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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hsf1

Z-value: 0.71

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Transcription factors associated with Hsf1

Gene Symbol Gene ID Gene Info
Hsf1
ENSMUSG00000022556.9 heat shock factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hsf1mm10_v2_chr15_+_76477404_764774610.038.5e-01Click!

Activity profile of Hsf1 motif

Sorted Z-values of Hsf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_149636164 2.05 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr7_+_140845562 1.57 ENSMUST00000035300.5
Scgb1c1
secretoglobin, family 1C, member 1
chr12_-_110696289 1.23 ENSMUST00000021698.6
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr16_-_88751628 1.17 ENSMUST00000053149.2
Krtap13
keratin associated protein 13
chr6_-_128438673 1.17 ENSMUST00000032508.4
Fkbp4
FK506 binding protein 4
chr5_-_149636331 1.12 ENSMUST00000074846.7
ENSMUST00000110498.1
ENSMUST00000127977.1
ENSMUST00000132412.1
Hsph1
heat shock 105kDa/110kDa protein 1
chr12_-_110695860 1.09 ENSMUST00000149189.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr1_+_195017399 1.02 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr12_-_110696248 0.97 ENSMUST00000124156.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr5_+_30281377 0.88 ENSMUST00000101448.3
Drc1
dynein regulatory complex subunit 1
chr19_-_5802640 0.86 ENSMUST00000173523.1
ENSMUST00000173499.1
ENSMUST00000172812.2
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr6_+_128438757 0.81 ENSMUST00000144745.1
Gm10069
predicted gene 10069
chr12_-_110696332 0.79 ENSMUST00000094361.4
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr3_+_79591356 0.78 ENSMUST00000029382.7
Ppid
peptidylprolyl isomerase D (cyclophilin D)
chr4_+_40722461 0.74 ENSMUST00000030118.3
Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr5_-_129787175 0.66 ENSMUST00000031399.6
Psph
phosphoserine phosphatase
chr15_+_62039216 0.65 ENSMUST00000183297.1
Pvt1
plasmacytoma variant translocation 1
chr9_+_18292267 0.64 ENSMUST00000001825.7
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr17_-_56874421 0.63 ENSMUST00000043062.4
Acsbg2
acyl-CoA synthetase bubblegum family member 2
chr5_-_66151903 0.62 ENSMUST00000167950.1
Rbm47
RNA binding motif protein 47
chr5_+_135887988 0.61 ENSMUST00000111155.1
Hspb1
heat shock protein 1
chr18_-_10706688 0.59 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3
abhydrolase domain containing 3
chr10_-_86705485 0.58 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr16_+_88777829 0.57 ENSMUST00000009191.3
Gm5965
predicted gene 5965
chr5_+_135887905 0.57 ENSMUST00000005077.6
Hspb1
heat shock protein 1
chr11_-_106579111 0.56 ENSMUST00000103070.2
Tex2
testis expressed gene 2
chrX_+_42149534 0.56 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr9_-_105495130 0.55 ENSMUST00000038118.7
Atp2c1
ATPase, Ca++-sequestering
chr9_-_99436749 0.54 ENSMUST00000122384.1
Mras
muscle and microspikes RAS
chr5_+_151368683 0.54 ENSMUST00000181114.1
ENSMUST00000181555.1
1700028E10Rik
RIKEN cDNA 1700028E10 gene
chr10_+_86302854 0.53 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr16_+_23107413 0.51 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2
eukaryotic translation initiation factor 4A2
chr16_+_23107754 0.50 ENSMUST00000077605.5
ENSMUST00000115341.3
Eif4a2
eukaryotic translation initiation factor 4A2
chr4_+_40722912 0.49 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr9_+_120110349 0.48 ENSMUST00000035106.5
Slc25a38
solute carrier family 25, member 38
chr6_+_29853746 0.47 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr6_-_51469836 0.44 ENSMUST00000090002.7
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr11_-_116335384 0.43 ENSMUST00000036215.7
Foxj1
forkhead box J1
chr1_+_91250482 0.43 ENSMUST00000171112.1
Ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr9_-_105495037 0.43 ENSMUST00000176190.1
ENSMUST00000163879.2
ENSMUST00000112558.2
ENSMUST00000176390.1
Atp2c1
ATPase, Ca++-sequestering
chr1_+_153874335 0.42 ENSMUST00000055314.3
Gm5531
predicted gene 5531
chr17_+_35470083 0.42 ENSMUST00000174525.1
ENSMUST00000068291.6
H2-Q10
histocompatibility 2, Q region locus 10
chrX_-_74023745 0.41 ENSMUST00000114353.3
ENSMUST00000101458.2
Irak1
interleukin-1 receptor-associated kinase 1
chr8_-_45382198 0.40 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr1_+_179961110 0.40 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa
CDC42 binding protein kinase alpha
chr5_-_123749393 0.39 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
Rsrc2
arginine/serine-rich coiled-coil 2
chr10_+_80826656 0.39 ENSMUST00000060987.8
ENSMUST00000177850.1
ENSMUST00000180036.1
ENSMUST00000179172.1
Oaz1
ornithine decarboxylase antizyme 1
chr19_-_7039987 0.37 ENSMUST00000025918.7
Stip1
stress-induced phosphoprotein 1
chr6_-_31218421 0.37 ENSMUST00000115107.1
AB041803
cDNA sequence AB041803
chr5_-_123749371 0.37 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
Rsrc2
arginine/serine-rich coiled-coil 2
chr13_-_111490111 0.37 ENSMUST00000047627.7
Gpbp1
GC-rich promoter binding protein 1
chr6_+_51470339 0.36 ENSMUST00000094623.3
Cbx3
chromobox 3
chr5_+_29735991 0.36 ENSMUST00000012734.5
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr4_+_148140699 0.35 ENSMUST00000140049.1
ENSMUST00000105707.1
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr6_-_51469869 0.34 ENSMUST00000114459.1
ENSMUST00000069949.6
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr15_-_81399594 0.32 ENSMUST00000023039.8
St13
suppression of tumorigenicity 13
chr5_+_29735940 0.32 ENSMUST00000114839.1
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chrX_+_42149288 0.30 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2
stromal antigen 2
chr13_-_12464925 0.29 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr5_-_143895025 0.29 ENSMUST00000079624.5
ENSMUST00000110717.2
Ankrd61
ankyrin repeat domain 61
chr11_-_48946148 0.29 ENSMUST00000104958.1
Psme2b
protease (prosome, macropain) activator subunit 2B
chr7_+_92561141 0.28 ENSMUST00000032842.6
ENSMUST00000085017.4
Ccdc90b
coiled-coil domain containing 90B
chr9_-_110989611 0.28 ENSMUST00000084922.5
Rtp3
receptor transporter protein 3
chr7_-_89941084 0.28 ENSMUST00000075010.4
ENSMUST00000153470.1
l7Rn6
lethal, Chr 7, Rinchik 6
chr15_-_100403243 0.28 ENSMUST00000124324.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_-_46715676 0.28 ENSMUST00000006956.7
Saa3
serum amyloid A 3
chr12_-_54695813 0.28 ENSMUST00000110713.3
Eapp
E2F-associated phosphoprotein
chr12_+_105784694 0.27 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
Papola
poly (A) polymerase alpha
chr3_-_89402650 0.27 ENSMUST00000168325.1
ENSMUST00000057431.5
Lenep
lens epithelial protein
chr19_-_29812952 0.26 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr7_-_89941196 0.26 ENSMUST00000117354.1
l7Rn6
lethal, Chr 7, Rinchik 6
chr15_-_81400043 0.25 ENSMUST00000172107.1
ENSMUST00000169204.1
ENSMUST00000163382.1
St13
suppression of tumorigenicity 13
chrX_-_140956675 0.25 ENSMUST00000033805.8
ENSMUST00000112978.1
Psmd10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr7_-_19887946 0.25 ENSMUST00000052605.7
Ceacam19
carcinoembryonic antigen-related cell adhesion molecule 19
chr5_+_29735688 0.24 ENSMUST00000008733.8
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chrX_+_71663665 0.23 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr4_+_155601414 0.23 ENSMUST00000105608.2
Slc35e2
solute carrier family 35, member E2
chr5_-_92675253 0.22 ENSMUST00000151180.1
ENSMUST00000150359.1
Ccdc158
coiled-coil domain containing 158
chr16_-_55934797 0.22 ENSMUST00000122280.1
ENSMUST00000121703.2
Cep97
centrosomal protein 97
chr9_+_124102110 0.21 ENSMUST00000168841.1
ENSMUST00000055918.6
Ccr2
chemokine (C-C motif) receptor 2
chr13_+_41655697 0.20 ENSMUST00000067176.8
Gm5082
predicted gene 5082
chrX_-_74023908 0.20 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
Irak1
interleukin-1 receptor-associated kinase 1
chr18_-_36766198 0.20 ENSMUST00000061522.7
Dnd1
dead end homolog 1 (zebrafish)
chr17_+_70929006 0.20 ENSMUST00000092011.6
Gm16519
predicted gene, 16519
chr14_-_76520850 0.19 ENSMUST00000181972.1
4930444M15Rik
RIKEN cDNA 4930444M15 gene
chr10_+_127642975 0.19 ENSMUST00000092074.5
ENSMUST00000120279.1
Stat6
signal transducer and activator of transcription 6
chr4_-_40722307 0.18 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr14_-_48667508 0.18 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr12_-_79172609 0.18 ENSMUST00000055262.6
Vti1b
vesicle transport through interaction with t-SNAREs 1B
chr7_-_119895446 0.17 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr2_+_25180737 0.17 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr5_+_129787390 0.17 ENSMUST00000031402.8
Cct6a
chaperonin containing Tcp1, subunit 6a (zeta)
chr11_-_69878018 0.17 ENSMUST00000178597.1
Tmem95
transmembrane protein 95
chr11_+_6560183 0.17 ENSMUST00000109722.2
Ccm2
cerebral cavernous malformation 2
chr1_-_55088156 0.17 ENSMUST00000127861.1
ENSMUST00000144077.1
Hspd1
heat shock protein 1 (chaperonin)
chr14_-_65833963 0.16 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr16_-_88774201 0.15 ENSMUST00000054223.2
2310057N15Rik
RIKEN cDNA 2310057N15 gene
chr12_-_54695829 0.15 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
Eapp
E2F-associated phosphoprotein
chr5_-_92675125 0.14 ENSMUST00000060930.3
Ccdc158
coiled-coil domain containing 158
chr4_+_155601854 0.14 ENSMUST00000118607.1
Slc35e2
solute carrier family 35, member E2
chr11_+_116843278 0.14 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr12_-_54695885 0.14 ENSMUST00000067272.8
Eapp
E2F-associated phosphoprotein
chr17_+_31564749 0.14 ENSMUST00000175806.1
ENSMUST00000097352.3
Pknox1
Pbx/knotted 1 homeobox
chr5_-_151369172 0.13 ENSMUST00000067770.3
D730045B01Rik
RIKEN cDNA D730045B01 gene
chr16_-_94856682 0.13 ENSMUST00000165538.1
Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
chr11_+_22990519 0.12 ENSMUST00000173867.1
ENSMUST00000020562.4
Cct4
chaperonin containing Tcp1, subunit 4 (delta)
chr19_+_6363719 0.12 ENSMUST00000113489.1
ENSMUST00000113488.1
Sf1
splicing factor 1
chr1_-_55088024 0.11 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr12_-_72236692 0.11 ENSMUST00000021497.9
ENSMUST00000137990.1
Rtn1
reticulon 1
chr5_+_148777950 0.11 ENSMUST00000155504.1
4930505K14Rik
RIKEN cDNA 4930505K14 gene
chr2_+_72297895 0.11 ENSMUST00000144111.1
Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr5_+_92331828 0.10 ENSMUST00000125462.1
ENSMUST00000121096.1
ENSMUST00000113083.2
Art3
ADP-ribosyltransferase 3
chr9_-_80465429 0.10 ENSMUST00000085289.5
ENSMUST00000185068.1
ENSMUST00000113250.3
Impg1
interphotoreceptor matrix proteoglycan 1
chr7_+_49759100 0.10 ENSMUST00000085272.5
Htatip2
HIV-1 tat interactive protein 2, homolog (human)
chr19_+_6363896 0.09 ENSMUST00000113487.1
Sf1
splicing factor 1
chr12_+_88083697 0.09 ENSMUST00000177720.1
Gm16368
predicted pseudogene 16368
chr2_+_19344317 0.09 ENSMUST00000141289.1
4930447M23Rik
RIKEN cDNA 4930447M23 gene
chr5_-_28055440 0.09 ENSMUST00000181503.1
Gm26608
predicted gene, 26608
chr18_+_43764317 0.08 ENSMUST00000043803.6
Scgb3a2
secretoglobin, family 3A, member 2
chr12_+_88027004 0.08 ENSMUST00000178852.1
Gm2056
predicted gene 2056
chr16_-_22265950 0.08 ENSMUST00000161286.1
Tra2b
transformer 2 beta homolog (Drosophila)
chr15_+_28203726 0.08 ENSMUST00000067048.6
Dnah5
dynein, axonemal, heavy chain 5
chr19_+_6363671 0.07 ENSMUST00000131252.1
Sf1
splicing factor 1
chr7_-_35585577 0.07 ENSMUST00000069912.4
Rgs9bp
regulator of G-protein signalling 9 binding protein
chr2_-_92460449 0.07 ENSMUST00000125276.1
Slc35c1
solute carrier family 35, member C1
chr17_+_34417347 0.06 ENSMUST00000142317.1
BC051142
cDNA sequence BC051142
chr11_-_5542177 0.06 ENSMUST00000020776.4
Ccdc117
coiled-coil domain containing 117
chr5_+_92331818 0.05 ENSMUST00000154245.1
Art3
ADP-ribosyltransferase 3
chr15_+_88600280 0.05 ENSMUST00000066949.7
Zdhhc25
zinc finger, DHHC domain containing 25
chr10_-_61383523 0.05 ENSMUST00000020289.8
Pald1
phosphatase domain containing, paladin 1
chr8_+_27023793 0.05 ENSMUST00000033873.7
Erlin2
ER lipid raft associated 2
chr18_+_6332587 0.05 ENSMUST00000097682.2
Rpl27-ps3
ribosomal protein L27, pseudogene 3
chrX_-_140813433 0.04 ENSMUST00000044179.7
Tex13
testis expressed gene 13
chr1_+_66322102 0.03 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr16_-_87495704 0.03 ENSMUST00000176750.1
ENSMUST00000175977.1
Cct8
chaperonin containing Tcp1, subunit 8 (theta)
chr2_+_163694015 0.02 ENSMUST00000109400.2
Pkig
protein kinase inhibitor, gamma
chr5_-_36695969 0.02 ENSMUST00000031091.9
ENSMUST00000140063.1
D5Ertd579e
DNA segment, Chr 5, ERATO Doi 579, expressed
chrX_+_21068406 0.02 ENSMUST00000040437.5
Spaca5
sperm acrosome associated 5
chr7_+_119895836 0.02 ENSMUST00000106518.1
ENSMUST00000054440.3
Lyrm1
LYR motif containing 1
chr5_-_45169564 0.02 ENSMUST00000030975.5
4930435H24Rik
RIKEN cDNA 4930435H24 gene
chr15_-_82690499 0.02 ENSMUST00000100380.3
Cyp2d37-ps
cytochrome P450, family 2, subfamily d, polypeptide 37, pseudogene
chr15_+_81400132 0.02 ENSMUST00000163754.1
ENSMUST00000041609.4
Xpnpep3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr4_+_42949814 0.01 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr16_-_87495823 0.01 ENSMUST00000176041.1
ENSMUST00000026704.7
Cct8
chaperonin containing Tcp1, subunit 8 (theta)
chr11_-_116843449 0.01 ENSMUST00000047616.3
Jmjd6
jumonji domain containing 6
chr7_-_70366735 0.01 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr17_+_25162441 0.01 ENSMUST00000073277.5
ENSMUST00000182621.1
Ccdc154
coiled-coil domain containing 154
chr11_-_5099223 0.00 ENSMUST00000079949.6
Ewsr1
Ewing sarcoma breakpoint region 1
chr15_-_76374926 0.00 ENSMUST00000071119.6
Tssk5
testis-specific serine kinase 5
chr15_-_31601506 0.00 ENSMUST00000161266.1
Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.5 3.2 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.3 0.8 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 1.0 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 0.9 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.2 0.9 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.5 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 1.2 GO:0099640 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) axo-dendritic protein transport(GO:0099640)
0.1 0.5 GO:0036233 glycine import(GO:0036233)
0.1 0.8 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.3 GO:0045041 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.4 GO:0061141 lung ciliated cell differentiation(GO:0061141)
0.1 0.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.2 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.6 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.6 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 0.2 GO:1902567 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.1 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 1.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.6 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.6 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.9 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.3 GO:1903405 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.5 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 GO:0002135 CTP binding(GO:0002135)
0.4 3.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.0 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.2 1.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 0.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 0.6 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 0.6 GO:0032564 dATP binding(GO:0032564)
0.1 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 2.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.1 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.6 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis