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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tbx21

Z-value: 1.83

Motif logo

Transcription factors associated with Tbx21

Gene Symbol Gene ID Gene Info
ENSMUSG00000001444.2 T-box 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx21mm10_v2_chr11_-_97115327_971153320.353.7e-02Click!

Activity profile of Tbx21 motif

Sorted Z-values of Tbx21 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_4874341 16.69 ENSMUST00000137337.1
ENSMUST00000045921.7
major facilitator superfamily domain containing 2B
chr16_-_36408349 13.47 ENSMUST00000023619.6
stefin A2
chr9_+_110419750 13.09 ENSMUST00000035061.6
neutrophilic granule protein
chr11_+_24080664 8.05 ENSMUST00000118955.1
B cell CLL/lymphoma 11A (zinc finger protein)
chr17_+_48247759 7.66 ENSMUST00000048065.5
triggering receptor expressed on myeloid cells 3
chr7_-_127042420 6.33 ENSMUST00000032915.6
kinesin family member 22
chr7_+_18884679 6.21 ENSMUST00000032573.6
peptidoglycan recognition protein 1
chr7_+_128062657 5.56 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
integrin alpha M
chr7_-_126704816 5.50 ENSMUST00000032949.7
coronin, actin binding protein 1A
chr11_+_116531097 5.45 ENSMUST00000138840.1
sphingosine kinase 1
chr4_+_154869585 5.33 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
membrane metallo-endopeptidase-like 1
chr6_-_60829826 4.85 ENSMUST00000163779.1
synuclein, alpha
chr7_+_35449154 4.71 ENSMUST00000032703.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr15_+_99074968 4.66 ENSMUST00000039665.6
trophinin associated protein
chr7_+_35449035 4.59 ENSMUST00000118969.1
ENSMUST00000118383.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr11_+_120608469 4.22 ENSMUST00000106194.1
ENSMUST00000106195.2
neuropeptide B
chr7_+_128062698 4.14 ENSMUST00000119696.1
integrin alpha M
chr19_+_58759700 3.86 ENSMUST00000026081.3
pancreatic lipase-related protein 2
chr5_-_138170992 3.76 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_+_128062635 3.69 ENSMUST00000064821.7
ENSMUST00000106242.3
integrin alpha M
chr15_+_74714832 3.61 ENSMUST00000023265.3
prostate stem cell antigen
chr7_+_13278778 3.56 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
ligase I, DNA, ATP-dependent
chr11_+_120608492 3.56 ENSMUST00000061309.4
neuropeptide B
chr6_+_90619241 3.25 ENSMUST00000032177.8
solute carrier family 41, member 3
chr2_-_164356507 3.21 ENSMUST00000109367.3
secretory leukocyte peptidase inhibitor
chr16_-_4003750 3.21 ENSMUST00000171658.1
ENSMUST00000171762.1
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr13_-_49248663 3.16 ENSMUST00000135784.1
ENSMUST00000021816.5
sushi domain containing 3
chr13_+_21945084 3.09 ENSMUST00000176511.1
ENSMUST00000102978.1
ENSMUST00000152258.2
zinc finger protein 184 (Kruppel-like)
chr10_+_77530252 3.02 ENSMUST00000000299.7
ENSMUST00000131023.1
ENSMUST00000130059.1
integrin beta 2
chr17_+_35861318 2.96 ENSMUST00000074259.8
ENSMUST00000174873.1
nurim (nuclear envelope membrane protein)
chr12_-_87233556 2.88 ENSMUST00000021423.7
NADP+ dependent oxidoreductase domain containing 1
chr11_-_74590186 2.59 ENSMUST00000102521.1
RAP1 GTPase activating protein 2
chr4_+_115563649 2.59 ENSMUST00000141033.1
ENSMUST00000030486.8
ENSMUST00000126645.1
ENSMUST00000030480.3
cytochrome P450, family 4, subfamily a, polypeptide 31
chr11_+_103171081 2.54 ENSMUST00000042286.5
formin-like 1
chr1_-_80758536 2.53 ENSMUST00000077946.5
dedicator of cytokinesis 10
chr14_-_56234650 2.47 ENSMUST00000015585.2
granzyme C
chr11_-_74590065 2.47 ENSMUST00000145524.1
ENSMUST00000047488.7
RAP1 GTPase activating protein 2
chr2_-_51934644 2.38 ENSMUST00000165313.1
RNA binding motif protein 43
chr11_-_120643643 2.31 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
pyrroline-5-carboxylate reductase 1
chr16_-_20425881 2.29 ENSMUST00000077867.3
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_-_119459266 2.29 ENSMUST00000033255.5
glycoprotein 2 (zymogen granule membrane)
chr13_+_113317084 2.24 ENSMUST00000136755.2
cDNA sequence BC067074
chr5_-_24730635 2.22 ENSMUST00000068693.5
WD repeat domain 86
chr5_-_120777628 2.19 ENSMUST00000044833.8
2'-5' oligoadenylate synthetase 3
chr9_-_112185726 2.18 ENSMUST00000160240.1
ENSMUST00000162065.1
cyclic AMP-regulated phosphoprotein, 21
chr6_+_36388055 2.11 ENSMUST00000172278.1
cholinergic receptor, muscarinic 2, cardiac
chr7_+_126861947 2.09 ENSMUST00000037248.3
HIRA interacting protein 3
chr16_-_20426322 2.03 ENSMUST00000115547.2
ENSMUST00000096199.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr19_+_34192229 2.00 ENSMUST00000054956.8
STAM binding protein like 1
chr2_-_62573905 2.00 ENSMUST00000102732.3
fibroblast activation protein
chr17_-_24527925 1.94 ENSMUST00000176652.1
TNF receptor-associated factor 7
chr8_-_92356103 1.92 ENSMUST00000034183.3
RIKEN cDNA 4933436C20 gene
chr17_-_24527830 1.90 ENSMUST00000176353.1
ENSMUST00000176237.1
TNF receptor-associated factor 7
chr8_+_12984246 1.90 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
mcf.2 transforming sequence-like
chr1_+_34801704 1.83 ENSMUST00000047664.9
Rho guanine nucleotide exchange factor (GEF) 4
chr1_+_91351016 1.67 ENSMUST00000027533.8
kelch-like 30
chr4_-_117156144 1.64 ENSMUST00000102696.4
ribosomal protein S8
chr9_-_112185939 1.63 ENSMUST00000070218.5
cyclic AMP-regulated phosphoprotein, 21
chr10_+_62252325 1.61 ENSMUST00000020278.5
tachykinin receptor 2
chr1_+_74153981 1.61 ENSMUST00000027372.7
ENSMUST00000106899.2
chemokine (C-X-C motif) receptor 2
chr6_-_50261943 1.58 ENSMUST00000167893.1
deafness, autosomal dominant 5 (human)
chr9_-_35558522 1.57 ENSMUST00000034612.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr12_+_73286868 1.52 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
solute carrier family 38, member 6
chr4_-_132353605 1.51 ENSMUST00000155129.1
regulator of chromosome condensation 1
chr4_+_132564051 1.50 ENSMUST00000070690.7
platelet-activating factor receptor
chr3_-_127499095 1.46 ENSMUST00000182594.1
ankyrin 2, brain
chr16_-_36131156 1.44 ENSMUST00000161638.1
ENSMUST00000096090.2
cystatin A
chr11_+_108682602 1.42 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
centrosomal protein 112
chrX_+_170009659 1.37 ENSMUST00000179760.1
predicted gene, 21887
chr14_-_54517353 1.34 ENSMUST00000023873.5
protein arginine N-methyltransferase 5
chr7_-_25412857 1.32 ENSMUST00000074040.3
chemokine (C-X-C motif) ligand 17
chr17_-_25941926 1.32 ENSMUST00000139226.1
ENSMUST00000097368.3
ENSMUST00000026823.8
phosphatidylinositol glycan anchor biosynthesis, class Q
chr5_-_149051300 1.32 ENSMUST00000110505.1
high mobility group box 1
chr7_+_4337710 1.23 ENSMUST00000006792.4
natural cytotoxicity triggering receptor 1
chr19_-_6128208 1.23 ENSMUST00000025702.7
sorting nexin 15
chr8_-_13254154 1.22 ENSMUST00000033825.4
ADP-ribosylhydrolase like 1
chr6_-_38124568 1.18 ENSMUST00000040259.4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr8_+_25849618 1.17 ENSMUST00000098858.3
potassium channel, subfamily U, member 1
chr18_-_78057395 1.14 ENSMUST00000170760.2
sialic acid binding Ig-like lectin 15
chr11_-_61719946 1.13 ENSMUST00000151780.1
ENSMUST00000148584.1
solute carrier family 5 (sodium/glucose cotransporter), member 10
chr15_+_34495302 1.10 ENSMUST00000052290.7
ENSMUST00000079028.5
processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
chr6_+_129397478 1.08 ENSMUST00000112081.2
ENSMUST00000112079.2
C-type lectin domain family 1, member b
chr14_+_56017964 1.06 ENSMUST00000022836.4
mast cell protease 1
chr6_-_34955903 1.01 ENSMUST00000147169.1
RIKEN cDNA 2010107G12 gene
chr14_+_24293214 0.99 ENSMUST00000162224.1
ENSMUST00000163055.1
ENSMUST00000161740.1
ENSMUST00000160710.1
ENSMUST00000041413.5
RIKEN cDNA E330034G19 gene
chr5_-_5663263 0.99 ENSMUST00000148193.1
RIKEN cDNA A330021E22 gene
chr8_+_40423786 0.99 ENSMUST00000049389.4
ENSMUST00000128166.1
ENSMUST00000167766.1
zinc finger, DHHC domain containing 2
chr11_-_121039400 0.98 ENSMUST00000026159.5
CD7 antigen
chr9_+_59291565 0.98 ENSMUST00000026266.7
ADP-dependent glucokinase
chr3_-_54735001 0.97 ENSMUST00000153224.1
exosome component 8
chr14_+_53709902 0.97 ENSMUST00000103638.4
T cell receptor alpha variable 6-7-DV9
chr7_-_126861648 0.97 ENSMUST00000129812.1
ENSMUST00000106342.1
INO80 complex subunit E
chr8_+_81342556 0.96 ENSMUST00000172167.1
ENSMUST00000169116.1
ENSMUST00000109852.2
ENSMUST00000172031.1
inositol polyphosphate-4-phosphatase, type II
chr10_-_13868932 0.95 ENSMUST00000019942.5
ENSMUST00000162610.1
androgen-induced 1
chr8_+_95633500 0.92 ENSMUST00000034094.9
GINS complex subunit 3 (Psf3 homolog)
chr2_-_151973387 0.90 ENSMUST00000109863.1
family with sequence similarity 110, member A
chr9_+_31386187 0.89 ENSMUST00000086167.5
nuclear factor related to kappa B binding protein
chr6_-_52183828 0.88 ENSMUST00000134831.1
homeobox A3
chr1_-_97661668 0.87 ENSMUST00000153115.1
ENSMUST00000142234.1
DNA segment, Chr 1, ERATO Doi 622, expressed
chr15_+_82298943 0.86 ENSMUST00000023089.3
WBP2 N-terminal like
chr2_+_3118335 0.85 ENSMUST00000115099.2
family with sequence similarity 171, member A1
chr7_-_126861828 0.84 ENSMUST00000106343.1
INO80 complex subunit E
chr4_+_132638987 0.83 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
eyes absent 3 homolog (Drosophila)
chr2_+_158512796 0.80 ENSMUST00000099133.3
ENSMUST00000165398.1
Rho GTPase activating protein 40
chr14_+_103513328 0.80 ENSMUST00000095576.3
sciellin
chr15_+_54410755 0.79 ENSMUST00000036737.3
collectin sub-family member 10
chr11_-_70656467 0.77 ENSMUST00000131642.1
predicted gene 12319
chr11_-_45955465 0.77 ENSMUST00000011398.6
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr1_+_153652943 0.70 ENSMUST00000041776.5
regulator of G-protein signaling 8
chr10_-_13868779 0.67 ENSMUST00000105534.3
androgen-induced 1
chr17_+_6270475 0.67 ENSMUST00000088940.4
transmembrane protein 181A
chr15_+_75616675 0.65 ENSMUST00000161785.1
ENSMUST00000054555.8
ENSMUST00000161752.1
zinc finger protein 41
chr13_+_104178797 0.63 ENSMUST00000022225.5
ENSMUST00000069187.5
tripartite motif-containing 23
chr17_-_33713372 0.63 ENSMUST00000173392.1
membrane-associated ring finger (C3HC4) 2
chr11_-_65162904 0.60 ENSMUST00000093002.5
ENSMUST00000047463.8
Rho GTPase activating protein 44
chr2_+_3118523 0.60 ENSMUST00000062934.6
family with sequence similarity 171, member A1
chr17_+_24728174 0.60 ENSMUST00000183214.1
ribosomal protein L3-like
chr5_-_149053038 0.60 ENSMUST00000085546.6
high mobility group box 1
chr6_+_129397297 0.60 ENSMUST00000032262.7
C-type lectin domain family 1, member b
chr3_+_137918526 0.59 ENSMUST00000168345.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr2_+_3118407 0.58 ENSMUST00000091505.4
family with sequence similarity 171, member A1
chr1_-_16104163 0.55 ENSMUST00000149566.1
ribosomal protein L7
chr1_+_179546303 0.54 ENSMUST00000040706.8
consortin, connexin sorting protein
chr5_-_39644597 0.51 ENSMUST00000152057.1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr8_-_68735058 0.51 ENSMUST00000136060.1
ENSMUST00000130214.1
ENSMUST00000078350.6
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr13_-_100108337 0.50 ENSMUST00000180822.1
cDNA sequence BC001981
chr2_-_152540094 0.49 ENSMUST00000060598.3
defensin beta 29
chr14_+_54426902 0.48 ENSMUST00000010550.7
mitochondrial ribosomal protein L52
chrX_+_74254782 0.46 ENSMUST00000119197.1
ENSMUST00000088313.4
emerin
chr19_-_60226666 0.46 ENSMUST00000065286.1
DNA segment, Chr 19, ERATO Doi 737, expressed
chr7_+_19149722 0.46 ENSMUST00000049294.2
small nuclear ribonucleoprotein D2
chr11_-_78751656 0.45 ENSMUST00000059468.4
family with sequence similarity 58, member B
chr17_+_84511832 0.45 ENSMUST00000047206.5
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr5_-_36582381 0.43 ENSMUST00000141043.1
ENSMUST00000031094.8
TBC1 domain family, member 14
chr18_-_42579652 0.41 ENSMUST00000054738.3
G protein-coupled receptor 151
chr1_+_85100164 0.38 ENSMUST00000097669.1
predicted gene 10553
chr16_+_75592844 0.36 ENSMUST00000114249.1
ENSMUST00000046378.7
ENSMUST00000114253.1
RNA binding motif protein 11
chr5_-_39644634 0.35 ENSMUST00000053116.6
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr1_+_59912972 0.32 ENSMUST00000036540.5
family with sequence similarity 117, member B
chr10_-_75560330 0.30 ENSMUST00000051129.9
family with sequence similarity 211, member B
chr15_-_63835949 0.29 ENSMUST00000089900.3
gasdermin C2
chr17_-_27029009 0.29 ENSMUST00000078691.5
BCL2-antagonist/killer 1
chr11_-_6267718 0.28 ENSMUST00000004507.4
ENSMUST00000151446.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
chr9_-_117252450 0.28 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
RNA binding motif, single stranded interacting protein
chr1_-_133131782 0.26 ENSMUST00000180528.1
predicted gene, 26616
chr7_-_27178835 0.26 ENSMUST00000093040.6
RAB4B, member RAS oncogene family
chr7_+_141078188 0.26 ENSMUST00000106039.2
plakophilin 3
chr8_-_13254068 0.26 ENSMUST00000168498.1
ADP-ribosylhydrolase like 1
chr7_+_140247316 0.25 ENSMUST00000164583.1
ENSMUST00000093984.2
RIKEN cDNA 5830411N06 gene
chr19_-_5610038 0.24 ENSMUST00000113641.2
K(lysine) acetyltransferase 5
chr12_-_102439813 0.24 ENSMUST00000021607.8
legumain
chr4_-_88868379 0.22 ENSMUST00000057837.1
RIKEN cDNA 4930553M12 gene
chr18_+_37742088 0.22 ENSMUST00000003599.6
protocadherin gamma subfamily A, 9
chr10_+_7792891 0.21 ENSMUST00000015901.4
peptidylprolyl isomerase (cyclophilin)-like 4
chr10_+_80292453 0.21 ENSMUST00000068408.7
ENSMUST00000062674.6
ribosomal protein S15
chr13_+_100669481 0.21 ENSMUST00000057325.7
ENSMUST00000170347.2
coiled-coil domain containing 125
chr1_-_152090308 0.20 ENSMUST00000044581.7
RIKEN cDNA 1700025G04 gene
chr2_-_151973840 0.18 ENSMUST00000109865.1
ENSMUST00000109864.1
family with sequence similarity 110, member A
chr13_+_98279892 0.18 ENSMUST00000178658.1
ENSMUST00000180066.1
predicted gene 21976
chr8_-_105701077 0.17 ENSMUST00000042608.6
adrenocortical dysplasia
chrX_-_95444789 0.17 ENSMUST00000084535.5
APC membrane recruitment 1
chr18_-_37997543 0.16 ENSMUST00000042944.7
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr13_+_56609516 0.15 ENSMUST00000045173.8
transforming growth factor, beta induced
chrY_-_84489780 0.14 ENSMUST00000179727.1
predicted gene, 21782
chr11_-_71230733 0.13 ENSMUST00000108516.2
NLR family, pyrin domain containing 1B
chr8_-_13254096 0.12 ENSMUST00000171619.1
ADP-ribosylhydrolase like 1
chr14_-_51050163 0.12 ENSMUST00000076106.3
ribonuclease, RNase A family, 11 (non-active)
chr19_+_5425121 0.12 ENSMUST00000159759.1
expressed sequence AI837181
chr18_+_37020097 0.12 ENSMUST00000047614.1
protocadherin alpha 2
chr14_-_66077694 0.12 ENSMUST00000022618.5
a disintegrin and metallopeptidase domain 2
chr3_+_59952185 0.12 ENSMUST00000094227.3
predicted gene 9696
chr9_+_57148180 0.11 ENSMUST00000105102.2
predicted gene 16493
chr7_+_45785331 0.09 ENSMUST00000120005.1
ENSMUST00000123585.1
lemur tyrosine kinase 3
chr4_+_109000770 0.08 ENSMUST00000106644.2
nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr13_-_36117269 0.07 ENSMUST00000053265.6
LYR motif containing 4
chr10_+_116966274 0.06 ENSMUST00000033651.3
RIKEN cDNA D630029K05 gene
chr9_-_106656081 0.04 ENSMUST00000023959.7
glutamate receptor, metabotropic 2
chr16_-_92359424 0.03 ENSMUST00000051705.5
potassium voltage-gated channel, Isk-related subfamily, member 1
chr19_+_12599953 0.01 ENSMUST00000181868.1
ENSMUST00000092931.6
predicted gene 4952
chr4_+_155086577 0.01 ENSMUST00000030915.4
ENSMUST00000155775.1
ENSMUST00000127457.1
MORN repeat containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
3.1 9.3 GO:0015811 L-cystine transport(GO:0015811)
2.1 6.2 GO:0051710 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
2.0 8.0 GO:1904799 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
1.9 13.4 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
1.6 4.8 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
1.1 7.7 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.1 3.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.9 5.5 GO:0032796 uropod organization(GO:0032796)
0.9 5.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.7 5.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.7 2.0 GO:0010710 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.6 1.9 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.5 3.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.5 2.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.5 2.3 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.4 2.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.4 1.6 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.4 3.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 1.5 GO:1904306 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.3 2.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.3 1.6 GO:0014055 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) operant conditioning(GO:0035106)
0.3 3.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 2.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.3 1.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 1.2 GO:0009597 detection of virus(GO:0009597)
0.2 2.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 1.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 3.9 GO:0006968 cellular defense response(GO:0006968) galactolipid metabolic process(GO:0019374) glycolipid catabolic process(GO:0019377)
0.2 2.5 GO:0051014 actin filament severing(GO:0051014)
0.2 0.5 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 3.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 1.5 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.9 GO:0010159 specification of organ position(GO:0010159)
0.1 5.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 7.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 0.6 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 1.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.8 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0002352 B cell negative selection(GO:0002352)
0.1 0.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 3.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.9 GO:0010764 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 1.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.8 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 1.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 0.4 GO:0009405 pathogenesis(GO:0009405)
0.1 3.6 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.1 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 1.7 GO:0030220 platelet formation(GO:0030220)
0.1 1.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.0 1.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 3.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.0 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 6.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 1.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 1.0 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 1.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 3.4 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 1.2 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 4.4 GO:0015711 organic anion transport(GO:0015711)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.8 3.0 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.6 3.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 2.0 GO:0071438 invadopodium membrane(GO:0071438)
0.3 13.4 GO:0008305 integrin complex(GO:0008305)
0.3 3.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 3.8 GO:0042555 MCM complex(GO:0042555)
0.2 5.5 GO:0032426 stereocilium tip(GO:0032426)
0.2 3.4 GO:0005652 nuclear lamina(GO:0005652)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 2.7 GO:0031011 Ino80 complex(GO:0031011)
0.2 1.8 GO:0034709 methylosome(GO:0034709)
0.1 1.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.6 GO:0042629 mast cell granule(GO:0042629)
0.1 0.6 GO:0071986 Ragulator complex(GO:0071986)
0.1 6.3 GO:0005871 kinesin complex(GO:0005871)
0.1 1.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.6 GO:0033391 chromatoid body(GO:0033391)
0.1 9.3 GO:0031526 brush border membrane(GO:0031526)
0.1 0.3 GO:0005914 spot adherens junction(GO:0005914)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.5 GO:0031430 M band(GO:0031430)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 8.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 5.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.6 GO:0031672 A band(GO:0031672)
0.0 6.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.5 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.9 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 16.9 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 2.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.4 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
2.3 16.4 GO:0001851 complement component C3b binding(GO:0001851)
1.3 5.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
1.2 6.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
1.1 7.7 GO:0042834 peptidoglycan binding(GO:0042834)
0.8 5.5 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.6 3.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.6 1.9 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.5 1.6 GO:0004995 tachykinin receptor activity(GO:0004995)
0.5 1.6 GO:0019959 interleukin-8 binding(GO:0019959)
0.5 4.8 GO:1903136 cuprous ion binding(GO:1903136)
0.4 2.6 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.4 2.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 1.6 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.4 3.6 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4 1.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 1.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 1.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 1.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 25.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 3.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 0.8 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 1.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.3 5.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 1.0 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 2.5 GO:0005522 profilin binding(GO:0005522)
0.2 2.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.5 GO:0047238 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 3.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 3.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 6.3 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 5.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 8.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 1.3 GO:0008009 chemokine activity(GO:0008009)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 4.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 7.5 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 7.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 1.9 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 3.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 16.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 5.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 4.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.4 PID ATR PATHWAY ATR signaling pathway
0.1 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 4.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 3.6 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.2 3.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 6.3 REACTOME KINESINS Genes involved in Kinesins
0.2 16.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 5.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 5.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 5.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.9 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 3.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 10.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 2.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.5 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases