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GSE67402: E.coli regulatory changes under long-term starvation

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Results for ArgP

Z-value: 1.36

Transcription factors associated with ArgP

Gene Symbol Gene ID Gene Info
argP ArgP transcriptional activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
argP0.764.3e-06Click!

Activity profile of ArgP motif

Sorted Z-values of ArgP motif

Promoter Log-likelihood Transcript Gene Gene Info
nrdAB-yfaE 20.55 ribonucleoside diphosphate reductase 1, α subunit
ribonucleoside diphosphate reductase 1, β subunit, ferritin-like
2Fe-2S cluster-containing protein involved in diferric-tyrosyl radical cofactor maintenance
gdhA 17.30 glutamate dehydrogenase
lysC 11.14 aspartate kinase III
argP 8.91 ArgP transcriptional activator
dapD 8.90 tetrahydrodipicolinate succinylase
lysP 6.89 lysine:H+ symporter
dnaAN-recF 4.12 chromosomal replication initiator protein DnaA; DNA-binding transcriptional dual regulator
ssDNA and dsDNA binding, ATP binding
DNA polymerase III, β subunit
dapB 2.01 4-hydroxy-tetrahydrodipicolinate reductase
lysA 1.43 diaminopimelate decarboxylase

Network of associatons between targets according to the STRING database.

First level regulatory network of ArgP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.1 GO:0009090 homoserine biosynthetic process(GO:0009090) homoserine metabolic process(GO:0009092)
3.6 10.9 GO:0019877 diaminopimelate biosynthetic process(GO:0019877)
3.4 20.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
3.0 8.9 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174) negative regulation of DNA-dependent DNA replication(GO:2000104)
2.2 17.3 GO:0043650 dicarboxylic acid biosynthetic process(GO:0043650)
2.1 4.1 GO:0006275 regulation of DNA replication(GO:0006275)
1.4 6.9 GO:1902022 lysine transport(GO:0015819) L-lysine transport(GO:1902022)
0.4 1.4 GO:0046451 diaminopimelate metabolic process(GO:0046451)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 20.5 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 43.5 GO:0005829 cytosol(GO:0005829)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 20.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.7 11.1 GO:0004072 aspartate kinase activity(GO:0004072) amino acid kinase activity(GO:0019202)
2.9 17.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
1.8 8.9 GO:0016748 succinyltransferase activity(GO:0016748)
1.3 8.9 GO:0003681 bent DNA binding(GO:0003681)
0.2 2.0 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 4.1 GO:1990837 sequence-specific double-stranded DNA binding(GO:1990837)
0.1 1.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 6.9 GO:0042802 identical protein binding(GO:0042802)