• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: ATF6.p2

Z-value: 1.638

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_+_128519295	22.655		Kcnk1	potassium channel, subfamily K, member 1
chr6_+_4455686	21.974	NM_007743	Col1a2	collagen, type I, alpha 2
chr1_-_71699671	21.890	NM_010233	Fn1	fibronectin 1
chr7_-_52347489	19.419	NM_026555	Rcn3	reticulocalbin 3, EF-hand calcium binding domain
chr7_-_52347012	19.206		Rcn3	reticulocalbin 3, EF-hand calcium binding domain
chr12_+_110779204	19.002		Meg3	maternally expressed 3
chr5_+_144165615	18.313		Kdelr2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr15_+_79346819	17.731	NM_134090	Kdelr3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr4_-_11313886	17.029	NM_194055	Esrp1	epithelial splicing regulatory protein 1
chr8_+_128519001	16.113	NM_008430	Kcnk1	potassium channel, subfamily K, member 1
chr7_-_52722144	15.645	NM_007527	Bax	BCL2-associated X protein
chr5_+_144165482	15.598	NM_025841	Kdelr2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr6_-_101327849	15.437	NM_018884	Pdzrn3	PDZ domain containing RING finger 3
chr5_+_65361309	15.204	NM_026667	Fam114a1	family with sequence similarity 114, member A1
chr6_-_118429262	14.512		Zfp9	zinc finger protein 9
chr6_-_118429289	14.163	NM_011763	Zfp9	zinc finger protein 9
chr8_-_67171481	14.159		Cpe	carboxypeptidase E
chr14_+_55050437	13.789	NM_008608	Mmp14	matrix metallopeptidase 14 (membrane-inserted)
chr11_+_3414983	13.668		Selm	selenoprotein M
chr11_+_3414884	13.621		Selm	selenoprotein M
chr11_+_69778907	13.572	NM_016887	Cldn7	claudin 7
chr3_+_122970332	13.558	NM_027135	Sec24d	Sec24 related gene family, member D (S. cerevisiae)
chr8_-_67171805	13.533	NM_013494	Cpe	carboxypeptidase E
chr8_+_26830480	13.483	NM_028000	Ppapdc1b	phosphatidic acid phosphatase type 2 domain containing 1B
chr8_+_26830853	13.299		Ppapdc1b	phosphatidic acid phosphatase type 2 domain containing 1B
chr14_+_27457610	13.062	NM_007479	Arf4	ADP-ribosylation factor 4
chr11_+_3414792	12.504		Selm	selenoprotein M
chr11_+_87861245	12.380		Srsf1	serine/arginine-rich splicing factor 1
chr2_+_155207542	12.285		Trp53inp2	transformation related protein 53 inducible nuclear protein 2
chrX_+_78315963	12.123	NM_138751	Tmem47	transmembrane protein 47
chr13_-_38619746	12.088		Txndc5	thioredoxin domain containing 5
chr14_+_55050530	11.862		Mmp14	matrix metallopeptidase 14 (membrane-inserted)
chr13_-_38620109	11.672		Txndc5	thioredoxin domain containing 5
chr8_-_94325138	11.605	NM_008393	Irx3	Iroquois related homeobox 3 (Drosophila)
chrX_+_78316003	11.142		Tmem47	transmembrane protein 47
chr13_-_38620304	11.051		Txndc5	thioredoxin domain containing 5
chr1_-_75476031	10.970	NM_001001565 NM_001001566	Chpf	chondroitin polymerizing factor
chr8_-_67171692	10.850		Cpe	carboxypeptidase E
chr7_-_152125661	10.465		Ccnd1	cyclin D1
chr1_+_159436875	10.439	NM_033354	Sec16b	SEC16 homolog B (S. cerevisiae)
chr10_-_128360523	10.426	NM_015740	Bloc1s1	biogenesis of lysosome-related organelles complex-1, subunit 1
chrX_+_20447291	10.350	NM_001044384 NM_011593	Timp1	tissue inhibitor of metalloproteinase 1
chr14_-_66572577	10.346	NM_172604	Scara3	scavenger receptor class A, member 3
chr13_-_38620307	10.247	NM_145367	Txndc5	thioredoxin domain containing 5
chr7_+_135667279	9.830		Bag3	BCL2-associated athanogene 3
chr2_-_32143495	9.688	NM_175190	2900010J23Rik	RIKEN cDNA 2900010J23 gene
chr6_-_54543121	9.494	NM_153573	Fkbp14	FK506 binding protein 14
chr15_+_54402914	9.470	NM_178920	Mal2	mal, T-cell differentiation protein 2
chr11_+_69804871	9.376	NM_019749	Gabarap	gamma-aminobutyric acid receptor associated protein
chr2_+_155102040	9.322	NM_025735	Map1lc3a	microtubule-associated protein 1 light chain 3 alpha
chr12_-_86715324	9.230		Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)
chr17_+_45701100	9.205	NM_028662	Slc35b2	solute carrier family 35, member B2
chr11_+_53914425	9.122	NM_001136076 NM_011031	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
chr1_-_95342228	9.001		Hdlbp	high density lipoprotein (HDL) binding protein
chr4_+_80556574	8.902	NM_026821	D4Bwg0951e	DNA segment, Chr 4, Brigham & Women's Genetics 0951 expressed
chr6_-_54543167	8.764		Fkbp14	FK506 binding protein 14
chr10_-_127103595	8.551	NM_001122895 NM_008668	Nab2	Ngfi-A binding protein 2
chr8_+_13159279	8.533		Lamp1	lysosomal-associated membrane protein 1
chr11_+_78002569	8.454		Rab34	RAB34, member of RAS oncogene family
chr13_+_3537514	8.396		Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2
chr2_+_102390177	8.284	NM_173749	Pamr1	peptidase domain containing associated with muscle regeneration 1
chr11_+_96711152	8.083	NM_019877	Copz2	coatomer protein complex, subunit zeta 2
chr7_+_135667095	7.997	NM_013863	Bag3	BCL2-associated athanogene 3
chr3_-_58329346	7.972		Serp1	stress-associated endoplasmic reticulum protein 1
chrX_-_133275693	7.718	NM_001168225	Morf4l2	mortality factor 4 like 2
chr17_-_12962478	7.701	NM_010515	Igf2r	insulin-like growth factor 2 receptor
chr13_-_19487662	7.700		Stard3nl	STARD3 N-terminal like
chr10_-_83996632	7.688	NM_175451	Ckap4	cytoskeleton-associated protein 4
chr7_-_20334814	7.688		Pvrl2	poliovirus receptor-related 2
chr13_+_31898612	7.582		Foxc1	forkhead box C1
chr16_-_35490849	7.553	NM_028295	Pdia5	protein disulfide isomerase associated 5
chrX_-_133276147	7.545	NM_019768	Morf4l2	mortality factor 4 like 2
chr13_-_19487596	7.513	NM_024270	Stard3nl	STARD3 N-terminal like
chr5_+_143722032	7.453	NM_007984	Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chrX_+_71032347	7.452	NM_001166480	Ssr4	signal sequence receptor, delta
chr14_-_47006944	7.336		Bmp4	bone morphogenetic protein 4
chr7_-_149763980	7.328		H19	H19 fetal liver mRNA
chr17_-_29484429	7.312		Mtch1	mitochondrial carrier homolog 1 (C. elegans)
chr3_-_57379600	7.306	NM_133784	Wwtr1	WW domain containing transcription regulator 1
chrX_-_133275812	7.267	NM_001168226 NM_001168229	Morf4l2	mortality factor 4 like 2
chrX_+_71032398	7.207		Ssr4	signal sequence receptor, delta
chr15_+_99421458	7.200	NM_009701	Aqp5	aquaporin 5
chr15_+_54402988	7.173		Mal2	mal, T-cell differentiation protein 2
chr10_+_127759794	7.173		Cnpy2	canopy 2 homolog (zebrafish)
chr3_-_143868210	7.105	NM_010723	Lmo4	LIM domain only 4
chrX_+_53599573	7.083	NM_030139	Zfp449	zinc finger protein 449
chr10_-_94879435	7.072	NM_007706	Socs2	suppressor of cytokine signaling 2
chr12_+_30622876	7.066	NM_181395	Pxdn	peroxidasin homolog (Drosophila)
chr10_+_127759512	7.046	NM_019953	Cnpy2	canopy 2 homolog (zebrafish)
chr1_-_95375363	6.988		Hdlbp	high density lipoprotein (HDL) binding protein
chr12_-_58646914	6.967		Foxa1	forkhead box A1
chr7_-_6683113	6.937	NM_008817	Peg3	paternally expressed 3
chr3_-_143868114	6.896		Lmo4	LIM domain only 4
chr1_-_174012771	6.821	NM_021607	Ncstn	nicastrin
chr7_+_112788953	6.791		Fxc1	fractured callus expressed transcript 1
chr11_-_69734131	6.757	NM_001166590	Eif5a	eukaryotic translation initiation factor 5A
chr10_+_127759711	6.663		Cnpy2	canopy 2 homolog (zebrafish)
chrX_+_133200982	6.559		Tceal3	transcription elongation factor A (SII)-like 3
chr4_+_47487510	6.544	NM_024171	Sec61b	Sec61 beta subunit
chr11_+_29640992	6.492		Rtn4	reticulon 4
chr11_-_69734369	6.472	NM_001166592 NM_001166594	Eif5a	eukaryotic translation initiation factor 5A
chrX_+_133200913	6.442	NM_001029978	Tceal3	transcription elongation factor A (SII)-like 3
chr7_-_112781902	6.434	NM_018880	Trim3	tripartite motif-containing 3
chr19_-_60866516	6.431	NM_010123	Eif3a	eukaryotic translation initiation factor 3, subunit A
chr2_+_102390226	6.416		Pamr1	peptidase domain containing associated with muscle regeneration 1
chrX_-_132602648	6.414	NM_009749	Bex2	brain expressed X-linked 2
chr9_-_113617224	6.406	NM_001164677 NM_001164678 NM_011052	Pdcd6ip	programmed cell death 6 interacting protein
chr8_+_77617542	6.404		Hmox1	heme oxygenase (decycling) 1
chrX_+_131252456	6.401	NM_001166377 NM_001166378 NM_001166379 NM_001166380 NM_030066	Armcx1	armadillo repeat containing, X-linked 1
chr17_-_67703726	6.391	NM_008984	Ptprm	protein tyrosine phosphatase, receptor type, M
chrX_+_131252542	6.363		Armcx1	armadillo repeat containing, X-linked 1
chr2_+_132607398	6.359		Chgb	chromogranin B
chr1_-_95342168	6.356		Hdlbp	high density lipoprotein (HDL) binding protein
chr7_+_16683891	6.352	NM_025898	Napa	N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr12_+_34642516	6.308	NM_011658	Twist1	twist homolog 1 (Drosophila)
chr11_-_69734709	6.250	NM_001166595	Eif5a	eukaryotic translation initiation factor 5A
chr8_+_77617514	6.234	NM_010442	Hmox1	heme oxygenase (decycling) 1
chr1_-_75475845	6.218		Chpf	chondroitin polymerizing factor
chr2_-_71384748	6.217	NM_010054	Dlx2	distal-less homeobox 2
chr5_-_31247757	6.190	NM_001160149 NM_026770	Cgref1	cell growth regulator with EF hand domain 1
chr7_-_152125823	6.152	NM_007631	Ccnd1	cyclin D1
chrX_+_132779615	6.114	NM_011712	Wbp5	WW domain binding protein 5
chr9_-_91260619	6.077	NM_009573	Zic1	zinc finger protein of the cerebellum 1
chr10_-_94879369	6.042		Socs2	suppressor of cytokine signaling 2
chr17_-_25377052	6.027	NM_172529	Gnptg	N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr15_+_66723067	6.006		Wisp1	WNT1 inducible signaling pathway protein 1
chr2_+_132607408	5.983		Chgb	chromogranin B
chr17_+_45700882	5.940		Slc35b2	solute carrier family 35, member B2
chr19_+_45092581	5.939	NM_001130526	Lzts2	leucine zipper, putative tumor suppressor 2
chr8_-_107779002	5.934		B3gnt9-ps	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, pseudogene
chrX_-_131343508	5.928		Armcx2	armadillo repeat containing, X-linked 2
chr7_-_152125521	5.884		Ccnd1	cyclin D1
chr11_-_69734838	5.880	NM_001166589 NM_001166591 NM_181582	Eif5a	eukaryotic translation initiation factor 5A
chr3_-_58329639	5.863		Serp1	stress-associated endoplasmic reticulum protein 1
chr11_-_96777696	5.749	NM_030248	Cdk5rap3	CDK5 regulatory subunit associated protein 3
chr6_-_8728094	5.728		Ica1	islet cell autoantigen 1
chr6_+_116288073	5.711		March8	membrane-associated ring finger (C3HC4) 8
chr9_-_91260597	5.701		Zic1	zinc finger protein of the cerebellum 1
chr9_+_98464116	5.690	NM_015827	Copb2	coatomer protein complex, subunit beta 2 (beta prime)
chr2_-_173102033	5.629	NM_022995	Pmepa1	prostate transmembrane protein, androgen induced 1
chr10_+_125403274	5.612	NM_177152	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3
chr7_+_112788972	5.602		Fxc1	fractured callus expressed transcript 1
chr2_+_37307751	5.582	NM_001033960	Rabgap1	RAB GTPase activating protein 1
chr19_+_23215725	5.565		Klf9	Kruppel-like factor 9
chr7_-_112788821	5.531	NM_029802	Arfip2	ADP-ribosylation factor interacting protein 2
chr13_+_58909648	5.493		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr6_+_116288396	5.470		March8	membrane-associated ring finger (C3HC4) 8
chrX_+_149574498	5.462	NM_001004154	Rragb	Ras-related GTP binding B
chr10_-_127930880	5.453	NM_010860	Myl6	myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
chr3_+_131227699	5.448	NM_011863	Papss1	3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr1_-_95375372	5.433	NM_133808	Hdlbp	high density lipoprotein (HDL) binding protein
chr1_+_63319842	5.430	NM_028673	Zdbf2	zinc finger, DBF-type containing 2
chr5_-_136410216	5.426		Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr5_+_145016060	5.420	NM_018772	Bri3	brain protein I3
chr12_+_34642676	5.398		Twist1	twist homolog 1 (Drosophila)
chr13_+_58909236	5.386		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr8_+_108660959	5.361		1810019D21Rik	RIKEN cDNA 1810019D21 gene
chr10_-_83996516	5.352		Ckap4	cytoskeleton-associated protein 4
chr10_+_127759640	5.342		Cnpy2	canopy 2 homolog (zebrafish)
chr19_+_46227039	5.316	NM_178930	Gbf1	golgi-specific brefeldin A-resistance factor 1
chr15_-_81791230	5.292	NM_013872	Pmm1	phosphomannomutase 1
chr8_-_107779027	5.291	NM_178879	B3gnt9-ps	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, pseudogene
chr4_-_138648762	5.286	NM_008675	Nbl1	neuroblastoma, suppression of tumorigenicity 1
chr13_-_36826104	5.285		Nrn1	neuritin 1
chr11_+_120534337	5.284		Aspscr1	alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr11_-_100831909	5.281	NM_008986	Ptrf	polymerase I and transcript release factor
chr6_-_88468710	5.250	NM_016906	Sec61a1	Sec61 alpha 1 subunit (S. cerevisiae)
chr10_+_88194153	5.242	NM_025859	Arl1	ADP-ribosylation factor-like 1
chr2_+_18594027	5.235	NM_147778	Commd3	COMM domain containing 3
chr19_+_23215704	5.218	NM_010638	Klf9	Kruppel-like factor 9
chr2_+_152987262	5.188		Tm9sf4	transmembrane 9 superfamily protein member 4
chr11_-_116515361	5.180		Cygb	cytoglobin
chr6_-_124807704	5.169	NM_013534	Leprel2	leprecan-like 2
chr9_+_35018704	5.149	NM_026130	Srpr	signal recognition particle receptor ('docking protein')
chr2_+_37307786	5.141		Rabgap1	RAB GTPase activating protein 1
chr12_-_58647074	5.049	NM_008259	Foxa1	forkhead box A1
chr17_-_27076365	5.027	NM_026307 NM_026948	Cuta	cutA divalent cation tolerance homolog (E. coli)
chr11_-_51570335	5.007	NM_175255	Sec24a	Sec24 related gene family, member A (S. cerevisiae)
chr2_+_109757803	5.004	NM_172671	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4
chr1_-_82287990	4.985	NM_010570	Irs1	insulin receptor substrate 1
chr6_+_124881437	4.980		Mlf2	myeloid leukemia factor 2
chr13_-_36826245	4.930	NM_153529	Nrn1	neuritin 1
chr10_+_88194103	4.895		Arl1	ADP-ribosylation factor-like 1
chr10_-_36858671	4.862	NM_008538	Marcks	myristoylated alanine rich protein kinase C substrate
chr6_-_124807733	4.820		Leprel2	leprecan-like 2
chr6_+_124881376	4.819	NM_001170341 NM_145385	Mlf2	myeloid leukemia factor 2
chr6_+_28430311	4.814	NM_019776	Snd1	staphylococcal nuclease and tudor domain containing 1
chr10_+_90545834	4.804		Ikbip	IKBKB interacting protein
chr16_-_23890909	4.804	NM_009215	Sst	somatostatin
chr3_+_128916849	4.763	NM_001042502	Pitx2	paired-like homeodomain transcription factor 2
chr1_+_174012909	4.754		Copa	coatomer protein complex subunit alpha
chr2_-_156218547	4.751		2900097C17Rik	RIKEN cDNA 2900097C17 gene
chr4_-_47487233	4.745	NM_019998	Alg2	asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase)
chr2_+_132607432	4.717		Chgb	chromogranin B
chr6_-_39327637	4.717	NM_028123	Slc37a3	solute carrier family 37 (glycerol-3-phosphate transporter), member 3
chr16_-_44333103	4.713		Sidt1	SID1 transmembrane family, member 1
chr10_+_90545796	4.698		Ikbip	IKBKB interacting protein
chr16_+_20672847	4.686		Eif4g1	eukaryotic translation initiation factor 4, gamma 1
chr17_+_6106829	4.664	NM_001103181	Tulp4	tubby like protein 4
chr1_+_34364633	4.655		Dst	dystonin

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.62	1.09e-17	GO:0051641	cellular localization
2.62	1.63e-17	GO:0008104	protein localization
2.46	2.04e-17	GO:0033036	macromolecule localization
2.80	8.06e-16	GO:0015031	protein transport
2.68	2.31e-15	GO:0051649	establishment of localization in cell
2.73	3.63e-15	GO:0045184	establishment of protein localization
1.74	4.95e-15	GO:0051179	localization
2.98	2.28e-14	GO:0016192	vesicle-mediated transport
2.87	8.49e-13	GO:0046907	intracellular transport
5.93	8.63e-12	GO:0048193	Golgi vesicle transport
1.74	1.07e-11	GO:0006810	transport
1.72	2.74e-11	GO:0051234	establishment of localization
1.40	3.81e-11	GO:0044237	cellular metabolic process
2.90	1.74e-09	GO:0034613	cellular protein localization
2.88	2.30e-09	GO:0070727	cellular macromolecule localization
1.32	5.37e-09	GO:0008152	metabolic process
1.35	1.20e-08	GO:0044238	primary metabolic process
1.66	1.72e-08	GO:0048522	positive regulation of cellular process
1.65	6.77e-08	GO:0048731	system development
1.39	7.82e-08	GO:0043170	macromolecule metabolic process
1.42	7.83e-08	GO:0044260	cellular macromolecule metabolic process
1.99	1.28e-07	GO:0007399	nervous system development
1.53	1.54e-07	GO:0032502	developmental process
2.17	1.60e-07	GO:2000026	regulation of multicellular organismal development
1.49	4.42e-07	GO:0031323	regulation of cellular metabolic process
2.03	4.99e-07	GO:0050793	regulation of developmental process
1.56	7.63e-07	GO:0048518	positive regulation of biological process
1.44	1.03e-06	GO:0019222	regulation of metabolic process
1.56	1.61e-06	GO:0048856	anatomical structure development
2.88	2.46e-06	GO:0006886	intracellular protein transport
1.46	3.17e-06	GO:0080090	regulation of primary metabolic process
1.51	4.28e-06	GO:0007275	multicellular organismal development
1.52	8.98e-06	GO:0016043	cellular component organization
1.60	9.67e-06	GO:0044267	cellular protein metabolic process
15.13	1.25e-05	GO:0048199	vesicle targeting, to, from or within Golgi
12.02	2.28e-05	GO:0006901	vesicle coating
1.52	2.46e-05	GO:0019538	protein metabolic process
1.44	2.62e-05	GO:0060255	regulation of macromolecule metabolic process
1.59	2.65e-05	GO:0048523	negative regulation of cellular process
1.54	6.34e-05	GO:0048519	negative regulation of biological process
15.89	7.24e-05	GO:0048200	Golgi transport vesicle coating
15.89	7.24e-05	GO:0048205	COPI coating of Golgi vesicle
1.47	8.35e-05	GO:0071840	cellular component organization or biogenesis
1.15	9.38e-05	GO:0009987	cellular process
2.43	1.14e-04	GO:0061024	membrane organization
1.74	1.20e-04	GO:0009653	anatomical structure morphogenesis
10.21	1.40e-04	GO:0006900	membrane budding
14.44	1.91e-04	GO:0048194	Golgi vesicle budding
2.24	1.97e-04	GO:0051094	positive regulation of developmental process
2.00	2.42e-04	GO:0048699	generation of neurons
1.96	2.50e-04	GO:0022008	neurogenesis
2.39	2.71e-04	GO:0016044	cellular membrane organization
1.68	2.78e-04	GO:0051239	regulation of multicellular organismal process
1.97	3.96e-04	GO:0045595	regulation of cell differentiation
1.68	4.25e-04	GO:0023051	regulation of signaling
1.60	5.02e-04	GO:0048513	organ development
2.55	6.01e-04	GO:0035295	tube development
2.72	6.20e-04	GO:0031329	regulation of cellular catabolic process
10.09	8.74e-04	GO:0006903	vesicle targeting
1.65	9.70e-04	GO:0065009	regulation of molecular function
1.83	1.04e-03	GO:0032268	regulation of cellular protein metabolic process
1.44	1.26e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
6.40	1.32e-03	GO:0051648	vesicle localization
2.33	1.32e-03	GO:0060284	regulation of cell development
2.50	1.37e-03	GO:0009894	regulation of catabolic process
5.27	1.51e-03	GO:0045666	positive regulation of neuron differentiation
1.44	1.51e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.46	1.58e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.44	1.73e-03	GO:0010468	regulation of gene expression
1.52	2.36e-03	GO:0048869	cellular developmental process
1.53	2.37e-03	GO:0030154	cell differentiation
2.61	2.42e-03	GO:0007264	small GTPase mediated signal transduction
1.39	2.76e-03	GO:0009058	biosynthetic process
2.14	3.13e-03	GO:0043009	chordate embryonic development
3.68	3.53e-03	GO:0021915	neural tube development
2.33	3.75e-03	GO:0051960	regulation of nervous system development
1.43	4.24e-03	GO:0010556	regulation of macromolecule biosynthetic process
2.11	4.63e-03	GO:0009792	embryo development ending in birth or egg hatching
1.38	5.52e-03	GO:0044249	cellular biosynthetic process
2.54	6.06e-03	GO:0045664	regulation of neuron differentiation
6.13	6.63e-03	GO:0034976	response to endoplasmic reticulum stress
1.71	6.85e-03	GO:0010646	regulation of cell communication
1.71	8.34e-03	GO:0051246	regulation of protein metabolic process
1.82	8.37e-03	GO:0009790	embryo development
1.72	8.60e-03	GO:0010941	regulation of cell death
9.35	8.94e-03	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
1.73	9.87e-03	GO:0010605	negative regulation of macromolecule metabolic process
6.59	1.08e-02	GO:0006888	ER to Golgi vesicle-mediated transport
11.35	1.14e-02	GO:0006891	intra-Golgi vesicle-mediated transport
1.69	1.28e-02	GO:0009892	negative regulation of metabolic process
1.54	1.31e-02	GO:0006464	protein modification process
2.32	1.44e-02	GO:0050767	regulation of neurogenesis
1.64	1.50e-02	GO:0050790	regulation of catalytic activity
1.39	1.53e-02	GO:0009889	regulation of biosynthetic process
2.62	1.55e-02	GO:0035239	tube morphogenesis
7.26	1.64e-02	GO:0051650	establishment of vesicle localization
1.42	1.67e-02	GO:0009059	macromolecule biosynthetic process
2.02	1.71e-02	GO:0072358	cardiovascular system development
2.02	1.71e-02	GO:0072359	circulatory system development
1.39	1.75e-02	GO:0031326	regulation of cellular biosynthetic process
1.43	1.76e-02	GO:0051252	regulation of RNA metabolic process
1.50	2.12e-02	GO:0065008	regulation of biological quality
1.60	2.14e-02	GO:0010604	positive regulation of macromolecule metabolic process
2.93	2.20e-02	GO:0060537	muscle tissue development
1.86	2.36e-02	GO:0010629	negative regulation of gene expression
1.50	2.39e-02	GO:0043412	macromolecule modification
1.42	2.44e-02	GO:0006355	regulation of transcription, DNA-dependent
1.74	2.51e-02	GO:0009888	tissue development
4.16	2.51e-02	GO:0001841	neural tube formation
1.41	2.62e-02	GO:0034645	cellular macromolecule biosynthetic process
1.82	2.99e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.69	3.01e-02	GO:0031324	negative regulation of cellular metabolic process
1.83	3.93e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.39	3.96e-02	GO:0010467	gene expression
1.85	4.18e-02	GO:0033554	cellular response to stress
1.87	4.22e-02	GO:0009887	organ morphogenesis
2.12	4.26e-02	GO:0045597	positive regulation of cell differentiation
1.57	4.30e-02	GO:0031325	positive regulation of cellular metabolic process
1.74	4.58e-02	GO:0051128	regulation of cellular component organization
1.43	4.76e-02	GO:0071842	cellular component organization at cellular level

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.62	3.83e-45	GO:0005737	cytoplasm
1.42	1.09e-37	GO:0044424	intracellular part
1.41	2.19e-37	GO:0005622	intracellular
1.74	7.52e-34	GO:0044444	cytoplasmic part
1.40	1.70e-23	GO:0043226	organelle
1.39	3.24e-23	GO:0043229	intracellular organelle
1.43	2.12e-22	GO:0043227	membrane-bounded organelle
1.43	2.56e-22	GO:0043231	intracellular membrane-bounded organelle
1.18	4.19e-18	GO:0005623	cell
1.18	4.19e-18	GO:0044464	cell part
2.44	1.48e-15	GO:0005783	endoplasmic reticulum
1.98	4.79e-11	GO:0005829	cytosol
2.08	4.52e-08	GO:0005794	Golgi apparatus
3.06	1.65e-07	GO:0044431	Golgi apparatus part
1.39	7.07e-06	GO:0044446	intracellular organelle part
1.37	1.57e-05	GO:0044422	organelle part
1.99	2.09e-05	GO:0012505	endomembrane system
3.28	9.93e-05	GO:0030135	coated vesicle
1.94	1.29e-04	GO:0031982	vesicle
3.33	1.37e-04	GO:0000139	Golgi membrane
1.93	3.48e-04	GO:0031410	cytoplasmic vesicle
1.29	3.87e-04	GO:0005634	nucleus
2.51	3.93e-04	GO:0048471	perinuclear region of cytoplasm
10.59	5.04e-04	GO:0030137	COPI-coated vesicle
5.67	7.80e-04	GO:0005798	Golgi-associated vesicle
1.66	8.91e-04	GO:0031090	organelle membrane
7.04	9.20e-04	GO:0030120	vesicle coat
1.36	1.29e-03	GO:0032991	macromolecular complex
2.01	1.50e-03	GO:0031988	membrane-bounded vesicle
11.35	1.80e-03	GO:0030663	COPI coated vesicle membrane
2.04	1.81e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
4.22	3.37e-03	GO:0030662	coated vesicle membrane
1.62	4.52e-03	GO:0000267	cell fraction
1.71	4.75e-03	GO:0005626	insoluble fraction
4.39	4.75e-03	GO:0030117	membrane coat
4.39	4.75e-03	GO:0048475	coated membrane
1.37	6.30e-03	GO:0043234	protein complex
2.89	6.62e-03	GO:0030659	cytoplasmic vesicle membrane
2.76	8.67e-03	GO:0012506	vesicle membrane
2.80	1.05e-02	GO:0044433	cytoplasmic vesicle part
2.01	1.25e-02	GO:0005768	endosome
15.13	1.78e-02	GO:0000421	autophagic vacuole membrane
10.32	2.06e-02	GO:0030126	COPI vesicle coat
1.65	2.50e-02	GO:0005624	membrane fraction
6.11	3.37e-02	GO:0030660	Golgi-associated vesicle membrane
1.80	4.35e-02	GO:0043005	neuron projection

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.46	1.99e-13	GO:0005515	protein binding
1.25	9.03e-13	GO:0005488	binding
2.30	1.04e-05	GO:0019904	protein domain specific binding
1.90	1.03e-04	GO:0019899	enzyme binding
1.97	2.15e-04	GO:0046983	protein dimerization activity
1.87	6.20e-04	GO:0042802	identical protein binding
1.76	2.08e-03	GO:0030528	transcription regulator activity
2.53	3.05e-03	GO:0019901	protein kinase binding
2.24	3.50e-03	GO:0032403	protein complex binding
2.27	5.01e-03	GO:0005525	GTP binding
3.66	6.07e-03	GO:0008135	translation factor activity, nucleic acid binding
12.61	8.51e-03	GO:0019789	SUMO ligase activity
2.65	9.65e-03	GO:0019787	small conjugating protein ligase activity
2.17	1.32e-02	GO:0019001	guanyl nucleotide binding
2.17	1.32e-02	GO:0032561	guanyl ribonucleotide binding
2.86	1.77e-02	GO:0003924	GTPase activity
5.24	1.84e-02	GO:0005097	Rab GTPase activator activity
2.44	2.45e-02	GO:0016881	acid-amino acid ligase activity
2.19	3.13e-02	GO:0019900	kinase binding
3.51	3.54e-02	GO:0005099	Ras GTPase activator activity
1.71	3.90e-02	GO:0001071	nucleic acid binding transcription factor activity
1.71	3.90e-02	GO:0003700	sequence-specific DNA binding transcription factor activity
22.70	4.07e-02	GO:0046923	ER retention sequence binding
1.91	4.35e-02	GO:0042803	protein homodimerization activity