Motif ID: GTF2I.p2

Z-value: 2.007


Transcription factors associated with GTF2I.p2:

Gene SymbolEntrez IDGene Name
Gtf2i 14886 general transcription factor II I

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gtf2ichr5_-_1347902770.381.1e-07Click!


Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_37182910 34.757 NM_019439
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_-_42340613 34.722 NM_008083
Gap43
growth associated protein 43
chr1_-_82287990 31.340 NM_010570
Irs1
insulin receptor substrate 1
chr5_+_37637027 29.234 NM_007765
Crmp1
collapsin response mediator protein 1
chrX_+_70728994 28.213 Bgn
biglycan
chr4_+_126290825 27.888


chr6_-_77929543 27.478 Ctnna2
catenin (cadherin associated protein), alpha 2
chr7_-_25772525 26.870 Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr6_-_77929685 25.176 Ctnna2
catenin (cadherin associated protein), alpha 2
chrX_+_70728939 24.294 NM_007542
Bgn
biglycan
chr14_-_55735114 23.098 NM_177049
Jph4
junctophilin 4
chr11_+_69831951 22.612 NM_001109752
NM_007864
Dlg4

discs, large homolog 4 (Drosophila)

chr4_+_138011061 22.538 NM_025451
Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr9_+_43851466 22.400 NM_009382
Thy1
thymus cell antigen 1, theta
chr6_-_77929660 22.342 NM_001109764
NM_009819
NM_145732
Ctnna2


catenin (cadherin associated protein), alpha 2


chr2_-_181048957 22.332 Stmn3
stathmin-like 3
chr2_+_136539202 21.744 Snap25
synaptosomal-associated protein 25
chr13_+_42804911 21.629 NM_001005740
Phactr1
phosphatase and actin regulator 1
chr2_+_136539143 21.337 NM_011428
Snap25
synaptosomal-associated protein 25
chrX_+_162782484 20.974 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chr7_-_25857275 20.738 NM_008168
Grik5
glutamate receptor, ionotropic, kainate 5 (gamma 2)
chr1_+_66515003 19.622 NM_175510
Unc80
unc-80 homolog (C. elegans)
chr11_+_69832336 19.268 Dlg4
discs, large homolog 4 (Drosophila)
chr9_-_86775282 19.214 Snap91
synaptosomal-associated protein 91
chr8_-_105308910 18.897 NM_009866
Cdh11
cadherin 11
chrX_-_73119876 18.713 Pls3
plastin 3 (T-isoform)
chr2_-_181049204 18.396 NM_009133
Stmn3
stathmin-like 3
chr3_+_55046548 17.947 Dclk1
doublecortin-like kinase 1
chr7_+_134094045 17.870 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr7_+_52955153 17.556 NM_009800
Car11
carbonic anhydrase 11
chr1_+_160292665 17.423 Astn1
astrotactin 1
chr6_+_4455686 17.244 NM_007743
Col1a2
collagen, type I, alpha 2
chr7_+_64846528 16.920 NM_008071
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr7_-_17200285 16.772 NM_172739
Grlf1
glucocorticoid receptor DNA binding factor 1
chr12_-_87419813 16.601 NM_009368
Tgfb3
transforming growth factor, beta 3
chr8_+_96334879 16.583 Gnao1
guanine nucleotide binding protein, alpha O
chr18_-_16967557 15.914 NM_007664
Cdh2
cadherin 2
chrX_-_133403050 15.534 NM_176971
Rab9b
RAB9B, member RAS oncogene family
chrX_-_132749976 15.489 NM_009052
Bex1
brain expressed gene 1
chr10_+_13685882 15.464 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_+_133966816 15.032 NM_029978
Fam57b
family with sequence similarity 57, member B
chr1_-_166387998 14.996 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr13_-_100286446 14.907 Mtap1b
microtubule-associated protein 1B
chr7_+_64846558 14.732 Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr9_-_58884114 14.725 NM_001042752
NM_008684
Neo1

neogenin

chr9_+_40494076 14.711 9030425E11Rik
RIKEN cDNA 9030425E11 gene
chr13_-_78338131 14.644 NM_010151
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr15_+_98462650 14.543 NM_001044741
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr14_-_30534966 14.478 NM_009785
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr6_-_77929575 14.425 Ctnna2
catenin (cadherin associated protein), alpha 2
chr4_+_126291095 14.366 5730409E04Rik
RIKEN cDNA 5730409E04Rik gene
chr2_-_115890747 14.302 NM_001136072
NM_001159567
NM_001159568
NM_010825
Meis2



Meis homeobox 2



chrX_+_132373572 14.268 NM_001163015
NM_001163016
NM_001163017
Gprasp2


G protein-coupled receptor associated sorting protein 2


chr15_+_32850477 14.173 NM_008304
Sdc2
syndecan 2
chr9_+_27598853 13.979 NM_177906
Opcml
opioid binding protein/cell adhesion molecule-like
chr4_-_82151590 13.921 Nfib
nuclear factor I/B
chr11_-_55233354 13.823 Sparc
secreted acidic cysteine rich glycoprotein
chr17_+_87506971 13.730 NM_019654
Socs5
suppressor of cytokine signaling 5
chr3_+_156224757 13.716 NM_001039094
NM_177274
Negr1

neuronal growth regulator 1

chr5_-_133018212 13.509 NM_177047
Auts2
autism susceptibility candidate 2
chr9_-_91260619 13.361 NM_009573
Zic1
zinc finger protein of the cerebellum 1
chr18_-_16967754 13.281 Cdh2
cadherin 2
chr18_-_33623069 13.133 NM_001109990
D0H4S114
DNA segment, human D4S114
chr14_-_55531726 12.854 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr13_-_100286521 12.830 NM_008634
Mtap1b
microtubule-associated protein 1B
chr7_-_52622373 12.817 NM_029741
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr16_-_20621287 12.693 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr2_-_52532100 12.631 NM_001037099
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr8_-_87298118 12.607 NM_001081981
Nfix
nuclear factor I/X
chr9_+_40493989 12.407 NM_133733
9030425E11Rik
RIKEN cDNA 9030425E11 gene
chr4_+_149022081 12.165 Clstn1
calsyntenin 1
chr2_+_25258653 12.146 Npdc1
neural proliferation, differentiation and control gene 1
chr10_-_76188683 12.113 NM_009933
Col6a1
collagen, type VI, alpha 1
chrX_-_73119905 11.980 NM_145629
Pls3
plastin 3 (T-isoform)
chr18_-_33623400 11.882 NM_001109989
D0H4S114
DNA segment, human D4S114
chr12_-_73509668 11.873 Rtn1
reticulon 1
chr7_-_52622289 11.867 Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr15_-_91403685 11.694 NM_001033633
Slc2a13
solute carrier family 2 (facilitated glucose transporter), member 13
chr4_+_13670582 11.635 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_124807704 11.586 NM_013534
Leprel2
leprecan-like 2
chr17_+_25945986 11.577 NM_001164225
Fbxl16
F-box and leucine-rich repeat protein 16
chr11_-_83880574 11.574 Dusp14
dual specificity phosphatase 14
chr4_+_54960816 11.407 NM_172867
Zfp462
zinc finger protein 462
chr3_+_113733457 11.359 NM_007729
Col11a1
collagen, type XI, alpha 1
chr1_+_160292470 11.342 NM_007495
Astn1
astrotactin 1
chr6_-_36759929 11.326 Ptn
pleiotrophin
chr18_-_33623287 11.306 NM_053078
D0H4S114
DNA segment, human D4S114
chr11_-_61267383 11.256 NM_009548
Rnf112
ring finger protein 112
chr2_+_31951030 11.222 Ppapdc3
phosphatidic acid phosphatase type 2 domain containing 3
chr7_-_52622167 11.213 Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr3_+_113733590 11.181 Col11a1
collagen, type XI, alpha 1
chr2_+_121184334 11.179 NM_009897
Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
chr3_+_55046447 11.095 NM_001111053
NM_001195538
NM_019978
Dclk1


doublecortin-like kinase 1


chr12_-_73509537 10.927 Rtn1
reticulon 1
chr10_-_80119815 10.912 NM_145361
Btbd2
BTB (POZ) domain containing 2
chr14_+_76814750 10.905 Tsc22d1
TSC22 domain family, member 1
chr1_+_154802091 10.893 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr2_-_180891448 10.888 Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr1_+_154802144 10.770 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr4_-_82151004 10.591 Nfib
nuclear factor I/B
chr6_+_29346606 10.575 NM_145574
Ccdc136
coiled-coil domain containing 136
chr6_+_114232618 10.548 NM_178703
Slc6a1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr10_+_4424140 10.505 NM_001161822
NM_019958
Rgs17

regulator of G-protein signaling 17

chr13_-_36826245 10.494 NM_153529
Nrn1
neuritin 1
chr10_-_108447674 10.450 NM_009306
Syt1
synaptotagmin I
chr15_-_77136972 10.422 Rbfox2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_56387565 10.419 NM_010200
Fgf13
fibroblast growth factor 13
chr6_-_124807733 10.342 Leprel2
leprecan-like 2
chr8_+_65430028 10.328 NM_023689
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr9_-_86775154 10.266 NM_013669
Snap91
synaptosomal-associated protein 91
chr8_+_98226914 10.258 NM_001195006
NM_145602
Ndrg4

N-myc downstream regulated gene 4

chr2_+_169459145 10.255 NM_080455
Tshz2
teashirt zinc finger family member 2
chr10_+_4795808 10.222 NM_153399
Syne1
synaptic nuclear envelope 1
chr9_-_56483379 10.174 Lingo1
leucine rich repeat and Ig domain containing 1
chr4_+_115894518 10.171 NM_181585
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr11_-_55233581 10.168 NM_009242
Sparc
secreted acidic cysteine rich glycoprotein
chr7_+_4642529 10.161 NM_001003920
NM_001168572
Brsk1

BR serine/threonine kinase 1

chr6_-_124719465 10.158 NM_013509
Eno2
enolase 2, gamma neuronal
chr7_-_134164487 10.150 Prrt2
proline-rich transmembrane protein 2
chr14_-_94289847 10.133 Pcdh9
protocadherin 9
chr17_+_43938789 10.083 NM_207649
Rcan2
regulator of calcineurin 2
chr18_-_43552694 10.081 NM_009468
Dpysl3
dihydropyrimidinase-like 3
chr2_-_80421054 10.051 NM_016965
Nckap1
NCK-associated protein 1
chr6_-_126594802 9.988 Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr2_+_28048779 9.967 Olfm1
olfactomedin 1
chr19_-_44482138 9.966 NM_009127
Scd1
stearoyl-Coenzyme A desaturase 1
chr19_+_8738494 9.955 NM_001112697
NM_007698
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr13_+_118391270 9.914 Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr18_-_25912453 9.708 NM_001146292
NM_001146293
NM_001146294
NM_001146295
NM_001174074
NM_133195
Celf4





CUGBP, Elav-like family member 4





chr5_-_9725274 9.657 NM_181850
Grm3
glutamate receptor, metabotropic 3
chr11_-_118770873 9.644 NM_001024931
NM_001039167
NM_001039168
Rbfox3


RNA binding protein, fox-1 homolog (C. elegans) 3


chr5_+_37633353 9.630 Crmp1
collapsin response mediator protein 1
chr17_+_37187550 9.499 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_116515361 9.440 Cygb
cytoglobin
chr15_-_98638348 9.428 NM_001013741
Ddn
dendrin
chr18_-_75857207 9.403 NM_201354
Ctif
CBP80/20-dependent translation initiation factor
chr11_-_55233366 9.353 Sparc
secreted acidic cysteine rich glycoprotein
chr13_+_54472806 9.339 Cplx2
complexin 2
chr4_+_137283714 9.338 Rap1gap
Rap1 GTPase-activating protein
chr1_+_154802198 9.322 NM_175460
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr7_+_52955569 9.320 Car11
carbonic anhydrase 11
chr5_-_45190857 9.315 NM_001077398
NM_010698
Ldb2

LIM domain binding 2

chr15_-_76983985 9.147 NM_001110828
NM_001110829
NM_001110830
Rbfox2


RNA binding protein, fox-1 homolog (C. elegans) 2


chr2_-_130468507 9.134 NM_197945
Prosapip1
ProSAPiP1 protein
chr9_+_40494347 9.076 9030425E11Rik
RIKEN cDNA 9030425E11 gene
chr15_+_91881593 9.061 NM_001159648
Cntn1
contactin 1
chr15_-_98638230 9.025 Ddn
dendrin
chr10_-_108448003 8.949 Syt1
synaptotagmin I
chr2_+_164793487 8.945 NM_020333
Slc12a5
solute carrier family 12, member 5
chr15_-_102347249 8.933 Map3k12
mitogen-activated protein kinase kinase kinase 12
chr6_-_113841295 8.865 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr7_+_80536079 8.846 Rgma
RGM domain family, member A
chr19_+_27291897 8.820 Vldlr
very low density lipoprotein receptor
chr7_+_119571219 8.796 NM_020606
Parva
parvin, alpha
chr11_-_118770859 8.775 Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr7_-_31699850 8.772 NM_010758
Mag
myelin-associated glycoprotein
chr13_+_46597271 8.742 NM_026056
Cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr7_-_31840647 8.613 NM_019503
NM_052992
Fxyd1

FXYD domain-containing ion transport regulator 1

chr7_-_52230091 8.575 Cpt1c
carnitine palmitoyltransferase 1c
chr2_-_64860728 8.552 NM_016719
Grb14
growth factor receptor bound protein 14
chr11_-_69648350 8.522 NM_198862
Nlgn2
neuroligin 2
chr16_+_6349108 8.512 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr19_+_8738840 8.498 Chrm1
cholinergic receptor, muscarinic 1, CNS
chr12_-_5382487 8.462 NM_001164493
Klhl29
kelch-like 29 (Drosophila)
chr7_-_134164627 8.443 NM_001102563
Prrt2
proline-rich transmembrane protein 2
chr7_-_52230117 8.389 NM_153679
Cpt1c
carnitine palmitoyltransferase 1c
chr13_-_55589463 8.374 Dbn1
drebrin 1
chr16_+_35154935 8.344 Adcy5
adenylate cyclase 5
chr5_+_143734622 8.276


chr7_-_31911754 8.273 Scn1b
sodium channel, voltage-gated, type I, beta
chr14_+_67530044 8.256 NM_175498
Pnma2
paraneoplastic antigen MA2
chr14_-_68743060 8.218 NM_008691
Nefm
neurofilament, medium polypeptide
chr13_-_36826104 8.207 Nrn1
neuritin 1
chr1_-_25886551 8.201 NM_175642
Bai3
brain-specific angiogenesis inhibitor 3
chr9_+_68501551 8.198 NM_013646
Rora
RAR-related orphan receptor alpha
chr11_-_11937330 8.181 NM_010345
Grb10
growth factor receptor bound protein 10
chr3_+_90346956 8.176 S100a16
S100 calcium binding protein A16
chr19_-_44482033 8.166 Scd1
stearoyl-Coenzyme A desaturase 1
chr2_+_177876858 8.154 Phactr3
phosphatase and actin regulator 3
chr2_+_32484995 8.152 NM_021515
Ak1
adenylate kinase 1
chr7_-_31840594 8.146 Fxyd1
FXYD domain-containing ion transport regulator 1
chr2_+_164793698 8.102 Slc12a5
solute carrier family 12, member 5
chr9_+_104472090 8.096 NM_028719
Cpne4
copine IV
chr6_-_124867962 8.077 NM_026988
Ptms
parathymosin
chr14_+_56129440 8.020 Cpne6
copine VI
chr18_+_57292743 8.005 NM_001001979
Megf10
multiple EGF-like-domains 10
chrX_-_69901382 7.988 NM_008067
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr8_-_87296172 7.957 Nfix
nuclear factor I/X
chr2_+_48805027 7.908 NM_029924
Mbd5
methyl-CpG binding domain protein 5
chr7_-_112781902 7.895 NM_018880
Trim3
tripartite motif-containing 3
chr7_-_52230179 7.891 Cpt1c
carnitine palmitoyltransferase 1c
chr6_-_113841356 7.861 NM_001036684
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr7_+_103359146 7.850 NM_011858
Odz4
odd Oz/ten-m homolog 4 (Drosophila)
chr9_-_21856445 7.761 NM_010487
Elavl3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr6_-_124867872 7.714 Ptms
parathymosin
chr2_-_58368568 7.702 Acvr1
activin A receptor, type 1
chr4_-_126427788 7.697 Ncdn
neurochondrin
chr7_-_31147752 7.675 NM_175478
Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
chr5_+_37259906 7.669 Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr18_-_25912171 7.636 Celf4
CUGBP, Elav-like family member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.82 1.42e-37 GO:0007399 nervous system development
1.53 9.70e-36 GO:0048731 system development
1.47 2.01e-32 GO:0048856 anatomical structure development
1.95 7.32e-32 GO:0048699 generation of neurons
1.44 1.28e-31 GO:0007275 multicellular organismal development
1.90 2.18e-30 GO:0022008 neurogenesis
1.40 1.19e-29 GO:0032502 developmental process
1.64 1.23e-26 GO:0009653 anatomical structure morphogenesis
2.00 9.00e-24 GO:0030182 neuron differentiation
2.13 1.58e-23 GO:0048666 neuron development
1.58 2.03e-23 GO:0023051 regulation of signaling
1.36 4.79e-23 GO:0051179 localization
1.76 1.23e-22 GO:0048468 cell development
1.45 3.33e-22 GO:0048523 negative regulation of cellular process
1.42 6.93e-22 GO:0048519 negative regulation of biological process
1.55 8.80e-22 GO:0051239 regulation of multicellular organismal process
2.24 1.31e-21 GO:0031175 neuron projection development
1.37 5.14e-21 GO:0048518 positive regulation of biological process
1.45 8.25e-21 GO:0048869 cellular developmental process
1.46 1.50e-20 GO:0030154 cell differentiation
1.97 2.21e-20 GO:0030030 cell projection organization
1.29 2.41e-20 GO:0019222 regulation of metabolic process
1.39 8.30e-20 GO:0048522 positive regulation of cellular process
1.31 5.31e-19 GO:0031323 regulation of cellular metabolic process
1.99 1.60e-18 GO:0000902 cell morphogenesis
1.30 5.42e-18 GO:0080090 regulation of primary metabolic process
2.29 8.09e-18 GO:0048812 neuron projection morphogenesis
1.60 1.24e-17 GO:0010646 regulation of cell communication
1.34 1.36e-17 GO:0016043 cellular component organization
1.91 3.28e-17 GO:0032989 cellular component morphogenesis
2.14 3.33e-17 GO:0000904 cell morphogenesis involved in differentiation
1.55 3.66e-17 GO:0009966 regulation of signal transduction
1.60 4.91e-17 GO:0050793 regulation of developmental process
1.35 6.66e-17 GO:0006810 transport
1.34 6.69e-17 GO:0051234 establishment of localization
1.32 6.96e-17 GO:0071840 cellular component organization or biogenesis
2.13 7.27e-17 GO:0048858 cell projection morphogenesis
2.10 1.99e-16 GO:0032990 cell part morphogenesis
1.75 3.68e-16 GO:0007154 cell communication
1.94 1.75e-15 GO:0060284 regulation of cell development
2.27 7.51e-15 GO:0007409 axonogenesis
1.65 1.32e-14 GO:0045595 regulation of cell differentiation
1.61 1.43e-14 GO:2000026 regulation of multicellular organismal development
2.19 2.12e-14 GO:0048667 cell morphogenesis involved in neuron differentiation
1.44 1.03e-13 GO:0065009 regulation of molecular function
1.92 1.63e-13 GO:0051960 regulation of nervous system development
1.42 1.79e-13 GO:0048583 regulation of response to stimulus
1.39 1.80e-13 GO:0065008 regulation of biological quality
1.97 3.05e-13 GO:0050767 regulation of neurogenesis
1.39 3.50e-13 GO:0048513 organ development
2.07 3.63e-13 GO:0045664 regulation of neuron differentiation
1.86 4.83e-13 GO:0007267 cell-cell signaling
1.35 1.28e-12 GO:0071842 cellular component organization at cellular level
1.51 2.64e-12 GO:0032879 regulation of localization
1.33 3.91e-12 GO:0071841 cellular component organization or biogenesis at cellular level
1.26 5.15e-12 GO:0060255 regulation of macromolecule metabolic process
1.57 5.36e-12 GO:0051128 regulation of cellular component organization
1.60 8.56e-12 GO:0051049 regulation of transport
1.28 2.66e-11 GO:0051171 regulation of nitrogen compound metabolic process
1.89 3.50e-11 GO:0019226 transmission of nerve impulse
1.89 3.50e-11 GO:0035637 multicellular organismal signaling
1.28 1.60e-10 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.79 1.70e-10 GO:0044057 regulation of system process
1.84 3.43e-10 GO:0022603 regulation of anatomical structure morphogenesis
1.44 3.59e-10 GO:0050790 regulation of catalytic activity
1.60 1.29e-09 GO:0009887 organ morphogenesis
1.95 1.36e-09 GO:0007268 synaptic transmission
1.80 1.76e-09 GO:0007167 enzyme linked receptor protein signaling pathway
1.83 2.18e-09 GO:0035295 tube development
1.12 3.21e-09 GO:0065007 biological regulation
1.45 3.70e-09 GO:0051641 cellular localization
1.59 3.97e-09 GO:0007155 cell adhesion
1.48 6.79e-09 GO:0009888 tissue development
1.25 7.47e-09 GO:0009889 regulation of biosynthetic process
1.58 9.51e-09 GO:0022610 biological adhesion
1.69 1.37e-08 GO:0007417 central nervous system development
1.08 1.74e-08 GO:0009987 cellular process
1.78 2.00e-08 GO:0007420 brain development
1.15 2.13e-08 GO:0044237 cellular metabolic process
1.63 2.37e-08 GO:0072358 cardiovascular system development
1.63 2.37e-08 GO:0072359 circulatory system development
1.25 2.42e-08 GO:0031326 regulation of cellular biosynthetic process
2.11 3.19e-08 GO:0010975 regulation of neuron projection development
1.12 4.48e-08 GO:0050789 regulation of biological process
1.43 1.12e-07 GO:0031324 negative regulation of cellular metabolic process
1.41 1.20e-07 GO:0009892 negative regulation of metabolic process
2.06 1.26e-07 GO:0043062 extracellular structure organization
1.70 1.81e-07 GO:0051093 negative regulation of developmental process
1.98 1.83e-07 GO:0031344 regulation of cell projection organization
1.14 1.84e-07 GO:0044238 primary metabolic process
1.41 1.99e-07 GO:0051246 regulation of protein metabolic process
1.41 2.01e-07 GO:0035556 intracellular signal transduction
1.99 2.20e-07 GO:0050804 regulation of synaptic transmission
2.15 3.38e-07 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.15 3.38e-07 GO:0022604 regulation of cell morphogenesis
1.52 3.66e-07 GO:0019220 regulation of phosphate metabolic process
1.52 3.66e-07 GO:0051174 regulation of phosphorus metabolic process
1.94 3.70e-07 GO:0051969 regulation of transmission of nerve impulse
1.12 4.93e-07 GO:0050794 regulation of cellular process
1.89 5.13e-07 GO:0031644 regulation of neurological system process
1.76 5.15e-07 GO:0045596 negative regulation of cell differentiation
1.24 6.46e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.23 1.20e-06 GO:0010468 regulation of gene expression
1.41 1.58e-06 GO:0032268 regulation of cellular protein metabolic process
1.78 1.61e-06 GO:0006140 regulation of nucleotide metabolic process
1.43 1.90e-06 GO:0051649 establishment of localization in cell
1.23 2.20e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.50 2.23e-06 GO:0042325 regulation of phosphorylation
1.66 2.51e-06 GO:0048729 tissue morphogenesis
1.44 3.17e-06 GO:0009790 embryo development
2.08 3.18e-06 GO:0030811 regulation of nucleotide catabolic process
2.08 3.18e-06 GO:0033121 regulation of purine nucleotide catabolic process
1.55 3.25e-06 GO:0010647 positive regulation of cell communication
1.71 3.31e-06 GO:0001944 vasculature development
1.77 3.70e-06 GO:0001501 skeletal system development
1.11 3.91e-06 GO:0008152 metabolic process
1.16 4.00e-06 GO:0044260 cellular macromolecule metabolic process
1.86 4.51e-06 GO:0030900 forebrain development
1.54 5.27e-06 GO:0023056 positive regulation of signaling
1.60 5.35e-06 GO:0060341 regulation of cellular localization
1.38 9.05e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.97 9.50e-06 GO:0016055 Wnt receptor signaling pathway
1.44 9.99e-06 GO:0009890 negative regulation of biosynthetic process
2.13 1.00e-05 GO:0030324 lung development
1.53 1.14e-05 GO:0019725 cellular homeostasis
2.04 1.41e-05 GO:0060541 respiratory system development
1.49 1.47e-05 GO:0040011 locomotion
1.55 1.53e-05 GO:0009967 positive regulation of signal transduction
1.49 1.53e-05 GO:0016192 vesicle-mediated transport
1.23 1.75e-05 GO:0006355 regulation of transcription, DNA-dependent
1.23 1.80e-05 GO:0051252 regulation of RNA metabolic process
2.09 2.03e-05 GO:0030323 respiratory tube development
1.42 2.12e-05 GO:0006811 ion transport
1.80 2.36e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.53 2.41e-05 GO:0009792 embryo development ending in birth or egg hatching
1.62 2.53e-05 GO:0016477 cell migration
1.80 2.67e-05 GO:0051129 negative regulation of cellular component organization
1.53 2.69e-05 GO:0043009 chordate embryonic development
1.43 2.78e-05 GO:0031399 regulation of protein modification process
1.30 2.82e-05 GO:0009893 positive regulation of metabolic process
1.72 3.72e-05 GO:0031329 regulation of cellular catabolic process
1.36 3.74e-05 GO:0008104 protein localization
1.31 3.77e-05 GO:0031325 positive regulation of cellular metabolic process
1.66 3.79e-05 GO:0009894 regulation of catabolic process
1.42 4.06e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.60 4.38e-05 GO:0007610 behavior
1.36 4.52e-05 GO:0010941 regulation of cell death
1.55 5.66e-05 GO:0055082 cellular chemical homeostasis
1.31 6.84e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.95 7.53e-05 GO:0048705 skeletal system morphogenesis
1.14 7.55e-05 GO:0043170 macromolecule metabolic process
1.61 1.02e-04 GO:0007423 sensory organ development
1.55 1.14e-04 GO:0048598 embryonic morphogenesis
1.32 1.16e-04 GO:0033036 macromolecule localization
1.55 1.40e-04 GO:0023057 negative regulation of signaling
1.37 1.47e-04 GO:0042127 regulation of cell proliferation
1.55 1.65e-04 GO:0010648 negative regulation of cell communication
2.02 1.74e-04 GO:0033124 regulation of GTP catabolic process
1.84 1.82e-04 GO:0034762 regulation of transmembrane transport
1.42 1.85e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
2.11 1.95e-04 GO:0003001 generation of a signal involved in cell-cell signaling
2.11 1.95e-04 GO:0023061 signal release
1.67 1.99e-04 GO:0002009 morphogenesis of an epithelium
1.53 2.10e-04 GO:0006873 cellular ion homeostasis
1.26 2.15e-04 GO:0006464 protein modification process
1.42 2.37e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.49 2.48e-04 GO:0030001 metal ion transport
1.90 2.62e-04 GO:0050678 regulation of epithelial cell proliferation
1.46 2.94e-04 GO:0001932 regulation of protein phosphorylation
1.40 3.34e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.39 3.47e-04 GO:0044093 positive regulation of molecular function
2.00 3.56e-04 GO:0043087 regulation of GTPase activity
1.57 3.82e-04 GO:0008285 negative regulation of cell proliferation
2.01 3.89e-04 GO:0007411 axon guidance
1.53 4.29e-04 GO:0061024 membrane organization
1.35 5.10e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.63 5.21e-04 GO:0001568 blood vessel development
1.51 5.34e-04 GO:0006928 cellular component movement
1.52 5.72e-04 GO:0016044 cellular membrane organization
1.40 6.35e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.01 6.36e-04 GO:0032386 regulation of intracellular transport
1.52 6.68e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.52 7.62e-04 GO:0048870 cell motility
1.52 7.62e-04 GO:0051674 localization of cell
1.46 7.91e-04 GO:0048646 anatomical structure formation involved in morphogenesis
2.16 8.57e-04 GO:0006836 neurotransmitter transport
1.33 8.57e-04 GO:0043067 regulation of programmed cell death
2.07 9.50e-04 GO:0031346 positive regulation of cell projection organization
1.54 9.60e-04 GO:0009968 negative regulation of signal transduction
1.92 9.67e-04 GO:0010720 positive regulation of cell development
1.69 1.02e-03 GO:0030029 actin filament-based process
1.45 1.04e-03 GO:0051094 positive regulation of developmental process
1.42 1.09e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.47 1.10e-03 GO:0051336 regulation of hydrolase activity
1.71 1.13e-03 GO:0030036 actin cytoskeleton organization
1.33 1.13e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.35 1.16e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 1.23e-03 GO:0016310 phosphorylation
1.49 1.30e-03 GO:0007010 cytoskeleton organization
1.32 1.48e-03 GO:0042981 regulation of apoptosis
1.32 1.81e-03 GO:0006796 phosphate metabolic process
1.79 1.89e-03 GO:0060562 epithelial tube morphogenesis
1.41 2.00e-03 GO:0051253 negative regulation of RNA metabolic process
1.95 2.16e-03 GO:0003012 muscle system process
1.55 2.17e-03 GO:0051130 positive regulation of cellular component organization
1.31 2.19e-03 GO:0006793 phosphorus metabolic process
2.21 2.27e-03 GO:0001764 neuron migration
1.68 2.29e-03 GO:0035239 tube morphogenesis
1.95 2.38e-03 GO:0030198 extracellular matrix organization
2.01 2.54e-03 GO:0006936 muscle contraction
2.01 2.54e-03 GO:0032318 regulation of Ras GTPase activity
2.01 2.54e-03 GO:0051216 cartilage development
1.38 2.63e-03 GO:0010629 negative regulation of gene expression
1.50 2.65e-03 GO:0032583 regulation of gene-specific transcription
1.23 2.90e-03 GO:0043412 macromolecule modification
1.38 2.90e-03 GO:0006468 protein phosphorylation
2.77 3.03e-03 GO:0051588 regulation of neurotransmitter transport
2.05 3.26e-03 GO:0048592 eye morphogenesis
2.20 3.48e-03 GO:0001505 regulation of neurotransmitter levels
1.95 3.53e-03 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.73 3.61e-03 GO:0043269 regulation of ion transport
1.35 3.70e-03 GO:0048584 positive regulation of response to stimulus
1.77 3.90e-03 GO:0042391 regulation of membrane potential
2.61 4.22e-03 GO:0007269 neurotransmitter secretion
1.97 4.30e-03 GO:0050769 positive regulation of neurogenesis
2.11 4.33e-03 GO:0050770 regulation of axonogenesis
1.45 6.21e-03 GO:0050801 ion homeostasis
2.01 6.23e-03 GO:0046822 regulation of nucleocytoplasmic transport
2.62 6.48e-03 GO:0048489 synaptic vesicle transport
1.30 6.57e-03 GO:0009891 positive regulation of biosynthetic process
1.39 6.70e-03 GO:0046907 intracellular transport
2.81 6.90e-03 GO:0046928 regulation of neurotransmitter secretion
1.38 7.14e-03 GO:0043085 positive regulation of catalytic activity
1.15 7.44e-03 GO:0034641 cellular nitrogen compound metabolic process
1.39 7.70e-03 GO:0006812 cation transport
2.49 7.89e-03 GO:0060349 bone morphogenesis
1.34 7.95e-03 GO:0045184 establishment of protein localization
2.44 8.36e-03 GO:0001649 osteoblast differentiation
1.30 8.63e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.40 8.89e-03 GO:0009605 response to external stimulus
1.47 9.46e-03 GO:0060429 epithelium development
1.34 9.57e-03 GO:0051254 positive regulation of RNA metabolic process
1.32 1.04e-02 GO:0022607 cellular component assembly
1.14 1.06e-02 GO:0006807 nitrogen compound metabolic process
1.33 1.15e-02 GO:0015031 protein transport
1.65 1.21e-02 GO:0001654 eye development
1.19 1.22e-02 GO:0044267 cellular protein metabolic process
1.47 1.23e-02 GO:0043549 regulation of kinase activity
1.31 1.26e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.49 1.28e-02 GO:0051050 positive regulation of transport
2.24 1.33e-02 GO:0050680 negative regulation of epithelial cell proliferation
1.32 1.43e-02 GO:0010628 positive regulation of gene expression
1.46 1.46e-02 GO:0051338 regulation of transferase activity
1.73 1.57e-02 GO:0051493 regulation of cytoskeleton organization
1.33 1.67e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.57 1.72e-02 GO:0043242 negative regulation of protein complex disassembly
1.96 1.73e-02 GO:0021953 central nervous system neuron differentiation
1.96 1.73e-02 GO:0033157 regulation of intracellular protein transport
1.46 1.84e-02 GO:0045597 positive regulation of cell differentiation
1.41 1.95e-02 GO:0048585 negative regulation of response to stimulus
1.43 1.96e-02 GO:0070727 cellular macromolecule localization
2.24 2.05e-02 GO:0070588 calcium ion transmembrane transport
2.39 2.07e-02 GO:0043244 regulation of protein complex disassembly
1.99 2.09e-02 GO:2000027 regulation of organ morphogenesis
1.93 2.10e-02 GO:0070482 response to oxygen levels
2.31 2.12e-02 GO:0050808 synapse organization
1.58 2.25e-02 GO:0061061 muscle structure development
1.90 2.25e-02 GO:0021537 telencephalon development
1.94 2.32e-02 GO:0001666 response to hypoxia
1.59 2.37e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.54 2.40e-02 GO:0048568 embryonic organ development
1.55 2.67e-02 GO:0007507 heart development
1.30 2.75e-02 GO:0042592 homeostatic process
1.82 2.78e-02 GO:0030111 regulation of Wnt receptor signaling pathway
1.36 2.90e-02 GO:0048878 chemical homeostasis
3.99 3.03e-02 GO:0021697 cerebellar cortex formation
1.76 3.08e-02 GO:0048589 developmental growth
1.78 3.14e-02 GO:0010959 regulation of metal ion transport
1.49 3.16e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.50 3.37e-02 GO:0046903 secretion
1.99 3.44e-02 GO:0010721 negative regulation of cell development
2.94 3.47e-02 GO:0030199 collagen fibril organization
1.42 3.67e-02 GO:0034613 cellular protein localization
1.60 3.72e-02 GO:0006897 endocytosis
1.60 3.72e-02 GO:0010324 membrane invagination
2.14 4.22e-02 GO:0051494 negative regulation of cytoskeleton organization
1.51 4.23e-02 GO:0001701 in utero embryonic development
1.70 4.46e-02 GO:0060537 muscle tissue development
1.49 4.61e-02 GO:0008283 cell proliferation
3.27 4.75e-02 GO:0021696 cerebellar cortex morphogenesis
2.05 4.86e-02 GO:0048167 regulation of synaptic plasticity

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.20 8.73e-49 GO:0005622 intracellular
1.20 1.31e-45 GO:0044424 intracellular part
1.26 1.91e-45 GO:0005737 cytoplasm
2.22 3.16e-39 GO:0043005 neuron projection
1.78 5.92e-33 GO:0042995 cell projection
1.18 7.38e-28 GO:0043226 organelle
2.11 7.58e-28 GO:0045202 synapse
1.18 9.73e-28 GO:0043229 intracellular organelle
1.34 9.02e-27 GO:0071944 cell periphery
1.09 1.83e-26 GO:0005623 cell
1.09 1.83e-26 GO:0044464 cell part
1.34 2.73e-25 GO:0005886 plasma membrane
1.24 6.92e-22 GO:0044444 cytoplasmic part
2.28 1.85e-21 GO:0030425 dendrite
2.17 3.92e-21 GO:0044456 synapse part
1.47 5.86e-21 GO:0044459 plasma membrane part
1.55 8.13e-18 GO:0000267 cell fraction
1.16 1.11e-17 GO:0043231 intracellular membrane-bounded organelle
1.77 1.51e-17 GO:0030054 cell junction
1.16 1.77e-17 GO:0043227 membrane-bounded organelle
2.05 1.96e-17 GO:0044297 cell body
2.08 2.04e-17 GO:0043025 neuronal cell body
2.19 9.64e-17 GO:0030424 axon
1.93 1.22e-16 GO:0044463 cell projection part
1.56 2.73e-14 GO:0005626 insoluble fraction
1.29 4.34e-13 GO:0043234 protein complex
1.54 1.76e-12 GO:0005624 membrane fraction
1.41 2.57e-12 GO:0005829 cytosol
1.48 1.44e-10 GO:0005794 Golgi apparatus
2.23 1.58e-10 GO:0045211 postsynaptic membrane
2.32 9.34e-10 GO:0033267 axon part
2.29 1.43e-09 GO:0019717 synaptosome
1.22 3.52e-09 GO:0032991 macromolecular complex
1.33 8.84e-08 GO:0005856 cytoskeleton
1.16 1.58e-07 GO:0005634 nucleus
1.98 4.15e-07 GO:0031252 cell leading edge
2.32 5.64e-07 GO:0008021 synaptic vesicle
3.11 1.29e-06 GO:0042734 presynaptic membrane
1.98 2.69e-06 GO:0030659 cytoplasmic vesicle membrane
1.42 3.50e-06 GO:0031982 vesicle
1.95 4.46e-06 GO:0044433 cytoplasmic vesicle part
2.00 5.27e-06 GO:0030136 clathrin-coated vesicle
1.91 5.83e-06 GO:0012506 vesicle membrane
1.61 1.03e-05 GO:0005625 soluble fraction
1.65 1.68e-05 GO:0048471 perinuclear region of cytoplasm
2.36 2.62e-05 GO:0044309 neuron spine
2.28 2.64e-05 GO:0030427 site of polarized growth
1.61 2.85e-05 GO:0031012 extracellular matrix
1.75 2.91e-05 GO:0016323 basolateral plasma membrane
1.87 3.56e-05 GO:0030135 coated vesicle
1.40 4.23e-05 GO:0031410 cytoplasmic vesicle
1.65 4.54e-05 GO:0015629 actin cytoskeleton
2.05 4.79e-05 GO:0044420 extracellular matrix part
2.57 7.15e-05 GO:0030665 clathrin coated vesicle membrane
2.90 7.79e-05 GO:0043198 dendritic shaft
1.37 8.36e-05 GO:0012505 endomembrane system
1.15 8.76e-05 GO:0044422 organelle part
1.15 9.32e-05 GO:0044446 intracellular organelle part
2.25 9.37e-05 GO:0030426 growth cone
2.29 1.48e-04 GO:0043197 dendritic spine
3.14 1.66e-04 GO:0030672 synaptic vesicle membrane
1.44 2.27e-04 GO:0031988 membrane-bounded vesicle
1.09 2.44e-04 GO:0016020 membrane
1.33 2.72e-04 GO:0044430 cytoskeletal part
1.60 3.20e-04 GO:0005578 proteinaceous extracellular matrix
2.01 5.48e-04 GO:0019898 extrinsic to membrane
1.89 6.55e-04 GO:0005912 adherens junction
2.13 6.61e-04 GO:0014069 postsynaptic density
1.75 7.86e-04 GO:0034702 ion channel complex
2.13 1.00e-03 GO:0005604 basement membrane
1.83 1.03e-03 GO:0070161 anchoring junction
1.42 1.03e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
2.63 1.43e-03 GO:0031594 neuromuscular junction
1.29 1.96e-03 GO:0044421 extracellular region part
1.54 2.72e-03 GO:0044431 Golgi apparatus part
1.27 2.93e-03 GO:0005783 endoplasmic reticulum
1.93 3.02e-03 GO:0034703 cation channel complex
2.03 3.93e-03 GO:0030027 lamellipodium
2.78 4.30e-03 GO:0044304 main axon
2.12 5.72e-03 GO:0030662 coated vesicle membrane
1.59 5.84e-03 GO:0005911 cell-cell junction
2.39 7.12e-03 GO:0005913 cell-cell adherens junction
2.39 7.12e-03 GO:0042641 actomyosin
1.99 8.12e-03 GO:0044306 neuron projection terminus
1.24 8.37e-03 GO:0031090 organelle membrane
2.02 9.71e-03 GO:0043679 axon terminus
2.39 1.10e-02 GO:0032432 actin filament bundle
1.53 1.54e-02 GO:0045177 apical part of cell
2.91 2.24e-02 GO:0043209 myelin sheath
1.15 3.61e-02 GO:0043228 non-membrane-bounded organelle
1.15 3.61e-02 GO:0043232 intracellular non-membrane-bounded organelle
2.33 4.16e-02 GO:0001725 stress fiber
1.97 4.49e-02 GO:0019897 extrinsic to plasma membrane
1.58 4.58e-02 GO:0016324 apical plasma membrane
3.02 4.97e-02 GO:0008328 ionotropic glutamate receptor complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.40 2.51e-63 GO:0005515 protein binding
1.21 3.05e-52 GO:0005488 binding
1.65 4.26e-17 GO:0019899 enzyme binding
1.72 1.18e-12 GO:0019904 protein domain specific binding
1.73 1.23e-12 GO:0008092 cytoskeletal protein binding
1.69 4.37e-11 GO:0005509 calcium ion binding
2.55 2.73e-10 GO:0019838 growth factor binding
1.21 1.18e-08 GO:0043169 cation binding
1.21 1.33e-08 GO:0046872 metal ion binding
1.47 1.82e-08 GO:0030234 enzyme regulator activity
1.21 2.71e-08 GO:0043167 ion binding
1.68 4.71e-07 GO:0032403 protein complex binding
1.62 8.07e-07 GO:0060589 nucleoside-triphosphatase regulator activity
1.71 2.35e-06 GO:0003779 actin binding
2.34 2.41e-06 GO:0030165 PDZ domain binding
1.61 2.74e-06 GO:0030695 GTPase regulator activity
1.73 1.86e-05 GO:0005083 small GTPase regulator activity
1.58 1.94e-05 GO:0015267 channel activity
1.44 2.01e-05 GO:0015075 ion transmembrane transporter activity
1.69 2.18e-05 GO:0022836 gated channel activity
1.57 2.30e-05 GO:0022803 passive transmembrane transporter activity
1.34 2.32e-05 GO:0005215 transporter activity
1.37 2.49e-05 GO:0022892 substrate-specific transporter activity
2.50 2.58e-05 GO:0019902 phosphatase binding
1.59 3.06e-05 GO:0005216 ion channel activity
1.34 4.93e-05 GO:0005102 receptor binding
1.57 6.32e-05 GO:0022838 substrate-specific channel activity
1.49 9.92e-05 GO:0008324 cation transmembrane transporter activity
1.60 2.40e-04 GO:0008047 enzyme activator activity
1.24 3.53e-04 GO:0046914 transition metal ion binding
1.78 3.89e-04 GO:0005244 voltage-gated ion channel activity
1.78 3.89e-04 GO:0022832 voltage-gated channel activity
1.36 3.89e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.64 6.41e-04 GO:0005261 cation channel activity
1.34 7.03e-04 GO:0022857 transmembrane transporter activity
1.90 8.15e-04 GO:0022843 voltage-gated cation channel activity
2.02 1.09e-03 GO:0008201 heparin binding
1.34 1.16e-03 GO:0016301 kinase activity
1.86 1.26e-03 GO:0005539 glycosaminoglycan binding
1.91 1.49e-03 GO:0005516 calmodulin binding
1.31 1.57e-03 GO:0030528 transcription regulator activity
1.39 2.62e-03 GO:0004672 protein kinase activity
2.84 2.73e-03 GO:0035254 glutamate receptor binding
1.33 3.05e-03 GO:0042802 identical protein binding
1.24 3.31e-03 GO:0008270 zinc ion binding
1.34 3.97e-03 GO:0046983 protein dimerization activity
3.99 7.98e-03 GO:0048407 platelet-derived growth factor binding
2.39 8.42e-03 GO:0051219 phosphoprotein binding
1.63 9.62e-03 GO:0005096 GTPase activator activity
2.59 1.08e-02 GO:0005518 collagen binding
1.73 1.12e-02 GO:0001871 pattern binding
1.73 1.12e-02 GO:0030247 polysaccharide binding
1.33 1.14e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.87 1.14e-02 GO:0031267 small GTPase binding
1.97 1.23e-02 GO:0005249 voltage-gated potassium channel activity
2.26 1.31e-02 GO:0019903 protein phosphatase binding
1.50 1.50e-02 GO:0019900 kinase binding
1.17 1.63e-02 GO:0000166 nucleotide binding
1.68 1.78e-02 GO:0008022 protein C-terminus binding
3.05 1.98e-02 GO:0005520 insulin-like growth factor binding
1.46 2.19e-02 GO:0016563 transcription activator activity
1.78 2.82e-02 GO:0005267 potassium channel activity
1.78 2.82e-02 GO:0051020 GTPase binding
3.11 2.89e-02 GO:0035255 ionotropic glutamate receptor binding
2.03 2.92e-02 GO:0019199 transmembrane receptor protein kinase activity
1.42 3.84e-02 GO:0030246 carbohydrate binding
2.39 4.85e-02 GO:0019208 phosphatase regulator activity