Motif ID: GFI1.p2

Z-value: 2.190


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
Gfi1 14581 growth factor independent 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gfi1chr5_-_1081533370.121.1e-01Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_86479405 71.292 NM_024184
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr3_-_27052733 52.685 NM_001177625
NM_007900
Ect2

ect2 oncogene

chr14_-_68333666 50.852 NM_001110162
Cdca2
cell division cycle associated 2
chr3_-_27052794 45.522 NM_001177626
Ect2
ect2 oncogene
chr11_-_98885428 41.405 NM_011623
Top2a
topoisomerase (DNA) II alpha
chr14_-_68333897 41.092 NM_175384
Cdca2
cell division cycle associated 2
chr2_+_164595415 36.748 NM_026785
Ube2c
ubiquitin-conjugating enzyme E2C
chr16_-_18811669 36.287 NM_001161623
Cdc45
cell division cycle 45 homolog (S. cerevisiae)
chr2_+_164595447 36.161 Ube2c
ubiquitin-conjugating enzyme E2C
chr2_-_172195998 35.553 NM_011497
Aurka
aurora kinase A
chr2_+_164595389 35.147 Ube2c
ubiquitin-conjugating enzyme E2C
chr4_-_124614072 31.802 NM_026560
Cdca8
cell division cycle associated 8
chr13_+_51740600 29.980 NM_025415
Cks2
CDC28 protein kinase regulatory subunit 2
chr13_+_51740804 29.448 Cks2
CDC28 protein kinase regulatory subunit 2
chr11_+_86922732 26.792 NM_025377
Fam33a
family with sequence similarity 33, member A
chr13_+_105019053 25.543 Cenpk
centromere protein K
chr17_-_34027575 25.005 NM_001195298
Kifc1
kinesin family member C1
chr6_-_125141525 25.002 NM_146171
Ncapd2
non-SMC condensin I complex, subunit D2
chr13_+_105019025 24.810 NM_181061
Cenpk
centromere protein K
chr16_-_15637390 23.861 NM_008565
Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr17_-_34027488 23.279 Kifc1
kinesin family member C1
chr17_-_34027547 22.903 Kifc1
kinesin family member C1
chr3_+_159158396 20.627 NM_001172092
NM_001172093
NM_029523
Depdc1a


DEP domain containing 1a


chr5_+_124199713 20.441 NM_001042421
Kntc1
kinetochore associated 1
chr18_+_34784277 18.279 NM_001166407
Kif20a
kinesin family member 20A
chr15_-_99481964 18.094 NM_012025
Racgap1
Rac GTPase-activating protein 1
chr18_+_34784589 18.007 NM_009004
NM_001166406
Kif20a

kinesin family member 20A

chr8_+_59990639 17.539 NM_008252
Hmgb2
high mobility group box 2
chr10_-_93052348 17.485 NM_027246
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr16_-_18812064 17.035 NM_009862
Cdc45
cell division cycle 45 homolog (S. cerevisiae)
chr7_-_142908061 16.997 NM_001081117
Mki67
antigen identified by monoclonal antibody Ki 67
chr7_-_56136965 16.612 E2f8
E2F transcription factor 8
chr14_+_47380287 16.402 Cdkn3
cyclin-dependent kinase inhibitor 3
chr5_+_34001199 16.146 Tacc3
transforming, acidic coiled-coil containing protein 3
chr18_+_67959756 16.124 NM_027556
Cep192
centrosomal protein 192
chr11_-_86922163 15.992 NM_175563
Prr11
proline rich 11
chr13_+_105019467 15.706 NM_021790
Cenpk
centromere protein K
chr9_+_83728331 14.864 Ttk
Ttk protein kinase
chr9_+_83728295 14.599 NM_001110265
NM_009445
Ttk

Ttk protein kinase

chr10_-_68815606 14.517 NM_007659
Cdk1
cyclin-dependent kinase 1
chr9_-_21564742 14.200 Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr14_+_47380215 14.056 NM_028222
Cdkn3
cyclin-dependent kinase inhibitor 3
chr11_-_106860750 14.019 Kpna2
karyopherin (importin) alpha 2
chr7_+_129302998 13.857 Plk1
polo-like kinase 1 (Drosophila)
chr1_+_193645351 13.849 NM_010892
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr15_+_102126686 13.779 NM_001014976
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr15_+_102126735 13.765 Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr13_+_21902235 13.549 NM_178185
NM_001177544
Hist1h2ah
Hist1h2ap
Hist1h2ai
Hist1h2ao
histone cluster 1, H2ah
histone cluster 1, H2ap
histone cluster 1, H2ai
histone cluster 1, H2ao
chr19_-_9973901 13.274 NM_016692
Incenp
inner centromere protein
chr7_-_134185894 13.269 Kif22
kinesin family member 22
chr11_-_115885714 13.238 NM_008211
H3f3b
H3 histone, family 3B
chr7_-_134185928 13.192 NM_145588
Kif22
kinesin family member 22
chr10_+_4541138 13.142 Fbxo5
F-box protein 5
chr8_-_123112925 12.956 Gins2
GINS complex subunit 2 (Psf2 homolog)
chr3_+_94217197 12.905 NM_028307
Tdrkh
tudor and KH domain containing protein
chr5_+_34000745 12.857 NM_001040435
Tacc3
transforming, acidic coiled-coil containing protein 3
chr7_-_100022714 12.807 NM_001080995
4632434I11Rik
RIKEN cDNA 4632434I11 gene
chr13_-_21925343 12.650 NM_178185
NM_001177544
Hist1h2ah
Hist1h2ap
Hist1h2ai
Hist1h2ao
histone cluster 1, H2ah
histone cluster 1, H2ap
histone cluster 1, H2ai
histone cluster 1, H2ao
chr11_+_71855939 12.620 NM_144526
Fam64a
family with sequence similarity 64, member A
chr7_+_129303029 12.541 Plk1
polo-like kinase 1 (Drosophila)
chr13_-_23663006 12.536 NM_178187
Hist1h2ae
histone cluster 1, H2ae
chr11_-_102786433 12.482 NM_197959
Kif18b
kinesin family member 18B
chr13_-_21845695 12.342 NM_178183
Hist1h2ak
histone cluster 1, H2ak
chr10_+_4541075 12.341 NM_025995
Fbxo5
F-box protein 5
chr11_-_97048933 12.295 Kpnb1
karyopherin (importin) beta 1
chr1_+_136859153 12.198 NM_026024
Ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr11_-_102786403 12.048 Kif18b
kinesin family member 18B
chr17_-_24388262 11.995 NM_007634
Ccnf
cyclin F
chr9_+_44142772 11.977 NM_010436
H2afx
H2A histone family, member X
chr11_+_98769162 11.892 NM_001025779
Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr11_+_103828032 11.802 Arf2
ADP-ribosylation factor 2
chr3_+_108186721 11.798 NM_001190161
NM_019976
Psrc1

proline/serine-rich coiled-coil 1

chr1_+_136859183 11.734 Ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr9_-_21564723 11.694 NM_026282
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr11_-_97049143 11.675 Kpnb1
karyopherin (importin) beta 1
chr2_-_127657532 11.662 NM_001113179
NM_009772
Bub1

budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)

chr17_+_88071837 11.346 NM_008628
Msh2
mutS homolog 2 (E. coli)
chr3_+_79433000 11.292 NM_029482
4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr6_+_116214215 11.268 NM_001081317
Anubl1
AN1, ubiquitin-like, homolog (Xenopus laevis)
chr2_-_129122892 11.257 NM_181589
Ckap2l
cytoskeleton associated protein 2-like
chr3_+_134875526 11.197 NM_173762
Cenpe
centromere protein E
chr4_+_114672849 11.069 Stil
Scl/Tal1 interrupting locus
chr4_+_132324212 11.040 NM_011284
Rpa2
replication protein A2
chr2_+_118639738 10.867 NM_026412
D2Ertd750e
DNA segment, Chr 2, ERATO Doi 750, expressed
chr17_+_56442759 10.861 NM_001111079
NM_010931
Uhrf1

ubiquitin-like, containing PHD and RING finger domains, 1

chr4_+_114672722 10.857 NM_009185
Stil
Scl/Tal1 interrupting locus
chr11_-_100956699 10.813 NM_008949
Psmc3ip
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr14_-_66452720 10.748 NM_028039
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr15_-_98507886 10.640 NM_172612
Rnd1
Rho family GTPase 1
chr6_+_124780193 10.396 NM_013538
Cdca3
cell division cycle associated 3
chr6_-_126889539 10.381 NM_009013
Rad51ap1
RAD51 associated protein 1
chr10_-_87609629 10.258 NM_029249
4930547N16Rik
RIKEN cDNA 4930547N16 gene
chr10_+_87609768 10.230 NM_028334
Nup37
nucleoporin 37
chr2_+_152673699 10.218 NM_001141975
NM_001141976
NM_001141977
NM_001141978
NM_028109
Tpx2




TPX2, microtubule-associated protein homolog (Xenopus laevis)




chr11_-_97049185 10.124 NM_008379
Kpnb1
karyopherin (importin) beta 1
chr4_+_98590457 10.107 NM_146144
Usp1
ubiquitin specific peptidase 1
chr10_+_87609736 10.090 NM_027191
Nup37
nucleoporin 37
chrX_-_90877453 10.046 NM_008892
Pola1
polymerase (DNA directed), alpha 1
chr13_-_21879086 10.024 NM_178184
Hist1h2an
histone cluster 1, H2an
chr14_-_99498905 9.989 NM_028315
Dis3
DIS3 mitotic control homolog (S. cerevisiae)
chr11_-_106860803 9.965 NM_010655
Kpna2
karyopherin (importin) alpha 2
chr11_+_98769122 9.910 Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr10_+_20067606 9.846 NM_027930
Fam54a
family with sequence similarity 54, member A
chr7_-_87679873 9.751 NM_007550
NM_001042527
Blm

Bloom syndrome, RecQ helicase-like

chr17_+_27693518 9.723 NM_001166476
NM_001166477
NM_001025427
NM_001039356
NM_001166535
NM_001166536
NM_001166539
NM_001166540
NM_001166541
NM_001166542
NM_001166543
NM_001166544
NM_001166545
NM_001166546
NM_001166537
NM_016660
Hmga1-rs1

Hmga1













high mobility group AT-hook I, related sequence 1

high mobility group AT-hook 1













chr2_+_166731527 9.678 NM_023565
Cse1l
chromosome segregation 1-like (S. cerevisiae)
chr3_-_98143778 9.574 NM_016966
Phgdh
3-phosphoglycerate dehydrogenase
chr13_+_109106530 9.487 NM_178683
Depdc1b
DEP domain containing 1B
chr14_-_48038081 9.461 NM_001145949
NM_144553
Dlgap5

discs, large (Drosophila) homolog-associated protein 5

chr5_+_116295259 9.327 Cit
citron
chr6_+_124780226 9.286 Cdca3
cell division cycle associated 3
chr7_+_129302950 9.248 NM_011121
Plk1
polo-like kinase 1 (Drosophila)
chr1_+_133424461 9.228 Fam72a
family with sequence similarity 72, member A
chr12_+_114394594 9.160 NM_134041
4930427A07Rik
RIKEN cDNA 4930427A07 gene
chr11_+_98769464 9.063 NM_011799
Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr11_+_103828184 9.019 NM_007477
Arf2
ADP-ribosylation factor 2
chr6_-_47544925 8.991 NM_001146689
NM_007971
Ezh2

enhancer of zeste homolog 2 (Drosophila)

chr14_-_87540920 8.647 NM_019670
Diap3
diaphanous homolog 3 (Drosophila)
chr11_-_40546863 8.563 NM_013552
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr14_+_68334187 8.459 Kctd9
potassium channel tetramerisation domain containing 9
chr14_-_48037815 8.431 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr5_-_138613028 8.330 NM_008568
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr14_-_87540995 8.282 Diap3
diaphanous homolog 3 (Drosophila)
chr17_+_46633703 8.227 NM_207161
BC048355
cDNA sequence BC048355
chr18_-_34911152 8.191 NM_009860
Cdc25c
cell division cycle 25 homolog C (S. pombe)
chr7_-_59117613 8.147 NM_001115087
Fancf
Fanconi anemia, complementation group F
chr14_+_68334154 8.143 NM_001111028
NM_134073
Kctd9

potassium channel tetramerisation domain containing 9

chr1_-_191511950 8.117 NM_001081363
Cenpf
centromere protein F
chr9_-_61794540 8.083 NM_024245
Kif23
kinesin family member 23
chr11_-_61307598 8.012 NM_011841
Mapk7
mitogen-activated protein kinase 7
chr8_-_13890244 7.982 NM_025556
2410022L05Rik
RIKEN cDNA 2410022L05 gene
chr4_+_108252056 7.969 NM_011015
Orc1
origin recognition complex, subunit 1
chr10_+_7387285 7.907 NM_145706
Nup43
nucleoporin 43
chr11_-_86014640 7.907 NM_178309
Brip1
BRCA1 interacting protein C-terminal helicase 1
chr18_-_33373428 7.876 NM_133774
Stard4
StAR-related lipid transfer (START) domain containing 4
chr6_-_8209105 7.821 Rpa3
replication protein A3
chr5_+_91320265 7.805 NM_008176
Cxcl1
chemokine (C-X-C motif) ligand 1
chr13_-_23854226 7.803 NM_013550
Hist1h3a
histone cluster 1, H3a
chr14_-_48037874 7.782 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr6_+_85401450 7.766 NM_007638
Cct7
chaperonin containing Tcp1, subunit 7 (eta)
chr2_+_118639930 7.735 D2Ertd750e
DNA segment, Chr 2, ERATO Doi 750, expressed
chr17_+_71554015 7.626 Lpin2
lipin 2
chr13_-_12350266 7.567 NM_001081128
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr1_-_193399412 7.560 NM_029766
Dtl
denticleless homolog (Drosophila)
chr13_+_23646900 7.476 NM_145713
Hist1h1d
histone cluster 1, H1d
chr15_+_98905403 7.398 NM_001162506
NM_030159
Troap

trophinin associated protein

chr19_-_8893759 7.388 NM_027412
Ttc9c
tetratricopeptide repeat domain 9C
chr4_+_98590565 7.357 Usp1
ubiquitin specific peptidase 1
chr4_+_130037378 7.330 NM_025645
Snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr6_-_8209135 7.294 NM_026632
Rpa3
replication protein A3
chr15_+_85690375 7.212 NM_013882
Gtse1
G two S phase expressed protein 1
chr6_+_128312987 7.185 NM_008021
Foxm1
forkhead box M1
chr6_+_145564482 7.184 NM_009449
Tuba3b
tubulin, alpha 3B
chr11_-_61307721 7.087 Mapk7
mitogen-activated protein kinase 7
chr6_-_125236045 7.073 NM_009446
Tuba3a
tubulin, alpha 3A
chr6_+_128313041 7.032 Foxm1
forkhead box M1
chr4_-_91042997 6.913 NM_001177883
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chrX_-_137491205 6.881 NM_001164177
NM_016883
Psmd10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr13_+_49777464 6.849 NM_172015
Iars
isoleucine-tRNA synthetase
chr13_-_21872421 6.828 NM_020034
Hist1h1b
histone cluster 1, H1b
chr4_-_132066370 6.819 NM_144907
Sesn2
sestrin 2
chr13_+_23666249 6.729 NM_178188
Hist1h2ad
Hist1h2ai
histone cluster 1, H2ad
histone cluster 1, H2ai
chr17_-_71196116 6.687 NM_001164077
Tgif1
TGFB-induced factor homeobox 1
chr2_+_72314235 6.646 NM_025866
Cdca7
cell division cycle associated 7
chr7_-_27963760 6.616 NM_029391
Rab4b
RAB4B, member RAS oncogene family
chr17_+_71553920 6.575 NM_001164885
Lpin2
lipin 2
chr6_-_145024487 6.568 Bcat1
branched chain aminotransferase 1, cytosolic
chr11_+_105043195 6.565 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr16_-_48994193 6.552 Dzip3
DAZ interacting protein 3, zinc finger
chr3_-_75360749 6.533 Pdcd10
programmed cell death 10
chr1_+_133424544 6.516 NM_175382
Fam72a
family with sequence similarity 72, member A
chr4_+_11486066 6.447 NM_001039556
Rad54b
RAD54 homolog B (S. cerevisiae)
chr15_+_81846798 6.444 NM_010247
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr4_-_129318200 6.422 Txlna
taxilin alpha
chr10_-_88906629 6.407 NM_001033331
NM_001079876
Gas2l3

growth arrest-specific 2 like 3

chr15_+_85690136 6.403 NM_001168672
Gtse1
G two S phase expressed protein 1
chr6_-_85401198 6.386 NM_001163427
NM_028505
1700040I03Rik

RIKEN cDNA 1700040I03 gene

chr10_+_75495391 6.369 Zfp280b
zinc finger protein 280B
chr2_+_119177025 6.369 Chac1
ChaC, cation transport regulator-like 1 (E. coli)
chr1_+_141351340 6.302 NM_009791
Aspm
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chrX_+_132804791 6.289 NM_001110233
NM_001110234
NM_009750
Ngfrap1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr12_+_101122706 6.269 NM_028354
Tdp1
tyrosyl-DNA phosphodiesterase 1
chr5_+_114580397 6.242 NM_001040691
Ung
uracil DNA glycosylase
chr3_-_100773571 6.138 NM_001013026
Ttf2
transcription termination factor, RNA polymerase II
chr19_-_8893358 6.137 Ttc9c
tetratricopeptide repeat domain 9C
chr13_-_34222209 6.136 NM_023716
Tubb2b
tubulin, beta 2B
chr6_-_145024451 6.083 Bcat1
branched chain aminotransferase 1, cytosolic
chr18_+_76401531 6.020 NM_010754
Smad2
MAD homolog 2 (Drosophila)
chrX_+_132804834 5.984 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr7_-_56136405 5.925 NM_001013368
E2f8
E2F transcription factor 8
chr6_-_13789847 5.914 NM_145066
Gpr85
G protein-coupled receptor 85
chr5_-_4104696 5.884 NM_020010
Cyp51
cytochrome P450, family 51
chr2_+_130100145 5.884 NM_024193
Nop56
NOP56 ribonucleoprotein homolog (yeast)
chr12_-_87165448 5.882 NM_021446
0610007P14Rik
RIKEN cDNA 0610007P14 gene
chr11_+_81859212 5.865 NM_013654
Ccl7
chemokine (C-C motif) ligand 7
chrX_+_132804865 5.857 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_-_18289209 5.841 NM_033324
Dgcr8
DiGeorge syndrome critical region gene 8
chr2_+_53050461 5.816 Arl6ip6
ADP-ribosylation factor-like 6 interacting protein 6
chr2_-_154395469 5.796 NM_007891
E2f1
E2F transcription factor 1
chr8_+_77633426 5.785 NM_008566
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.51 1.07e-17 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 2.68e-17 GO:0090304 nucleic acid metabolic process
1.38 3.69e-16 GO:0044260 cellular macromolecule metabolic process
2.06 4.82e-15 GO:0007049 cell cycle
1.43 1.85e-14 GO:0034641 cellular nitrogen compound metabolic process
1.41 2.13e-13 GO:0006807 nitrogen compound metabolic process
1.32 8.36e-13 GO:0043170 macromolecule metabolic process
2.17 1.36e-12 GO:0022402 cell cycle process
1.51 1.38e-11 GO:0016070 RNA metabolic process
2.28 1.13e-10 GO:0022403 cell cycle phase
2.44 1.72e-10 GO:0000279 M phase
1.46 2.31e-10 GO:0010467 gene expression
2.41 7.74e-10 GO:0051301 cell division
2.74 1.20e-09 GO:0000087 M phase of mitotic cell cycle
2.26 4.30e-09 GO:0000278 mitotic cell cycle
1.24 4.56e-09 GO:0044237 cellular metabolic process
1.44 9.19e-09 GO:0009059 macromolecule biosynthetic process
2.12 1.32e-08 GO:0051726 regulation of cell cycle
1.44 1.38e-08 GO:0034645 cellular macromolecule biosynthetic process
1.40 1.70e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 1.70e-08 GO:0051171 regulation of nitrogen compound metabolic process
2.66 1.73e-08 GO:0000280 nuclear division
2.66 1.73e-08 GO:0007067 mitosis
1.22 3.64e-08 GO:0044238 primary metabolic process
1.89 4.44e-08 GO:0033554 cellular response to stress
2.55 9.67e-08 GO:0048285 organelle fission
1.33 1.19e-07 GO:0060255 regulation of macromolecule metabolic process
2.12 2.73e-07 GO:0006974 response to DNA damage stimulus
1.34 4.92e-07 GO:0009058 biosynthetic process
1.98 5.22e-07 GO:0006259 DNA metabolic process
1.40 5.27e-07 GO:0051252 regulation of RNA metabolic process
1.41 5.44e-07 GO:0006355 regulation of transcription, DNA-dependent
1.38 7.60e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.60 1.03e-06 GO:0007399 nervous system development
1.31 1.33e-06 GO:0080090 regulation of primary metabolic process
1.37 1.54e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.32 1.68e-06 GO:0032502 developmental process
1.18 2.69e-06 GO:0008152 metabolic process
1.33 3.01e-06 GO:0044249 cellular biosynthetic process
1.36 3.13e-06 GO:0010468 regulation of gene expression
2.77 3.16e-06 GO:0006260 DNA replication
1.40 3.82e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.37 4.61e-06 GO:0048522 positive regulation of cellular process
1.33 4.92e-06 GO:0071840 cellular component organization or biogenesis
1.27 5.06e-06 GO:0019222 regulation of metabolic process
1.35 5.13e-06 GO:0048856 anatomical structure development
1.33 5.94e-06 GO:0007275 multicellular organismal development
1.44 1.08e-05 GO:0032774 RNA biosynthetic process
1.39 1.44e-05 GO:0071842 cellular component organization at cellular level
1.43 2.34e-05 GO:0006351 transcription, DNA-dependent
1.48 2.86e-05 GO:0006996 organelle organization
1.28 3.01e-05 GO:0031323 regulation of cellular metabolic process
1.32 4.68e-05 GO:0016043 cellular component organization
1.65 5.31e-05 GO:0022008 neurogenesis
1.34 8.94e-05 GO:0048731 system development
1.48 1.02e-04 GO:0009653 anatomical structure morphogenesis
1.38 1.12e-04 GO:0048869 cellular developmental process
1.31 1.20e-04 GO:0009889 regulation of biosynthetic process
1.31 1.41e-04 GO:0031326 regulation of cellular biosynthetic process
2.09 1.45e-04 GO:0033043 regulation of organelle organization
1.30 2.90e-04 GO:0048518 positive regulation of biological process
1.35 3.71e-04 GO:0048523 negative regulation of cellular process
2.05 4.56e-04 GO:0006281 DNA repair
1.36 7.90e-04 GO:0030154 cell differentiation
1.57 1.41e-03 GO:0051128 regulation of cellular component organization
2.17 1.51e-03 GO:0010564 regulation of cell cycle process
1.59 1.85e-03 GO:0048699 generation of neurons
1.30 2.77e-03 GO:0048519 negative regulation of biological process
2.24 3.53e-03 GO:0007346 regulation of mitotic cell cycle
1.49 4.21e-03 GO:0042981 regulation of apoptosis
1.48 4.65e-03 GO:0010941 regulation of cell death
1.52 5.34e-03 GO:2000026 regulation of multicellular organismal development
1.53 5.75e-03 GO:0010628 positive regulation of gene expression
1.48 7.91e-03 GO:0043067 regulation of programmed cell death
1.46 9.10e-03 GO:0050793 regulation of developmental process
2.62 1.02e-02 GO:0006310 DNA recombination
1.54 1.12e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.65 1.20e-02 GO:0006396 RNA processing
1.53 1.32e-02 GO:0051254 positive regulation of RNA metabolic process
2.25 1.49e-02 GO:0045786 negative regulation of cell cycle
1.65 1.52e-02 GO:0008284 positive regulation of cell proliferation
4.10 1.59e-02 GO:0030010 establishment of cell polarity
2.51 1.71e-02 GO:0010639 negative regulation of organelle organization
1.80 1.89e-02 GO:0016071 mRNA metabolic process
1.76 2.86e-02 GO:0051960 regulation of nervous system development
1.78 2.92e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.80 3.03e-02 GO:0050767 regulation of neurogenesis
1.38 3.43e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.63 3.60e-02 GO:0000075 cell cycle checkpoint
2.50 3.95e-02 GO:0007059 chromosome segregation
1.71 4.19e-02 GO:0060284 regulation of cell development
1.88 4.36e-02 GO:0008380 RNA splicing
1.49 4.98e-02 GO:0045595 regulation of cell differentiation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.48 4.42e-30 GO:0005634 nucleus
1.21 1.37e-21 GO:0044424 intracellular part
1.25 4.76e-21 GO:0043229 intracellular organelle
1.25 5.89e-21 GO:0043226 organelle
1.20 2.63e-20 GO:0005622 intracellular
1.26 2.34e-18 GO:0043231 intracellular membrane-bounded organelle
1.25 3.05e-18 GO:0043227 membrane-bounded organelle
1.66 2.44e-15 GO:0044428 nuclear part
1.73 7.50e-15 GO:0031981 nuclear lumen
1.60 9.16e-12 GO:0070013 intracellular organelle lumen
1.80 9.40e-12 GO:0005654 nucleoplasm
1.59 1.14e-11 GO:0043233 organelle lumen
1.57 6.38e-11 GO:0031974 membrane-enclosed lumen
2.15 3.73e-10 GO:0005694 chromosome
2.21 4.00e-10 GO:0044427 chromosomal part
1.30 6.10e-09 GO:0044446 intracellular organelle part
1.41 1.16e-08 GO:0043228 non-membrane-bounded organelle
1.41 1.16e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.28 6.02e-08 GO:0044422 organelle part
1.32 1.17e-07 GO:0032991 macromolecular complex
1.17 3.71e-07 GO:0005737 cytoplasm
1.34 7.23e-07 GO:0043234 protein complex
1.69 1.70e-05 GO:0044451 nucleoplasm part
1.45 2.03e-05 GO:0005829 cytosol
3.14 3.04e-05 GO:0000776 kinetochore
2.16 4.04e-04 GO:0000228 nuclear chromosome
2.18 1.29e-03 GO:0044454 nuclear chromosome part
2.39 1.49e-03 GO:0000775 chromosome, centromeric region
3.33 4.35e-03 GO:0030496 midbody
1.98 8.48e-03 GO:0000785 chromatin
2.39 8.52e-03 GO:0005819 spindle
1.70 1.19e-02 GO:0005730 nucleolus
3.18 1.48e-02 GO:0016363 nuclear matrix
1.41 2.37e-02 GO:0044430 cytoskeletal part
2.39 2.52e-02 GO:0000793 condensed chromosome
1.31 3.35e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.51 3.89e-14 GO:0003676 nucleic acid binding
1.15 1.16e-10 GO:0005488 binding
1.53 1.32e-09 GO:0003677 DNA binding
1.22 1.16e-06 GO:0005515 protein binding
1.44 5.74e-05 GO:0005524 ATP binding
1.43 8.50e-05 GO:0032559 adenyl ribonucleotide binding
1.42 1.22e-04 GO:0030554 adenyl nucleotide binding
1.34 1.43e-04 GO:0000166 nucleotide binding
2.20 3.72e-04 GO:0003682 chromatin binding
1.35 8.71e-04 GO:0032555 purine ribonucleotide binding
1.35 9.09e-04 GO:0032553 ribonucleotide binding
1.34 1.17e-03 GO:0017076 purine nucleotide binding
1.35 1.41e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.48 3.04e-03 GO:0030528 transcription regulator activity
1.53 6.59e-03 GO:0003723 RNA binding
3.47 1.47e-02 GO:0008094 DNA-dependent ATPase activity
1.48 2.09e-02 GO:0001071 nucleic acid binding transcription factor activity
1.48 2.09e-02 GO:0003700 sequence-specific DNA binding transcription factor activity