• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: EGR1..3.p2

Z-value: 2.355

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_151235861	61.133	NM_001081557 NM_001195565	Camta1	calmodulin binding transcription activator 1
chr11_-_5965555	41.392		Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chr10_-_108447894	40.889		Syt1	synaptotagmin I
chr10_-_108447996	40.326		Syt1	synaptotagmin I
chr10_-_108448003	38.921		Syt1	synaptotagmin I
chrX_+_5624820	37.099		Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr12_+_109572514	35.377	NM_010010	Cyp46a1	cytochrome P450, family 46, subfamily a, polypeptide 1
chrX_-_70905062	34.767	NM_012040	Pnck	pregnancy upregulated non-ubiquitously expressed CaM kinase
chr10_-_108447674	32.662	NM_009306	Syt1	synaptotagmin I
chr11_+_119804400	32.337	NM_001037754 NM_001037755 NM_130862	Baiap2	brain-specific angiogenesis inhibitor 1-associated protein 2
chr9_-_53822931	31.956		Elmod1	ELMO domain containing 1
chr11_-_5965544	31.512		Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chr3_+_28162135	31.461	NM_001163007 NM_001163008 NM_001163009 NM_026910	Tnik	TRAF2 and NCK interacting kinase
chr9_-_53823107	31.312	NM_177769	Elmod1	ELMO domain containing 1
chr18_+_35020867	30.714		Egr1	early growth response 1
chr8_-_126957835	30.473	NM_171824	Pgbd5	piggyBac transposable element derived 5
chrX_-_70905384	29.935		Pnck	pregnancy upregulated non-ubiquitously expressed CaM kinase
chr17_+_25945986	29.680	NM_001164225	Fbxl16	F-box and leucine-rich repeat protein 16
chr15_-_75397243	28.051	NM_001135688	Ly6h	lymphocyte antigen 6 complex, locus H
chrX_-_20498021	27.913	NM_001110780 NM_013680	Syn1	synapsin I
chr10_-_126700387	26.806	NM_001039000 NM_008447	Kif5a	kinesin family member 5A
chr7_+_64846528	26.629	NM_008071	Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr4_+_126846429	26.273	NM_198618	Dlgap3	discs, large (Drosophila) homolog-associated protein 3
chr5_+_37633353	25.827		Crmp1	collapsin response mediator protein 1
chr4_-_91038638	25.573		Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr9_-_37360141	25.528	NM_022029	Nrgn	neurogranin
chr11_+_68901989	25.231		Vamp2	vesicle-associated membrane protein 2
chr10_-_115910911	25.145		Kcnmb4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr5_+_37633317	25.116	NM_001136058	Crmp1	collapsin response mediator protein 1
chr6_-_126594802	25.015		Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1
chrX_+_132373572	24.756	NM_001163015 NM_001163016 NM_001163017	Gprasp2	G protein-coupled receptor associated sorting protein 2
chr7_+_4642529	24.576	NM_001003920 NM_001168572	Brsk1	BR serine/threonine kinase 1
chr10_-_115910578	24.510	NM_021452	Kcnmb4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr7_+_64846558	23.665		Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr3_-_57651409	23.371		Pfn2	profilin 2
chr4_-_91038729	23.037	NM_010486 NM_207686	Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chrX_-_61530170	22.819	NM_178740	Slitrk4	SLIT and NTRK-like family, member 4
chr11_-_5965743	22.815	NM_001174053 NM_001174054 NM_007595	Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chr18_+_35020859	22.108	NM_007913	Egr1	early growth response 1
chr1_+_66515003	22.105	NM_175510	Unc80	unc-80 homolog (C. elegans)
chr11_+_68902025	22.054	NM_009497	Vamp2	vesicle-associated membrane protein 2
chr4_+_137806293	21.872	NM_001099631	Sh2d5	SH2 domain containing 5
chr11_-_65601657	21.722		Map2k4	mitogen-activated protein kinase kinase 4
chr13_+_118391270	20.752		Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr4_-_110024513	20.734	NM_001163397	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_+_27792487	20.538		Pacsin1	protein kinase C and casein kinase substrate in neurons 1
chr15_+_89330287	20.091	NM_021423	Shank3	SH3/ankyrin domain gene 3
chr5_-_139605617	19.487	NM_008923	Prkar1b	protein kinase, cAMP dependent regulatory, type I beta
chr16_-_20621287	19.445	NM_028420	Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2
chr17_+_27792587	19.440	NM_011861	Pacsin1	protein kinase C and casein kinase substrate in neurons 1
chr2_-_118529608	19.351	NM_001081971	Gm1337	predicted gene 1337
chr13_+_48356795	19.297	NM_031166	Id4	inhibitor of DNA binding 4
chr10_-_79602040	18.982		Dos	downstream of Stk11
chr13_+_48356487	18.879		Id4	inhibitor of DNA binding 4
chrX_-_61530035	18.808		Slitrk4	SLIT and NTRK-like family, member 4
chr17_-_25570566	18.677		Cacna1h	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr9_-_86775154	18.520	NM_013669	Snap91	synaptosomal-associated protein 91
chrX_+_7215705	18.470	NM_009305	Syp	synaptophysin
chr3_+_136333670	18.443		Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform
chrX_+_133527693	18.431	NM_001035509 NM_001035510 NM_025893	Zcchc18	zinc finger, CCHC domain containing 18
chr3_+_105255247	18.086	NM_001039347	Kcnd3	potassium voltage-gated channel, Shal-related family, member 3
chr1_+_174271397	17.536		Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10
chr18_+_35021288	17.477		Egr1	early growth response 1
chr17_+_27822162	17.371	NM_178365	Pacsin1	protein kinase C and casein kinase substrate in neurons 1
chr13_-_69877709	17.284		Ube2ql1	ubiquitin-conjugating enzyme E2Q family-like 1
chrX_-_159081510	17.242	NM_178256	Reps2	RALBP1 associated Eps domain containing protein 2
chr15_+_54402914	17.215	NM_178920	Mal2	mal, T-cell differentiation protein 2
chr16_-_18629938	17.208	NM_213614	Sept5	septin 5
chrX_+_5624624	17.156	NM_021431	Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr3_+_133903056	17.102	NM_001004367	Cxxc4	CXXC finger 4
chr4_-_128798481	17.079	NM_010471	Hpca	hippocalcin
chr6_+_117961386	17.010		Rasgef1a	RasGEF domain family, member 1A
chr7_-_52622373	16.962	NM_029741	Ppfia3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr9_-_86775282	16.776		Snap91	synaptosomal-associated protein 91
chr13_-_69138418	16.678	NM_153534	Adcy2	adenylate cyclase 2
chr2_+_177876858	16.384		Phactr3	phosphatase and actin regulator 3
chr7_-_52625929	16.362	NM_011698	Lin7b	lin-7 homolog B (C. elegans)
chr13_-_69138164	16.220		Adcy2	adenylate cyclase 2
chr6_+_22825464	16.158	NM_001081306	Ptprz1	protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr16_+_94592373	16.152		Ttc3	tetratricopeptide repeat domain 3
chr9_+_20836481	16.073	NM_008319	Icam5	intercellular adhesion molecule 5, telencephalin
chr5_+_37637027	16.067	NM_007765	Crmp1	collapsin response mediator protein 1
chr10_+_40603330	16.036	NM_031877	Wasf1	WASP family 1
chr17_+_46390828	15.992	NM_001111142	Gm88	predicted gene 88
chr1_-_37776633	15.940	NM_028096	2010300C02Rik	RIKEN cDNA 2010300C02 gene
chr9_+_107838164	15.916	NM_145621	Camkv	CaM kinase-like vesicle-associated
chr2_+_164312023	15.857		Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr13_-_69138229	15.789		Adcy2	adenylate cyclase 2
chr12_-_113146259	15.750	NM_011625	Ppp1r13b	protein phosphatase 1, regulatory (inhibitor) subunit 13B
chr3_+_136333251	15.691		Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform
chr16_+_35155621	15.543	NM_001012765	Adcy5	adenylate cyclase 5
chr6_-_126595818	15.503	NM_010595	Kcna1	potassium voltage-gated channel, shaker-related subfamily, member 1
chr18_-_25912453	15.391	NM_001146292 NM_001146293 NM_001146294 NM_001146295 NM_001174074 NM_133195	Celf4	CUGBP, Elav-like family member 4
chr9_+_20836560	15.126		Icam5	intercellular adhesion molecule 5, telencephalin
chr10_-_126700105	15.030		Kif5a	kinesin family member 5A
chr5_+_137994744	15.001	NM_031404	Actl6b	actin-like 6B
chr15_-_74502981	14.856	NM_018790	Arc	activity regulated cytoskeletal-associated protein
chr1_-_191167582	14.760	NM_010607	Kcnk2	potassium channel, subfamily K, member 2
chr15_-_75397601	14.706	NM_011837	Ly6h	lymphocyte antigen 6 complex, locus H
chrX_+_45976916	14.463		Slc25a14	solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_-_175297778	14.415	NM_053199	Cadm3	cell adhesion molecule 3
chr10_-_76424532	14.378		Pcbp3	poly(rC) binding protein 3
chr4_+_129662284	14.359	NM_173071	Bai2	brain-specific angiogenesis inhibitor 2
chr1_-_175297624	14.129		Cadm3	cell adhesion molecule 3
chr9_-_41932195	14.127		Sorl1	sortilin-related receptor, LDLR class A repeats-containing
chr5_-_53604536	14.126		Sel1l3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr4_+_138011061	14.126	NM_025451	Camk2n1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr10_-_76424664	14.073	NM_021568	Pcbp3	poly(rC) binding protein 3
chr11_-_69182891	14.059	NM_146019	Chd3	chromodomain helicase DNA binding protein 3
chr7_-_31319977	13.958	NM_178252	Arhgap33	Rho GTPase activating protein 33
chr7_+_4071171	13.903		Ttyh1	tweety homolog 1 (Drosophila)
chr8_+_86939262	13.748	NM_007578	Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr14_-_76956445	13.710	NM_001160326	Serp2	stress-associated endoplasmic reticulum protein family member 2
chrX_-_56387565	13.666	NM_010200	Fgf13	fibroblast growth factor 13
chr15_+_98465328	13.612		Cacnb3	calcium channel, voltage-dependent, beta 3 subunit
chrX_+_45976650	13.548	NM_011398	Slc25a14	solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_-_26460133	13.458		Tmem91	transmembrane protein 91
chr4_+_129662110	13.295		Bai2	brain-specific angiogenesis inhibitor 2
chr7_+_28438881	13.229	NM_028417	Ttc9b	tetratricopeptide repeat domain 9B
chr12_+_45429857	13.157	NM_001146031 NM_176930	Nrcam	neuron-glia-CAM-related cell adhesion molecule
chr9_-_44688946	13.130		Mll1	myeloid/lymphoid or mixed-lineage leukemia 1
chr8_-_74195650	13.074	NM_001029873	Unc13a	unc-13 homolog A (C. elegans)
chr1_+_174271338	12.993	NM_001039484	Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10
chr19_+_3851772	12.886	NM_001025566 NM_013490	Chka	choline kinase alpha
chr13_-_54850954	12.810	NM_012014	Gprin1	G protein-regulated inducer of neurite outgrowth 1
chr2_+_119568028	12.675	NM_146125	Itpka	inositol 1,4,5-trisphosphate 3-kinase A
chr9_+_58430210	12.675		Nptn	neuroplastin
chr3_+_34549057	12.668		Sox2	SRY-box containing gene 2
chr5_+_88994386	12.627		Rufy3	RUN and FYVE domain containing 3
chr12_+_117724182	12.537	NM_011215	Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr12_-_5382487	12.428	NM_001164493	Klhl29	kelch-like 29 (Drosophila)
chr6_+_110595586	12.255	NM_177328	Grm7	glutamate receptor, metabotropic 7
chr2_-_168567602	12.244		Atp9a	ATPase, class II, type 9A
chr6_+_49772688	12.148	NM_023456	Npy	neuropeptide Y
chr19_+_3851856	12.133		Chka	choline kinase alpha
chr2_-_167014273	12.120	NM_008420	Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1
chr2_-_113669159	12.015		Scg5	secretogranin V
chr2_-_113669229	12.008		Scg5	secretogranin V
chr15_-_98593432	11.833		Arf3	ADP-ribosylation factor 3
chr2_+_164311755	11.827	NM_026797	Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr5_+_118477803	11.806	NM_021344	Tesc	tescalcin
chr17_-_64681166	11.782	NM_001025309 NM_144859	Pja2	praja 2, RING-H2 motif containing
chr7_+_19868009	11.736	NM_013648	Rtn2	reticulon 2 (Z-band associated protein)
chr4_-_139802683	11.600	NM_198610	Igsf21	immunoglobin superfamily, member 21
chr7_-_26460180	11.458	NM_177102	Tmem91	transmembrane protein 91
chr12_+_111685371	11.438	NM_001135001	Ppp2r5c	protein phosphatase 2, regulatory subunit B (B56), gamma isoform
chr2_-_113669243	11.423	NM_009162	Scg5	secretogranin V
chr7_-_54387695	11.363		Ptpn5	protein tyrosine phosphatase, non-receptor type 5
chr7_-_52622289	11.348		Ppfia3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr2_+_164793698	11.325		Slc12a5	solute carrier family 12, member 5
chr17_+_37187550	11.281		Gabbr1	gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_77306825	11.276	NM_001004144	Git1	G protein-coupled receptor kinase-interactor 1
chr3_+_136333083	11.269		Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform
chr15_+_76490995	11.239	NM_010630	Kifc2	kinesin family member C2
chr2_-_52532100	11.223	NM_001037099	Cacnb4	calcium channel, voltage-dependent, beta 4 subunit
chr13_+_104899814	11.211		Sgtb	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr11_+_105451296	11.124	NM_181071	Tanc2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr7_+_107376116	11.055	NM_027629	Pgm2l1	phosphoglucomutase 2-like 1
chr8_+_121971001	11.036		Necab2	N-terminal EF-hand calcium binding protein 2
chr1_-_191167231	11.007	NM_001159850	Kcnk2	potassium channel, subfamily K, member 2
chr7_-_31836457	10.991	NM_022007	Fxyd7	FXYD domain-containing ion transport regulator 7
chr1_-_136131981	10.931	NM_001008533 NM_001039510	Adora1	adenosine A1 receptor
chr4_-_133054355	10.726	NM_001081156	Trnp1	TMF1-regulated nuclear protein 1
chr15_+_74346835	10.712		Bai1	brain-specific angiogenesis inhibitor 1
chr7_-_54387915	10.700	NM_001163565	Ptpn5	protein tyrosine phosphatase, non-receptor type 5
chrX_+_7455387	10.674	NM_138606	Pim2	proviral integration site 2
chr18_+_65047408	10.658	NM_001114386	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like
chr2_+_143371807	10.655	NM_008792	Pcsk2	proprotein convertase subtilisin/kexin type 2
chr1_+_75476106	10.494	NM_177056	Tmem198	transmembrane protein 198
chr3_-_152331083	10.494	NM_001081277	Ak5	adenylate kinase 5
chr2_+_70400179	10.462	NM_008077	Gad1	glutamic acid decarboxylase 1
chr15_+_74346624	10.429	NM_174991	Bai1	brain-specific angiogenesis inhibitor 1
chr9_-_41932371	10.390	NM_011436	Sorl1	sortilin-related receptor, LDLR class A repeats-containing
chr4_+_151552208	10.341	NM_133348	AU014716 Acot7	expressed sequence AU014716 acyl-CoA thioesterase 7
chr5_-_122952179	10.313		Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr7_-_28181562	10.272		Spnb4	spectrin beta 4
chr7_+_120350963	10.209	NM_007489	Arntl	aryl hydrocarbon receptor nuclear translocator-like
chr11_-_102417457	10.194	NM_001159492	Gpatch8	G patch domain containing 8
chrX_+_33735898	10.069	NM_028325	Zcchc12	zinc finger, CCHC domain containing 12
chr3_+_136333733	10.017	NM_008913	Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform
chr8_+_91220965	10.016		Cyld	cylindromatosis (turban tumor syndrome)
chr10_+_98377759	9.987	NM_026482	Atp2b1	ATPase, Ca++ transporting, plasma membrane 1
chr5_-_145522423	9.952	NM_177735	Tmem130	transmembrane protein 130
chr19_+_60832080	9.911		Nanos1	nanos homolog 1 (Drosophila)
chr10_+_13685882	9.909		Hivep2	human immunodeficiency virus type I enhancer binding protein 2
chr11_+_69154265	9.890		A030009H04Rik	RIKEN cDNA A030009H04 gene
chr5_-_53604673	9.853	NM_172710	Sel1l3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr9_+_14080805	9.848		Sesn3	sestrin 3
chr3_+_136333793	9.843		Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform
chr15_+_98465193	9.776	NM_007581	Cacnb3	calcium channel, voltage-dependent, beta 3 subunit
chr19_-_43598949	9.761	NM_010324	Got1	glutamate oxaloacetate transaminase 1, soluble
chr15_+_12047769	9.760		Zfr	zinc finger RNA binding protein
chr5_-_122952228	9.728	NM_001110140 NM_009722	Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr3_-_8667013	9.716	NM_010423	Hey1	hairy/enhancer-of-split related with YRPW motif 1
chr11_-_35612058	9.673		Fbll1	fibrillarin-like 1
chr5_-_135554038	9.656	NM_177574	Vps37d	vacuolar protein sorting 37D (yeast)
chr3_-_119486305	9.655	NM_019550	Ptbp2	polypyrimidine tract binding protein 2
chr7_-_25857275	9.642	NM_008168	Grik5	glutamate receptor, ionotropic, kainate 5 (gamma 2)
chr2_+_164312087	9.582		Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_+_25733392	9.574		Kcnt1	potassium channel, subfamily T, member 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.87	4.43e-21	GO:0007399	nervous system development
1.42	9.28e-16	GO:0051179	localization
1.38	3.81e-15	GO:0031323	regulation of cellular metabolic process
1.35	8.23e-15	GO:0019222	regulation of metabolic process
1.60	1.69e-14	GO:0006464	protein modification process
1.45	1.84e-14	GO:0006810	transport
1.44	5.31e-14	GO:0051234	establishment of localization
1.86	1.22e-13	GO:0022008	neurogenesis
1.37	1.32e-13	GO:0080090	regulation of primary metabolic process
1.30	1.84e-13	GO:0044260	cellular macromolecule metabolic process
1.56	3.28e-13	GO:0043412	macromolecule modification
1.88	4.78e-13	GO:0048699	generation of neurons
1.24	6.76e-13	GO:0044237	cellular metabolic process
2.37	7.73e-13	GO:0019226	transmission of nerve impulse
2.37	7.73e-13	GO:0035637	multicellular organismal signaling
1.42	1.06e-12	GO:0051171	regulation of nitrogen compound metabolic process
1.42	1.13e-12	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48	2.16e-12	GO:0071842	cellular component organization at cellular level
2.32	1.39e-11	GO:0031175	neuron projection development
1.38	7.29e-11	GO:0016043	cellular component organization
1.35	9.81e-11	GO:0032502	developmental process
1.43	1.04e-10	GO:0071841	cellular component organization or biogenesis at cellular level
1.96	2.03e-10	GO:0030182	neuron differentiation
1.33	3.58e-10	GO:0060255	regulation of macromolecule metabolic process
2.36	1.26e-09	GO:0007268	synaptic transmission
1.37	1.50e-09	GO:0010468	regulation of gene expression
1.35	1.53e-09	GO:0071840	cellular component organization or biogenesis
1.35	1.56e-09	GO:0007275	multicellular organismal development
1.24	1.62e-09	GO:0043170	macromolecule metabolic process
1.21	1.82e-09	GO:0044238	primary metabolic process
1.11	4.05e-09	GO:0009987	cellular process
2.35	4.94e-09	GO:0048812	neuron projection morphogenesis
1.95	5.38e-09	GO:0030030	cell projection organization
1.36	6.95e-09	GO:0048856	anatomical structure development
1.43	7.55e-09	GO:0030154	cell differentiation
1.63	9.93e-09	GO:0006796	phosphate metabolic process
2.01	1.03e-08	GO:0048666	neuron development
2.44	1.06e-08	GO:0007409	axonogenesis
1.62	1.21e-08	GO:0006793	phosphorus metabolic process
2.36	1.26e-08	GO:0048667	cell morphogenesis involved in neuron differentiation
1.38	1.29e-08	GO:0051252	regulation of RNA metabolic process
1.35	1.72e-08	GO:0031326	regulation of cellular biosynthetic process
1.39	1.80e-08	GO:0044267	cellular protein metabolic process
1.41	3.25e-08	GO:0048869	cellular developmental process
1.34	3.34e-08	GO:0009889	regulation of biosynthetic process
1.60	3.55e-08	GO:0035556	intracellular signal transduction
1.37	3.65e-08	GO:0048731	system development
1.49	4.87e-08	GO:0065009	regulation of molecular function
1.66	5.34e-08	GO:0048468	cell development
1.17	5.35e-08	GO:0008152	metabolic process
1.49	7.18e-08	GO:0023051	regulation of signaling
1.76	8.14e-08	GO:0007154	cell communication
1.35	8.29e-08	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.37	1.02e-07	GO:0006355	regulation of transcription, DNA-dependent
1.59	1.05e-07	GO:0051641	cellular localization
4.35	2.85e-07	GO:0048168	regulation of neuronal synaptic plasticity
1.29	4.63e-07	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.08	6.18e-07	GO:0048858	cell projection morphogenesis
2.49	6.59e-07	GO:0042391	regulation of membrane potential
2.07	7.32e-07	GO:0000904	cell morphogenesis involved in differentiation
2.04	7.75e-07	GO:0016568	chromatin modification
1.92	8.22e-07	GO:0007267	cell-cell signaling
1.41	9.34e-07	GO:0006351	transcription, DNA-dependent
1.46	9.59e-07	GO:0006996	organelle organization
1.33	1.08e-06	GO:0010556	regulation of macromolecule biosynthetic process
1.41	1.14e-06	GO:0032774	RNA biosynthetic process
1.15	1.49e-06	GO:0050794	regulation of cellular process
2.04	1.67e-06	GO:0032990	cell part morphogenesis
2.61	1.82e-06	GO:0007626	locomotory behavior
1.93	2.38e-06	GO:0006325	chromatin organization
1.71	3.75e-06	GO:0016192	vesicle-mediated transport
2.01	4.08e-06	GO:0070647	protein modification by small protein conjugation or removal
1.49	4.80e-06	GO:0033036	macromolecule localization
1.77	7.41e-06	GO:0030001	metal ion transport
3.17	8.43e-06	GO:0048167	regulation of synaptic plasticity
2.10	8.60e-06	GO:0032446	protein modification by small protein conjugation
2.14	9.87e-06	GO:0016567	protein ubiquitination
1.33	1.01e-05	GO:0016070	RNA metabolic process
1.86	1.15e-05	GO:0060284	regulation of cell development
1.58	1.32e-05	GO:0016310	phosphorylation
1.52	1.37e-05	GO:0008104	protein localization
1.88	1.40e-05	GO:0007610	behavior
1.61	2.04e-05	GO:0051049	regulation of transport
1.92	2.34e-05	GO:0007420	brain development
2.24	2.54e-05	GO:0050804	regulation of synaptic transmission
1.80	2.58e-05	GO:0000902	cell morphogenesis
1.80	2.58e-05	GO:0007417	central nervous system development
1.25	2.79e-05	GO:0034641	cellular nitrogen compound metabolic process
1.58	2.80e-05	GO:0006811	ion transport
1.14	3.06e-05	GO:0050789	regulation of biological process
1.62	3.12e-05	GO:0006468	protein phosphorylation
1.56	3.34e-05	GO:0051649	establishment of localization in cell
1.56	4.36e-05	GO:0051128	regulation of cellular component organization
1.91	4.47e-05	GO:0050767	regulation of neurogenesis
1.30	4.89e-05	GO:0048522	positive regulation of cellular process
2.16	5.79e-05	GO:0051969	regulation of transmission of nerve impulse
1.32	5.81e-05	GO:0048523	negative regulation of cellular process
1.75	5.81e-05	GO:0032989	cellular component morphogenesis
1.31	6.40e-05	GO:0048519	negative regulation of biological process
1.66	7.01e-05	GO:0006812	cation transport
1.28	7.22e-05	GO:0048518	positive regulation of biological process
2.80	8.82e-05	GO:0034765	regulation of ion transmembrane transport
1.13	9.39e-05	GO:0065007	biological regulation
1.89	1.13e-04	GO:0009894	regulation of catabolic process
1.23	1.29e-04	GO:0006807	nitrogen compound metabolic process
2.06	1.98e-04	GO:0031644	regulation of neurological system process
1.92	3.18e-04	GO:0018193	peptidyl-amino acid modification
1.38	3.34e-04	GO:0051239	regulation of multicellular organismal process
1.94	3.42e-04	GO:0045664	regulation of neuron differentiation
1.53	4.02e-04	GO:0045184	establishment of protein localization
2.13	4.21e-04	GO:0043269	regulation of ion transport
4.20	4.21e-04	GO:0007628	adult walking behavior
1.99	4.27e-04	GO:0051056	regulation of small GTPase mediated signal transduction
1.53	5.03e-04	GO:0015031	protein transport
1.26	5.05e-04	GO:0019538	protein metabolic process
1.73	5.87e-04	GO:0016044	cellular membrane organization
2.30	5.97e-04	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.30	5.97e-04	GO:0022604	regulation of cell morphogenesis
1.75	6.10e-04	GO:0044057	regulation of system process
2.03	6.94e-04	GO:0030900	forebrain development
1.72	7.34e-04	GO:0061024	membrane organization
1.66	7.88e-04	GO:0051276	chromosome organization
4.20	1.01e-03	GO:0048169	regulation of long-term neuronal synaptic plasticity
2.37	1.03e-03	GO:0043087	regulation of GTPase activity
2.02	1.05e-03	GO:0046578	regulation of Ras protein signal transduction
1.89	1.19e-03	GO:0006140	regulation of nucleotide metabolic process
2.35	1.28e-03	GO:0033124	regulation of GTP catabolic process
1.76	1.30e-03	GO:0051960	regulation of nervous system development
1.25	1.39e-03	GO:0090304	nucleic acid metabolic process
2.09	1.40e-03	GO:0016570	histone modification
2.29	1.88e-03	GO:0050890	cognition
2.78	1.98e-03	GO:0001505	regulation of neurotransmitter levels
1.87	2.31e-03	GO:0007264	small GTPase mediated signal transduction
2.05	2.32e-03	GO:0016569	covalent chromatin modification
1.61	2.55e-03	GO:0019725	cellular homeostasis
1.39	2.64e-03	GO:0009966	regulation of signal transduction
1.25	2.85e-03	GO:0010467	gene expression
1.74	3.02e-03	GO:0006163	purine nucleotide metabolic process
1.95	3.60e-03	GO:0006897	endocytosis
1.95	3.60e-03	GO:0010324	membrane invagination
1.52	3.64e-03	GO:0008219	cell death
1.52	3.76e-03	GO:0016265	death
1.83	3.96e-03	GO:0009141	nucleoside triphosphate metabolic process
2.79	5.07e-03	GO:0008344	adult locomotory behavior
3.33	5.56e-03	GO:0007269	neurotransmitter secretion
3.33	5.56e-03	GO:0007270	nerve-nerve synaptic transmission
3.46	5.70e-03	GO:0021954	central nervous system neuron development
1.65	5.78e-03	GO:0006873	cellular ion homeostasis
1.83	6.46e-03	GO:0009205	purine ribonucleoside triphosphate metabolic process
2.44	6.71e-03	GO:0021953	central nervous system neuron differentiation
1.83	7.35e-03	GO:0031329	regulation of cellular catabolic process
2.20	7.83e-03	GO:0010720	positive regulation of cell development
2.79	8.14e-03	GO:0017157	regulation of exocytosis
1.37	8.24e-03	GO:0050790	regulation of catalytic activity
1.40	8.30e-03	GO:0010646	regulation of cell communication
2.94	8.31e-03	GO:0032412	regulation of ion transmembrane transporter activity
3.70	8.33e-03	GO:0014075	response to amine stimulus
1.82	8.35e-03	GO:0009199	ribonucleoside triphosphate metabolic process
2.50	8.38e-03	GO:0006836	neurotransmitter transport
1.30	9.08e-03	GO:0065008	regulation of biological quality
4.06	1.04e-02	GO:0035249	synaptic transmission, glutamatergic
1.90	1.10e-02	GO:0009154	purine ribonucleotide catabolic process
1.77	1.21e-02	GO:0033043	regulation of organelle organization
1.90	1.23e-02	GO:0009207	purine ribonucleoside triphosphate catabolic process
2.13	1.27e-02	GO:0030811	regulation of nucleotide catabolic process
2.13	1.27e-02	GO:0033121	regulation of purine nucleotide catabolic process
1.64	1.27e-02	GO:0040008	regulation of growth
2.37	1.32e-02	GO:0030534	adult behavior
1.85	1.33e-02	GO:0006195	purine nucleotide catabolic process
1.79	1.38e-02	GO:0009144	purine nucleoside triphosphate metabolic process
1.89	1.42e-02	GO:0009203	ribonucleoside triphosphate catabolic process
2.71	1.44e-02	GO:0032409	regulation of transporter activity
1.87	1.66e-02	GO:0009143	nucleoside triphosphate catabolic process
1.52	1.66e-02	GO:0046907	intracellular transport
1.61	1.69e-02	GO:0055082	cellular chemical homeostasis
1.71	1.81e-02	GO:0051046	regulation of secretion
2.90	1.83e-02	GO:0050808	synapse organization
1.88	1.86e-02	GO:0009146	purine nucleoside triphosphate catabolic process
1.86	1.90e-02	GO:0009261	ribonucleotide catabolic process
1.58	2.03e-02	GO:0006753	nucleoside phosphate metabolic process
1.58	2.03e-02	GO:0009117	nucleotide metabolic process
2.01	2.05e-02	GO:0010975	regulation of neuron projection development
2.80	2.10e-02	GO:0022898	regulation of transmembrane transporter activity
1.58	2.11e-02	GO:0050801	ion homeostasis
1.38	2.16e-02	GO:0051246	regulation of protein metabolic process
1.63	2.36e-02	GO:0072521	purine-containing compound metabolic process
1.74	2.47e-02	GO:0009150	purine ribonucleotide metabolic process
2.75	2.80e-02	GO:0070588	calcium ion transmembrane transport
1.80	2.88e-02	GO:0072523	purine-containing compound catabolic process
2.28	3.06e-02	GO:0032318	regulation of Ras GTPase activity
1.76	3.21e-02	GO:0043632	modification-dependent macromolecule catabolic process
2.43	3.41e-02	GO:0001508	regulation of action potential
2.09	3.57e-02	GO:0010959	regulation of metal ion transport
1.39	3.75e-02	GO:0032268	regulation of cellular protein metabolic process
2.56	4.17e-02	GO:0040014	regulation of multicellular organism growth
3.17	4.30e-02	GO:0010243	response to organic nitrogen
1.89	4.36e-02	GO:0031344	regulation of cell projection organization
1.48	4.46e-02	GO:0012501	programmed cell death
1.33	4.47e-02	GO:0010604	positive regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.26	7.96e-45	GO:0005622	intracellular
1.25	6.48e-40	GO:0044424	intracellular part
2.62	2.36e-33	GO:0043005	neuron projection
2.71	2.75e-31	GO:0045202	synapse
1.28	1.47e-28	GO:0005737	cytoplasm
1.13	4.04e-28	GO:0005623	cell
1.13	4.04e-28	GO:0044464	cell part
1.24	8.02e-27	GO:0043229	intracellular organelle
3.11	1.16e-26	GO:0030425	dendrite
1.24	1.38e-26	GO:0043226	organelle
2.83	3.00e-24	GO:0044456	synapse part
1.24	9.39e-22	GO:0043231	intracellular membrane-bounded organelle
1.24	9.53e-22	GO:0043227	membrane-bounded organelle
1.36	1.34e-21	GO:0005634	nucleus
1.87	1.26e-20	GO:0042995	cell projection
2.38	8.56e-18	GO:0044463	cell projection part
2.75	4.19e-17	GO:0030424	axon
2.41	6.10e-15	GO:0044297	cell body
2.42	1.57e-14	GO:0043025	neuronal cell body
1.41	9.97e-14	GO:0043234	protein complex
1.36	8.97e-13	GO:0032991	macromolecular complex
2.83	5.60e-11	GO:0045211	postsynaptic membrane
3.79	1.12e-10	GO:0044309	neuron spine
3.02	1.14e-10	GO:0033267	axon part
1.28	3.56e-10	GO:0044446	intracellular organelle part
1.29	7.46e-10	GO:0071944	cell periphery
3.68	1.63e-09	GO:0043197	dendritic spine
1.27	1.69e-09	GO:0044422	organelle part
3.43	4.29e-09	GO:0014069	postsynaptic density
2.81	6.75e-09	GO:0019717	synaptosome
1.28	7.47e-09	GO:0005886	plasma membrane
3.12	1.70e-08	GO:0008021	synaptic vesicle
2.67	3.08e-08	GO:0030136	clathrin-coated vesicle
1.46	8.63e-08	GO:0005856	cytoskeleton
1.59	1.14e-07	GO:0005626	insoluble fraction
2.50	1.26e-07	GO:0030135	coated vesicle
1.51	1.61e-07	GO:0000267	cell fraction
1.59	1.83e-07	GO:0005624	membrane fraction
2.42	3.20e-07	GO:0034702	ion channel complex
2.81	1.54e-06	GO:0034703	cation channel complex
3.00	3.28e-06	GO:0044306	neuron projection terminus
4.06	3.48e-06	GO:0042734	presynaptic membrane
1.65	4.04e-06	GO:0030054	cell junction
1.52	5.40e-06	GO:0044430	cytoskeletal part
4.06	8.30e-06	GO:0043198	dendritic shaft
1.18	9.21e-06	GO:0044444	cytoplasmic part
1.30	1.23e-05	GO:0043228	non-membrane-bounded organelle
1.30	1.23e-05	GO:0043232	intracellular non-membrane-bounded organelle
1.66	1.39e-05	GO:0015630	microtubule cytoskeleton
2.92	3.50e-05	GO:0043679	axon terminus
1.53	6.51e-05	GO:0031982	vesicle
3.31	6.61e-05	GO:0030665	clathrin coated vesicle membrane
1.55	7.59e-05	GO:0031410	cytoplasmic vesicle
2.21	1.17e-04	GO:0044433	cytoplasmic vesicle part
2.23	1.23e-04	GO:0030659	cytoplasmic vesicle membrane
1.32	1.89e-04	GO:0044459	plasma membrane part
2.11	3.25e-04	GO:0012506	vesicle membrane
1.88	3.45e-04	GO:0005874	microtubule
5.42	6.57e-04	GO:0005891	voltage-gated calcium channel complex
3.81	7.82e-04	GO:0008287	protein serine/threonine phosphatase complex
2.79	1.24e-03	GO:0008076	voltage-gated potassium channel complex
2.79	1.24e-03	GO:0034705	potassium channel complex
2.67	2.90e-03	GO:0030662	coated vesicle membrane
1.31	2.91e-03	GO:0005829	cytosol
3.67	3.03e-03	GO:0044304	main axon
1.55	3.13e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.28	3.25e-03	GO:0044428	nuclear part
1.53	3.67e-03	GO:0031988	membrane-bounded vesicle
1.44	3.71e-03	GO:0012505	endomembrane system
4.26	5.20e-03	GO:0034704	calcium channel complex
1.72	7.54e-03	GO:0044431	Golgi apparatus part
2.42	8.26e-03	GO:0030427	site of polarized growth
1.97	1.39e-02	GO:0000139	Golgi membrane
3.13	1.50e-02	GO:0030118	clathrin coat
1.36	2.07e-02	GO:0005794	Golgi apparatus
1.87	3.04e-02	GO:0031252	cell leading edge
4.65	3.95e-02	GO:0030125	clathrin vesicle coat
4.65	3.95e-02	GO:0048786	presynaptic active zone
2.31	4.01e-02	GO:0030426	growth cone
3.36	4.05e-02	GO:0030672	synaptic vesicle membrane
5.17	4.48e-02	GO:0071565	nBAF complex
2.24	4.68e-02	GO:0009898	internal side of plasma membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.24	1.80e-35	GO:0005488	binding
1.41	1.56e-34	GO:0005515	protein binding
1.48	1.19e-13	GO:0000166	nucleotide binding
2.09	2.28e-10	GO:0030695	GTPase regulator activity
1.32	2.46e-10	GO:0046872	metal ion binding
2.07	2.68e-10	GO:0060589	nucleoside-triphosphatase regulator activity
1.47	3.10e-10	GO:0032555	purine ribonucleotide binding
1.47	3.34e-10	GO:0032553	ribonucleotide binding
1.71	3.61e-10	GO:0019899	enzyme binding
1.46	5.22e-10	GO:0017076	purine nucleotide binding
1.31	5.98e-10	GO:0043169	cation binding
1.47	8.53e-10	GO:0035639	purine ribonucleoside triphosphate binding
1.31	1.14e-09	GO:0043167	ion binding
2.16	5.01e-08	GO:0022836	gated channel activity
1.48	1.36e-07	GO:0008270	zinc ion binding
1.80	1.45e-07	GO:0019904	protein domain specific binding
2.73	1.49e-07	GO:0022843	voltage-gated cation channel activity
1.67	7.18e-07	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.76	1.16e-06	GO:0008092	cytoskeletal protein binding
2.35	1.64e-06	GO:0005244	voltage-gated ion channel activity
2.35	1.64e-06	GO:0022832	voltage-gated channel activity
1.59	1.91e-06	GO:0016301	kinase activity
2.10	2.89e-06	GO:0005083	small GTPase regulator activity
1.84	4.01e-06	GO:0004674	protein serine/threonine kinase activity
1.64	4.54e-06	GO:0015075	ion transmembrane transporter activity
1.55	9.08e-06	GO:0030234	enzyme regulator activity
2.17	1.26e-05	GO:0005096	GTPase activator activity
1.85	1.35e-05	GO:0005216	ion channel activity
1.67	1.57e-05	GO:0004672	protein kinase activity
1.40	1.78e-05	GO:0032559	adenyl ribonucleotide binding
1.39	2.76e-05	GO:0030554	adenyl nucleotide binding
1.81	3.78e-05	GO:0022838	substrate-specific channel activity
1.89	4.25e-05	GO:0008134	transcription factor binding
1.36	4.25e-05	GO:0046914	transition metal ion binding
1.54	5.40e-05	GO:0022891	substrate-specific transmembrane transporter activity
1.69	5.57e-05	GO:0008324	cation transmembrane transporter activity
1.48	7.26e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.38	7.70e-05	GO:0005524	ATP binding
1.77	7.86e-05	GO:0015267	channel activity
1.77	8.86e-05	GO:0022803	passive transmembrane transporter activity
1.87	9.43e-05	GO:0008047	enzyme activator activity
4.06	1.95e-04	GO:0035254	glutamate receptor binding
2.01	2.26e-04	GO:0016881	acid-amino acid ligase activity
2.06	3.08e-04	GO:0019787	small conjugating protein ligase activity
1.47	3.47e-04	GO:0022892	substrate-specific transporter activity
4.59	4.26e-04	GO:0005245	voltage-gated calcium channel activity
1.91	4.89e-04	GO:0005261	cation channel activity
1.76	4.94e-04	GO:0019001	guanyl nucleotide binding
1.76	4.94e-04	GO:0032561	guanyl ribonucleotide binding
1.16	5.64e-04	GO:0003824	catalytic activity
1.82	6.38e-04	GO:0019900	kinase binding
1.77	6.38e-04	GO:0005525	GTP binding
2.56	8.36e-04	GO:0030165	PDZ domain binding
2.31	1.02e-03	GO:0005516	calmodulin binding
1.91	1.04e-03	GO:0016791	phosphatase activity
2.04	1.19e-03	GO:0004842	ubiquitin-protein ligase activity
1.45	1.19e-03	GO:0022857	transmembrane transporter activity
2.23	3.59e-03	GO:0051020	GTPase binding
1.72	4.29e-03	GO:0042578	phosphoric ester hydrolase activity
1.82	4.56e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.68	4.72e-03	GO:0032403	protein complex binding
2.29	5.08e-03	GO:0031267	small GTPase binding
1.81	5.18e-03	GO:0019901	protein kinase binding
2.44	5.59e-03	GO:0005249	voltage-gated potassium channel activity
2.33	6.73e-03	GO:0017016	Ras GTPase binding
1.60	1.32e-02	GO:0016874	ligase activity
1.27	1.73e-02	GO:0016740	transferase activity
1.35	2.00e-02	GO:0005215	transporter activity
1.68	2.17e-02	GO:0003779	actin binding
4.06	3.85e-02	GO:0035255	ionotropic glutamate receptor binding
1.36	4.44e-02	GO:0030528	transcription regulator activity
1.43	4.57e-02	GO:0016462	pyrophosphatase activity