Motif ID: ACAGUAU

Z-value: 0.604


Mature miRNA associated with seed ACAGUAU:

NamemiRBase Accession
mmu-miR-144 MIMAT0000156



Activity profile for motif ACAGUAU.

activity profile for motif ACAGUAU


Sorted Z-values histogram for motif ACAGUAU

Sorted Z-values for motif ACAGUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_121558695 6.263 NM_011055
Pde3b
phosphodiesterase 3B, cGMP-inhibited
chr15_+_7090525 4.350 NM_013584
Lifr
leukemia inhibitory factor receptor
chr12_+_82127791 3.919 NM_001146217
NM_022316
Smoc1

SPARC related modular calcium binding 1

chr1_-_82287990 3.876 NM_010570
Irs1
insulin receptor substrate 1
chr15_+_68758773 3.562 NM_010158
Khdrbs3
KH domain containing, RNA binding, signal transduction associated 3
chr14_-_17407701 3.322 NM_011243
Rarb
retinoic acid receptor, beta
chr15_+_85566122 3.258 NM_011144
Ppara
peroxisome proliferator activated receptor alpha
chr3_+_52072251 3.141 NM_019739
Foxo1
forkhead box O1
chr15_+_85565935 3.031 NM_001113418
Ppara
peroxisome proliferator activated receptor alpha
chr1_-_166388431 2.946 NM_009721
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr13_-_115248924 2.944 NM_008046
Fst
follistatin
chr4_-_131631226 2.875 NM_001128607
Epb4.1
erythrocyte protein band 4.1
chr2_-_115890247 2.837 NM_001159569
NM_001159570
Meis2

Meis homeobox 2

chr8_-_105308910 2.759 NM_009866
Cdh11
cadherin 11
chr2_-_115890747 2.751 NM_001136072
NM_001159567
NM_001159568
NM_010825
Meis2



Meis homeobox 2



chr5_+_15440508 2.716 NM_001110843
NM_001110844
NM_001110845
NM_001110846
NM_009784
Cacna2d1




calcium channel, voltage-dependent, alpha2/delta subunit 1




chr4_-_131628011 2.673 NM_183428
Epb4.1
erythrocyte protein band 4.1
chr13_+_109444370 2.593 NM_011056
Pde4d
phosphodiesterase 4D, cAMP specific
chr4_+_132567420 2.551 NM_146155
Ahdc1
AT hook, DNA binding motif, containing 1
chr18_+_64500017 2.488 NM_194268
Onecut2
one cut domain, family member 2
chr1_-_31006599 2.327 NM_011200
Ptp4a1
protein tyrosine phosphatase 4a1
chr10_-_94879435 2.314 NM_007706
Socs2
suppressor of cytokine signaling 2
chr10_-_94878845 2.282 NM_001168655
Socs2
suppressor of cytokine signaling 2
chr15_+_10106992 2.281 NM_011169
Prlr
prolactin receptor
chr11_-_5344795 2.260 NM_001080924
Znrf3
zinc and ring finger 3
chr4_-_131604821 2.248 NM_001128606
Epb4.1
erythrocyte protein band 4.1
chr10_-_94877824 2.236 NM_001168657
Socs2
suppressor of cytokine signaling 2
chr10_-_94878117 2.215 NM_001168656
Socs2
suppressor of cytokine signaling 2
chr13_-_55671276 2.193 NM_001162881
Fam193b
family with sequence similarity 193, member B
chr19_-_37281762 2.189 NM_198300
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr14_+_34736772 2.179 NM_145741
Gdf10
growth differentiation factor 10
chr6_-_21802514 2.158 NM_173007
Tspan12
tetraspanin 12
chr18_+_35989376 2.151 NM_133687
Cxxc5
CXXC finger 5
chr16_-_11254052 2.123 NM_001130008
NM_146066
Gspt1

G1 to S phase transition 1

chr6_-_148894953 2.102 NM_019643
Fam60a
family with sequence similarity 60, member A
chr6_+_117118552 2.077 NM_001012477
NM_013655
NM_021704
Cxcl12


chemokine (C-X-C motif) ligand 12


chr15_+_80629020 1.989 NM_177124
Tnrc6b
trinucleotide repeat containing 6b
chr7_-_116760660 1.894 NM_001001326
NM_029811
St5

suppression of tumorigenicity 5

chr18_+_5591869 1.892 NM_011546
Zeb1
zinc finger E-box binding homeobox 1
chr9_-_14419410 1.889 NM_001081395
Amotl1
angiomotin-like 1
chr2_+_121692687 1.879 NM_177054
NM_199038
Casc4

cancer susceptibility candidate 4

chr3_+_82830071 1.871 NM_001111048
NM_010196
Fga

fibrinogen alpha chain

chr2_-_154900188 1.833 NM_016661
Ahcy
S-adenosylhomocysteine hydrolase
chr4_+_32504409 1.812 NM_001109661
Bach2
BTB and CNC homology 2
chr19_+_27291507 1.810 NM_001161420
NM_013703
Vldlr

very low density lipoprotein receptor

chr2_-_76820599 1.754 NM_011652
NM_028004
Ttn

titin

chr8_+_24521967 1.719 NM_013834
Sfrp1
secreted frizzled-related protein 1
chr18_-_23197156 1.694 NM_001161483
Nol4
nucleolar protein 4
chr10_+_85763156 1.691 NM_011595
Timp3
tissue inhibitor of metalloproteinase 3
chr11_+_72420705 1.684 NM_025985
Ube2g1
ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)
chr10_-_62342761 1.620 NM_027384
Tet1
tet oncogene 1
chr14_+_20570444 1.606 NM_008695
Nid2
nidogen 2
chr1_-_160887568 1.605 NM_001085376
Pappa2
pappalysin 2
chr8_-_124175827 1.564 NM_080855
Zcchc14
zinc finger, CCHC domain containing 14
chr15_+_80541675 1.558 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr9_+_32503600 1.552 NM_001038642
NM_011808
Ets1

E26 avian leukemia oncogene 1, 5' domain

chr2_+_158492468 1.545 NM_153089
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr4_+_137418151 1.536 NM_199307
Ece1
endothelin converting enzyme 1
chr16_+_33380860 1.527 NM_011749
Zfp148
zinc finger protein 148
chr8_-_49760037 1.465 NM_001145937
NM_011857
Odz3

odd Oz/ten-m homolog 3 (Drosophila)

chr13_-_55672471 1.439 NM_145382
Fam193b
family with sequence similarity 193, member B
chr6_+_88148657 1.433 NM_008090
Gata2
GATA binding protein 2
chr1_-_72921438 1.407 NM_010518
Igfbp5
insulin-like growth factor binding protein 5
chr4_+_133871031 1.405 NM_001039048
Trim63
tripartite motif-containing 63
chr8_-_38001686 1.338 NM_001194940
Dlc1
deleted in liver cancer 1
chr15_+_38837839 1.293 NM_008056
Fzd6
frizzled homolog 6 (Drosophila)
chr8_+_12915892 1.286 NM_178076
Mcf2l
mcf.2 transforming sequence-like
chr8_+_12949417 1.281 NM_001159485
NM_001159486
Mcf2l

mcf.2 transforming sequence-like

chr15_+_38837818 1.273 NM_001162494
Fzd6
frizzled homolog 6 (Drosophila)
chr2_+_109757803 1.264 NM_172671
Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
chr8_+_106625524 1.256 NM_009868
Cdh5
cadherin 5
chr8_-_91568060 1.254 NM_021390
Sall1
sal-like 1 (Drosophila)
chr10_+_110943341 1.237 NM_009344
Phlda1
pleckstrin homology-like domain, family A, member 1
chr17_+_26551909 1.231 NM_001081656
Neurl1b
neuralized homolog 1b (Drosophila)
chr6_+_38383918 1.230 NM_177185
Ubn2
ubinuclein 2
chr9_-_94438499 1.225 NM_001033145
1190002N15Rik
RIKEN cDNA 1190002N15 gene
chr18_+_58038278 1.166 NM_009194
Slc12a2
solute carrier family 12, member 2
chr4_-_53172748 1.147 NM_013454
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr18_+_10325174 1.130 NM_001083628
Greb1l
growth regulation by estrogen in breast cancer-like
chr18_+_69505374 1.117 NM_001083967
Tcf4
transcription factor 4
chr2_+_181531011 1.099 NM_001171680
Myt1
myelin transcription factor 1
chr8_-_37796104 1.097 NM_001194941
Dlc1
deleted in liver cancer 1
chr15_+_99223377 1.091 NM_001171034
NM_001171036
NM_026669
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr3_+_31801595 1.080 NM_028231
Kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr6_-_52184909 1.075 NM_008263
Hoxa10
homeobox A10
chr19_-_47538898 1.062 NM_001164717
NM_008018
Sh3pxd2a

SH3 and PX domains 2A

chr9_-_30729990 1.051 NM_001024139
Adamts15
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr7_+_37483093 1.043 NM_172298
Tshz3
teashirt zinc finger family member 3
chr8_+_109674517 1.035 NM_025558
Cyb5b
cytochrome b5 type B
chr10_+_61143056 1.011 NM_009120
Sar1a
SAR1 gene homolog A (S. cerevisiae)
chr7_-_123182257 1.004 NM_001025559
Sox6
SRY-box containing gene 6
chr4_+_97248556 0.992 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr8_+_23587151 0.991 NM_011394
Slc20a2
solute carrier family 20, member 2
chr1_+_189821727 0.989 NM_011935
Esrrg
estrogen-related receptor gamma
chr16_+_11066390 0.986 NM_009223
Snn
stannin
chrX_+_80194208 0.968 NM_007868
Dmd
dystrophin, muscular dystrophy
chr2_+_158492854 0.945 NM_001159662
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr2_-_12223518 0.941 NM_001001309
Itga8
integrin alpha 8
chr2_-_156904966 0.933 NM_001164663
9830001H06Rik
RIKEN cDNA 9830001H06 gene
chr2_-_37278415 0.932 NM_001100591
Rc3h2
ring finger and CCCH-type zinc finger domains 2
chr4_+_97444312 0.929 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr3_+_5218545 0.923 NM_030708
Zfhx4
zinc finger homeodomain 4
chr5_-_38215607 0.922 NM_010835
Msx1
homeobox, msh-like 1
chr5_+_144861227 0.921 NM_001081109
Lmtk2
lemur tyrosine kinase 2
chr3_-_126646303 0.898 NM_001034168
Ank2
ankyrin 2, brain
chr10_+_43198945 0.885 NM_199028
Bend3
BEN domain containing 3
chr7_-_123138599 0.880 NM_011445
Sox6
SRY-box containing gene 6
chr19_-_34952377 0.877 NM_023792
Pank1
pantothenate kinase 1
chr5_+_67137054 0.875 NM_001001980
Limch1
LIM and calponin homology domains 1
chr2_+_155207581 0.857 NM_178111
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr4_-_82151180 0.853 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr18_-_58369579 0.850 NM_010181
Fbn2
fibrillin 2
chr5_+_89316245 0.843 NM_001136260
NM_001197147
NM_018760
Slc4a4


solute carrier family 4 (anion exchanger), member 4


chr7_-_88599560 0.813 NM_007755
Cpeb1
cytoplasmic polyadenylation element binding protein 1
chr11_-_61393108 0.807 NM_010148
Epn2
epsin 2
chr10_+_77068939 0.805 NM_019929
Sumo3
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr17_+_31701700 0.803 NM_016670
Pknox1
Pbx/knotted 1 homeobox
chr19_-_19075535 0.801 NM_146095
Rorb
RAR-related orphan receptor beta
chr11_+_80196766 0.791 NM_001130169
NM_001130170
NM_001130171
NM_011751
Zfp207



zinc finger protein 207



chr11_-_118947424 0.784 NM_007625
Cbx4
chromobox homolog 4 (Drosophila Pc class)
chr16_-_13668230 0.782 NM_028761
Parn
poly(A)-specific ribonuclease (deadenylation nuclease)
chr4_+_11083585 0.782 NM_021897
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr7_-_123174560 0.781 NM_001025560
Sox6
SRY-box containing gene 6
chr4_+_54960816 0.779 NM_172867
Zfp462
zinc finger protein 462
chr13_-_46060325 0.776 NM_009124
Atxn1
ataxin 1
chr18_+_69504145 0.772 NM_013685
Tcf4
transcription factor 4
chr4_+_130219255 0.771 NM_001159603
NM_001159604
NM_001159605
NM_001159606
NM_030722
Pum1




pumilio 1 (Drosophila)




chr11_+_53164267 0.758 NM_033565
Aff4
AF4/FMR2 family, member 4
chr15_+_99223622 0.755 NM_001171035
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr19_+_3851772 0.748 NM_001025566
NM_013490
Chka

choline kinase alpha

chr7_-_87260156 0.740 NM_173011
Idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr8_-_37676995 0.733 NM_015802
Dlc1
deleted in liver cancer 1
chr4_-_128483355 0.729 NM_001081098
Zfp362
zinc finger protein 362
chr14_+_22319075 0.720 NM_017479
Myst4
MYST histone acetyltransferase monocytic leukemia 4
chrX_+_135448968 0.718 NM_013724
Nrk
Nik related kinase
chr2_+_69735301 0.708 NM_001081548
NM_177783
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr12_-_52792851 0.708 NM_001172098
NM_052973
Strn3

striatin, calmodulin binding protein 3

chr5_-_115608153 0.692 NM_175403
Mlec
malectin
chr17_+_86567003 0.688 NM_011104
Prkce
protein kinase C, epsilon
chr10_-_42894259 0.687 NM_175407
Sobp
sine oculis-binding protein homolog (Drosophila)
chr14_+_19103655 0.682 NM_023526
Nkiras1
NFKB inhibitor interacting Ras-like protein 1
chr4_-_154010868 0.678 NM_001177995
NM_027504
Prdm16

PR domain containing 16

chr5_-_36022428 0.664 NM_001042615
NM_030127
Htra3

HtrA serine peptidase 3

chr6_-_148779856 0.662 NM_001081113
Ipo8
importin 8
chr13_-_54789548 0.661 NM_001146027
Rnf44
ring finger protein 44
chr2_+_4802609 0.659 NM_175400
Sephs1
selenophosphate synthetase 1
chr3_-_113332817 0.653 NM_001038696
NM_026043
Rnpc3

RNA-binding region (RNP1, RRM) containing 3

chr2_-_102241053 0.643 NM_020267
Trim44
tripartite motif-containing 44
chr5_-_37087204 0.641 NM_001081232
D5Ertd579e
DNA segment, Chr 5, ERATO Doi 579, expressed
chr7_-_73572306 0.641 NM_053080
Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr11_-_69419419 0.626 NM_013415
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr5_+_36235967 0.625 NM_027373
Afap1
actin filament associated protein 1
chr7_-_118226515 0.623 NM_001040131
NM_013507
Eif4g2

eukaryotic translation initiation factor 4, gamma 2

chr2_-_58177217 0.616 NM_001033369
Acvr1c
activin A receptor, type IC
chr2_+_156665812 0.613 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr11_-_18918923 0.609 NM_001193271
NM_010789
Meis1

Meis homeobox 1

chr13_+_55311142 0.604 NM_008739
Nsd1
nuclear receptor-binding SET-domain protein 1
chr13_-_54789148 0.598 NM_001146025
NM_001146026
NM_134064
Rnf44


ring finger protein 44


chr2_-_9800211 0.597 NM_008091
Gata3
GATA binding protein 3
chr3_+_133903056 0.594 NM_001004367
Cxxc4
CXXC finger 4
chrX_+_132804791 0.593 NM_001110233
NM_001110234
NM_009750
Ngfrap1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr10_+_56097078 0.591 NM_010288
Gja1
gap junction protein, alpha 1
chr12_-_12948513 0.583 NM_008709
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr3_-_9610062 0.582 NM_133218
Zfp704
zinc finger protein 704
chr19_-_34953810 0.578 NM_001114339
Pank1
pantothenate kinase 1
chr9_+_21001148 0.572 NM_019798
Pde4a
phosphodiesterase 4A, cAMP specific
chr2_+_103252254 0.571 NM_001145813
Elf5
E74-like factor 5
chr12_+_16901671 0.571 NM_009072
Rock2
Rho-associated coiled-coil containing protein kinase 2
chr19_+_32832002 0.569 NM_008960
Pten
phosphatase and tensin homolog
chr2_-_38640034 0.567 NM_001159548
NM_001159549
Nr6a1

nuclear receptor subfamily 6, group A, member 1

chrX_+_97170927 0.560 NM_001177937
NM_001177938
NM_001177939
NM_001177940
NM_001177941
NM_001177942
NM_001177943
NM_001177944
NM_010099
Eda








ectodysplasin-A








chr13_-_64376186 0.558 NM_172587
Cdc14b
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr15_+_66409094 0.552 NM_001081409
Phf20l1
PHD finger protein 20-like 1
chr1_-_58642994 0.552 NM_172513
Fam126b
family with sequence similarity 126, member B
chr9_+_77602582 0.549 NM_010295
Gclc
glutamate-cysteine ligase, catalytic subunit
chr2_-_58210162 0.546 NM_001111030
Acvr1c
activin A receptor, type IC
chr6_+_107479719 0.540 NM_008516
Lrrn1
leucine rich repeat protein 1, neuronal
chr1_+_193149772 0.536 NM_025864
Tmem206
transmembrane protein 206
chr2_+_181498036 0.527 NM_001171615
Myt1
myelin transcription factor 1
chr6_+_112409498 0.525 NM_007617
Cav3
caveolin 3
chr15_+_96117952 0.520 NM_175251
Arid2
AT rich interactive domain 2 (ARID, RFX-like)
chr17_-_63230665 0.519 NM_010109
NM_207654
Efna5

ephrin A5

chr3_-_126701367 0.517 NM_178655
Ank2
ankyrin 2, brain
chr9_-_114473486 0.514 NM_001042503
Trim71
tripartite motif-containing 71
chr5_+_143105467 0.513 NM_178398
Wipi2
WD repeat domain, phosphoinositide interacting 2
chr16_+_70314331 0.510 NM_028803
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr2_-_24775083 0.510 NM_001012518
NM_001109686
NM_001109687
NM_172545
Ehmt1



euchromatic histone methyltransferase 1



chr3_+_88769733 0.505 NM_138679
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr3_+_135101664 0.504 NM_025356
Ube2d3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr5_+_73872293 0.503 NM_001190734
Dcun1d4
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr13_+_55794441 0.498 NM_181278
B230219D22Rik
RIKEN cDNA B230219D22 gene
chr13_+_48356795 0.496 NM_031166
Id4
inhibitor of DNA binding 4
chr2_-_104334610 0.484 NM_001145824
NM_010434
Hipk3

homeodomain interacting protein kinase 3

chr14_+_73952438 0.484 NM_011506
Sucla2
succinate-Coenzyme A ligase, ADP-forming, beta subunit
chr9_+_20970150 0.483 NM_183408
Pde4a
phosphodiesterase 4A, cAMP specific
chr4_-_133309484 0.478 NM_001080819
Arid1a
AT rich interactive domain 1A (SWI-like)
chr5_-_20387886 0.478 NM_172992
Phtf2
putative homeodomain transcription factor 2
chr7_-_77505248 0.457 NM_009697
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr19_-_41338400 0.455 NM_133352
Tm9sf3
transmembrane 9 superfamily member 3
chr14_-_25065141 0.454 NM_001163513
NM_027726
Dlg5

discs, large homolog 5 (Drosophila)


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.41 1.43e-20 GO:0080090 regulation of primary metabolic process
2.44 2.62e-20 GO:0060255 regulation of macromolecule metabolic process
2.34 1.05e-18 GO:0031323 regulation of cellular metabolic process
2.57 3.25e-17 GO:0010468 regulation of gene expression
2.17 5.72e-17 GO:0019222 regulation of metabolic process
2.53 2.93e-15 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.47 1.55e-14 GO:0010556 regulation of macromolecule biosynthetic process
2.56 1.56e-14 GO:0051252 regulation of RNA metabolic process
2.36 2.03e-13 GO:0031326 regulation of cellular biosynthetic process
2.33 4.65e-13 GO:0009889 regulation of biosynthetic process
2.33 1.21e-12 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.47 1.57e-12 GO:0006355 regulation of transcription, DNA-dependent
2.30 2.34e-12 GO:0051171 regulation of nitrogen compound metabolic process
2.09 1.12e-10 GO:0032502 developmental process
2.14 2.23e-10 GO:0007275 multicellular organismal development
2.26 3.29e-10 GO:0048522 positive regulation of cellular process
1.54 5.30e-10 GO:0050794 regulation of cellular process
1.78 3.71e-09 GO:0044260 cellular macromolecule metabolic process
2.50 4.41e-09 GO:0006351 transcription, DNA-dependent
2.50 4.78e-09 GO:0032774 RNA biosynthetic process
2.11 5.45e-09 GO:0048518 positive regulation of biological process
2.13 5.91e-09 GO:0048856 anatomical structure development
1.47 1.14e-08 GO:0065007 biological regulation
3.11 1.64e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.18 1.89e-08 GO:0048731 system development
2.44 1.99e-08 GO:0048513 organ development
2.09 2.10e-08 GO:0090304 nucleic acid metabolic process
1.70 2.18e-08 GO:0043170 macromolecule metabolic process
1.48 2.59e-08 GO:0050789 regulation of biological process
2.18 3.77e-08 GO:0016070 RNA metabolic process
1.95 6.08e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.10 7.32e-08 GO:0010467 gene expression
2.58 9.04e-08 GO:0023051 regulation of signaling
2.62 1.18e-07 GO:0009653 anatomical structure morphogenesis
3.29 1.49e-07 GO:0051254 positive regulation of RNA metabolic process
3.20 1.84e-07 GO:0009790 embryo development
1.57 1.95e-07 GO:0044237 cellular metabolic process
3.25 3.68e-07 GO:0045893 positive regulation of transcription, DNA-dependent
3.04 4.84e-07 GO:0009888 tissue development
2.60 5.90e-07 GO:0010604 positive regulation of macromolecule metabolic process
1.81 9.30e-07 GO:0006807 nitrogen compound metabolic process
2.66 1.02e-06 GO:0009966 regulation of signal transduction
3.06 1.11e-06 GO:0010628 positive regulation of gene expression
1.82 1.12e-06 GO:0034641 cellular nitrogen compound metabolic process
2.49 1.12e-06 GO:0009893 positive regulation of metabolic process
2.99 1.33e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.94 1.99e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
2.63 2.15e-06 GO:0007399 nervous system development
2.91 2.68e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
2.50 3.28e-06 GO:0031325 positive regulation of cellular metabolic process
3.48 4.22e-06 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.81 4.61e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.50 7.94e-06 GO:0044238 primary metabolic process
2.76 8.03e-06 GO:0009891 positive regulation of biosynthetic process
1.45 8.17e-06 GO:0008152 metabolic process
1.99 1.15e-05 GO:0034645 cellular macromolecule biosynthetic process
1.97 1.62e-05 GO:0009059 macromolecule biosynthetic process
2.58 3.23e-05 GO:0009892 negative regulation of metabolic process
3.04 5.26e-05 GO:0010629 negative regulation of gene expression
2.06 5.80e-05 GO:0030154 cell differentiation
2.98 7.95e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.60 9.02e-05 GO:0031324 negative regulation of cellular metabolic process
2.52 9.44e-05 GO:0010646 regulation of cell communication
1.25 9.49e-05 GO:0009987 cellular process
3.10 9.89e-05 GO:0009887 organ morphogenesis
2.59 1.01e-04 GO:0010605 negative regulation of macromolecule metabolic process
6.59 1.14e-04 GO:0048736 appendage development
6.59 1.14e-04 GO:0060173 limb development
1.77 1.40e-04 GO:0044249 cellular biosynthetic process
2.00 1.66e-04 GO:0048869 cellular developmental process
2.87 1.94e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
3.56 2.06e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
3.05 2.34e-04 GO:0045892 negative regulation of transcription, DNA-dependent
3.00 3.20e-04 GO:0051253 negative regulation of RNA metabolic process
2.77 3.98e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.72 4.90e-04 GO:0009058 biosynthetic process
2.11 5.18e-04 GO:0048583 regulation of response to stimulus
3.60 5.95e-04 GO:0009968 negative regulation of signal transduction
6.29 6.02e-04 GO:0035107 appendage morphogenesis
6.29 6.02e-04 GO:0035108 limb morphogenesis
2.71 6.63e-04 GO:0009890 negative regulation of biosynthetic process
1.91 6.65e-04 GO:0048523 negative regulation of cellular process
3.45 6.65e-04 GO:0010648 negative regulation of cell communication
3.64 9.23e-04 GO:0007167 enzyme linked receptor protein signaling pathway
3.14 1.07e-03 GO:0009792 embryo development ending in birth or egg hatching
3.34 1.13e-03 GO:0048598 embryonic morphogenesis
3.28 1.49e-03 GO:0007417 central nervous system development
2.36 1.50e-03 GO:0051246 regulation of protein metabolic process
2.73 2.10e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.40 2.31e-03 GO:0030900 forebrain development
3.30 2.45e-03 GO:0023057 negative regulation of signaling
1.49 2.52e-03 GO:0032501 multicellular organismal process
2.69 2.82e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
3.05 2.93e-03 GO:0043009 chordate embryonic development
3.05 2.93e-03 GO:0048585 negative regulation of response to stimulus
1.80 3.21e-03 GO:0048519 negative regulation of biological process
2.38 3.52e-03 GO:0032268 regulation of cellular protein metabolic process
4.23 3.83e-03 GO:0043193 positive regulation of gene-specific transcription
3.56 4.70e-03 GO:0035295 tube development
2.95 5.07e-03 GO:0072358 cardiovascular system development
2.95 5.07e-03 GO:0072359 circulatory system development
2.91 6.39e-03 GO:0048646 anatomical structure formation involved in morphogenesis
3.46 6.90e-03 GO:0007420 brain development
3.38 9.60e-03 GO:0007423 sensory organ development
4.07 1.25e-02 GO:0048732 gland development
2.38 1.40e-02 GO:0048468 cell development
3.07 2.03e-02 GO:0032583 regulation of gene-specific transcription
3.07 2.11e-02 GO:0060429 epithelium development
5.49 4.96e-02 GO:0030326 embryonic limb morphogenesis
5.49 4.96e-02 GO:0035113 embryonic appendage morphogenesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.88 6.79e-14 GO:0005634 nucleus
1.34 1.39e-08 GO:0005622 intracellular
1.34 5.41e-08 GO:0044424 intracellular part
1.44 1.02e-07 GO:0043231 intracellular membrane-bounded organelle
1.43 1.23e-07 GO:0043227 membrane-bounded organelle
1.32 5.43e-05 GO:0043229 intracellular organelle
1.32 6.85e-05 GO:0043226 organelle
1.14 3.57e-03 GO:0005623 cell
1.14 3.57e-03 GO:0044464 cell part
1.84 4.75e-03 GO:0044428 nuclear part
1.64 4.81e-03 GO:0043234 protein complex
1.56 6.84e-03 GO:0032991 macromolecular complex
1.88 1.41e-02 GO:0031981 nuclear lumen
2.34 2.20e-02 GO:0044451 nucleoplasm part
2.04 2.89e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.52 4.68e-20 GO:0005488 binding
2.47 2.43e-15 GO:0003676 nucleic acid binding
1.72 3.43e-11 GO:0005515 protein binding
3.64 1.19e-10 GO:0001071 nucleic acid binding transcription factor activity
3.64 1.19e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
2.51 4.00e-10 GO:0003677 DNA binding
2.72 1.62e-09 GO:0008270 zinc ion binding
1.92 6.26e-09 GO:0043169 cation binding
1.91 7.76e-09 GO:0043167 ion binding
3.11 1.11e-08 GO:0030528 transcription regulator activity
1.90 1.82e-08 GO:0046872 metal ion binding
3.51 3.46e-08 GO:0043565 sequence-specific DNA binding
2.35 1.99e-07 GO:0046914 transition metal ion binding
4.23 4.24e-06 GO:0016563 transcription activator activity
3.85 1.76e-04 GO:0016564 transcription repressor activity
3.69 6.27e-04 GO:0008134 transcription factor binding
2.72 6.91e-03 GO:0019904 protein domain specific binding
21.12 7.77e-03 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.73 8.39e-03 GO:0000166 nucleotide binding
2.31 2.77e-02 GO:0003723 RNA binding
7.61 3.70e-02 GO:0003707 steroid hormone receptor activity
7.46 4.14e-02 GO:0004879 ligand-dependent nuclear receptor activity