• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: ATF5_CREB3.p2

Z-value: 1.770

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_-_83936038	72.380		Sult4a1	sulfotransferase family 4A, member 1
chr2_+_136539202	47.976		Snap25	synaptosomal-associated protein 25
chr1_-_79436564	47.839	NM_009129	Scg2	secretogranin II
chr2_+_132607398	41.586		Chgb	chromogranin B
chr2_+_132607408	41.174		Chgb	chromogranin B
chr2_+_136539143	40.206	NM_011428	Snap25	synaptosomal-associated protein 25
chr2_+_132607432	39.936		Chgb	chromogranin B
chr8_-_73011217	36.145	NM_182991	Tmem59l	transmembrane protein 59-like
chr15_+_101097276	31.286	NM_010444	Nr4a1	nuclear receptor subfamily 4, group A, member 1
chr12_+_110779204	30.996		Meg3	maternally expressed 3
chr3_-_117063317	30.865		D3Bwg0562e	DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr8_+_73278577	29.630	NM_001166399 NM_009001	Rab3a	RAB3A, member RAS oncogene family
chr3_-_117063090	27.855		D3Bwg0562e	DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr13_+_58909254	27.182		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr2_+_177876710	27.129		Phactr3	phosphatase and actin regulator 3
chr2_+_177876635	26.159	NM_028806	Phactr3	phosphatase and actin regulator 3
chr1_+_63319842	25.763	NM_028673	Zdbf2	zinc finger, DBF-type containing 2
chr13_+_13876570	25.341		Gng4	guanine nucleotide binding protein (G protein), gamma 4
chr18_+_35020859	25.303	NM_007913	Egr1	early growth response 1
chr13_+_58909168	24.035	NM_001025074	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr18_+_35020867	23.962		Egr1	early growth response 1
chr5_+_137506122	23.391	NM_001039385	Vgf	VGF nerve growth factor inducible
chr6_-_124414668	22.493	NM_153508	Clstn3	calsyntenin 3
chr4_+_84851330	22.130	NM_019535	Sh3gl2	SH3-domain GRB2-like 2
chr2_+_177876858	22.122		Phactr3	phosphatase and actin regulator 3
chr7_-_149280946	21.624		Dusp8	dual specificity phosphatase 8
chr14_+_68701838	21.577	NM_010910	Nefl	neurofilament, light polypeptide
chr6_-_58857000	21.268	NM_021432	Nap1l5	nucleosome assembly protein 1-like 5
chrX_-_132738383	21.219	NM_177919	Tceal5	transcription elongation factor A (SII)-like 5
chr2_+_132607013	20.860	NM_007694	Chgb	chromogranin B
chr11_+_69154265	20.821		A030009H04Rik	RIKEN cDNA A030009H04 gene
chr17_+_37187550	20.660		Gabbr1	gamma-aminobutyric acid (GABA) B receptor, 1
chr4_+_48058102	20.547		Nr4a3	nuclear receptor subfamily 4, group A, member 3
chr7_-_134093094	20.452	NM_001039645	Asphd1	aspartate beta-hydroxylase domain containing 1
chr5_+_25265761	20.261	NM_001004365	Actr3b	ARP3 actin-related protein 3 homolog B (yeast)
chr12_-_73509925	19.941	NM_153457	Rtn1	reticulon 1
chr7_+_134094045	19.402	NM_144926	Sez6l2	seizure related 6 homolog like 2
chr2_-_56976413	19.398	NM_001139509	Nr4a2	nuclear receptor subfamily 4, group A, member 2
chr12_-_73509668	19.330		Rtn1	reticulon 1
chr9_-_75531734	19.090	NM_001164790 NM_009130	Scg3	secretogranin III
chr12_-_73509537	18.879		Rtn1	reticulon 1
chr8_-_74195650	18.847	NM_001029873	Unc13a	unc-13 homolog A (C. elegans)
chr11_+_102254816	18.594		Rundc3a	RUN domain containing 3A
chr9_-_52487410	18.349	NM_178906	AI593442	expressed sequence AI593442
chr4_+_84851440	18.305		Sh3gl2	SH3-domain GRB2-like 2
chr13_+_13876667	18.216	NM_010317	Gng4	guanine nucleotide binding protein (G protein), gamma 4
chr13_+_75227306	17.951	NM_013628	Pcsk1	proprotein convertase subtilisin/kexin type 1
chr6_-_8728094	17.648		Ica1	islet cell autoantigen 1
chr13_+_58909236	17.535		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr13_-_105844882	17.502	NM_029879	Rgs7bp	regulator of G-protein signalling 7 binding protein
chr15_-_44584003	17.392	NM_178765	Sybu	syntabulin (syntaxin-interacting)
chr2_+_92755251	17.373	NM_030725	Syt13	synaptotagmin XIII
chr10_+_20672352	17.190	NM_026203	Ahi1	Abelson helper integration site 1
chr19_-_5085487	17.055		Tmem151a	transmembrane protein 151A
chrX_+_162676903	16.899		Gpm6b	glycoprotein m6b
chr9_-_97933599	16.863		Clstn2	calsyntenin 2
chr12_+_4082739	16.828		Dnajc27	DnaJ (Hsp40) homolog, subfamily C, member 27
chrX_+_162676870	16.755	NM_001177961 NM_001177962 NM_023122	Gpm6b	glycoprotein m6b
chr12_+_103793130	16.664	NM_007693	Chga	chromogranin A
chr11_+_102254699	16.609	NM_016759	Rundc3a	RUN domain containing 3A
chr15_-_83936183	16.267	NM_013873	Sult4a1	sulfotransferase family 4A, member 1
chr2_+_143371807	16.005	NM_008792	Pcsk2	proprotein convertase subtilisin/kexin type 2
chr6_-_8728481	15.819	NM_010492	Ica1	islet cell autoantigen 1
chr18_-_35374663	15.764	NM_178005	Lrrtm2	leucine rich repeat transmembrane neuronal 2
chr18_-_31606908	15.532	NM_009308	Syt4	synaptotagmin IV
chr2_-_56967331	15.372	NM_013613	Nr4a2	nuclear receptor subfamily 4, group A, member 2
chr11_-_90252208	15.251		Hlf	hepatic leukemia factor
chr13_-_34169854	15.131	NM_009450	Tubb2a	tubulin, beta 2A
chr4_+_137220675	15.116		Rap1gap	Rap1 GTPase-activating protein
chr6_+_7505070	14.978	NM_009311	Tac1	tachykinin 1
chr9_-_97933533	14.894	NM_022319	Clstn2	calsyntenin 2
chr19_-_5085471	14.507	NM_001001885	Tmem151a	transmembrane protein 151A
chr18_-_35374531	14.248		Lrrtm2	leucine rich repeat transmembrane neuronal 2
chr4_-_150482562	14.239		Camta1	calmodulin binding transcription activator 1
chr17_+_37187984	14.209		Gabbr1	gamma-aminobutyric acid (GABA) B receptor, 1
chr16_-_23890909	14.136	NM_009215	Sst	somatostatin
chr7_-_6683113	13.971	NM_008817	Peg3	paternally expressed 3
chr13_+_54472806	13.949		Cplx2	complexin 2
chrX_-_132602648	13.811	NM_009749	Bex2	brain expressed X-linked 2
chr11_+_102254949	13.782		Rundc3a	RUN domain containing 3A
chr5_+_37633317	13.707	NM_001136058	Crmp1	collapsin response mediator protein 1
chr10_+_34017221	13.551	NM_030203	Tspyl4	TSPY-like 4
chr1_-_75260687	13.351	NM_008985	Ptprn	protein tyrosine phosphatase, receptor type, N
chr9_+_36640268	13.340		Fez1	fasciculation and elongation protein zeta 1 (zygin I)
chr1_+_75476106	13.216	NM_177056	Tmem198	transmembrane protein 198
chr12_+_4082573	13.195	NM_153082	Dnajc27	DnaJ (Hsp40) homolog, subfamily C, member 27
chr5_+_37633353	13.024		Crmp1	collapsin response mediator protein 1
chr4_-_11893500	12.938	NM_001033453 NM_001098230	Pdp1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr15_-_37389073	12.736	NM_001170867 NM_001170868	Ncald	neurocalcin delta
chrX_-_20498021	12.515	NM_001110780 NM_013680	Syn1	synapsin I
chr11_+_23978110	12.419		Bcl11a	B-cell CLL/lymphoma 11A (zinc finger protein)
chr4_+_84851029	12.414		Sh3gl2	SH3-domain GRB2-like 2
chr9_+_89804612	12.354	NM_001039655 NM_011245	Rasgrf1	RAS protein-specific guanine nucleotide-releasing factor 1
chr2_+_49474775	12.237	NM_008449	Kif5c	kinesin family member 5C
chr17_-_57226987	12.191	NM_009451	Tubb4	tubulin, beta 4
chr19_-_4989865	12.177	NM_153553	Npas4	neuronal PAS domain protein 4
chr2_-_113669159	12.126		Scg5	secretogranin V
chr4_+_138012860	12.008		Camk2n1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr11_-_70501430	12.007		Camta2	calmodulin binding transcription activator 2
chr11_+_92960603	11.780	NM_028296	Car10	carbonic anhydrase 10
chr14_-_55531726	11.674	NM_021551	Slc22a17	solute carrier family 22 (organic cation transporter), member 17
chr2_-_56976530	11.656		Nr4a2	nuclear receptor subfamily 4, group A, member 2
chr10_-_18463500	11.621	NM_001033258	D10Bwg1379e	DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr14_-_94289847	11.614		Pcdh9	protocadherin 9
chr7_-_112717810	11.598		Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1
chr13_+_58909648	11.534		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr1_+_154802144	11.519		Nmnat2	nicotinamide nucleotide adenylyltransferase 2
chr13_+_58909632	11.498		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr1_+_154802091	11.463		Nmnat2	nicotinamide nucleotide adenylyltransferase 2
chr12_+_86814822	11.371	NM_010234	Fos	FBJ osteosarcoma oncogene
chr11_-_70501586	11.318	NM_001190376 NM_001190378 NM_001190379 NM_178116	Camta2	calmodulin binding transcription activator 2
chr4_+_102432879	11.296		Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1
chr9_-_121404799	11.209	NM_031161	Cck	cholecystokinin
chr16_+_55973916	11.005	NM_173026	Zbtb11	zinc finger and BTB domain containing 11
chr2_+_158436493	10.951	NM_009508	Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1
chr15_+_81767188	10.909	NM_145473	Csdc2	cold shock domain containing C2, RNA binding
chr5_-_108978950	10.836	NM_007756	Cplx1	complexin 1
chr7_-_150085870	10.779	NM_009377	Th	tyrosine hydroxylase
chr13_+_94073701	10.667		Homer1	homer homolog 1 (Drosophila)
chr11_-_96805092	10.634		Pnpo	pyridoxine 5'-phosphate oxidase
chrX_+_5624820	10.534		Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr3_-_80717517	10.365	NM_010298	Glrb	glycine receptor, beta subunit
chr7_-_19895354	10.231	NM_008036	Fosb	FBJ osteosarcoma oncogene B
chr9_-_64101429	10.216		Map2k1	mitogen-activated protein kinase kinase 1
chr3_+_95428870	10.121	NM_001026212 NM_019561	Ensa	endosulfine alpha
chr4_-_91038638	9.994		Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_+_75878452	9.916	NM_178673	Fstl5	follistatin-like 5
chr2_+_49474840	9.870		Kif5c	kinesin family member 5C
chr6_-_85463535	9.780	NM_020596	Egr4	early growth response 4
chrX_+_162782484	9.729	NM_001177955 NM_001177956 NM_001177957 NM_001177958 NM_001177959 NM_001177960	Gpm6b	glycoprotein m6b
chr11_-_116442760	9.703	NM_173755	Ube2o	ubiquitin-conjugating enzyme E2O
chr2_-_32702610	9.679		Stxbp1	syntaxin binding protein 1
chr11_+_68901989	9.641		Vamp2	vesicle-associated membrane protein 2
chrX_+_162676910	9.593		Gpm6b	glycoprotein m6b
chr4_-_154719834	9.576	NM_001039079	Prkcz	protein kinase C, zeta
chr6_+_143115732	9.541	NM_029250	Etnk1	ethanolamine kinase 1
chr4_-_154719714	9.541		Prkcz	protein kinase C, zeta
chr3_+_55265811	9.451		Dclk1	doublecortin-like kinase 1
chr1_+_154802198	9.446	NM_175460	Nmnat2	nicotinamide nucleotide adenylyltransferase 2
chr12_-_36768992	9.417		Tspan13	tetraspanin 13
chr7_-_25772525	9.387		Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide
chrX_-_100381973	9.195	NM_008671	Nap1l2	nucleosome assembly protein 1-like 2
chr8_+_112603609	9.062	NM_175480	Zfp612	zinc finger protein 612
chr13_-_117099629	9.061	NM_021459	Isl1	ISL1 transcription factor, LIM/homeodomain
chr9_-_64101354	9.038	NM_008927	Map2k1	mitogen-activated protein kinase kinase 1
chr5_+_33361386	9.028	NM_011738	Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr4_+_101223198	8.974	NM_001164583	Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_-_113739711	8.955	NM_001162965 NM_172718	Sgsm1	small G protein signaling modulator 1
chr2_+_155102040	8.954	NM_025735	Map1lc3a	microtubule-associated protein 1 light chain 3 alpha
chrX_+_5624624	8.936	NM_021431	Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr8_-_70342105	8.917	NM_027626	Psd3	pleckstrin and Sec7 domain containing 3
chr15_+_4325490	8.862	NM_177355	Plcxd3	phosphatidylinositol-specific phospholipase C, X domain containing 3
chr10_-_77875707	8.857	NM_010925	Rrp1	ribosomal RNA processing 1 homolog (S. cerevisiae)
chr17_-_56615861	8.593		Ptprs	protein tyrosine phosphatase, receptor type, S
chr11_+_16157685	8.579	NM_145967	Vstm2a	V-set and transmembrane domain containing 2A
chr17_-_24826812	8.566		Syngr3	synaptogyrin 3
chr6_+_77193078	8.558		Lrrtm1	leucine rich repeat transmembrane neuronal 1
chr9_-_121404750	8.556		Cck	cholecystokinin
chr12_-_36769054	8.545	NM_025359	Tspan13	tetraspanin 13
chr11_-_119409041	8.530	NM_008730	Nptx1	neuronal pentraxin 1
chr4_+_151712739	8.508	NM_001081376 NM_029216	Chd5	chromodomain helicase DNA binding protein 5
chr17_+_86567003	8.435	NM_011104	Prkce	protein kinase C, epsilon
chr11_-_90252228	8.399	NM_172563	Hlf	hepatic leukemia factor
chr8_+_128519295	8.388		Kcnk1	potassium channel, subfamily K, member 1
chr12_+_70994091	8.365	NM_178628	Atl1	atlastin GTPase 1
chr13_-_36826104	8.344		Nrn1	neuritin 1
chr9_+_89804723	8.296		Rasgrf1	RAS protein-specific guanine nucleotide-releasing factor 1
chr13_+_54472705	8.209	NM_009946	Cplx2	complexin 2
chr6_+_53989925	8.186	NM_001163640	Chn2	chimerin (chimaerin) 2
chr10_+_28931448	7.954	NM_001162537	9330159F19Rik	RIKEN cDNA 9330159F19 gene
chr1_-_171677653	7.951	NM_009062	Rgs4	regulator of G-protein signaling 4
chr9_-_64101138	7.867		Map2k1	mitogen-activated protein kinase kinase 1
chr11_+_23978029	7.843	NM_001159289 NM_016707	Bcl11a	B-cell CLL/lymphoma 11A (zinc finger protein)
chr2_+_28048511	7.839		Olfm1	olfactomedin 1
chr6_+_124881376	7.806	NM_001170341 NM_145385	Mlf2	myeloid leukemia factor 2
chr6_+_124881437	7.799		Mlf2	myeloid leukemia factor 2
chr19_+_59335367	7.779	NM_172523	Slc18a2	solute carrier family 18 (vesicular monoamine), member 2
chr11_+_29618696	7.757		Rtn4	reticulon 4
chr7_+_4874478	7.717		Nat14	N-acetyltransferase 14
chr13_-_34222209	7.717	NM_023716	Tubb2b	tubulin, beta 2B
chr16_+_94592307	7.662	NM_009441	Ttc3	tetratricopeptide repeat domain 3
chr6_+_77192839	7.621		Lrrtm1	leucine rich repeat transmembrane neuronal 1
chr18_+_35021288	7.577		Egr1	early growth response 1
chr5_+_73684087	7.557		Ociad1	OCIA domain containing 1
chr8_-_67171481	7.486		Cpe	carboxypeptidase E
chr16_+_94592373	7.469		Ttc3	tetratricopeptide repeat domain 3
chr6_+_124881472	7.443		Mlf2	myeloid leukemia factor 2
chr7_+_148247172	7.434	NM_177897	B4galnt4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr18_-_43059156	7.426		Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr12_-_17183330	7.416		Kcnf1	potassium voltage-gated channel, subfamily F, member 1
chr5_-_103640272	7.406	NM_001081567 NM_009158	Mapk10	mitogen-activated protein kinase 10
chr5_+_137729501	7.377	NM_009599	Ache	acetylcholinesterase
chr10_+_102830353	7.370	NM_175328	Slc6a15	solute carrier family 6 (neurotransmitter transporter), member 15
chrX_-_49033640	7.368	NM_015819	Hs6st2	heparan sulfate 6-O-sulfotransferase 2
chr10_-_57252251	7.332		Serinc1	serine incorporator 1
chr19_+_5689759	7.303		Map3k11	mitogen-activated protein kinase kinase kinase 11
chr5_+_73684069	7.280		Ociad1	OCIA domain containing 1
chr17_-_25974021	7.263	NM_144816	Rhbdl1	rhomboid, veinlet-like 1 (Drosophila)
chr11_-_35612058	7.248		Fbll1	fibrillarin-like 1
chr13_+_59234737	7.234		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.40	8.44e-19	GO:0044237	cellular metabolic process
1.43	1.62e-13	GO:0044260	cellular macromolecule metabolic process
1.34	4.81e-13	GO:0044238	primary metabolic process
1.30	1.26e-12	GO:0008152	metabolic process
1.36	1.08e-10	GO:0043170	macromolecule metabolic process
1.49	1.70e-10	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45	6.59e-10	GO:0034641	cellular nitrogen compound metabolic process
1.16	1.57e-09	GO:0009987	cellular process
1.42	7.26e-09	GO:0006807	nitrogen compound metabolic process
1.99	1.47e-08	GO:0051649	establishment of localization in cell
2.17	4.09e-08	GO:0046907	intracellular transport
1.87	4.24e-08	GO:0051641	cellular localization
1.45	7.65e-08	GO:0071840	cellular component organization or biogenesis
1.46	1.69e-07	GO:0016043	cellular component organization
1.53	2.76e-07	GO:0044267	cellular protein metabolic process
1.47	1.02e-06	GO:0010467	gene expression
1.46	1.07e-06	GO:0006810	transport
1.45	1.22e-06	GO:0051234	establishment of localization
1.38	1.66e-06	GO:0031323	regulation of cellular metabolic process
1.40	2.96e-06	GO:0051179	localization
1.48	3.15e-06	GO:0016070	RNA metabolic process
1.50	6.85e-06	GO:0071842	cellular component organization at cellular level
1.48	8.68e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.33	8.93e-06	GO:0019222	regulation of metabolic process
1.68	1.33e-05	GO:0033036	macromolecule localization
1.41	1.77e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.98	1.82e-05	GO:0016192	vesicle-mediated transport
1.56	1.83e-05	GO:0006464	protein modification process
2.05	2.45e-05	GO:0030182	neuron differentiation
3.54	2.69e-05	GO:0048193	Golgi vesicle transport
1.41	2.86e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.41	3.53e-05	GO:0010468	regulation of gene expression
1.53	3.74e-05	GO:0043412	macromolecule modification
1.82	4.53e-05	GO:0045184	establishment of protein localization
1.44	4.61e-05	GO:0051252	regulation of RNA metabolic process
1.40	5.50e-05	GO:0090304	nucleic acid metabolic process
1.42	6.33e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.82	6.36e-05	GO:0015031	protein transport
1.70	9.90e-05	GO:0008104	protein localization
1.33	1.14e-04	GO:0080090	regulation of primary metabolic process
2.31	1.49e-04	GO:0070647	protein modification by small protein conjugation or removal
1.42	1.51e-04	GO:0006355	regulation of transcription, DNA-dependent
2.33	1.60e-04	GO:0009259	ribonucleotide metabolic process
1.39	1.83e-04	GO:0019538	protein metabolic process
2.53	2.63e-04	GO:0009261	ribonucleotide catabolic process
1.66	3.02e-04	GO:0044248	cellular catabolic process
2.55	3.02e-04	GO:0009203	ribonucleoside triphosphate catabolic process
1.39	3.06e-04	GO:0010556	regulation of macromolecule biosynthetic process
2.00	3.17e-04	GO:0030030	cell projection organization
2.30	4.59e-04	GO:0009150	purine ribonucleotide metabolic process
2.23	4.82e-04	GO:0031175	neuron projection development
1.99	4.86e-04	GO:0006753	nucleoside phosphate metabolic process
1.99	4.86e-04	GO:0009117	nucleotide metabolic process
1.76	5.14e-04	GO:0048699	generation of neurons
1.54	5.17e-04	GO:0006996	organelle organization
1.73	6.22e-04	GO:0022008	neurogenesis
1.36	6.25e-04	GO:0031326	regulation of cellular biosynthetic process
2.06	6.64e-04	GO:0048666	neuron development
1.32	6.70e-04	GO:0060255	regulation of macromolecule metabolic process
2.47	6.85e-04	GO:0009143	nucleoside triphosphate catabolic process
2.51	7.07e-04	GO:0007409	axonogenesis
2.49	7.94e-04	GO:0009207	purine ribonucleoside triphosphate catabolic process
2.10	9.51e-04	GO:0007610	behavior
2.31	1.04e-03	GO:0009199	ribonucleoside triphosphate metabolic process
2.46	1.12e-03	GO:0009146	purine nucleoside triphosphate catabolic process
1.35	1.14e-03	GO:0009889	regulation of biosynthetic process
2.44	1.40e-03	GO:0009154	purine ribonucleotide catabolic process
2.21	1.46e-03	GO:0048858	cell projection morphogenesis
1.90	1.73e-03	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.55	1.75e-03	GO:0009056	catabolic process
2.30	2.20e-03	GO:0032446	protein modification by small protein conjugation
2.27	2.25e-03	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.99	2.25e-03	GO:0016044	cellular membrane organization
2.17	2.53e-03	GO:0032990	cell part morphogenesis
2.31	2.62e-03	GO:0072523	purine-containing compound catabolic process
1.98	2.63e-03	GO:0061024	membrane organization
2.31	2.90e-03	GO:0048812	neuron projection morphogenesis
2.21	3.34e-03	GO:0009141	nucleoside triphosphate metabolic process
1.55	3.43e-03	GO:0007399	nervous system development
2.31	3.81e-03	GO:0006195	purine nucleotide catabolic process
2.22	4.01e-03	GO:0009144	purine nucleoside triphosphate metabolic process
2.19	4.41e-03	GO:0034655	nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
2.19	4.41e-03	GO:0034656	nucleobase, nucleoside and nucleotide catabolic process
2.21	5.81e-03	GO:0009166	nucleotide catabolic process
2.29	6.76e-03	GO:0048667	cell morphogenesis involved in neuron differentiation
2.04	7.92e-03	GO:0016071	mRNA metabolic process
2.16	8.35e-03	GO:0006397	mRNA processing
2.16	8.35e-03	GO:0051603	proteolysis involved in cellular protein catabolic process
2.11	8.85e-03	GO:0044270	cellular nitrogen compound catabolic process
1.42	8.98e-03	GO:0006351	transcription, DNA-dependent
2.17	9.20e-03	GO:0019941	modification-dependent protein catabolic process
1.42	9.94e-03	GO:0032774	RNA biosynthetic process
2.16	1.10e-02	GO:0043632	modification-dependent macromolecule catabolic process
1.95	1.13e-02	GO:0072521	purine-containing compound metabolic process
2.26	1.19e-02	GO:0007017	microtubule-based process
2.12	1.30e-02	GO:0044257	cellular protein catabolic process
2.17	1.33e-02	GO:0006511	ubiquitin-dependent protein catabolic process
2.09	1.38e-02	GO:0046700	heterocycle catabolic process
1.99	1.60e-02	GO:0006163	purine nucleotide metabolic process
2.17	1.75e-02	GO:0007268	synaptic transmission
1.78	2.34e-02	GO:0006396	RNA processing
1.71	2.66e-02	GO:0046483	heterocycle metabolic process
4.32	2.76e-02	GO:0048489	synaptic vesicle transport
1.99	2.88e-02	GO:0019226	transmission of nerve impulse
1.99	2.88e-02	GO:0035637	multicellular organismal signaling
5.66	2.98e-02	GO:0010970	microtubule-based transport
5.66	2.98e-02	GO:0030705	cytoskeleton-dependent intracellular transport
2.75	3.16e-02	GO:0006184	GTP catabolic process
2.10	3.53e-02	GO:0008380	RNA splicing
15.10	4.56e-02	GO:0008090	retrograde axon cargo transport
4.87	4.57e-02	GO:0006888	ER to Golgi vesicle-mediated transport
2.07	4.93e-02	GO:0007264	small GTPase mediated signal transduction

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.36	3.10e-44	GO:0005622	intracellular
1.37	2.81e-43	GO:0044424	intracellular part
1.39	1.14e-34	GO:0043229	intracellular organelle
1.39	1.86e-34	GO:0043226	organelle
1.43	5.70e-34	GO:0005737	cytoplasm
1.41	1.60e-31	GO:0043227	membrane-bounded organelle
1.41	2.97e-31	GO:0043231	intracellular membrane-bounded organelle
1.44	5.27e-19	GO:0044444	cytoplasmic part
1.14	7.54e-17	GO:0005623	cell
1.14	7.54e-17	GO:0044464	cell part
1.43	1.43e-15	GO:0005634	nucleus
1.48	9.80e-15	GO:0044446	intracellular organelle part
1.47	2.69e-14	GO:0044422	organelle part
2.09	1.47e-09	GO:0031410	cytoplasmic vesicle
2.03	4.15e-09	GO:0031982	vesicle
1.43	4.99e-09	GO:0032991	macromolecular complex
3.37	1.87e-08	GO:0030135	coated vesicle
2.12	8.35e-08	GO:0043005	neuron projection
2.22	1.08e-07	GO:0045202	synapse
1.81	2.76e-07	GO:0005794	Golgi apparatus
2.11	3.31e-07	GO:0031988	membrane-bounded vesicle
1.63	3.81e-07	GO:0005829	cytosol
2.14	4.17e-07	GO:0016023	cytoplasmic membrane-bounded vesicle
1.43	4.54e-07	GO:0043234	protein complex
2.05	9.46e-07	GO:0015630	microtubule cytoskeleton
2.40	9.54e-07	GO:0044456	synapse part
2.56	3.31e-06	GO:0030424	axon
3.00	3.47e-05	GO:0030136	clathrin-coated vesicle
1.64	4.34e-05	GO:0042995	cell projection
1.48	5.08e-05	GO:0044428	nuclear part
1.74	9.92e-05	GO:0012505	endomembrane system
2.28	1.41e-04	GO:0030425	dendrite
1.57	1.43e-04	GO:0031090	organelle membrane
3.88	1.88e-04	GO:0030662	coated vesicle membrane
2.15	1.90e-04	GO:0044297	cell body
2.16	2.77e-04	GO:0043025	neuronal cell body
2.29	3.22e-04	GO:0005874	microtubule
5.73	4.85e-04	GO:0030120	vesicle coat
2.86	6.71e-04	GO:0033267	axon part
3.20	6.77e-04	GO:0008021	synaptic vesicle
1.95	9.39e-04	GO:0044463	cell projection part
2.61	1.09e-03	GO:0044433	cytoplasmic vesicle part
2.53	1.38e-03	GO:0012506	vesicle membrane
1.90	1.69e-03	GO:0005768	endosome
2.60	1.81e-03	GO:0030659	cytoplasmic vesicle membrane
2.09	3.17e-03	GO:0044431	Golgi apparatus part
6.71	3.60e-03	GO:0030658	transport vesicle membrane
1.50	3.62e-03	GO:0000267	cell fraction
2.26	3.97e-03	GO:0005815	microtubule organizing center
1.44	4.39e-03	GO:0031981	nuclear lumen
1.56	5.53e-03	GO:0044430	cytoskeletal part
5.23	1.10e-02	GO:0030660	Golgi-associated vesicle membrane
2.55	1.19e-02	GO:0019717	synaptosome
1.89	1.42e-02	GO:0005625	soluble fraction
1.30	2.02e-02	GO:0043228	non-membrane-bounded organelle
1.30	2.02e-02	GO:0043232	intracellular non-membrane-bounded organelle
2.48	2.80e-02	GO:0005681	spliceosomal complex
1.35	4.15e-02	GO:0070013	intracellular organelle lumen
2.31	4.30e-02	GO:0000139	Golgi membrane
2.88	4.53e-02	GO:0044306	neuron projection terminus
1.35	4.53e-02	GO:0043233	organelle lumen

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.38	2.67e-14	GO:0005515	protein binding
1.21	3.56e-14	GO:0005488	binding
1.53	6.79e-08	GO:0000166	nucleotide binding
1.51	1.37e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.50	2.62e-05	GO:0017076	purine nucleotide binding
1.49	3.27e-05	GO:0032555	purine ribonucleotide binding
1.49	3.40e-05	GO:0032553	ribonucleotide binding
1.74	6.41e-04	GO:0003723	RNA binding
1.73	2.39e-03	GO:0016462	pyrophosphatase activity
1.72	2.83e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.72	3.00e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
4.72	1.58e-02	GO:0019888	protein phosphatase regulator activity
1.42	1.94e-02	GO:0005524	ATP binding
1.66	2.02e-02	GO:0017111	nucleoside-triphosphatase activity
3.02	2.12e-02	GO:0031072	heat shock protein binding
1.92	2.16e-02	GO:0005525	GTP binding
1.40	2.39e-02	GO:0030554	adenyl nucleotide binding
1.40	2.90e-02	GO:0032559	adenyl ribonucleotide binding
2.09	2.93e-02	GO:0016791	phosphatase activity