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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Prop1

Z-value: 1.73

Motif logo

Transcription factors associated with Prop1

Gene Symbol Gene ID Gene Info
ENSMUSG00000044542.3 paired like homeodomain factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prop1mm10_v2_chr11_-_50953745_50953768-0.095.9e-01Click!

Activity profile of Prop1 motif

Sorted Z-values of Prop1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39287074 15.95 ENSMUST00000003137.8
cytochrome P450, family 2, subfamily c, polypeptide 29
chr10_+_128971191 10.42 ENSMUST00000181142.1
RIKEN cDNA 9030616G12 gene
chr7_-_14446570 9.30 ENSMUST00000063509.4
RIKEN cDNA 2810007J24 gene
chr1_+_130826762 9.26 ENSMUST00000133792.1
polymeric immunoglobulin receptor
chr7_-_14446651 9.02 ENSMUST00000125941.1
RIKEN cDNA 2810007J24 gene
chr5_-_87091150 8.62 ENSMUST00000154455.1
UDP glucuronosyltransferase 2 family, polypeptide B36
chr3_+_138415484 6.38 ENSMUST00000161312.1
ENSMUST00000013458.8
alcohol dehydrogenase 4 (class II), pi polypeptide
chr17_+_79626669 6.37 ENSMUST00000086570.1
RIKEN cDNA 4921513D11 gene
chr4_-_96664112 6.26 ENSMUST00000030299.7
cytochrome P450, family 2, subfamily j, polypeptide 5
chr9_+_78230644 6.08 ENSMUST00000098537.3
glutathione S-transferase, alpha 1 (Ya)
chr1_+_167598450 6.03 ENSMUST00000111386.1
ENSMUST00000111384.1
retinoid X receptor gamma
chr1_+_167598384 5.56 ENSMUST00000015987.3
retinoid X receptor gamma
chr8_-_5105232 5.16 ENSMUST00000023835.1
solute carrier family 10, member 2
chr2_-_67194695 4.71 ENSMUST00000147939.1
predicted gene 13598
chr10_-_115362191 4.68 ENSMUST00000092170.5
transmembrane protein 19
chr19_-_40187277 4.66 ENSMUST00000051846.6
cytochrome P450, family 2, subfamily c, polypeptide 70
chr10_-_41587753 4.56 ENSMUST00000160751.1
coiled-coil domain containing 162
chr5_-_87482258 4.51 ENSMUST00000079811.6
ENSMUST00000144144.1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr1_-_130661613 4.47 ENSMUST00000027657.7
complement component 4 binding protein
chr5_+_130369420 4.42 ENSMUST00000086029.3
calneuron 1
chr1_-_130661584 4.42 ENSMUST00000137276.2
complement component 4 binding protein
chr11_-_46707059 4.35 ENSMUST00000055102.6
ENSMUST00000125008.1
T cell immunoglobulin and mucin domain containing 2
chr18_-_38866702 4.25 ENSMUST00000115582.1
fibroblast growth factor 1
chr16_+_56204313 4.21 ENSMUST00000160116.1
ENSMUST00000069936.7
interphotoreceptor matrix proteoglycan 2
chr19_-_39649046 4.09 ENSMUST00000067328.6
cytochrome P450, family 2, subfamily c, polypeptide 67
chr3_+_94377505 4.06 ENSMUST00000098877.2
RAR-related orphan receptor gamma
chr3_+_94377432 3.98 ENSMUST00000107292.1
RAR-related orphan receptor gamma
chr5_-_87535113 3.76 ENSMUST00000120150.1
sulfotransferase family 1B, member 1
chr4_+_115600975 3.74 ENSMUST00000084342.5
cytochrome P450, family 4, subfamily a, polypeptide 32
chr3_-_67515487 3.60 ENSMUST00000178314.1
ENSMUST00000054825.4
retinoic acid receptor responder (tazarotene induced) 1
chr2_+_70474923 3.54 ENSMUST00000100043.2
trans-acting transcription factor 5
chr19_+_11536769 3.54 ENSMUST00000025581.6
membrane-spanning 4-domains, subfamily A, member 4D
chr5_-_89457763 3.52 ENSMUST00000049209.8
group specific component
chr3_+_138217814 3.43 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chrX_+_38772671 3.30 ENSMUST00000050744.5
RIKEN cDNA 6030498E09 gene
chr9_+_53301571 3.27 ENSMUST00000051014.1
exophilin 5
chr7_+_132610620 3.23 ENSMUST00000033241.5
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr17_+_85028347 3.22 ENSMUST00000024944.7
solute carrier family 3, member 1
chrX_-_100594860 3.22 ENSMUST00000053373.1
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr11_+_102041509 3.14 ENSMUST00000123895.1
ENSMUST00000017453.5
ENSMUST00000107163.2
ENSMUST00000107164.2
CD300 antigen like family member G
chr8_+_127447669 3.12 ENSMUST00000159511.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr19_+_12674179 3.07 ENSMUST00000057924.2
olfactory receptor 1442
chr12_-_57546121 3.06 ENSMUST00000044380.6
forkhead box A1
chr10_-_92375367 2.98 ENSMUST00000182870.1
predicted gene, 20757
chr6_+_149141513 2.93 ENSMUST00000047531.9
ENSMUST00000179873.1
ENSMUST00000111548.1
ENSMUST00000111547.1
ENSMUST00000134306.1
methyltransferase like 20
chr10_-_109009055 2.93 ENSMUST00000156979.1
synaptotagmin I
chr18_-_3299537 2.85 ENSMUST00000129435.1
ENSMUST00000122958.1
cAMP responsive element modulator
chr2_-_164638789 2.81 ENSMUST00000109336.1
WAP four-disulfide core domain 16
chr11_-_43901187 2.78 ENSMUST00000067258.2
ENSMUST00000139906.1
adrenergic receptor, alpha 1b
chr12_+_9029982 2.77 ENSMUST00000085741.1
tetratricopeptide repeat domain 32
chr6_+_149141638 2.73 ENSMUST00000166416.1
ENSMUST00000111551.1
methyltransferase like 20
chr9_+_7347374 2.69 ENSMUST00000065079.5
ENSMUST00000005950.5
matrix metallopeptidase 12
chr3_+_122419772 2.69 ENSMUST00000029766.4
breast cancer anti-estrogen resistance 3
chr6_+_3993776 2.66 ENSMUST00000031673.5
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr11_-_12412136 2.59 ENSMUST00000174874.1
cordon-bleu WH2 repeat
chr7_-_34655500 2.57 ENSMUST00000032709.1
potassium channel tetramerisation domain containing 15
chr3_-_146495115 2.50 ENSMUST00000093951.2
spermatogenesis associated 1
chrX_-_147429189 2.40 ENSMUST00000033646.2
interleukin 13 receptor, alpha 2
chr13_+_67833235 2.34 ENSMUST00000060609.7
predicted gene 10037
chr12_-_79190955 2.33 ENSMUST00000085254.6
retinol dehydrogenase 11
chr18_-_3299452 2.32 ENSMUST00000126578.1
cAMP responsive element modulator
chr4_+_102430047 2.32 ENSMUST00000172616.1
phosphodiesterase 4B, cAMP specific
chr2_-_86347764 2.29 ENSMUST00000099894.2
olfactory receptor 1055
chr2_-_110305730 2.23 ENSMUST00000046233.2
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr19_-_7966000 2.12 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr17_-_83846769 2.10 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr6_-_115592571 2.09 ENSMUST00000112957.1
RIKEN cDNA 2510049J12 gene
chr5_+_42067960 2.08 ENSMUST00000087332.4
predicted gene 16223
chr4_-_82505707 2.08 ENSMUST00000107248.1
ENSMUST00000107247.1
nuclear factor I/B
chr19_+_26749726 2.07 ENSMUST00000175842.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_-_108217897 2.06 ENSMUST00000106690.1
ENSMUST00000043793.6
zyg-11 family member A, cell cycle regulator
chr14_-_45477856 2.06 ENSMUST00000141424.1
fermitin family homolog 2 (Drosophila)
chr3_+_122895072 2.05 ENSMUST00000023820.5
fatty acid binding protein 2, intestinal
chr16_+_20097554 2.02 ENSMUST00000023509.3
kelch-like 24
chr3_-_10331358 1.96 ENSMUST00000065938.8
ENSMUST00000118410.1
inositol (myo)-1(or 4)-monophosphatase 1
chr7_+_101321079 1.92 ENSMUST00000032927.7
START domain containing 10
chr9_-_71163224 1.89 ENSMUST00000074465.2
aquaporin 9
chr4_+_99030946 1.79 ENSMUST00000030280.6
angiopoietin-like 3
chr13_-_56548534 1.76 ENSMUST00000062806.4
leukocyte cell-derived chemotaxin 2
chr11_-_49113757 1.75 ENSMUST00000060398.1
olfactory receptor 1396
chr17_-_45599603 1.67 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
solute carrier family 29 (nucleoside transporters), member 1
chr18_+_32067729 1.66 ENSMUST00000025243.3
IWS1 homolog (S. cerevisiae)
chrX_-_165004829 1.62 ENSMUST00000114890.2
predicted gene, 17604
chr2_-_134554348 1.61 ENSMUST00000028704.2
hydroxyacid oxidase 1, liver
chr19_-_4698668 1.58 ENSMUST00000177696.1
predicted gene 960
chr9_+_66946057 1.57 ENSMUST00000040917.7
ENSMUST00000127896.1
ribosomal protein S27-like
chr1_-_24005608 1.52 ENSMUST00000027338.3
RIKEN cDNA 1110058L19 gene
chr9_+_80165079 1.48 ENSMUST00000184480.1
myosin VI
chr5_+_92137896 1.46 ENSMUST00000031355.6
USO1 vesicle docking factor
chr1_+_187997835 1.46 ENSMUST00000110938.1
estrogen-related receptor gamma
chr6_-_83121385 1.44 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
WW domain binding protein 1
chr5_-_62766153 1.44 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_73173825 1.42 ENSMUST00000166875.1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr12_+_59129757 1.40 ENSMUST00000069430.8
ENSMUST00000177370.1
CTAGE family, member 5
chr5_+_7960445 1.38 ENSMUST00000115421.1
STEAP family member 4
chr6_+_115422040 1.37 ENSMUST00000000450.3
peroxisome proliferator activated receptor gamma
chr17_+_64600702 1.37 ENSMUST00000086723.3
mannosidase 2, alpha 1
chr11_-_54249640 1.35 ENSMUST00000019060.5
colony stimulating factor 2 (granulocyte-macrophage)
chr16_-_22811399 1.34 ENSMUST00000040592.4
crystallin, gamma S
chr10_+_80141457 1.32 ENSMUST00000105367.1
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr5_-_90223923 1.32 ENSMUST00000118816.1
ENSMUST00000048363.7
cytochrome c oxidase assembly protein 18
chr1_-_163725123 1.30 ENSMUST00000159679.1
methyltransferase like 11B
chr9_-_121857952 1.30 ENSMUST00000060251.6
HIG1 domain family, member 1A
chr7_+_105375053 1.29 ENSMUST00000106805.2
predicted gene 5901
chr7_+_62476306 1.28 ENSMUST00000097132.3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g, pseudogene 1
chr4_-_14826582 1.28 ENSMUST00000117268.1
OTU domain containing 6B
chr12_+_59129720 1.26 ENSMUST00000175912.1
ENSMUST00000176892.1
CTAGE family, member 5
chr12_-_104473236 1.26 ENSMUST00000021513.4
goosecoid homeobox
chr4_+_95557494 1.25 ENSMUST00000079223.4
ENSMUST00000177394.1
FGGY carbohydrate kinase domain containing
chr3_-_92123943 1.24 ENSMUST00000070284.3
proline rich 9
chr15_+_76343504 1.23 ENSMUST00000023210.6
cytochrome c-1
chr4_-_12087912 1.21 ENSMUST00000050686.3
transmembrane protein 67
chr8_+_13060908 1.21 ENSMUST00000033822.2
protein Z, vitamin K-dependent plasma glycoprotein
chr1_+_58711488 1.20 ENSMUST00000097722.2
ENSMUST00000114313.1
CASP8 and FADD-like apoptosis regulator
chr2_+_82053222 1.19 ENSMUST00000047527.7
zinc finger protein 804A
chr13_-_4609122 1.17 ENSMUST00000110691.3
ENSMUST00000091848.5
aldo-keto reductase family 1, member E1
chr18_+_3382979 1.15 ENSMUST00000025073.5
cullin 2
chr9_+_118478182 1.14 ENSMUST00000111763.1
eomesodermin homolog (Xenopus laevis)
chr1_+_187997821 1.13 ENSMUST00000027906.6
estrogen-related receptor gamma
chr19_-_39812744 1.11 ENSMUST00000162507.1
ENSMUST00000160476.1
cytochrome P450, family 2, subfamily c, polypeptide 40
chr3_-_116712644 1.08 ENSMUST00000029569.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_-_82505749 1.07 ENSMUST00000107245.2
ENSMUST00000107246.1
nuclear factor I/B
chr1_-_186117251 1.07 ENSMUST00000045388.7
lysophospholipase-like 1
chrX_+_38600626 1.07 ENSMUST00000000365.2
malignant T cell amplified sequence 1
chr4_-_41517326 1.05 ENSMUST00000030152.6
ENSMUST00000095126.4
RIKEN cDNA 1110017D15 gene
chr18_+_38296805 1.05 ENSMUST00000171461.1
ring finger protein 14
chr11_+_109543694 1.04 ENSMUST00000106696.1
arylsulfatase G
chrX_+_56963325 1.03 ENSMUST00000096431.3
G protein-coupled receptor 112
chr2_-_33942111 1.02 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
predicted gene 13403
chr8_+_47822143 1.02 ENSMUST00000079639.2
claudin 24
chrX_-_134276888 1.00 ENSMUST00000113252.1
TRM2 tRNA methyltransferase 2B
chr13_+_40704005 0.99 ENSMUST00000069457.1
predicted gene 9979
chr16_-_64771146 0.99 ENSMUST00000076991.6
RIKEN cDNA 4930453N24 gene
chrM_+_10167 0.98 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr12_+_85110833 0.97 ENSMUST00000053811.8
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr14_+_73237891 0.96 ENSMUST00000044405.6
lysophosphatidic acid receptor 6
chr14_+_74735641 0.95 ENSMUST00000177283.1
esterase D/formylglutathione hydrolase
chr5_+_104170676 0.94 ENSMUST00000112771.1
dentin sialophosphoprotein
chrM_+_2743 0.94 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr3_-_116712696 0.93 ENSMUST00000169530.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_+_116507549 0.93 ENSMUST00000106479.1
ENSMUST00000030461.4
IAP promoted placental gene
chr2_+_85975213 0.92 ENSMUST00000082191.2
olfactory receptor 1029
chr10_+_69925954 0.91 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
ankyrin 3, epithelial
chrM_+_9870 0.90 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr1_-_171240055 0.89 ENSMUST00000131286.1
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr10_+_69925766 0.89 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
ankyrin 3, epithelial
chr9_+_119341487 0.89 ENSMUST00000175743.1
ENSMUST00000176397.1
acetyl-Coenzyme A acyltransferase 1A
chr1_+_37872333 0.88 ENSMUST00000142670.1
lipoyltransferase 1
chr9_+_105642957 0.87 ENSMUST00000065778.6
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
chr9_+_119341294 0.85 ENSMUST00000039784.5
acetyl-Coenzyme A acyltransferase 1A
chr17_+_94873986 0.84 ENSMUST00000108007.4
predicted gene, 20939
chr2_+_20737306 0.84 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chrX_-_134276969 0.84 ENSMUST00000087541.5
