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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Sox17

Z-value: 0.93

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Transcription factors associated with Sox17

Gene Symbol Gene ID Gene Info
Sox17
ENSMUSG00000025902.7 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox17mm10_v2_chr1_-_4496400_4496420-0.835.1e-10Click!

Activity profile of Sox17 motif

Sorted Z-values of Sox17 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102659213 6.15 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr9_-_48605147 5.83 ENSMUST00000034808.5
ENSMUST00000119426.1
Nnmt
nicotinamide N-methyltransferase
chr8_-_93337195 3.88 ENSMUST00000044602.7
Ces1g
carboxylesterase 1G
chr16_-_18413452 3.25 ENSMUST00000165430.1
ENSMUST00000147720.1
Comt
catechol-O-methyltransferase
chr7_-_100656953 3.24 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr6_-_87690819 2.98 ENSMUST00000162547.1
1810020O05Rik
Riken cDNA 1810020O05 gene
chr8_-_93229517 2.80 ENSMUST00000176282.1
ENSMUST00000034173.7
Ces1e
carboxylesterase 1E
chr8_-_93197799 2.34 ENSMUST00000034172.7
Ces1d
carboxylesterase 1D
chr6_-_128526703 2.21 ENSMUST00000143664.1
ENSMUST00000112132.1
ENSMUST00000032510.7
Pzp
pregnancy zone protein
chr8_+_107150621 2.16 ENSMUST00000034400.3
Cyb5b
cytochrome b5 type B
chr4_+_41903610 1.97 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr4_-_42773993 1.86 ENSMUST00000095114.4
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr5_-_89457763 1.81 ENSMUST00000049209.8
Gc
group specific component
chr3_-_98763053 1.79 ENSMUST00000107019.1
ENSMUST00000107018.1
ENSMUST00000125483.1
ENSMUST00000137008.1
ENSMUST00000135706.1
Hsd3b3
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
chr17_+_46428930 1.71 ENSMUST00000024764.5
ENSMUST00000165993.1
Crip3
cysteine-rich protein 3
chr12_-_84400851 1.68 ENSMUST00000117286.1
Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
chr12_-_84400929 1.68 ENSMUST00000122194.1
Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
chr1_-_162866502 1.63 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr19_-_44107447 1.53 ENSMUST00000119591.1
ENSMUST00000026217.4
Chuk
conserved helix-loop-helix ubiquitous kinase
chr16_+_22951072 1.50 ENSMUST00000023590.8
Hrg
histidine-rich glycoprotein
chr17_+_46428917 1.49 ENSMUST00000113465.3
Crip3
cysteine-rich protein 3
chr8_-_41054771 1.36 ENSMUST00000093534.4
Mtus1
mitochondrial tumor suppressor 1
chr9_+_57521232 1.35 ENSMUST00000000090.6
Cox5a
cytochrome c oxidase subunit Va
chr2_-_180889660 1.31 ENSMUST00000137629.1
Gm14342
predicted gene 14342
chr9_+_50494516 1.27 ENSMUST00000114474.1
1600029D21Rik
RIKEN cDNA 1600029D21 gene
chr5_-_104021799 1.26 ENSMUST00000119025.1
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr11_-_59449913 1.24 ENSMUST00000136436.1
ENSMUST00000150297.1
Snap47
synaptosomal-associated protein, 47
chr2_+_181187247 1.16 ENSMUST00000016488.6
ENSMUST00000108841.1
Ppdpf
pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)RIKEN cDNA 2700038C09 gene
chr6_-_142278836 1.14 ENSMUST00000111825.3
Slco1a5
solute carrier organic anion transporter family, member 1a5
chr17_+_47436615 1.13 ENSMUST00000037701.6
AI661453
expressed sequence AI661453
chr17_+_47436731 1.08 ENSMUST00000150819.2
AI661453
expressed sequence AI661453
chr5_+_90561102 1.08 ENSMUST00000094615.4
5830473C10Rik
RIKEN cDNA 5830473C10 gene
chr7_-_127890918 1.08 ENSMUST00000121394.1
Prss53
protease, serine, 53
chr2_+_80617045 1.03 ENSMUST00000028384.4
Dusp19
dual specificity phosphatase 19
chr7_+_29238434 1.02 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chrX_+_74127463 0.99 ENSMUST00000033771.4
ENSMUST00000101457.3
Opn1mw
opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)
chr9_+_66946057 0.96 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l
ribosomal protein S27-like
chr2_+_18677002 0.95 ENSMUST00000028071.6
Bmi1
Bmi1 polycomb ring finger oncogene
chr11_-_86807624 0.91 ENSMUST00000018569.7
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr7_+_29238323 0.90 ENSMUST00000108238.1
ENSMUST00000032809.3
ENSMUST00000138128.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr6_-_144209471 0.89 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr11_-_77894096 0.86 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr5_-_38502107 0.84 ENSMUST00000005238.6
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr6_-_144209448 0.81 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr9_+_40187079 0.81 ENSMUST00000062229.5
Olfr986
olfactory receptor 986
chr13_+_54071815 0.80 ENSMUST00000021930.8
Sfxn1
sideroflexin 1
chr11_+_104282371 0.80 ENSMUST00000106988.1
ENSMUST00000106989.1
Mapt
microtubule-associated protein tau
chr10_+_80249106 0.79 ENSMUST00000105364.1
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr13_-_35027077 0.79 ENSMUST00000170538.1
ENSMUST00000163280.1
Eci2
enoyl-Coenzyme A delta isomerase 2
chr10_-_128176568 0.76 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr6_-_144209558 0.74 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5
SRY-box containing gene 5
chr18_+_80255227 0.72 ENSMUST00000123750.1
Pqlc1
PQ loop repeat containing 1
chr16_-_23029062 0.66 ENSMUST00000115349.2
Kng2
kininogen 2
chr8_+_117701937 0.65 ENSMUST00000034304.7
Hsd17b2
hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_8470763 0.64 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
Mettl22
methyltransferase like 22
chr7_+_97400003 0.64 ENSMUST00000032882.8
Ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr11_-_110095974 0.63 ENSMUST00000100287.2
Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr5_-_38502079 0.63 ENSMUST00000147664.1
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr10_+_59221945 0.62 ENSMUST00000182161.1
Sowahc
sosondowah ankyrin repeat domain family member C
chr16_-_23029012 0.61 ENSMUST00000039338.6
Kng2
kininogen 2
chr8_-_71676674 0.61 ENSMUST00000066837.4
Gm9933
predicted gene 9933
chr16_-_23029080 0.60 ENSMUST00000100046.2
Kng2
kininogen 2
chr18_-_33213832 0.58 ENSMUST00000025236.2
Stard4
StAR-related lipid transfer (START) domain containing 4
chr19_+_8920358 0.53 ENSMUST00000096243.5
B3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr19_+_34583528 0.52 ENSMUST00000102825.3
Ifit3
interferon-induced protein with tetratricopeptide repeats 3
chr4_-_119173849 0.51 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691
zinc finger protein 691
chr9_+_39993812 0.50 ENSMUST00000057161.3
Olfr978
olfactory receptor 978
chr3_-_58885212 0.50 ENSMUST00000055636.6
ENSMUST00000072551.6
ENSMUST00000051408.7
Clrn1
clarin 1
chr12_-_40199315 0.49 ENSMUST00000095760.2
Lsmem1
leucine-rich single-pass membrane protein 1
chr11_-_110095937 0.45 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr11_+_98646755 0.45 ENSMUST00000093938.3
ENSMUST00000017355.5
Gsdma2
gasdermin A2
chr14_+_73142591 0.44 ENSMUST00000170368.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr7_+_120328660 0.43 ENSMUST00000121265.1
ENSMUST00000076272.3
Abca15
ATP-binding cassette, sub-family A (ABC1), member 15
chr14_-_121698417 0.42 ENSMUST00000040700.7
Dock9
dedicator of cytokinesis 9
chr17_-_40242285 0.42 ENSMUST00000026499.5
Crisp3
cysteine-rich secretory protein 3
chr1_+_178256103 0.42 ENSMUST00000069568.3
Gm9982
predicted gene 9982
chr7_+_102210335 0.42 ENSMUST00000140631.1
ENSMUST00000120879.1
ENSMUST00000146996.1
Pgap2
post-GPI attachment to proteins 2
chr18_+_35599219 0.40 ENSMUST00000115734.1
Paip2
polyadenylate-binding protein-interacting protein 2
chr9_-_49427021 0.39 ENSMUST00000034792.5
Ankk1
ankyrin repeat and kinase domain containing 1
chr10_-_59221757 0.38 ENSMUST00000165971.1
Sept10
septin 10
chr14_+_73142490 0.38 ENSMUST00000170370.1
ENSMUST00000164822.1
ENSMUST00000165429.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr18_-_33213766 0.36 ENSMUST00000119991.1
ENSMUST00000118990.1
Stard4
StAR-related lipid transfer (START) domain containing 4
chr7_+_126976338 0.36 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr2_+_121456963 0.36 ENSMUST00000126764.1
Hypk
huntingtin interacting protein K
chr19_+_6184363 0.35 ENSMUST00000025699.2
ENSMUST00000113528.1
1700123I01Rik
RIKEN cDNA 1700123I01 gene
chr14_+_41072936 0.34 ENSMUST00000161837.1
Dydc1
DPY30 domain containing 1
chr13_-_27668034 0.33 ENSMUST00000006660.5
Prl7a2
prolactin family 7, subfamily a, member 2
chr13_-_74376566 0.32 ENSMUST00000091481.2
Zfp72
zinc finger protein 72
chr19_+_6306456 0.32 ENSMUST00000025681.7
Cdc42bpg
CDC42 binding protein kinase gamma (DMPK-like)
chr4_-_135971894 0.31 ENSMUST00000105852.1
Lypla2
lysophospholipase 2
chr10_-_62362265 0.30 ENSMUST00000149534.1
Hk1
hexokinase 1
chr16_+_23058250 0.29 ENSMUST00000039492.6
ENSMUST00000023589.8
ENSMUST00000089902.6
Kng1
kininogen 1
chr2_+_55411790 0.28 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033
predicted gene 14033
chr5_-_137858034 0.28 ENSMUST00000110978.2
Pilrb1
paired immunoglobin-like type 2 receptor beta 1
chr3_-_88027465 0.28 ENSMUST00000005014.2
Hapln2
hyaluronan and proteoglycan link protein 2
chr8_+_4248188 0.27 ENSMUST00000110993.1
Gm14378
predicted gene 14378
chr10_+_78055327 0.27 ENSMUST00000131825.1
ENSMUST00000139539.1
ENSMUST00000123940.1
Dnmt3l
DNA (cytosine-5-)-methyltransferase 3-like
chr13_+_42301270 0.27 ENSMUST00000021796.7
Edn1
endothelin 1
chr12_+_87973528 0.27 ENSMUST00000110148.2
Gm2046
predicted gene 2046
chr9_+_82829806 0.26 ENSMUST00000113245.2
ENSMUST00000034783.4
Irak1bp1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr5_+_94962962 0.25 ENSMUST00000097488.1
Gm7647
predicted gene 7647
chr4_+_118961578 0.24 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr2_+_52857844 0.24 ENSMUST00000090952.4
ENSMUST00000049483.6
ENSMUST00000050719.6
Fmnl2
formin-like 2
chr7_-_28631067 0.24 ENSMUST00000040112.3
Papl
iron/zinc purple acid phospatase-like
chr14_+_50944499 0.22 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr1_+_171503410 0.22 ENSMUST00000081527.1
Alyref2
Aly/REF export factor 2
chr2_-_76868375 0.21 ENSMUST00000149616.1
ENSMUST00000152185.1
ENSMUST00000130915.1
ENSMUST00000155365.1
ENSMUST00000128071.1
Ttn
titin
chr9_+_110834588 0.19 ENSMUST00000146794.1
ENSMUST00000011391.7
Prss45
protease, serine, 45
chr2_-_57113053 0.18 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr2_-_121456693 0.18 ENSMUST00000110613.2
ENSMUST00000056312.3
Serinc4
serine incorporator 4
chr7_+_99735145 0.18 ENSMUST00000098264.1
Olfr520
olfactory receptor 520
chr2_-_34826187 0.18 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2
F-box and WD-40 domain protein 2
chr5_+_94624013 0.17 ENSMUST00000098286.3
Gm6509
predicted gene 6509
chr5_-_130002838 0.17 ENSMUST00000111308.1
ENSMUST00000111307.1
Gusb
glucuronidase, beta
chr13_+_33484784 0.15 ENSMUST00000081927.2
Serpinb9g
serine (or cysteine) peptidase inhibitor, clade B, member 9g
chr13_+_23162643 0.15 ENSMUST00000076180.1
Vmn1r219
vomeronasal 1 receptor 219
chrX_-_48877711 0.14 ENSMUST00000114928.1
Gm595
predicted gene 595
chr15_-_96460838 0.13 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chr3_+_92432578 0.12 ENSMUST00000067102.2
Sprr2k
small proline-rich protein 2K
chr9_-_35790101 0.12 ENSMUST00000034619.1
D730048I06Rik
RIKEN cDNA D730048I06 gene
chr14_+_64104286 0.12 ENSMUST00000022537.5
Prss52
protease, serine, 52
chr9_+_108392820 0.09 ENSMUST00000035234.4
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr12_+_84970897 0.07 ENSMUST00000021669.8
ENSMUST00000171040.1
Fcf1
FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr17_+_47759175 0.05 ENSMUST00000125177.1
Tfeb
transcription factor EB
chr3_+_92352141 0.03 ENSMUST00000068399.1
Sprr2e
small proline-rich protein 2E
chr7_-_104353328 0.01 ENSMUST00000130139.1
ENSMUST00000059037.8
Trim12c
tripartite motif-containing 12C
chr2_-_142901506 0.01 ENSMUST00000043589.7
Kif16b
kinesin family member 16B

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.9 6.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.8 2.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.6 1.9 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.5 1.5 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.5 0.9 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
0.4 3.9 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.3 1.3 GO:0006710 androgen catabolic process(GO:0006710)
0.3 0.9 GO:0006553 lysine metabolic process(GO:0006553)
0.3 2.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 1.0 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2 1.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 1.5 GO:1902739 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 1.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 3.4 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.1 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.5 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 1.7 GO:0046415 urate metabolic process(GO:0046415)
0.1 1.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.8 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 1.0 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 1.2 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.2 GO:0043056 forward locomotion(GO:0043056)
0.1 0.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 1.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.3 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 2.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 2.2 GO:0007566 embryo implantation(GO:0007566)
0.0 0.8 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 1.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.8 GO:0006826 iron ion transport(GO:0006826)
0.0 5.6 GO:0032259 methylation(GO:0032259)
0.0 0.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.3 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 2.6 GO:0042098 T cell proliferation(GO:0042098)
0.0 1.8 GO:0006694 steroid biosynthetic process(GO:0006694)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0032010 phagolysosome(GO:0032010)
0.2 7.0 GO:0030673 axolemma(GO:0030673)
0.1 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 4.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 4.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 2.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
1.0 6.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.8 2.3 GO:0004771 sterol esterase activity(GO:0004771)
0.7 3.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.5 1.5 GO:1902271 D3 vitamins binding(GO:1902271)
0.3 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 2.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 1.8 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.9 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 1.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 1.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 1.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.0 GO:0008494 translation activator activity(GO:0008494)
0.1 1.0 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 6.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 1.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 3.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 3.7 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.2 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.5 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 3.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME OPSINS Genes involved in Opsins
0.1 1.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 9.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 6.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 2.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis