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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Lhx3

Z-value: 0.77

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Transcription factors associated with Lhx3

Gene Symbol Gene ID Gene Info
Lhx3
ENSMUSG00000026934.9 LIM homeobox protein 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lhx3mm10_v2_chr2_-_26206535_26206580-0.573.1e-04Click!

Activity profile of Lhx3 motif

Sorted Z-values of Lhx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_60081861 4.55 ENSMUST00000029326.5
Sucnr1
succinate receptor 1
chr19_+_20601958 3.98 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr3_-_67515487 2.21 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1
retinoic acid receptor responder (tazarotene induced) 1
chr18_-_38866702 2.17 ENSMUST00000115582.1
Fgf1
fibroblast growth factor 1
chr6_+_124304646 2.15 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163
CD163 antigen
chr19_-_39649046 1.93 ENSMUST00000067328.6
Cyp2c67
cytochrome P450, family 2, subfamily c, polypeptide 67
chrX_-_143933089 1.89 ENSMUST00000087313.3
Dcx
doublecortin
chrM_+_9452 1.82 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr1_+_21240581 1.62 ENSMUST00000027067.8
Gsta3
glutathione S-transferase, alpha 3
chr1_+_21240597 1.58 ENSMUST00000121676.1
Gsta3
glutathione S-transferase, alpha 3
chr4_+_136143497 1.53 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr2_+_23069210 1.43 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr10_-_24101951 1.43 ENSMUST00000170267.1
Taar8c
trace amine-associated receptor 8C
chr7_-_45103747 1.30 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr10_+_75037291 1.28 ENSMUST00000139384.1
Rab36
RAB36, member RAS oncogene family
chr17_-_36032682 1.25 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chrM_+_14138 1.23 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr6_-_130193112 1.14 ENSMUST00000112032.1
ENSMUST00000071554.2
Klra9
killer cell lectin-like receptor subfamily A, member 9
chr1_+_88055377 1.14 ENSMUST00000138182.1
ENSMUST00000113142.3
Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
chr19_-_39812744 1.13 ENSMUST00000162507.1
ENSMUST00000160476.1
Cyp2c40
cytochrome P450, family 2, subfamily c, polypeptide 40
chr3_+_122419772 1.13 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chrM_+_9870 1.09 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr1_+_88055467 1.06 ENSMUST00000173325.1
Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
chrM_-_14060 1.01 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr6_-_115592571 1.00 ENSMUST00000112957.1
2510049J12Rik
RIKEN cDNA 2510049J12 gene
chr11_-_49113757 0.97 ENSMUST00000060398.1
Olfr1396
olfactory receptor 1396
chr4_+_102589687 0.95 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr11_+_109543694 0.92 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr4_+_104913456 0.92 ENSMUST00000106803.2
ENSMUST00000106804.1
1700024P16Rik
RIKEN cDNA 1700024P16 gene
chr3_+_95318782 0.86 ENSMUST00000139866.1
Cers2
ceramide synthase 2
chr19_-_39886730 0.84 ENSMUST00000168838.1
Cyp2c69
cytochrome P450, family 2, subfamily c, polypeptide 69
chr16_+_11406618 0.83 ENSMUST00000122168.1
Snx29
sorting nexin 29
chrX_-_143933204 0.83 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx
doublecortin
chr11_+_58421103 0.80 ENSMUST00000013797.2
1810065E05Rik
RIKEN cDNA 1810065E05 gene
chr19_+_26623419 0.77 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_138879360 0.77 ENSMUST00000105804.1
Pla2g2e
phospholipase A2, group IIE
chr17_-_34862122 0.75 ENSMUST00000154526.1
Cfb
complement factor B
chr6_+_34780412 0.75 ENSMUST00000115016.1
ENSMUST00000115017.1
Agbl3
ATP/GTP binding protein-like 3
chr3_-_96452306 0.69 ENSMUST00000093126.4
ENSMUST00000098841.3
BC107364
cDNA sequence BC107364
chr17_-_34862473 0.68 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb
complement factor B
chr5_+_96209463 0.68 ENSMUST00000117766.1
Mrpl1
mitochondrial ribosomal protein L1
chr4_-_14621669 0.66 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr5_-_142530041 0.65 ENSMUST00000099400.2
Papolb
poly (A) polymerase beta (testis specific)
chr5_-_3647806 0.65 ENSMUST00000119783.1
ENSMUST00000007559.8
Gatad1
GATA zinc finger domain containing 1
chr5_+_96210115 0.62 ENSMUST00000036437.6
ENSMUST00000121477.1
Mrpl1
mitochondrial ribosomal protein L1
chr14_+_69347587 0.60 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr12_-_56536895 0.60 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr13_-_74482943 0.59 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr1_-_24612700 0.58 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr7_-_101581161 0.56 ENSMUST00000063920.2
Art2b
ADP-ribosyltransferase 2b
chr16_-_64771146 0.53 ENSMUST00000076991.6
4930453N24Rik
RIKEN cDNA 4930453N24 gene
chr14_-_48665098 0.53 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr3_+_151437887 0.51 ENSMUST00000046977.7
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr11_-_99374895 0.50 ENSMUST00000006963.2
Krt28
keratin 28
chr11_-_4095344 0.49 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr7_-_37772868 0.49 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr9_+_120929216 0.49 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chr12_-_84617326 0.48 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr11_-_84069179 0.47 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr11_-_100088226 0.47 ENSMUST00000107419.1
Krt32
keratin 32
chr2_+_82053222 0.46 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr2_+_125136692 0.45 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr3_-_57294880 0.45 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr13_+_19342154 0.44 ENSMUST00000103566.3
Tcrg-C4
T cell receptor gamma, constant 4
chr6_+_96115249 0.43 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr11_+_76902152 0.43 ENSMUST00000102495.1
Tmigd1
transmembrane and immunoglobulin domain containing 1
chr14_+_51411001 0.42 ENSMUST00000022438.5
ENSMUST00000163019.1
ENSMUST00000159674.1
Vmn2r88
vomeronasal 2, receptor 88
chr4_+_145670685 0.42 ENSMUST00000105738.2
Gm13242
predicted gene 13242
chr11_+_59306920 0.40 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a
wingless-type MMTV integration site 9A
chr15_-_103565069 0.39 ENSMUST00000023134.3
Glycam1
glycosylation dependent cell adhesion molecule 1
chr5_-_51553896 0.39 ENSMUST00000132734.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr8_-_109251698 0.36 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr1_+_88306731 0.35 ENSMUST00000040210.7
Trpm8
transient receptor potential cation channel, subfamily M, member 8
chr10_-_53647080 0.34 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chrX_+_160768013 0.33 ENSMUST00000033650.7
Rs1
retinoschisis (X-linked, juvenile) 1 (human)
chr4_-_14621494 0.33 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr3_-_116712644 0.32 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr10_+_36506814 0.32 ENSMUST00000167191.1
ENSMUST00000058738.4
Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr11_+_115334731 0.31 ENSMUST00000106543.1
ENSMUST00000019006.4
Otop3
otopetrin 3
chr17_+_45734506 0.31 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr10_-_33624587 0.31 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2
clavesin 2
chr5_+_87666200 0.30 ENSMUST00000094641.4
Csn1s1
casein alpha s1
chr5_-_104077608 0.29 ENSMUST00000164471.1
ENSMUST00000178967.1
Gm17660
predicted gene, 17660
chr5_-_62766153 0.29 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr18_+_37477768 0.28 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr10_+_75037066 0.27 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36
RAB36, member RAS oncogene family
chrX_+_66653003 0.26 ENSMUST00000036043.4
Slitrk2
SLIT and NTRK-like family, member 2
chr14_-_62984502 0.25 ENSMUST00000100493.2
Defb48
defensin beta 48
chr9_+_18409094 0.25 ENSMUST00000098973.2
Ubtfl1
upstream binding transcription factor, RNA polymerase I-like 1
chr10_+_102158858 0.25 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr14_-_96519067 0.24 ENSMUST00000022666.7
Klhl1
kelch-like 1
chr4_+_145868794 0.24 ENSMUST00000123460.1
Gm13235
predicted gene 13235
chr11_-_89639631 0.22 ENSMUST00000128717.1
Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr6_+_37870786 0.22 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24
tripartite motif-containing 24
chr5_+_20702129 0.22 ENSMUST00000101556.4
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_+_105789869 0.22 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr15_-_58364148 0.22 ENSMUST00000068515.7
Anxa13
annexin A13
chr1_+_177444653 0.21 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr10_+_116964707 0.21 ENSMUST00000176050.1
ENSMUST00000176455.1
D630029K05Rik
RIKEN cDNA D630029K05 gene
chr3_-_20367124 0.21 ENSMUST00000163776.2
ENSMUST00000068316.7
Agtr1b
angiotensin II receptor, type 1b
chr1_-_82291370 0.21 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr4_+_145514884 0.21 ENSMUST00000105741.1
Gm13225
predicted gene 13225
chr17_+_69439326 0.19 ENSMUST00000169935.1
A330050F15Rik
RIKEN cDNA A330050F15 gene
chr3_+_14480692 0.19 ENSMUST00000037321.7
ENSMUST00000120484.1
ENSMUST00000120801.1
Slc7a12
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr18_+_57468478 0.18 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr3_+_66985647 0.18 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1
arginine/serine-rich coiled-coil 1
chr2_+_181991226 0.17 ENSMUST00000071760.6
Gm14496
predicted gene 14496
chr3_-_64565298 0.17 ENSMUST00000176481.1
Vmn2r6
vomeronasal 2, receptor 6
chr8_-_21906412 0.17 ENSMUST00000051965.4
Defb11
defensin beta 11
chr4_+_146971976 0.16 ENSMUST00000146688.2
Gm13150
predicted gene 13150
chr8_+_21839926 0.16 ENSMUST00000006745.3
Defb2
defensin beta 2
chr10_-_64090241 0.16 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr4_+_145510759 0.15 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225
predicted gene 13225
chr10_+_102159000 0.15 ENSMUST00000020039.6
Mgat4c
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_+_118961578 0.15 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr3_+_135348029 0.15 ENSMUST00000159658.1
ENSMUST00000078568.5
ENSMUST00000160460.1
Slc9b1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr14_-_118735143 0.15 ENSMUST00000184172.1
RP24-241I19.1
RP24-241I19.1
chr4_+_147492417 0.14 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr1_-_158356258 0.13 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr11_-_24075054 0.12 ENSMUST00000068360.1
A830031A19Rik
RIKEN cDNA A830031A19 gene
chr10_+_116966274 0.12 ENSMUST00000033651.3
D630029K05Rik
RIKEN cDNA D630029K05 gene
chr5_-_62765618 0.11 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_67238017 0.11 ENSMUST00000018632.4
Myh4
myosin, heavy polypeptide 4, skeletal muscle
chr2_-_89024099 0.08 ENSMUST00000099799.2
Olfr1217
olfactory receptor 1217
chrX_-_100625901 0.07 ENSMUST00000059099.6
Pdzd11
PDZ domain containing 11
chr4_+_146097312 0.06 ENSMUST00000105730.1
ENSMUST00000091878.5
Gm13051
predicted gene 13051
chr4_-_147702553 0.05 ENSMUST00000117638.1
Zfp534
zinc finger protein 534
chr10_-_64090265 0.04 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr12_-_118966395 0.02 ENSMUST00000035515.4
Abcb5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr3_+_142620596 0.02 ENSMUST00000165774.1
Gbp2
guanylate binding protein 2
chr4_+_147305674 0.01 ENSMUST00000148762.3
Gm13151
predicted gene 13151
chr5_-_70842617 0.01 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chrX_-_8252304 0.01 ENSMUST00000115594.1
Ftsj1
FtsJ homolog 1 (E. coli)
chr1_+_153665627 0.01 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr8_-_3624989 0.01 ENSMUST00000142431.1
Pcp2
Purkinje cell protein 2 (L7)

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377)
0.6 4.0 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 2.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.3 1.2 GO:2000566 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.2 1.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 0.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012) negative regulation of glial cell migration(GO:1903976)
0.2 1.2 GO:0033762 response to glucagon(GO:0033762)
0.2 1.4 GO:0030242 pexophagy(GO:0030242)
0.2 0.6 GO:0021759 globus pallidus development(GO:0021759)
0.2 2.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.5 GO:0061324 negative regulation of mitotic cell cycle, embryonic(GO:0045976) epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.2 2.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 3.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.9 GO:0019532 oxalate transport(GO:0019532)
0.1 0.6 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.1 0.4 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.5 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.8 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.3 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 1.5 GO:0030903 notochord development(GO:0030903)
0.0 0.8 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 2.0 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 2.1 GO:0006953 acute-phase response(GO:0006953)
0.0 1.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 1.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.7 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.2 1.3 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 1.2 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 1.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 2.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.0 GO:0070469 respiratory chain(GO:0070469)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 3.0 GO:0030426 growth cone(GO:0030426)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.3 1.3 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 1.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 2.2 GO:0044548 S100 protein binding(GO:0044548)
0.1 3.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.6 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 0.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 3.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0043199 sulfate binding(GO:0043199)
0.1 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 2.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.6 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 1.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294) histone methyltransferase binding(GO:1990226)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 0.9 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 3.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants