Motif ID: ETS1,2.p2

Z-value: 2.832


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
Ets1 23871 E26 avian leukemia oncogene 1, 5' domain
Ets2 23872 E26 avian leukemia oncogene 2, 3' domain

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ets1chr9_+_325036000.365.0e-07Click!
Ets2chr16_+_95924069-0.295.6e-05Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_75576599 49.547 Lcp1
lymphocyte cytosolic protein 1
chr14_-_33998251 49.006 NM_001146022
Wdfy4
WD repeat and FYVE domain containing 4
chr11_-_6420904 45.601 Myo1g
myosin IG
chr15_-_66392539 45.482 NM_172514
Tmem71
transmembrane protein 71
chr11_+_83037951 44.413 AI662270
expressed sequence AI662270
chr11_-_6420931 42.994 NM_178440
Myo1g
myosin IG
chr16_-_19983049 39.081 NM_183390
Klhl6
kelch-like 6 (Drosophila)
chr16_-_75909440 36.767 NM_023380
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr4_+_3605207 35.864 NM_001111096
NM_010747
Lyn

Yamaguchi sarcoma viral (v-yes-1) oncogene homolog

chr1_-_133096633 33.819 Rassf5
Ras association (RalGDS/AF-6) domain family member 5
chr6_-_87483228 31.968 NM_001037727
Arhgap25
Rho GTPase activating protein 25
chr8_+_87225355 31.774 NM_008535
Lyl1
lymphoblastomic leukemia 1
chr4_-_63064369 31.702 NM_001045514
Akna
AT-hook transcription factor
chr16_+_36935029 30.880 NM_008225
Hcls1
hematopoietic cell specific Lyn substrate 1
chr7_-_52494453 30.220 Cd37
CD37 antigen
chrX_+_45499599 29.128 NM_028773
Sash3
SAM and SH3 domain containing 3
chr1_+_173319048 28.347 NM_001005508
Arhgap30
Rho GTPase activating protein 30
chr19_-_4190836 28.227 NM_178650
Tbc1d10c
TBC1 domain family, member 10c
chr6_-_48658182 28.221 Gimap6
GTPase, IMAP family member 6
chr15_+_78427476 28.208 NM_028195
Cyth4
cytohesin 4
chr6_-_48658211 27.575 NM_153175
Gimap6
GTPase, IMAP family member 6
chr1_+_34529567 27.387 Ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr15_-_5058532 27.377 NM_001163138
Card6
caspase recruitment domain family, member 6
chr10_+_76993060 26.725 NM_008404
Itgb2
integrin beta 2
chr7_+_134439804 26.689 NM_008400
Itgal
integrin alpha L
chr5_-_141476549 25.885 NM_175362
Card11
caspase recruitment domain family, member 11
chr1_+_175350728 24.747 NM_001013779
Aim2
absent in melanoma 2
chr14_+_51748742 24.710 NM_030098
Rnase6
ribonuclease, RNase A family, 6
chr3_-_106592919 24.556 NM_007651
Cd53
CD53 antigen
chr6_-_87446228 24.245 NM_175476
Arhgap25
Rho GTPase activating protein 25
chr13_-_37142112 23.632 NM_001166391
F13a1
coagulation factor XIII, A1 subunit
chr10_+_26492282 23.186 NM_176837
Arhgap18
Rho GTPase activating protein 18
chr13_-_100972022 22.011 NM_001126182
NM_010872
Naip2

NLR family, apoptosis inhibitory protein 2

chr5_+_34886013 21.968 NM_001145858
Sh3bp2
SH3-domain binding protein 2
chr7_-_90803895 21.723 Il16
interleukin 16
chr11_-_114795651 21.537 NM_199221
Cd300lb
CD300 antigen like family member B
chr19_+_4154645 21.425 NM_016933
Ptprcap
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr7_-_135561641 21.402 NM_026418
Rgs10
regulator of G-protein signalling 10
chr4_+_130469187 21.289 NM_010686
Laptm5
lysosomal-associated protein transmembrane 5
chr17_+_35331446 21.053 NM_008518
Ltb
lymphotoxin B
chr7_-_133512962 19.904 NM_010689
Lat
linker for activation of T cells
chrX_-_7667574 19.841 NM_009515
Was
Wiskott-Aldrich syndrome homolog (human)
chr15_-_9459496 19.784 Il7r
interleukin 7 receptor
chr11_-_106243873 19.777 NM_010494
Icam2
intercellular adhesion molecule 2
chr15_-_9459612 19.722 NM_008372
Il7r
interleukin 7 receptor
chr6_+_145070255 19.660 NM_008511
Lrmp
lymphoid-restricted membrane protein
chr8_-_124956759 19.633 NM_007806
Cyba
cytochrome b-245, alpha polypeptide
chr8_+_87225390 19.592 Lyl1
lymphoblastomic leukemia 1
chr7_-_31204764 19.502 NM_011827
Hcst
hematopoietic cell signal transducer
chr3_+_90472990 19.298 NM_013650
S100a8
S100 calcium binding protein A8 (calgranulin A)
chr6_+_68375560 18.947 Igkv16-104
immunoglobulin kappa variable 16-104
chr1_+_154654953 18.684 NM_010877
Ncf2
neutrophil cytosolic factor 2
chr10_-_116719364 18.405 Lyz2
lysozyme 2
chr11_+_62389367 18.381 Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr17_+_57418517 18.272 NM_001163815
NM_001163816
NM_011691
Vav1


vav 1 oncogene


chr1_+_133763777 18.200 NM_144875
Rab7l1
RAB7, member RAS oncogene family-like 1
chr10_+_126760748 18.090 NM_146011
Arhgap9
Rho GTPase activating protein 9
chr9_+_88851757 18.090 NM_009742
Bcl2a1a
B-cell leukemia/lymphoma 2 related protein A1a
chr14_-_121778399 18.058 NM_145465
Stk24
serine/threonine kinase 24 (STE20 homolog, yeast)
chr13_-_59924405 17.896 NM_153538
Zcchc6
zinc finger, CCHC domain containing 6
chr5_-_109985883 17.832 Crlf2
cytokine receptor-like factor 2
chr10_-_116719183 17.681 NM_017372
Lyz2
lysozyme 2
chr15_-_66644127 17.680 NM_009192
Sla
src-like adaptor
chr11_+_53583927 17.558 NM_001159396
Irf1
interferon regulatory factor 1
chr4_-_43467398 17.451 NM_001110320
NM_001110321
NM_001110322
NM_007654
Cd72



CD72 antigen



chr5_-_141476424 17.026 Card11
caspase recruitment domain family, member 11
chr8_+_74743673 16.969 Fam32a
family with sequence similarity 32, member A
chr12_-_32893074 16.844 NM_001146201
NM_020272
NM_001146200
Pik3cg


phosphoinositide-3-kinase, catalytic, gamma polypeptide


chr3_-_90499611 16.585 NM_009114
S100a9
S100 calcium binding protein A9 (calgranulin B)
chr7_-_111656285 16.403 NM_001167828
NM_199146
Trim30a
Trim30d

tripartite motif-containing 30A
tripartite motif-containing 30D

chr15_-_66644199 16.336 Sla
src-like adaptor
chr9_+_114640266 16.331 NM_026036
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr6_-_124688630 16.038 NM_001077705
Ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr6_-_38304508 16.032 Zc3hav1
zinc finger CCCH type, antiviral 1
chr2_-_25052245 15.762 NM_146115
A830007P12Rik
RIKEN cDNA A830007P12 gene
chr2_+_24242134 15.739 Psd4
pleckstrin and Sec7 domain containing 4
chr12_+_113998865 15.728 NM_178911
Pld4
phospholipase D family, member 4
chr9_+_89094190 15.686 Bcl2a1a
B-cell leukemia/lymphoma 2 related protein A1a
chr19_-_41406744 15.619 Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr17_+_48455465 15.520 NM_177083
B430306N03Rik
RIKEN cDNA B430306N03 gene
chr19_+_11592938 15.430 NM_027209
Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr1_-_133173495 15.428 Ikbke
inhibitor of kappaB kinase epsilon
chr6_+_48689045 15.372 NM_008376
NM_175860
Gimap1

GTPase, IMAP family member 1

chr7_-_4014717 15.337 NM_001113474
NM_178611
Lair1

leukocyte-associated Ig-like receptor 1

chr15_-_94373918 15.280 NM_172437
Pus7l
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr12_+_105452740 15.091 NM_009251
NM_001168294
NM_001168295
NM_001033335
Serpina3g
Serpina3f


Serpina3h
serine (or cysteine) peptidase inhibitor, clade A, member 3G
serine (or cysteine) peptidase inhibitor, clade A, member 3F


serine (or cysteine) peptidase inhibitor, clade A, member 3H
chr7_-_148286422 15.087 NM_023059
Sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr7_-_31827099 15.024 NM_008761
Fxyd5
FXYD domain-containing ion transport regulator 5
chr8_+_90812964 14.999 NM_001037723
Adcy7
adenylate cyclase 7
chr19_-_11340591 14.978 NM_007641
Ms4a1
membrane-spanning 4-domains, subfamily A, member 1
chr13_-_104710374 14.955 NM_001005868
NM_021563
Erbb2ip

Erbb2 interacting protein

chr14_-_121778143 14.920 Stk24
serine/threonine kinase 24 (STE20 homolog, yeast)
chr10_+_126602182 14.912 NM_008080
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr2_-_73291933 14.871 Wipf1
WAS/WASL interacting protein family, member 1
chr2_+_167757867 14.867 Ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr7_+_25688004 14.784 NM_001130150
NM_001130151
NM_001130153
NM_008488
Arhgef1



Rho guanine nucleotide exchange factor (GEF) 1



chr6_+_129347314 14.697 NM_019985
Clec1b
C-type lectin domain family 1, member b
chr15_-_102062331 14.648 NM_013566
Itgb7
integrin beta 7
chr7_+_134234872 14.620 NM_178901
AI467606
expressed sequence AI467606
chr5_+_86500770 14.595 NM_019992
Stap1
signal transducing adaptor family member 1
chr2_+_103798150 14.537 NM_001142337
Lmo2
LIM domain only 2
chr12_+_105474449 14.408 Serpina3g
serine (or cysteine) peptidase inhibitor, clade A, member 3G
chr2_-_25052129 14.322 A830007P12Rik
RIKEN cDNA A830007P12 gene
chr7_-_111613624 14.320 NM_009099
Trim30a
tripartite motif-containing 30A
chr9_+_106105422 14.311 NM_011876
Twf2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr7_+_25155279 14.219 NM_001163510
NM_008433
Kcnn4

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

chr14_-_55725370 14.074 NM_007455
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chr5_-_105482574 14.038 NM_029509
Gbp8
guanylate-binding protein 8
chr2_+_43604343 14.012 NM_153820
NM_001025377
Arhgap15

Rho GTPase activating protein 15

chr8_+_74743620 13.962 NM_026455
Fam32a
family with sequence similarity 32, member A
chr1_+_175560938 13.866 NM_175026
Pyhin1
pyrin and HIN domain family, member 1
chr5_-_135090819 13.771 NM_020044
NM_022964
Lat2

linker for activation of T cells family, member 2

chr7_-_31826775 13.764 NM_001111073
Fxyd5
FXYD domain-containing ion transport regulator 5
chr7_+_133728451 13.484 Apobr
apolipoprotein B receptor
chr6_+_125502979 13.442 NM_011708
Vwf
Von Willebrand factor homolog
chr7_+_29767872 13.433 NM_008279
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr9_-_88626613 13.395 NM_007536
Bcl2a1d
B-cell leukemia/lymphoma 2 related protein A1d
chr1_+_121423003 13.344 Tmem185b
transmembrane protein 185B
chrX_+_104479684 13.157 NM_001177782
Gpr174
G protein-coupled receptor 174
chr8_+_120022149 13.052 NM_172285
Plcg2
phospholipase C, gamma 2
chr2_+_127161893 12.907 NM_010090
Dusp2
dual specificity phosphatase 2
chr7_-_80703275 12.785 1810026B05Rik
RIKEN cDNA 1810026B05 gene
chr9_+_55937776 12.764 NM_011193
Pstpip1
proline-serine-threonine phosphatase-interacting protein 1
chr7_+_25682507 12.704 NM_007655
Cd79a
CD79A antigen (immunoglobulin-associated alpha)
chr1_+_58859345 12.698 NM_001080126
Casp8
caspase 8
chr17_-_36248574 12.695 H2-T23
C920025E04Rik
histocompatibility 2, T region locus 23
RIKEN cDNA C920025E04 gene
chr12_-_70576533 12.635 5830428M24Rik
RIKEN cDNA 5830428M24 gene
chr19_-_41459518 12.634 NM_031376
Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr19_-_5661634 12.582 Sipa1
signal-induced proliferation associated gene 1
chr7_-_16844541 12.526 C5ar1
complement component 5a receptor 1
chr3_-_137644466 12.512 NM_011932
Dapp1
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
chr2_+_3341402 12.451 NM_001110214
NM_146114
NM_175683
Dclre1c


DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)


chr11_-_99016390 12.383 NM_007719
Ccr7
chemokine (C-C motif) receptor 7
chrX_-_70327816 12.376 NM_001081642
Xlr4a
X-linked lymphocyte-regulated 4A
chr2_+_150396150 12.375 NM_009977
Cst7
cystatin F (leukocystatin)
chr8_+_72332573 12.356 NM_198101
Gmip
Gem-interacting protein
chr7_+_25155455 12.354 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr4_-_129250806 12.324 NM_001162433
Lck
lymphocyte protein tyrosine kinase
chr13_+_52678541 12.301 Sykb
spleen tyrosine kinase
chr11_+_87607285 12.296 NM_010824
Mpo
myeloperoxidase
chr15_-_102062309 12.284 Itgb7
integrin beta 7
chr10_+_60760581 12.277 NM_011073
Prf1
perforin 1 (pore forming protein)
chr11_+_53583515 12.259 NM_001159393
NM_008390
Irf1

interferon regulatory factor 1

chr1_-_54983211 12.109 NM_001081433
Ankrd44
ankyrin repeat domain 44
chr7_-_26324847 12.104 NM_001113368
NM_001113369
NM_007543
Ceacam2


carcinoembryonic antigen-related cell adhesion molecule 2


chr7_+_133728483 12.096 NM_138310
Apobr
apolipoprotein B receptor
chr8_-_122334083 12.043 Cotl1
coactosin-like 1 (Dictyostelium)
chr7_+_142843598 12.008 Ptpre
protein tyrosine phosphatase, receptor type, E
chr7_-_135137189 12.003 Pycard
PYD and CARD domain containing
chr19_-_41069024 11.999 NM_008528
Blnk
B-cell linker
chr1_+_173770709 11.806 NM_013489
Cd84
CD84 antigen
chr19_-_61302538 11.742 Csf2ra
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr2_+_22629846 11.706 NM_019456
Apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr10_-_79565387 11.676 NM_183426
Sbno2
strawberry notch homolog 2 (Drosophila)
chr18_-_61336629 11.666 NM_178277
NM_134134
Hmgxb3

HMG box domain containing 3

chr13_-_39052356 11.643 NM_001170430
NM_134060
Slc35b3

solute carrier family 35, member B3

chr9_+_89094110 11.626 NM_007534
Bcl2a1a
Bcl2a1b
B-cell leukemia/lymphoma 2 related protein A1a
B-cell leukemia/lymphoma 2 related protein A1b
chr10_+_41196119 11.576 NM_001164433
NM_138315
Mical1

microtubule associated monoxygenase, calponin and LIM domain containing 1

chr7_+_111392968 11.544 NM_030684
Trim34a
tripartite motif-containing 34A
chr10_+_114822009 11.472 NM_001033261
Zfc3h1
zinc finger, C3H1-type containing
chr11_+_95703981 11.470 NM_001038664
Gngt2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr11_+_32433265 11.430 NM_009288
Stk10
serine/threonine kinase 10
chrX_+_139115908 11.400 NM_177592
Tmem164
transmembrane protein 164
chr6_-_129422702 11.370 NM_020008
Clec7a
C-type lectin domain family 7, member a
chr9_+_21330620 11.350 NM_001198794
NM_206536
AB124611

cDNA sequence AB124611

chr1_+_16678513 11.349 Ly96
lymphocyte antigen 96
chr1_+_133535033 11.319 Ctse
cathepsin E
chr1_+_87546558 11.295 NM_013673
Sp100
nuclear antigen Sp100
chr2_-_31939210 11.280 NM_175511
Fam78a
family with sequence similarity 78, member A
chr9_-_88626434 11.248 Bcl2a1d
B-cell leukemia/lymphoma 2 related protein A1d
chr9_+_123387818 11.194 NM_013860
Limd1
LIM domains containing 1
chr1_-_182186429 11.160 NM_001128605
Psen2
presenilin 2
chr11_+_62387987 11.130 NM_011706
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr7_-_16872094 11.100 NM_001136471
Ccdc9
coiled-coil domain containing 9
chr6_+_70165393 11.074 Igk-V28
Igkv6-23
LOC672450
immunoglobulin kappa chain variable 28 (V28)
immunoglobulin kappa variable 6-23
V(kappa) gene product
chr1_+_58852471 11.069 Casp8
caspase 8
chr11_-_114995194 11.065 NM_001169153
NM_145634
Cd300lf

CD300 antigen like family member F

chr14_+_70499874 11.026 NM_021328
Bin3
bridging integrator 3
chr18_-_84758848 10.980 NM_001033341
Zfp407
zinc finger protein 407
chr11_+_62388079 10.919 Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr1_+_58852217 10.777 NM_009812
Casp8
caspase 8
chr7_+_129432810 10.771 Prkcb
protein kinase C, beta
chr2_-_72817058 10.754 Sp3
trans-acting transcription factor 3
chr15_+_94374097 10.723 Irak4
interleukin-1 receptor-associated kinase 4
chr9_-_106101269 10.681 NM_198931
Ppm1m
protein phosphatase 1M
chr8_-_91159932 10.674 NM_027840
Snx20
sorting nexin 20
chr3_-_75360749 10.650 Pdcd10
programmed cell death 10
chr9_-_57492978 10.592 NM_007783
Csk
c-src tyrosine kinase
chr13_-_39052743 10.557 NM_001170431
Slc35b3
solute carrier family 35, member B3
chr11_+_87607531 10.551 Mpo
myeloperoxidase
chr12_+_103521355 10.543 Rin3
Ras and Rab interactor 3
chr4_-_129235583 10.541 NM_001162432
NM_010693
Lck

lymphocyte protein tyrosine kinase

chr17_+_29497858 10.514 NM_001159538
NM_013710
Fgd2

FYVE, RhoGEF and PH domain containing 2

chr10_-_116729893 10.488 NM_013590
Lyz1
lysozyme 1
chr7_-_50788445 10.467 Cd33
CD33 antigen
chr2_+_90936845 10.386 NM_011355
Sfpi1
SFFV proviral integration 1
chr1_-_54983132 10.356 Ankrd44
ankyrin repeat domain 44
chr2_-_148269170 10.326 NM_010740
Cd93
CD93 antigen
chr7_-_134040741 10.309 Tmem219
transmembrane protein 219
chr12_+_3235481 10.268 1700012B15Rik
RIKEN cDNA 1700012B15 gene

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.81 1.39e-15 GO:0002376 immune system process
2.42 3.17e-12 GO:0045321 leukocyte activation
2.30 5.19e-12 GO:0001775 cell activation
2.53 1.95e-11 GO:0046649 lymphocyte activation
1.23 2.66e-08 GO:0044260 cellular macromolecule metabolic process
1.32 4.17e-08 GO:0090304 nucleic acid metabolic process
1.21 4.57e-08 GO:0043170 macromolecule metabolic process
1.94 1.20e-07 GO:0006955 immune response
1.26 2.65e-07 GO:0080090 regulation of primary metabolic process
1.97 4.35e-07 GO:0050776 regulation of immune response
1.89 4.87e-07 GO:0002684 positive regulation of immune system process
1.33 7.32e-07 GO:0016070 RNA metabolic process
1.26 7.69e-07 GO:0060255 regulation of macromolecule metabolic process
1.70 9.04e-07 GO:0002682 regulation of immune system process
1.23 1.09e-06 GO:0019222 regulation of metabolic process
3.05 1.58e-06 GO:0042113 B cell activation
1.25 1.73e-06 GO:0031323 regulation of cellular metabolic process
1.27 2.18e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 2.57e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.36 3.65e-06 GO:0002521 leukocyte differentiation
1.29 3.80e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.30 3.88e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.24 8.76e-06 GO:0034641 cellular nitrogen compound metabolic process
2.03 1.74e-05 GO:0050778 positive regulation of immune response
1.23 2.34e-05 GO:0006807 nitrogen compound metabolic process
1.15 3.27e-05 GO:0044238 primary metabolic process
1.26 4.94e-05 GO:0009889 regulation of biosynthetic process
3.14 8.78e-05 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.41 1.04e-04 GO:0030098 lymphocyte differentiation
2.30 1.18e-04 GO:0002764 immune response-regulating signaling pathway
1.26 1.21e-04 GO:0010468 regulation of gene expression
1.35 1.21e-04 GO:0048583 regulation of response to stimulus
1.27 1.23e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
3.17 1.24e-04 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.26 1.34e-04 GO:0031326 regulation of cellular biosynthetic process
2.31 1.38e-04 GO:0002757 immune response-activating signal transduction
1.27 2.55e-04 GO:0051252 regulation of RNA metabolic process
1.26 2.65e-04 GO:0010467 gene expression
1.84 4.65e-04 GO:0030097 hemopoiesis
1.27 5.57e-04 GO:0006355 regulation of transcription, DNA-dependent
2.11 6.20e-04 GO:0002253 activation of immune response
1.32 6.22e-04 GO:0032774 RNA biosynthetic process
1.93 6.36e-04 GO:0002694 regulation of leukocyte activation
1.31 7.58e-04 GO:0006351 transcription, DNA-dependent
1.89 1.36e-03 GO:0050865 regulation of cell activation
1.54 1.48e-03 GO:0006915 apoptosis
1.51 1.55e-03 GO:0016265 death
3.15 1.72e-03 GO:0050851 antigen receptor-mediated signaling pathway
2.20 1.73e-03 GO:0042110 T cell activation
1.12 1.83e-03 GO:0008152 metabolic process
1.72 1.90e-03 GO:0002520 immune system development
1.52 2.36e-03 GO:0012501 programmed cell death
1.13 2.37e-03 GO:0044237 cellular metabolic process
1.50 2.39e-03 GO:0008219 cell death
1.72 3.66e-03 GO:0048534 hemopoietic or lymphoid organ development
1.24 3.77e-03 GO:0009059 macromolecule biosynthetic process
3.18 5.22e-03 GO:0030183 B cell differentiation
1.24 5.35e-03 GO:0034645 cellular macromolecule biosynthetic process
2.05 7.30e-03 GO:0002252 immune effector process
1.78 8.59e-03 GO:0001817 regulation of cytokine production
1.88 9.41e-03 GO:0051249 regulation of lymphocyte activation
2.33 1.16e-02 GO:0002703 regulation of leukocyte mediated immunity
1.80 1.25e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.83 2.32e-02 GO:0046578 regulation of Ras protein signal transduction
2.42 3.14e-02 GO:0042035 regulation of cytokine biosynthetic process
2.71 3.15e-02 GO:0002263 cell activation involved in immune response
2.71 3.15e-02 GO:0002366 leukocyte activation involved in immune response
2.37 3.49e-02 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
2.21 3.63e-02 GO:0035023 regulation of Rho protein signal transduction
1.99 3.85e-02 GO:0050863 regulation of T cell activation
2.34 4.46e-02 GO:0002706 regulation of lymphocyte mediated immunity

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.23 2.40e-10 GO:0005634 nucleus
1.12 8.25e-10 GO:0005622 intracellular
1.11 3.39e-08 GO:0044424 intracellular part
1.13 2.95e-06 GO:0043227 membrane-bounded organelle
1.13 4.55e-06 GO:0043231 intracellular membrane-bounded organelle
1.11 1.63e-05 GO:0043229 intracellular organelle
1.11 1.79e-05 GO:0043226 organelle
1.25 1.14e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.11 6.60e-08 GO:0005488 binding
1.28 3.12e-06 GO:0003676 nucleic acid binding
1.14 1.13e-03 GO:0005515 protein binding
1.28 1.68e-03 GO:0003677 DNA binding
1.55 2.27e-02 GO:0030695 GTPase regulator activity
1.69 2.57e-02 GO:0005083 small GTPase regulator activity