ENSMUST00000087540.3
TRM2 tRNA methyltransferase 2B
chr18_-_9282754 0.84 ENSMUST00000041007.3
gap junction protein, delta 4
chr10_+_69925800 0.83 ENSMUST00000182029.1
ankyrin 3, epithelial
chrX_+_103630575 0.83 ENSMUST00000033692.7
zinc finger, CCHC domain containing 13
chr12_+_31390843 0.82 ENSMUST00000167432.1
solute carrier family 26, member 3
chr1_-_56969864 0.80 ENSMUST00000177424.1
special AT-rich sequence binding protein 2
chr18_+_74442551 0.77 ENSMUST00000121875.1
myosin VB
chr5_-_129708511 0.76 ENSMUST00000182386.1
septin 14
chr14_-_48667508 0.76 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
orthodenticle homolog 2 (Drosophila)
chr9_-_59353430 0.76 ENSMUST00000026265.6
Bardet-Biedl syndrome 4 (human)
chr8_-_85432841 0.76 ENSMUST00000047749.5
RIKEN cDNA 4921524J17 gene
chr4_-_110292719 0.76 ENSMUST00000106601.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr7_-_30856178 0.76 ENSMUST00000094583.1
free fatty acid receptor 3
chr9_+_118478344 0.76 ENSMUST00000035020.8
eomesodermin homolog (Xenopus laevis)
chr12_-_87919857 0.76 ENSMUST00000180053.1
predicted pseudogene 2035
chr6_-_136173492 0.76 ENSMUST00000111905.1
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr7_+_66365905 0.74 ENSMUST00000107486.1
predicted gene 10974
chr6_-_117214048 0.74 ENSMUST00000170447.1
ribosomal protein L28, pseudogene 4
chr6_+_63255971 0.74 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr5_-_86745787 0.73 ENSMUST00000161306.1
transmembrane protease, serine 11e
chr11_-_117873433 0.73 ENSMUST00000033230.7
threonine aldolase 1
chrM_+_7759 0.69 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr8_-_21327015 0.69 ENSMUST00000098890.3
defensin, alpha, related sequence 1
chr8_+_21509258 0.68 ENSMUST00000084042.3
defensin, alpha, 20
chr16_+_4741543 0.68 ENSMUST00000120232.1
heme oxygenase (decycling) 2
chr1_-_24612700 0.67 ENSMUST00000088336.1
predicted gene 10222
chr16_-_55283237 0.67 ENSMUST00000036412.3
zona pellucida like domain containing 1
chr2_-_112480817 0.66 ENSMUST00000099589.2
cholinergic receptor, muscarinic 5
chr12_-_84617326 0.66 ENSMUST00000021666.4
ATP-binding cassette, sub-family D (ALD), member 4
chr4_+_35152056 0.65 ENSMUST00000058595.6
interferon kappa
chr2_-_176149825 0.65 ENSMUST00000109049.3
ENSMUST00000179349.1
predicted gene 2004
chr11_+_101087277 0.65 ENSMUST00000107302.1
ENSMUST00000107303.3
ENSMUST00000017945.8
ENSMUST00000149597.1
MAX-like protein X
chr14_+_52726612 0.65 ENSMUST00000184883.1
T cell receptor alpha variable 6D-3
chr1_+_37872206 0.65 ENSMUST00000041621.3
lipoyltransferase 1
chr7_-_24724237 0.64 ENSMUST00000081657.4
predicted gene 4763
chr3_+_32436376 0.62 ENSMUST00000108242.1
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr5_-_123666682 0.60 ENSMUST00000149410.1
CAP-GLY domain containing linker protein 1
chr14_+_4709238 0.60 ENSMUST00000169465.1
ENSMUST00000171305.1
predicted gene 7876
chr3_-_96905294 0.60 ENSMUST00000029738.7
G protein-coupled receptor 89
chr11_-_99337930 0.59 ENSMUST00000100482.2
keratin 26
chr3_+_83026147 0.59 ENSMUST00000166581.1
ENSMUST00000029630.9
fibrinogen alpha chain
chr10_+_69925484 0.58 ENSMUST00000182692.1
ENSMUST00000092433.5
ankyrin 3, epithelial
chr19_-_45235811 0.58 ENSMUST00000099401.4
ladybird homeobox homolog 1 (Drosophila)
chr19_-_19001099 0.58 ENSMUST00000040153.8
ENSMUST00000112828.1
RAR-related orphan receptor beta
chr2_+_125136692 0.58 ENSMUST00000099452.2
cortexin 2
chr8_+_21665797 0.58 ENSMUST00000075268.4
predicted gene 15315
chr7_+_126976338 0.58 ENSMUST00000032920.3
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr18_+_52615908 0.57 ENSMUST00000072666.3
zinc finger protein 474

Network of associatons between targets according to the STRING database.

First level regulatory network of Prop1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
2.5 9.8 GO:0006069 ethanol oxidation(GO:0006069)
2.1 6.3 GO:2000863 positive regulation of estrogen secretion(GO:2000863)
1.3 3.8 GO:0006067 ethanol metabolic process(GO:0006067)
1.0 3.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.9 2.8 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.8 4.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.8 26.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.8 3.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 8.0 GO:0072615 interleukin-17 secretion(GO:0072615)
0.6 2.3 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.6 2.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.6 1.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.5 3.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.5 1.6 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.5 0.5 GO:1904444 regulation of establishment of Sertoli cell barrier(GO:1904444)
0.5 3.1 GO:0003383 apical constriction(GO:0003383)
0.5 1.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.5 1.9 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.5 1.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.5 1.4 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.4 2.7 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.4 2.0 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.4 3.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.4 1.2 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.4 2.6 GO:0001757 somite specification(GO:0001757)
0.4 1.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.3 1.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 0.9 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.3 0.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 7.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 3.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 11.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.3 2.9 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.1 GO:0002188 translation reinitiation(GO:0002188)
0.3 2.4 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.3 4.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 2.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.3 0.8 GO:0002879 regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.2 1.7 GO:0015862 uridine transport(GO:0015862)
0.2 1.7 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.2 6.1 GO:0035634 response to stilbenoid(GO:0035634)
0.2 2.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.7 GO:0006788 heme oxidation(GO:0006788)
0.2 0.8 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.2 1.2 GO:0033762 response to glucagon(GO:0033762) mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 3.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 0.8 GO:0032439 endosome localization(GO:0032439)
0.2 1.4 GO:0042045 epithelial fluid transport(GO:0042045)
0.2 0.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 5.7 GO:0097286 iron ion import(GO:0097286)
0.2 0.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 1.3 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.2 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 0.7 GO:0006566 threonine metabolic process(GO:0006566)
0.2 1.1 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.2 8.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.5 GO:1905223 epicardium morphogenesis(GO:1905223)
0.2 0.8 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 2.0 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.8 GO:1902019 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 1.4 GO:0006013 mannose metabolic process(GO:0006013)
0.2 2.1 GO:0015747 urate transport(GO:0015747)
0.2 0.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 3.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.8 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.9 GO:0030242 pexophagy(GO:0030242)
0.1 1.0 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.3 GO:0014029 neural crest formation(GO:0014029)
0.1 1.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 1.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.6 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1 0.9 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.5 GO:0015817 histidine transport(GO:0015817)
0.1 1.2 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.1 0.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 5.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.3 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 1.3 GO:0019321 pentose metabolic process(GO:0019321)
0.1 1.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:1903999 negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.1 2.6 GO:0007602 phototransduction(GO:0007602)
0.1 2.0 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 1.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.6 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1 2.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.6 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 1.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.1 GO:0042407 cristae formation(GO:0042407)
0.1 0.2 GO:0014878 regulation of muscle atrophy(GO:0014735) response to muscle activity involved in regulation of muscle adaptation(GO:0014873) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 2.0 GO:0050892 intestinal absorption(GO:0050892)
0.1 1.7 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 0.2 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.7 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.5 GO:1900042 common-partner SMAD protein phosphorylation(GO:0007182) positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.9 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.4 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 1.3 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 1.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.4 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 1.0 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 1.3 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.1 GO:2000791 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.0 2.1 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 1.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 2.1 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 1.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.6 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 0.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 1.8 GO:0008033 tRNA processing(GO:0008033)
0.0 2.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467) regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 1.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 2.0 GO:0007608 sensory perception of smell(GO:0007608)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.6 1.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.4 3.1 GO:0033269 internode region of axon(GO:0033269)
0.3 2.6 GO:1990357 terminal web(GO:1990357)
0.3 0.9 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 1.2 GO:0030891 VCB complex(GO:0030891)
0.2 9.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 2.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 1.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 2.8 GO:0045179 apical cortex(GO:0045179)
0.2 2.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 2.9 GO:0031045 dense core granule(GO:0031045)
0.2 3.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 4.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0005745 m-AAA complex(GO:0005745)
0.1 3.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.1 GO:0002177 manchette(GO:0002177)
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 1.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.5 GO:0008091 spectrin(GO:0008091) cuticular plate(GO:0032437)
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.6 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.2 GO:0036038 MKS complex(GO:0036038)
0.1 2.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 9.1 GO:0005902 microvillus(GO:0005902)
0.1 1.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 2.0 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 4.9 GO:0070469 respiratory chain(GO:0070469)
0.1 1.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 4.0 GO:0031526 brush border membrane(GO:0031526)
0.0 1.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 8.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 8.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.0 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
2.7 15.9 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.6 8.0 GO:0008142 oxysterol binding(GO:0008142)
1.2 3.5 GO:1902271 D3 vitamins binding(GO:1902271)
1.2 11.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.1 3.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.9 9.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.9 4.3 GO:0070287 ferritin receptor activity(GO:0070287)
0.8 3.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.8 3.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.7 5.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.7 2.9 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 2.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.7 2.0 GO:0031403 lithium ion binding(GO:0031403)
0.6 3.7 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.5 1.5 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.5 12.5 GO:0070330 aromatase activity(GO:0070330)
0.4 1.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.4 1.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.4 3.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.4 1.9 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.4 1.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.3 13.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 2.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 1.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 1.6 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 0.9 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.3 1.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 2.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 1.7 GO:0008410 CoA-transferase activity(GO:0008410) palmitoyl-CoA oxidase activity(GO:0016401)
0.3 4.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 4.2 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.7 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 2.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 6.1 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 4.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.7 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 1.6 GO:0008494 translation activator activity(GO:0008494)
0.2 0.9 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.7 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 2.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.4 GO:0050544 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.4 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 3.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 7.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.3 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.1 1.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.1 2.1 GO:0019825 oxygen binding(GO:0019825)
0.1 0.8 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 2.0 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.8 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.8 GO:0005549 odorant binding(GO:0005549)
0.1 2.3 GO:0030552 cAMP binding(GO:0030552)
0.1 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 1.2 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0001566 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.0 2.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.5 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 2.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 2.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.6 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 3.8 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.2 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.9 GO:0003774 motor activity(GO:0003774)
0.0 1.3 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 1.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 13.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 5.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 6.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.6 5.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.5 2.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.3 4.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 3.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 24.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 4.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 2.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 2.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 1.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 6.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 5.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 3.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.9 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 2.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 3.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins