Motif ID: GUAAACA

Z-value: 1.473


Mature miRNA associated with seed GUAAACA:

NamemiRBase Accession
mmu-miR-30a MIMAT0000128
mmu-miR-30b MIMAT0000130
mmu-miR-30c MIMAT0000514
mmu-miR-30d MIMAT0000515
mmu-miR-30e MIMAT0000248
mmu-miR-384-5p MIMAT0004745



Activity profile for motif GUAAACA.

activity profile for motif GUAAACA


Sorted Z-values histogram for motif GUAAACA

Sorted Z-values for motif GUAAACA



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAAACA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_51965912 14.546 NM_001163631
Satb1
special AT-rich sequence binding protein 1
chr17_-_51972514 14.454 NM_001163632
Satb1
special AT-rich sequence binding protein 1
chr2_-_18919637 13.640 NM_008845
Pip4k2a
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr17_-_51971946 13.534 NM_009122
Satb1
special AT-rich sequence binding protein 1
chr17_-_51951378 13.442 NM_001163630
Satb1
special AT-rich sequence binding protein 1
chr7_+_90015842 11.920 NM_175366
Mex3b
mex3 homolog B (C. elegans)
chr15_-_96472392 11.085 NM_134086
Slc38a1
solute carrier family 38, member 1
chr15_-_96473193 10.890 NM_001166458
Slc38a1
solute carrier family 38, member 1
chr11_-_116274264 10.401 NM_027258
Rnf157
ring finger protein 157
chr4_+_32504409 10.282 NM_001109661
Bach2
BTB and CNC homology 2
chr1_-_74590801 10.183 NM_176972
Usp37
ubiquitin specific peptidase 37
chr13_+_91600662 10.049 NM_024186
NM_024272
Ssbp2

single-stranded DNA binding protein 2

chr2_+_112106470 10.034 NM_133649
Slc12a6
solute carrier family 12, member 6
chrX_-_54591905 9.712 NM_152801
Arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_119539909 9.698 NM_001166385
NM_009239
Sp4

trans-acting transcription factor 4

chr9_+_74918979 9.614 NM_010864
Myo5a
myosin VA
chr9_+_57556346 9.332 NM_153799
Edc3
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
chr7_+_95578782 9.145 NM_028238
Rab38
RAB38, member of RAS oncogene family
chr1_+_138027943 8.984 NM_001039472
Kif21b
kinesin family member 21B
chr8_-_112692071 8.955 NM_007586
Calb2
calbindin 2
chr1_+_132613903 8.871 NM_178691
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr7_+_133991066 8.684 NM_010069
Doc2a
double C2, alpha
chr8_+_73796512 8.532 NM_001142322
NM_001142323
NM_015742
Myo9b


myosin IXb


chrX_+_82819294 8.429 NM_025729
Tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr5_+_72091188 8.336 NM_008069
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr2_-_73367455 7.991 NM_153138
Wipf1
WAS/WASL interacting protein family, member 1
chr6_+_8459595 7.975 NM_133236
Glcci1
glucocorticoid induced transcript 1
chrX_-_11657678 7.882 NM_029510
NM_175044
NM_175045
NM_175046
Bcor



BCL6 interacting corepressor



chr3_+_103083215 7.880 NM_001079830
NM_053170
Trim33

tripartite motif-containing 33

chr2_+_112124767 7.600 NM_133648
Slc12a6
solute carrier family 12, member 6
chr8_+_116729508 7.595 NM_173016
Vat1l
vesicle amine transport protein 1 homolog-like (T. californica)
chr1_+_129999868 7.590 NM_181750
R3hdm1
R3H domain 1 (binds single-stranded nucleic acids)
chr15_-_98711692 7.532 NM_026967
Rhebl1
Ras homolog enriched in brain like 1
chr16_+_19760300 7.515 NM_001159407
NM_001159408
NM_054052
B3gnt5


UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5


chr17_+_83750246 7.484 NM_001114361
NM_001114362
NM_199466
Eml4


echinoderm microtubule associated protein like 4


chr13_-_69878721 7.340 NM_001145162
Ube2ql1
ubiquitin-conjugating enzyme E2Q family-like 1
chr11_+_104469313 7.291 NM_016780
Itgb3
integrin beta 3
chr3_+_55586431 7.184 NM_010750
Mab21l1
mab-21-like 1 (C. elegans)
chr11_-_79317583 7.144 NM_019409
Omg
oligodendrocyte myelin glycoprotein
chr1_+_155500166 7.137 NM_026380
Rgs8
regulator of G-protein signaling 8
chrX_+_133584130 7.137 NM_146261
Fam199x
family with sequence similarity 199, X-linked
chr16_-_46010510 7.024 NM_001134480
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr6_+_118016385 7.017 NM_027526
Rasgef1a
RasGEF domain family, member 1A
chr4_-_82505534 6.902 NM_026647
Zdhhc21
zinc finger, DHHC domain containing 21
chr10_+_110601745 6.886 NM_001003717
NM_175489
Osbpl8

oxysterol binding protein-like 8

chr5_-_23536487 6.859 NM_053090
Fam126a
family with sequence similarity 126, member A
chr1_-_97564139 6.828 NM_001159745
NM_009183
St8sia4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr17_-_24826873 6.794 NM_011522
Syngr3
synaptogyrin 3
chr7_+_133415982 6.691 NM_145587
Sbk1
SH3-binding kinase 1
chr9_+_108728650 6.662 NM_080437
Celsr3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr16_-_92697567 6.570 NM_001111023
NM_009821
Runx1

runt related transcription factor 1

chr1_-_90598670 6.359 NM_177305
Arl4c
ADP-ribosylation factor-like 4C
chr10_-_9620837 6.342 NM_001081344
Stxbp5
syntaxin binding protein 5 (tomosyn)
chr11_+_117515548 6.261 NM_198022
Tnrc6c
trinucleotide repeat containing 6C
chr7_+_107376116 6.204 NM_027629
Pgm2l1
phosphoglucomutase 2-like 1
chr10_+_82092582 6.190 NM_011561
NM_172552
Tdg

Gm9855
thymine DNA glycosylase

thymine DNA glycosylase pseudogene
chr5_-_123214252 6.078 NM_145358
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr8_-_70342105 6.074 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr17_+_25325344 6.059 NM_001197024
Unkl
unkempt-like (Drosophila)
chr19_+_57435498 6.014 NM_145505
Fam160b1
family with sequence similarity 160, member B1
chr10_-_118677059 6.009 NM_027994
Cand1
cullin associated and neddylation disassociated 1
chr8_-_30330079 6.002 NM_153135
Unc5d
unc-5 homolog D (C. elegans)
chr6_-_58857000 5.980 NM_021432
Nap1l5
nucleosome assembly protein 1-like 5
chrX_-_119510890 5.978 NM_138742
Nap1l3
nucleosome assembly protein 1-like 3
chrX_-_11737471 5.954 NM_001168321
Bcor
2900008C10Rik
BCL6 interacting corepressor
RIKEN cDNA 2900008C10 gene
chr5_-_68238654 5.942 NM_001038999
NM_009727
Atp8a1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr12_+_90191833 5.923 NM_172544
Nrxn3
neurexin III
chr15_+_30102306 5.899 NM_008729
Ctnnd2
catenin (cadherin associated protein), delta 2
chr19_+_38339167 5.891 NM_020278
Lgi1
leucine-rich repeat LGI family, member 1
chr10_+_39089594 5.880 NM_001122892
NM_001122893
NM_008054
Fyn


Fyn proto-oncogene


chr14_-_55735114 5.855 NM_177049
Jph4
junctophilin 4
chr17_+_25359526 5.848 NM_028789
Unkl
unkempt-like (Drosophila)
chr12_-_109241423 5.838 NM_001079883
NM_021399
Bcl11b

B-cell leukemia/lymphoma 11B

chr6_-_112897259 5.792 NM_080448
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr12_+_12268901 5.763 NM_001146119
NM_029758
Fam49a

family with sequence similarity 49, member A

chr18_-_10610315 5.747 NM_001081222
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr4_-_109959366 5.738 NM_001163399
NM_010488
Elavl4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr4_-_110024513 5.733 NM_001163397
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_+_72116953 5.684 NM_001081195
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr6_+_86354212 5.681 NM_001164078
NM_001164079
NM_011585
Tia1


cytotoxic granule-associated RNA binding protein 1


chr3_+_136333733 5.600 NM_008913
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr3_+_94282752 5.512 NM_172434
Celf3
VCUGBP, Elav-like family member 3
chr2_-_66278870 5.488 NM_018733
Scn1a
sodium channel, voltage-gated, type I, alpha
chr6_-_113991945 5.479 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr10_-_80945445 5.474 NM_176954
Celf5
CUGBP, Elav-like family member 5
chr2_+_4322020 5.471 NM_001177843
Frmd4a
FERM domain containing 4A
chr18_+_78135191 5.465 NM_001195633
5430411K18Rik
RIKEN cDNA 5430411K18 gene
chr9_-_24307580 5.440 NM_172920
Dpy19l1
dpy-19-like 1 (C. elegans)
chr7_-_134164627 5.414 NM_001102563
Prrt2
proline-rich transmembrane protein 2
chr17_+_36002537 5.388 NM_001146711
2310014H01Rik
RIKEN cDNA 2310014H01 gene
chr8_-_37312569 5.372 NM_001081150
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr1_+_129670740 5.367 NM_028399
Ccnt2
cyclin T2
chr15_-_96472600 5.349 NM_001166456
Slc38a1
solute carrier family 38, member 1
chr2_-_66473008 5.315 NM_018852
Scn9a
sodium channel, voltage-gated, type IX, alpha
chr14_-_58508974 5.309 NM_029492
Zdhhc20
zinc finger, DHHC domain containing 20
chr8_-_9771020 5.308 NM_173446
Fam155a
family with sequence similarity 155, member A
chr16_+_87699143 5.263 NM_007520
Bach1
BTB and CNC homology 1
chr4_-_149050154 5.230 NM_001164051
Pik3cd
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr8_+_128822478 5.229 NM_175434
Slc35f3
solute carrier family 35, member F3
chr2_+_4073908 5.226 NM_172475
Frmd4a
FERM domain containing 4A
chr3_-_152003317 5.224 NM_001162375
NM_174868
Fam73a

family with sequence similarity 73, member A

chr11_-_97605846 5.220 NM_054051
Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr16_-_31201251 5.216 NM_030138
Acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr16_+_13358513 5.214 NM_153588
Mkl2
MKL/myocardin-like 2
chr2_+_65508501 5.193 NM_001099298
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr4_+_21703416 5.172 NM_152825
Usp45
ubiquitin specific petidase 45
chr18_+_63868337 5.135 NM_001014981
Wdr7
WD repeat domain 7
chr7_+_130267398 5.134 NM_144925
Tnrc6a
trinucleotide repeat containing 6a
chr4_+_151712739 5.126 NM_001081376
NM_029216
Chd5

chromodomain helicase DNA binding protein 5

chr1_+_60466462 5.095 NM_001198570
NM_001198571
NM_198127
Abi2


abl-interactor 2


chr5_+_97426665 5.091 NM_080708
Bmp2k
BMP2 inducible kinase
chr11_-_69227176 5.050 NM_001017426
Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr10_-_62342761 5.033 NM_027384
Tet1
tet oncogene 1
chr16_+_52031661 4.991 NM_001033238
Cblb
Casitas B-lineage lymphoma b
chr12_-_71448600 4.972 NM_001110202
NM_001110203
NM_053167
Trim9


tripartite motif-containing 9


chr4_+_122860705 4.965 NM_174998
Hpcal4
hippocalcin-like 4
chr10_+_4424140 4.957 NM_001161822
NM_019958
Rgs17

regulator of G-protein signaling 17

chr2_-_74416925 4.956 NM_001110209
NM_027133
Lnp

limb and neural patterns

chr18_-_25912453 4.928 NM_001146292
NM_001146293
NM_001146294
NM_001146295
NM_001174074
NM_133195
Celf4





CUGBP, Elav-like family member 4





chr11_-_17853850 4.881 NM_026576
Etaa1
Ewing's tumor-associated antigen 1
chr6_-_113841356 4.826 NM_001036684
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr9_+_26559146 4.824 NM_029792
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chrX_+_23270202 4.809 NM_175180
Wdr44
WD repeat domain 44
chr13_-_100874021 4.804 NM_001081061
Bdp1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr7_-_36587975 4.761 NM_177739
Zfp507
E130304I02Rik
zinc finger protein 507
RIKEN cDNA E130304I02 gene
chr4_+_137150067 4.754 NM_130879
Usp48
ubiquitin specific peptidase 48
chr9_-_49607164 4.749 NM_001081445
NM_001113204
NM_010875
Ncam1


neural cell adhesion molecule 1


chr4_-_109960078 4.745 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr13_+_41701584 4.702 NM_001163572
Tmem170b
transmembrane protein 170B
chr1_-_156946739 4.699 NM_010500
Ier5
immediate early response 5
chr3_-_109946355 4.679 NM_001163348
NM_001163349
NM_001163350
NM_001163351
NM_030699
NM_133488
Ntng1





netrin G1





chr15_+_99984826 4.606 NM_172819
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr2_+_4480799 4.596 NM_001177844
Frmd4a
FERM domain containing 4A
chr3_-_19164956 4.564 NM_008802
Pde7a
phosphodiesterase 7A
chr8_+_41393330 4.562 NM_030110
Efha2
EF-hand domain family, member A2
chr1_-_162281701 4.558 NM_001038621
Rabgap1l
RAB GTPase activating protein 1-like
chr7_-_59117613 4.551 NM_001115087
Fancf
Fanconi anemia, complementation group F
chr11_-_107331865 4.550 NM_145823
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr14_+_28435613 4.542 NM_177814
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr3_+_101814059 4.503 NM_178777
Nhlh2
nescient helix loop helix 2
chr1_-_108610861 4.486 NM_009741
NM_177410
Bcl2

B-cell leukemia/lymphoma 2

chr10_-_88720534 4.459 NM_178773
Ano4
anoctamin 4
chr7_-_140004777 4.454 NM_212473
Fam53b
family with sequence similarity 53, member B
chr17_+_70871444 4.433 NM_001128180
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr11_+_23156022 4.428 NM_001035226
NM_134014
Xpo1

exportin 1, CRM1 homolog (yeast)

chr1_-_78193381 4.421 NM_001159520
NM_008781
Pax3

paired box gene 3

chr17_+_49071906 4.390 NM_027452
Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chr2_+_112219335 4.389 NM_024254
2410042D21Rik
RIKEN cDNA 2410042D21 gene
chr10_+_19654195 4.364 NM_008580
Map3k5
mitogen-activated protein kinase kinase kinase 5
chr1_-_157820378 4.355 NM_001039184
Cep350
centrosomal protein 350
chr8_+_32222291 4.351 NM_175136
Rnf122
ring finger protein 122
chr10_-_110447050 4.311 NM_172554
Zdhhc17
zinc finger, DHHC domain containing 17
chr4_-_131817388 4.305 NM_001122992
NM_020273
Gmeb1

glucocorticoid modulatory element binding protein 1

chr2_+_164793487 4.290 NM_020333
Slc12a5
solute carrier family 12, member 5
chr4_-_91042997 4.258 NM_001177883
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr12_+_33063653 4.238 NM_001162903
2010109K11Rik
RIKEN cDNA 2010109K11 gene
chr4_-_155366696 4.222 NM_080445
B3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr16_-_92826307 4.215 NM_001111021
NM_001111022
Runx1

runt related transcription factor 1

chr1_+_165860156 4.203 NM_028776
Scyl3
SCY1-like 3 (S. cerevisiae)
chr9_-_96531911 4.201 NM_053268
Rasa2
RAS p21 protein activator 2
chr17_+_74738195 4.196 NM_001162870
NM_016962
Spast

spastin

chr2_-_120229789 4.153 NM_001110496
NM_001110497
NM_173734
Tmem87a


transmembrane protein 87A


chr11_-_4018706 4.126 NM_144520
Sec14l2
SEC14-like 2 (S. cerevisiae)
chr12_+_50483869 4.124 NM_001160112
NM_008241
Foxg1

forkhead box G1

chr8_-_85856284 4.074 NM_001170691
NM_178736
Elmod2

ELMO domain containing 2

chr4_-_91066674 4.045 NM_207685
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_+_94732677 4.027 NM_001081414
NM_001143834
Grm5

glutamate receptor, metabotropic 5

chr10_-_13194201 4.020 NM_001195065
Phactr2
phosphatase and actin regulator 2
chr4_-_91038729 4.017 NM_010486
NM_207686
Elavl2

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)

chr11_+_45869473 4.010 NM_009616
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr1_+_9838330 3.989 NM_001037759
Sgk3
serum/glucocorticoid regulated kinase 3
chrX_-_154036606 3.979 NM_172307
Mbtps2
membrane-bound transcription factor peptidase, site 2
chr9_+_72380046 3.977 NM_001033536
Rfx7
regulatory factor X, 7
chr17_-_80606644 3.947 NM_001195485
NM_001195486
NM_001195487
NM_146083
Srsf7



serine/arginine-rich splicing factor 7



chr7_-_139978601 3.937 NM_175268
Fam53b
family with sequence similarity 53, member B
chr17_+_36003527 3.933 NM_175242
2310014H01Rik
RIKEN cDNA 2310014H01 gene
chr3_-_78949796 3.931 NM_001099624
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr15_-_78548542 3.919 NM_183141
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr18_-_70212948 3.917 NM_030554
Rab27b
RAB27b, member RAS oncogene family
chr4_-_149075697 3.915 NM_001029837
Pik3cd
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr7_-_64765360 3.894 NM_176942
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr5_+_19413335 3.878 NM_001170745
NM_015823
Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chrX_-_48559008 3.828 NM_134163
Mbnl3
muscleblind-like 3 (Drosophila)
chr10_+_84039622 3.828 NM_146008
Tcp11l2
t-complex 11 (mouse) like 2
chr2_+_119500777 3.822 NM_030112
Rtf1
Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr2_-_165710128 3.814 NM_027230
Zmynd8
zinc finger, MYND-type containing 8
chr8_-_107155195 3.806 NM_019662
Rrad
Ras-related associated with diabetes
chr18_-_43847367 3.799 NM_001163637
Jakmip2
janus kinase and microtubule interacting protein 2
chr2_-_91803660 3.793 NM_138306
Dgkz
diacylglycerol kinase zeta
chr8_+_108692750 3.773 NM_178798
Slc7a6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
chr16_+_55973916 3.762 NM_173026
Zbtb11
zinc finger and BTB domain containing 11
chr9_-_75446888 3.751 NM_001038710
Tmod2
tropomodulin 2
chr13_+_99124196 3.748 NM_008242
Foxd1
forkhead box D1
chr9_-_75459125 3.747 NM_016711
Tmod2
tropomodulin 2
chr15_-_9070066 3.739 NM_013787
NM_145468
Skp2

S-phase kinase-associated protein 2 (p45)

chr4_-_120861138 3.714 NM_001081013
Rlf
rearranged L-myc fusion sequence
chr18_-_46358466 3.678 NM_001170855
Trim36
tripartite motif-containing 36
chr9_-_108092712 3.675 NM_007567
Bsn
bassoon
chr15_-_98701613 3.675 NM_001033276
Mll2
myeloid/lymphoid or mixed-lineage leukemia 2
chr2_-_139892477 3.658 NM_175225
NM_001159640
NM_001159641
Tasp1


taspase, threonine aspartase 1



Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.63 1.01e-14 GO:0044260 cellular macromolecule metabolic process
1.75 1.66e-13 GO:0060255 regulation of macromolecule metabolic process
1.86 5.65e-13 GO:0010468 regulation of gene expression
1.65 1.07e-12 GO:0019222 regulation of metabolic process
1.70 3.20e-12 GO:0080090 regulation of primary metabolic process
1.69 3.34e-12 GO:0031323 regulation of cellular metabolic process
1.81 1.37e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.88 1.70e-11 GO:0051252 regulation of RNA metabolic process
1.52 1.91e-11 GO:0043170 macromolecule metabolic process
1.79 3.49e-11 GO:0051171 regulation of nitrogen compound metabolic process
1.81 7.45e-11 GO:0010556 regulation of macromolecule biosynthetic process
1.82 8.70e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.75 4.66e-10 GO:0031326 regulation of cellular biosynthetic process
1.74 6.68e-10 GO:0009889 regulation of biosynthetic process
1.83 7.56e-10 GO:0006355 regulation of transcription, DNA-dependent
1.96 1.84e-09 GO:0006351 transcription, DNA-dependent
1.96 2.07e-09 GO:0032774 RNA biosynthetic process
1.40 3.86e-09 GO:0044237 cellular metabolic process
1.77 1.54e-08 GO:0016070 RNA metabolic process
1.60 8.57e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.88 1.08e-07 GO:0043412 macromolecule modification
1.91 1.28e-07 GO:0006464 protein modification process
1.67 1.44e-07 GO:0090304 nucleic acid metabolic process
1.37 1.56e-07 GO:0044238 primary metabolic process
2.48 1.06e-06 GO:0007154 cell communication
1.70 4.91e-06 GO:0071842 cellular component organization at cellular level
1.64 9.03e-06 GO:0034645 cellular macromolecule biosynthetic process
1.70 1.25e-05 GO:0048869 cellular developmental process
1.62 1.52e-05 GO:0009059 macromolecule biosynthetic process
1.60 1.57e-05 GO:0010467 gene expression
1.65 1.60e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.66 1.65e-05 GO:0044267 cellular protein metabolic process
1.63 1.75e-05 GO:0048519 negative regulation of biological process
1.67 1.99e-05 GO:0048523 negative regulation of cellular process
1.58 2.42e-05 GO:0048856 anatomical structure development
1.94 3.29e-05 GO:0007399 nervous system development
1.48 3.56e-05 GO:0034641 cellular nitrogen compound metabolic process
1.28 3.74e-05 GO:0008152 metabolic process
2.91 4.80e-05 GO:0019226 transmission of nerve impulse
2.91 4.80e-05 GO:0035637 multicellular organismal signaling
1.17 4.81e-05 GO:0009987 cellular process
1.68 5.99e-05 GO:0030154 cell differentiation
1.46 8.61e-05 GO:0006807 nitrogen compound metabolic process
1.49 1.11e-04 GO:0032502 developmental process
1.58 1.80e-04 GO:0048731 system development
2.11 2.90e-04 GO:0048699 generation of neurons
1.24 3.00e-04 GO:0050789 regulation of biological process
1.23 3.54e-04 GO:0065007 biological regulation
3.09 6.63e-04 GO:0016567 protein ubiquitination
1.24 8.14e-04 GO:0050794 regulation of cellular process
2.01 1.03e-03 GO:0022008 neurogenesis
2.94 1.04e-03 GO:0032446 protein modification by small protein conjugation
1.47 1.14e-03 GO:0007275 multicellular organismal development
2.45 1.39e-03 GO:0044265 cellular macromolecule catabolic process
2.32 1.80e-03 GO:0030030 cell projection organization
1.88 2.37e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.95 2.66e-03 GO:0048468 cell development
2.63 3.88e-03 GO:0070647 protein modification by small protein conjugation or removal
2.74 6.47e-03 GO:0006511 ubiquitin-dependent protein catabolic process
2.71 7.96e-03 GO:0045664 regulation of neuron differentiation
1.46 8.05e-03 GO:0019538 protein metabolic process
2.64 8.19e-03 GO:0044257 cellular protein catabolic process
2.54 8.29e-03 GO:0016568 chromatin modification
2.54 8.29e-03 GO:0031175 neuron projection development
2.37 8.35e-03 GO:0060284 regulation of cell development
2.68 9.74e-03 GO:0019941 modification-dependent protein catabolic process
1.66 9.76e-03 GO:0006996 organelle organization
1.44 1.00e-02 GO:0016043 cellular component organization
2.66 1.11e-02 GO:0043632 modification-dependent macromolecule catabolic process
2.20 1.27e-02 GO:0009057 macromolecule catabolic process
1.95 1.48e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.78 1.52e-02 GO:0050793 regulation of developmental process
1.41 1.61e-02 GO:0071840 cellular component organization or biogenesis
2.36 1.67e-02 GO:0006325 chromatin organization
2.59 1.75e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
4.58 1.81e-02 GO:0019228 regulation of action potential in neuron
2.28 1.85e-02 GO:0048666 neuron development
2.50 2.24e-02 GO:0048858 cell projection morphogenesis
1.95 2.43e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.24 2.50e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.42 2.92e-02 GO:0050767 regulation of neurogenesis
2.94 3.04e-02 GO:0016569 covalent chromatin modification
1.88 3.10e-02 GO:0009890 negative regulation of biosynthetic process
2.45 3.19e-02 GO:0030163 protein catabolic process
2.45 3.19e-02 GO:0032990 cell part morphogenesis
1.94 3.29e-02 GO:0010629 negative regulation of gene expression
3.41 3.35e-02 GO:0006814 sodium ion transport
1.38 4.02e-02 GO:0044249 cellular biosynthetic process
2.28 4.56e-02 GO:0007610 behavior
2.50 4.73e-02 GO:0018193 peptidyl-amino acid modification
1.85 4.74e-02 GO:0045595 regulation of cell differentiation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.28 1.73e-13 GO:0005622 intracellular
1.28 8.71e-13 GO:0044424 intracellular part
1.32 5.71e-12 GO:0043229 intracellular organelle
1.32 9.65e-12 GO:0043226 organelle
1.52 1.01e-11 GO:0005634 nucleus
1.15 1.13e-09 GO:0005623 cell
1.15 1.13e-09 GO:0044464 cell part
1.31 2.59e-09 GO:0043227 membrane-bounded organelle
1.31 3.20e-09 GO:0043231 intracellular membrane-bounded organelle
2.69 3.41e-07 GO:0045202 synapse
2.93 3.88e-06 GO:0044456 synapse part
2.31 3.55e-05 GO:0043005 neuron projection
1.50 9.02e-05 GO:0043234 protein complex
1.80 5.11e-04 GO:0042995 cell projection
2.06 5.67e-04 GO:0044451 nucleoplasm part
2.79 7.20e-04 GO:0030424 axon
1.39 1.57e-03 GO:0032991 macromolecular complex
3.49 2.14e-03 GO:0019717 synaptosome
22.30 2.24e-03 GO:0033268 node of Ranvier
13.94 3.57e-03 GO:0001518 voltage-gated sodium channel complex
1.20 3.67e-03 GO:0005737 cytoplasm
3.04 4.62e-03 GO:0031252 cell leading edge
1.73 6.98e-03 GO:0005654 nucleoplasm
3.66 1.48e-02 GO:0008021 synaptic vesicle
10.72 1.67e-02 GO:0034706 sodium channel complex
2.87 1.70e-02 GO:0034702 ion channel complex
3.49 2.48e-02 GO:0034703 cation channel complex
1.53 3.63e-02 GO:0031981 nuclear lumen
1.52 4.54e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.28 2.87e-13 GO:0005488 binding
1.60 1.98e-06 GO:0003676 nucleic acid binding
1.51 2.05e-06 GO:0046872 metal ion binding
1.88 2.55e-06 GO:0008270 zinc ion binding
1.49 4.87e-06 GO:0043169 cation binding
1.49 6.37e-06 GO:0043167 ion binding
1.70 2.73e-05 GO:0003677 DNA binding
1.33 3.11e-05 GO:0005515 protein binding
1.70 9.38e-05 GO:0046914 transition metal ion binding
1.97 1.11e-04 GO:0030528 transcription regulator activity
1.57 2.72e-04 GO:0000166 nucleotide binding
3.00 6.68e-04 GO:0016881 acid-amino acid ligase activity
3.11 9.73e-04 GO:0019787 small conjugating protein ligase activity
2.39 1.01e-03 GO:0016874 ligase activity
3.20 1.06e-03 GO:0004842 ubiquitin-protein ligase activity
17.42 1.17e-03 GO:0031402 sodium ion binding
2.79 1.55e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
11.95 1.91e-03 GO:0031420 alkali metal ion binding
2.49 3.59e-03 GO:0016564 transcription repressor activity
11.62 1.47e-02 GO:0005248 voltage-gated sodium channel activity
1.83 4.45e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor