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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Mef2c

Z-value: 0.56

Motif logo

Transcription factors associated with Mef2c

Gene Symbol Gene ID Gene Info
ENSMUSG00000005583.10 myocyte enhancer factor 2C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mef2cmm10_v2_chr13_+_83573577_835736070.411.4e-02Click!

Activity profile of Mef2c motif

Sorted Z-values of Mef2c motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_98383811 7.73 ENSMUST00000008021.2
titin-cap
chr5_+_122100951 6.70 ENSMUST00000014080.6
ENSMUST00000111750.1
ENSMUST00000139213.1
ENSMUST00000111751.1
ENSMUST00000155612.1
myosin, light polypeptide 2, regulatory, cardiac, slow
chr1_-_66935333 6.32 ENSMUST00000120415.1
ENSMUST00000119429.1
myosin, light polypeptide 1
chr3_-_123034943 5.31 ENSMUST00000029761.7
myozenin 2
chr7_+_142498832 5.21 ENSMUST00000078497.8
ENSMUST00000105953.3
ENSMUST00000179658.1
ENSMUST00000105954.3
ENSMUST00000105952.3
ENSMUST00000105955.1
ENSMUST00000074187.6
ENSMUST00000180152.1
ENSMUST00000105950.4
ENSMUST00000105957.3
ENSMUST00000169299.2
ENSMUST00000105958.3
ENSMUST00000105949.1
troponin T3, skeletal, fast
chr7_+_142441808 4.99 ENSMUST00000105971.1
ENSMUST00000145287.1
troponin I, skeletal, fast 2
chr15_-_77022632 4.64 ENSMUST00000019037.8
ENSMUST00000169226.1
myoglobin
chr11_+_67798269 4.14 ENSMUST00000168612.1
ENSMUST00000040574.4
dehydrogenase/reductase (SDR family) member 7C
chr14_-_34588654 4.14 ENSMUST00000022328.6
ENSMUST00000064098.6
ENSMUST00000022327.5
ENSMUST00000022330.7
LIM domain binding 3
chr9_+_110763646 4.12 ENSMUST00000079784.7
myosin, light polypeptide 3
chr15_-_78206391 4.07 ENSMUST00000120592.1
parvalbumin
chr1_+_40805578 3.92 ENSMUST00000114765.2
transmembrane protein 182
chr1_-_172219715 3.70 ENSMUST00000170700.1
ENSMUST00000003554.4
calsequestrin 1
chr8_+_15057646 3.40 ENSMUST00000033842.3
myomesin 2
chr7_+_142442330 3.29 ENSMUST00000149529.1
troponin I, skeletal, fast 2
chr11_-_94976327 3.22 ENSMUST00000103162.1
ENSMUST00000166320.1
sarcoglycan, alpha (dystrophin-associated glycoprotein)
chr4_+_130308595 3.05 ENSMUST00000070532.7
fatty acid binding protein 3, muscle and heart
chr5_-_112896350 2.86 ENSMUST00000086617.4
myosin XVIIIb
chr14_-_34588607 2.82 ENSMUST00000090040.4
LIM domain binding 3
chr14_-_20664562 2.76 ENSMUST00000119483.1
synaptopodin 2-like
chr7_+_102101736 2.71 ENSMUST00000033300.2
ADP-ribosyltransferase 1
chrX_-_95478107 2.67 ENSMUST00000033549.2
ankyrin repeat and SOCS box-containing 12
chr10_+_33083476 2.50 ENSMUST00000095762.4
triadin
chr7_+_128003911 2.34 ENSMUST00000106248.1
tripartite motif-containing 72
chr3_+_102086471 2.22 ENSMUST00000165540.2
ENSMUST00000164123.1
calsequestrin 2
chr14_-_20668269 2.20 ENSMUST00000057090.5
ENSMUST00000117386.1
synaptopodin 2-like
chr7_-_128206346 2.19 ENSMUST00000033049.7
cytochrome c oxidase subunit VIa polypeptide 2
chr14_-_32685246 2.18 ENSMUST00000096038.3
RIKEN cDNA 3425401B19 gene
chr14_-_54966570 2.17 ENSMUST00000124930.1
ENSMUST00000134256.1
ENSMUST00000081857.6
ENSMUST00000145322.1
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr9_+_121777607 2.14 ENSMUST00000098272.2
kelch-like 40
chr1_+_135799402 2.10 ENSMUST00000152208.1
ENSMUST00000152075.1
ENSMUST00000154463.1
ENSMUST00000139986.1
troponin I, skeletal, slow 1
chr3_+_102086415 2.07 ENSMUST00000029454.5
calsequestrin 2
chr11_+_77462325 2.05 ENSMUST00000102493.1
coronin 6
chr3_+_103074009 2.04 ENSMUST00000090715.6
adenosine monophosphate deaminase 1
chr14_-_21714570 1.91 ENSMUST00000073870.5
dual specificity phosphatase and pro isomerase domain containing 1
chr1_+_135799833 1.90 ENSMUST00000148201.1
troponin I, skeletal, slow 1
chr11_+_67238017 1.86 ENSMUST00000018632.4
myosin, heavy polypeptide 4, skeletal muscle
chr13_-_113663670 1.80 ENSMUST00000054650.4
heat shock protein 3
chr2_-_76982455 1.68 ENSMUST00000011934.5
ENSMUST00000099981.2
ENSMUST00000099980.3
ENSMUST00000111882.2
ENSMUST00000140091.1
titin
chr6_+_30541582 1.66 ENSMUST00000096066.4
carboxypeptidase A2, pancreatic
chr2_+_69670100 1.65 ENSMUST00000100050.3
kelch-like 41
chr3_+_103074035 1.65 ENSMUST00000176440.1
adenosine monophosphate deaminase 1
chr4_-_73950834 1.64 ENSMUST00000095023.1
ENSMUST00000030101.3
RIKEN cDNA 2310002L09 gene
chr2_+_32628390 1.54 ENSMUST00000156578.1
adenylate kinase 1
chr17_+_71019548 1.44 ENSMUST00000073211.5
ENSMUST00000179759.1
myomesin 1
chr11_+_70657196 1.42 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
enolase 3, beta muscle
chr4_+_156215920 1.40 ENSMUST00000105572.1
RIKEN cDNA 2310042D19 gene
chr11_-_107716517 1.39 ENSMUST00000021065.5
calcium channel, voltage-dependent, gamma subunit 1
chr11_+_70657687 1.37 ENSMUST00000134087.1
ENSMUST00000170716.1
enolase 3, beta muscle
chr2_-_104028287 1.33 ENSMUST00000056170.3
RIKEN cDNA 4931422A03 gene
chr17_+_71019503 1.32 ENSMUST00000024847.7
myomesin 1
chr1_-_44019929 1.31 ENSMUST00000061421.3
methyltransferase like 21C
chr6_+_112273758 1.28 ENSMUST00000032376.5
LIM and cysteine-rich domains 1
chr1_+_187608755 1.25 ENSMUST00000127489.1
estrogen-related receptor gamma
chr5_+_66745835 1.23 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
LIM and calponin homology domains 1
chr15_+_25940846 1.22 ENSMUST00000110438.1
family with sequence similarity 134, member B
chr7_-_4514558 1.18 ENSMUST00000163538.1
troponin T1, skeletal, slow
chr19_+_6384395 1.18 ENSMUST00000035269.8
ENSMUST00000113483.1
muscle glycogen phosphorylase
chr14_+_26894557 1.14 ENSMUST00000090337.4
ENSMUST00000165929.2
ankyrin repeat and SOCS box-containing 14
chr2_-_67433181 1.10 ENSMUST00000180773.1
predicted gene, 26727
chr10_+_127501672 1.08 ENSMUST00000160019.1
ENSMUST00000160610.1
SH3 and cysteine rich domain 3
chr4_+_135759705 1.05 ENSMUST00000105854.1
myomesin family, member 3
chr5_+_122101146 1.03 ENSMUST00000147178.1
myosin, light polypeptide 2, regulatory, cardiac, slow
chr4_-_130308674 1.01 ENSMUST00000097865.1
predicted gene 10570
chr7_+_45405960 1.00 ENSMUST00000107774.1
potassium voltage-gated channel, shaker-related subfamily, member 7
chr7_-_4514609 0.96 ENSMUST00000166959.1
troponin T1, skeletal, slow
chr9_-_120023558 0.96 ENSMUST00000111635.2
xin actin-binding repeat containing 1
chr4_+_137862270 0.95 ENSMUST00000130407.1
endothelin converting enzyme 1
chr5_+_92386879 0.95 ENSMUST00000128246.1
ADP-ribosyltransferase 3
chrX_+_164438039 0.94 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr4_+_49059256 0.93 ENSMUST00000076670.2
RIKEN cDNA E130309F12 gene
chr5_-_62765618 0.92 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_+_127501707 0.90 ENSMUST00000035839.2
SH3 and cysteine rich domain 3
chr3_+_32817520 0.90 ENSMUST00000072312.5
ENSMUST00000108228.1
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr11_+_75656103 0.90 ENSMUST00000136935.1
myosin IC
chr2_+_91118136 0.90 ENSMUST00000169776.1
ENSMUST00000111430.3
ENSMUST00000137942.1
myosin binding protein C, cardiac
chr5_-_122002340 0.87 ENSMUST00000134326.1
cut-like homeobox 2
chr15_-_91191733 0.87 ENSMUST00000069511.6
ATP-binding cassette, sub-family D (ALD), member 2
chr8_+_45658273 0.87 ENSMUST00000153798.1
sorbin and SH3 domain containing 2
chr7_+_130865835 0.85 ENSMUST00000075181.4
ENSMUST00000048180.5
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr12_+_88953399 0.83 ENSMUST00000057634.7
neurexin III
chr13_+_83573577 0.81 ENSMUST00000185052.1
myocyte enhancer factor 2C
chr2_+_72054598 0.76 ENSMUST00000028525.5
Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_67445994 0.72 ENSMUST00000112347.1
ENSMUST00000028410.3
xin actin-binding repeat containing 2
chr13_+_37826904 0.70 ENSMUST00000149745.1
ras responsive element binding protein 1
chr7_+_122671378 0.70 ENSMUST00000182563.1
calcium channel, voltage-dependent, gamma subunit 3
chr2_-_77170592 0.67 ENSMUST00000164114.2
ENSMUST00000049544.7
coiled-coil domain containing 141
chr14_+_101840501 0.66 ENSMUST00000159026.1
LIM domain only 7
chrX_+_73774397 0.65 ENSMUST00000002081.5
serine/arginine-rich protein specific kinase 3
chr15_-_58324161 0.64 ENSMUST00000022985.1
kelch-like 38
chr1_+_187609028 0.64 ENSMUST00000110939.1
estrogen-related receptor gamma
chr9_+_77636494 0.63 ENSMUST00000057781.7
kelch-like 31
chr10_+_94550852 0.63 ENSMUST00000148910.1
ENSMUST00000117460.1
transmembrane and coiled coil domains 3
chr5_-_51553896 0.61 ENSMUST00000132734.1
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr14_+_66344296 0.60 ENSMUST00000152093.1
ENSMUST00000074523.6
stathmin-like 4
chr9_-_79977782 0.58 ENSMUST00000093811.4
filamin A interacting protein 1
chrX_+_106583184 0.58 ENSMUST00000101296.2
ENSMUST00000101297.3
predicted gene 5127
chr8_+_31089471 0.57 ENSMUST00000036631.7
ENSMUST00000170204.1
dual specificity phosphatase 26 (putative)
chr6_-_142702259 0.56 ENSMUST00000073173.5
ENSMUST00000111771.1
ENSMUST00000087527.4
ENSMUST00000100827.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr19_+_4003334 0.55 ENSMUST00000025806.3
double C2, gamma
chr5_-_88527841 0.55 ENSMUST00000087033.3
immunoglobulin joining chain
chr6_+_42286676 0.54 ENSMUST00000031894.6
chloride channel 1
chr1_+_135836380 0.53 ENSMUST00000178204.1
troponin T2, cardiac
chr7_+_130865756 0.52 ENSMUST00000120441.1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr9_-_65391652 0.52 ENSMUST00000068307.3
kelch repeat and BTB (POZ) domain containing 13
chr5_+_107497762 0.52 ENSMUST00000152474.1
ENSMUST00000060553.7
RIKEN cDNA A830010M20 gene
chr6_-_128526703 0.50 ENSMUST00000143664.1
ENSMUST00000112132.1
ENSMUST00000032510.7
pregnancy zone protein
chrX_+_159303266 0.50 ENSMUST00000112491.1
ribosomal protein S6 kinase polypeptide 3
chr5_-_24540439 0.50 ENSMUST00000048302.6
ENSMUST00000119657.1
ankyrin repeat and SOCS box-containing 10
chr17_-_14694223 0.49 ENSMUST00000170872.1
thrombospondin 2
chr7_-_4514368 0.49 ENSMUST00000166161.1
troponin T1, skeletal, slow
chr1_-_172329261 0.49 ENSMUST00000062387.2
potassium inwardly-rectifying channel, subfamily J, member 9
chr17_-_67950908 0.49 ENSMUST00000164647.1
Rho GTPase activating protein 28
chr7_-_81566939 0.48 ENSMUST00000042318.5
fibronectin type III and SPRY domain containing 2
chr10_-_69212996 0.48 ENSMUST00000170048.1
RIKEN cDNA A930033H14 gene
chrX_+_56779699 0.48 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
four and a half LIM domains 1
chr5_-_129879038 0.45 ENSMUST00000026617.6
phosphorylase kinase gamma 1
chr7_+_112742025 0.44 ENSMUST00000164363.1
TEA domain family member 1
chr6_+_5390387 0.42 ENSMUST00000183358.1
ankyrin repeat and SOCS box-containing 4
chr13_-_64497792 0.42 ENSMUST00000180282.1
RIKEN cDNA 1190003K10 gene
chr14_+_66344369 0.41 ENSMUST00000118426.1
ENSMUST00000121955.1
ENSMUST00000120229.1
ENSMUST00000134440.1
stathmin-like 4
chr2_+_48949495 0.41 ENSMUST00000112745.1
methyl-CpG binding domain protein 5
chrX_+_56779437 0.40 ENSMUST00000114773.3
four and a half LIM domains 1
chr5_+_66968559 0.39 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr17_+_75435886 0.39 ENSMUST00000164192.1
RAS, guanyl releasing protein 3
chr1_+_75375271 0.39 ENSMUST00000087122.5
SPEG complex locus
chr2_+_27676440 0.38 ENSMUST00000129514.1
retinoid X receptor alpha
chr15_-_89425856 0.38 ENSMUST00000109313.2
carnitine palmitoyltransferase 1b, muscle
chr19_-_5802640 0.38 ENSMUST00000173523.1
ENSMUST00000173499.1
ENSMUST00000172812.2
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr14_-_54966925 0.37 ENSMUST00000111456.1
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr5_-_123141067 0.36 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
expressed sequence AI480526
chr14_+_55575617 0.35 ENSMUST00000022826.5
fat storage-inducing transmembrane protein 1
chr14_-_57058030 0.35 ENSMUST00000061614.6
gap junction protein, alpha 3
chr3_-_142395661 0.34 ENSMUST00000029941.9
ENSMUST00000168967.2
ENSMUST00000090134.5
ENSMUST00000058626.8
PDZ and LIM domain 5
chr1_+_63445842 0.33 ENSMUST00000087374.3
ENSMUST00000114107.1
ENSMUST00000182642.1
a disintegrin and metallopeptidase domain 23
chr8_-_41016749 0.33 ENSMUST00000117735.1
mitochondrial tumor suppressor 1
chr1_-_64122256 0.33 ENSMUST00000135075.1
Kruppel-like factor 7 (ubiquitous)
chr19_-_24861828 0.32 ENSMUST00000047666.4
phosphoglucomutase 5
chr9_+_74953053 0.32 ENSMUST00000170846.1
family with sequence similarity 214, member A
chr16_+_11313812 0.32 ENSMUST00000023140.5
tumor necrosis factor receptor superfamily, member 17
chr13_-_59556845 0.31 ENSMUST00000170378.1
ENSMUST00000169434.1
ATP/GTP binding protein 1
chr15_-_76232045 0.30 ENSMUST00000167754.1
plectin
chr15_-_89425795 0.30 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chr9_-_7873157 0.30 ENSMUST00000159323.1
ENSMUST00000115673.2
baculoviral IAP repeat-containing 3
chr16_+_7069825 0.30 ENSMUST00000056416.7
RNA binding protein, fox-1 homolog (C. elegans) 1
chr18_-_38918642 0.30 ENSMUST00000040647.4
fibroblast growth factor 1
chr14_-_50897456 0.30 ENSMUST00000170855.1
RIKEN cDNA A930018M24 gene
chr10_+_63457505 0.29 ENSMUST00000105440.1
catenin (cadherin associated protein), alpha 3
chr4_-_55532453 0.29 ENSMUST00000132746.1
ENSMUST00000107619.2
Kruppel-like factor 4 (gut)
chr4_-_83021102 0.28 ENSMUST00000071708.5
Fras1 related extracellular matrix protein 1
chr5_-_17888884 0.28 ENSMUST00000169095.1
CD36 antigen
chr1_-_134234492 0.28 ENSMUST00000169927.1
adenosine A1 receptor
chr12_+_69241832 0.27 ENSMUST00000063445.6
kelch domain containing 1
chr8_+_81342556 0.27 ENSMUST00000172167.1
ENSMUST00000169116.1
ENSMUST00000109852.2
ENSMUST00000172031.1
inositol polyphosphate-4-phosphatase, type II
chrX_+_6577259 0.27 ENSMUST00000089520.2
shroom family member 4
chr8_+_40307458 0.27 ENSMUST00000068999.7
mitochondrial calcium uptake family, member 3
chr12_+_109747903 0.26 ENSMUST00000183084.1
ENSMUST00000182300.1
miRNA containing gene
chr1_+_180109192 0.25 ENSMUST00000143176.1
ENSMUST00000135056.1
CDC42 binding protein kinase alpha
chr5_+_25759987 0.24 ENSMUST00000128727.1
ENSMUST00000088244.4
ARP3 actin-related protein 3B
chr6_+_108213086 0.24 ENSMUST00000032192.6
inositol 1,4,5-trisphosphate receptor 1
chr5_-_113081579 0.24 ENSMUST00000131708.1
ENSMUST00000117143.1
ENSMUST00000119627.1
crystallin, beta B3
chr17_+_8283762 0.24 ENSMUST00000155364.1
ENSMUST00000046754.8
ENSMUST00000124023.1
mitochondrial pyruvate carrier 1
chr3_-_149185495 0.24 ENSMUST00000066092.3
predicted gene 9912
chr3_+_51693771 0.23 ENSMUST00000099104.2
predicted gene 10729
chr5_-_24540976 0.23 ENSMUST00000117900.1
ankyrin repeat and SOCS box-containing 10
chr5_+_66968416 0.22 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr14_-_93888732 0.22 ENSMUST00000068992.2
protocadherin 9
chr6_+_21986887 0.22 ENSMUST00000151315.1
cadherin-like and PC-esterase domain containing 1
chr6_-_71262232 0.22 ENSMUST00000129630.2
ENSMUST00000114186.2
ENSMUST00000074301.3
SET and MYND domain containing 1
chr3_+_138143429 0.22 ENSMUST00000040321.6
tRNA methyltransferase 10A
chr13_-_85127514 0.21 ENSMUST00000179230.1
predicted gene 4076
chr12_+_59130994 0.20 ENSMUST00000177460.1
CTAGE family, member 5
chr8_-_61902669 0.20 ENSMUST00000121785.1
ENSMUST00000034057.7
palladin, cytoskeletal associated protein
chr17_+_44188564 0.19 ENSMUST00000024755.5
chloride intracellular channel 5
chr6_-_14755250 0.19 ENSMUST00000045096.4
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr13_+_102693522 0.19 ENSMUST00000022124.3
ENSMUST00000171267.1
ENSMUST00000167144.1
ENSMUST00000170878.1
CD180 antigen
chr10_+_69785507 0.18 ENSMUST00000182993.1
ankyrin 3, epithelial
chr1_-_88702121 0.18 ENSMUST00000159814.1
ADP-ribosylation factor-like 4C
chr3_-_56183678 0.18 ENSMUST00000029374.6
neurobeachin
chr13_-_107890059 0.16 ENSMUST00000105097.2
zinc finger SWIM-type containing 6
chrX_+_164373363 0.15 ENSMUST00000033751.7
c-fos induced growth factor
chr9_-_66514567 0.15 ENSMUST00000056890.8
F-box and leucine-rich repeat protein 22
chr6_+_42286709 0.14 ENSMUST00000163936.1
chloride channel 1
chr18_+_45268876 0.14 ENSMUST00000183850.1
ENSMUST00000066890.7
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr7_-_67372846 0.14 ENSMUST00000156690.1
ENSMUST00000107476.1
ENSMUST00000076325.5
ENSMUST00000032776.8
ENSMUST00000133074.1
myocyte enhancer factor 2A
chr5_+_107497718 0.14 ENSMUST00000112671.2
RIKEN cDNA A830010M20 gene
chr9_+_55326913 0.14 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr3_-_49757257 0.14 ENSMUST00000035931.7
protocadherin 18
chr16_+_30065333 0.12 ENSMUST00000023171.7
hairy and enhancer of split 1 (Drosophila)
chr5_+_65348386 0.12 ENSMUST00000031096.7
klotho beta
chr3_-_51340628 0.12 ENSMUST00000062009.7
E74-like factor 2
chr7_+_30121915 0.11 ENSMUST00000098596.3
ENSMUST00000153792.1
zinc finger protein 382
chr11_+_3330401 0.11 ENSMUST00000045153.4
phosphoinositide-3-kinase interacting protein 1
chr2_+_27165233 0.11 ENSMUST00000000910.6
dopamine beta hydroxylase
chr17_+_12378603 0.10 ENSMUST00000014578.5
plasminogen
chr16_+_45093611 0.10 ENSMUST00000099498.2
coiled-coil domain containing 80
chrX_-_47892396 0.10 ENSMUST00000153548.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr4_+_123201503 0.09 ENSMUST00000068262.5
5'-nucleotidase, cytosolic IA
chr4_+_133553370 0.08 ENSMUST00000042706.2
nuclear receptor subfamily 0, group B, member 2
chr8_-_124569696 0.08 ENSMUST00000063278.6
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2c

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
1.2 3.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.1 7.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.9 4.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.8 2.5 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.8 3.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.7 7.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.5 2.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.5 4.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.5 5.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.4 2.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.4 3.7 GO:0032264 IMP salvage(GO:0032264)
0.4 19.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.3 0.9 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 0.9 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.3 0.8 GO:0007521 muscle cell fate determination(GO:0007521)
0.3 0.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.3 1.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.2 6.8 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.2 14.3 GO:0030239 myofibril assembly(GO:0030239)
0.2 0.8 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.2 0.6 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 1.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 4.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 0.6 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.4 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.3 GO:0070256 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 3.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.9 GO:0014823 response to activity(GO:0014823)
0.1 1.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.4 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.1 0.7 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 1.2 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 4.9 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.4 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.9 GO:0007614 short-term memory(GO:0007614)
0.0 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 4.7 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.5 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0045168 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) cell-cell signaling involved in cell fate commitment(GO:0045168) negative regulation of forebrain neuron differentiation(GO:2000978)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.0 0.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.4 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.0 0.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.9 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.7 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.8 GO:0003012 muscle system process(GO:0003012)
0.0 3.2 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.0 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.1 20.6 GO:0005861 troponin complex(GO:0005861)
0.8 7.3 GO:0097512 cardiac myofibril(GO:0097512)
0.8 2.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4 10.4 GO:0005859 muscle myosin complex(GO:0005859)
0.4 3.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 2.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 5.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 3.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.2 1.9 GO:0032982 myosin filament(GO:0032982)
0.2 32.3 GO:0031674 I band(GO:0031674)
0.2 0.8 GO:0044316 cone cell pedicle(GO:0044316)
0.1 1.0 GO:0031430 M band(GO:0031430)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.2 GO:0005916 fascia adherens(GO:0005916)
0.1 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.5 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 6.0 GO:0016528 sarcoplasm(GO:0016528)
0.1 7.1 GO:0030016 myofibril(GO:0030016)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.3 GO:0016460 myosin II complex(GO:0016460)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 3.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 1.9 GO:0042383 sarcolemma(GO:0042383)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.0 GO:0090537 CERF complex(GO:0090537)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 13.0 GO:0051373 FATZ binding(GO:0051373)
1.3 7.8 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
1.1 10.9 GO:0031014 troponin T binding(GO:0031014)
0.6 15.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 3.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 3.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 3.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 2.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.3 11.8 GO:0003785 actin monomer binding(GO:0003785)
0.3 0.5 GO:0030172 troponin C binding(GO:0030172)
0.3 3.7 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 0.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.7 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 1.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 2.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 1.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.8 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 2.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 4.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.7 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0071820 N-box binding(GO:0071820)
0.0 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 1.5 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 14.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 8.8 GO:0003779 actin binding(GO:0003779)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 2.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.0 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.0 7.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.7 ST ADRENERGIC Adrenergic Pathway
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 43.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.7 REACTOME DEFENSINS Genes involved in Defensins
0.2 3.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 3.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)