Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 2.085


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
Arnt 11863 aryl hydrocarbon receptor nuclear translocator
Arnt2 11864 aryl hydrocarbon receptor nuclear translocator 2
Bhlhe40 20893 basic helix-loop-helix family, member e40
Max 17187 Max protein
Myc 17869 myelocytomatosis oncogene
Usf1 22278 upstream transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mycchr15_+_618171020.572.2e-17Click!
Bhlhe40chr6_+_108610606-0.401.6e-08Click!
Maxchr12_-_780630110.138.2e-02Click!
Usf1chr1_+_1733418110.092.1e-01Click!
Arnt2chr7_-_91558468-0.064.2e-01Click!
Arntchr3_+_95238292-0.064.6e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_126500607 88.202 NM_009870
Cdk4
cyclin-dependent kinase 4
chr14_+_51544629 53.467 NM_009687
Apex1
apurinic/apyrimidinic endonuclease 1
chr9_+_21172314 41.889 NM_001042707
NM_001042708
NM_001042709
NM_010561
Ilf3



interleukin enhancer binding factor 3



chr19_-_4201541 41.200 NM_011237
Rad9
RAD9 homolog (S. pombe)
chr9_+_21216277 35.101 NM_021888
Qtrt1
queuine tRNA-ribosyltransferase 1
chr6_-_88848650 30.975 NM_008564
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr17_-_35137799 30.418 D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr1_+_59741800 30.387 NM_018868
Nop58
NOP58 ribonucleoprotein homolog (yeast)
chr11_+_69814046 30.196 NM_007888
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr4_+_147965596 26.175 NM_009272
Srm
spermidine synthase
chr5_-_138613028 26.148 NM_008568
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr4_+_134024234 25.763 NM_019641
Stmn1
stathmin 1
chr5_-_77380593 24.904 NM_172146
Ppat
phosphoribosyl pyrophosphate amidotransferase
chr7_-_52722144 24.873 NM_007527
Bax
BCL2-associated X protein
chr17_+_35137995 23.831 Vars
valyl-tRNA synthetase
chr17_-_35137690 22.958 D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr15_+_59205752 22.681 NM_001164604
NM_026746
Nsmce2

non-SMC element 2 homolog (MMS21, S. cerevisiae)

chr3_+_89577436 22.201 NM_027315
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chrX_-_131076136 21.868 NM_013898
Timm8a1
translocase of inner mitochondrial membrane 8 homolog a1 (yeast)
chr17_-_53828596 21.756 NM_028232
Sgol1
shugoshin-like 1 (S. pombe)
chr14_-_51544484 21.524 Osgep
O-sialoglycoprotein endopeptidase
chr4_-_34830178 20.053 NM_013889
Zfp292
zinc finger protein 292
chr14_-_51544362 19.729 Osgep
O-sialoglycoprotein endopeptidase
chrX_+_45499599 18.973 NM_028773
Sash3
SAM and SH3 domain containing 3
chr16_+_35770488 18.694 Hspbap1
Hspb associated protein 1
chrX_+_149574541 18.665 Rragb
Ras-related GTP binding B
chr3_-_89856250 18.527 NM_001165983
NM_001165985
NM_001165987
NM_028475
NM_153489
NM_001165984
NM_001165986
NM_001165988
Ubap2l







ubiquitin associated protein 2-like







chr2_+_158620555 17.424 NM_145742
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chrX_+_48194918 17.399 2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr10_+_43198945 17.397 NM_199028
Bend3
BEN domain containing 3
chrX_+_132804834 17.280 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr19_+_7049425 17.246 NM_008889
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chrX_+_149574498 17.133 NM_001004154
Rragb
Ras-related GTP binding B
chr11_-_93747039 17.063 NM_001013375
Utp18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr11_-_94515067 17.056 NM_177752
Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr8_+_120022149 16.794 NM_172285
Plcg2
phospholipase C, gamma 2
chr3_+_159158396 16.708 NM_001172092
NM_001172093
NM_029523
Depdc1a


DEP domain containing 1a


chrX_+_132804865 16.670 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr2_+_30141908 16.574 NM_198304
Nup188
nucleoporin 188
chr4_+_140258090 16.366 Rcc2
regulator of chromosome condensation 2
chr4_+_140257340 16.365 NM_173867
Rcc2
regulator of chromosome condensation 2
chr11_-_93746982 16.347 Utp18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr19_-_4615180 16.344 Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr11_-_94515034 16.270 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr17_+_29169612 16.232 Srsf3
serine/arginine-rich splicing factor 3
chr2_-_84510822 16.192 NM_001033166
NM_001037279
2700094K13Rik

RIKEN cDNA 2700094K13 gene

chr15_+_103070840 16.093 NM_001039129
NM_010447
Hnrnpa1

heterogeneous nuclear ribonucleoprotein A1

chr10_-_119913990 16.017 NM_010441
Hmga2
high mobility group AT-hook 2
chr17_-_33822327 15.858 NM_001109913
NM_029804
Hnrnpm

heterogeneous nuclear ribonucleoprotein M

chr3_+_67386633 15.744 NM_025813
Mfsd1
major facilitator superfamily domain containing 1
chr17_+_35137851 15.182 NM_011690
Vars
valyl-tRNA synthetase
chr17_+_29169579 14.975 NM_013663
Srsf3
serine/arginine-rich splicing factor 3
chr4_-_48486214 14.951 NM_172304
Tex10
testis expressed gene 10
chr3_+_152059620 14.884 NM_198416
Zzz3
zinc finger, ZZ domain containing 3
chr11_+_68859125 14.807 NM_011496
Aurkb
aurora kinase B
chr18_+_56867378 14.716 NM_010721
Lmnb1
lamin B1
chr5_-_136646451 14.705 NM_178751
Orai2
ORAI calcium release-activated calcium modulator 2
chr17_+_29169665 14.650 Srsf3
serine/arginine-rich splicing factor 3
chr16_-_5204069 14.570 Nagpa
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chrX_+_132804857 14.449 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_-_5204078 14.370 NM_013796
Nagpa
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr11_-_117641895 14.349 NM_181321
Tmc6
transmembrane channel-like gene family 6
chr10_+_82092582 14.328 NM_011561
NM_172552
Tdg

Gm9855
thymine DNA glycosylase

thymine DNA glycosylase pseudogene
chr17_+_45701100 14.125 NM_028662
Slc35b2
solute carrier family 35, member B2
chr1_+_168309297 14.047 NM_030245
Tada1
transcriptional adaptor 1
chr16_+_35770431 13.801 NM_175111
Hspbap1
Hspb associated protein 1
chr13_+_21272294 13.602 Trim27
tripartite motif-containing 27
chr1_+_174430081 13.371 Tagln2
transgelin 2
chr11_-_84326869 13.341 NM_019816
Aatf
apoptosis antagonizing transcription factor
chr10_+_79479416 13.326 NM_001142701
Hmha1
histocompatibility (minor) HA-1
chr11_+_87569075 13.249 A430104N18Rik
RIKEN cDNA A430104N18 gene
chr11_-_102742230 13.249 NM_001109995
NM_011431
Eftud2

elongation factor Tu GTP binding domain containing 2

chr1_-_60154406 13.006 Wdr12
WD repeat domain 12
chr17_+_46633703 12.951 NM_207161
BC048355
cDNA sequence BC048355
chr2_-_103601232 12.908 NM_153126
Nat10
N-acetyltransferase 10
chr3_-_101091814 12.877 NM_013486
Cd2
CD2 antigen
chr11_-_117641951 12.763 NM_145439
Tmc6
transmembrane channel-like gene family 6
chr17_+_71965554 12.761 NM_175639
Wdr43
WD repeat domain 43
chr19_-_4615460 12.754 Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr4_+_132091462 12.693 NM_172400
Dnajc8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr19_-_10278231 12.648 NM_007999
Fen1
flap structure specific endonuclease 1
chr14_-_51544497 12.502 NM_133676
Osgep
O-sialoglycoprotein endopeptidase
chr3_+_138190223 12.437 Eif4e
eukaryotic translation initiation factor 4E
chr3_-_107889507 12.284 NM_028779
Ampd2
adenosine monophosphate deaminase 2
chr7_-_52241669 12.262 NM_019830
Prmt1
protein arginine N-methyltransferase 1
chr5_-_111209468 12.251 NM_001025561
NM_019700
NM_001025562
Pus1


pseudouridine synthase 1


chr5_-_114280434 12.233 NM_009151
Selplg
selectin, platelet (p-selectin) ligand
chr5_+_110715337 12.088 NM_011132
Pole
polymerase (DNA directed), epsilon
chr8_+_87213209 11.970 Trmt1
TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)
chr4_-_133574655 11.927 NM_145833
Lin28a
lin-28 homolog A (C. elegans)
chr8_+_87213179 11.851 Trmt1
TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)
chr17_-_32540473 11.829 Rasal3
RAS protein activator like 3
chr5_-_77380189 11.816 Ppat
phosphoribosyl pyrophosphate amidotransferase
chr5_+_120566489 11.803 NM_028762
Rbm19
RNA binding motif protein 19
chr7_-_134404120 11.773 NM_023203
Dctpp1
dCTP pyrophosphatase 1
chr1_-_55144637 11.693 Hspd1
heat shock protein 1 (chaperonin)
chr2_+_75497282 11.608 NM_053263
NM_146130
NM_198090
Hnrnpa3


Gm6793
heterogeneous nuclear ribonucleoprotein A3


heterogeneous nuclear ribonucleoprotein A3 pseudogene
chrX_+_136991190 11.604 Prps1
phosphoribosyl pyrophosphate synthetase 1
chr1_-_55144687 11.534 NM_010477
Hspd1
heat shock protein 1 (chaperonin)
chr10_+_79317396 11.463 Ptbp1
polypyrimidine tract binding protein 1
chrX_+_132804791 11.388 NM_001110233
NM_001110234
NM_009750
Ngfrap1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr7_+_104845148 11.324 NM_023671
Clns1a
chloride channel, nucleotide-sensitive, 1A
chr19_-_4615661 11.302 NM_153388
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr5_-_77380226 11.239 Ppat
phosphoribosyl pyrophosphate amidotransferase
chr10_+_79317316 11.209 NM_001077363
NM_008956
Ptbp1

polypyrimidine tract binding protein 1

chr13_+_69750927 11.144 Nsun2
NOL1/NOP2/Sun domain family member 2
chr4_+_88783273 11.136 NM_024433
Mtap
methylthioadenosine phosphorylase
chr2_+_130100145 11.102 NM_024193
Nop56
NOP56 ribonucleoprotein homolog (yeast)
chr16_+_45224449 11.093 NM_001037719
NM_177584
Btla

B and T lymphocyte associated

chr15_-_96473193 10.974 NM_001166458
Slc38a1
solute carrier family 38, member 1
chr4_-_41222121 10.921 NM_026872
Ubap2
ubiquitin-associated protein 2
chr1_+_55145132 10.821 Hspe1
heat shock protein 1 (chaperonin 10)
chr3_+_105762425 10.788 Wdr77
WD repeat domain 77
chr3_+_102862151 10.781 NM_010937
Nras
neuroblastoma ras oncogene
chr17_-_32540518 10.777 NM_178785
Rasal3
RAS protein activator like 3
chr4_+_122960059 10.769 NM_130881
Pabpc4
poly(A) binding protein, cytoplasmic 4
chr10_+_5914137 10.720 NM_025343
Rmnd1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr4_-_136604609 10.715 NM_198248
Zbtb40
zinc finger and BTB domain containing 40
chr4_-_147412872 10.603 NM_011929
Clcn6
chloride channel 6
chr8_+_87213145 10.602 NM_001164559
NM_001164560
NM_198020
Trmt1


TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)


chr8_+_90796301 10.583 NM_007406
Adcy7
adenylate cyclase 7
chr1_+_89223558 10.537 NM_146112
NM_001110212
Gigyf2

GRB10 interacting GYF protein 2

chr7_-_52384104 10.463 NM_009438
Rpl13a
ribosomal protein L13A
chr15_-_59205688 10.392 NM_153548
E430025E21Rik
RIKEN cDNA E430025E21 gene
chr8_+_126545374 10.328 Urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr6_-_38249209 10.283 NM_172467
Zc3hav1l
zinc finger CCCH-type, antiviral 1-like
chr19_+_7049639 10.241 Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chrX_+_156065141 10.203 NM_001135727
Sh3kbp1
SH3-domain kinase binding protein 1
chr5_-_101227486 10.158 NM_001081107
Helq
helicase, POLQ-like
chr16_-_92826307 10.072 NM_001111021
NM_001111022
Runx1

runt related transcription factor 1

chr10_-_5913894 10.052 NM_024261
1700052N19Rik
RIKEN cDNA 1700052N19 gene
chr3_+_105762363 10.018 NM_027432
Wdr77
WD repeat domain 77
chr11_+_57822347 9.987 NM_028451
Larp1
La ribonucleoprotein domain family, member 1
chr17_-_25097542 9.954 NM_198937
Hn1l
hematological and neurological expressed 1-like
chr8_+_86239094 9.940 NM_197982
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr4_+_132091510 9.895 Dnajc8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr19_-_4615523 9.867 Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr3_+_137527575 9.867 H2afz
H2A histone family, member Z
chr15_+_101904294 9.825 Eif4b
eukaryotic translation initiation factor 4B
chr17_+_45700882 9.796 Slc35b2
solute carrier family 35, member B2
chr2_-_164658954 9.756 NM_001082974
Neurl2
neuralized-like 2 (Drosophila)
chr1_-_127808790 9.741 NM_145100
Lypd1
Ly6/Plaur domain containing 1
chr7_-_36587975 9.739 NM_177739
Zfp507
E130304I02Rik
zinc finger protein 507
RIKEN cDNA E130304I02 gene
chr1_-_127808723 9.637 Lypd1
Ly6/Plaur domain containing 1
chr12_+_17551771 9.621 Odc1
ornithine decarboxylase, structural 1
chr11_-_106993235 9.620 NM_176850
Bptf
bromodomain PHD finger transcription factor
chr4_-_120887671 9.524 Rlf
rearranged L-myc fusion sequence
chr18_+_75527015 9.482 NM_001042660
Smad7
MAD homolog 7 (Drosophila)
chrX_+_131135770 9.430 NM_019868
Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
chr9_+_35075447 9.414 NM_028040
Rpusd4
RNA pseudouridylate synthase domain containing 4
chr15_+_34425046 9.348 NM_026340
NM_152894
Pop1

processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)

chr18_+_12327237 9.225 NM_029623
3110002H16Rik
RIKEN cDNA 3110002H16 gene
chr9_+_106379599 9.219 NM_145620
Rrp9
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr9_-_22193627 9.208 NM_028390
Anln
anillin, actin binding protein
chrX_-_147531030 9.196 NM_001164578
NM_175146
Tsr2

TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)

chr10_-_77927652 9.144 NM_172134
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr5_-_72559220 9.094 NM_178599
Commd8
COMM domain containing 8
chr11_-_69734131 9.072 NM_001166590
Eif5a
eukaryotic translation initiation factor 5A
chr3_-_19935200 9.054 Hps3
Hermansky-Pudlak syndrome 3 homolog (human)
chr5_+_28492235 9.042 NM_010134
En2
engrailed 2
chr18_-_80348164 9.035 NM_175028
Adnp2
ADNP homeobox 2
chr1_+_168309525 9.009 Tada1
transcriptional adaptor 1
chr1_-_130488785 8.938 NM_009911
Cxcr4
chemokine (C-X-C motif) receptor 4
chr8_-_86222963 8.933 NM_177262
Pkn1
protein kinase N1
chr11_-_93829704 8.877 NM_008704
Nme1
non-metastatic cells 1, protein (NM23A) expressed in
chr12_+_17551678 8.874 NM_013614
Odc1
ornithine decarboxylase, structural 1
chr1_+_182781247 8.834 NM_145943
BC031781
cDNA sequence BC031781
chr3_+_137527448 8.803 NM_016750
H2afz
H2A histone family, member Z
chr6_-_128312829 8.761 5930416I19Rik
RIKEN cDNA 5930416I19 gene
chr10_-_17742931 8.753 NM_028440
3110003A17Rik
RIKEN cDNA 3110003A17 gene
chr14_-_52816830 8.752 NM_033618
Supt16h
suppressor of Ty 16 homolog (S. cerevisiae)
chr17_-_33783578 8.735 Hnrnpm
heterogeneous nuclear ribonucleoprotein M
chr2_+_31325763 8.710 NM_007494
Ass1
argininosuccinate synthetase 1
chr5_+_147760198 8.675 NM_025652
Gtf3a
general transcription factor III A
chr7_-_51787440 8.666 NM_019866
Spib
Spi-B transcription factor (Spi-1/PU.1 related)
chr8_+_96738490 8.633 NM_172410
Nup93
nucleoporin 93
chr16_+_44139908 8.630 NM_028108
Naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr17_-_24300592 8.613 NM_172935
Amdhd2
amidohydrolase domain containing 2
chrX_+_12858142 8.591 NM_010028
Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr3_+_89518943 8.578 NM_001038587
Adar
adenosine deaminase, RNA-specific
chr10_-_62801726 8.562 NM_001159590
NM_019812
NM_001159589
Sirt1


sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)


chr11_+_95198329 8.549 NM_172543
Fam117a
family with sequence similarity 117, memberA
chr19_-_40662819 8.509 NM_019698
NM_153554
Aldh18a1

aldehyde dehydrogenase 18 family, member A1

chr5_+_31357119 8.483 NM_023525
Cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr11_-_93829556 8.449 Nme1
non-metastatic cells 1, protein (NM23A) expressed in
chr11_-_17111513 8.411 Pno1
partner of NOB1 homolog (S. cerevisiae)
chr17_-_85189859 8.401 Lrpprc
leucine-rich PPR-motif containing
chr3_-_19935292 8.400 NM_001146323
NM_001146324
NM_080634
Hps3


Hermansky-Pudlak syndrome 3 homolog (human)


chr13_-_38750866 8.367 NM_025380
Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr3_-_129534032 8.360 Gar1
GAR1 ribonucleoprotein homolog (yeast)
chr9_-_95412264 8.343 NM_001114977
NM_026476
2610101N10Rik

RIKEN cDNA 2610101N10 gene

chr2_-_154394864 8.310 E2f1
E2F transcription factor 1
chr8_+_96738448 8.308 Nup93
nucleoporin 93
chrX_-_138159759 8.302 NM_010572
Irs4
insulin receptor substrate 4
chr8_-_126545208 8.260 NM_133966
Taf5l
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr12_-_80108263 8.238 NM_178745
Tmem229b
transmembrane protein 229B
chr5_-_100407613 8.234 Hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr5_+_38611707 8.217 NM_025281
Lyar
Ly1 antibody reactive clone
chr15_-_98711692 8.157 NM_026967
Rhebl1
Ras homolog enriched in brain like 1
chr12_-_77470450 8.100 NM_001172104
NM_028356
Zbtb25

zinc finger and BTB domain containing 25


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.69 9.07e-38 GO:0044260 cellular macromolecule metabolic process
1.89 1.77e-37 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.01 2.96e-36 GO:0010467 gene expression
1.82 3.42e-36 GO:0034641 cellular nitrogen compound metabolic process
1.53 2.34e-35 GO:0044237 cellular metabolic process
1.79 2.00e-34 GO:0006807 nitrogen compound metabolic process
1.61 9.58e-34 GO:0043170 macromolecule metabolic process
1.51 6.88e-33 GO:0044238 primary metabolic process
1.93 1.78e-32 GO:0090304 nucleic acid metabolic process
1.81 4.10e-30 GO:0009058 biosynthetic process
1.82 4.97e-30 GO:0044249 cellular biosynthetic process
1.97 1.44e-29 GO:0016070 RNA metabolic process
1.43 1.89e-29 GO:0008152 metabolic process
1.90 6.96e-27 GO:0009059 macromolecule biosynthetic process
1.91 8.49e-27 GO:0034645 cellular macromolecule biosynthetic process
1.84 1.14e-15 GO:0032774 RNA biosynthetic process
1.67 1.67e-15 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.84 1.97e-15 GO:0006351 transcription, DNA-dependent
1.62 1.50e-14 GO:0031326 regulation of cellular biosynthetic process
1.62 4.37e-14 GO:0010468 regulation of gene expression
1.60 4.72e-14 GO:0009889 regulation of biosynthetic process
1.63 5.00e-14 GO:0010556 regulation of macromolecule biosynthetic process
1.60 1.39e-13 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.65 1.52e-13 GO:0051252 regulation of RNA metabolic process
1.59 1.67e-13 GO:0051171 regulation of nitrogen compound metabolic process
1.65 3.23e-13 GO:0006355 regulation of transcription, DNA-dependent
1.49 1.83e-12 GO:0031323 regulation of cellular metabolic process
1.17 8.58e-12 GO:0009987 cellular process
2.46 8.69e-12 GO:0006396 RNA processing
1.47 9.53e-12 GO:0080090 regulation of primary metabolic process
1.46 1.22e-10 GO:0060255 regulation of macromolecule metabolic process
1.40 1.11e-09 GO:0019222 regulation of metabolic process
2.87 2.25e-09 GO:0006412 translation
1.57 4.28e-09 GO:0044267 cellular protein metabolic process
3.34 6.38e-09 GO:0034470 ncRNA processing
3.29 1.14e-08 GO:0022613 ribonucleoprotein complex biogenesis
3.19 1.80e-08 GO:0071843 cellular component biogenesis at cellular level
4.27 1.31e-07 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
4.50 1.94e-07 GO:0006403 RNA localization
2.85 3.16e-07 GO:0034660 ncRNA metabolic process
1.45 4.54e-07 GO:0019538 protein metabolic process
4.49 4.91e-07 GO:0050657 nucleic acid transport
4.49 4.91e-07 GO:0050658 RNA transport
4.49 4.91e-07 GO:0051236 establishment of RNA localization
2.48 7.87e-07 GO:0016568 chromatin modification
3.39 8.93e-07 GO:0006913 nucleocytoplasmic transport
3.32 1.61e-06 GO:0051169 nuclear transport
1.48 2.37e-06 GO:0071841 cellular component organization or biogenesis at cellular level
2.13 2.72e-06 GO:0051276 chromosome organization
3.37 6.45e-06 GO:0042254 ribosome biogenesis
2.28 7.13e-06 GO:0006325 chromatin organization
1.39 8.04e-06 GO:0071840 cellular component organization or biogenesis
4.38 1.07e-05 GO:0051028 mRNA transport
6.30 2.01e-05 GO:0006405 RNA export from nucleus
1.86 5.23e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.72 6.44e-05 GO:0006414 translational elongation
4.80 6.95e-05 GO:0051168 nuclear export
1.79 1.75e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.67 1.82e-04 GO:0044085 cellular component biogenesis
1.68 1.96e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.75 2.11e-04 GO:0007049 cell cycle
2.65 2.42e-04 GO:0016569 covalent chromatin modification
1.78 3.17e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.65 3.77e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.53 3.91e-04 GO:0006996 organelle organization
2.04 4.38e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.74 5.08e-04 GO:0009890 negative regulation of biosynthetic process
2.62 5.08e-04 GO:0016570 histone modification
8.09 6.58e-04 GO:0006400 tRNA modification
3.40 6.98e-04 GO:0006364 rRNA processing
3.28 7.88e-04 GO:0018205 peptidyl-lysine modification
1.78 8.13e-04 GO:0010629 negative regulation of gene expression
1.46 9.64e-04 GO:0043412 macromolecule modification
3.30 1.26e-03 GO:0016072 rRNA metabolic process
1.80 1.48e-03 GO:0051253 negative regulation of RNA metabolic process
1.80 1.65e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.59 1.89e-03 GO:0009892 negative regulation of metabolic process
1.74 1.94e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.75 2.04e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.51 2.76e-03 GO:0006473 protein acetylation
1.78 2.77e-03 GO:0046483 heterocycle metabolic process
2.22 3.04e-03 GO:0008380 RNA splicing
3.60 3.51e-03 GO:0008033 tRNA processing
3.60 3.51e-03 GO:0018394 peptidyl-lysine acetylation
4.38 4.07e-03 GO:0009451 RNA modification
2.35 4.54e-03 GO:0018130 heterocycle biosynthetic process
1.86 4.85e-03 GO:0006259 DNA metabolic process
1.58 5.56e-03 GO:0031324 negative regulation of cellular metabolic process
1.31 5.89e-03 GO:0016043 cellular component organization
1.37 6.05e-03 GO:0071842 cellular component organization at cellular level
5.76 7.72e-03 GO:0006406 mRNA export from nucleus
3.55 8.49e-03 GO:0016573 histone acetylation
1.81 8.85e-03 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.74 9.23e-03 GO:0046907 intracellular transport
1.51 9.44e-03 GO:0033036 macromolecule localization
1.93 9.55e-03 GO:0006974 response to DNA damage stimulus
3.13 9.80e-03 GO:0043543 protein acylation
2.12 1.04e-02 GO:0018193 peptidyl-amino acid modification
1.87 1.15e-02 GO:0044283 small molecule biosynthetic process
1.98 1.29e-02 GO:0016071 mRNA metabolic process
3.45 1.29e-02 GO:0006475 internal protein amino acid acetylation
3.45 1.29e-02 GO:0018393 internal peptidyl-lysine acetylation
2.01 1.53e-02 GO:0044271 cellular nitrogen compound biosynthetic process
1.57 3.57e-02 GO:0051649 establishment of localization in cell
2.80 3.59e-02 GO:0006399 tRNA metabolic process
2.03 3.80e-02 GO:0006281 DNA repair
1.85 4.30e-02 GO:0072521 purine-containing compound metabolic process
1.51 4.41e-02 GO:0051641 cellular localization
1.77 4.48e-02 GO:0006753 nucleoside phosphate metabolic process
1.77 4.48e-02 GO:0009117 nucleotide metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.35 7.41e-45 GO:0005622 intracellular
1.71 5.88e-44 GO:0005634 nucleus
1.36 4.23e-43 GO:0044424 intracellular part
1.41 3.02e-42 GO:0043226 organelle
1.41 7.98e-42 GO:0043229 intracellular organelle
1.46 8.64e-42 GO:0043231 intracellular membrane-bounded organelle
1.46 9.78e-42 GO:0043227 membrane-bounded organelle
2.22 2.61e-34 GO:0044428 nuclear part
2.22 4.28e-32 GO:0070013 intracellular organelle lumen
2.22 5.84e-32 GO:0043233 organelle lumen
2.19 2.28e-31 GO:0031974 membrane-enclosed lumen
2.27 2.30e-29 GO:0031981 nuclear lumen
1.54 5.01e-20 GO:0044446 intracellular organelle part
2.26 1.52e-19 GO:0005654 nucleoplasm
1.52 6.66e-19 GO:0044422 organelle part
1.31 1.01e-18 GO:0005737 cytoplasm
2.87 6.04e-14 GO:0005730 nucleolus
2.32 1.08e-13 GO:0044451 nucleoplasm part
1.51 2.72e-13 GO:0032991 macromolecular complex
1.34 8.44e-12 GO:0044444 cytoplasmic part
2.49 8.73e-12 GO:0030529 ribonucleoprotein complex
1.67 8.22e-09 GO:0005829 cytosol
1.10 4.25e-08 GO:0005623 cell
1.10 4.25e-08 GO:0044464 cell part
1.45 5.58e-07 GO:0043228 non-membrane-bounded organelle
1.45 5.58e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.41 7.50e-07 GO:0043234 protein complex
3.11 7.80e-06 GO:0016604 nuclear body
2.40 1.81e-03 GO:0005635 nuclear envelope
2.47 2.02e-03 GO:0005840 ribosome
2.03 2.83e-03 GO:0005667 transcription factor complex
3.66 3.27e-03 GO:0034708 methyltransferase complex
3.66 3.27e-03 GO:0035097 histone methyltransferase complex
2.23 6.37e-03 GO:0000228 nuclear chromosome
6.06 7.70e-03 GO:0031519 PcG protein complex
3.82 7.88e-03 GO:0016363 nuclear matrix
2.23 2.07e-02 GO:0044454 nuclear chromosome part
2.12 2.12e-02 GO:0000785 chromatin
3.15 3.90e-02 GO:0000123 histone acetyltransferase complex
2.67 4.24e-02 GO:0000790 nuclear chromatin

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.83 9.60e-26 GO:0003676 nucleic acid binding
2.60 1.57e-20 GO:0003723 RNA binding
1.21 6.51e-14 GO:0005488 binding
1.67 9.35e-11 GO:0003677 DNA binding
1.27 3.66e-06 GO:0003824 catalytic activity
1.45 7.12e-06 GO:0000166 nucleotide binding
3.71 8.13e-06 GO:0008135 translation factor activity, nucleic acid binding
1.23 6.53e-05 GO:0005515 protein binding
1.67 1.08e-04 GO:0030528 transcription regulator activity
2.10 1.14e-03 GO:0008134 transcription factor binding
1.42 2.82e-03 GO:0046914 transition metal ion binding
1.46 3.78e-03 GO:0008270 zinc ion binding
1.63 3.95e-03 GO:0001071 nucleic acid binding transcription factor activity
1.63 3.95e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.59 3.97e-03 GO:0019899 enzyme binding
1.38 7.08e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.38 8.00e-03 GO:0017076 purine nucleotide binding
1.37 9.53e-03 GO:0032555 purine ribonucleotide binding
1.37 9.84e-03 GO:0032553 ribonucleotide binding
1.25 1.23e-02 GO:0043169 cation binding
1.64 1.44e-02 GO:0043565 sequence-specific DNA binding
1.24 1.63e-02 GO:0043167 ion binding
1.25 1.73e-02 GO:0046872 metal ion binding
2.60 1.91e-02 GO:0016853 isomerase activity
2.07 2.47e-02 GO:0003712 transcription cofactor activity
2.06 2.69e-02 GO:0000989 transcription factor binding transcription factor activity
2.17 2.93e-02 GO:0043566 structure-specific DNA binding
2.58 3.07e-02 GO:0003735 structural constituent of ribosome
2.04 3.49e-02 GO:0000988 protein binding transcription factor activity
4.63 4.53e-02 GO:0003746 translation elongation factor activity