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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Rela_Rel_Nfkb1

Z-value: 0.96

Motif logo

Transcription factors associated with Rela_Rel_Nfkb1

Gene Symbol Gene ID Gene Info
ENSMUSG00000024927.7 v-rel reticuloendotheliosis viral oncogene homolog A (avian)
ENSMUSG00000020275.8 reticuloendotheliosis oncogene
ENSMUSG00000028163.11 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Relmm10_v2_chr11_-_23770953_237710280.473.9e-03Click!
Nfkb1mm10_v2_chr3_-_135691512_1356915640.411.3e-02Click!
Relamm10_v2_chr19_+_5637475_56374860.212.1e-01Click!

Activity profile of Rela_Rel_Nfkb1 motif

Sorted Z-values of Rela_Rel_Nfkb1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_90891234 4.37 ENSMUST00000031327.8
chemokine (C-X-C motif) ligand 1
chr17_+_37193889 3.33 ENSMUST00000038844.6
ubiquitin D
chr1_+_74791516 2.88 ENSMUST00000006718.8
wingless related MMTV integration site 10a
chr11_-_82179808 1.94 ENSMUST00000108189.2
ENSMUST00000021043.4
chemokine (C-C motif) ligand 1
chr15_-_78495059 1.74 ENSMUST00000089398.1
interleukin 2 receptor, beta chain
chr12_+_111166485 1.64 ENSMUST00000139162.1
TNF receptor-associated factor 3
chr11_-_83530505 1.57 ENSMUST00000035938.2
chemokine (C-C motif) ligand 5
chr14_-_45529964 1.52 ENSMUST00000150660.1
fermitin family homolog 2 (Drosophila)
chr7_+_26061495 1.42 ENSMUST00000005669.7
cytochrome P450, family 2, subfamily b, polypeptide 13
chr5_-_92348871 1.39 ENSMUST00000038816.6
ENSMUST00000118006.1
chemokine (C-X-C motif) ligand 10
chr1_-_172590463 1.33 ENSMUST00000065679.6
SLAM family member 8
chr18_+_60803838 1.26 ENSMUST00000050487.8
ENSMUST00000097563.2
ENSMUST00000167610.1
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr9_-_14615473 1.22 ENSMUST00000162901.1
angiomotin-like 1
chr4_+_150927918 1.21 ENSMUST00000139826.1
ENSMUST00000116257.1
tumor necrosis factor receptor superfamily, member 9
chr5_+_7960445 1.19 ENSMUST00000115421.1
STEAP family member 4
chr17_+_24878724 1.16 ENSMUST00000050714.6
insulin-like growth factor binding protein, acid labile subunit
chr8_-_61902669 1.15 ENSMUST00000121785.1
ENSMUST00000034057.7
palladin, cytoskeletal associated protein
chr10_-_95415484 1.14 ENSMUST00000172070.1
ENSMUST00000150432.1
suppressor of cytokine signaling 2
chr17_-_34287770 1.14 ENSMUST00000174751.1
ENSMUST00000040655.6
histocompatibility 2, class II antigen A, alpha
chr13_+_112464070 1.11 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
interleukin 6 signal transducer
chr5_+_92925400 1.11 ENSMUST00000172706.1
shroom family member 3
chr7_-_99626936 1.07 ENSMUST00000178124.1
predicted gene 4980
chr11_-_23770953 1.06 ENSMUST00000102864.3
reticuloendotheliosis oncogene
chr3_+_153973436 0.97 ENSMUST00000089948.5
solute carrier family 44, member 5
chr19_-_58455161 0.96 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr11_-_48994172 0.93 ENSMUST00000146439.1
T cell specific GTPase 1
chr10_-_95415283 0.90 ENSMUST00000119917.1
suppressor of cytokine signaling 2
chr17_-_35000848 0.87 ENSMUST00000166828.3
DNA segment, Chr 17, human D6S56E 5
chr17_-_56005566 0.87 ENSMUST00000043785.6
signal transducing adaptor family member 2
chr11_+_101176041 0.86 ENSMUST00000103109.3
contactin associated protein-like 1
chr9_-_45009590 0.84 ENSMUST00000102832.1
CD3 antigen, epsilon polypeptide
chr19_-_58454435 0.83 ENSMUST00000169850.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr15_-_89410230 0.83 ENSMUST00000109314.2
synaptonemal complex central element protein 3
chr17_-_45686899 0.81 ENSMUST00000156254.1
transmembrane protein 63b
chr5_-_105293699 0.79 ENSMUST00000050011.8
guanylate binding protein 6
chr17_-_28517509 0.75 ENSMUST00000114792.1
ENSMUST00000177939.1
FK506 binding protein 5
chr9_+_55326913 0.74 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr12_+_111166413 0.72 ENSMUST00000021706.4
TNF receptor-associated factor 3
chr10_-_19015347 0.71 ENSMUST00000019997.4
tumor necrosis factor, alpha-induced protein 3
chr19_-_58454580 0.70 ENSMUST00000129100.1
ENSMUST00000123957.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr9_-_44735189 0.68 ENSMUST00000034611.8
pleckstrin homology-like domain, family B, member 1
chr11_+_87664549 0.68 ENSMUST00000121782.2
ring finger protein 43
chr16_+_31422268 0.68 ENSMUST00000089759.2
3-hydroxybutyrate dehydrogenase, type 1
chr12_+_111166536 0.66 ENSMUST00000060274.6
TNF receptor-associated factor 3
chr7_-_19629355 0.66 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
avian reticuloendotheliosis viral (v-rel) oncogene related B
chr16_-_45693658 0.65 ENSMUST00000114562.2
ENSMUST00000036617.7
transmembrane serine protease 7
chr5_-_92328068 0.65 ENSMUST00000113093.3
chemokine (C-X-C motif) ligand 9
chr7_+_30421724 0.63 ENSMUST00000108176.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr10_+_111506286 0.63 ENSMUST00000164773.1
pleckstrin homology-like domain, family A, member 1
chr4_-_45012093 0.63 ENSMUST00000131991.1
zinc finger and BTB domain containing 5
chr7_+_30422389 0.63 ENSMUST00000108175.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr3_+_90080442 0.63 ENSMUST00000127955.1
tropomyosin 3, gamma
chr12_+_104214538 0.61 ENSMUST00000121337.1
ENSMUST00000167049.1
ENSMUST00000101080.1
serine (or cysteine) peptidase inhibitor, clade A, member 3F
chr11_+_87664274 0.60 ENSMUST00000092800.5
ring finger protein 43
chr9_-_14614949 0.60 ENSMUST00000013220.6
ENSMUST00000160770.1
angiomotin-like 1
chr9_+_107906866 0.60 ENSMUST00000035203.7
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr3_+_142496924 0.59 ENSMUST00000090127.2
guanylate binding protein 5
chr2_-_160313616 0.59 ENSMUST00000109475.2
predicted gene 826
chr11_+_100860326 0.58 ENSMUST00000138083.1
signal transducer and activator of transcription 5A
chr11_-_99493112 0.57 ENSMUST00000006969.7
keratin 23
chr1_+_171250416 0.57 ENSMUST00000111315.1
ENSMUST00000006570.5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
chr7_-_126200413 0.56 ENSMUST00000163959.1
exportin 6
chr2_-_167060417 0.56 ENSMUST00000155281.1
zinc finger, NFX1-type containing 1
chr9_+_90162978 0.56 ENSMUST00000113060.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr17_-_34862473 0.55 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr9_+_90163057 0.55 ENSMUST00000113059.1
ENSMUST00000167122.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr18_-_4352944 0.55 ENSMUST00000025078.2
mitogen-activated protein kinase kinase kinase 8
chr2_-_156839790 0.53 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
predicted gene 14230
chr14_-_45530118 0.53 ENSMUST00000045905.6
fermitin family homolog 2 (Drosophila)
chr7_+_122671378 0.51 ENSMUST00000182563.1
calcium channel, voltage-dependent, gamma subunit 3
chr9_-_44526397 0.51 ENSMUST00000062215.7
chemokine (C-X-C motif) receptor 5
chr10_-_127751707 0.51 ENSMUST00000079692.5
G protein-coupled receptor 182
chr16_+_32914094 0.51 ENSMUST00000023491.6
ENSMUST00000170899.1
ENSMUST00000171118.1
ENSMUST00000170201.1
ENSMUST00000165616.1
ENSMUST00000135193.2
leucine-rich repeats and calponin homology (CH) domain containing 3
chr9_+_124021965 0.49 ENSMUST00000039171.7
chemokine (C-C motif) receptor 3
chr15_-_79164477 0.49 ENSMUST00000040019.4
SRY-box containing gene 10
chr4_-_96664112 0.48 ENSMUST00000030299.7
cytochrome P450, family 2, subfamily j, polypeptide 5
chr2_-_120314141 0.47 ENSMUST00000054651.7
phospholipase A2, group IVF
chr5_-_105139539 0.46 ENSMUST00000100961.4
ENSMUST00000031235.6
ENSMUST00000100962.3
guanylate-binding protein 9
guanylate-binding protein 8
guanylate binding protein 4
chr18_-_20059478 0.45 ENSMUST00000075214.2
ENSMUST00000039247.4
desmocollin 2
chr1_+_171214013 0.45 ENSMUST00000111328.1
nuclear receptor subfamily 1, group I, member 3
chrX_+_36112110 0.44 ENSMUST00000033418.7
interleukin 13 receptor, alpha 1
chr7_+_28766747 0.44 ENSMUST00000170068.1
ENSMUST00000072965.4
sirtuin 2
chr12_+_111166349 0.43 ENSMUST00000117269.1
TNF receptor-associated factor 3
chr7_-_44815658 0.43 ENSMUST00000107893.1
activating transcription factor 5
chr18_-_38929148 0.43 ENSMUST00000134864.1
fibroblast growth factor 1
chr15_-_89170688 0.43 ENSMUST00000060808.9
plexin B2
chr5_+_106609098 0.43 ENSMUST00000167618.1
predicted gene, 17304
chr1_-_135258449 0.42 ENSMUST00000003135.7
E74-like factor 3
chr6_-_129275360 0.42 ENSMUST00000032259.3
CD69 antigen
chr16_-_55838827 0.42 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr2_-_6213033 0.42 ENSMUST00000042658.2
enoyl Coenzyme A hydratase domain containing 3
chr2_+_91259822 0.41 ENSMUST00000138470.1
protein kinase C and casein kinase substrate in neurons 3
chr4_+_131921771 0.41 ENSMUST00000094666.3
transmembrane protein 200B
chr17_-_35702297 0.41 ENSMUST00000135078.1
discoidin domain receptor family, member 1
chr4_+_85205417 0.41 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
SH3-domain GRB2-like 2
chr18_+_4994600 0.40 ENSMUST00000140448.1
supervillin
chr17_+_47688992 0.40 ENSMUST00000156118.1
fibroblast growth factor receptor substrate 3
chr8_-_84042540 0.40 ENSMUST00000005601.7
interleukin 27 receptor, alpha
chr14_+_33941021 0.39 ENSMUST00000100720.1
growth differentiation factor 2
chr17_-_24205514 0.39 ENSMUST00000097376.3
ENSMUST00000168410.2
ENSMUST00000167791.2
ENSMUST00000040474.7
TBC1 domain family, member 24
chr12_+_86678685 0.39 ENSMUST00000021681.3
vasohibin 1
chr2_+_144556306 0.39 ENSMUST00000155876.1
ENSMUST00000149697.1
SEC23B (S. cerevisiae)
chr1_+_171213969 0.37 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
nuclear receptor subfamily 1, group I, member 3
chr3_+_18054258 0.37 ENSMUST00000026120.6
basic helix-loop-helix family, member e22
chr10_-_41709297 0.37 ENSMUST00000019955.9
ENSMUST00000099932.3
coiled-coil domain containing 162
chr2_-_5063996 0.37 ENSMUST00000114996.1
optineurin
chr18_+_37477768 0.37 ENSMUST00000051442.5
protocadherin beta 16
chr2_-_160327494 0.37 ENSMUST00000099127.2
predicted gene 826
chr16_-_33056174 0.37 ENSMUST00000115100.1
ENSMUST00000040309.8
IQ motif containing G
chr7_+_96211656 0.36 ENSMUST00000107165.1
teneurin transmembrane protein 4
chr16_+_45093611 0.36 ENSMUST00000099498.2
coiled-coil domain containing 80
chr9_-_70934808 0.36 ENSMUST00000034731.8
lipase, hepatic
chr7_+_48959089 0.36 ENSMUST00000183659.1
neuron navigator 2
chr11_+_84129649 0.36 ENSMUST00000133811.1
acetyl-Coenzyme A carboxylase alpha
chr14_+_53704007 0.36 ENSMUST00000103664.4
T cell receptor alpha variable 5-4
chr17_+_32685610 0.35 ENSMUST00000168171.1
cytochrome P450, family 4, subfamily f, polypeptide 15
chr17_+_32685655 0.35 ENSMUST00000008801.6
cytochrome P450, family 4, subfamily f, polypeptide 15
chr10_-_81430966 0.35 ENSMUST00000117966.1
nuclear factor I/C
chr3_+_96601084 0.35 ENSMUST00000062058.3
Lix1-like
chr8_+_71676233 0.34 ENSMUST00000110013.3
ENSMUST00000051995.7
Janus kinase 3
chr15_+_99717515 0.34 ENSMUST00000023760.6
ENSMUST00000162194.1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr17_+_35424842 0.33 ENSMUST00000174699.1
histocompatibility 2, Q region locus 6
chr3_-_84305385 0.33 ENSMUST00000122849.1
ENSMUST00000132283.1
tripartite motif-containing 2
chr8_-_25101734 0.33 ENSMUST00000098866.4
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr18_+_36560581 0.33 ENSMUST00000155329.2
ankyrin repeat and KH domain containing 1
chr14_-_36968679 0.33 ENSMUST00000067700.6
coiled-coil serine rich 2
chr7_-_31111148 0.33 ENSMUST00000164929.1
hepsin
chr18_-_15403680 0.33 ENSMUST00000079081.6
aquaporin 4
chr1_+_165302625 0.33 ENSMUST00000111450.1
G protein-coupled receptor 161
chr4_+_102589687 0.32 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr14_-_70429072 0.32 ENSMUST00000048129.4
piwi-like RNA-mediated gene silencing 2
chr17_+_35379608 0.32 ENSMUST00000081435.4
histocompatibility 2, Q region locus 4
chr10_+_4611971 0.32 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chr11_+_100860447 0.32 ENSMUST00000107357.2
signal transducer and activator of transcription 5A
chr1_+_130800902 0.32 ENSMUST00000112477.2
ENSMUST00000027670.3
Fc receptor, IgA, IgM, high affinity
chr3_-_135691512 0.32 ENSMUST00000029812.7
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr1_+_88055467 0.31 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr11_-_77519186 0.31 ENSMUST00000100807.2
predicted gene 10392
chr3_+_92316705 0.31 ENSMUST00000061038.2
small proline-rich protein 2B
chr7_+_27029074 0.31 ENSMUST00000075552.5
cytochrome P450, family 2, subfamily a, polypeptide 12
chr15_-_76918010 0.31 ENSMUST00000048854.7
zinc finger protein 647
chr6_-_124741374 0.31 ENSMUST00000004389.5
gene rich cluster, C10 gene
chr6_-_18030435 0.31 ENSMUST00000010941.2
wingless-related MMTV integration site 2
chr11_+_100859492 0.30 ENSMUST00000107356.1
signal transducer and activator of transcription 5A
chr11_+_48838672 0.30 ENSMUST00000129674.1
tripartite motif-containing 7
chr16_+_32431225 0.30 ENSMUST00000115140.1
phosphate cytidylyltransferase 1, choline, alpha isoform
chr2_+_92185438 0.30 ENSMUST00000128781.2
PHD finger protein 21A
chr8_+_36457548 0.30 ENSMUST00000135373.1
ENSMUST00000147525.1
RIKEN cDNA 6430573F11 gene
chr2_+_124089961 0.29 ENSMUST00000103241.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr10_+_13966268 0.29 ENSMUST00000015645.4
human immunodeficiency virus type I enhancer binding protein 2
chr3_-_113258837 0.29 ENSMUST00000098673.3
amylase 2a5
chr6_-_24956106 0.29 ENSMUST00000127247.2
transmembrane protein 229A
chr7_-_25788635 0.29 ENSMUST00000002677.4
ENSMUST00000085948.4
AXL receptor tyrosine kinase
chr9_-_41157459 0.29 ENSMUST00000136530.1
ubiquitin associated and SH3 domain containing, B
chr11_+_49087022 0.29 ENSMUST00000046704.6
interferon gamma inducible protein 47
chr3_+_142620596 0.29 ENSMUST00000165774.1
guanylate binding protein 2
chr7_+_75848338 0.29 ENSMUST00000092073.5
ENSMUST00000171155.2
kelch-like 25
chr17_+_34187545 0.28 ENSMUST00000170086.1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_35979679 0.28 ENSMUST00000173724.1
ENSMUST00000172900.1
ENSMUST00000174849.1
proline-rich polypeptide 3
chr10_-_87008015 0.28 ENSMUST00000035288.8
stabilin 2
chr17_-_45685973 0.28 ENSMUST00000145873.1
transmembrane protein 63b
chr16_-_11176056 0.28 ENSMUST00000142389.1
ENSMUST00000138185.1
zinc finger CCCH type containing 7 A
chr17_+_45555693 0.28 ENSMUST00000024742.7
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr13_+_33964659 0.28 ENSMUST00000021843.5
ENSMUST00000058978.7
NAD(P)H dehydrogenase, quinone 2
chr2_-_104028287 0.27 ENSMUST00000056170.3
RIKEN cDNA 4931422A03 gene
chr6_+_129577893 0.27 ENSMUST00000053708.6
killer cell lectin-like receptor family E member 1
chr13_+_55152640 0.27 ENSMUST00000005452.5
fibroblast growth factor receptor 4
chr9_+_65265173 0.27 ENSMUST00000048762.1
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr14_-_7994563 0.27 ENSMUST00000026315.7
deoxyribonuclease 1-like 3
chr17_-_45686120 0.27 ENSMUST00000143907.1
ENSMUST00000127065.1
transmembrane protein 63b
chr8_+_71597648 0.27 ENSMUST00000143662.1
family with sequence similarity 129, member C
chr18_-_35722330 0.27 ENSMUST00000133064.1
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr10_+_128790903 0.27 ENSMUST00000026411.6
matrix metallopeptidase 19
chr17_+_34187789 0.26 ENSMUST00000041633.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr9_-_7873157 0.26 ENSMUST00000159323.1
ENSMUST00000115673.2
baculoviral IAP repeat-containing 3
chr3_-_83841767 0.26 ENSMUST00000029623.9
toll-like receptor 2
chr10_+_25359798 0.26 ENSMUST00000053748.8
erythrocyte protein band 4.1-like 2
chr6_+_48841633 0.26 ENSMUST00000168406.1
transmembrane protein 176A
chr14_-_77036641 0.26 ENSMUST00000062789.8
laccase (multicopper oxidoreductase) domain containing 1
chr5_-_5663263 0.26 ENSMUST00000148193.1
RIKEN cDNA A330021E22 gene
chr10_-_77089428 0.26 ENSMUST00000156009.1
collagen, type XVIII, alpha 1
chr2_-_5063932 0.26 ENSMUST00000027986.4
optineurin
chr6_+_48841476 0.26 ENSMUST00000101426.4
transmembrane protein 176A
chr16_-_18235074 0.26 ENSMUST00000076957.5
zinc finger, DHHC domain containing 8
chr1_+_88055377 0.26 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr1_+_164048214 0.25 ENSMUST00000027874.5
selectin, endothelial cell
chr14_-_103843685 0.25 ENSMUST00000172237.1
endothelin receptor type B
chr18_+_51117754 0.25 ENSMUST00000116639.2
proline rich 16
chr10_+_86705811 0.25 ENSMUST00000061458.7
ENSMUST00000075632.6
cDNA sequence BC030307
chr2_-_181202789 0.25 ENSMUST00000016511.5
PTK6 protein tyrosine kinase 6
chr17_+_8236031 0.25 ENSMUST00000164411.2
chemokine (C-C motif) receptor 6
chr7_-_126200397 0.25 ENSMUST00000009344.9
exportin 6
chr8_+_67490758 0.25 ENSMUST00000026677.3
N-acetyl transferase 1
chr4_+_42240639 0.24 ENSMUST00000117202.2
predicted gene 10600
chr11_+_101552188 0.24 ENSMUST00000147239.1
neighbor of Brca1 gene 1
chr7_+_101108768 0.24 ENSMUST00000098250.3
ENSMUST00000032931.7
FCH and double SH3 domains 2
chrX_-_100594860 0.24 ENSMUST00000053373.1
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr4_+_42091207 0.24 ENSMUST00000178882.1
predicted gene 3893
chr1_-_36273425 0.24 ENSMUST00000056946.6
neuralized homolog 3 homolog (Drosophila)
chr19_-_5845471 0.24 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)

Network of associatons between targets according to the STRING database.

First level regulatory network of Rela_Rel_Nfkb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.5 1.8 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.4 1.6 GO:2000503 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 1.8 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.4 1.1 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.3 3.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.3 1.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.3 1.2 GO:0060376 positive regulation of mast cell differentiation(GO:0060376)
0.3 1.3 GO:1902623 leukocyte chemotaxis involved in inflammatory response(GO:0002232) negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of neutrophil migration(GO:1902623)
0.3 0.8 GO:0002631 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.3 1.3 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 0.5 GO:2000863 positive regulation of estrogen secretion(GO:2000863)
0.2 3.3 GO:0070842 aggresome assembly(GO:0070842)
0.2 1.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 2.7 GO:0048733 sebaceous gland development(GO:0048733)
0.2 0.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 0.8 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.6 GO:0097048 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.1 1.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 1.3 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.4 GO:0035962 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.4 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.1 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.3 GO:0000239 pachytene(GO:0000239)
0.1 0.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.7 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 0.3 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 1.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 2.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.4 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.3 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1 0.3 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 0.4 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.1 1.7 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 0.5 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 1.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.5 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 1.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 2.0 GO:0033622 integrin activation(GO:0033622)
0.1 0.4 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.1 GO:1904170 regulation of bleb assembly(GO:1904170)
0.1 0.2 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.1 1.5 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 0.3 GO:0070295 renal water absorption(GO:0070295)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 0.7 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.1 GO:0046271 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.1 0.3 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.3 GO:0032329 serine transport(GO:0032329)
0.1 0.2 GO:1990743 protein sialylation(GO:1990743)
0.1 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.3 GO:0060750 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 1.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.1 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.3 GO:0007494 midgut development(GO:0007494)
0.0 1.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.5 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.2 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0090135 actin filament branching(GO:0090135) negative regulation of phospholipase C activity(GO:1900275) activation of protein kinase C activity(GO:1990051)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 1.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.4 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.5 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.1 GO:0015881 creatine transport(GO:0015881)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.2 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 1.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:2001182 regulation of interleukin-12 secretion(GO:2001182)
0.0 0.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0061235 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0021658 rhombomere 3 morphogenesis(GO:0021658)
0.0 0.2 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.0 0.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.5 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.0 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:1990839 response to endothelin(GO:1990839)
0.0 0.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.0 0.0 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0 0.5 GO:0001967 suckling behavior(GO:0001967)
0.0 0.1 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:0071236 cellular response to antibiotic(GO:0071236)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.0 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293) positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 1.1 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0021830 substrate-independent telencephalic tangential migration(GO:0021826) interneuron migration from the subpallium to the cortex(GO:0021830) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.0 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.0 0.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.0 GO:0072553 terminal button organization(GO:0072553)
0.0 1.0 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.2 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.3 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0090650 memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.0 GO:0032385 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0035933 glucocorticoid secretion(GO:0035933) regulation of glucocorticoid secretion(GO:2000849)
0.0 0.3 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 3.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 1.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 2.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 1.0 GO:0000801 central element(GO:0000801)
0.1 1.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.7 GO:0042825 TAP complex(GO:0042825)
0.1 0.4 GO:0033010 paranodal junction(GO:0033010)
0.1 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 3.5 GO:0016235 aggresome(GO:0016235)
0.0 2.3 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 0.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.4 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 2.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0005914 spot adherens junction(GO:0005914)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 1.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 0.5 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0018995 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 8.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0097386 glial cell projection(GO:0097386)
0.0 4.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0043293 apoptosome(GO:0043293)
0.0 0.0 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.5 1.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 5.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.4 2.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 1.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.2 3.6 GO:0031996 thioesterase binding(GO:0031996)
0.2 0.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 1.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 3.1 GO:0070628 proteasome binding(GO:0070628)
0.1 0.3 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 0.5 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 0.4 GO:0042903 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 0.3 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.1 GO:0046977 TAP binding(GO:0046977)
0.1 0.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 4.5 GO:0005109 frizzled binding(GO:0005109)
0.1 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.8 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.2 GO:0001566 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 1.7 GO:0008009 chemokine activity(GO:0008009)
0.1 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.5 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 1.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.7 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.2 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.0 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.0 0.1 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.0 0.3 GO:0031404 chloride ion binding(GO:0031404)
0.0 1.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 2.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0070330 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 2.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.3 PID IL23 PATHWAY IL23-mediated signaling events
0.1 0.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 4.6 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 0.9 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 3.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 8.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 0.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 3.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis