Motif ID: CREB1.p2

Z-value: 1.247


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
Creb1 12912 cAMP responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1chr1_+_645795590.425.1e-09Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_13338741 14.173 Tfdp1
transcription factor Dp 1
chr18_+_11815869 13.941 Rbbp8
retinoblastoma binding protein 8
chr3_-_19211000 13.566 NM_001122759
Pde7a
phosphodiesterase 7A
chr6_-_88848650 13.365 NM_008564
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr7_-_31449991 12.848 NM_027999
Haus5
HAUS augmin-like complex, subunit 5
chr2_+_35992148 11.968 Mrrf
mitochondrial ribosome recycling factor
chr19_-_4625574 11.356 NM_023131
Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr19_-_4625276 10.949 Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr3_-_36470904 10.712 NM_009828
Ccna2
cyclin A2
chr11_-_76057153 10.355 Glod4
glyoxalase domain containing 4
chr3_-_36470845 10.174 Ccna2
cyclin A2
chr7_-_31449951 9.936 Haus5
HAUS augmin-like complex, subunit 5
chr4_-_133801438 9.781 NM_024215
Zfp593
zinc finger protein 593
chr12_+_113883038 9.407 NM_001161737
NM_013929
Siva1

SIVA1, apoptosis-inducing factor

chr3_+_134875526 9.305 NM_173762
Cenpe
centromere protein E
chr3_-_36470882 9.104 Ccna2
cyclin A2
chr9_-_64020685 8.860 NM_026507
Zwilch
Zwilch, kinetochore associated, homolog (Drosophila)
chr17_-_71660199 8.766 NM_145158
Emilin2
elastin microfibril interfacer 2
chr15_+_100058249 8.750 NM_007497
Atf1
activating transcription factor 1
chr11_-_76057188 8.630 NM_026029
Glod4
glyoxalase domain containing 4
chr3_-_127256215 8.611 NM_138593
Larp7
La ribonucleoprotein domain family, member 7
chr6_-_82724366 8.295 NM_013820
Hk2
hexokinase 2
chr19_+_59335367 8.290 NM_172523
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr2_+_118938549 8.271 NM_011234
Rad51
RAD51 homolog (S. cerevisiae)
chr2_-_126959605 8.207 NM_144818
Ncaph
non-SMC condensin I complex, subunit H
chr12_+_117519658 7.985 NM_028731
Esyt2
extended synaptotagmin-like protein 2
chr3_+_30993952 7.876 NM_001039090
NM_011386
Skil

SKI-like

chr14_+_79880952 7.811 NM_007920
Elf1
E74-like factor 1
chr11_-_62094853 7.736 NM_027198
Zswim7
zinc finger, SWIM-type containing 7
chr19_+_6085096 7.474 NM_026410
Cdca5
cell division cycle associated 5
chr17_-_71876127 7.455 Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr7_+_109590208 7.453 NM_009103
Rrm1
ribonucleotide reductase M1
chr15_+_81846798 7.451 NM_010247
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr15_+_79177959 7.449 Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr6_-_131243197 7.400 NM_025564
Magohb
mago-nashi homolog B (Drosophila)
chr17_-_71876150 7.295 NM_023294
Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr14_-_47896531 7.270 NM_172598
Wdhd1
WD repeat and HMG-box DNA binding protein 1
chr15_-_81229961 7.243 St13
suppression of tumorigenicity 13
chr2_+_109120894 7.221 NM_139303
Kif18a
kinesin family member 18A
chr11_+_76057230 7.203 NM_183263
Rnmtl1
RNA methyltransferase like 1
chr10_-_6373388 7.043 NM_001170785
NM_001170786
NM_172308
Mthfd1l


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr15_+_100058310 6.947 Atf1
activating transcription factor 1
chr15_+_79178063 6.898 NM_010755
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr8_+_125000042 6.819 NM_153775
Ctu2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr2_+_167514414 6.738 NM_009883
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr16_-_4077714 6.673 NM_026508
Trap1
TNF receptor-associated protein 1
chr3_+_40603872 6.558 NM_011495
Plk4
polo-like kinase 4 (Drosophila)
chr6_-_127100954 6.541 NM_009829
Ccnd2
cyclin D2
chr7_-_52781502 6.449 NM_008654
Ppp1r15a
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr10_-_6373309 6.402 Mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr9_-_107192203 6.355 NM_178907
Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr14_-_31832165 6.354 Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr3_+_67178037 6.319 Mlf1
myeloid leukemia factor 1
chr5_-_111082387 6.310 NM_153570
Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)
chr11_-_102046532 6.284 NM_172947
Lsm12
LSM12 homolog (S. cerevisiae)
chr8_-_87186691 6.279 NM_010499
Ier2
immediate early response 2
chr17_-_41071432 6.204 NM_031863
Cenpq
centromere protein Q
chr8_-_83263323 6.131 NM_053124
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr17_+_23816331 6.130 NM_018777
Cldn6
claudin 6
chr7_+_119822831 6.061 NM_001166584
NM_009346
Tead1

TEA domain family member 1

chr9_-_20781206 6.041 NM_010333
S1pr2
sphingosine-1-phosphate receptor 2
chr9_+_14589080 6.023 Mre11a
meiotic recombination 11 homolog A (S. cerevisiae)
chr9_-_59334393 5.960 Arih1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr14_+_64479167 5.945 Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr14_-_31832274 5.933 NM_153547
Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr9_-_20781133 5.921 S1pr2
sphingosine-1-phosphate receptor 2
chr3_+_67178016 5.902 NM_001039543
NM_010801
Mlf1

myeloid leukemia factor 1

chr3_+_79433000 5.894 NM_029482
4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr10_-_92185071 5.841 NM_008682
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr9_+_14589122 5.829 NM_018736
Mre11a
meiotic recombination 11 homolog A (S. cerevisiae)
chr3_+_90052083 5.804 NM_013901
Slc39a1
solute carrier family 39 (zinc transporter), member 1
chr9_-_59334089 5.780 NM_019927
Arih1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr3_+_98944990 5.724 NM_027462
Wars2
tryptophanyl tRNA synthetase 2 (mitochondrial)
chr8_-_124999921 5.720 NM_001033142
Rnf166
ring finger protein 166
chr4_-_55545337 5.682 NM_010637
Klf4
Kruppel-like factor 4 (gut)
chr10_+_85334563 5.678 NM_133993
Pwp1
PWP1 homolog (S. cerevisiae)
chr2_+_167514460 5.594 Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr6_-_87788752 5.555 NM_133934
Isy1
ISY1 splicing factor homolog (S. cerevisiae)
chr1_-_158404299 5.514 NM_009230
Soat1
sterol O-acyltransferase 1
chr9_-_107191674 5.488 Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr4_-_123427465 5.481 NM_023423
Akirin1
akirin 1
chr5_-_112772024 5.469 NM_027323
Srrd
SRR1 domain containing
chr14_-_47809063 5.442 NM_008102
Gch1
GTP cyclohydrolase 1
chr12_+_113858217 5.410 NM_007421
Adssl1
adenylosuccinate synthetase like 1
chr15_+_81230560 5.247 NM_177310
Xpnpep3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr3_-_127256181 5.214 Larp7
La ribonucleoprotein domain family, member 7
chr15_+_61869529 5.208 Pvt1
plasmacytoma variant translocation 1
chr18_+_11816327 5.197 NM_001081223
Rbbp8
retinoblastoma binding protein 8
chr7_-_151739579 5.190 NM_001033319
NM_001195086
Ppfia1

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1

chr11_+_69794546 5.160 NM_026017
Ctdnep1
CTD nuclear envelope phosphatase 1
chr19_-_40662819 5.154 NM_019698
NM_153554
Aldh18a1

aldehyde dehydrogenase 18 family, member A1

chr7_-_87547589 5.051 NM_011046
Furin
furin (paired basic amino acid cleaving enzyme)
chr7_-_26035683 5.013 NM_010155
Erf
Ets2 repressor factor
chr6_-_87788729 4.986 Isy1
ISY1 splicing factor homolog (S. cerevisiae)
chr16_+_14361637 4.981 NM_008576
Abcc1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr19_+_18745215 4.966 NM_026120
2410127L17Rik
RIKEN cDNA 2410127L17 gene
chr8_-_83262881 4.948 Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chrX_+_97821403 4.945 NM_008446
Kif4
kinesin family member 4
chr3_+_127256406 4.925 NM_197997
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr5_+_123157541 4.876 NM_011026
P2rx4
purinergic receptor P2X, ligand-gated ion channel 4
chr7_-_127039189 4.859 NM_001163703
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr18_-_46685512 4.839 Fem1c
fem-1 homolog c (C.elegans)
chr3_-_127256114 4.805 Larp7
La ribonucleoprotein domain family, member 7
chr12_-_112217151 4.790 NM_175207
Ankrd9
ankyrin repeat domain 9
chr1_-_51535232 4.782 NM_028696
Obfc2a
oligonucleotide/oligosaccharide-binding fold containing 2A
chr6_+_100783598 4.774 NM_182939
Ppp4r2
protein phosphatase 4, regulatory subunit 2
chr10_-_83996632 4.772 NM_175451
Ckap4
cytoskeleton-associated protein 4
chr6_-_37391993 4.764 NM_178661
Creb3l2
cAMP responsive element binding protein 3-like 2
chr18_-_67884185 4.714 NM_001127177
NM_008977
Ptpn2

protein tyrosine phosphatase, non-receptor type 2

chrX_+_70962097 4.684 Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr14_-_47896464 4.655 Wdhd1
WD repeat and HMG-box DNA binding protein 1
chr5_-_111082269 4.644 Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)
chr1_-_52557130 4.627 NM_008667
Nab1
Ngfi-A binding protein 1
chr10_-_127962914 4.625 NM_011843
Esyt1
extended synaptotagmin-like protein 1
chr12_-_74387687 4.622 NM_029580
Trmt5
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr2_+_35991917 4.585 NM_026422
Mrrf
mitochondrial ribosome recycling factor
chrX_+_70962057 4.576 Abcd1
ATP-binding cassette, sub-family D (ALD), member 1
chr10_-_127613623 4.575 NM_019711
Rbms2
RNA binding motif, single stranded interacting protein 2
chr7_+_109358966 4.561 Pgap2
post-GPI attachment to proteins 2
chr8_-_82235601 4.554 NM_015751
Abce1
ATP-binding cassette, sub-family E (OABP), member 1
chrX_-_91368427 4.546 Zfx
zinc finger protein X-linked
chr19_+_43764161 4.535 NM_053103
Entpd7
ectonucleoside triphosphate diphosphohydrolase 7
chr2_-_25221101 4.526 NM_001033293
Uap1l1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr6_+_140572056 4.508 NM_001005605
Aebp2
AE binding protein 2
chr11_-_69734838 4.499 NM_001166589
NM_001166591
NM_181582
Eif5a


eukaryotic translation initiation factor 5A


chr4_+_151413427 4.497 NM_001159599
NM_028727
Nol9

nucleolar protein 9

chr4_-_150432002 4.471 NM_009498
Vamp3
vesicle-associated membrane protein 3
chr15_-_27560282 4.460 NM_001013792
Fam105b
family with sequence similarity 105, member B
chr16_+_57549340 4.446 NM_001177871
Filip1l
filamin A interacting protein 1-like
chr2_-_119980243 4.433 NM_133838
Ehd4
EH-domain containing 4
chr10_-_29920326 4.429 NM_001109747
Cenpw
centromere protein W
chr2_-_132078887 4.409 NM_011045
Pcna
proliferating cell nuclear antigen
chr8_+_74659107 4.393 NM_001001491
Tpm4
tropomyosin 4
chr2_+_32631305 4.355 NM_178595
Ptrh1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr10_-_83996516 4.341 Ckap4
cytoskeleton-associated protein 4
chr14_-_87540920 4.297 NM_019670
Diap3
diaphanous homolog 3 (Drosophila)
chr8_-_108535317 4.286 NM_028038
Ddx28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr9_-_85220730 4.283 NM_001160378
NM_001160379
Fam46a

family with sequence similarity 46, member A

chr2_-_119980210 4.270 Ehd4
EH-domain containing 4
chr19_+_7568529 4.263 NM_001163505
Atl3
atlastin GTPase 3
chr8_+_108424267 4.196 NM_173432
Pskh1
protein serine kinase H1
chr17_-_26206487 4.181 Rab11fip3
RAB11 family interacting protein 3 (class II)
chr9_+_113650560 4.130 NM_001114347
Clasp2
CLIP associating protein 2
chr8_+_77633426 4.097 NM_008566
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr10_-_53795556 4.096 NM_008548
Man1a
mannosidase 1, alpha
chr1_+_52065469 4.083 Stat4
signal transducer and activator of transcription 4
chr11_-_86621130 4.081 NM_026191
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr19_+_37450854 4.051 NM_010615
Kif11
kinesin family member 11
chr15_-_81230036 4.050 NM_133726
St13
suppression of tumorigenicity 13
chr7_+_16894925 4.029 NM_133234
Bbc3
BCL2 binding component 3
chr11_-_69734709 4.001 NM_001166595
Eif5a
eukaryotic translation initiation factor 5A
chr2_+_164571458 4.001 NM_133763
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr7_+_31338319 3.998 NM_001012401
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr17_+_15841889 3.976 NM_007690
Chd1
chromodomain helicase DNA binding protein 1
chr5_+_76569257 3.968 NM_020611
Srd5a3
steroid 5 alpha-reductase 3
chr8_+_41597112 3.955 NM_033560
Vps37a
vacuolar protein sorting 37A (yeast)
chr13_-_46823191 3.946 NM_175749
Nup153
nucleoporin 153
chr12_+_111976121 3.931 NM_027149
Wdr20a
WD repeat domain 20A
chr19_+_5637712 3.930 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr13_+_73397944 3.929 NM_018885
Irx4
Iroquois related homeobox 4 (Drosophila)
chr1_+_95375503 3.918 NM_001159717
NM_001159718
NM_010891
NM_001159719
Sept2



septin 2



chr12_+_110031153 3.900 Yy1
YY1 transcription factor
chr8_+_34842304 3.898 NM_001167921
Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr10_+_51742333 3.891 Vgll2
vestigial like 2 homolog (Drosophila)
chr5_-_138227888 3.871 NM_144913
Mepce
methylphosphate capping enzyme
chr13_+_73398198 3.871 Irx4
Iroquois related homeobox 4 (Drosophila)
chr6_+_140572347 3.855 Aebp2
AE binding protein 2
chr10_+_126478969 3.830 NM_010792
Mettl1
methyltransferase like 1
chr2_-_76511070 3.818 NM_010222
Fkbp7
FK506 binding protein 7
chr19_+_5637741 3.786 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr2_+_125684938 3.779 NM_175154
Galk2
galactokinase 2
chr8_+_108535363 3.775 NM_025518
Dus2l
dihydrouridine synthase 2-like (SMM1, S. cerevisiae)
chr2_+_25110946 3.766 NM_177344
Tmem203
transmembrane protein 203
chr11_-_115992196 3.761 NM_178802
Trim65
tripartite motif-containing 65
chr11_+_120810346 3.736 NM_001038653
NM_001038654
Slc16a3

solute carrier family 16 (monocarboxylic acid transporters), member 3

chr15_+_34012606 3.726 Mtdh
metadherin
chr2_+_31829969 3.719 NM_172268
Nup214
nucleoporin 214
chrX_-_138825032 3.715 NM_001033600
NM_019477
NM_207625
Acsl4


acyl-CoA synthetase long-chain family member 4


chr3_-_8923789 3.705 NM_025434
Mrps28
mitochondrial ribosomal protein S28
chr9_+_48303449 3.702 NM_001004191
Gm5617
predicted gene 5617
chr8_-_72498125 3.702 Gatad2a
GATA zinc finger domain containing 2A
chr1_+_82313139 3.699 NM_029777
Rhbdd1
rhomboid domain containing 1
chr7_+_54101157 3.693 NM_010699
Ldha
lactate dehydrogenase A
chr19_-_34549624 3.693 NM_009890
Ch25h
cholesterol 25-hydroxylase
chr8_-_107155195 3.681 NM_019662
Rrad
Ras-related associated with diabetes
chr2_-_103601232 3.676 NM_153126
Nat10
N-acetyltransferase 10
chr9_+_108462759 3.662 NM_011830
Impdh2
inosine 5'-phosphate dehydrogenase 2
chr10_+_110910277 3.654 Nap1l1
nucleosome assembly protein 1-like 1
chr17_+_35118956 3.632 NM_030597
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr9_+_107951572 3.591 NM_177910
Gmppb
GDP-mannose pyrophosphorylase B
chr11_+_53164267 3.590 NM_033565
Aff4
AF4/FMR2 family, member 4
chr14_+_64479129 3.566 NM_028228
Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr17_+_34987323 3.563 NM_001045863
NM_001045864
NM_138580
Rdbp


RD RNA-binding protein


chr14_-_32064403 3.546 NM_027949
Phf7
PHD finger protein 7
chr5_+_48763568 3.544 NM_025755
Pacrgl
PARK2 co-regulated-like
chr18_+_66618186 3.526 NM_021451
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr7_-_31514527 3.520 NM_027215
Tmem147
transmembrane protein 147
chr15_-_59205688 3.518 NM_153548
E430025E21Rik
RIKEN cDNA E430025E21 gene
chrX_-_35917684 3.516 Cul4b
cullin 4B
chr1_-_97564064 3.510 St8sia4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.77 7.10e-41 GO:0044260 cellular macromolecule metabolic process
1.58 2.96e-36 GO:0044237 cellular metabolic process
1.66 1.15e-34 GO:0043170 macromolecule metabolic process
1.91 1.54e-34 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.02 1.75e-34 GO:0090304 nucleic acid metabolic process
1.54 5.63e-33 GO:0044238 primary metabolic process
1.83 7.87e-33 GO:0034641 cellular nitrogen compound metabolic process
1.80 1.02e-31 GO:0006807 nitrogen compound metabolic process
2.01 2.09e-31 GO:0010467 gene expression
1.44 1.65e-27 GO:0008152 metabolic process
1.96 1.50e-25 GO:0016070 RNA metabolic process
1.92 1.17e-24 GO:0009059 macromolecule biosynthetic process
1.79 1.46e-24 GO:0044249 cellular biosynthetic process
1.92 1.66e-24 GO:0034645 cellular macromolecule biosynthetic process
1.75 2.97e-23 GO:0009058 biosynthetic process
1.63 5.76e-19 GO:0031323 regulation of cellular metabolic process
1.62 2.51e-17 GO:0060255 regulation of macromolecule metabolic process
1.60 3.55e-17 GO:0080090 regulation of primary metabolic process
1.54 1.95e-16 GO:0019222 regulation of metabolic process
1.73 2.95e-16 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.69 4.17e-16 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.68 8.94e-16 GO:0051171 regulation of nitrogen compound metabolic process
1.75 1.21e-15 GO:0051252 regulation of RNA metabolic process
1.70 2.02e-15 GO:0010556 regulation of macromolecule biosynthetic process
1.88 3.44e-15 GO:0006351 transcription, DNA-dependent
1.88 4.19e-15 GO:0032774 RNA biosynthetic process
1.73 1.45e-14 GO:0006355 regulation of transcription, DNA-dependent
1.64 4.26e-14 GO:0009889 regulation of biosynthetic process
1.65 5.73e-14 GO:0031326 regulation of cellular biosynthetic process
1.65 6.56e-14 GO:0010468 regulation of gene expression
1.56 1.51e-11 GO:0071840 cellular component organization or biogenesis
1.66 2.29e-11 GO:0071841 cellular component organization or biogenesis at cellular level
1.85 6.21e-11 GO:0006996 organelle organization
2.45 3.03e-09 GO:0006259 DNA metabolic process
1.16 1.26e-08 GO:0009987 cellular process
1.50 2.18e-08 GO:0016043 cellular component organization
1.56 7.69e-08 GO:0044267 cellular protein metabolic process
2.02 7.86e-08 GO:0007049 cell cycle
1.58 9.87e-08 GO:0071842 cellular component organization at cellular level
2.24 2.96e-07 GO:0006396 RNA processing
2.21 2.47e-06 GO:0051276 chromosome organization
2.29 5.41e-06 GO:0022403 cell cycle phase
1.46 8.98e-06 GO:0048522 positive regulation of cellular process
3.24 1.24e-05 GO:0006260 DNA replication
1.98 1.85e-05 GO:0033554 cellular response to stress
2.28 2.10e-05 GO:0006974 response to DNA damage stimulus
1.42 2.50e-05 GO:0048518 positive regulation of biological process
2.00 3.17e-05 GO:0046907 intracellular transport
1.82 4.82e-05 GO:0051649 establishment of localization in cell
1.67 5.33e-05 GO:0033036 macromolecule localization
2.11 1.38e-04 GO:0051726 regulation of cell cycle
1.97 1.54e-04 GO:0022402 cell cycle process
1.71 1.66e-04 GO:0051641 cellular localization
1.39 2.99e-04 GO:0019538 protein metabolic process
3.97 4.06e-04 GO:0050657 nucleic acid transport
3.97 4.06e-04 GO:0050658 RNA transport
3.97 4.06e-04 GO:0051236 establishment of RNA localization
1.89 4.08e-04 GO:0012501 programmed cell death
1.84 4.72e-04 GO:0016265 death
2.26 4.73e-04 GO:0051301 cell division
3.82 7.75e-04 GO:0006403 RNA localization
1.87 8.92e-04 GO:0006915 apoptosis
2.32 9.95e-04 GO:0006281 DNA repair
2.12 1.31e-03 GO:0000278 mitotic cell cycle
2.18 1.70e-03 GO:0000279 M phase
3.38 1.72e-03 GO:0051329 interphase of mitotic cell cycle
1.78 2.55e-03 GO:0008219 cell death
1.72 2.68e-03 GO:0045184 establishment of protein localization
3.28 2.88e-03 GO:0051325 interphase
2.27 3.27e-03 GO:0006412 translation
2.46 3.71e-03 GO:0010564 regulation of cell cycle process
2.58 5.97e-03 GO:0034470 ncRNA processing
3.36 6.32e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.61 7.30e-03 GO:0008104 protein localization
1.70 7.49e-03 GO:0015031 protein transport
2.53 8.36e-03 GO:0022613 ribonucleoprotein complex biogenesis
2.08 8.49e-03 GO:0016071 mRNA metabolic process
1.44 8.74e-03 GO:0043412 macromolecule modification
3.73 9.17e-03 GO:0051028 mRNA transport
2.02 1.05e-02 GO:0006325 chromatin organization
2.34 1.12e-02 GO:0034660 ncRNA metabolic process
2.35 1.40e-02 GO:0000280 nuclear division
2.35 1.40e-02 GO:0007067 mitosis
1.50 1.51e-02 GO:0031325 positive regulation of cellular metabolic process
3.77 1.59e-02 GO:0006302 double-strand break repair
2.49 1.77e-02 GO:0007346 regulation of mitotic cell cycle
1.29 1.92e-02 GO:0032502 developmental process
2.07 1.99e-02 GO:0016568 chromatin modification
2.30 2.25e-02 GO:0000087 M phase of mitotic cell cycle
2.40 2.42e-02 GO:0071843 cellular component biogenesis at cellular level
2.95 2.76e-02 GO:0071103 DNA conformation change
1.49 2.80e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.13 2.90e-02 GO:0006397 mRNA processing
2.76 3.06e-02 GO:0042254 ribosome biogenesis
2.26 3.26e-02 GO:0048285 organelle fission
6.43 3.41e-02 GO:0032392 DNA geometric change
3.55 3.50e-02 GO:0010212 response to ionizing radiation
1.42 3.73e-02 GO:0006464 protein modification process
1.62 3.84e-02 GO:0009790 embryo development
3.94 3.85e-02 GO:0000082 G1/S transition of mitotic cell cycle
1.46 4.05e-02 GO:0009893 positive regulation of metabolic process
1.59 4.46e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.59 4.62e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.94 4.84e-02 GO:0007059 chromosome segregation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.58 4.32e-60 GO:0043231 intracellular membrane-bounded organelle
1.58 1.19e-59 GO:0043227 membrane-bounded organelle
1.43 2.63e-57 GO:0044424 intracellular part
1.42 2.62e-56 GO:0005622 intracellular
1.50 8.88e-55 GO:0043229 intracellular organelle
1.50 3.83e-54 GO:0043226 organelle
1.80 4.01e-50 GO:0005634 nucleus
2.18 2.50e-28 GO:0044428 nuclear part
1.63 5.96e-24 GO:0044446 intracellular organelle part
1.62 9.57e-24 GO:0044422 organelle part
2.07 8.80e-23 GO:0031974 membrane-enclosed lumen
2.08 1.87e-22 GO:0070013 intracellular organelle lumen
2.07 2.38e-22 GO:0043233 organelle lumen
2.15 1.27e-21 GO:0031981 nuclear lumen
1.35 6.82e-21 GO:0005737 cytoplasm
2.33 6.11e-19 GO:0005654 nucleoplasm
1.13 1.72e-13 GO:0005623 cell
1.13 1.72e-13 GO:0044464 cell part
1.51 7.72e-12 GO:0032991 macromolecular complex
2.22 2.34e-10 GO:0044451 nucleoplasm part
1.33 1.17e-09 GO:0044444 cytoplasmic part
1.50 1.82e-07 GO:0043228 non-membrane-bounded organelle
1.50 1.82e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.43 2.04e-06 GO:0043234 protein complex
2.16 3.20e-06 GO:0030529 ribonucleoprotein complex
2.10 2.52e-05 GO:0005694 chromosome
1.54 6.69e-05 GO:0005739 mitochondrion
2.15 1.25e-04 GO:0005730 nucleolus
2.27 1.59e-04 GO:0005667 transcription factor complex
1.51 4.35e-04 GO:0005829 cytosol
1.96 1.52e-03 GO:0044427 chromosomal part
2.62 1.13e-02 GO:0000775 chromosome, centromeric region
2.55 1.79e-02 GO:0016604 nuclear body
3.02 4.06e-02 GO:0071013 catalytic step 2 spliceosome
2.28 4.86e-02 GO:0005840 ribosome

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.91 4.77e-27 GO:0003676 nucleic acid binding
1.28 3.74e-23 GO:0005488 binding
1.87 8.01e-16 GO:0003677 DNA binding
1.71 2.39e-13 GO:0000166 nucleotide binding
1.71 2.37e-10 GO:0035639 purine ribonucleoside triphosphate binding
1.69 5.43e-10 GO:0017076 purine nucleotide binding
1.67 1.38e-09 GO:0032555 purine ribonucleotide binding
1.67 1.45e-09 GO:0032553 ribonucleotide binding
2.11 7.07e-09 GO:0003723 RNA binding
1.73 1.24e-08 GO:0005524 ATP binding
1.71 1.81e-08 GO:0030554 adenyl nucleotide binding
1.70 4.62e-08 GO:0032559 adenyl ribonucleotide binding
1.26 8.68e-06 GO:0005515 protein binding
1.76 2.30e-05 GO:0030528 transcription regulator activity
2.75 3.93e-05 GO:0043566 structure-specific DNA binding
1.82 4.14e-05 GO:0001071 nucleic acid binding transcription factor activity
1.82 4.14e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.24 2.85e-04 GO:0003824 catalytic activity
1.46 6.95e-04 GO:0016740 transferase activity
4.50 7.56e-04 GO:0003697 single-stranded DNA binding
2.13 2.07e-03 GO:0008134 transcription factor binding
1.75 2.14e-03 GO:0043565 sequence-specific DNA binding
6.03 4.19e-03 GO:0035064 methylated histone residue binding
1.55 1.72e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.75 1.86e-02 GO:0003735 structural constituent of ribosome
1.66 3.27e-02 GO:0017111 nucleoside-triphosphatase activity
2.45 3.30e-02 GO:0000287 magnesium ion binding
1.63 4.14e-02 GO:0016462 pyrophosphatase activity
3.09 4.41e-02 GO:0008026 ATP-dependent helicase activity
3.09 4.41e-02 GO:0070035 purine NTP-dependent helicase activity
1.63 4.75e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.62 4.97e-02 GO:0016817 hydrolase activity, acting on acid anhydrides