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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Prdm4

Z-value: 0.23

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Transcription factors associated with Prdm4

Gene Symbol Gene ID Gene Info
ENSMUSG00000035529.9 PR domain containing 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prdm4mm10_v2_chr10_-_85916902_85917006-0.343.9e-02Click!

Activity profile of Prdm4 motif

Sorted Z-values of Prdm4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_44198191 0.51 ENSMUST00000085450.2
kallikrein 1-related peptidase b3
chr11_-_69369377 0.36 ENSMUST00000092971.6
ENSMUST00000108661.1
chromodomain helicase DNA binding protein 3
chr2_+_97467657 0.34 ENSMUST00000059049.7
leucine rich repeat containing 4C
chr8_+_27042555 0.33 ENSMUST00000033875.8
ENSMUST00000098851.4
proline synthetase co-transcribed
chr10_+_26822560 0.32 ENSMUST00000135866.1
Rho GTPase activating protein 18
chrX_+_21714896 0.31 ENSMUST00000033414.7
solute carrier family 6 (neurotransmitter transporter), member 14
chr18_+_42053692 0.29 ENSMUST00000074679.3
SH3 domain containing ring finger 2
chr11_-_43836243 0.29 ENSMUST00000167574.1
adrenergic receptor, alpha 1b
chr5_-_144965793 0.26 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
SMAD specific E3 ubiquitin protein ligase 1
chr5_-_142817654 0.25 ENSMUST00000151477.1
trinucleotide repeat containing 18
chr1_+_74391479 0.24 ENSMUST00000027367.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr18_+_42053648 0.23 ENSMUST00000072008.4
SH3 domain containing ring finger 2
chr3_+_37348645 0.23 ENSMUST00000038885.3
fibroblast growth factor 2
chr5_-_142817387 0.21 ENSMUST00000036253.6
trinucleotide repeat containing 18
chr7_+_43975963 0.15 ENSMUST00000081399.3
kallikrein 1-related peptidase b9
chr15_-_99474696 0.12 ENSMUST00000040313.4
BCDIN3 domain containing
chr12_+_51377560 0.08 ENSMUST00000021335.5
Sec1 family domain containing 1
chr7_+_43966739 0.08 ENSMUST00000078835.2
kallikrein 1-related peptidase b1
chr10_+_126978690 0.02 ENSMUST00000105256.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chrX_-_7605374 0.01 ENSMUST00000033483.4
coiled-coil domain containing 22

Network of associatons between targets according to the STRING database.

First level regulatory network of Prdm4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.1 0.3 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.2 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)