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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Zic3

Z-value: 0.96

Motif logo

Transcription factors associated with Zic3

Gene Symbol Gene ID Gene Info
ENSMUSG00000067860.5 zinc finger protein of the cerebellum 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zic3mm10_v2_chrX_+_58030622_580306430.382.2e-02Click!

Activity profile of Zic3 motif

Sorted Z-values of Zic3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_24370255 3.83 ENSMUST00000171904.1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr18_-_78142119 3.64 ENSMUST00000160639.1
solute carrier family 14 (urea transporter), member 1
chr12_-_76709997 3.41 ENSMUST00000166101.1
spectrin beta, erythrocytic
chrX_+_73639414 3.25 ENSMUST00000019701.8
dual specificity phosphatase 9
chr11_+_115899943 3.17 ENSMUST00000152171.1
small integral membrane protein 5
chr11_+_115900125 2.94 ENSMUST00000142089.1
ENSMUST00000131566.1
small integral membrane protein 5
chr11_+_72999069 2.64 ENSMUST00000021141.7
purinergic receptor P2X, ligand-gated ion channel, 1
chr7_-_17062384 2.61 ENSMUST00000153833.1
ENSMUST00000108492.2
hypoxia inducible factor 3, alpha subunit
chr2_-_170427828 2.36 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
breast carcinoma amplified sequence 1
chr8_+_94329192 2.17 ENSMUST00000034218.3
solute carrier family 12, member 3
chr13_+_44729535 2.10 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chr9_-_103480328 1.94 ENSMUST00000124310.2
beaded filament structural protein 2, phakinin
chr5_+_137288273 1.92 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chrX_+_56454871 1.89 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr7_+_110773658 1.85 ENSMUST00000143786.1
adenosine monophosphate deaminase 3
chr9_-_123678873 1.79 ENSMUST00000040960.6
solute carrier family 6 (neurotransmitter transporter), member 20A
chr9_-_123678782 1.76 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr10_+_82985473 1.68 ENSMUST00000040110.7
carbohydrate sulfotransferase 11
chr8_-_85365317 1.64 ENSMUST00000034133.7
myosin light chain kinase 3
chr8_-_85365341 1.64 ENSMUST00000121972.1
myosin light chain kinase 3
chrX_-_49788204 1.59 ENSMUST00000114893.1
immunoglobulin superfamily, member 1
chr6_+_87778084 1.55 ENSMUST00000032133.3
glycoprotein 9 (platelet)
chr17_+_25366550 1.51 ENSMUST00000069616.7
tryptase beta 2
chr4_-_118620763 1.51 ENSMUST00000071972.4
WD repeat domain 65
chr6_-_52218686 1.46 ENSMUST00000134367.2
homeobox A7
chr5_+_66676098 1.45 ENSMUST00000031131.9
ubiquitin carboxy-terminal hydrolase L1
chr6_+_90619241 1.33 ENSMUST00000032177.8
solute carrier family 41, member 3
chr1_-_133801031 1.32 ENSMUST00000143567.1
ATPase, Ca++ transporting, plasma membrane 4
chr5_-_136883115 1.31 ENSMUST00000057497.6
ENSMUST00000111103.1
collagen, type XXVI, alpha 1
chr8_-_18950932 1.31 ENSMUST00000055503.5
ENSMUST00000095438.3
X Kell blood group precursor-related family, member 5
chr9_-_44454757 1.26 ENSMUST00000047740.2
uroplakin 2
chr7_+_96211656 1.23 ENSMUST00000107165.1
teneurin transmembrane protein 4
chr12_+_81631369 1.23 ENSMUST00000036116.5
tetratricopeptide repeat domain 9
chr7_+_78914216 1.20 ENSMUST00000120331.2
interferon-stimulated protein
chr2_-_92371039 1.19 ENSMUST00000068586.6
glycosyltransferase-like 1B
chr2_-_151009364 1.19 ENSMUST00000109896.1
ninein-like
chr4_+_141010644 1.14 ENSMUST00000071977.8
microfibrillar-associated protein 2
chr7_-_110982443 1.12 ENSMUST00000005751.6
MRV integration site 1
chr5_-_107726017 1.11 ENSMUST00000159263.2
growth factor independent 1
chr4_+_52439235 1.10 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
structural maintenance of chromosomes 2
chr7_+_30787897 1.09 ENSMUST00000098559.1
keratinocyte differentiation associated protein
chr18_-_62179948 1.08 ENSMUST00000053640.3
adrenergic receptor, beta 2
chr8_-_25101734 1.08 ENSMUST00000098866.4
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr13_-_47105790 1.07 ENSMUST00000129352.1
DEK oncogene (DNA binding)
chr10_-_128401218 1.05 ENSMUST00000042666.5
solute carrier family 39 (metal ion transporter), member 5
chr9_-_110645328 1.05 ENSMUST00000149089.1
neurobeachin-like 2
chr5_-_138170992 1.05 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_-_92370999 1.05 ENSMUST00000176810.1
ENSMUST00000090582.4
glycosyltransferase-like 1B
chr3_+_19644452 1.04 ENSMUST00000029139.7
tripartite motif-containing 55
chr17_-_68004075 1.01 ENSMUST00000024840.5
Rho GTPase activating protein 28
chrX_+_37048807 1.01 ENSMUST00000060057.1
sosondowah ankyrin repeat domain family member D
chr6_-_86669136 1.00 ENSMUST00000001184.7
MAX dimerization protein 1
chrX_+_72987339 1.00 ENSMUST00000164800.1
ENSMUST00000114546.2
zinc finger protein 185
chr4_-_136956784 0.99 ENSMUST00000030420.8
Eph receptor A8
chr3_-_100489324 0.99 ENSMUST00000061455.8
family with sequence similarity 46, member C
chr1_+_75507077 0.97 ENSMUST00000037330.4
inhibin alpha
chr17_-_71310952 0.96 ENSMUST00000024849.9
elastin microfibril interfacer 2
chr14_-_73325773 0.96 ENSMUST00000022701.6
retinoblastoma 1
chr11_+_87760533 0.95 ENSMUST00000039627.5
ENSMUST00000100644.3
benzodiazepine receptor associated protein 1
chr1_+_91366412 0.95 ENSMUST00000086861.5
family with sequence similarity 132, member B
chr9_-_32344237 0.95 ENSMUST00000034533.5
potassium inwardly-rectifying channel, subfamily J, member 5
chr9_-_44251464 0.92 ENSMUST00000034618.4
PDZ domain containing 3
chr2_-_92370968 0.91 ENSMUST00000176774.1
glycosyltransferase-like 1B
chr14_+_25607797 0.91 ENSMUST00000160229.1
zinc finger, MIZ-type containing 1
chr12_+_83763628 0.91 ENSMUST00000121733.1
papilin, proteoglycan-like sulfated glycoprotein
chr12_+_83763654 0.91 ENSMUST00000021646.5
papilin, proteoglycan-like sulfated glycoprotein
chr7_+_43427622 0.90 ENSMUST00000177164.2
lens intrinsic membrane protein 2
chr19_-_5726240 0.90 ENSMUST00000049295.8
ENSMUST00000075606.4
EH domain binding protein 1-like 1
chr15_-_58324161 0.88 ENSMUST00000022985.1
kelch-like 38
chr11_+_67078293 0.87 ENSMUST00000108689.1
ENSMUST00000165221.1
ENSMUST00000007301.7
myosin, heavy polypeptide 3, skeletal muscle, embryonic
chr19_-_4615453 0.87 ENSMUST00000053597.2
leucine rich repeat and fibronectin type III domain containing 4
chr11_-_109472611 0.87 ENSMUST00000168740.1
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr2_+_103424820 0.87 ENSMUST00000126290.1
E74-like factor 5
chr17_+_86963279 0.86 ENSMUST00000139344.1
ras homolog gene family, member Q
chr11_+_53519871 0.86 ENSMUST00000120878.2
septin 8
chr3_-_53657339 0.86 ENSMUST00000091137.4
Fras1 related extracellular matrix protein 2
chr14_+_54476100 0.85 ENSMUST00000164766.1
ENSMUST00000164697.1
rad and gem related GTP binding protein 2
chr2_+_120629113 0.85 ENSMUST00000150912.1
ENSMUST00000180041.1
START domain containing 9
chr11_-_118103492 0.84 ENSMUST00000132685.1
dynein, axonemal, heavy chain 17
chr8_-_122460666 0.84 ENSMUST00000006762.5
snail homolog 3 (Drosophila)
chr11_+_53519920 0.84 ENSMUST00000147912.1
septin 8
chr8_+_70501116 0.83 ENSMUST00000127983.1
cytokine receptor-like factor 1
chr9_-_53975246 0.83 ENSMUST00000048409.7
ELMO/CED-12 domain containing 1
chr11_+_3332426 0.82 ENSMUST00000136474.1
phosphoinositide-3-kinase interacting protein 1
chr8_+_93810832 0.81 ENSMUST00000034198.8
ENSMUST00000125716.1
guanine nucleotide binding protein, alpha O
chr1_-_119053339 0.81 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
GLI-Kruppel family member GLI2
chr16_+_37011758 0.80 ENSMUST00000071452.5
ENSMUST00000054034.6
polymerase (DNA directed), theta
chr16_-_91011029 0.80 ENSMUST00000130813.1
synaptojanin 1
chr6_-_87981482 0.79 ENSMUST00000056403.5
H1 histone family, member X
chr7_-_126704736 0.79 ENSMUST00000131415.1
coronin, actin binding protein 1A
chr5_+_137758133 0.79 ENSMUST00000141733.1
ENSMUST00000110985.1
TSC22 domain family, member 4
chr10_-_81378459 0.79 ENSMUST00000140901.1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr2_+_91035613 0.79 ENSMUST00000111445.3
ENSMUST00000111446.3
ENSMUST00000050323.5
receptor-associated protein of the synapse
chr7_+_130865835 0.78 ENSMUST00000075181.4
ENSMUST00000048180.5
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr12_+_3806513 0.78 ENSMUST00000172719.1
DNA methyltransferase 3A
chr7_-_126704816 0.78 ENSMUST00000032949.7
coronin, actin binding protein 1A
chr6_+_86404336 0.78 ENSMUST00000113713.2
ENSMUST00000113708.1
cytotoxic granule-associated RNA binding protein 1
chr17_+_35135463 0.77 ENSMUST00000173535.1
ENSMUST00000173952.1
BCL2-associated athanogene 6
chr2_+_29889720 0.77 ENSMUST00000113767.1
outer dense fiber of sperm tails 2
chr15_-_94404258 0.77 ENSMUST00000035342.4
ENSMUST00000155907.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
chr11_+_72042455 0.77 ENSMUST00000021164.3
family with sequence similarity 64, member A
chr15_-_101924725 0.77 ENSMUST00000023797.6
keratin 4
chr5_-_52566264 0.76 ENSMUST00000039750.5
leucine-rich repeat LGI family, member 2
chr5_-_138171248 0.76 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr6_-_122609964 0.76 ENSMUST00000032211.4
growth differentiation factor 3
chr6_-_56362356 0.76 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
phosphodiesterase 1C
chr18_-_35662180 0.76 ENSMUST00000025209.4
ENSMUST00000096573.2
spermatogenesis associated 24
chr5_-_136170634 0.75 ENSMUST00000041048.1
ORAI calcium release-activated calcium modulator 2
chr6_+_86404257 0.73 ENSMUST00000095752.2
ENSMUST00000130967.1
cytotoxic granule-associated RNA binding protein 1
chr14_+_54632329 0.73 ENSMUST00000173083.1
predicted gene, 20726
chr16_-_18629864 0.73 ENSMUST00000096987.5
septin 5
chr5_-_137212389 0.72 ENSMUST00000179412.1
RIKEN cDNA A630081J09 gene
chr6_+_52714219 0.72 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1 (human T cell leukemia virus type I) binding protein 1
chr19_+_7268296 0.72 ENSMUST00000066646.4
REST corepressor 2
chr14_+_121035194 0.72 ENSMUST00000135010.1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr5_-_138171216 0.72 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr15_-_95528702 0.71 ENSMUST00000166170.1
NEL-like 2
chr19_-_5273080 0.71 ENSMUST00000025786.7
phosphofurin acidic cluster sorting protein 1
chr11_-_106788845 0.71 ENSMUST00000123339.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr4_-_136835843 0.70 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Eph receptor B2
chr2_+_29890063 0.70 ENSMUST00000028128.6
outer dense fiber of sperm tails 2
chr15_-_83149270 0.70 ENSMUST00000129372.1
polymerase (DNA-directed), delta interacting protein 3
chr2_-_54085542 0.70 ENSMUST00000100089.2
reprimo, TP53 dependent G2 arrest mediator candidate
chr12_-_27342696 0.69 ENSMUST00000079063.5
SRY-box containing gene 11
chr11_-_120990871 0.69 ENSMUST00000154483.1
casein kinase 1, delta
chr14_-_70524068 0.69 ENSMUST00000022692.3
surfactant associated protein C
chr5_+_5573952 0.68 ENSMUST00000101627.2
predicted gene 8773
chrX_+_71050160 0.68 ENSMUST00000082088.3
ENSMUST00000114629.3
mastermind-like domain containing 1
chr17_-_45549655 0.67 ENSMUST00000180252.1
transmembrane protein 151B
chr4_-_115133977 0.66 ENSMUST00000051400.7
cytochrome P450, family 4, subfamily x, polypeptide 1
chr13_+_44730726 0.66 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
jumonji, AT rich interactive domain 2
chr2_+_84840612 0.65 ENSMUST00000111625.1
solute carrier family 43, member 1
chr8_+_123332676 0.64 ENSMUST00000010298.6
spire homolog 2 (Drosophila)
chrX_+_140956892 0.63 ENSMUST00000112971.1
autophagy related 4A, cysteine peptidase
chr2_+_18998332 0.62 ENSMUST00000028069.1
RIKEN cDNA 4930426L09 gene
chr2_+_125152505 0.62 ENSMUST00000110494.2
ENSMUST00000028630.2
ENSMUST00000110495.2
solute carrier family 12, member 1
chr9_-_44721383 0.61 ENSMUST00000148929.1
ENSMUST00000123406.1
pleckstrin homology-like domain, family B, member 1
chr4_-_106492283 0.60 ENSMUST00000054472.3
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr6_+_86404219 0.60 ENSMUST00000095754.3
ENSMUST00000095753.2
cytotoxic granule-associated RNA binding protein 1
chr13_+_6548154 0.60 ENSMUST00000021611.8
pitrilysin metallepetidase 1
chr15_-_95528228 0.59 ENSMUST00000075275.2
NEL-like 2
chr16_-_89960815 0.59 ENSMUST00000002588.3
T cell lymphoma invasion and metastasis 1
chr16_-_91044473 0.59 ENSMUST00000118522.1
PAX3 and PAX7 binding protein 1
chr1_+_129273344 0.59 ENSMUST00000073527.6
ENSMUST00000040311.7
thrombospondin, type I, domain containing 7B
chr11_-_109473220 0.58 ENSMUST00000070872.6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr2_+_156840966 0.58 ENSMUST00000109564.1
TGFB-induced factor homeobox 2
chr11_+_102604370 0.57 ENSMUST00000057893.5
frizzled homolog 2 (Drosophila)
chr4_+_127172866 0.56 ENSMUST00000106094.2
discs, large (Drosophila) homolog-associated protein 3
chr8_-_25101985 0.55 ENSMUST00000128715.1
ENSMUST00000064883.6
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr9_-_77544870 0.55 ENSMUST00000183873.1
leucine rich repeat containing 1
chr14_-_37098211 0.55 ENSMUST00000022337.9
cadherin-related family member 1
chr4_-_16013796 0.55 ENSMUST00000149891.1
oxidative stress induced growth inhibitor family member 2
chr9_+_119063429 0.55 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
villin-like
chr14_-_54926784 0.54 ENSMUST00000022813.6
embryonal Fyn-associated substrate
chr1_-_134955847 0.54 ENSMUST00000168381.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr4_-_68954351 0.54 ENSMUST00000030036.5
bone morphogenic protein/retinoic acid inducible neural specific 1
chr6_+_83743010 0.54 ENSMUST00000006431.6
ATPase, H+ transporting, lysosomal V1 subunit B1
chr9_-_77544829 0.54 ENSMUST00000183734.1
leucine rich repeat containing 1
chr11_-_61494173 0.53 ENSMUST00000101085.2
ENSMUST00000079080.6
ENSMUST00000108714.1
mitogen-activated protein kinase 7
chr2_+_127008711 0.53 ENSMUST00000110394.1
ENSMUST00000002063.8
adaptor-related protein complex AP-4, epsilon 1
chr2_-_39190687 0.53 ENSMUST00000142872.1
ENSMUST00000038874.5
suppressor of cancer cell invasion
chr4_+_19605451 0.53 ENSMUST00000108250.2
predicted gene 12353
chr11_+_116280939 0.52 ENSMUST00000055872.2
galanin receptor 2
chr17_-_32788284 0.52 ENSMUST00000159086.2
zinc finger protein 871
chr1_-_38129618 0.52 ENSMUST00000027251.6
REV1 homolog (S. cerevisiae)
chr7_-_126799163 0.52 ENSMUST00000032934.5
aldolase A, fructose-bisphosphate
chr11_+_67798269 0.52 ENSMUST00000168612.1
ENSMUST00000040574.4
dehydrogenase/reductase (SDR family) member 7C
chr16_+_32735886 0.50 ENSMUST00000132475.1
ENSMUST00000096106.3
mucin 4
chr1_-_153186447 0.50 ENSMUST00000027753.6
laminin, gamma 2
chr11_+_98836775 0.50 ENSMUST00000107479.2
Rap guanine nucleotide exchange factor (GEF)-like 1
chr2_+_153943919 0.50 ENSMUST00000099181.1
BPI fold containing family B, member 4
chr2_-_24935148 0.49 ENSMUST00000102935.3
ENSMUST00000133934.1
ENSMUST00000028349.7
arrestin domain containing 1
chr2_-_156111954 0.49 ENSMUST00000059647.5
ENSMUST00000109604.2
ENSMUST00000138068.1
ENSMUST00000128499.1
ENSMUST00000142960.2
ENSMUST00000136296.2
RNA binding motif protein 12
copine I
chr11_-_79146407 0.49 ENSMUST00000018478.4
ENSMUST00000108264.1
kinase suppressor of ras 1
chr4_+_137277489 0.49 ENSMUST00000045747.4
wingless-related MMTV integration site 4
chr9_+_110117703 0.48 ENSMUST00000098355.3
predicted gene 10615
chr15_-_78206391 0.48 ENSMUST00000120592.1
parvalbumin
chr5_-_99978914 0.48 ENSMUST00000112939.3
ENSMUST00000171786.1
ENSMUST00000072750.6
ENSMUST00000019128.8
ENSMUST00000172361.1
heterogeneous nuclear ribonucleoprotein D
chr5_+_123076275 0.48 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
transmembrane protein 120B
chr5_+_107437908 0.47 ENSMUST00000094541.2
BTB (POZ) domain containing 8
chr16_-_22439570 0.46 ENSMUST00000170393.1
ets variant gene 5
chr8_-_126475062 0.46 ENSMUST00000170518.1
predicted gene, 17296
chr4_+_48585193 0.46 ENSMUST00000107703.1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_+_135836380 0.46 ENSMUST00000178204.1
troponin T2, cardiac
chr2_-_170497141 0.46 ENSMUST00000038824.5
cytochrome P450, family 24, subfamily a, polypeptide 1
chr2_+_121295437 0.45 ENSMUST00000110639.1
microtubule-associated protein 1 A
chr15_-_85581809 0.45 ENSMUST00000023015.7
wingless-related MMTV integration site 7B
chr19_+_46396885 0.45 ENSMUST00000039922.6
ENSMUST00000111867.2
ENSMUST00000120778.1
suppressor of fused homolog (Drosophila)
chr11_-_34833631 0.45 ENSMUST00000093191.2
spindle apparatus coiled-coil protein 1
chr7_+_30291941 0.45 ENSMUST00000144508.1
CAP-GLY domain containing linker protein 3
chr2_+_156840077 0.44 ENSMUST00000081335.6
ENSMUST00000073352.3
TGFB-induced factor homeobox 2
chr11_+_82892116 0.44 ENSMUST00000018988.5
fibronectin type III domain containing 8
chr9_+_108826320 0.43 ENSMUST00000024238.5
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr7_-_139978709 0.43 ENSMUST00000121412.1
RIKEN cDNA 6430531B16 gene
chr3_+_37348645 0.43 ENSMUST00000038885.3
fibroblast growth factor 2
chr12_+_3807076 0.42 ENSMUST00000174817.1
DNA methyltransferase 3A
chr17_-_28517509 0.42 ENSMUST00000114792.1
ENSMUST00000177939.1
FK506 binding protein 5
chr2_-_20968526 0.42 ENSMUST00000141298.2
ENSMUST00000125783.2
Rho GTPase activating protein 21
chr2_-_24763047 0.42 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr7_+_73391160 0.41 ENSMUST00000128471.1
RGM domain family, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.9 3.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.5 3.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.5 2.6 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.4 1.3 GO:0045763 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.4 1.9 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.3 1.0 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.3 1.0 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.3 1.2 GO:0060912 cardiac cell fate specification(GO:0060912)
0.3 3.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.3 1.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.3 0.8 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.3 1.0 GO:0070889 platelet alpha granule organization(GO:0070889)
0.3 1.6 GO:0032796 uropod organization(GO:0032796)
0.3 1.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 2.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 1.3 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.2 0.5 GO:0061184 positive regulation of dermatome development(GO:0061184)
0.2 1.5 GO:0007412 axon target recognition(GO:0007412)
0.2 1.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 1.5 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.6 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.2 0.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 2.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 1.8 GO:0032264 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.2 0.6 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.2 1.5 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 1.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 0.5 GO:0070375 ERK5 cascade(GO:0070375)
0.2 0.4 GO:0051794 regulation of catagen(GO:0051794)
0.2 2.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 3.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 0.7 GO:0061386 closure of optic fissure(GO:0061386)
0.2 1.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 0.5 GO:1901355 response to rapamycin(GO:1901355)
0.2 0.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.5 GO:0061642 chemoattraction of axon(GO:0061642)
0.2 1.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.6 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.1 1.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 1.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.9 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.5 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 0.1 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.6 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.8 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.1 0.6 GO:0051697 protein delipidation(GO:0051697)
0.1 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.9 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.6 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.4 GO:0061033 bronchiole development(GO:0060435) secretion by lung epithelial cell involved in lung growth(GO:0061033) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.5 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.6 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 1.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.4 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 1.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 1.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.3 GO:0003195 tricuspid valve formation(GO:0003195)
0.1 1.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.8 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.1 0.3 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 0.4 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.7 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 3.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 1.2 GO:0001553 luteinization(GO:0001553)
0.1 0.2 GO:2000793 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.3 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1 0.6 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.8 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.8 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.3 GO:0009624 response to nematode(GO:0009624)
0.0 1.0 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.0 0.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0060295 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.1 GO:0030220 platelet formation(GO:0030220)
0.0 0.6 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 1.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0061228 regulation of pronephros size(GO:0035565) hepatoblast differentiation(GO:0061017) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.0 1.0 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.3 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.3 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.3 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.5 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.5 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0048687 regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.9 GO:1903077 cortical actin cytoskeleton organization(GO:0030866) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0099525 positive regulation of synaptic vesicle priming(GO:0010808) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0032901 regulation of neurotrophin production(GO:0032899) positive regulation of neurotrophin production(GO:0032901)
0.0 0.4 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222) regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.2 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.4 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.5 GO:0007614 short-term memory(GO:0007614)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 1.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 2.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 1.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 2.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.0 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.6 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.9 GO:0051225 spindle assembly(GO:0051225)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0030312 external encapsulating structure(GO:0030312)
0.5 3.4 GO:0008091 spectrin(GO:0008091)
0.3 1.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.2 2.1 GO:0097165 nuclear stress granule(GO:0097165)
0.2 1.5 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 0.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 1.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 2.5 GO:0042555 MCM complex(GO:0042555)
0.2 0.5 GO:0005607 laminin-2 complex(GO:0005607)
0.1 1.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.1 GO:0000796 condensin complex(GO:0000796)
0.1 2.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0001940 male pronucleus(GO:0001940)
0.1 1.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.3 GO:0042599 lamellar body(GO:0042599)
0.1 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.8 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.6 GO:0060091 kinocilium(GO:0060091)
0.1 1.4 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.8 GO:0097542 ciliary tip(GO:0097542)
0.1 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.0 GO:0000346 transcription export complex(GO:0000346)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.2 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.8 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.9 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.7 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 6.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0005914 spot adherens junction(GO:0005914)
0.0 0.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 1.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0031011 Ino80 complex(GO:0031011)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.6 3.6 GO:0015265 urea channel activity(GO:0015265)
0.6 1.7 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.5 1.9 GO:0004104 cholinesterase activity(GO:0004104)
0.5 3.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 2.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.4 1.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.4 1.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.3 3.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 0.9 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.3 1.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 2.8 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.2 0.7 GO:0035500 MH2 domain binding(GO:0035500)
0.2 1.1 GO:0070051 fibrinogen binding(GO:0070051)
0.2 2.0 GO:0034711 inhibin binding(GO:0034711)
0.2 0.8 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 1.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 2.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 0.9 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.2 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.5 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 1.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.8 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 2.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.5 GO:0097001 ceramide binding(GO:0097001)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.3 GO:2001069 glycogen binding(GO:2001069)
0.1 2.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 2.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.9 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 2.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 2.5 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.7 GO:0043495 protein anchor(GO:0043495)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0052851 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0001566 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.9 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 2.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.0 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.5 PID ATR PATHWAY ATR signaling pathway
0.1 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 3.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 4.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 2.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 3.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.8 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis