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GSE67402: E.coli regulatory changes under long-term starvation

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Results for DnaA

Z-value: 0.57

Transcription factors associated with DnaA

Gene Symbol Gene ID Gene Info
diaA DnaA initiator-associating factor for replication initiation

Activity profile of DnaA motif

Sorted Z-values of DnaA motif

Network of associatons between targets according to the STRING database.

Promoter Score Transcript Gene Gene Info
guaBA 7.81 IMP dehydrogenase
GMP synthetase
nrdAB-yfaE 7.06 ribonucleoside diphosphate reductase 1, α subunit
ribonucleoside diphosphate reductase 1, β subunit, ferritin-like
2Fe-2S cluster-containing protein involved in diferric-tyrosyl radical cofactor maintenance
polA 5.11 DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease
dnaAN-recF 2.85 chromosomal replication initiator protein DnaA; DNA-binding transcriptional dual regulator
ssDNA and dsDNA binding, ATP binding
DNA polymerase III, β subunit
rpoH 0.95 RNA polymerase, sigma 32 (sigma H) factor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037) GTP metabolic process(GO:0046039) guanosine-containing compound biosynthetic process(GO:1901070)
1.3 5.1 GO:0006284 base-excision repair(GO:0006284)
1.2 7.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.6 2.8 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731) DNA biosynthetic process(GO:0071897)
0.2 0.9 GO:0001121 transcription from bacterial-type RNA polymerase promoter(GO:0001121)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.1 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 15.0 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.0 7.8 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
1.7 5.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.2 0.9 GO:0000996 transcription factor activity, core RNA polymerase binding(GO:0000990) core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) sigma factor activity(GO:0016987)
0.1 2.8 GO:1990837 sequence-specific double-stranded DNA binding(GO:1990837)