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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Otx1

Z-value: 1.13

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Transcription factors associated with Otx1

Gene Symbol Gene ID Gene Info
Otx1
ENSMUSG00000005917.9 orthodenticle homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Otx1mm10_v2_chr11_-_22001605_22001631-0.096.1e-01Click!

Activity profile of Otx1 motif

Sorted Z-values of Otx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_60921270 7.38 ENSMUST00000096418.3
A1bg
alpha-1-B glycoprotein
chr14_+_37068042 6.00 ENSMUST00000057176.3
Lrit2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr10_+_127801145 5.96 ENSMUST00000071646.1
Rdh16
retinol dehydrogenase 16
chr13_+_4436094 3.29 ENSMUST00000156277.1
Akr1c6
aldo-keto reductase family 1, member C6
chr16_-_46010212 3.17 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr7_-_100662414 3.07 ENSMUST00000079176.6
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr7_-_100662315 3.04 ENSMUST00000151123.1
ENSMUST00000107047.2
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr11_-_120453473 2.87 ENSMUST00000026452.2
Pde6g
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr5_-_87092546 2.77 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
Ugt2b36
UDP glucuronosyltransferase 2 family, polypeptide B36
chr5_+_87000838 2.73 ENSMUST00000031186.7
Ugt2b35
UDP glucuronosyltransferase 2 family, polypeptide B35
chr2_+_177897096 2.14 ENSMUST00000108935.1
Gm14327
predicted gene 14327
chr6_+_48589560 2.04 ENSMUST00000181661.1
Gm5111
predicted gene 5111
chr10_+_61648552 1.92 ENSMUST00000020286.6
Ppa1
pyrophosphatase (inorganic) 1
chr6_-_148831395 1.90 ENSMUST00000145960.1
Ipo8
importin 8
chr7_-_80403315 1.78 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr12_+_103434211 1.74 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27
interferon, alpha-inducible protein 27
chr5_-_87424201 1.74 ENSMUST00000072818.5
Ugt2b38
UDP glucuronosyltransferase 2 family, polypeptide B38
chr10_+_29313164 1.64 ENSMUST00000160399.1
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr9_-_66975387 1.47 ENSMUST00000034929.6
Lactb
lactamase, beta
chr11_+_101665541 1.43 ENSMUST00000039388.2
Arl4d
ADP-ribosylation factor-like 4D
chrM_+_10167 1.42 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr7_-_79848191 1.40 ENSMUST00000107392.1
Anpep
alanyl (membrane) aminopeptidase
chr9_-_64341288 1.30 ENSMUST00000068367.7
Dis3l
DIS3 mitotic control homolog (S. cerevisiae)-like
chr2_+_175275125 1.27 ENSMUST00000109051.1
Gm14440
predicted gene 14440
chr19_+_4097392 1.25 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2
CDK2-associated protein 2
chr2_-_86347764 1.24 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr1_-_187215454 1.18 ENSMUST00000183819.1
Spata17
spermatogenesis associated 17
chr16_+_23107754 1.04 ENSMUST00000077605.5
ENSMUST00000115341.3
Eif4a2
eukaryotic translation initiation factor 4A2
chr13_+_93771656 1.04 ENSMUST00000091403.4
Arsb
arylsulfatase B
chr6_-_29507946 1.03 ENSMUST00000101614.3
ENSMUST00000078112.6
Kcp
kielin/chordin-like protein
chr2_+_158502633 0.96 ENSMUST00000109484.1
Adig
adipogenin
chr1_-_24612700 0.94 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr4_-_42661893 0.93 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr16_-_59632520 0.91 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr1_-_187215421 0.88 ENSMUST00000110945.3
ENSMUST00000183931.1
ENSMUST00000027908.6
Spata17
spermatogenesis associated 17
chr8_+_46151749 0.85 ENSMUST00000154040.1
4933411K20Rik
RIKEN cDNA 4933411K20 gene
chr2_+_86297817 0.77 ENSMUST00000054746.2
Olfr1052
olfactory receptor 1052
chr17_-_45686899 0.77 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr3_-_105960099 0.77 ENSMUST00000118209.1
Atp5f1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1
chr2_+_129800451 0.76 ENSMUST00000165413.2
ENSMUST00000166282.2
Stk35
serine/threonine kinase 35
chr11_+_100545607 0.76 ENSMUST00000092684.5
ENSMUST00000006976.7
Ttc25
tetratricopeptide repeat domain 25
chr2_+_158502612 0.75 ENSMUST00000059889.3
Adig
adipogenin
chr2_-_110305730 0.75 ENSMUST00000046233.2
Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr2_+_178023284 0.74 ENSMUST00000108925.3
ENSMUST00000108926.2
Etohi1
ethanol induced 1
chr17_+_8165501 0.74 ENSMUST00000097419.3
ENSMUST00000024636.8
Fgfr1op
Fgfr1 oncogene partner
chrX_-_48513518 0.69 ENSMUST00000114945.2
ENSMUST00000037349.7
Aifm1
apoptosis-inducing factor, mitochondrion-associated 1
chr9_+_68653761 0.68 ENSMUST00000034766.7
Rora
RAR-related orphan receptor alpha
chrX_-_8461726 0.68 ENSMUST00000103000.2
ENSMUST00000023931.3
Ssxb2
synovial sarcoma, X member B, breakpoint 2
chr4_-_138819251 0.66 ENSMUST00000102512.4
Pla2g5
phospholipase A2, group V
chr14_-_122913751 0.65 ENSMUST00000160401.1
Ggact
gamma-glutamylamine cyclotransferase
chrX_-_95956890 0.62 ENSMUST00000079987.6
ENSMUST00000113864.2
Las1l
LAS1-like (S. cerevisiae)
chr13_+_21735055 0.62 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr19_-_6057736 0.61 ENSMUST00000007482.6
Mrpl49
mitochondrial ribosomal protein L49
chr7_-_7247328 0.61 ENSMUST00000170922.1
Vmn2r29
vomeronasal 2, receptor 29
chr3_+_66985947 0.60 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr8_-_46151705 0.59 ENSMUST00000041582.8
Snx25
sorting nexin 25
chr16_-_48771956 0.59 ENSMUST00000170861.1
Trat1
T cell receptor associated transmembrane adaptor 1
chr13_-_92030897 0.57 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr10_+_127642975 0.57 ENSMUST00000092074.5
ENSMUST00000120279.1
Stat6
signal transducer and activator of transcription 6
chr18_+_23954668 0.57 ENSMUST00000060762.4
Zfp397
zinc finger protein 397
chr7_-_9223653 0.56 ENSMUST00000072787.4
Vmn2r37
vomeronasal 2, receptor 37
chr5_-_62765618 0.55 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_-_26933781 0.53 ENSMUST00000154651.1
ENSMUST00000015011.3
Surf4
surfeit gene 4
chrX_+_8413305 0.51 ENSMUST00000037297.3
Ssxb1
synovial sarcoma, X member B, breakpoint 1
chr3_+_66985647 0.50 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1
arginine/serine-rich coiled-coil 1
chr7_-_7337493 0.50 ENSMUST00000072475.6
ENSMUST00000174368.1
Vmn2r30
vomeronasal 2, receptor 30
chr6_+_58833689 0.49 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr1_-_118311132 0.49 ENSMUST00000027623.7
Tsn
translin
chr5_+_109923400 0.48 ENSMUST00000112544.1
Gm15446
predicted gene 15446
chr6_-_88518760 0.47 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr10_+_123264076 0.46 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr9_-_104102550 0.45 ENSMUST00000050139.4
Ackr4
atypical chemokine receptor 4
chr7_-_7689513 0.45 ENSMUST00000173459.1
Vmn2r34
vomeronasal 2, receptor 34
chr12_-_20815718 0.43 ENSMUST00000110971.2
1700030C10Rik
RIKEN cDNA 1700030C10 gene
chr7_-_8200242 0.42 ENSMUST00000142934.1
ENSMUST00000146278.1
ENSMUST00000086282.5
Vmn2r42
vomeronasal 2, receptor 42
chr8_-_64987646 0.42 ENSMUST00000095295.1
Trim75
tripartite motif-containing 75
chr7_+_17812633 0.42 ENSMUST00000023953.4
Ceacam14
carcinoembryonic antigen-related cell adhesion molecule 14
chr13_+_41016250 0.42 ENSMUST00000021790.5
Tmem14c
transmembrane protein 14C
chr10_+_80054029 0.41 ENSMUST00000097227.3
Gpx4
glutathione peroxidase 4
chr18_-_46597299 0.37 ENSMUST00000036030.7
Tmed7
transmembrane emp24 protein transport domain containing 7
chr8_-_122622739 0.36 ENSMUST00000093059.2
Pabpn1l
poly(A)binding protein nuclear 1-like
chr2_+_28468056 0.36 ENSMUST00000038600.3
Mrps2
mitochondrial ribosomal protein S2
chr4_-_123750236 0.35 ENSMUST00000102636.3
Akirin1
akirin 1
chr7_-_109731708 0.33 ENSMUST00000035372.1
Ascl3
achaete-scute complex homolog 3 (Drosophila)
chr2_+_129065934 0.33 ENSMUST00000035812.7
Ttl
tubulin tyrosine ligase
chr11_+_103116228 0.33 ENSMUST00000053063.5
Hexim1
hexamethylene bis-acetamide inducible 1
chrX_+_21068406 0.32 ENSMUST00000040437.5
Spaca5
sperm acrosome associated 5
chr14_+_29968308 0.32 ENSMUST00000112268.1
Selk
selenoprotein K
chrM_+_11734 0.31 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr2_-_144011202 0.30 ENSMUST00000016072.5
ENSMUST00000037875.5
Rrbp1
ribosome binding protein 1
chr17_+_56628118 0.29 ENSMUST00000112979.2
Catsperd
catsper channel auxiliary subunit delta
chrX_+_107089234 0.28 ENSMUST00000118666.1
ENSMUST00000053375.3
P2ry10
purinergic receptor P2Y, G-protein coupled 10
chr4_+_74242468 0.28 ENSMUST00000077851.3
Kdm4c
lysine (K)-specific demethylase 4C
chr14_+_105258673 0.25 ENSMUST00000136040.2
Ndfip2
Nedd4 family interacting protein 2
chr12_-_98259416 0.25 ENSMUST00000021390.7
Galc
galactosylceramidase
chr5_-_100373484 0.25 ENSMUST00000182433.1
Sec31a
Sec31 homolog A (S. cerevisiae)
chr7_-_102888151 0.25 ENSMUST00000078191.2
Olfr569
olfactory receptor 569
chr13_-_55321928 0.25 ENSMUST00000035242.7
Rab24
RAB24, member RAS oncogene family
chr7_-_83550258 0.25 ENSMUST00000177929.1
Gm10610
predicted gene 10610
chr19_-_7039987 0.24 ENSMUST00000025918.7
Stip1
stress-induced phosphoprotein 1
chr7_-_118129567 0.24 ENSMUST00000032888.7
Arl6ip1
ADP-ribosylation factor-like 6 interacting protein 1
chr2_+_112284561 0.23 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr6_+_134396316 0.23 ENSMUST00000032321.4
Bcl2l14
BCL2-like 14 (apoptosis facilitator)
chr7_-_9841325 0.22 ENSMUST00000170131.1
Vmn2r47
vomeronasal 2, receptor 47
chrX_+_107816477 0.22 ENSMUST00000143975.1
ENSMUST00000144695.1
ENSMUST00000167154.1
Fam46d
family with sequence similarity 46, member D
chrX_+_37126777 0.22 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr18_+_86711520 0.21 ENSMUST00000122464.1
Cbln2
cerebellin 2 precursor protein
chr7_-_9572288 0.21 ENSMUST00000174433.1
Gm10302
predicted gene 10302
chr2_-_156180135 0.20 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
Rbm39
RNA binding motif protein 39
chr14_-_54605908 0.20 ENSMUST00000022786.4
4931414P19Rik
RIKEN cDNA 4931414P19 gene
chr7_-_45179539 0.19 ENSMUST00000179443.1
Gm581
predicted gene 581
chr19_+_41933464 0.19 ENSMUST00000026154.7
Zdhhc16
zinc finger, DHHC domain containing 16
chr8_-_47675556 0.19 ENSMUST00000125536.1
Ing2
inhibitor of growth family, member 2
chr12_-_27160311 0.19 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866
predicted gene 9866
chr13_-_21750505 0.18 ENSMUST00000102983.1
Hist1h4k
histone cluster 1, H4k
chr2_-_11603192 0.18 ENSMUST00000040314.5
Rbm17
RNA binding motif protein 17
chr13_+_18717289 0.18 ENSMUST00000072961.4
Vps41
vacuolar protein sorting 41 (yeast)
chr13_+_90089705 0.18 ENSMUST00000012566.8
Tmem167
transmembrane protein 167
chr14_-_74947865 0.16 ENSMUST00000088970.5
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr4_-_132422484 0.14 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr7_-_9953585 0.14 ENSMUST00000165611.1
Vmn2r48
vomeronasal 2, receptor 48
chr9_-_20521375 0.13 ENSMUST00000068296.7
ENSMUST00000174462.1
Zfp266
zinc finger protein 266
chr3_-_92851284 0.13 ENSMUST00000054426.4
Lce1l
late cornified envelope 1L
chr9_-_109082372 0.12 ENSMUST00000167504.1
Tma7
translational machinery associated 7 homolog (S. cerevisiae)
chr10_-_107912134 0.12 ENSMUST00000165341.3
Otogl
otogelin-like
chr16_+_91647859 0.12 ENSMUST00000119368.1
ENSMUST00000114037.2
ENSMUST00000114036.2
ENSMUST00000122302.1
Son
Son DNA binding protein
chr7_-_38271310 0.12 ENSMUST00000032585.6
Pop4
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
chr4_-_113999500 0.11 ENSMUST00000169631.1
ENSMUST00000170105.1
ENSMUST00000171627.2
Skint5
selection and upkeep of intraepithelial T cells 5
chr11_-_116274197 0.11 ENSMUST00000021133.9
Srp68
signal recognition particle 68
chr2_-_120057497 0.08 ENSMUST00000156159.1
Sptbn5
spectrin beta, non-erythrocytic 5
chr9_-_39957069 0.08 ENSMUST00000169307.2
Olfr976
olfactory receptor 976
