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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for RstA

Z-value: 0.54

Transcription factors associated with RstA

Gene Symbol Gene ID Gene Info
rstA RstA transcriptional regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rstA0.601.2e-01Click!

Activity profile of RstA motif

Sorted Z-values of RstA motif

Promoter Log-likelihood Transcript Gene Gene Info
narGHJI 2.27 nitrate reductase A, α subunit
nitrate reductase A, γ subunit
nitrate reductase A, β subunit
molybdenum cofactor assembly chaperone subunit (δ subunit) of nitrate reductase 1
ompF 1.20 outer membrane porin F
asr 0.43 acid shock protein
csgDEFG 0.20 curli secretion channel
curli assembly component
curli transport specificity factor
CsgD DNA-binding transcriptional dual regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of RstA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0071941 anaerobic electron transport chain(GO:0019645) nitrogen cycle metabolic process(GO:0071941)
0.1 1.2 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.4 GO:0010043 response to zinc ion(GO:0010043)
0.0 0.2 GO:1900190 positive regulation of protein complex assembly(GO:0031334) regulation of multi-organism process(GO:0043900) regulation of single-species biofilm formation(GO:1900190) positive regulation of DNA-templated transcription, initiation(GO:2000144)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 1.2 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0031246 intrinsic component of periplasmic side of cell outer membrane(GO:0031246)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0008940 nitrate reductase activity(GO:0008940) metallochaperone activity(GO:0016530)
0.4 1.2 GO:0042912 bacteriocin transmembrane transporter activity(GO:0022885) colicin transmembrane transporter activity(GO:0042912)
0.0 0.2 GO:0001159 bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)