Motif ID: AGCUUAU

Z-value: 1.120


Mature miRNA associated with seed AGCUUAU:

NamemiRBase Accession
mmu-miR-21 MIMAT0000530
mmu-miR-590-5p MIMAT0004895



Activity profile for motif AGCUUAU.

activity profile for motif AGCUUAU


Sorted Z-values histogram for motif AGCUUAU

Sorted Z-values for motif AGCUUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUUAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_51971946 18.669 NM_009122
Satb1
special AT-rich sequence binding protein 1
chr17_-_51951378 16.771 NM_001163630
Satb1
special AT-rich sequence binding protein 1
chr17_-_51972514 16.387 NM_001163632
Satb1
special AT-rich sequence binding protein 1
chr13_+_56710896 14.486 NM_009369
Tgfbi
transforming growth factor, beta induced
chr17_-_51965912 14.095 NM_001163631
Satb1
special AT-rich sequence binding protein 1
chr15_+_80541675 13.252 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr15_+_80629020 12.274 NM_177124
Tnrc6b
trinucleotide repeat containing 6b
chr4_+_43888373 12.248 NM_016678
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr13_-_102462584 11.927 NM_001024955
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr13_-_112599181 11.905 NM_011945
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr1_-_158869401 11.581 NM_001159966
Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr1_-_158869650 10.331 NM_001159965
NM_001159967
NM_001159968
NM_023884
Ralgps2



Ral GEF with PH domain and SH3 binding motif 2



chr19_+_53966720 9.939 NM_011050
Pdcd4
programmed cell death 4
chr18_+_75527015 9.834 NM_001042660
Smad7
MAD homolog 7 (Drosophila)
chr2_+_3630729 8.802 NM_025626
Fam107b
family with sequence similarity 107, member B
chr6_-_39156706 8.715 NM_001033430
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr9_-_85220730 8.465 NM_001160378
NM_001160379
Fam46a

family with sequence similarity 46, member A

chr6_-_14705104 8.389 NM_080464
Ppp1r3a
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr18_+_56591785 8.358 NM_026240
Gramd3
GRAM domain containing 3
chr11_+_85646116 8.188 NM_009324
Tbx2
T-box 2
chr4_+_97248556 7.990 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr1_-_135975681 7.693 NM_007570
Btg2
B-cell translocation gene 2, anti-proliferative
chr13_-_102538106 7.692 NM_001077495
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr9_-_8004559 7.202 NM_001171147
NM_009534
Yap1

yes-associated protein 1

chr11_-_118947424 7.072 NM_007625
Cbx4
chromobox homolog 4 (Drosophila Pc class)
chr15_+_85565935 7.057 NM_001113418
Ppara
peroxisome proliferator activated receptor alpha
chr4_+_97444312 6.886 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr3_-_9833502 6.832 NM_001195031
NM_053182
Pag1

phosphoprotein associated with glycosphingolipid microdomains 1

chr6_+_8459595 6.649 NM_133236
Glcci1
glucocorticoid induced transcript 1
chr4_+_8618067 6.640 NM_001081417
Chd7
chromodomain helicase DNA binding protein 7
chr1_-_74170987 6.421 NM_027884
Tns1
tensin 1
chr3_+_60305108 6.326 NM_020007
Mbnl1
muscleblind-like 1 (Drosophila)
chr15_+_85566122 6.306 NM_011144
Ppara
peroxisome proliferator activated receptor alpha
chr18_+_84257471 6.169 NM_146090
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr14_+_18814157 6.080 NM_009380
Thrb
thyroid hormone receptor beta
chrX_+_39503858 5.889 NM_021465
Stag2
stromal antigen 2
chr3_-_51129908 5.391 NM_023502
Elf2
E74-like factor 2
chr14_+_18493380 5.354 NM_001113417
Thrb
thyroid hormone receptor beta
chr17_+_25325344 4.993 NM_001197024
Unkl
unkempt-like (Drosophila)
chr3_-_131047840 4.943 NM_028943
Sgms2
sphingomyelin synthase 2
chr9_-_116084395 4.883 NM_009371
NM_029575
Tgfbr2

transforming growth factor, beta receptor II

chr9_+_109778051 4.861 NM_007658
Cdc25a
cell division cycle 25 homolog A (S. pombe)
chr19_+_53977788 4.748 NM_001168491
NM_001168492
Pdcd4

programmed cell death 4

chr11_+_60230646 4.745 NM_025757
4933439F18Rik
RIKEN cDNA 4933439F18 gene
chr1_+_132613903 4.375 NM_178691
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr6_-_71390592 4.373 NM_024288
Rmnd5a
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_-_126114938 4.321 NM_001164035
Ntf3
neurotrophin 3
chr3_+_128916849 4.287 NM_001042502
Pitx2
paired-like homeodomain transcription factor 2
chr8_+_36438761 4.156 NM_177741
Ppp1r3b
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr17_+_25359526 4.140 NM_028789
Unkl
unkempt-like (Drosophila)
chr6_+_88148657 4.058 NM_008090
Gata2
GATA binding protein 2
chr2_-_136942066 4.041 NM_013822
Jag1
jagged 1
chrX_+_39502588 4.011 NM_001077712
Stag2
stromal antigen 2
chrX_+_156828621 3.958 NM_001079847
NM_001079848
NM_001079857
NM_178712
Gpr64



G protein-coupled receptor 64



chr4_+_125781197 3.925 NM_001145827
NM_028800
Stk40

serine/threonine kinase 40

chr3_+_68494565 3.888 NM_001159424
Il12a
interleukin 12a
chr5_+_148242018 3.851 NM_028291
Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr3_+_128902822 3.798 NM_011098
NM_001042504
Pitx2

paired-like homeodomain transcription factor 2

chr2_-_102741782 3.728 NM_001039150
NM_001039151
NM_001177785
NM_001177786
NM_001177787
NM_009851
Cd44





CD44 antigen





chr2_-_104334610 3.681 NM_001145824
NM_010434
Hipk3

homeodomain interacting protein kinase 3

chr3_+_37538808 3.551 NM_011896
Spry1
sprouty homolog 1 (Drosophila)
chr2_-_148233853 3.514 NM_009378
Thbd
thrombomodulin
chr10_+_85763156 3.478 NM_011595
Timp3
tissue inhibitor of metalloproteinase 3
chr3_-_37131486 3.466 NM_021782
Il21
interleukin 21
chr5_-_64360058 3.443 NM_145923
Rell1
RELT-like 1
chr4_-_154596628 3.414 NM_011385
Ski
ski sarcoma viral oncogene homolog (avian)
chr5_+_123794456 3.405 NM_029850
Bcl7a
B-cell CLL/lymphoma 7A
chr6_-_126116761 3.377 NM_001164034
NM_008742
Ntf3

neurotrophin 3

chr1_-_108610861 3.348 NM_009741
NM_177410
Bcl2

B-cell leukemia/lymphoma 2

chr14_+_64562509 3.293 NM_011446
Sox7
SRY-box containing gene 7
chr4_+_122673318 3.187 NM_008506
Mycl1
v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
chr4_-_82151180 3.165 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr3_+_68495345 3.151 NM_008351
Il12a
interleukin 12a
chr9_-_70504934 2.904 NM_172772
Fam63b
family with sequence similarity 63, member B
chr8_+_109817355 2.840 NM_018823
NM_133957
Nfat5

nuclear factor of activated T-cells 5

chr3_+_103083215 2.823 NM_001079830
NM_053170
Trim33

tripartite motif-containing 33

chrX_+_157600681 2.682 NM_133194
Scml2
sex comb on midleg-like 2 (Drosophila)
chr11_+_60745534 2.675 NM_008928
Map2k3
mitogen-activated protein kinase kinase 3
chr8_-_114400574 2.645 NM_025781
Tmem170
transmembrane protein 170
chr14_+_31832323 2.528 NM_001081251
Pbrm1
polybromo 1
chr11_-_81993292 2.517 NM_011329
Ccl1
chemokine (C-C motif) ligand 1
chr2_-_168032561 2.478 NM_009628
Adnp
activity-dependent neuroprotective protein
chr6_+_147039596 2.419 NM_001081237
Klhdc5
kelch domain containing 5
chr14_+_79826199 2.357 NM_001024135
Kbtbd7
kelch repeat and BTB (POZ) domain containing 7
chr12_+_9581218 2.343 NM_011859
Osr1
odd-skipped related 1 (Drosophila)
chr12_-_109241423 2.274 NM_001079883
NM_021399
Bcl11b

B-cell leukemia/lymphoma 11B

chr1_+_167718811 2.168 NM_001113391
NM_001113392
NM_001113393
NM_001113394
NM_031162
Cd247




CD247 antigen




chr16_+_4594703 2.162 NM_031184
Glis2
GLIS family zinc finger 2
chr8_-_48799252 2.116 NM_172407
Cdkn2aip
CDKN2A interacting protein
chr3_-_115710131 2.112 NM_023214
Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr4_-_19636000 2.090 NM_177327
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr5_-_46247789 2.079 NM_172153
Lcorl
ligand dependent nuclear receptor corepressor-like
chr19_+_7492081 2.058 NM_175381
2700081O15Rik
RIKEN cDNA 2700081O15 gene
chr13_+_49639799 2.057 NM_001172481
NM_025711
Aspn

asporin

chr1_-_17087821 2.032 NM_020604
Jph1
junctophilin 1
chr17_+_26852581 1.927 NM_029870
A930001N09Rik
RIKEN cDNA A930001N09 gene
chr11_-_100800603 1.818 NM_011486
NM_213659
NM_213660
Stat3


signal transducer and activator of transcription 3


chr1_-_163718415 1.685 NM_010177
Fasl
Fas ligand (TNF superfamily, member 6)
chr11_+_20991321 1.683 NM_023324
Peli1
pellino 1
chr4_+_133624366 1.640 NM_001162970
Aim1l
absent in melanoma 1-like
chr9_-_42913797 1.564 NM_027144
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chr8_-_72877137 1.410 NM_001122829
NM_030680
Upf1

UPF1 regulator of nonsense transcripts homolog (yeast)

chr15_-_73015345 1.406 NM_153178
Eif2c2
eukaryotic translation initiation factor 2C, 2
chr10_-_62342761 1.382 NM_027384
Tet1
tet oncogene 1
chr7_-_127039189 1.377 NM_001163703
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr15_+_102300972 1.371 NM_001103165
NM_001103166
NM_001174073
NM_011042
Pcbp2



poly(rC) binding protein 2



chr10_+_53316720 1.368 NM_025541
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr17_-_7165497 1.342 NM_147155
Tagap1
T-cell activation GTPase activating protein 1
chr3_+_97817440 1.311 NM_010928
Notch2
Notch gene homolog 2 (Drosophila)
chr7_+_73007017 1.269 NM_011048
Pcsk6
proprotein convertase subtilisin/kexin type 6
chr5_-_135870365 1.257 NM_148932
Pom121
nuclear pore membrane protein 121
chr7_-_127038916 1.204 NM_173408
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr9_-_96531911 1.186 NM_053268
Rasa2
RAS p21 protein activator 2
chr13_-_64254466 1.111 NM_175494
Zfp367
zinc finger protein 367
chr2_+_109757803 1.056 NM_172671
Lgr4
leucine-rich repeat-containing G protein-coupled receptor 4
chr17_+_29169579 1.056 NM_013663
Srsf3
serine/arginine-rich splicing factor 3
chr2_+_69735301 1.013 NM_001081548
NM_177783
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr4_-_133523750 1.000 NM_016957
Hmgn2
high mobility group nucleosomal binding domain 2
chr5_-_38215607 0.993 NM_010835
Msx1
homeobox, msh-like 1
chr19_+_45005608 0.889 NM_001081225
Fam178a
family with sequence similarity 178, member A
chr11_+_59475986 0.875 NM_012027
NM_201245
Mprip

myosin phosphatase Rho interacting protein

chr8_-_109620413 0.873 NM_001083118
NM_009353
Terf2

telomeric repeat binding factor 2

chr17_-_63849928 0.868 NM_015794
Fbxl17
F-box and leucine-rich repeat protein 17
chr2_+_59450080 0.860 NM_198294
Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr6_+_14851348 0.835 NM_053242
Foxp2
forkhead box P2
chr13_+_83643032 0.833 NM_001170537
NM_025282
Mef2c

myocyte enhancer factor 2C

chr11_+_98657082 0.780 NM_028722
Msl1
male-specific lethal 1 homolog (Drosophila)
chr16_-_89960987 0.762 NM_009384
Tiam1
T-cell lymphoma invasion and metastasis 1
chr2_-_152240762 0.748 NM_175126
Zcchc3
zinc finger, CCHC domain containing 3
chr9_+_51855254 0.670 NM_001104616
Rdx
radixin
chr12_+_84973146 0.624 NM_027349
AA645497
Rbm25
expressed sequence AA645497
RNA binding motif protein 25
chr14_+_67254087 0.621 NM_013461
Adra1a
adrenergic receptor, alpha 1a
chr11_-_82684653 0.588 NM_001007465
NM_001164569
NM_001164571
Rffl


ring finger and FYVE like domain containing protein


chr3_+_135101664 0.565 NM_025356
Ube2d3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr9_-_70351520 0.551 NM_033604
Rnf111
ring finger 111
chr10_-_102491392 0.540 NM_172553
Alx1
ALX homeobox 1
chr5_+_65928483 0.533 NM_016786
Ube2k
ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
chr2_+_153567020 0.505 NM_007896
Mapre1
microtubule-associated protein, RP/EB family, member 1
chr13_+_34967355 0.495 NM_013830
Prpf4b
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr10_+_42481292 0.476 NM_153055
Sec63
SEC63-like (S. cerevisiae)
chr1_-_107253245 0.437 NM_001160368
NM_178779
Rnf152

ring finger protein 152

chr6_+_15135505 0.429 NM_212435
Foxp2
forkhead box P2
chr13_+_5860701 0.405 NM_011803
Klf6
Kruppel-like factor 6
chr10_-_120416369 0.338 NM_001081193
Lemd3
LEM domain containing 3
chr2_+_118727248 0.323 NM_001045523
Bahd1
bromo adjacent homology domain containing 1
chr6_-_83781704 0.309 NM_146169
Paip2b
poly(A) binding protein interacting protein 2B
chr9_-_117539030 0.302 NM_001172121
Rbms3
RNA binding motif, single stranded interacting protein
chr6_-_86476063 0.279 NM_011865
Pcbp1
poly(rC) binding protein 1
chr2_+_90744878 0.243 NM_025991
Kbtbd4
kelch repeat and BTB (POZ) domain containing 4
chr10_+_58684631 0.237 NM_172939
Ankrd57
ankyrin repeat domain 57
chr11_-_82684245 0.231 NM_001164570
Rffl
ring finger and FYVE like domain containing protein
chr15_-_12522310 0.188 NM_001081064
Pdzd2
PDZ domain containing 2
chr7_+_138009310 0.143 NM_133942
Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr6_-_144157971 0.055 NM_001113559
NM_011444
Sox5

SRY-box containing gene 5

chr11_-_20149322 0.015 NM_172260
Cep68
centrosomal protein 68

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.69 1.53e-15 GO:0048519 negative regulation of biological process
3.03 3.91e-15 GO:0060255 regulation of macromolecule metabolic process
3.38 1.36e-14 GO:0010468 regulation of gene expression
3.74 3.09e-14 GO:0048523 negative regulation of cellular process
2.73 3.94e-14 GO:0019222 regulation of metabolic process
3.36 9.04e-14 GO:0010556 regulation of macromolecule biosynthetic process
2.86 1.53e-13 GO:0031323 regulation of cellular metabolic process
3.38 1.60e-13 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.83 4.98e-13 GO:0080090 regulation of primary metabolic process
3.18 1.01e-12 GO:0031326 regulation of cellular biosynthetic process
3.14 1.72e-12 GO:0009889 regulation of biosynthetic process
3.27 3.34e-11 GO:0051252 regulation of RNA metabolic process
3.02 7.54e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
5.05 1.00e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.99 1.14e-10 GO:0051171 regulation of nitrogen compound metabolic process
4.32 1.56e-10 GO:0010604 positive regulation of macromolecule metabolic process
4.24 2.66e-10 GO:0031325 positive regulation of cellular metabolic process
3.19 3.41e-10 GO:0006355 regulation of transcription, DNA-dependent
3.98 1.57e-09 GO:0009893 positive regulation of metabolic process
5.05 2.15e-09 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.80 2.63e-09 GO:0031328 positive regulation of cellular biosynthetic process
4.98 3.01e-09 GO:0010557 positive regulation of macromolecule biosynthetic process
4.92 3.85e-09 GO:0051173 positive regulation of nitrogen compound metabolic process
4.71 4.21e-09 GO:0009891 positive regulation of biosynthetic process
5.36 4.34e-09 GO:0045893 positive regulation of transcription, DNA-dependent
5.11 4.38e-09 GO:0010628 positive regulation of gene expression
2.25 4.68e-09 GO:0044260 cellular macromolecule metabolic process
5.28 6.02e-09 GO:0051254 positive regulation of RNA metabolic process
2.78 1.18e-08 GO:0048518 positive regulation of biological process
2.80 1.71e-08 GO:0090304 nucleic acid metabolic process
2.90 1.90e-08 GO:0048522 positive regulation of cellular process
2.95 3.77e-08 GO:0016070 RNA metabolic process
5.94 4.08e-08 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.61 1.09e-07 GO:0007275 multicellular organismal development
3.29 1.37e-07 GO:0006351 transcription, DNA-dependent
3.29 1.44e-07 GO:0032774 RNA biosynthetic process
2.50 1.66e-07 GO:0032502 developmental process
1.70 4.36e-07 GO:0050789 regulation of biological process
2.02 5.12e-07 GO:0043170 macromolecule metabolic process
1.73 5.43e-07 GO:0050794 regulation of cellular process
2.69 6.76e-07 GO:0010467 gene expression
3.17 7.45e-07 GO:0048513 organ development
2.57 2.55e-06 GO:0048856 anatomical structure development
2.67 4.34e-06 GO:0048731 system development
3.99 4.70e-06 GO:0010605 negative regulation of macromolecule metabolic process
2.36 5.47e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62 5.80e-06 GO:0065007 biological regulation
2.60 1.48e-05 GO:0034645 cellular macromolecule biosynthetic process
2.58 1.85e-05 GO:0009059 macromolecule biosynthetic process
3.69 2.16e-05 GO:0009892 negative regulation of metabolic process
3.95 2.67e-05 GO:0042127 regulation of cell proliferation
4.55 2.94e-05 GO:0010629 negative regulation of gene expression
4.46 3.93e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
4.29 7.38e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
3.68 9.54e-05 GO:0031324 negative regulation of cellular metabolic process
2.14 1.22e-04 GO:0034641 cellular nitrogen compound metabolic process
4.15 1.23e-04 GO:0031327 negative regulation of cellular biosynthetic process
4.28 1.71e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.05 1.77e-04 GO:0009890 negative regulation of biosynthetic process
4.22 2.15e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
2.88 2.37e-04 GO:0048583 regulation of response to stimulus
4.43 2.39e-04 GO:0009887 organ morphogenesis
2.08 2.68e-04 GO:0006807 nitrogen compound metabolic process
1.71 3.24e-04 GO:0044237 cellular metabolic process
3.71 3.36e-04 GO:0009888 tissue development
5.70 4.14e-04 GO:0008285 negative regulation of cell proliferation
1.67 7.44e-04 GO:0044238 primary metabolic process
4.25 9.57e-04 GO:0045892 negative regulation of transcription, DNA-dependent
25.77 1.13e-03 GO:0001709 cell fate determination
4.19 1.17e-03 GO:0051253 negative regulation of RNA metabolic process
2.87 1.28e-03 GO:0023051 regulation of signaling
2.52 1.38e-03 GO:0030154 cell differentiation
3.35 1.67e-03 GO:0042981 regulation of apoptosis
3.31 2.00e-03 GO:0043067 regulation of programmed cell death
4.91 2.19e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
7.74 2.22e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
3.04 2.33e-03 GO:0009966 regulation of signal transduction
2.45 2.54e-03 GO:0048869 cellular developmental process
6.58 2.59e-03 GO:0016567 protein ubiquitination
14.73 2.81e-03 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
3.22 2.98e-03 GO:0010941 regulation of cell death
2.08 3.06e-03 GO:0044249 cellular biosynthetic process
4.03 4.03e-03 GO:0002682 regulation of immune system process
6.27 4.04e-03 GO:0050778 positive regulation of immune response
5.55 4.28e-03 GO:0070647 protein modification by small protein conjugation or removal
6.14 4.82e-03 GO:0061061 muscle structure development
3.24 4.91e-03 GO:0032268 regulation of cellular protein metabolic process
6.05 5.53e-03 GO:0032446 protein modification by small protein conjugation
2.02 6.28e-03 GO:0009058 biosynthetic process
5.30 6.53e-03 GO:0035295 tube development
2.94 6.92e-03 GO:0007399 nervous system development
9.67 7.08e-03 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
5.16 8.48e-03 GO:0007420 brain development
5.14 8.72e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
7.59 9.40e-03 GO:0007517 muscle organ development
11.46 1.22e-02 GO:0000209 protein polyubiquitination
3.02 1.32e-02 GO:0050793 regulation of developmental process
7.24 1.33e-02 GO:0045165 cell fate commitment
6.19 1.36e-02 GO:0043193 positive regulation of gene-specific transcription
4.89 1.39e-02 GO:0007167 enzyme linked receptor protein signaling pathway
4.37 1.74e-02 GO:0007417 central nervous system development
2.96 1.80e-02 GO:0051246 regulation of protein metabolic process
2.92 2.13e-02 GO:0010646 regulation of cell communication
7.74 3.03e-02 GO:0002757 immune response-activating signal transduction
21.33 3.04e-02 GO:0030514 negative regulation of BMP signaling pathway
4.41 3.60e-02 GO:0002684 positive regulation of immune system process
7.52 3.62e-02 GO:0002764 immune response-regulating signaling pathway
154.58 3.65e-02 GO:0007521 muscle cell fate determination
4.34 4.14e-02 GO:0032583 regulation of gene-specific transcription
3.01 4.15e-02 GO:0002376 immune system process
12.47 4.36e-02 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
4.72 4.65e-02 GO:0050776 regulation of immune response
1.49 4.89e-02 GO:0008152 metabolic process
7.17 4.90e-02 GO:0014706 striated muscle tissue development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.00 3.63e-07 GO:0005634 nucleus
1.44 1.00e-05 GO:0005622 intracellular
1.43 2.07e-05 GO:0044424 intracellular part
1.46 2.42e-03 GO:0043231 intracellular membrane-bounded organelle
1.46 2.63e-03 GO:0043227 membrane-bounded organelle
1.40 5.08e-03 GO:0043229 intracellular organelle
1.40 5.72e-03 GO:0043226 organelle
2.29 7.08e-03 GO:0044428 nuclear part
2.57 4.92e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
5.50 1.40e-10 GO:0001071 nucleic acid binding transcription factor activity
5.50 1.40e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
2.95 2.36e-10 GO:0003676 nucleic acid binding
3.29 1.15e-08 GO:0003677 DNA binding
1.52 5.91e-08 GO:0005488 binding
5.14 9.60e-08 GO:0043565 sequence-specific DNA binding
1.84 4.75e-06 GO:0005515 protein binding
3.70 2.78e-05 GO:0030528 transcription regulator activity
2.97 1.08e-04 GO:0008270 zinc ion binding
5.16 1.39e-03 GO:0016563 transcription activator activity
7.11 2.47e-03 GO:0005126 cytokine receptor binding
2.48 2.65e-03 GO:0046914 transition metal ion binding
51.53 3.09e-03 GO:0000982 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
51.53 3.09e-03 GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
14.59 3.31e-03 GO:0046332 SMAD binding
6.76 3.56e-03 GO:0004842 ubiquitin-protein ligase activity
6.28 6.02e-03 GO:0019787 small conjugating protein ligase activity
4.30 7.42e-03 GO:0016874 ligase activity
6.10 7.44e-03 GO:0003682 chromatin binding
5.90 9.45e-03 GO:0000975 regulatory region DNA binding
5.90 9.45e-03 GO:0001067 regulatory region nucleic acid binding
5.90 9.45e-03 GO:0044212 transcription regulatory region DNA binding
5.55 1.44e-02 GO:0016881 acid-amino acid ligase activity
4.95 3.15e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
9.10 3.21e-02 GO:0031625 ubiquitin protein ligase binding
2.82 3.86e-02 GO:0019899 enzyme binding
5.50 4.18e-02 GO:0010843 promoter binding
5.44 4.45e-02 GO:0043566 structure-specific DNA binding