chr18_+_57468478 0.07 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr5_-_37336870 0.07 ENSMUST00000031005.4
Evc
Ellis van Creveld gene syndrome
chr12_-_3426700 0.05 ENSMUST00000180149.1
1110002L01Rik
RIKEN cDNA 1110002L01 gene
chr1_+_133131143 0.04 ENSMUST00000052529.3
Ppp1r15b
protein phosphatase 1, regulatory (inhibitor) subunit 15b
chr11_-_116274102 0.04 ENSMUST00000106425.3
Srp68
signal recognition particle 68
chr19_-_39812744 0.04 ENSMUST00000162507.1
ENSMUST00000160476.1
Cyp2c40
cytochrome P450, family 2, subfamily c, polypeptide 40
chr1_+_131910458 0.03 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr7_-_7479973 0.03 ENSMUST00000094866.4
Vmn2r32
vomeronasal 2, receptor 32
chr19_-_5688908 0.02 ENSMUST00000113615.2
Pcnxl3
pecanex-like 3 (Drosophila)
chr4_-_41517326 0.01 ENSMUST00000030152.6
ENSMUST00000095126.4
1110017D15Rik
RIKEN cDNA 1110017D15 gene
chr6_-_129784270 0.01 ENSMUST00000118532.1
Gm156
predicted gene 156

Network of associatons between targets according to the STRING database.

First level regulatory network of Otx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.9 6.0 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 1.8 GO:0090472 dibasic protein processing(GO:0090472)
0.2 0.9 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 0.6 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.2 0.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.7 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 1.4 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 2.9 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.5 GO:0039019 pronephric nephron development(GO:0039019)
0.1 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.7 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 1.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.7 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.7 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.6 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0 0.8 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.2 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 1.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.0 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.0 GO:0009268 response to pH(GO:0009268)
0.0 0.7 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.6 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.0 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.3 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 2.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0031983 vesicle lumen(GO:0031983)
0.1 6.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 6.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 7.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.7 GO:0070469 respiratory chain(GO:0070469)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.5 1.6 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.5 1.9 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 6.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 7.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 1.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.7 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 2.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.7 GO:0005521 lamin binding(GO:0005521)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.6 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.4 GO:0008430 selenium binding(GO:0008430)
0.0 2.0 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 3.2 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0032029 myosin tail binding(GO:0032029)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 4.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 2.6 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.7 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 2.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 2.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC