Motif ID: AAUCUCA

Z-value: 0.303


Mature miRNA associated with seed AAUCUCA:

NamemiRBase Accession
mmu-miR-216a MIMAT0000662



Activity profile for motif AAUCUCA.

activity profile for motif AAUCUCA


Sorted Z-values histogram for motif AAUCUCA

Sorted Z-values for motif AAUCUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_45499599 1.914 NM_028773
Sash3
SAM and SH3 domain containing 3
chrX_+_48194578 1.456 NM_133729
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr5_-_108153337 1.365 NM_010278
Gfi1
growth factor independent 1
chr2_-_6805937 1.254 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr1_-_175297778 1.186 NM_053199
Cadm3
cell adhesion molecule 3
chr2_-_7317824 1.185 NM_001110231
Celf2
CUGBP, Elav-like family member 2
chr2_-_7002344 1.143 NM_001110229
NM_001110230
NM_001160292
Celf2


CUGBP, Elav-like family member 2


chr11_-_79337251 1.143 NM_001077496
Evi2b
ecotropic viral integration site 2b
chr2_-_7317513 1.102 NM_001110232
Celf2
CUGBP, Elav-like family member 2
chr18_-_70212948 1.066 NM_030554
Rab27b
RAB27b, member RAS oncogene family
chr9_-_66767436 1.066 NM_173413
Rab8b
RAB8B, member RAS oncogene family
chr18_-_70301202 0.923 NM_001082553
Rab27b
RAB27b, member RAS oncogene family
chrX_-_49034778 0.887 NM_001077202
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr3_+_94938009 0.883 NM_153121
Lysmd1
LysM, putative peptidoglycan-binding, domain containing 1
chr4_-_87679175 0.830 NM_027326
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrX_-_49033640 0.788 NM_015819
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr19_-_10904345 0.700 NM_001037801
NM_009852
Cd6

CD6 antigen

chr16_-_78576898 0.677 NM_025967
D16Ertd472e
DNA segment, Chr 16, ERATO Doi 472, expressed
chrX_+_68463941 0.654 NM_001164190
Mtm1
X-linked myotubular myopathy gene 1
chr4_-_87452140 0.643 NM_029931
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_-_88837850 0.639 NM_001164087
Homer2
homer homolog 2 (Drosophila)
chrX_+_68468175 0.580 NM_001164191
NM_001164192
NM_001164193
NM_019926
Mtm1



X-linked myotubular myopathy gene 1



chr7_-_88851798 0.569 NM_001164086
NM_011983
Homer2

homer homolog 2 (Drosophila)

chr5_+_35104373 0.563 NM_010414
Htt
huntingtin
chr11_-_115569814 0.548 NM_008163
Grb2
growth factor receptor bound protein 2
chr12_+_12268901 0.536 NM_001146119
NM_029758
Fam49a

family with sequence similarity 49, member A

chrX_+_133584130 0.511 NM_146261
Fam199x
family with sequence similarity 199, X-linked
chr6_+_125165597 0.506 NM_001080557
NM_009496
Vamp1

vesicle-associated membrane protein 1

chr4_-_82970054 0.499 NM_027238
Ttc39b
tetratricopeptide repeat domain 39B
chr3_+_88769733 0.497 NM_138679
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr18_-_14131046 0.497 NM_145492
Zfp521
zinc finger protein 521
chr9_-_85220730 0.494 NM_001160378
NM_001160379
Fam46a

family with sequence similarity 46, member A

chr11_+_83560437 0.488 NM_183249
1100001G20Rik
RIKEN cDNA 1100001G20 gene
chr2_+_70400179 0.488 NM_008077
Gad1
glutamic acid decarboxylase 1
chr3_+_21975544 0.486 NM_030732
Tbl1xr1
transducin (beta)-like 1X-linked receptor 1
chr11_-_118947424 0.454 NM_007625
Cbx4
chromobox homolog 4 (Drosophila Pc class)
chr10_-_101953046 0.448 NM_024435
Nts
neurotensin
chr7_+_26067197 0.447 NM_001110131
NM_001110132
NM_027882
Cic


capicua homolog (Drosophila)


chr19_-_3575695 0.446 NM_001164159
NM_028999
NM_029456
Ppp6r3


protein phosphatase 6, regulatory subunit 3


chr2_-_44968728 0.427 NM_015753
Zeb2
zinc finger E-box binding homeobox 2
chr7_-_138553991 0.426 NM_175115
Ikzf5
IKAROS family zinc finger 5
chr9_+_25060152 0.404 NM_009859
Sept7
septin 7
chr11_-_90252228 0.399 NM_172563
Hlf
hepatic leukemia factor
chr19_-_24936327 0.385 NM_175013
Pgm5
phosphoglucomutase 5
chr8_-_88214871 0.381 NM_001081324
Neto2
neuropilin (NRP) and tolloid (TLL)-like 2
chr15_-_8660729 0.378 NM_148938
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_+_66561492 0.374 NM_178396
Car12
carbonic anyhydrase 12
chr9_-_34924338 0.358 NM_009178
St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr17_+_27110101 0.338 NM_001005916
Zbtb9
zinc finger and BTB domain containing 9
chr19_+_40905768 0.338 NM_172839
Ccnj
cyclin J
chr16_+_94791713 0.333 NM_007890
Dyrk1a
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
chr7_+_52419289 0.330 NM_182993
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr19_-_28085534 0.328 NM_011265
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr2_+_118727248 0.318 NM_001045523
Bahd1
bromo adjacent homology domain containing 1
chr15_-_48623520 0.316 NM_001081391
Csmd3
CUB and Sushi multiple domains 3
chr1_+_39251056 0.307 NM_008719
Npas2
neuronal PAS domain protein 2
chr10_+_80599005 0.302 NM_010731
Zbtb7a
zinc finger and BTB domain containing 7a
chr11_+_80196766 0.296 NM_001130169
NM_001130170
NM_001130171
NM_011751
Zfp207



zinc finger protein 207



chr9_-_104165221 0.276 NM_001163026
Dnajc13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr17_-_46968361 0.276 NM_001100452
BC032203
cDNA sequence BC032203
chr16_+_94792513 0.275 NM_001113389
Dyrk1a
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
chr8_-_55615268 0.275 NM_029701
Spcs3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr9_+_27598853 0.266 NM_177906
Opcml
opioid binding protein/cell adhesion molecule-like
chr2_+_75670230 0.265 NM_172666
Agps
alkylglycerone phosphate synthase
chr16_+_33380860 0.260 NM_011749
Zfp148
zinc finger protein 148
chr14_+_112074336 0.253 NM_198865
Slitrk5
SLIT and NTRK-like family, member 5
chr6_-_39156706 0.250 NM_001033430
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr9_-_65732843 0.245 NM_001170907
Trip4
thyroid hormone receptor interactor 4
chr2_-_71384748 0.244 NM_010054
Dlx2
distal-less homeobox 2
chr7_-_36539369 0.243 NM_178704
Dpy19l3
dpy-19-like 3 (C. elegans)
chr6_+_17587046 0.239 NM_007604
Capza2
capping protein (actin filament) muscle Z-line, alpha 2
chr10_+_84218792 0.232 NM_001024918
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr10_+_106708886 0.232 NM_001033223
NM_001039354
Lin7a

lin-7 homolog A (C. elegans)

chr6_+_133985717 0.230 NM_007961
Etv6
ets variant gene 6 (TEL oncogene)
chr9_-_65756482 0.227 NM_019797
Trip4
thyroid hormone receptor interactor 4
chr9_-_95412264 0.202 NM_001114977
NM_026476
2610101N10Rik

RIKEN cDNA 2610101N10 gene

chr11_+_120094240 0.184 NM_198423
Bahcc1
BAH domain and coiled-coil containing 1
chr16_+_32914183 0.176 NM_001081255
Lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr6_+_108778633 0.175 NM_138677
Edem1
ER degradation enhancer, mannosidase alpha-like 1
chr3_-_95622554 0.174 NM_001081293
Rprd2
regulation of nuclear pre-mRNA domain containing 2
chr11_+_64248779 0.165 NM_178870
Hs3st3a1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr10_-_88720534 0.161 NM_178773
Ano4
anoctamin 4
chr15_-_34424979 0.159 NM_008287
Hrsp12
heat-responsive protein 12
chr15_-_38008565 0.157 NM_001081359
NM_001112721
Ubr5

ubiquitin protein ligase E3 component n-recognin 5

chr11_+_76718046 0.152 NM_025655
Tmigd1
transmembrane and immunoglobulin domain containing 1
chr1_+_138521477 0.149 NM_001160251
NM_177643
Zfp281

zinc finger protein 281

chr19_-_28057437 0.147 NM_001166414
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr2_-_125549883 0.143 NM_199022
Shc4
SHC (Src homology 2 domain containing) family, member 4
chr6_+_65902564 0.140 NM_001161773
4930544G11Rik
RIKEN cDNA 4930544G11 gene
chr13_-_23557675 0.136 NM_013483
Btn1a1
butyrophilin, subfamily 1, member A1
chr5_+_73882264 0.128 NM_001190733
NM_178896
Dcun1d4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr14_+_29831283 0.114 NM_176920
Lrtm1
leucine-rich repeats and transmembrane domains 1
chr1_+_107677241 0.107 NM_009399
Tnfrsf11a
tumor necrosis factor receptor superfamily, member 11a
chr1_-_24594228 0.103 NM_007733
Col19a1
collagen, type XIX, alpha 1
chr11_+_95275392 0.090 NM_025287
Spop
speckle-type POZ protein
chr1_+_168931547 0.089 NM_001160261
NM_001160262
NM_175461
Fam78b


family with sequence similarity 78, member B


chr17_+_45660382 0.086 NM_013688
Tcte1
t-complex-associated testis expressed 1
chr2_-_127410404 0.080 NM_001111029
NM_028141
Zfp661

zinc finger protein 661

chr6_-_97155541 0.076 NM_001111106
NM_011666
Uba3

ubiquitin-like modifier activating enzyme 3

chr17_+_15841889 0.068 NM_007690
Chd1
chromodomain helicase DNA binding protein 1
chr17_-_71824652 0.068 NM_028887
Smchd1
SMC hinge domain containing 1
chr10_+_84300892 0.068 NM_027689
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr18_+_53624169 0.067 NM_001033281
Prdm6
PR domain containing 6
chr19_-_40588297 0.066 NM_009166
Sorbs1
sorbin and SH3 domain containing 1
chr4_+_47366162 0.064 NM_009370
Tgfbr1
transforming growth factor, beta receptor I
chr11_-_30854081 0.063 NM_025745
Erlec1
endoplasmic reticulum lectin 1
chr8_-_129117310 0.062 NM_001164598
Irf2bp2
interferon regulatory factor 2 binding protein 2
chr7_+_112553081 0.061 NM_001033317
Cnga4
cyclic nucleotide gated channel alpha 4
chr9_+_110737091 0.056 NM_153172
Prss45
protease, serine, 45
chr5_+_124357243 0.054 NM_026603
Denr
density-regulated protein
chr9_-_37476762 0.048 NM_172454
Panx3
pannexin 3
chr6_-_134837738 0.035 NM_001167697
NM_001167699
NM_008157
Gpr19


G protein-coupled receptor 19


chr6_-_13557981 0.030 NM_028990
Tmem168
transmembrane protein 168
chr9_+_3532302 0.027 NM_001033322
Gucy1a2
guanylate cyclase 1, soluble, alpha 2
chr9_+_124036265 0.017 NM_009917
Ccr5
chemokine (C-C motif) receptor 5
chr4_+_151671441 0.009 NM_133788
Icmt
isoprenylcysteine carboxyl methyltransferase
chr5_-_144288812 0.008 NM_009007
Rac1
RAS-related C3 botulinum substrate 1
chr10_+_98569715 0.003 NM_027740
Poc1b
POC1 centriolar protein homolog B (Chlamydomonas)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.40 9.04e-04 GO:0010468 regulation of gene expression
2.84 1.07e-03 GO:0006351 transcription, DNA-dependent
2.84 1.11e-03 GO:0032774 RNA biosynthetic process
2.38 2.68e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.32 4.37e-03 GO:0010556 regulation of macromolecule biosynthetic process
2.27 4.51e-03 GO:0031326 regulation of cellular biosynthetic process
2.41 4.87e-03 GO:0006355 regulation of transcription, DNA-dependent
2.24 5.81e-03 GO:0009889 regulation of biosynthetic process
2.36 7.01e-03 GO:0051252 regulation of RNA metabolic process
2.06 7.67e-03 GO:0060255 regulation of macromolecule metabolic process
2.21 1.13e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.18 1.38e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.90 1.71e-02 GO:0019222 regulation of metabolic process
2.30 1.75e-02 GO:0016070 RNA metabolic process
2.24 2.70e-02 GO:0034645 cellular macromolecule biosynthetic process
2.18 3.08e-02 GO:0010467 gene expression
2.22 3.11e-02 GO:0009059 macromolecule biosynthetic process
1.92 4.67e-02 GO:0031323 regulation of cellular metabolic process

Nothing significant found in compartment category.

Nothing significant found in function category.