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Results for HAL9

Z-value: 0.73

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Transcription factors associated with HAL9

Gene Symbol Gene ID Gene Info
HAL9
S000005449 Putative transcription factor containing a zinc finger

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HAL9YOL089C-0.644.0e-04Click!

Activity profile of HAL9 motif

Sorted Z-values of HAL9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YJR094W-A 5.82
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YHR216W 4.74
IMD2
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
YLR154W-A 4.58 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154W-B 4.46 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154C 4.39
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YIR021W 4.11
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YPL250W-A 3.98 Identified by fungal homology and RT-PCR
YKR092C 3.92
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YLL045C 3.61
RPL8B
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
YGL209W 3.61
MIG2
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
YLR154W-C 3.29
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YDL075W 3.16
RPL31A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YLR349W 3.02 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified ORF DIC1/YLR348C
YPR148C 2.90 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YLR348C 2.86
DIC1
Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix
YGR280C 2.79
PXR1
Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain
YNR013C 2.78
PHO91
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YLR301W 2.77 Protein of unknown function that interacts with Sec72p
YOR101W 2.77
RAS1
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
YNL178W 2.74
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YJL136C 2.65
RPS21B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein
YFL022C 2.63
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YJL153C 2.51
INO1
Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
YLR413W 2.33 Putative protein of unknown function; YLR413W is not an essential gene
YIL056W 2.28
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YHR141C 2.26
RPL42B
Protein component of the large (60S) ribosomal subunit, identical to Rpl42Ap and has similarity to rat L44; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus
YCL024W 2.23
KCC4
Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p
YDR037W 2.23
KRS1
Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis
YKL096W-A 2.20
CWP2
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YPL249C-A 2.13
RPL36B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Ap and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA
YDR497C 2.07
ITR1
Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p
YDR418W 1.99
RPL12B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins
YMR108W 1.99
ILV2
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control
YMR102C 1.96 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YLR185W 1.92
RPL37A
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein
YCL023C 1.91 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF KCC4
YIL133C 1.89
RPL16A
N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
YLR183C 1.74
TOS4
Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF
YNL153C 1.73
GIM3
Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
YMR009W 1.71
ADI1
Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions
YPR074C 1.69
TKL1
Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
YDL082W 1.69
RPL13A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Bp; not essential for viability; has similarity to rat L13 ribosomal protein
YOL127W 1.63
RPL25
Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif
YIL118W 1.61
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YDL083C 1.60
RPS16B
Protein component of the small (40S) ribosomal subunit; identical to Rps16Ap and has similarity to E. coli S9 and rat S16 ribosomal proteins
YML024W 1.60
RPS17A
Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Bp and has similarity to rat S17 ribosomal protein
YGL201C 1.58
MCM6
Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
YFL015W-A 1.57 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YPL062W 1.54 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation
YGR138C 1.54
TPO2
Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily
YKL218C 1.54
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YPL137C 1.53
GIP3
Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments
YGR148C 1.50
RPL24B
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YIL121W 1.48
QDR2
Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake
YNL090W 1.48
RHO2
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involved in the establishment of cell polarity and in microtubule assembly
YFL015C 1.46 Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene
YMR099C 1.46 Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase), likely involved in carbohydrate metabolism; GFP-fusion protein localizes to both the nucleus and cytoplasm and is induced in response to the DNA-damaging agent MMS
YER146W 1.46
LSM5
Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA
YNL069C 1.42
RPL16B
N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
YHR136C 1.41
SPL2
Protein with similarity to cyclin-dependent kinase inhibitors, overproduction suppresses a plc1 null mutation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YJL190C 1.40
RPS22A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins
YKL120W 1.38
OAC1
Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and thiosulfate; member of the mitochondrial carrier family
YKR093W 1.36
PTR2
Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p
YLR048W 1.32
RPS0B
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
YOL101C 1.32
IZH4
Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism
YGR097W 1.32
ASK10
Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes
YMR121C 1.31
RPL15B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
YNR016C 1.31
ACC1
Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
YGR242W 1.30 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C
YKR074W 1.30
AIM29
Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
YOR340C 1.25
RPA43
RNA polymerase I subunit A43
YFR055W 1.25
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YOR163W 1.23
DDP1
Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases
YMR208W 1.22
ERG12
Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
YGR140W 1.20
CBF2
Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
YDR144C 1.19
MKC7
GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p
YJL212C 1.17
OPT1
Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family
YHR137W 1.17
ARO9
Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism
YGR241C 1.17
YAP1802
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family
YPR063C 1.16 ER-localized protein of unknown function
YGR118W 1.15
RPS23A
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal
YOR234C 1.13
RPL33B
Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable
YHR020W 1.12 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to proline-tRNA ligase; YHR020W is an essential gene
YGR034W 1.11
RPL26B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
YDR344C 1.11 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR128C 1.08
UTP8
Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
YHR094C 1.07
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YFR056C 1.07 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YMR100W 1.06
MUB1
Protein of unknown function, deletion causes multi-budding phenotype; has similarity to Aspergillus nidulans samB gene
YLR333C 1.05
RPS25B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein
YGR139W 0.99 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGL035C 0.99
MIG1
Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase
YDR215C 0.99 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein
YDL241W 0.97 Putative protein of unknown function; YDL241W is not an essential gene
YNL089C 0.97 Dubious open reading frame unlikely to encode a functional protein; almost completely overlaps YNL090W/RHO2 which encodes a small GTPase of the Rho/Rac subfamily of Ras-like proteins
YMR267W 0.96
PPA2
Mitochondrial inorganic pyrophosphatase, required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate
YGR017W 0.96 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm
YCR099C 0.96 Putative protein of unknown function
YKR094C 0.96
RPL40B
Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes
YGR052W 0.94
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YPL170W 0.94
DAP1
Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis
YPL136W 0.94 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene GIP3/YPL137C
YIL039W 0.93
TED1
Conserved phosphoesterase domain-containing protein that acts together with Emp24p/Erv25p in cargo exit from the ER; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
YLL028W 0.92
TPO1
Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane
YLR025W 0.91
SNF7
One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes
YLR448W 0.89
RPL6B
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA
YJR094C 0.89
IME1
Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p
YLR262C-A 0.88
TMA7
Protein of unknown that associates with ribosomes; null mutant exhibits translation defects, altered polyribosome profiles, and resistance to the translation inhibitor anisomcyin
YJL222W 0.87
VTH2
Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in vacuolar protein sorting
YML063W 0.87
RPS1B
Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein
YBR106W 0.86
PHO88
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
YGR055W 0.85
MUP1
High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake
YBR118W 0.85
TEF2
Translational elongation factor EF-1 alpha; also encoded by TEF1; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes
YDL023C 0.85 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YKL106W 0.84
AAT1
Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis
YER036C 0.83
ARB1
ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome biogenesis, has similarity to Gcn20p; shuttles from nucleus to cytoplasm, physically interacts with Tif6p, Lsg1p
YKL065C 0.81
YET1
Endoplasmic reticulum transmembrane protein; may interact with ribosomes, based on co-purification experiments; homolog of human BAP31 protein
YKL068W-A 0.81 Putative protein of unknown function; identified by homology to Ashbya gossypii
YGR050C 0.80 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YBR158W 0.80
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YHR019C 0.79
DED81
Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA
YML088W 0.79
UFO1
F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation
YJR123W 0.77
RPS5
Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins
YLR344W 0.76
RPL26A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
YER001W 0.76
MNN1
Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family
YFR036W-A 0.76 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene RSC8
YLL043W 0.75
FPS1
Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glycerol and in uptake of acetic acid and the trivalent metalloids arsenite and antimonite; phosphorylated by Hog1p MAPK under acetate stress
YFL016C 0.75
MDJ1
Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones
YDR072C 0.74
IPT1
Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media
YDL022W 0.73
GPD1
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
YHR007C 0.72
ERG11
Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family
YKL110C 0.72
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YIR013C 0.72
GAT4
Protein containing GATA family zinc finger motifs
YOR119C 0.71
RIO1
Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA
YPL004C 0.69
LSP1
Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways
YGL034C 0.67 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YCR018C 0.66
SRD1
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
YDL137W 0.66
ARF2
ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf1p
YMR122W-A 0.66 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and endoplasmic reticulum
YML126C 0.65
ERG13
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis
YJR047C 0.65
ANB1
Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions
YPL131W 0.64
RPL5
Protein component of the large (60S) ribosomal subunit with similarity to E. coli L18 and rat L5 ribosomal proteins; binds 5S rRNA and is required for 60S subunit assembly
YKR038C 0.64
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YKL063C 0.64 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YNL189W 0.63
SRP1
Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation
YNL304W 0.63
YPT11
Rab-type small GTPase that interacts with the C-terminal tail domain of Myo2p to mediate distribution of mitochondria to daughter cells
YLL027W 0.63
ISA1
Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources
YOR276W 0.63
CAF20
Phosphoprotein of the mRNA cap-binding complex involved in translational control, repressor of cap-dependent translation initiation, competes with eIF4G for binding to eIF4E
YJL223C 0.62
PAU1
Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
YPL003W 0.62
ULA1
Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation
YJL173C 0.62
RFA3
Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
YJL115W 0.61
ASF1
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
YDR451C 0.61
YHP1
One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval
YBL032W 0.61
HEK2
RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length
YEL020C-B 0.61 Dubious open reading frame unlikely to encode a protein; partially overlaps verified gene YEL020W-A; identified by fungal homology and RT-PCR
YPR074W-A 0.60 Hypothetical protein identified by homology
YIR019C 0.60
MUC1
GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
YKL209C 0.60
STE6
Plasma membrane ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells
YNL302C 0.59
RPS19B
Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Ap
YJL222W-A 0.59 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YDL081C 0.59
RPP1A
Ribosomal stalk protein P1 alpha, involved in the interaction between translational elongation factors and the ribosome; accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component
YLR110C 0.58
CCW12
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
YEL001C 0.57
IRC22
Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci
YGR051C 0.57 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene
YEL056W 0.55
HAT2
Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
YNR028W 0.55
CPR8
Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; similarity to Cpr4p suggests a potential role in the secretory pathway
YKL001C 0.55
MET14
Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism
YIL069C 0.55
RPS24B
Protein component of the small (40S) ribosomal subunit; identical to Rps24Ap and has similarity to rat S24 ribosomal protein
YHR169W 0.54
DBP8
Putative ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 40S ribosomal subunit
YHR142W 0.54
CHS7
Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER
YNL065W 0.54
AQR1
Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids
YIL051C 0.54
MMF1
Mitochondrial protein involved in maintenance of the mitochondrial genome
YDR073W 0.54
SNF11
Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p
YDR156W 0.54
RPA14
RNA polymerase I subunit A14
YBR048W 0.54
RPS11B
Protein component of the small (40S) ribosomal subunit; identical to Rps11Ap and has similarity to E. coli S17 and rat S11 ribosomal proteins
YDL076C 0.52
RXT3
Subunit of the RPD3L complex; involved in histone deacetylation
YIR020C 0.51 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOL125W 0.51
TRM13
2'-O-methyltransferase responsible for modification of tRNA at position 4; exhibits no obvious similarity to other known methyltransferases
YGR004W 0.50
PEX31
Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p
YPL178W 0.49
CBC2
Small subunit of the heterodimeric cap binding complex that also contains Sto1p, component of the spliceosomal commitment complex; interacts with Npl3p, possibly to package mRNA for export from the nucleus; contains an RNA-binding motif
YNL251C 0.49
NRD1
RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), required for transcription termination and 3' end maturation of nonpolyadenylated RNAs
YAL038W 0.49
CDC19
Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
YBL063W 0.48
KIP1
Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p
YPL112C 0.48
PEX25
Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p
YPL263C 0.48
KEL3
Cytoplasmic protein of unknown function
YGL031C 0.47
RPL24A
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YDR074W 0.47
TPS2
Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
YML026C 0.46
RPS18B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins
YEL062W 0.46
NPR2
Protein with a possible role in regulating expression of nitrogen permeases; transcription is induced in response to proline and urea; contains two PEST sequences; null mutant is resistant to cisplatin and doxorubicin
YJL216C 0.45 Protein of unknown function, similar to alpha-D-glucosidases; transcriptionally activated by both Pdr8p and Yrm1p, along with transporters and other genes involved in the pleiotropic drug resistance (PDR) phenomenon
YER045C 0.45
ACA1
Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources
YER046W 0.45
SPO73
Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis
YIR020W-A 0.45 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YJL011C 0.44
RPC17
RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex
YOL014W 0.44 Putative protein of unknown function
YFR031C-A 0.44
RPL2A
Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins
YNL118C 0.44
DCP2
Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family
YBL006C 0.43
LDB7
Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions
YPR025C 0.43
CCL1
Cyclin associated with protein kinase Kin28p, which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters
YJL029C 0.42
VPS53
Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; required for vacuolar protein sorting

Network of associatons between targets according to the STRING database.

First level regulatory network of HAL9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0006183 GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039)
1.2 1.2 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
1.2 4.8 GO:1900434 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
1.1 4.3 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
0.9 2.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.9 2.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.7 2.8 GO:0000296 spermine transport(GO:0000296)
0.7 2.8 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.7 4.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.6 6.8 GO:0006817 phosphate ion transport(GO:0006817)
0.6 2.4 GO:0014070 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.6 2.3 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.5 4.1 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.5 2.0 GO:0033866 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.5 1.4 GO:0008272 sulfate transport(GO:0008272) C4-dicarboxylate transport(GO:0015740)
0.4 2.6 GO:0006021 inositol biosynthetic process(GO:0006021)
0.4 1.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.4 1.2 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.4 2.7 GO:0015791 polyol transport(GO:0015791)
0.4 1.5 GO:0090337 regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338)
0.3 2.0 GO:0009099 valine biosynthetic process(GO:0009099)
0.3 49.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.3 2.3 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 0.9 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.3 1.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.3 1.2 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.3 0.9 GO:0071454 response to anoxia(GO:0034059) cellular response to anoxia(GO:0071454)
0.3 1.8 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.3 1.5 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 2.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 2.6 GO:0006857 oligopeptide transport(GO:0006857)
0.2 1.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.2 0.6 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.2 1.1 GO:0050810 regulation of steroid metabolic process(GO:0019218) regulation of ergosterol biosynthetic process(GO:0032443) regulation of steroid biosynthetic process(GO:0050810)
0.2 0.8 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 0.9 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.2 0.6 GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.2 1.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.2 GO:0032233 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.2 0.5 GO:1900062 regulation of cell aging(GO:0090342) regulation of replicative cell aging(GO:1900062)
0.2 0.5 GO:0030541 plasmid partitioning(GO:0030541)
0.2 0.6 GO:0048313 Golgi inheritance(GO:0048313)
0.2 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.2 0.5 GO:0032006 regulation of TOR signaling(GO:0032006)
0.2 0.3 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.6 GO:0051597 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.1 0.6 GO:0015833 peptide transport(GO:0015833)
0.1 1.3 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.1 0.6 GO:0007157 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.1 0.3 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239)
0.1 2.5 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.5 GO:0009097 isoleucine biosynthetic process(GO:0009097)
0.1 0.8 GO:0045116 protein neddylation(GO:0045116)
0.1 1.1 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.1 0.5 GO:0071041 antisense RNA transcript catabolic process(GO:0071041)
0.1 0.6 GO:0006336 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-dependent nucleosome organization(GO:0034723) positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.3 GO:0006344 maintenance of chromatin silencing(GO:0006344) maintenance of chromatin silencing at telomere(GO:0035392)
0.1 1.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.6 GO:0006768 biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102)
0.1 2.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 2.0 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 0.4 GO:0015809 arginine transport(GO:0015809)
0.1 2.2 GO:0006885 regulation of pH(GO:0006885)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.8 GO:0000084 mitotic S phase(GO:0000084) S phase(GO:0051320)
0.1 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.2 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.7 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 0.1 GO:0043068 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.1 0.6 GO:0009312 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.1 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.6 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 0.3 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.6 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 0.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.3 GO:0042710 biofilm formation(GO:0042710)
0.1 1.4 GO:0044108 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.1 1.5 GO:0009267 cellular response to starvation(GO:0009267)
0.1 0.8 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208)
0.1 0.3 GO:0070941 eisosome assembly(GO:0070941)
0.1 0.5 GO:0051329 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.1 0.8 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.4 GO:0031506 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506)
0.1 0.4 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.1 0.6 GO:0006415 translational termination(GO:0006415)
0.1 0.4 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
0.0 0.2 GO:0015883 FAD transport(GO:0015883)
0.0 0.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0006276 plasmid maintenance(GO:0006276)
0.0 0.5 GO:0034221 fungal-type cell wall chitin biosynthetic process(GO:0034221) fungal-type cell wall polysaccharide biosynthetic process(GO:0051278) fungal-type cell wall polysaccharide metabolic process(GO:0071966)
0.0 0.3 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0072503 cellular divalent inorganic cation homeostasis(GO:0072503) divalent inorganic cation homeostasis(GO:0072507)
0.0 0.3 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.6 GO:0017148 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 1.0 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 1.0 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.8 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 3.6 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0034517 ribophagy(GO:0034517)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.5 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:0007009 plasma membrane organization(GO:0007009)
0.0 0.2 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.1 GO:0006827 high-affinity iron ion transmembrane transport(GO:0006827)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0000743 nuclear migration involved in conjugation with cellular fusion(GO:0000743)
0.0 0.2 GO:0007323 peptide pheromone maturation(GO:0007323)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.6 GO:0007017 microtubule-based process(GO:0007017)
0.0 0.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0000741 karyogamy(GO:0000741) karyogamy involved in conjugation with cellular fusion(GO:0000742)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0019358 nicotinate nucleotide biosynthetic process(GO:0019357) nicotinate nucleotide salvage(GO:0019358) pyridine nucleotide salvage(GO:0019365) nicotinate nucleotide metabolic process(GO:0046497)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:2000284 positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.6 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.5 GO:0046939 nucleotide phosphorylation(GO:0046939)
0.0 0.0 GO:0031070 intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965)
0.0 0.2 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0007535 donor selection(GO:0007535)
0.0 0.5 GO:0042244 ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940)
0.0 0.2 GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion(GO:0000754) adaptation of signaling pathway(GO:0023058)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0044091 ascospore-type prospore membrane assembly(GO:0032120) membrane biogenesis(GO:0044091) membrane assembly(GO:0071709)
0.0 0.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.0 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.0 GO:0009452 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0 1.7 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.1 GO:0000917 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529)
0.0 0.2 GO:1901264 carbohydrate derivative transport(GO:1901264)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 38.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 1.2 GO:0031518 CBF3 complex(GO:0031518)
0.3 18.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 1.6 GO:0042555 MCM complex(GO:0042555)
0.2 1.7 GO:0016272 prefoldin complex(GO:0016272)
0.2 1.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.2 1.1 GO:0034518 RNA cap binding complex(GO:0034518)
0.2 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 0.5 GO:0035649 Nrd1 complex(GO:0035649)
0.2 2.4 GO:0005940 septin ring(GO:0005940)
0.2 1.3 GO:0005688 U6 snRNP(GO:0005688)
0.2 1.2 GO:0033101 cellular bud membrane(GO:0033101)
0.2 1.1 GO:0034455 t-UTP complex(GO:0034455)
0.2 2.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 0.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.6 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.1 0.4 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 3.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 2.4 GO:0070210 Rpd3L-Expanded complex(GO:0070210)
0.1 0.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0030428 cell septum(GO:0030428)
0.1 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0097042 extrinsic component of fungal-type vacuolar membrane(GO:0097042)
0.1 0.4 GO:0000938 GARP complex(GO:0000938)
0.1 0.5 GO:0030689 Noc complex(GO:0030689)
0.1 0.4 GO:0070860 RNA polymerase I core factor complex(GO:0070860)
0.1 0.5 GO:0005871 kinesin complex(GO:0005871)
0.1 1.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.2 GO:0030118 clathrin coat(GO:0030118)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 8.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0034967 Set3 complex(GO:0034967)
0.0 0.3 GO:0090544 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)
0.0 0.1 GO:0044697 HICS complex(GO:0044697)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0044462 cell wall part(GO:0044426) external encapsulating structure part(GO:0044462)
0.0 0.4 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0034099 luminal surveillance complex(GO:0034099)
0.0 0.6 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 2.7 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0043332 mating projection tip(GO:0043332)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.8 GO:0000131 incipient cellular bud site(GO:0000131)
0.0 0.1 GO:0071819 DUBm complex(GO:0071819)
0.0 0.1 GO:0032126 eisosome(GO:0032126)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 1.5 GO:0005933 cellular bud(GO:0005933)
0.0 0.1 GO:0044453 nuclear outer membrane(GO:0005640) nuclear membrane part(GO:0044453)
0.0 0.8 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0098797 plasma membrane protein complex(GO:0098797)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
1.1 4.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.0 3.0 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.9 2.8 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.9 2.8 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.9 2.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.8 2.5 GO:0016872 intramolecular lyase activity(GO:0016872)
0.7 2.2 GO:0072341 modified amino acid binding(GO:0072341)
0.7 0.7 GO:0032451 demethylase activity(GO:0032451)
0.7 2.8 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.5 4.2 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.5 2.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.4 1.8 GO:1904680 peptide transmembrane transporter activity(GO:1904680)
0.4 2.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.4 1.6 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
0.4 1.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.4 1.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.4 1.5 GO:0016854 ammonia-lyase activity(GO:0016841) racemase and epimerase activity(GO:0016854)
0.4 1.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 0.9 GO:0019003 GDP binding(GO:0019003)
0.3 2.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.3 4.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 1.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.3 53.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 0.2 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825)
0.2 2.2 GO:0051213 dioxygenase activity(GO:0051213)
0.2 1.7 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.2 3.8 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.2 1.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 2.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.2 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.2 2.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 0.8 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.3 GO:0004805 trehalose-phosphatase activity(GO:0004805)
0.1 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.3 GO:0000049 tRNA binding(GO:0000049)
0.1 0.3 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.3 GO:0004000 adenosine deaminase activity(GO:0004000) tRNA-specific adenosine deaminase activity(GO:0008251)
0.1 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 2.9 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 6.3 GO:0003924 GTPase activity(GO:0003924)
0.1 0.4 GO:0042973 glucan endo-1,3-beta-D-glucosidase activity(GO:0042973)
0.1 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.6 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 0.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864) phosphatase inhibitor activity(GO:0019212)
0.1 0.4 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.4 GO:0005354 galactose transmembrane transporter activity(GO:0005354)
0.1 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.1 2.0 GO:0015631 tubulin binding(GO:0015631)
0.1 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.7 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.1 0.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.6 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0005034 osmosensor activity(GO:0005034)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.8 GO:0005048 signal sequence binding(GO:0005048)
0.0 1.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.3 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0004338 glucan exo-1,3-beta-glucosidase activity(GO:0004338)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 2.2 GO:0008289 lipid binding(GO:0008289)
0.0 0.1 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0051287 NAD binding(GO:0051287)
0.0 0.1 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.0 0.1 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0072509 divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.0 0.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.6 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 PID SHP2 PATHWAY SHP2 signaling
0.1 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.3 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.2 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.1 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
0.6 1.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 3.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 0.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.3 4.9 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 1.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 0.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.2 1.3 REACTOME METABOLISM OF MRNA Genes involved in Metabolism of mRNA
0.1 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.1 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events