• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: EHF.p2

Z-value: 1.915

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_70468019	14.635		Pfn1	profilin 1
chr12_-_81744771	12.262	NM_007951	Erh	enhancer of rudimentary homolog (Drosophila)
chr5_+_122841885	11.907	NM_019824	Arpc3	actin related protein 2/3 complex, subunit 3
chr19_-_5366600	11.666	NM_011793	Banf1	barrier to autointegration factor 1
chr11_-_86497242	11.114	NM_029478	Tmem49	transmembrane protein 49
chr4_-_122563299	10.770		Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)
chr11_+_95896239	10.638		Snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr7_+_28914482	10.496	NM_001164655	9530053A07Rik	RIKEN cDNA 9530053A07 gene
chr19_-_7292086	10.365	NM_007750	Cox8a	cytochrome c oxidase, subunit VIIIa
chr4_-_122563074	9.783	NM_007598	Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)
chr11_+_95896221	9.501	NM_033568	Snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr10_+_127472401	9.477	NM_001113199 NM_013608	Naca	nascent polypeptide-associated complex alpha polypeptide
chr16_+_10412017	9.390	NM_011955	Nubp1	nucleotide binding protein 1
chr16_-_31948214	9.181
chr2_+_5766079	9.175	NM_016918	Nudt5	nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr3_-_27052794	9.124	NM_001177626	Ect2	ect2 oncogene
chr16_+_48994292	9.113	NM_172616	C330027C09Rik	RIKEN cDNA C330027C09 gene
chr8_+_87604829	9.010	NM_001001493	BC056474	cDNA sequence BC056474
chr4_+_131830270	8.987	NM_025579	Taf12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr19_+_6085096	8.831	NM_026410	Cdca5	cell division cycle associated 5
chr1_-_134036041	8.620	NM_008795	Cdk18	cyclin-dependent kinase 18
chr2_-_38499436	8.593		Psmb7	proteasome (prosome, macropain) subunit, beta type 7
chr5_+_145875080	8.522	NM_023142	Arpc1b	actin related protein 2/3 complex, subunit 1B
chr6_+_113328105	8.455	NM_001170485 NM_001170486 NM_026552	Arpc4	actin related protein 2/3 complex, subunit 4
chr2_-_38499375	8.412	NM_011187	Psmb7	proteasome (prosome, macropain) subunit, beta type 7
chr7_+_28856254	8.128	NM_001122603	Fcgbp	Fc fragment of IgG binding protein
chr8_-_125736614	7.955		Chmp1a	chromatin modifying protein 1A
chr19_-_5366324	7.949	NM_001038231	Banf1	barrier to autointegration factor 1
chr10_+_127472624	7.887		Naca	nascent polypeptide-associated complex alpha polypeptide
chr3_-_27052733	7.685	NM_001177625 NM_007900	Ect2	ect2 oncogene
chr10_+_127472725	7.588		Naca	nascent polypeptide-associated complex alpha polypeptide
chrX_-_165758200	7.574	NM_008222	Hccs	holocytochrome c synthetase
chr6_-_29559792	7.389		Tnpo3	transportin 3
chr10_-_80260968	7.369		Plekhj1	pleckstrin homology domain containing, family J member 1
chr11_-_70468061	7.362		Pfn1	profilin 1
chr4_-_135609269	7.353		Rpl11	ribosomal protein L11
chr8_-_86097128	7.348		Tecr	trans-2,3-enoyl-CoA reductase
chr15_-_75839859	7.339	NM_001168253	Fam83h	family with sequence similarity 83, member H
chr10_-_80260534	7.286		Plekhj1	pleckstrin homology domain containing, family J member 1
chr11_-_70468130	7.052	NM_011072	Pfn1	profilin 1
chr4_+_138748812	7.026	NM_009798 NM_001037761	Capzb	capping protein (actin filament) muscle Z-line, beta
chr6_-_87788752	6.978	NM_133934	Isy1	ISY1 splicing factor homolog (S. cerevisiae)
chr19_+_55390514	6.930		Vti1a	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
chr11_+_4795308	6.919	NM_172438	Thoc5	THO complex 5
chr6_-_86743518	6.858	NM_013471	Anxa4	annexin A4
chr4_+_108520389	6.842	NM_029571	Kti12	KTI12 homolog, chromatin associated (S. cerevisiae)
chr19_+_5366979	6.840		Eif1ad	eukaryotic translation initiation factor 1A domain containing
chr12_-_86311718	6.809	NM_178065	1110018G07Rik	RIKEN cDNA 1110018G07 gene
chr2_-_155652217	6.805		Eif6	eukaryotic translation initiation factor 6
chr8_-_125736639	6.797		Chmp1a	chromatin modifying protein 1A
chr9_+_69860449	6.771		Gtf2a2	general transcription factor II A, 2
chr11_+_43247235	6.735		Slu7	SLU7 splicing factor homolog (S. cerevisiae)
chr10_-_22451093	6.730		Tbpl1	TATA box binding protein-like 1
chr3_-_117571853	6.653	NM_001190156 NM_029655	Snx7	sorting nexin 7
chr6_-_87788729	6.535		Isy1	ISY1 splicing factor homolog (S. cerevisiae)
chr8_-_125736641	6.523	NM_145606	Chmp1a	chromatin modifying protein 1A
chr1_-_174012771	6.472	NM_021607	Ncstn	nicastrin
chr5_+_148672171	6.435	NM_025624	Pomp	proteasome maturation protein
chr11_-_104411728	6.397	NM_145436	Cdc27	cell division cycle 27 homolog (S. cerevisiae)
chr5_+_144165482	6.321	NM_025841	Kdelr2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr10_-_60610398	6.285	NM_009163	Sgpl1	sphingosine phosphate lyase 1
chr19_-_7292057	6.248		Cox8a	cytochrome c oxidase, subunit VIIIa
chr11_-_17111582	6.179	NM_025443	Pno1	partner of NOB1 homolog (S. cerevisiae)
chr1_+_89110855	6.134		Eif4e2	eukaryotic translation initiation factor 4E member 2
chr7_-_117129643	6.097		Tmem41b	transmembrane protein 41B
chr7_-_13623543	6.084	NM_001168469	Ube2m	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
chr5_-_100845171	6.059	NM_026969	Sec31a	Sec31 homolog A (S. cerevisiae)
chr5_-_38952934	5.993		Wdr1	WD repeat domain 1
chr8_+_40068850	5.898	NM_030254	Tusc3	tumor suppressor candidate 3
chr10_-_22451211	5.887	NM_011603	Tbpl1	TATA box binding protein-like 1
chr16_-_17111300	5.879	NM_144954	Ppil2	peptidylprolyl isomerase (cyclophilin)-like 2
chrX_+_34337066	5.870		Slc25a5	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr7_-_31758185	5.799		Lsr	lipolysis stimulated lipoprotein receptor
chr3_-_117571789	5.738		Snx7	sorting nexin 7
chr11_-_17111513	5.725		Pno1	partner of NOB1 homolog (S. cerevisiae)
chr17_-_37088436	5.676		Ppp1r11	protein phosphatase 1, regulatory (inhibitor) subunit 11
chr10_-_60610238	5.667		Sgpl1	sphingosine phosphate lyase 1
chr17_-_71199129	5.657	NM_001164076	Tgif1	TGFB-induced factor homeobox 1
chr6_-_86634476	5.594	NM_025665	Snrnp27	small nuclear ribonucleoprotein 27 (U4/U6.U5)
chr11_+_94491055	5.577	NM_133807	Lrrc59	leucine rich repeat containing 59
chrX_-_35917684	5.571		Cul4b	cullin 4B
chr19_-_15980291	5.567		Psat1	phosphoserine aminotransferase 1
chr14_-_56290697	5.553	NM_008683	Nedd8	neural precursor cell expressed, developmentally down-regulated gene 8
chr2_-_155652660	5.551	NM_010579	Eif6	eukaryotic translation initiation factor 6
chr11_-_69476065	5.539		Mpdu1	mannose-P-dolichol utilization defect 1
chr5_-_38952777	5.516	NM_011715	Wdr1	WD repeat domain 1
chr19_-_4928237	5.515	NM_133803	Dpp3	dipeptidylpeptidase 3
chr4_+_155177707	5.480	NM_025570	Mrpl20	mitochondrial ribosomal protein L20
chr2_+_83564607	5.473		Itgav	integrin alpha V
chr9_+_57758783	5.448	NM_001122873 NM_027086	Ubl7	ubiquitin-like 7 (bone marrow stromal cell-derived)
chr11_+_51433236	5.412	NM_026631	Nhp2	NHP2 ribonucleoprotein homolog (yeast)
chr2_+_57090707	5.358	NM_010274	Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial
chr11_-_69485800	5.350		Eif4a1	eukaryotic translation initiation factor 4A1
chr8_+_112302530	5.331	NM_009677	Ap1g1	adaptor protein complex AP-1, gamma 1 subunit
chr10_-_80261226	5.318	NM_023900	Plekhj1	pleckstrin homology domain containing, family J member 1
chr7_-_52317768	5.311		Prrg2	proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr8_+_87604638	5.296		BC056474	cDNA sequence BC056474
chr11_+_96902859	5.251	NM_026154	Mrpl10	mitochondrial ribosomal protein L10
chr5_+_144165615	5.246		Kdelr2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr17_-_27702625	5.232	NM_001002895	AI413582	expressed sequence AI413582
chr19_-_7292009	5.212		Cox8a	cytochrome c oxidase, subunit VIIIa
chr7_-_29965419	5.198		Psmd8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr3_+_95087357	5.161		Fam63a	family with sequence similarity 63, member A
chr7_+_52105323	5.095		Akt1s1	AKT1 substrate 1 (proline-rich)
chr12_+_88784829	5.081	NM_026958	1810035L17Rik	RIKEN cDNA 1810035L17 gene
chr1_+_59741800	5.050	NM_018868	Nop58	NOP58 ribonucleoprotein homolog (yeast)
chr11_-_69485842	5.036	NM_001159375 NM_144958	Eif4a1	eukaryotic translation initiation factor 4A1
chr6_-_35489703	5.033		Mtpn	myotrophin
chr7_+_17323737	4.991	NM_198613	Ap2s1	adaptor-related protein complex 2, sigma 1 subunit
chr1_+_173433762	4.947		Refbp2	RNA and export factor binding protein 2
chr1_+_58852217	4.940	NM_009812	Casp8	caspase 8
chr4_-_45333366	4.919	NM_025513	Exosc3	exosome component 3
chr11_+_81849074	4.908	NM_011333	Ccl2	chemokine (C-C motif) ligand 2
chr12_+_88784853	4.903		1810035L17Rik	RIKEN cDNA 1810035L17 gene
chr14_-_27489331	4.894	NM_178668	Pde12	phosphodiesterase 12
chr14_-_27489119	4.836		Pde12	phosphodiesterase 12
chr6_-_35489875	4.808	NM_008098	Mtpn	myotrophin
chr15_-_81191176	4.785	NM_011399	Slc25a17	solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chr7_-_29965655	4.785	NM_026545	Psmd8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr7_-_29965500	4.785		Psmd8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr19_-_4269096	4.783		Ssh3	slingshot homolog 3 (Drosophila)
chrX_-_98417753	4.729	NM_001110310 NM_001110311 NM_018875	Snx12	sorting nexin 12
chr5_-_137521896	4.726	NM_007457	Ap1s1	adaptor protein complex AP-1, sigma 1
chr4_+_155079379	4.713		Ssu72	Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)
chr2_-_172195998	4.710	NM_011497	Aurka	aurora kinase A
chr2_+_167318144	4.655	NM_030743	Rnf114	ring finger protein 114
chr3_-_117571711	4.626		Snx7	sorting nexin 7
chr17_+_35187325	4.622		Clic1	chloride intracellular channel 1
chr8_-_109417431	4.618	NM_145412	Chtf8	CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr5_-_152453753	4.615	NM_027009	Rfc3	replication factor C (activator 1) 3
chr2_+_74663857	4.600	NM_016804	Mtx2	metaxin 2
chr5_-_115608153	4.599	NM_175403	Mlec	malectin
chr9_+_20449238	4.587		Ubl5	ubiquitin-like 5
chr19_+_55390850	4.585		Vti1a	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
chr5_+_144578646	4.583	NM_013557	Eif2ak1	eukaryotic translation initiation factor 2 alpha kinase 1
chr17_-_71201055	4.573	NM_001164075	Tgif1	TGFB-induced factor homeobox 1
chr7_-_125999115	4.552	NM_001168220	2310008H09Rik	RIKEN cDNA 2310008H09 gene
chr9_-_70269326	4.550	NM_007630	Ccnb2	cyclin B2
chr1_+_58852303	4.530		Casp8	caspase 8
chr19_-_7070522	4.523	NM_026675	Nudt22	nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr1_+_174306656	4.520	NM_026234	Pigm	phosphatidylinositol glycan anchor biosynthesis, class M
chr3_-_130412360	4.520	NM_025509	Ostc	oligosaccharyltransferase complex subunit
chr12_+_70285127	4.518	NM_146035	Mgat2	mannoside acetylglucosaminyltransferase 2
chr19_-_41068625	4.516		Blnk	B-cell linker
chr8_-_26212588	4.506		Plekha2	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr2_+_152673699	4.497	NM_001141975 NM_001141976 NM_001141977 NM_001141978 NM_028109	Tpx2	TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr3_+_95392919	4.478		Golph3l	golgi phosphoprotein 3-like
chr12_+_86311859	4.474	NM_028632	Fcf1	FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chrX_-_35918177	4.459		Cul4b	cullin 4B
chr8_+_87595619	4.451	NM_001039514	Dhps	deoxyhypusine synthase
chr3_-_116415122	4.443		Slc35a3	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chrX_+_102275071	4.443	NM_026312	2610029G23Rik	RIKEN cDNA 2610029G23 gene
chr7_-_52689639	4.437		Ruvbl2	RuvB-like protein 2
chr19_+_9016335	4.425	NM_011842	Mta2	metastasis-associated gene family, member 2
chr9_-_118059168	4.425	NM_026442	Cmc1	COX assembly mitochondrial protein homolog (S. cerevisiae)
chr3_-_116415169	4.420	NM_144902	Slc35a3	solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_-_41670160	4.400	NM_001159565 NM_016890	Dctn3	dynactin 3
chr1_-_133173495	4.392		Ikbke	inhibitor of kappaB kinase epsilon
chr15_+_80064503	4.368	NM_178719	Smcr7l	Smith-Magenis syndrome chromosome region, candidate 7-like (human)
chr13_+_3537514	4.356		Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2
chr19_+_38129500	4.335	NM_028293 NM_001164362 NM_028760	Cep55	centrosomal protein 55
chr19_-_9973901	4.329	NM_016692	Incenp	inner centromere protein
chr9_+_72961223	4.326	NM_198609	Rsl24d1	ribosomal L24 domain containing 1
chr19_+_8810274	4.307	NM_134139	Wdr74	WD repeat domain 74
chr6_-_115758729	4.301	NM_172086	Rpl32	ribosomal protein L32
chr7_-_13623158	4.293	NM_145578	Ube2m	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
chr6_+_108778985	4.283		Edem1	ER degradation enhancer, mannosidase alpha-like 1
chr10_-_117229719	4.279	NM_134010	Nup107	nucleoporin 107
chr5_+_108698687	4.265		Dr1	down-regulator of transcription 1
chr1_+_89110472	4.247	NM_001039170 NM_023314 NM_001039169	Eif4e2	eukaryotic translation initiation factor 4E member 2
chr17_+_35187185	4.241	NM_033444	Clic1	chloride intracellular channel 1
chr19_+_5366812	4.232	NM_027236	Eif1ad	eukaryotic translation initiation factor 1A domain containing
chr6_+_122824491	4.206	NM_026267	Necap1	NECAP endocytosis associated 1
chr11_+_5855721	4.202	NM_019661	Ykt6	YKT6 homolog (S. Cerevisiae)
chr2_+_90780614	4.193	NM_017368 NM_198683	Celf1	CUGBP, Elav-like family member 1
chr7_-_125999511	4.185	NM_001168218 NM_001168219 NM_023197	2310008H09Rik	RIKEN cDNA 2310008H09 gene
chr2_+_172825651	4.153		Rae1	RAE1 RNA export 1 homolog (S. pombe)
chr4_-_140634151	4.137	NM_025383	Necap2	NECAP endocytosis associated 2
chr2_-_25218225	4.132		Uap1l1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr2_-_38860622	4.122	NM_025592	Rpl35	ribosomal protein L35
chr15_+_12251563	4.113		Golph3	golgi phosphoprotein 3
chr15_-_94420206	4.113	NM_008971	Twf1	twinfilin, actin-binding protein, homolog 1 (Drosophila)
chr2_+_118639930	4.113		D2Ertd750e	DNA segment, Chr 2, ERATO Doi 750, expressed
chrX_+_71674576	4.103	NM_001161422	Ikbkg	inhibitor of kappaB kinase gamma
chr15_-_44259852	4.096	NM_001113554 NM_026149	Nudcd1	NudC domain containing 1
chr8_+_114464651	4.085
chr2_+_24200890	4.074	NM_001039701	Il1rn	interleukin 1 receptor antagonist
chr12_+_25183430	4.041	NM_020614	Taf1b	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr19_-_18706181	4.040		Ostf1	osteoclast stimulating factor 1
chr9_+_66793891	4.029	NM_026467	Rps27l	ribosomal protein S27-like
chr7_+_56044372	4.027	NM_028031	Zdhhc13	zinc finger, DHHC domain containing 13
chr17_+_34077595	4.023	NM_020603	Wdr46	WD repeat domain 46
chr3_+_95087190	3.992
chrX_+_71675016	3.981	NM_010547 NM_178590	Ikbkg	inhibitor of kappaB kinase gamma
chr11_-_6167720	3.947	NM_026538	Ddx56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
chr6_+_133985717	3.942	NM_007961	Etv6	ets variant gene 6 (TEL oncogene)
chr2_+_91490266	3.931	NM_001145902	Arhgap1	Rho GTPase activating protein 1
chr19_-_6077175	3.930	NM_001081041	1110014N23Rik	RIKEN cDNA 1110014N23 gene
chr16_-_30587549	3.909	NM_178069	Lsg1	large subunit GTPase 1 homolog (S. cerevisiae)
chr14_+_32308241	3.906	NM_028932	Eaf1	ELL associated factor 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.63	2.93e-62	GO:0044260	cellular macromolecule metabolic process
1.47	9.52e-53	GO:0044237	cellular metabolic process
1.54	2.96e-52	GO:0043170	macromolecule metabolic process
1.43	1.40e-45	GO:0044238	primary metabolic process
1.37	7.73e-43	GO:0008152	metabolic process
1.82	3.38e-40	GO:0044267	cellular protein metabolic process
1.67	9.59e-32	GO:0010467	gene expression
1.64	1.37e-30	GO:0019538	protein metabolic process
1.55	7.33e-29	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59	6.53e-27	GO:0090304	nucleic acid metabolic process
2.46	6.80e-25	GO:0006396	RNA processing
1.48	7.68e-25	GO:0034641	cellular nitrogen compound metabolic process
1.46	2.40e-23	GO:0006807	nitrogen compound metabolic process
2.12	2.43e-22	GO:0015031	protein transport
2.09	7.31e-22	GO:0045184	establishment of protein localization
2.92	1.99e-21	GO:0006412	translation
1.91	6.59e-20	GO:0008104	protein localization
1.55	2.29e-19	GO:0016070	RNA metabolic process
1.47	8.70e-19	GO:0071840	cellular component organization or biogenesis
3.26	1.31e-18	GO:0022613	ribonucleoprotein complex biogenesis
1.15	8.12e-18	GO:0009987	cellular process
3.13	1.21e-17	GO:0071843	cellular component biogenesis at cellular level
1.77	2.45e-17	GO:0033036	macromolecule localization
1.51	6.50e-17	GO:0034645	cellular macromolecule biosynthetic process
1.53	1.22e-16	GO:0071841	cellular component organization or biogenesis at cellular level
1.61	2.62e-16	GO:0043412	macromolecule modification
1.50	3.23e-16	GO:0009059	macromolecule biosynthetic process
2.06	3.99e-15	GO:0046907	intracellular transport
2.28	5.87e-15	GO:0044265	cellular macromolecule catabolic process
1.64	1.32e-14	GO:0006996	organelle organization
2.16	2.68e-14	GO:0009057	macromolecule catabolic process
2.58	5.43e-14	GO:0008380	RNA splicing
1.58	6.13e-14	GO:0006464	protein modification process
2.34	2.47e-13	GO:0016071	mRNA metabolic process
1.39	3.51e-13	GO:0044249	cellular biosynthetic process
1.41	6.22e-13	GO:0016043	cellular component organization
3.31	6.87e-13	GO:0042254	ribosome biogenesis
2.45	1.77e-12	GO:0006397	mRNA processing
1.37	4.29e-12	GO:0009058	biosynthetic process
3.05	1.25e-11	GO:0010498	proteasomal protein catabolic process
3.05	1.25e-11	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.77	2.36e-11	GO:0051649	establishment of localization in cell
1.68	7.53e-11	GO:0051641	cellular localization
3.59	1.19e-10	GO:0006414	translational elongation
2.38	1.65e-10	GO:0006511	ubiquitin-dependent protein catabolic process
2.26	2.24e-10	GO:0030163	protein catabolic process
1.43	3.59e-10	GO:0071842	cellular component organization at cellular level
1.98	4.19e-10	GO:0006259	DNA metabolic process
2.33	6.18e-10	GO:0019941	modification-dependent protein catabolic process
1.66	8.10e-10	GO:0044085	cellular component biogenesis
2.08	8.21e-10	GO:0006974	response to DNA damage stimulus
2.31	9.47e-10	GO:0043632	modification-dependent macromolecule catabolic process
2.27	1.37e-09	GO:0044257	cellular protein catabolic process
2.28	1.41e-09	GO:0051603	proteolysis involved in cellular protein catabolic process
1.85	1.79e-09	GO:0016192	vesicle-mediated transport
2.19	4.87e-09	GO:0070647	protein modification by small protein conjugation or removal
2.28	1.64e-08	GO:0032446	protein modification by small protein conjugation
1.69	1.91e-08	GO:0007049	cell cycle
1.35	2.39e-08	GO:0006810	transport
2.19	2.47e-08	GO:0006281	DNA repair
1.34	3.58e-08	GO:0051234	establishment of localization
1.59	4.02e-08	GO:0044248	cellular catabolic process
3.39	6.62e-08	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.75	8.11e-08	GO:0033554	cellular response to stress
2.95	1.32e-07	GO:0048193	Golgi vesicle transport
3.31	1.51e-07	GO:0051351	positive regulation of ligase activity
2.29	1.95e-07	GO:0034660	ncRNA metabolic process
3.16	2.07e-07	GO:0051438	regulation of ubiquitin-protein ligase activity
1.77	3.32e-07	GO:0022402	cell cycle process
3.09	4.30e-07	GO:0051340	regulation of ligase activity
1.28	6.75e-07	GO:0060255	regulation of macromolecule metabolic process
3.42	7.73e-07	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.21	9.73e-07	GO:0016567	protein ubiquitination
3.46	1.15e-06	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.37	1.18e-06	GO:0051352	negative regulation of ligase activity
3.37	1.18e-06	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.37	1.18e-06	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.26	1.30e-06	GO:0031323	regulation of cellular metabolic process
2.00	1.34e-06	GO:0006886	intracellular protein transport
1.71	1.49e-06	GO:0012501	programmed cell death
2.38	1.53e-06	GO:0034470	ncRNA processing
1.71	1.69e-06	GO:0006915	apoptosis
3.26	1.75e-06	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.01	1.91e-06	GO:0006364	rRNA processing
1.28	1.98e-06	GO:0051179	localization
1.24	2.23e-06	GO:0019222	regulation of metabolic process
1.91	2.50e-06	GO:0000278	mitotic cell cycle
1.66	2.55e-06	GO:0008219	cell death
1.48	2.70e-06	GO:0009056	catabolic process
1.66	2.78e-06	GO:0016265	death
2.78	2.93e-06	GO:0031398	positive regulation of protein ubiquitination
2.91	5.17e-06	GO:0016072	rRNA metabolic process
1.25	6.29e-06	GO:0080090	regulation of primary metabolic process
3.22	8.88e-06	GO:0071826	ribonucleoprotein complex subunit organization
3.29	9.16e-06	GO:0022618	ribonucleoprotein complex assembly
1.79	1.24e-05	GO:0070727	cellular macromolecule localization
1.78	1.78e-05	GO:0034613	cellular protein localization
2.90	2.75e-05	GO:0031397	negative regulation of protein ubiquitination
1.98	6.63e-05	GO:0034622	cellular macromolecular complex assembly
2.37	6.73e-05	GO:0031396	regulation of protein ubiquitination
1.85	1.79e-04	GO:0051301	cell division
1.89	1.80e-04	GO:0034621	cellular macromolecular complex subunit organization
2.87	3.16e-04	GO:0006473	protein acetylation
2.92	5.68e-04	GO:0006475	internal protein amino acid acetylation
2.92	5.68e-04	GO:0018393	internal peptidyl-lysine acetylation
2.88	7.83e-04	GO:0018394	peptidyl-lysine acetylation
3.19	8.25e-04	GO:0006367	transcription initiation from RNA polymerase II promoter
2.94	8.91e-04	GO:0006352	transcription initiation, DNA-dependent
1.59	1.00e-03	GO:0065003	macromolecular complex assembly
1.25	1.16e-03	GO:0010468	regulation of gene expression
1.69	1.19e-03	GO:0051247	positive regulation of protein metabolic process
1.71	1.22e-03	GO:0032270	positive regulation of cellular protein metabolic process
2.89	1.23e-03	GO:0016573	histone acetylation
2.60	1.28e-03	GO:0043543	protein acylation
2.05	2.23e-03	GO:0016570	histone modification
1.68	2.33e-03	GO:0016044	cellular membrane organization
1.55	2.44e-03	GO:0043933	macromolecular complex subunit organization
2.12	2.48e-03	GO:0031400	negative regulation of protein modification process
1.67	2.89e-03	GO:0061024	membrane organization
2.66	2.93e-03	GO:0000209	protein polyubiquitination
3.30	2.99e-03	GO:0006368	transcription elongation from RNA polymerase II promoter
2.82	3.63e-03	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.82	3.63e-03	GO:0000398	nuclear mRNA splicing, via spliceosome
2.02	3.66e-03	GO:0016569	covalent chromatin modification
2.87	4.20e-03	GO:0006302	double-strand break repair
2.78	4.91e-03	GO:0000375	RNA splicing, via transesterification reactions
1.25	5.11e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.30	5.33e-03	GO:0032774	RNA biosynthetic process
1.36	6.36e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.30	6.52e-03	GO:0006351	transcription, DNA-dependent
1.42	7.15e-03	GO:0032268	regulation of cellular protein metabolic process
1.23	7.47e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.72	8.00e-03	GO:0031401	positive regulation of protein modification process
1.44	8.70e-03	GO:0022607	cellular component assembly
3.10	9.33e-03	GO:0006354	transcription elongation, DNA-dependent
1.84	1.02e-02	GO:0032269	negative regulation of cellular protein metabolic process
1.54	1.05e-02	GO:0071844	cellular component assembly at cellular level
2.37	1.15e-02	GO:0018205	peptidyl-lysine modification
2.07	1.33e-02	GO:0006260	DNA replication
3.13	1.45e-02	GO:0061136	regulation of proteasomal protein catabolic process
1.22	1.61e-02	GO:0051171	regulation of nitrogen compound metabolic process
2.66	1.84e-02	GO:0051028	mRNA transport
1.79	1.98e-02	GO:0051248	negative regulation of protein metabolic process
1.70	2.00e-02	GO:0016568	chromatin modification
1.68	2.19e-02	GO:0000279	M phase
3.16	2.26e-02	GO:0000956	nuclear-transcribed mRNA catabolic process
1.33	2.28e-02	GO:0031325	positive regulation of cellular metabolic process
1.60	2.79e-02	GO:0022403	cell cycle phase
2.05	3.05e-02	GO:0006457	protein folding
1.22	3.13e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.57	3.27e-02	GO:0051726	regulation of cell cycle
1.44	3.53e-02	GO:0006508	proteolysis
2.86	3.58e-02	GO:0006402	mRNA catabolic process
1.83	4.22e-02	GO:0030036	actin cytoskeleton organization
2.49	4.27e-02	GO:0050657	nucleic acid transport
2.49	4.27e-02	GO:0050658	RNA transport
2.49	4.27e-02	GO:0051236	establishment of RNA localization

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.42	3.48e-122	GO:0005622	intracellular
1.42	4.64e-118	GO:0044424	intracellular part
1.46	1.33e-100	GO:0043229	intracellular organelle
1.46	3.88e-100	GO:0043226	organelle
1.49	2.76e-91	GO:0043231	intracellular membrane-bounded organelle
1.49	3.01e-91	GO:0043227	membrane-bounded organelle
1.43	4.28e-70	GO:0005737	cytoplasm
1.72	2.43e-68	GO:0044446	intracellular organelle part
1.71	5.78e-67	GO:0044422	organelle part
1.57	3.39e-56	GO:0005634	nucleus
1.75	4.66e-56	GO:0032991	macromolecular complex
1.49	6.11e-49	GO:0044444	cytoplasmic part
2.01	1.30e-47	GO:0044428	nuclear part
1.95	1.36e-40	GO:0031974	membrane-enclosed lumen
1.96	2.73e-40	GO:0070013	intracellular organelle lumen
1.95	4.40e-40	GO:0043233	organelle lumen
2.00	4.16e-37	GO:0031981	nuclear lumen
1.15	1.67e-36	GO:0005623	cell
1.15	1.67e-36	GO:0044464	cell part
1.63	3.60e-32	GO:0043234	protein complex
2.73	1.33e-31	GO:0030529	ribonucleoprotein complex
1.62	1.77e-26	GO:0043228	non-membrane-bounded organelle
1.62	1.77e-26	GO:0043232	intracellular non-membrane-bounded organelle
1.81	1.35e-25	GO:0005829	cytosol
2.01	1.87e-25	GO:0005654	nucleoplasm
3.21	4.67e-17	GO:0005840	ribosome
1.95	1.16e-14	GO:0044451	nucleoplasm part
1.59	1.00e-13	GO:0005739	mitochondrion
2.23	9.44e-13	GO:0005730	nucleolus
1.57	5.00e-10	GO:0031090	organelle membrane
1.65	3.79e-08	GO:0012505	endomembrane system
1.54	7.63e-07	GO:0005794	Golgi apparatus
3.52	1.04e-06	GO:0000502	proteasome complex
2.02	1.23e-06	GO:0044431	Golgi apparatus part
2.69	1.67e-06	GO:0044445	cytosolic part
1.65	4.10e-06	GO:0031967	organelle envelope
2.50	4.53e-06	GO:0005681	spliceosomal complex
2.99	6.23e-06	GO:0071013	catalytic step 2 spliceosome
1.77	8.29e-06	GO:0005768	endosome
1.63	1.02e-05	GO:0031975	envelope
3.12	4.00e-05	GO:0000123	histone acetyltransferase complex
3.61	9.46e-05	GO:0000313	organellar ribosome
3.61	9.46e-05	GO:0005761	mitochondrial ribosome
1.62	1.33e-04	GO:0044429	mitochondrial part
2.30	1.36e-04	GO:0016604	nuclear body
3.40	1.55e-04	GO:0022626	cytosolic ribosome
2.94	1.59e-04	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
1.67	1.80e-04	GO:0005694	chromosome
1.35	2.36e-04	GO:0005856	cytoskeleton
2.11	2.74e-04	GO:0031252	cell leading edge
2.06	3.37e-04	GO:0005635	nuclear envelope
2.96	3.93e-04	GO:0030117	membrane coat
2.96	3.93e-04	GO:0048475	coated membrane
4.33	6.56e-04	GO:0005801	cis-Golgi network
3.13	7.46e-04	GO:0015935	small ribosomal subunit
2.32	1.62e-03	GO:0000151	ubiquitin ligase complex
1.64	1.67e-03	GO:0044427	chromosomal part
2.90	2.95e-03	GO:0016607	nuclear speck
2.26	3.05e-03	GO:0005819	spindle
3.42	4.32e-03	GO:0015934	large ribosomal subunit
3.09	5.83e-03	GO:0005798	Golgi-associated vesicle
1.39	5.84e-03	GO:0044430	cytoskeletal part
3.12	9.11e-03	GO:0000922	spindle pole
2.52	9.44e-03	GO:0001726	ruffle
3.58	9.70e-03	GO:0030120	vesicle coat
1.71	1.16e-02	GO:0015629	actin cytoskeleton
1.98	1.23e-02	GO:0005759	mitochondrial matrix
4.20	1.64e-02	GO:0005839	proteasome core complex
7.99	1.71e-02	GO:0030897	HOPS complex
3.07	2.05e-02	GO:0030118	clathrin coat
1.93	2.28e-02	GO:0000139	Golgi membrane
2.90	2.55e-02	GO:0005643	nuclear pore
2.26	4.60e-02	GO:0030027	lamellipodium

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.19	7.74e-22	GO:0005488	binding
2.10	1.17e-20	GO:0003723	RNA binding
1.29	9.36e-15	GO:0003824	catalytic activity
1.43	1.44e-13	GO:0003676	nucleic acid binding
3.28	6.92e-12	GO:0003735	structural constituent of ribosome
1.43	3.60e-11	GO:0000166	nucleotide binding
1.23	1.71e-10	GO:0005515	protein binding
1.42	4.48e-08	GO:0035639	purine ribonucleoside triphosphate binding
1.42	5.94e-08	GO:0016740	transferase activity
1.41	1.20e-07	GO:0032553	ribonucleotide binding
2.35	1.60e-07	GO:0019787	small conjugating protein ligase activity
1.40	1.76e-07	GO:0032555	purine ribonucleotide binding
1.40	1.78e-07	GO:0017076	purine nucleotide binding
2.22	5.04e-07	GO:0016881	acid-amino acid ligase activity
2.36	6.07e-07	GO:0004842	ubiquitin-protein ligase activity
1.86	1.64e-06	GO:0016874	ligase activity
1.42	2.62e-06	GO:0005524	ATP binding
2.08	3.85e-06	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.41	5.64e-06	GO:0032559	adenyl ribonucleotide binding
1.41	5.72e-06	GO:0030554	adenyl nucleotide binding
1.49	2.92e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.57	1.81e-03	GO:0019904	protein domain specific binding
2.36	2.33e-03	GO:0016779	nucleotidyltransferase activity
2.00	1.17e-02	GO:0008168	methyltransferase activity
3.39	1.42e-02	GO:0003899	DNA-directed RNA polymerase activity
3.39	1.42e-02	GO:0034062	RNA polymerase activity
3.69	2.03e-02	GO:0019843	rRNA binding
1.95	2.18e-02	GO:0016741	transferase activity, transferring one-carbon groups
1.57	2.41e-02	GO:0004674	protein serine/threonine kinase activity
2.71	3.57e-02	GO:0004527	exonuclease activity
2.23	4.05e-02	GO:0008135	translation factor activity, nucleic acid binding
3.99	4.14e-02	GO:0008173	RNA methyltransferase activity
3.99	4.14e-02	GO:0045309	protein phosphorylated amino acid binding