02 ENSMUST00000020153.8
ENSMUST00000092674.6
Hbs1l
Hbs1-like (S. cerevisiae)
chr10_+_128790903 0.02 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr3_-_95282076 0.01 ENSMUST00000015855.7
Prune
prune homolog (Drosophila)
chr17_-_46327949 0.01 ENSMUST00000047970.7
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr6_+_124024758 0.01 ENSMUST00000032238.3
Vmn2r26
vomeronasal 2, receptor 26
chr15_-_103215285 0.00 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5
chromobox 5

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd10

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.6 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.5 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.3 GO:0061010 gall bladder development(GO:0061010)
0.1 0.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0060197 cloacal septation(GO:0060197)
0.0 0.6 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 1.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0060912 cardiac cell fate specification(GO:0060912)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 1.0 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2 0.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway