Motif ID: AAGGCAC

Z-value: 2.655


Mature miRNA associated with seed AAGGCAC:

NamemiRBase Accession
mmu-miR-124 MIMAT0000134



Activity profile for motif AAGGCAC.

activity profile for motif AAGGCAC


Sorted Z-values histogram for motif AAGGCAC

Sorted Z-values for motif AAGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_32731648 37.822 NM_146119
Fam129b
family with sequence similarity 129, member B
chrX_-_7248403 36.131 NM_019755
Plp2
proteolipid protein 2
chr16_+_24721940 32.915 NM_001145954
Lpp
LIM domain containing preferred translocation partner in lipoma
chr4_-_40800995 32.771 NM_022305
B4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr7_+_35904310 31.310 NM_007678
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr7_+_3290516 29.055 NM_016969
NM_001093765
Myadm

myeloid-associated differentiation marker

chr2_+_35137898 28.301 NM_146120
Gsn
gelsolin
chr11_+_75465651 28.026 NM_001080774
Myo1c
myosin IC
chr11_+_75465000 27.261 NM_008659
Myo1c
myosin IC
chr11_-_101327431 27.246 NM_012037
Vat1
vesicle amine transport protein 1 homolog (T californica)
chr16_+_24393435 26.234 NM_178665
Lpp
LIM domain containing preferred translocation partner in lipoma
chr2_-_84490827 26.207 NM_001085448
NM_001085449
NM_001085450
NM_007615
Ctnnd1



catenin (cadherin associated protein), delta 1



chr6_+_17256369 25.832 NM_007616
Cav1
caveolin 1, caveolae protein
chr2_-_84490666 24.608 NM_001085453
Ctnnd1
catenin (cadherin associated protein), delta 1
chr13_+_75844906 24.430 NM_138953
Ell2
elongation factor RNA polymerase II 2
chr17_+_64950988 24.422 NM_008549
Man2a1
mannosidase 2, alpha 1
chr1_-_155179844 24.338 NM_010683
Lamc1
laminin, gamma 1
chr7_+_3293008 24.324 NM_001093766
Myadm
myeloid-associated differentiation marker
chr15_-_89011113 24.205 NM_138749
Plxnb2
plexin B2
chr13_+_5860701 24.154 NM_011803
Klf6
Kruppel-like factor 6
chr16_+_24448176 24.102 NM_001145952
Lpp
LIM domain containing preferred translocation partner in lipoma
chr13_-_60278859 23.343 NM_008086
Gas1
growth arrest specific 1
chr11_+_75469516 23.069 NM_001080775
Myo1c
myosin IC
chr2_+_13495931 23.030 NM_011701
Vim
vimentin
chr6_+_97941776 22.499 NM_008601
Mitf
microphthalmia-associated transcription factor
chr14_+_75536138 22.439 NM_008879
Lcp1
lymphocyte cytosolic protein 1
chr7_+_52273317 22.189 NM_009101
Rras
Harvey rat sarcoma oncogene, subgroup R
chr7_+_3289029 22.062 NM_001093764
Myadm
myeloid-associated differentiation marker
chr6_+_97879810 21.715 NM_001178049
Mitf
microphthalmia-associated transcription factor
chr6_+_108778633 21.223 NM_138677
Edem1
ER degradation enhancer, mannosidase alpha-like 1
chr2_-_60801248 20.799 NM_020296
Rbms1
RNA binding motif, single stranded interacting protein 1
chr1_+_74438182 20.782 NM_153088
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr11_-_76660476 20.636 NM_007754
Cpd
carboxypeptidase D
chr6_+_97757012 20.507 NM_001113198
Mitf
microphthalmia-associated transcription factor
chr15_-_89004279 20.448 NM_001159521
Plxnb2
plexin B2
chr15_+_102236709 20.435 NM_013672
Sp1
trans-acting transcription factor 1
chr8_-_11312729 20.333 NM_009931
Col4a1
collagen, type IV, alpha 1
chr8_+_130882920 20.118 NM_008737
Nrp1
neuropilin 1
chr1_-_158604396 19.915 NM_023141
Tor3a
torsin family 3, member A
chr10_+_57857120 19.860 NM_001193303
Lims1
LIM and senescent cell antigen-like domains 1
chr10_-_8605668 19.525 NM_175155
Sash1
SAM and SH3 domain containing 1
chr9_+_122260733 19.088 NM_026179
Abhd5
abhydrolase domain containing 5
chr2_-_60719361 18.982 NM_001141931
NM_001141932
Rbms1

RNA binding motif, single stranded interacting protein 1

chr2_-_73367455 18.839 NM_153138
Wipf1
WAS/WASL interacting protein family, member 1
chr2_+_127951773 18.630 NM_009754
NM_207680
NM_207681
Bcl2l11


BCL2-like 11 (apoptosis facilitator)


chr19_-_44482138 18.570 NM_009127
Scd1
stearoyl-Coenzyme A desaturase 1
chr6_-_86743518 18.451 NM_013471
Anxa4
annexin A4
chr9_-_43047862 18.386 NM_178644
Oaf
OAF homolog (Drosophila)
chr4_+_61947463 18.259 NM_025286
Slc31a2
solute carrier family 31, member 2
chr17_+_87362450 18.156 NM_145491
Rhoq
ras homolog gene family, member Q
chr5_+_32438843 18.151 NM_008037
Fosl2
fos-like antigen 2
chr8_+_47556353 18.125 NM_007981
Acsl1
acyl-CoA synthetase long-chain family member 1
chr16_+_37777075 18.046 NM_008047
Fstl1
follistatin-like 1
chr19_-_6015778 17.816 NM_001110504
Capn1
calpain 1
chr10_+_57834201 17.796 NM_201242
Lims1
LIM and senescent cell antigen-like domains 1
chr10_+_57786213 17.649 NM_026148
Lims1
LIM and senescent cell antigen-like domains 1
chr7_+_148654681 17.250 NM_001111050
Cd151
CD151 antigen
chrX_+_136145155 17.239 NM_023270
Rnf128
ring finger protein 128
chr1_+_127457542 17.045 NM_028787
Slc35f5
solute carrier family 35, member F5
chr4_-_59562054 16.971 NM_144904
NM_178164
Rod1

ROD1 regulator of differentiation 1 (S. pombe)

chr15_-_67008433 16.750 NM_009177
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr19_+_7568529 16.719 NM_001163505
Atl3
atlastin GTPase 3
chr3_-_36374739 16.673 NM_009673
Anxa5
annexin A5
chr9_-_21722533 16.579 NM_031874
Rab3d
RAB3D, member RAS oncogene family
chr3_-_58329780 16.501 NM_030685
Serp1
stress-associated endoplasmic reticulum protein 1
chr15_-_76039082 16.363 NM_201387
Plec
plectin
chr10_-_66559568 16.331 NM_178606
Reep3
receptor accessory protein 3
chr2_-_136942066 16.307 NM_013822
Jag1
jagged 1
chr3_-_131047840 16.128 NM_028943
Sgms2
sphingomyelin synthase 2
chr12_+_81891479 16.096 NM_178682
4933426M11Rik
RIKEN cDNA 4933426M11 gene
chr10_-_7500674 15.928 NM_145418
BC013529
cDNA sequence BC013529
chr8_+_28196312 15.918 NM_054044
Gpr124
G protein-coupled receptor 124
chr10_-_60610398 15.841 NM_009163
Sgpl1
sphingosine phosphate lyase 1
chr16_-_10993155 15.724 NM_019980
Litaf
LPS-induced TN factor
chr5_+_137462888 15.649 NM_011962
Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr11_-_32122259 15.629 NM_010117
Rhbdf1
rhomboid family 1 (Drosophila)
chr19_-_34601874 15.608 NM_001111100
NM_021460
Lipa

lysosomal acid lipase A

chr13_-_114408704 15.598 NM_130796
Snx18
sorting nexin 18
chrX_-_103207106 15.558 NM_001190409
NM_025952
Magt1

magnesium transporter 1

chr10_-_87819765 15.430 NM_027878
Dram1
DNA-damage regulated autophagy modulator 1
chr2_+_27532692 15.366 NM_011305
Rxra
retinoid X receptor alpha
chr15_-_76038682 15.350 NM_001164203
NM_201388
Plec

plectin

chr11_-_50105794 15.255 NM_175334
Maml1
mastermind like 1 (Drosophila)
chr19_+_42221868 15.210 NM_183195
Marveld1
MARVEL (membrane-associating) domain containing 1
chr14_+_26661614 15.193 NM_013469
Anxa11
annexin A11
chr8_+_36438761 14.985 NM_177741
Ppp1r3b
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr19_+_5637459 14.860 NM_009045
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chrX_+_156065141 14.851 NM_001135727
Sh3kbp1
SH3-domain kinase binding protein 1
chr14_-_21299301 14.760 NM_001110794
NM_009674
Anxa7

annexin A7

chr3_-_29912113 14.731 NM_007963
Mecom
MDS1 and EVI1 complex locus
chr7_-_87547589 14.729 NM_011046
Furin
furin (paired basic amino acid cleaving enzyme)
chr19_-_6015125 14.709 NM_007600
Capn1
calpain 1
chr12_-_86715612 14.599 NM_026775
Tmed10
transmembrane emp24-like trafficking protein 10 (yeast)
chr10_-_92773778 14.570 NM_013508
Elk3
ELK3, member of ETS oncogene family
chr1_-_167124442 14.495 NM_145512
Sft2d2
SFT2 domain containing 2
chr6_-_127100954 14.439 NM_009829
Ccnd2
cyclin D2
chr15_-_76031023 14.384 NM_201390
Plec
plectin
chr15_-_76059926 14.361 NM_201385
Plec
plectin
chr6_+_38383918 14.200 NM_177185
Ubn2
ubinuclein 2
chr3_+_95119155 14.166 NM_029789
Lass2
LAG1 homolog, ceramide synthase 2
chr12_-_74214214 14.147 NM_011382
Six4
sine oculis-related homeobox 4 homolog (Drosophila)
chr13_+_45485106 14.046 NM_153789
NM_181043
Mylip

myosin regulatory light chain interacting protein

chr12_+_117519658 14.041 NM_028731
Esyt2
extended synaptotagmin-like protein 2
chr7_+_71432538 13.979 NM_172742
Mtmr10
myotubularin related protein 10
chr5_+_145875080 13.922 NM_023142
Arpc1b
actin related protein 2/3 complex, subunit 1B
chr2_-_26789021 13.776 NM_011512
Surf4
surfeit gene 4
chr15_-_76039510 13.767 NM_201386
Plec
plectin
chr1_+_140860285 13.759 NM_001166501
Dennd1b
DENN/MADD domain containing 1B
chr7_-_87550315 13.669 NM_001081454
Furin
furin (paired basic amino acid cleaving enzyme)
chr11_+_117127516 13.659 NM_001113487
Sept9
septin 9
chr3_-_115710131 13.637 NM_023214
Slc30a7
solute carrier family 30 (zinc transporter), member 7
chrX_+_156146532 13.588 NM_021389
Sh3kbp1
SH3-domain kinase binding protein 1
chr2_-_152169650 13.545 NM_175093
Trib3
tribbles homolog 3 (Drosophila)
chr6_+_116288075 13.501 NM_027920
March8
membrane-associated ring finger (C3HC4) 8
chr17_-_84587278 13.459 NM_001001806
Zfp36l2
zinc finger protein 36, C3H type-like 2
chr3_+_41367672 13.447 NM_001130185
Phf17
PHD finger protein 17
chr7_+_114738564 13.390 NM_008905
Ppfibp2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr16_+_14705932 13.350 NM_011415
Snai2
snail homolog 2 (Drosophila)
chr10_+_95403283 13.307 NM_001001932
Eea1
early endosome antigen 1
chr16_-_45844409 13.287 NM_153412
Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_+_27388907 13.285 NM_001025615
NM_026202
Ccdc50

coiled-coil domain containing 50

chr9_+_118835589 13.121 NM_133710
Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr14_-_22808822 13.100 NM_145459
Zfp503
zinc finger protein 503
chr4_+_62021728 12.969 NM_175090
Slc31a1
solute carrier family 31, member 1
chr7_+_119822831 12.941 NM_001166584
NM_009346
Tead1

TEA domain family member 1

chr18_+_5046584 12.937 NM_153153
Svil
supervillin
chr5_-_115140869 12.837 NM_019821
Gltp
glycolipid transfer protein
chr15_-_73015345 12.814 NM_153178
Eif2c2
eukaryotic translation initiation factor 2C, 2
chr6_-_119367498 12.765 NM_197985
Adipor2
adiponectin receptor 2
chr17_+_28828286 12.760 NM_001168508
NM_001168514
NM_011951
Mapk14


mitogen-activated protein kinase 14


chr3_+_41367304 12.718 NM_172303
Phf17
PHD finger protein 17
chrX_+_68463941 12.713 NM_001164190
Mtm1
X-linked myotubular myopathy gene 1
chr15_-_76036745 12.689 NM_001163540
NM_201389
Plec

plectin

chr10_+_58786043 12.646 NM_011030
P4ha1
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
chr9_-_79566271 12.610 NM_007730
Col12a1
collagen, type XII, alpha 1
chr15_-_76061807 12.534 NM_001163542
NM_011117
Plec

plectin

chr12_+_112278008 12.514 NM_198023
Rcor1
REST corepressor 1
chr10_+_11001072 12.468 NM_027968
Fbxo30
F-box protein 30
chr2_-_142727172 12.454 NM_001081133
Kif16b
kinesin family member 16B
chr11_+_78001871 12.341 NM_001159482
Rab34
RAB34, member of RAS oncogene family
chr6_-_137597616 12.299 NM_007945
Eps8
epidermal growth factor receptor pathway substrate 8
chr14_-_119105434 12.219 NM_001033336
NM_001163676
Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chrX_+_103222548 12.169 NM_001109757
NM_009726
Atp7a

ATPase, Cu++ transporting, alpha polypeptide

chr15_-_76030264 12.097 NM_001163549
NM_201391
Plec

plectin

chr12_+_33638809 12.056 NM_013635
Sypl
synaptophysin-like protein
chr11_+_78002249 12.047 NM_033475
Rab34
RAB34, member of RAS oncogene family
chr4_+_139131050 12.024 NM_183148
Iffo2
intermediate filament family orphan 2
chr4_+_97248556 12.008 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr6_-_92851434 11.935 NM_175314
Adamts9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
chr10_+_11001384 11.923 NM_001168297
Fbxo30
F-box protein 30
chr11_+_109224104 11.910 NM_010303
Gna13
guanine nucleotide binding protein, alpha 13
chr5_-_98459943 11.891 NM_133738
Antxr2
anthrax toxin receptor 2
chr4_-_154596628 11.836 NM_011385
Ski
ski sarcoma viral oncogene homolog (avian)
chr11_+_117193594 11.808 NM_001113488
Sept9
septin 9
chr16_+_35938555 11.801 NM_030253
Parp9
poly (ADP-ribose) polymerase family, member 9
chr11_+_81849074 11.709 NM_011333
Ccl2
chemokine (C-C motif) ligand 2
chr14_-_35315715 11.579 NM_009758
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr4_-_10934608 11.572 NM_175175
Plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr12_+_33639034 11.571 NM_198710
Sypl
synaptophysin-like protein
chr15_-_79233664 11.571 NM_172608
Tmem184b
transmembrane protein 184b
chr2_+_119373442 11.515 NM_019769
1500003O03Rik
RIKEN cDNA 1500003O03 gene
chr9_-_107537602 11.470 NM_008138
Gnai2
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr1_-_54983211 11.463 NM_001081433
Ankrd44
ankyrin repeat domain 44
chr15_-_76028594 11.378 NM_201393
Plec
plectin
chr3_-_143865162 11.372 NM_001161770
NM_001161769
Lmo4

LIM domain only 4

chr5_+_73305509 11.369 NM_001113423
NM_153567
Slain2

SLAIN motif family, member 2

chr18_+_20716598 11.330 NM_007883
Dsg2
desmoglein 2
chr8_+_81033220 11.322 NM_029736
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr10_+_126432666 11.299 NM_146012
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr3_-_130974850 11.272 NM_008212
Hadh
hydroxyacyl-Coenzyme A dehydrogenase
chr14_-_119076152 11.260 NM_001163675
Abcc4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr5_-_30481492 11.234 NM_178878
Hadha
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
chrX_-_71330931 11.142 NM_010788
NM_001081979
Mecp2

methyl CpG binding protein 2

chr6_-_134516930 11.124 NM_008514
Lrp6
low density lipoprotein receptor-related protein 6
chr15_-_76029835 11.086 NM_201392
Plec
plectin
chr18_-_39646734 11.046 NM_008173
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr8_+_109459623 11.044 NM_009229
Sntb2
syntrophin, basic 2
chr19_-_10956160 10.977 NM_134142
Tmem109
transmembrane protein 109
chr15_+_97614772 10.938 NM_026353
Slc48a1
solute carrier family 48 (heme transporter), member 1
chr2_+_4073908 10.910 NM_172475
Frmd4a
FERM domain containing 4A
chr6_+_124613114 10.893 NM_145130
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr1_+_62749850 10.885 NM_001077403
NM_001077404
NM_001077405
NM_001077406
NM_001077407
NM_010939
Nrp2





neuropilin 2





chr5_+_93522440 10.876 NM_001009818
Sept11
septin 11
chr11_-_62462024 10.851 NM_198861
BC046404
cDNA sequence BC046404
chr3_-_89197124 10.840 NM_009565
Zbtb7b
zinc finger and BTB domain containing 7B
chr19_+_4125894 10.837 NM_001078649
NM_025889
Tmem134

transmembrane protein 134

chr2_-_143836838 10.823 NM_024281
NM_133626
Rrbp1

ribosome binding protein 1

chr4_-_134323845 10.788 NM_145554
Ldlrap1
low density lipoprotein receptor adaptor protein 1
chr19_+_3323262 10.715 NM_013495
Cpt1a
carnitine palmitoyltransferase 1a, liver
chr16_-_59555577 10.676 NM_174848
Crybg3
beta-gamma crystallin domain containing 3
chr3_+_41368801 10.673 NM_001130186
Phf17
PHD finger protein 17
chrX_+_53599573 10.557 NM_030139
Zfp449
zinc finger protein 449
chr7_-_87948093 10.505 NM_016721
Iqgap1
IQ motif containing GTPase activating protein 1
chr17_+_15841889 10.499 NM_007690
Chd1
chromodomain helicase DNA binding protein 1
chr4_+_147314951 10.489 NM_029841
2510039O18Rik
RIKEN cDNA 2510039O18 gene
chr11_+_69659873 10.442 NM_001168497
Plscr3
phospholipid scramblase 3
chr12_+_33063653 10.362 NM_001162903
2010109K11Rik
RIKEN cDNA 2010109K11 gene
chr4_+_118102305 10.352 NM_001039176
Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr12_-_36219651 10.207 NM_013464
Ahr
aryl-hydrocarbon receptor
chr8_+_126177709 10.191 NM_133955
Rhou
ras homolog gene family, member U

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.62 2.03e-15 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.46 2.07e-14 GO:0044237 cellular metabolic process
1.67 2.73e-13 GO:0031323 regulation of cellular metabolic process
2.62 6.23e-13 GO:0010628 positive regulation of gene expression
2.23 7.45e-13 GO:0031325 positive regulation of cellular metabolic process
1.60 1.12e-12 GO:0019222 regulation of metabolic process
2.69 1.18e-12 GO:0045893 positive regulation of transcription, DNA-dependent
2.17 1.73e-12 GO:0009893 positive regulation of metabolic process
1.65 1.87e-12 GO:0080090 regulation of primary metabolic process
2.65 2.79e-12 GO:0051254 positive regulation of RNA metabolic process
1.42 4.10e-12 GO:0044238 primary metabolic process
2.52 4.21e-12 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.19 8.62e-12 GO:0010604 positive regulation of macromolecule metabolic process
1.75 9.05e-12 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.49 9.78e-12 GO:0010557 positive regulation of macromolecule biosynthetic process
1.74 1.22e-11 GO:0051171 regulation of nitrogen compound metabolic process
2.46 1.82e-11 GO:0051173 positive regulation of nitrogen compound metabolic process
1.73 3.33e-11 GO:0048518 positive regulation of biological process
1.76 7.79e-11 GO:0048522 positive regulation of cellular process
2.37 8.26e-11 GO:0031328 positive regulation of cellular biosynthetic process
2.84 9.48e-11 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.79 9.71e-11 GO:0051252 regulation of RNA metabolic process
1.73 2.22e-10 GO:0010556 regulation of macromolecule biosynthetic process
1.70 2.31e-10 GO:0009889 regulation of biosynthetic process
1.72 2.43e-10 GO:0010468 regulation of gene expression
2.32 2.56e-10 GO:0009891 positive regulation of biosynthetic process
1.35 3.33e-10 GO:0008152 metabolic process
1.74 4.04e-10 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.61 4.51e-10 GO:0060255 regulation of macromolecule metabolic process
1.70 5.59e-10 GO:0031326 regulation of cellular biosynthetic process
1.77 6.62e-10 GO:0006355 regulation of transcription, DNA-dependent
1.79 2.03e-09 GO:0048523 negative regulation of cellular process
1.73 5.45e-09 GO:0048519 negative regulation of biological process
1.46 1.33e-08 GO:0044260 cellular macromolecule metabolic process
1.58 2.16e-08 GO:0051179 localization
1.84 2.21e-08 GO:0048513 organ development
1.59 2.23e-08 GO:0009058 biosynthetic process
1.20 2.78e-08 GO:0009987 cellular process
1.68 4.97e-08 GO:0048731 system development
2.15 5.46e-08 GO:0006796 phosphate metabolic process
2.15 6.08e-08 GO:0006793 phosphorus metabolic process
1.59 1.37e-07 GO:0007275 multicellular organismal development
1.55 1.61e-07 GO:0032502 developmental process
1.62 1.73e-07 GO:0006810 transport
1.93 1.82e-07 GO:0009653 anatomical structure morphogenesis
1.62 1.88e-07 GO:0051234 establishment of localization
1.57 2.00e-07 GO:0044249 cellular biosynthetic process
1.59 7.98e-07 GO:0048856 anatomical structure development
1.97 9.16e-07 GO:0033036 macromolecule localization
2.07 9.50e-07 GO:0043067 regulation of programmed cell death
2.07 1.28e-06 GO:0042981 regulation of apoptosis
2.05 1.42e-06 GO:0010941 regulation of cell death
1.38 1.69e-06 GO:0043170 macromolecule metabolic process
1.76 1.73e-06 GO:0006351 transcription, DNA-dependent
1.75 1.93e-06 GO:0032774 RNA biosynthetic process
3.15 4.09e-06 GO:0007264 small GTPase mediated signal transduction
1.46 7.85e-06 GO:0006807 nitrogen compound metabolic process
2.46 9.72e-06 GO:0072358 cardiovascular system development
2.46 9.72e-06 GO:0072359 circulatory system development
1.53 1.13e-05 GO:0016043 cellular component organization
1.74 1.24e-05 GO:0006464 protein modification process
2.31 2.10e-05 GO:0044255 cellular lipid metabolic process
1.45 3.14e-05 GO:0034641 cellular nitrogen compound metabolic process
1.71 4.40e-05 GO:0044281 small molecule metabolic process
1.69 4.92e-05 GO:0043412 macromolecule modification
1.55 6.68e-05 GO:0009059 macromolecule biosynthetic process
1.84 7.22e-05 GO:0009966 regulation of signal transduction
2.07 7.91e-05 GO:0015031 protein transport
2.06 7.97e-05 GO:0045184 establishment of protein localization
12.96 8.47e-05 GO:0032365 intracellular lipid transport
1.48 9.04e-05 GO:0071840 cellular component organization or biogenesis
1.89 1.09e-04 GO:0035556 intracellular signal transduction
1.54 1.19e-04 GO:0034645 cellular macromolecule biosynthetic process
1.45 1.27e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.02 1.65e-04 GO:0006629 lipid metabolic process
2.04 2.20e-04 GO:0009890 negative regulation of biosynthetic process
4.42 2.22e-04 GO:0007265 Ras protein signal transduction
1.68 2.41e-04 GO:0048583 regulation of response to stimulus
2.68 2.54e-04 GO:0001944 vasculature development
2.76 3.12e-04 GO:0001568 blood vessel development
2.43 3.36e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.42 3.59e-04 GO:0061024 membrane organization
2.05 3.70e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.53 3.82e-04 GO:0016070 RNA metabolic process
1.71 4.01e-04 GO:0023051 regulation of signaling
2.95 4.22e-04 GO:0048514 blood vessel morphogenesis
2.02 4.96e-04 GO:0031327 negative regulation of cellular biosynthetic process
2.14 5.75e-04 GO:0046907 intracellular transport
1.92 6.22e-04 GO:0009888 tissue development
2.38 8.52e-04 GO:0016044 cellular membrane organization
1.56 8.98e-04 GO:0048869 cellular developmental process
1.94 9.58e-04 GO:0016310 phosphorylation
1.57 9.87e-04 GO:0030154 cell differentiation
2.28 1.36e-03 GO:0043069 negative regulation of programmed cell death
1.90 1.64e-03 GO:0051649 establishment of localization in cell
3.21 1.70e-03 GO:0016311 dephosphorylation
2.69 1.91e-03 GO:0001501 skeletal system development
1.81 1.93e-03 GO:0008104 protein localization
1.80 2.23e-03 GO:0050793 regulation of developmental process
1.47 2.23e-03 GO:0010467 gene expression
2.25 2.43e-03 GO:0043066 negative regulation of apoptosis
2.90 2.49e-03 GO:0030036 actin cytoskeleton organization
1.99 2.61e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.05 2.74e-03 GO:0051253 negative regulation of RNA metabolic process
1.50 2.99e-03 GO:0044267 cellular protein metabolic process
2.04 4.02e-03 GO:0045892 negative regulation of transcription, DNA-dependent
2.19 4.02e-03 GO:0060548 negative regulation of cell death
1.21 4.50e-03 GO:0050794 regulation of cellular process
2.81 4.53e-03 GO:0006631 fatty acid metabolic process
2.01 4.88e-03 GO:0012501 programmed cell death
1.96 5.00e-03 GO:0006468 protein phosphorylation
2.48 7.24e-03 GO:0032787 monocarboxylic acid metabolic process
1.95 7.24e-03 GO:0010629 negative regulation of gene expression
2.20 7.64e-03 GO:0007010 cytoskeleton organization
2.72 8.03e-03 GO:0030029 actin filament-based process
1.94 8.64e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19 8.93e-03 GO:0065007 biological regulation
2.15 1.10e-02 GO:0071310 cellular response to organic substance
1.76 1.14e-02 GO:0031324 negative regulation of cellular metabolic process
2.87 1.23e-02 GO:0032870 cellular response to hormone stimulus
2.55 1.25e-02 GO:0031329 regulation of cellular catabolic process
3.14 1.28e-02 GO:0048705 skeletal system morphogenesis
1.75 1.32e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.91 1.33e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.97 1.43e-02 GO:0006915 apoptosis
1.96 1.49e-02 GO:0009887 organ morphogenesis
1.19 1.54e-02 GO:0050789 regulation of biological process
2.08 1.71e-02 GO:0043009 chordate embryonic development
1.72 1.96e-02 GO:0051641 cellular localization
2.04 2.32e-02 GO:0048646 anatomical structure formation involved in morphogenesis
2.05 2.42e-02 GO:0009792 embryo development ending in birth or egg hatching
1.88 2.46e-02 GO:0008219 cell death
2.68 2.54e-02 GO:0048732 gland development
3.22 2.59e-02 GO:0006869 lipid transport
1.70 2.66e-02 GO:0032879 regulation of localization
1.69 2.70e-02 GO:0009892 negative regulation of metabolic process
19.43 2.95e-02 GO:0006686 sphingomyelin biosynthetic process
1.75 3.00e-02 GO:0042127 regulation of cell proliferation
1.86 3.28e-02 GO:0016265 death
1.79 3.29e-02 GO:0009790 embryo development
1.39 3.32e-02 GO:0090304 nucleic acid metabolic process
3.04 3.43e-02 GO:0019216 regulation of lipid metabolic process
1.81 3.45e-02 GO:0045595 regulation of cell differentiation
1.93 3.56e-02 GO:0016192 vesicle-mediated transport
1.95 4.38e-02 GO:0001932 regulation of protein phosphorylation
1.88 4.39e-02 GO:0070887 cellular response to chemical stimulus
1.67 4.80e-02 GO:0010033 response to organic substance
2.64 4.86e-02 GO:0071495 cellular response to endogenous stimulus

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.42 2.80e-37 GO:0005622 intracellular
1.43 4.62e-36 GO:0044424 intracellular part
1.45 8.09e-29 GO:0043226 organelle
1.45 1.80e-28 GO:0043229 intracellular organelle
1.50 1.42e-27 GO:0005737 cytoplasm
1.47 6.97e-25 GO:0043227 membrane-bounded organelle
1.47 8.86e-25 GO:0043231 intracellular membrane-bounded organelle
1.18 6.45e-18 GO:0005623 cell
1.18 6.45e-18 GO:0044464 cell part
1.55 1.47e-17 GO:0044444 cytoplasmic part
1.48 1.79e-11 GO:0005634 nucleus
1.48 6.17e-09 GO:0044422 organelle part
1.45 1.10e-07 GO:0044446 intracellular organelle part
1.71 3.26e-05 GO:0005829 cytosol
3.27 6.04e-05 GO:0005635 nuclear envelope
1.81 1.39e-04 GO:0005783 endoplasmic reticulum
2.32 1.64e-04 GO:0005768 endosome
1.74 1.86e-04 GO:0031090 organelle membrane
1.94 1.86e-04 GO:0012505 endomembrane system
1.85 2.23e-04 GO:0005626 insoluble fraction
1.95 2.62e-04 GO:0031982 vesicle
2.03 4.23e-04 GO:0030054 cell junction
1.20 4.52e-04 GO:0016020 membrane
1.89 1.71e-03 GO:0031410 cytoplasmic vesicle
1.64 3.73e-03 GO:0000267 cell fraction
1.51 4.16e-03 GO:0044428 nuclear part
1.74 5.91e-03 GO:0005624 membrane fraction
3.10 6.25e-03 GO:0070161 anchoring junction
3.62 9.16e-03 GO:0043296 apical junction complex
3.81 1.02e-02 GO:0031965 nuclear membrane
3.54 1.17e-02 GO:0016327 apicolateral plasma membrane
2.53 1.38e-02 GO:0016323 basolateral plasma membrane
1.67 1.44e-02 GO:0005794 Golgi apparatus
1.85 1.54e-02 GO:0031967 organelle envelope
1.48 1.94e-02 GO:0070013 intracellular organelle lumen
1.48 2.08e-02 GO:0043233 organelle lumen
1.82 2.19e-02 GO:0031975 envelope
2.44 2.39e-02 GO:0005911 cell-cell junction
1.45 2.48e-02 GO:0044459 plasma membrane part
3.01 2.53e-02 GO:0005912 adherens junction
1.34 2.99e-02 GO:0043234 protein complex
1.28 3.61e-02 GO:0071944 cell periphery
1.45 4.42e-02 GO:0031974 membrane-enclosed lumen
3.51 4.49e-02 GO:0005923 tight junction
3.51 4.49e-02 GO:0070160 occluding junction
1.28 4.64e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.32 2.74e-19 GO:0005488 binding
1.55 1.64e-18 GO:0005515 protein binding
2.07 3.40e-06 GO:0019899 enzyme binding
2.01 4.62e-05 GO:0016301 kinase activity
1.99 1.52e-04 GO:0001071 nucleic acid binding transcription factor activity
1.99 1.52e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.54 1.53e-04 GO:0000166 nucleotide binding
1.31 2.06e-04 GO:0003824 catalytic activity
2.39 2.47e-04 GO:0008289 lipid binding
1.60 2.60e-04 GO:0016740 transferase activity
2.81 2.77e-04 GO:0019901 protein kinase binding
2.59 4.41e-04 GO:0019900 kinase binding
1.38 7.43e-04 GO:0046872 metal ion binding
2.52 8.42e-04 GO:0008134 transcription factor binding
1.83 8.42e-04 GO:0030528 transcription regulator activity
1.38 8.61e-04 GO:0043167 ion binding
1.57 8.78e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.37 1.04e-03 GO:0043169 cation binding
1.55 1.29e-03 GO:0032555 purine ribonucleotide binding
1.55 1.33e-03 GO:0032553 ribonucleotide binding
1.54 1.56e-03 GO:0017076 purine nucleotide binding
2.23 2.38e-03 GO:0004674 protein serine/threonine kinase activity
1.92 2.61e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.94 3.04e-03 GO:0005543 phospholipid binding
2.64 3.22e-03 GO:0016791 phosphatase activity
1.52 4.19e-03 GO:0003677 DNA binding
1.75 4.35e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.81 5.45e-03 GO:0042802 identical protein binding
2.01 7.18e-03 GO:0008092 cytoskeletal protein binding
3.78 8.79e-03 GO:0004725 protein tyrosine phosphatase activity
1.99 9.94e-03 GO:0019904 protein domain specific binding
1.95 1.02e-02 GO:0004672 protein kinase activity
2.98 1.06e-02 GO:0004721 phosphoprotein phosphatase activity
3.37 1.78e-02 GO:0035091 phosphatidylinositol binding
1.84 1.80e-02 GO:0043565 sequence-specific DNA binding
1.76 4.23e-02 GO:0046983 protein dimerization activity
1.36 4.73e-02 GO:0003676 nucleic acid binding