Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 1.583


Transcription factors associated with ADNP_IRX_SIX_ZHX.p2:

Gene SymbolEntrez IDGene Name
Adnp 11538 activity-dependent neuroprotective protein
Irx4 50916 Iroquois related homeobox 4 (Drosophila)
Irx5 54352 Iroquois related homeobox 5 (Drosophila)
Six2 20472 sine oculis-related homeobox 2 homolog (Drosophila)
Six5 20475 sine oculis-related homeobox 5 homolog (Drosophila)
Zhx1 22770 zinc fingers and homeoboxes 1
Zhx2 387609 zinc fingers and homeoboxes 2
Zhx3 320799 zinc fingers and homeoboxes 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zhx1chr15_-_57907735-0.199.1e-03Click!
Adnpchr2_-_168032561-0.138.2e-02Click!
Six2chr17_-_860875860.121.2e-01Click!
Six5chr7_+_19679892,
chr7_+_19680105
0.111.3e-01Click!
Irx4chr13_+_73397944-0.063.8e-01Click!
Zhx2chr15_+_575262120.054.8e-01Click!
Zhx3chr2_-_160698705-0.027.4e-01Click!
Irx5chr8_+_94881694,
chr8_+_94881868
-0.019.0e-01Click!


Activity profile for motif ADNP_IRX_SIX_ZHX.p2.

activity profile for motif ADNP_IRX_SIX_ZHX.p2


Sorted Z-values histogram for motif ADNP_IRX_SIX_ZHX.p2

Sorted Z-values for motif ADNP_IRX_SIX_ZHX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ADNP_IRX_SIX_ZHX.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_54839147 28.941 Znrf2
zinc and ring finger 2
chr4_+_116265582 23.105 Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr6_-_51413182 21.811 Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr1_+_89951985 21.365 NM_201641
Ugt1a10
UDP glycosyltransferase 1 family, polypeptide A10
chr10_-_117252126 20.140


chr1_-_30920095 18.730 NM_001081080
Phf3
PHD finger protein 3
chr1_+_6720087 17.973 NM_173868
St18
suppression of tumorigenicity 18
chr1_+_6720153 17.825 St18
suppression of tumorigenicity 18
chr7_-_80686630 17.675 NM_001081345
Chd2
chromodomain helicase DNA binding protein 2
chr4_+_98697606 17.510 NM_013913
Angptl3
angiopoietin-like 3
chr5_-_66000506 17.095 B230308N11Rik
RIKEN cDNA B230308N11 gene
chr6_-_68967061 17.070


chr7_+_138712015 14.664 Bub3
budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
chr6_+_134874663 13.835 Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr4_+_132753616 13.440


chrX_-_159402493 12.252 NM_009789
S100g
S100 calcium binding protein G
chr1_+_45402907 12.143 Col3a1
collagen, type III, alpha 1
chr13_-_29045399 12.068 NM_009238
Sox4
SRY-box containing gene 4
chr5_-_87997908 11.920 Sult1d1
sulfotransferase family 1D, member 1
chr1_-_167865030 11.908 NM_198933
NM_198934
Pou2f1

POU domain, class 2, transcription factor 1

chr9_+_7792286 11.862 Tmem123
transmembrane protein 123
chr2_-_37225800 11.809 Rc3h2
ring finger and CCCH-type zinc finger domains 2
chr1_+_89967340 11.750 NM_201644
Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr17_+_35404109 11.502


chr3_+_59885782 11.394 NM_032400
Sucnr1
succinate receptor 1
chr11_-_77707282 11.384 NM_008952
Pipox
pipecolic acid oxidase
chr16_+_34995000 10.946 Mylk
myosin, light polypeptide kinase
chr8_+_91115856 10.941 Nkd1
naked cuticle 1 homolog (Drosophila)
chr5_-_52541869 10.762 Dhx15
DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr8_+_120225866 10.704 Hsd17b2
hydroxysteroid (17-beta) dehydrogenase 2
chr8_+_91116225 10.388 Nkd1
naked cuticle 1 homolog (Drosophila)
chr12_-_76815494 10.385


chr17_+_35403998 10.225


chr5_-_88956788 10.223 NM_152839
Igj
immunoglobulin joining chain
chrM_-_13886 9.985


chr13_+_9171776 9.963 Larp4b
La ribonucleoprotein domain family, member 4B
chr6_+_83290548 9.739 Mobkl1b
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr1_-_140071818 9.722 NM_001111316
NM_011210
Ptprc

protein tyrosine phosphatase, receptor type, C

chr1_+_90062617 9.685 Ugt1a5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr1_+_90062550 9.653 NM_201643
Ugt1a5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr5_-_87569342 9.378 NM_009467
Ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr15_+_58731646 9.373 Rnf139
ring finger protein 139
chr2_-_72931338 9.131


chrX_-_159402465 9.016 S100g
S100 calcium binding protein G
chr16_+_34994935 8.949 Mylk
myosin, light polypeptide kinase
chr6_-_52176102 8.781 Hoxa9
homeobox A9
chr1_+_90003410 8.649 Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr10_+_101621491 8.575 NM_001162368
Mgat4c
4930402I19Rik
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
RIKEN cDNA 4930402I19 gene
chr3_+_59885811 8.560 Sucnr1
succinate receptor 1
chr3_+_5090275 8.559


chr13_-_104554635 8.533 NM_172592
Srsf12
serine/arginine-rich splicing factor 12
chr4_-_49562400 8.525 Aldob
aldolase B, fructose-bisphosphate
chr5_-_87853212 8.477 NM_133894
Ugt2b38
UDP glucuronosyltransferase 2 family, polypeptide B38
chr11_+_51085400 8.457 Clk4
CDC like kinase 4
chr8_-_5105158 8.438 NM_011388
Slc10a2
solute carrier family 10, member 2
chr16_-_97985323 8.412 NM_023663
Ripk4
receptor-interacting serine-threonine kinase 4
chr5_-_100391613 8.386 Hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr6_+_129543505 8.291 NM_010654
Klrd1
killer cell lectin-like receptor, subfamily D, member 1
chr15_+_31154176 8.256 Dap
death-associated protein
chr8_-_64601861 8.242 NM_001136089
NM_011922
Anxa10

annexin A10

chr14_+_27813547 8.239 NM_010420
Hesx1
homeobox gene expressed in ES cells
chr2_+_132673469 8.226 NM_025646
Crls1
cardiolipin synthase 1
chr10_+_101621712 8.175 NM_001162369
Mgat4c
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_-_52154325 8.170 Hoxa5
homeobox A5
chr6_+_83293435 8.120 Mobkl1b
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr1_+_19202046 8.117 NM_001025305
Tcfap2b
transcription factor AP-2 beta
chr15_-_96861590 8.104 Slc38a4
solute carrier family 38, member 4
chr9_+_108239210 8.076 Rhoa
ras homolog gene family, member A
chr6_-_3444484 8.032 NM_178899
Hepacam2
HEPACAM family member 2
chr5_-_87998014 8.029 NM_016771
Sult1d1
sulfotransferase family 1D, member 1
chr5_-_66410130 7.950 Rbm47
RNA binding motif protein 47
chr15_+_31154137 7.913 NM_146057
Dap
death-associated protein
chr1_-_127289729 7.844


chr17_-_79384763 7.786 Prkd3
protein kinase D3
chr5_-_89886732 7.751 NM_008096
Gc
group specific component
chr11_+_79845841 7.550 Suz12
suppressor of zeste 12 homolog (Drosophila)
chr6_-_69494873 7.528 Igkv4-57-1
immunoglobulin kappa variable 4-57-1
chr3_-_131047840 7.358 NM_028943
Sgms2
sphingomyelin synthase 2
chr3_+_121160714 7.303 Cnn3
calponin 3, acidic
chr3_+_137949734 7.264 Adh1
alcohol dehydrogenase 1 (class I)
chr15_+_31154178 7.249 Dap
death-associated protein
chr5_+_90889913 7.191 NM_009654
Alb
albumin
chr7_-_91763744 7.137 Zfand6
zinc finger, AN1-type domain 6
chr9_-_85637765 7.098 NM_001081282
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr6_-_69367406 7.083 Igkv4-68
immunoglobulin kappa variable 4-68
chr14_+_119380708 7.074


chr9_-_21935019 7.051 NM_007388
Acp5
acid phosphatase 5, tartrate resistant
chr11_+_87895626 7.001 Vezf1
vascular endothelial zinc finger 1
chr15_-_79363346 6.998 NM_152806
Ddx17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr9_-_44611055 6.966 Ttc36
tetratricopeptide repeat domain 36
chr3_+_135128934 6.927 Ube2d3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr2_+_74560034 6.880 NM_010469
Hoxd4
homeobox D4
chr7_+_77509969 6.872 B130024G19Rik
RIKEN cDNA B130024G19 gene
chr14_+_79601537 6.842


chr1_-_140071630 6.825 Ptprc
protein tyrosine phosphatase, receptor type, C
chr2_-_84490827 6.736 NM_001085448
NM_001085449
NM_001085450
NM_007615
Ctnnd1



catenin (cadherin associated protein), delta 1



chr17_-_44951745 6.731 NM_001146038
NM_009820
Runx2

runt related transcription factor 2

chr6_-_129422702 6.712 NM_020008
Clec7a
C-type lectin domain family 7, member a
chrX_+_156146532 6.693 NM_021389
Sh3kbp1
SH3-domain kinase binding protein 1
chr2_-_84490666 6.680 NM_001085453
Ctnnd1
catenin (cadherin associated protein), delta 1
chr6_-_87793898 6.585 Cnbp
cellular nucleic acid binding protein
chr12_-_77896363 6.576 Gpx2
glutathione peroxidase 2
chr2_+_112307393 6.569 2900064A13Rik
RIKEN cDNA 2900064A13 gene
chr12_-_77896410 6.546 Gpx2
glutathione peroxidase 2
chr2_+_87366184 6.531 Srp9
signal recognition particle 9
chr10_-_60561786 6.515


chr10_-_60561763 6.479


chr7_-_91827857 6.462 NM_022985
Zfand6
zinc finger, AN1-type domain 6
chr2_-_62321694 6.418 NM_008100
Gcg
glucagon
chr16_-_15966921 6.400 2310008H04Rik
RIKEN cDNA 2310008H04 gene
chr1_+_90034940 6.379 Ugt1a6a
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr1_-_55135054 6.347 Hspd1
heat shock protein 1 (chaperonin)
chrX_+_12870471 6.333 Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr7_+_35905996 6.324 Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr2_+_103252254 6.321 NM_001145813
Elf5
E74-like factor 5
chr5_+_88095232 6.309 NM_007784
Csn1s1
casein alpha s1
chr1_-_128727208 6.304 NM_001081756
NM_176957
Nckap5

NCK-associated protein 5

chr12_-_77896481 6.237 Gpx2
glutathione peroxidase 2
chr18_+_60963495 6.144 NM_001042605
NM_010545
Cd74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

chr12_-_77896534 6.133 NM_030677
Gpx2
glutathione peroxidase 2
chr2_-_30816439 6.058


chr1_-_130224894 6.044 NM_001081078
Lct
lactase
chr11_+_101229029 6.011 NM_008061
G6pc
glucose-6-phosphatase, catalytic
chr5_+_90889937 6.007 Alb
albumin
chr9_+_44206258 5.980 NM_008063
Slc37a4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr13_+_74543843 5.976 Gm15590
ferritin light chain 1 pseudogene
chr13_-_58494637 5.948 Hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr11_-_99299443 5.945 NM_023256
Krt20
keratin 20
chr5_+_90919739 5.873 NM_007423
Afp
alpha fetoprotein
chr15_+_102864825 5.843 NM_013553
Hoxc4
homeobox C4
chr9_-_44611033 5.828 NM_138951
Ttc36
tetratricopeptide repeat domain 36
chr6_+_83293025 5.821 Mobkl1b
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr6_-_136890189 5.776 NM_007486
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr18_-_32297813 5.750 NM_001042768
NM_008934
Proc

protein C

chr5_-_109104587 5.745 NM_174870
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr18_-_39572137 5.718 Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr6_-_87793459 5.632 Cnbp
cellular nucleic acid binding protein
chr17_+_8428907 5.624 NM_001190333
Ccr6
chemokine (C-C motif) receptor 6
chr2_-_103143314 5.610 Ehf
ets homologous factor
chr9_-_44610921 5.600 Ttc36
tetratricopeptide repeat domain 36
chrX_-_133268136 5.573 Morf4l2
mortality factor 4 like 2
chr16_+_20692792 5.570


chr17_-_6132461 5.486 Gm15590
ferritin light chain 1 pseudogene
chr1_-_172018982 5.485 NM_022563
Ddr2
discoidin domain receptor family, member 2
chr8_-_63433528 5.470 NM_173876
Clcn3
chloride channel 3
chr17_-_57367542 5.458 NM_009778
C3
complement component 3
chr2_+_162760505 5.446


chr16_-_11137100 5.441 Zc3h7a
zinc finger CCCH type containing 7 A
chr4_+_128688217 5.421


chr13_+_49639799 5.397 NM_001172481
NM_025711
Aspn

asporin

chr19_+_58586482 5.386 NM_029372
1700011F14Rik
RIKEN cDNA 1700011F14 gene
chr10_+_92951804 5.362 Hal
histidine ammonia lyase
chr3_+_19869841 5.339 Cp
ceruloplasmin
chr5_+_88354611 5.338 NM_007786
Csn3
casein kappa
chr9_+_61220162 5.331 NM_001083927
NM_001083928
NM_009389
Tle3


transducin-like enhancer of split 3, homolog of Drosophila E(spl)


chr2_-_27118325 5.319 Vav2
vav 2 oncogene
chr14_-_34195326 5.311 Mapk8
mitogen-activated protein kinase 8
chr7_+_36234110 5.287 NM_001199015
NM_001199016
NM_021291
Slc7a9


solute carrier family 7 (cationic amino acid transporter, y+ system), member 9


chr1_+_19198994 5.272 NM_009334
Tcfap2b
transcription factor AP-2 beta
chr6_+_70648433 5.272 Igkv3-2
immunoglobulin kappa variable 3-2
chr19_+_11482121 5.146 NM_029499
Ms4a4c
membrane-spanning 4-domains, subfamily A, member 4C
chr13_-_27530465 5.084 NM_011167
Prl8a6
prolactin family 8, subfamily a, member 6
chr3_-_10208575 5.072 NM_024406
Fabp4
fatty acid binding protein 4, adipocyte
chr5_+_119214935 5.070 Med13l
mediator complex subunit 13-like
chr6_+_70557402 5.069


chr3_-_14778441 5.025 NM_001083957
Car1
carbonic anhydrase 1
chr1_+_182981367 5.022 NM_001033819
9130409I23Rik
RIKEN cDNA 9130409I23 gene
chr6_-_124586102 4.968 NM_173864
Gm5077
predicted gene 5077
chr11_+_96184439 4.954 NM_001079869
Hoxb3
homeobox B3
chr13_+_49639847 4.952 Aspn
asporin
chr5_+_90919768 4.942 Afp
alpha fetoprotein
chr2_+_74707394 4.899 Mtx2
metaxin 2
chr2_-_103143352 4.896 NM_007914
Ehf
ets homologous factor
chr3_-_144512249 4.873 NM_139148
Clca4
chloride channel calcium activated 4
chr6_-_16848352 4.871 NM_031198
Tcfec
transcription factor EC
chr6_-_69557773 4.857


chr5_+_35384200 4.852 NM_019447
Hgfac
hepatocyte growth factor activator
chr2_-_180976728 4.818 NM_183162
BC006779
cDNA sequence BC006779
chr2_-_155771090 4.801 NM_008109
Gdf5
growth differentiation factor 5
chr16_-_33961960 4.755 Umps
uridine monophosphate synthetase
chr10_-_67741461 4.751 NM_023598
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr4_-_118954780 4.738 Ybx1
Y box protein 1
chr7_-_31900188 4.736 NM_001110252
NM_008281
Hpn

hepsin

chr7_-_29678773 4.716 Actn4
actinin alpha 4
chr1_-_137155012 4.686 NM_001163131
NM_007921
Elf3

E74-like factor 3

chr1_+_159436875 4.685 NM_033354
Sec16b
SEC16 homolog B (S. cerevisiae)
chr7_-_52714483 4.668 Ftl1
ferritin light chain 1
chr7_+_138175581 4.667 NM_007769
Dmbt1
deleted in malignant brain tumors 1
chr5_+_35384213 4.645 Hgfac
hepatocyte growth factor activator
chr6_-_138028436 4.641 NM_177787
Slc15a5
solute carrier family 15, member 5
chr11_-_83391984 4.619 Ccl9
chemokine (C-C motif) ligand 9
chr5_+_90919758 4.610 Afp
alpha fetoprotein
chr5_+_88885015 4.598 NM_009664
Ambn
ameloblastin
chr19_+_39081508 4.565 NM_028089
Cyp2c55
cytochrome P450, family 2, subfamily c, polypeptide 55
chr1_-_138856866 4.552 NM_030676
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr7_+_21657274 4.543 NM_001166744
Vmn1r116
vomeronasal 1 receptor 116
chr19_+_11518042 4.527 NM_021718
Ms4a4b
membrane-spanning 4-domains, subfamily A, member 4B
chr16_+_5007426 4.520 Gm5480
predicted gene 5480
chr3_-_14808320 4.426 NM_009799
Car1
carbonic anhydrase 1
chr11_+_87476588 4.398 NM_172448
Rnf43
ring finger protein 43

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.42 7.01e-06 GO:0048522 positive regulation of cellular process
1.39 7.04e-06 GO:0048518 positive regulation of biological process
1.41 8.64e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.33 9.74e-06 GO:0080090 regulation of primary metabolic process
1.43 1.05e-05 GO:0051252 regulation of RNA metabolic process
1.75 1.09e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.82 1.17e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.41 1.20e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.42 1.61e-05 GO:0009059 macromolecule biosynthetic process
1.43 1.75e-05 GO:0006355 regulation of transcription, DNA-dependent
1.20 1.94e-05 GO:0008152 metabolic process
1.33 2.55e-05 GO:0060255 regulation of macromolecule metabolic process
1.79 2.57e-05 GO:0051254 positive regulation of RNA metabolic process
1.41 2.93e-05 GO:0034645 cellular macromolecule biosynthetic process
1.49 3.18e-05 GO:0048513 organ development
1.69 4.65e-05 GO:0031328 positive regulation of cellular biosynthetic process
1.38 4.69e-05 GO:0010468 regulation of gene expression
1.29 4.85e-05 GO:0019222 regulation of metabolic process
1.31 6.85e-05 GO:0031323 regulation of cellular metabolic process
1.67 7.46e-05 GO:0009891 positive regulation of biosynthetic process
1.38 9.14e-05 GO:0010467 gene expression
1.20 1.18e-04 GO:0044238 primary metabolic process
1.36 1.25e-04 GO:0031326 regulation of cellular biosynthetic process
1.35 1.75e-04 GO:0009889 regulation of biosynthetic process
1.64 2.25e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.70 2.46e-04 GO:0010628 positive regulation of gene expression
1.68 2.49e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.67 2.57e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.35 2.64e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.45 3.31e-04 GO:0032774 RNA biosynthetic process
1.35 3.46e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 4.66e-04 GO:0006351 transcription, DNA-dependent
1.51 8.88e-04 GO:0031325 positive regulation of cellular metabolic process
1.82 9.21e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.68 1.28e-03 GO:0048584 positive regulation of response to stimulus
1.36 1.34e-03 GO:0016070 RNA metabolic process
1.48 1.79e-03 GO:0009893 positive regulation of metabolic process
1.22 1.89e-03 GO:0043170 macromolecule metabolic process
1.63 4.23e-03 GO:0009790 embryo development
1.29 4.28e-03 GO:0044249 cellular biosynthetic process
1.60 4.93e-03 GO:2000026 regulation of multicellular organismal development
1.32 5.12e-03 GO:0048856 anatomical structure development
1.28 6.65e-03 GO:0009058 biosynthetic process
2.10 7.82e-03 GO:0001501 skeletal system development
2.48 8.52e-03 GO:0048545 response to steroid hormone stimulus
1.27 9.06e-03 GO:0032502 developmental process
1.33 9.17e-03 GO:0048731 system development
1.33 1.00e-02 GO:0048519 negative regulation of biological process
1.17 1.17e-02 GO:0044237 cellular metabolic process
1.45 1.30e-02 GO:0009653 anatomical structure morphogenesis
2.36 1.32e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.46 1.57e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.30 1.59e-02 GO:0008202 steroid metabolic process
1.51 2.06e-02 GO:0050793 regulation of developmental process
1.40 2.06e-02 GO:0048583 regulation of response to stimulus
1.92 2.72e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.73 2.73e-02 GO:0051094 positive regulation of developmental process
3.71 3.75e-02 GO:0006959 humoral immune response
1.77 3.77e-02 GO:0043066 negative regulation of apoptosis
1.24 3.83e-02 GO:0006807 nitrogen compound metabolic process
1.20 4.33e-02 GO:0044260 cellular macromolecule metabolic process
1.28 4.49e-02 GO:0090304 nucleic acid metabolic process
1.25 4.50e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.25 7.37e-06 GO:0005634 nucleus
1.47 9.95e-06 GO:0005576 extracellular region
2.12 1.58e-04 GO:0005792 microsome
2.07 3.44e-04 GO:0042598 vesicular fraction
1.11 3.51e-04 GO:0005622 intracellular
1.12 3.54e-04 GO:0044424 intracellular part
1.15 6.06e-04 GO:0043227 membrane-bounded organelle
1.14 1.23e-03 GO:0043231 intracellular membrane-bounded organelle
1.63 1.56e-03 GO:0005615 extracellular space
1.53 2.02e-03 GO:0044421 extracellular region part
1.12 2.36e-03 GO:0043226 organelle
1.12 6.26e-03 GO:0043229 intracellular organelle
1.87 1.98e-02 GO:0005667 transcription factor complex
1.35 3.61e-02 GO:0005829 cytosol
1.32 4.18e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.99 1.17e-09 GO:0001071 nucleic acid binding transcription factor activity
1.99 1.17e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
2.05 3.48e-09 GO:0043565 sequence-specific DNA binding
1.55 1.00e-07 GO:0003677 DNA binding
1.43 2.45e-07 GO:0003676 nucleic acid binding
1.77 5.31e-07 GO:0030528 transcription regulator activity
1.14 8.00e-07 GO:0005488 binding
1.22 2.86e-05 GO:0005515 protein binding
2.03 1.24e-03 GO:0016564 transcription repressor activity
4.10 4.95e-03 GO:0043498 cell surface binding
2.57 6.66e-03 GO:0004497 monooxygenase activity
2.15 1.18e-02 GO:0000975 regulatory region DNA binding
2.15 1.18e-02 GO:0001067 regulatory region nucleic acid binding
2.15 1.18e-02 GO:0044212 transcription regulatory region DNA binding
1.85 2.47e-02 GO:0016563 transcription activator activity
2.27 4.30e-02 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen