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GSE67402: E.coli regulatory changes under long-term starvation

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Results for FlhDC

Z-value: 1.17

Transcription factors associated with FlhDC

Gene Symbol Gene ID Gene Info

Activity profile of FlhDC motif

Sorted Z-values of FlhDC motif

Network of associatons between targets according to the STRING database.

Promoter Score Transcript Gene Gene Info
flgBCDEFGHIJ 33.15 flagellar basal-body rod protein FlgC
flagellar basal-body rod protein FlgB
flagellar basal-body rod protein FlgG
flagellar basal-body rod protein FlgF
flagellar hook protein FlgE
flagellar biosynthesis, initiation of hook assembly
FlgJ
flagellar P-ring protein FlgI
flagellar L-ring protein FlgH; basal-body outer-membrane L (lipopolysaccharide layer) ring protein
flgKL 21.98 flagellar biosynthesis, hook-filament junction protein 1
flagellar biosynthesis; hook-filament junction protein
flhBAE 18.93 flagellar biosynthesis protein FlhB
flagellar biosynthesis protein FlhA
flagellar protein
flgAMN 17.91 flagellar biosynthesis; assembly of basal-body periplasmic P ring
flagellar biosynthesis protein FlgN
anti-sigma factor for FliA (σ28)
yecR 14.55 predicted protein
mdh 10.98 malate dehydrogenase
napFDAGHBC-ccmABCDEFGH 4.37 ferredoxin-type protein
ferredoxin-type protein
signal peptide-binding chaperone for NapA
periplasmic nitrate reductase, cytochrome c protein
holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmH
large subunit of periplasmic nitrate reductase, molybdoprotein
membrane anchored periplasmic heme chaperone CcmE
ABC complex for formation and release of holoCcmE - membrane subunit CcmD
holocytochrome c synthetase - thiol:disulfide oxidoreductase CcmG
holocytochrome c synthetase - CcmF subunit
ABC complex for formation and release of holoCcmE - ATP binding subunit
ABC complex for formation and release of holoCcmE - membrane subunit CcmC
ABC complex for formation and release of holoCcmE - membrane subunit CcmB
ferredoxin-type protein
subunit of periplasmic nitrate reductase, cytochrome c550 protein
mglBAC 2.96 D-galactose / D-galactoside ABC transporter - ATP binding subunit
D-galactose / D-galactoside ABC transporter - periplasmic binding protein
D-galactose / D-galactoside ABC transporter - membrane subunit
nrfABCDEFG 2.62 activator of formate-dependent nitrite reductase complex
NrfG
formate dependent nitrite reductase - NrfD subunit
formate-dependent nitrite reductase; possible assembly function
formate-dependent nitrite reductase - penta-heme cytochrome c
formate-dependent nitrite reductase, 4Fe-4S subunit
formate dependent nitrite reductase - NrfA subunit
ppdAB-ygdB-ppdC-recC 2.00 conserved protein
conserved protein
predicted protein
predicted protein
RecC

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 30.7 GO:0044781 bacterial-type flagellum assembly(GO:0044780) bacterial-type flagellum organization(GO:0044781)
3.8 22.9 GO:0071978 bacterial-type flagellum-dependent swarming motility(GO:0071978)
3.7 11.0 GO:0006108 malate metabolic process(GO:0006108)
3.0 17.9 GO:0030162 regulation of proteolysis(GO:0030162)
2.3 7.0 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
1.0 3.0 GO:0015765 methylgalactoside transport(GO:0015765)
0.7 2.0 GO:0044355 clearance of foreign intracellular DNA(GO:0044355)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 21.3 GO:0009288 bacterial-type flagellum(GO:0009288)
1.5 4.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.7 2.0 GO:0009338 exodeoxyribonuclease V complex(GO:0009338)
0.6 11.0 GO:0019898 extrinsic component of membrane(GO:0019898)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 17.9 GO:0016989 sigma factor antagonist activity(GO:0016989)
1.5 4.4 GO:0005048 signal sequence binding(GO:0005048)
1.0 3.0 GO:0015592 methylgalactoside transmembrane transporter activity(GO:0015592)
0.7 2.0 GO:0008854 exodeoxyribonuclease V activity(GO:0008854)
0.7 2.6 GO:0016662 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)