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Results for SKO1

Z-value: 0.75

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Transcription factors associated with SKO1

Gene Symbol Gene ID Gene Info
SKO1
S000005111 Basic leucine zipper transcription factor of the ATF/CREB family

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SKO1YNL167C-0.086.9e-01Click!

Activity profile of SKO1 motif

Sorted Z-values of SKO1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YFR056C 6.76 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YFR055W 6.52
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YNL178W 4.40
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YFL022C 2.69
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YDR044W 2.58
HEM13
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
YPR119W 2.57
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YHR094C 2.55
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YML127W 2.52
RSC9
Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway
YDL023C 2.45 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YJR145C 2.23
RPS4A
Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
YHR181W 2.16
SVP26
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
YGR148C 2.13
RPL24B
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YMR037C 2.05
MSN2
Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
YDL022W 2.02
GPD1
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
YOR063W 2.01
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YBR181C 1.95
RPS6B
Protein component of the small (40S) ribosomal subunit; identical to Rps6Ap and has similarity to rat S6 ribosomal protein
YKL182W 1.93
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YDL022C-A 1.90 Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene DIA3; identified by fungal homology and RT-PCR
YHR180W-A 1.87 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious ORF YHR180C-B and long terminal repeat YHRCsigma3
YKL110C 1.86
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YBL063W 1.83
KIP1
Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p
YOR226C 1.79
ISU2
Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable
YER102W 1.78
RPS8B
Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to rat S8 ribosomal protein
YDR023W 1.78
SES1
Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p
YOL127W 1.77
RPL25
Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif
YNR054C 1.73
ESF2
Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome
YDR399W 1.72
HPT1
Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
YDR417C 1.70 Hypothetical protein
YGR242W 1.68 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C
YLR048W 1.62
RPS0B
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
YLR448W 1.58
RPL6B
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA
YFR031C-A 1.54
RPL2A
Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins
YFR054C 1.51 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR241C 1.51
YAP1802
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family
YDR098C 1.44
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YEL053W-A 1.44 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YEL054C
YCR099C 1.43 Putative protein of unknown function
YBL003C 1.43
HTA2
One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
YNL043C 1.42 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YIP3/YNL044W
YER137C 1.41 Putative protein of unknown function
YDR279W 1.41
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YPL062W 1.38 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation
YGL031C 1.37
RPL24A
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YGL135W 1.36
RPL1B
N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Ap and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal
YDR509W 1.35 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDL047W 1.35
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YGL097W 1.34
SRM1
Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p
YJL115W 1.31
ASF1
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
YBL031W 1.30
SHE1
Cytoskeletal protein of unknown function; overexpression causes growth arrest
YCR087W 1.28 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized gene YCR087C-A; YCR087W is not an essential gene
YGR086C 1.24
PIL1
Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria
YLR257W 1.23 Putative protein of unknown function
YMR177W 1.22
MMT1
Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt2p
YLR108C 1.22 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene
YGR052W 1.21
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YLR355C 1.19
ILV5
Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids
YGL179C 1.16
TOS3
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YDR508C 1.16
GNP1
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
YKR026C 1.13
GCN3
Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression
YOR028C 1.12
CIN5
Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus
YPR063C 1.12 ER-localized protein of unknown function
YNR013C 1.12
PHO91
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YHR196W 1.10
UTP9
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
YDL048C 1.09
STP4
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p
YPR010C 1.09
RPA135
RNA polymerase I subunit A135
YKR079C 1.08
TRZ1
tRNase Z, involved in RNA processing, has two putative nucleotide triphosphate-binding motifs (P-loop) and a conserved histidine motif, homolog of the human candidate prostate cancer susceptibility gene ELAC2
YER073W 1.05
ALD5
Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed
YBL002W 1.05
HTB2
One of two nearly identical (see HTB1) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
YGL030W 1.04
RPL30
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript
YOR101W 1.04
RAS1
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
YPL075W 1.02
GCR1
Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
YDR041W 1.02
RSM10
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins
YER043C 1.00
SAH1
S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor
YOL031C 0.99
SIL1
Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chaperone Kar2p, required for protein translocation into the ER; homolog of Yarrowia lipolytica SLS1; GrpE-like protein
YOR092W 0.98
ECM3
Non-essential protein of unknown function; involved in signal transduction and the genotoxic response; induced rapidly in response to treatment with 8-methoxypsoralen and UVA irradiation
YJL107C 0.97 Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
YLR276C 0.96
DBP9
ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit
YBR195C 0.94
MSI1
Subunit of chromatin assembly factor I (CAF-1), negative regulator of the RAS/cAMP pathway via sequestration of Npr1p kinase; localizes to the nucleus and cytoplasm; homologous to human retinoblastoma binding proteins RbAp48 and RbAp46
YPL137C 0.94
GIP3
Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments
YDL192W 0.92
ARF1
ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p
YGR159C 0.91
NSR1
Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis
YMR083W 0.91
ADH3
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
YIR033W 0.90
MGA2
ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting
YLR154C 0.90
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YGR249W 0.89
MGA1
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
YMR049C 0.88
ERB1
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
YJL106W 0.88
IME2
Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p
YLR314C 0.88
CDC3
Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
YER048W-A 0.88
ISD11
Protein required for mitochondrial iron-sulfur cluster biosynthesis
YLR109W 0.87
AHP1
Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
YDR240C 0.85
SNU56
Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; interacts with mRNA in commitment complex
YGR035C 0.85 Putative protein of unknown function, potential Cdc28p substrate; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
YDR510W 0.84
SMT3
Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics
YGL258W 0.84
VEL1
Protein of unknown function; highly induced in zinc-depleted conditions and has increased expression in NAP1 deletion mutants
YML088W 0.84
UFO1
F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation
YOL139C 0.84
CDC33
Cytoplasmic mRNA cap binding protein; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with the translation initiation factor eIF4G (Tif4631p or Tif4632p)
YHL003C 0.82
LAG1
Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p
YGL009C 0.82
LEU1
Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway
YDR074W 0.82
TPS2
Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
YGR040W 0.82
KSS1
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
YGR051C 0.81 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene
YKR090W 0.81
PXL1
LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin
YPL037C 0.80
EGD1
Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b
YPR163C 0.80
TIF3
Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA
YOR025W 0.80
HST3
Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
YDR278C 0.80 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YER074W 0.80
RPS24A
Protein component of the small (40S) ribosomal subunit; identical to Rps24Bp and has similarity to rat S24 ribosomal protein
YIL009W 0.79
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YGR108W 0.79
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YDR361C 0.79
BCP1
Essential protein involved in nuclear export of Mss4p, which is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport
YGR050C 0.79 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YKL128C 0.77
PMU1
Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant
YCR098C 0.76
GIT1
Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability
YCR034W 0.76
FEN1
Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway
YJL158C 0.76
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YOR029W 0.75 Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data
YBR158W 0.75
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YLL011W 0.74
SOF1
Essential protein required for biogenesis of 40S (small) ribosomal subunit; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p
YIL076W 0.73
SEC28
Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth
YKR057W 0.73
RPS21A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein
YKR092C 0.72
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YNL169C 0.72
PSD1
Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts phosphatidylserine to phosphatidylethanolamine
YPL043W 0.71
NOP4
Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs)
YNL113W 0.71
RPC19
RNA polymerase subunit, common to RNA polymerases I and III
YER048C 0.71
CAJ1
Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly
YDR190C 0.71
RVB1
Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family
YKR041W 0.71 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YDL055C 0.70
PSA1
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
YDR400W 0.70
URH1
Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways
YDL084W 0.69
SUB2
Component of the TREX complex required for nuclear mRNA export; member of the DEAD-box RNA helicase superfamily and is involved in early and late steps of spliceosome assembly; homolog of the human splicing factor hUAP56
YJL153C 0.69
INO1
Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
YJL200C 0.69
ACO2
Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
YLR367W 0.69
RPS22B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins
YKL219W 0.69
COS9
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YGL244W 0.68
RTF1
Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance
YBR238C 0.67 Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span
YKL209C 0.67
STE6
Plasma membrane ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells
YGR164W 0.67 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDR040C 0.67
ENA1
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
YIL009C-A 0.66
EST3
Component of the telomerase holoenzyme, involved in telomere replication
YOR078W 0.66
BUD21
Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated as bud-site selection mutant that displays a random budding pattern
YEL029C 0.66
BUD16
Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection
YPR041W 0.66
TIF5
Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP; C-terminal domain is the core of ribosomal preinitiation complex formation
YIL056W 0.65
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YFL017C 0.65
GNA1
Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA
YMR102C 0.65 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YBL087C 0.65
RPL23A
Protein component of the large (60S) ribosomal subunit, identical to Rpl23Bp and has similarity to E. coli L14 and rat L23 ribosomal proteins
YHL028W 0.64
WSC4
ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3
YBR249C 0.64
ARO4
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan
YDR099W 0.64
BMH2
14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
YDR382W 0.64
RPP2B
Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
YER177W 0.64
BMH1
14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
YER046W 0.63
SPO73
Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis
YGL036W 0.63 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YGL036W is not an essential gene
YER003C 0.62
PMI40
Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation
YGR155W 0.62
CYS4
Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis
YDR531W 0.62 Pantothenate kinase (ATP:D-pantothenate 4'-phosphotransferase, EC 2.7.1.33); catalyzes the first committed step in the universal biosynthetic pathway leading to coenzyme A1
YGL050W 0.62
TYW3
tRNA methyltransferase required for synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions
YGR277C 0.62 Putative pantetheine-phosphate adenylyltransferase (PPAT) that catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate; conserved in bacteria, humans, and plants; essential for viability
YIR021W 0.62
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YNL038W 0.61
GPI15
Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-H protein
YDR033W 0.61
MRH1
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
YOR030W 0.61
DFG16
Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p
YDR261C 0.60
EXG2
Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor
YIL118W 0.60
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YLR300W 0.60
EXG1
Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes
YER134C 0.60 Putative protein of unknown function; non-essential gene
YOR096W 0.60
RPS7A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
YEL068C 0.60 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGL115W 0.60
SNF4
Activating gamma subunit of the AMP-activated Snf1p kinase complex (contains Snf1p and a Sip1p/Sip2p/Gal83p family member); activates glucose-repressed genes, represses glucose-induced genes; role in sporulation, and peroxisome biogenesis
YCR018C 0.59
SRD1
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
YMR290W-A 0.59 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YGL037C 0.58
PNC1
Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span
YHR162W 0.58 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion
YER135C 0.58 Dubious open reading frame unlikely to encode a protein; YER135C is not an essential gene
YKR038C 0.58
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YHR043C 0.58
DOG2
2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed
YGL102C 0.58 Dubious open reading frame unlikely to encode a functional protein; overlaps 3' end of essential RPL28 gene encoding a large subunit ribosomal protein
YER188W 0.57 Hypothetical protein
YGL262W 0.57 Putative protein of unknown function; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein; YGL262W is not an essential gene
YER136W 0.57
GDI1
GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins
YGR245C 0.57
SDA1
Highly conserved nuclear protein required for actin cytoskeleton organization and passage through Start, plays a critical role in G1 events, binds Nap1p, also involved in 60S ribosome biogenesis
YOR107W 0.56
RGS2
Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p
YBR032W 0.56 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YGR287C 0.56 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to alpha-D-glucosidase (maltase); authentic, non-tagged protein detected in purified mitochondria in high-throughput studies
YLR083C 0.56
EMP70
Protein with a role in cellular adhesion and filamentous growth; similar to Tmn2p and Tmn3p; member of Transmembrane Nine family of proteins with 9 transmembrane segments; 24kDa cleavage product found in endosome-enriched membrane fractions
YOR357C 0.56
SNX3
Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p
YOR232W 0.56
MGE1
Protein of the mitochondrial matrix involved in protein import into mitochondria; acts as a cochaperone and a nucleotide release factor for Ssc1p; homolog of E. coli GrpE
YBR138C 0.56 Cytoplasmic protein of unknown function, potentially phosphorylated by Cdc28p; YBR138C is not an essential gene
YOL092W 0.55 Putative protein of unknown function; predicted to contain six transmembrane domains and is 58% similar to the uncharacterized ORF YBR147W; deletion mutant has no detectable phenotype
YAL012W 0.55
CYS3
Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine
YGR027C 0.55
RPS25A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Bp and has similarity to rat S25 ribosomal protein
YJL173C 0.55
RFA3
Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
YLR301W 0.55 Protein of unknown function that interacts with Sec72p
YKL153W 0.54 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLK153W and the overlapping essential gene GPM1 is reduced in the gcr1 null mutant
YPR170W-B 0.54 Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C
YNL301C 0.54
RPL18B
Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein
YOR047C 0.54
STD1
Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
YER045C 0.54
ACA1
Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources
YHR152W 0.54
SPO12
Nucleolar protein of unknown function, positive regulator of mitotic exit; involved in regulating release of Cdc14p from the nucleolus in early anaphase, may play similar role in meiosis

Network of associatons between targets according to the STRING database.

First level regulatory network of SKO1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.9 2.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.8 3.1 GO:0070417 response to cold(GO:0009409) cellular response to cold(GO:0070417)
0.6 1.8 GO:0030541 plasmid partitioning(GO:0030541)
0.6 2.3 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
0.6 1.1 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.5 2.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.5 2.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 3.1 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
0.4 3.1 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.4 1.3 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.4 1.3 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.4 1.2 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.4 6.6 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.3 1.0 GO:0048024 regulation of RNA splicing(GO:0043484) regulation of mRNA splicing, via spliceosome(GO:0048024)
0.3 1.0 GO:0072363 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.3 2.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 1.3 GO:0019358 nicotinate nucleotide biosynthetic process(GO:0019357) nicotinate nucleotide salvage(GO:0019358) pyridine nucleotide salvage(GO:0019365) nicotinate nucleotide metabolic process(GO:0046497)
0.3 1.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 2.1 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.3 1.2 GO:0019346 transsulfuration(GO:0019346)
0.3 0.6 GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187) adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.3 1.1 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.3 0.8 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.3 3.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.7 GO:0046495 nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637)
0.2 1.5 GO:0009099 valine biosynthetic process(GO:0009099)
0.2 1.9 GO:0006814 sodium ion transport(GO:0006814)
0.2 0.7 GO:0035955 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.2 0.9 GO:0009423 chorismate biosynthetic process(GO:0009423)
0.2 0.9 GO:0032233 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.2 28.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 0.9 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.2 1.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.2 0.6 GO:0009094 L-phenylalanine biosynthetic process(GO:0009094) erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process(GO:1902223)
0.2 0.8 GO:0030497 fatty acid elongation(GO:0030497)
0.2 1.0 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.2 2.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.2 0.9 GO:0009302 snoRNA transcription(GO:0009302)
0.2 0.7 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.2 0.9 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 2.3 GO:0030011 maintenance of cell polarity(GO:0030011)
0.2 1.0 GO:0070941 eisosome assembly(GO:0070941)
0.2 1.7 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.2 0.5 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.2 2.6 GO:0006334 nucleosome assembly(GO:0006334)
0.2 0.8 GO:0051597 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.2 0.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 0.3 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.2 0.7 GO:0000296 spermine transport(GO:0000296)
0.2 0.7 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.2 1.0 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.2 4.9 GO:0009303 rRNA transcription(GO:0009303)
0.2 0.7 GO:0045014 negative regulation of transcription from RNA polymerase II promoter by glucose(GO:0000433) filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) negative regulation of transcription by glucose(GO:0045014) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.2 0.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.2 0.8 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.2 0.5 GO:0019413 acetate biosynthetic process(GO:0019413)
0.2 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 0.9 GO:0051094 positive regulation of developmental process(GO:0051094)
0.2 0.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 0.4 GO:1901976 regulation of cell cycle checkpoint(GO:1901976) negative regulation of cell cycle checkpoint(GO:1901977) regulation of DNA damage checkpoint(GO:2000001) negative regulation of DNA damage checkpoint(GO:2000002) negative regulation of response to DNA damage stimulus(GO:2001021)
0.1 1.0 GO:0046513 ceramide metabolic process(GO:0006672) ceramide biosynthetic process(GO:0046513)
0.1 1.0 GO:0005992 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.1 0.4 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.1 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.1 0.6 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 3.4 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.1 0.4 GO:0006673 inositolphosphoceramide metabolic process(GO:0006673)
0.1 2.4 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 0.9 GO:1902707 glucose catabolic process(GO:0006007) glycolytic fermentation to ethanol(GO:0019655) glycolytic fermentation(GO:0019660) hexose catabolic process to ethanol(GO:1902707)
0.1 0.1 GO:0033559 unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559)
0.1 1.0 GO:0006272 leading strand elongation(GO:0006272)
0.1 1.0 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.4 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.4 GO:0006798 polyphosphate catabolic process(GO:0006798)
0.1 0.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.1 1.1 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.1 0.6 GO:0046219 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.1 1.4 GO:0007120 axial cellular bud site selection(GO:0007120)
0.1 0.4 GO:0048279 vesicle fusion with endoplasmic reticulum(GO:0048279)
0.1 0.3 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.1 0.3 GO:0006721 terpenoid metabolic process(GO:0006721) terpenoid biosynthetic process(GO:0016114) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.3 GO:0019419 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.1 2.3 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.2 GO:0019408 polyprenol metabolic process(GO:0016093) polyprenol biosynthetic process(GO:0016094) dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.1 GO:0071478 cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482)
0.1 0.9 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 1.3 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.2 GO:0070827 chromatin maintenance(GO:0070827)
0.1 0.3 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.1 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.1 0.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.6 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 0.2 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.5 GO:0046655 folic acid metabolic process(GO:0046655) folic acid biosynthetic process(GO:0046656)
0.1 0.3 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 1.3 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.2 GO:0046831 regulation of mRNA export from nucleus(GO:0010793) regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831) regulation of ribonucleoprotein complex localization(GO:2000197)
0.1 0.4 GO:0048313 Golgi inheritance(GO:0048313)
0.1 0.6 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.1 0.3 GO:0007535 donor selection(GO:0007535)
0.1 0.7 GO:0000376 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.1 1.0 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.1 0.3 GO:0007329 positive regulation of transcription from RNA polymerase II promoter by pheromones(GO:0007329) positive regulation of transcription by pheromones(GO:0009371)
0.1 0.1 GO:0006760 folic acid-containing compound metabolic process(GO:0006760) folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound metabolic process(GO:0042558) pteridine-containing compound biosynthetic process(GO:0042559)
0.1 2.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of metal ion(GO:0051238) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.4 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.6 GO:0006901 vesicle coating(GO:0006901)
0.1 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
0.1 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.4 GO:0009304 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 1.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.6 GO:0071966 fungal-type cell wall chitin biosynthetic process(GO:0034221) fungal-type cell wall polysaccharide biosynthetic process(GO:0051278) fungal-type cell wall polysaccharide metabolic process(GO:0071966)
0.1 0.3 GO:0007234 osmosensory signaling via phosphorelay pathway(GO:0007234)
0.1 0.6 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.4 GO:0006797 polyphosphate metabolic process(GO:0006797)
0.1 0.1 GO:0051225 spindle assembly(GO:0051225)
0.1 0.1 GO:0071049 nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.1 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.1 GO:0032368 regulation of lipid transport(GO:0032368)
0.1 0.7 GO:0043094 cellular metabolic compound salvage(GO:0043094)
0.1 1.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.2 GO:0040031 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:0060491 regulation of cell projection organization(GO:0031344) regulation of mating projection assembly(GO:0031383) regulation of cell projection assembly(GO:0060491)
0.1 0.3 GO:0035376 sterol import(GO:0035376)
0.1 0.1 GO:0042710 biofilm formation(GO:0042710)
0.1 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0043470 regulation of carbohydrate catabolic process(GO:0043470) regulation of cellular carbohydrate catabolic process(GO:0043471)
0.1 0.2 GO:0015883 FAD transport(GO:0015883)
0.1 0.4 GO:0043666 regulation of phosphatase activity(GO:0010921) regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 1.4 GO:0045047 protein targeting to ER(GO:0045047)
0.1 0.4 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 1.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 0.6 GO:0055070 cellular copper ion homeostasis(GO:0006878) copper ion homeostasis(GO:0055070)
0.1 0.4 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.2 GO:0051707 immune effector process(GO:0002252) immune system process(GO:0002376) response to virus(GO:0009615) response to external biotic stimulus(GO:0043207) defense response to virus(GO:0051607) response to other organism(GO:0051707) defense response to other organism(GO:0098542)
0.1 0.2 GO:0033241 regulation of cellular amine catabolic process(GO:0033241)
0.1 0.6 GO:0006415 translational termination(GO:0006415)
0.1 0.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.0 GO:0016129 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.0 0.0 GO:0061412 positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation(GO:0061412)
0.0 0.2 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 0.3 GO:0030847 termination of RNA polymerase II transcription, exosome-dependent(GO:0030847)
0.0 0.5 GO:0015833 peptide transport(GO:0015833)
0.0 0.1 GO:0009097 isoleucine biosynthetic process(GO:0009097)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.6 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 2.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.4 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.0 0.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0031684 heterotrimeric G-protein complex cycle(GO:0031684)
0.0 0.2 GO:0042173 regulation of sporulation resulting in formation of a cellular spore(GO:0042173)
0.0 0.6 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.1 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
0.0 0.1 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:0015918 sterol transport(GO:0015918)
0.0 0.1 GO:0001109 promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111)
0.0 0.0 GO:0006952 defense response(GO:0006952)
0.0 0.1 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0009088 threonine biosynthetic process(GO:0009088)
0.0 0.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.1 GO:0009756 cellular glucose homeostasis(GO:0001678) carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.1 GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.0 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:1902749 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.9 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.1 GO:0090220 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0 0.2 GO:0006276 plasmid maintenance(GO:0006276)
0.0 1.3 GO:0007015 actin filament organization(GO:0007015)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.2 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.4 GO:0051666 actin cortical patch localization(GO:0051666)
0.0 0.2 GO:0000741 karyogamy(GO:0000741) karyogamy involved in conjugation with cellular fusion(GO:0000742)
0.0 0.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0010970 establishment of localization by movement along microtubule(GO:0010970) nuclear migration along microtubule(GO:0030473) organelle transport along microtubule(GO:0072384)
0.0 0.4 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.6 GO:0015748 organophosphate ester transport(GO:0015748)
0.0 0.0 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0 0.0 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.7 GO:0046467 membrane lipid biosynthetic process(GO:0046467)
0.0 0.1 GO:0030308 negative regulation of cell growth(GO:0030308) negative regulation of pseudohyphal growth(GO:2000221)
0.0 0.0 GO:1900062 regulation of cell aging(GO:0090342) regulation of replicative cell aging(GO:1900062)
0.0 0.7 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.0 GO:0035392 maintenance of chromatin silencing(GO:0006344) maintenance of chromatin silencing at telomere(GO:0035392)
0.0 0.1 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0031134 sister chromatid biorientation(GO:0031134)
0.0 0.1 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0000105 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.5 GO:0051445 regulation of meiotic nuclear division(GO:0040020) regulation of meiotic cell cycle(GO:0051445)
0.0 1.0 GO:0006364 rRNA processing(GO:0006364)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0036213 actomyosin contractile ring contraction(GO:0000916) contractile ring contraction(GO:0036213)
0.0 0.0 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 1.7 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.0 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.2 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.1 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.1 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0030466 chromatin silencing at silent mating-type cassette(GO:0030466)
0.0 0.0 GO:0032970 regulation of actin cytoskeleton organization(GO:0032956) regulation of actin filament-based process(GO:0032970)
0.0 0.0 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.5 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 1.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.0 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.2 GO:0042594 response to starvation(GO:0042594)
0.0 0.1 GO:0033673 negative regulation of protein kinase activity(GO:0006469) negative regulation of kinase activity(GO:0033673)
0.0 0.1 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.0 0.0 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001) establishment of spindle orientation(GO:0051294)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 4.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.4 1.5 GO:0032160 septin filament array(GO:0032160)
0.3 1.0 GO:0070545 PeBoW complex(GO:0070545)
0.3 0.9 GO:0033186 CAF-1 complex(GO:0033186)
0.3 1.8 GO:0005871 kinesin complex(GO:0005871)
0.3 0.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 15.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 19.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.3 GO:0005880 nuclear microtubule(GO:0005880)
0.2 1.2 GO:0034455 t-UTP complex(GO:0034455)
0.2 2.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 0.7 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.2 0.7 GO:0070209 ASTRA complex(GO:0070209)
0.2 3.0 GO:0016586 RSC complex(GO:0016586)
0.2 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.7 GO:0070860 RNA polymerase I core factor complex(GO:0070860)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.6 GO:0033179 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 2.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.9 GO:0032126 eisosome(GO:0032126)
0.1 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.9 GO:0000346 transcription export complex(GO:0000346)
0.1 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.4 GO:0000243 commitment complex(GO:0000243)
0.1 2.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.6 GO:0034044 exomer complex(GO:0034044)
0.1 0.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.6 GO:0035339 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.1 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.5 GO:0031518 CBF3 complex(GO:0031518)
0.1 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.7 GO:0034456 UTP-C complex(GO:0034456)
0.1 0.3 GO:0031415 NatA complex(GO:0031415)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.2 GO:0005940 septin ring(GO:0005940)
0.1 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.3 GO:0097344 Rix1 complex(GO:0097344)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.8 GO:0030118 clathrin coat(GO:0030118)
0.1 3.3 GO:0030686 90S preribosome(GO:0030686)
0.1 0.3 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.1 0.7 GO:0090544 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)
0.1 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 0.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.6 GO:0042597 periplasmic space(GO:0042597)
0.1 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.1 GO:0046930 pore complex(GO:0046930)
0.1 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0070775 NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775)
0.1 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.3 GO:0000938 GARP complex(GO:0000938)
0.1 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.3 GO:0030478 actin cap(GO:0030478)
0.1 2.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 3.5 GO:0005816 microtubule organizing center(GO:0005815) spindle pole body(GO:0005816)
0.1 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.0 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.4 GO:0005884 actin filament(GO:0005884)
0.1 0.3 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0044697 HICS complex(GO:0044697)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205) Sec62/Sec63 complex(GO:0031207)
0.0 0.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 2.6 GO:0044445 cytosolic part(GO:0044445)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791) rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0030894 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.8 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 5.5 GO:0005730 nucleolus(GO:0005730)
0.0 1.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.5 GO:0000131 incipient cellular bud site(GO:0000131)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0000792 heterochromatin(GO:0000792)
0.0 0.3 GO:0034708 methyltransferase complex(GO:0034708)
0.0 0.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.1 GO:0043529 GET complex(GO:0043529)
0.0 0.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 1.9 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0036452 ESCRT complex(GO:0036452)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 2.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0070210 Rpd3L-Expanded complex(GO:0070210)
0.0 0.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0000922 spindle pole(GO:0000922)
0.0 1.9 GO:0005829 cytosol(GO:0005829)
0.0 0.0 GO:0000113 nucleotide-excision repair factor 4 complex(GO:0000113)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.5 GO:0043332 mating projection tip(GO:0043332)
0.0 0.0 GO:0031389 Rad17 RFC-like complex(GO:0031389)
0.0 0.1 GO:0033176 vacuolar proton-transporting V-type ATPase complex(GO:0016471) proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.9 2.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.7 4.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.7 2.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.6 2.4 GO:0015146 pentose transmembrane transporter activity(GO:0015146)
0.5 2.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.5 1.9 GO:0016417 S-acyltransferase activity(GO:0016417)
0.4 2.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.4 1.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.3 2.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 0.8 GO:0009922 fatty acid elongase activity(GO:0009922)
0.3 1.1 GO:0004338 glucan exo-1,3-beta-glucosidase activity(GO:0004338)
0.3 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 1.0 GO:1904680 peptide transmembrane transporter activity(GO:1904680)
0.3 0.8 GO:0097617 RNA strand annealing activity(GO:0033592) annealing activity(GO:0097617)
0.2 0.7 GO:0004805 trehalose-phosphatase activity(GO:0004805)
0.2 0.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.2 0.7 GO:0016872 intramolecular lyase activity(GO:0016872)
0.2 0.9 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 1.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 0.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.6 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.2 0.6 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.2 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 2.9 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.2 0.8 GO:0043139 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 34.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 0.7 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.2 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.2 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.2 0.7 GO:0001186 core promoter sequence-specific DNA binding(GO:0001046) transcription factor activity, RNA polymerase I transcription factor recruiting(GO:0001186)
0.2 0.6 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 2.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.2 GO:0019901 protein kinase binding(GO:0019901)
0.1 0.4 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 1.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.4 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.5 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 2.0 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.6 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.3 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.4 GO:0001167 RNA polymerase I transcription factor activity, sequence-specific DNA binding(GO:0001167) transcription factor activity, RNA polymerase I upstream control element sequence-specific binding(GO:0001168)
0.1 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.5 GO:0016408 C-acyltransferase activity(GO:0016408)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 3.3 GO:0051540 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 2.0 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.3 GO:0072341 modified amino acid binding(GO:0072341)
0.1 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.6 GO:0031386 protein tag(GO:0031386)
0.1 0.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 2.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 1.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.3 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.1 0.3 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.4 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 2.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 3.1 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.7 GO:0004497 monooxygenase activity(GO:0004497)
0.1 0.2 GO:0003951 NAD+ kinase activity(GO:0003951) NADH kinase activity(GO:0042736)
0.1 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 3.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296) single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.3 GO:0008252 nucleotidase activity(GO:0008252)
0.1 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.9 GO:0019843 rRNA binding(GO:0019843)
0.1 1.0 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 1.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.2 GO:0042973 glucan endo-1,3-beta-D-glucosidase activity(GO:0042973)
0.1 0.5 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 4.1 GO:0003924 GTPase activity(GO:0003924)
0.1 0.3 GO:0016886 cyclic-nucleotide phosphodiesterase activity(GO:0004112) ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 0.2 GO:0019206 nucleoside kinase activity(GO:0019206)
0.1 0.5 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 2.2 GO:0042393 histone binding(GO:0042393)
0.1 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 1.6 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078) signaling adaptor activity(GO:0035591)
0.1 0.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.2 GO:0015188 L-tyrosine transmembrane transporter activity(GO:0005302) L-glutamine transmembrane transporter activity(GO:0015186) L-isoleucine transmembrane transporter activity(GO:0015188) branched-chain amino acid transmembrane transporter activity(GO:0015658)
0.0 0.1 GO:0008308 anion channel activity(GO:0005253) voltage-gated anion channel activity(GO:0008308) porin activity(GO:0015288) wide pore channel activity(GO:0022829)
0.0 0.3 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 0.4 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.0 0.1 GO:0015645 long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645)
0.0 0.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0015079 potassium ion transmembrane transporter activity(GO:0015079)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.9 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.0 0.5 GO:0016769 transaminase activity(GO:0008483) transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0032934 steroid binding(GO:0005496) sterol binding(GO:0032934)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0004691 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0001139 transcription factor activity, core RNA polymerase II recruiting(GO:0001139)
0.0 1.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 1.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.7 GO:0003779 actin binding(GO:0003779)
0.0 0.2 GO:0019904 protein domain specific binding(GO:0019904)
0.0 2.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.4 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.0 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.4 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.0 GO:0019207 kinase regulator activity(GO:0019207)
0.0 0.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.0 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.0 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 2.6 GO:0003723 RNA binding(GO:0003723)
0.0 0.0 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.2 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 0.1 GO:0042123 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 PID SHP2 PATHWAY SHP2 signaling
0.3 0.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.3 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 0.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 0.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
0.6 5.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.5 2.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.3 4.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 0.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 1.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.2 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 0.6 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
0.1 0.4 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.1 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME M G1 TRANSITION Genes involved in M/G1 Transition
0.0 0.2 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.1 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.3 REACTOME CELL CYCLE MITOTIC Genes involved in Cell Cycle, Mitotic
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane