Motif ID: GUAGUGU

Z-value: 1.625


Mature miRNA associated with seed GUAGUGU:

NamemiRBase Accession
mmu-miR-142-3p MIMAT0000155



Activity profile for motif GUAGUGU.

activity profile for motif GUAGUGU


Sorted Z-values histogram for motif GUAGUGU

Sorted Z-values for motif GUAGUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAGUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_66489416 35.585 NM_139065
Rbm47
RNA binding motif protein 47
chr2_-_169956719 32.621 NM_001033299
Zfp217
zinc finger protein 217
chr8_+_74659107 32.344 NM_001001491
Tpm4
tropomyosin 4
chr5_-_66543123 32.090 NM_001127382
Rbm47
RNA binding motif protein 47
chr5_-_66542161 29.477 NM_178446
Rbm47
RNA binding motif protein 47
chr15_-_99705812 27.293 NM_001113545
Lima1
LIM domain and actin binding 1
chr10_-_36858671 26.848 NM_008538
Marcks
myristoylated alanine rich protein kinase C substrate
chr15_-_99650502 26.790 NM_023063
Lima1
LIM domain and actin binding 1
chr17_-_31992708 26.388 NM_010831
Sik1
salt inducible kinase 1
chr7_+_52273317 26.080 NM_009101
Rras
Harvey rat sarcoma oncogene, subgroup R
chr12_-_56087322 24.019 NM_013815
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr2_-_169968174 23.910 NM_001159683
Zfp217
zinc finger protein 217
chr2_-_103143352 20.867 NM_007914
Ehf
ets homologous factor
chr15_+_10106992 20.234 NM_011169
Prlr
prolactin receptor
chr5_+_65361309 19.088 NM_026667
Fam114a1
family with sequence similarity 114, member A1
chr11_+_115685365 18.401 NM_145438
Llgl2
lethal giant larvae homolog 2 (Drosophila)
chr9_-_35007875 18.327 NM_001177845
Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
chr9_-_35007458 16.785 NM_001177847
NM_001177846
NM_054096
Tirap


toll-interleukin 1 receptor (TIR) domain-containing adaptor protein


chr13_-_114408704 16.770 NM_130796
Snx18
sorting nexin 18
chr18_+_66618186 16.281 NM_021451
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr3_-_115710131 14.776 NM_023214
Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr12_+_33638809 14.321 NM_013635
Sypl
synaptophysin-like protein
chr5_+_104183148 14.235 NM_133919
Aff1
AF4/FMR2 family, member 1
chr5_+_104183591 14.174 NM_001080798
Aff1
AF4/FMR2 family, member 1
chr12_+_33639034 13.955 NM_198710
Sypl
synaptophysin-like protein
chr15_-_94420206 13.789 NM_008971
Twf1
twinfilin, actin-binding protein, homolog 1 (Drosophila)
chr17_+_27194207 13.611 NM_080553
Itpr3
inositol 1,4,5-triphosphate receptor 3
chr2_+_6243767 13.595 NM_001080548
Usp6nl
USP6 N-terminal like
chr2_-_44968728 13.183 NM_015753
Zeb2
zinc finger E-box binding homeobox 2
chr10_-_88906629 12.899 NM_001033331
NM_001079876
Gas2l3

growth arrest-specific 2 like 3

chr15_-_102087673 12.412 NM_011244
Rarg
retinoic acid receptor, gamma
chr16_+_87699143 12.334 NM_007520
Bach1
BTB and CNC homology 1
chr15_-_83002624 12.172 NM_029787
Cyb5r3
cytochrome b5 reductase 3
chr15_-_73015345 12.133 NM_153178
Eif2c2
eukaryotic translation initiation factor 2C, 2
chr10_+_69559860 12.071 NM_001111121
Ccdc6
coiled-coil domain containing 6
chr8_-_82581887 11.570 NM_020259
Hhip
Hedgehog-interacting protein
chr9_-_90165508 11.555 NM_194334
Tbc1d2b
TBC1 domain family, member 2B
chr15_-_102076706 11.509 NM_001042727
Rarg
retinoic acid receptor, gamma
chr12_-_52792851 10.746 NM_001172098
NM_052973
Strn3

striatin, calmodulin binding protein 3

chr2_-_12223518 10.317 NM_001001309
Itga8
integrin alpha 8
chr2_+_6273778 9.908 NM_181399
Usp6nl
USP6 N-terminal like
chr13_+_81022644 9.805 NM_001042591
Arrdc3
arrestin domain containing 3
chr17_+_35958628 9.648 NM_133662
Ier3
immediate early response 3
chr15_+_7090525 9.632 NM_013584
Lifr
leukemia inhibitory factor receptor
chr14_-_73109722 9.546 NM_207636
Fndc3a
fibronectin type III domain containing 3A
chr7_-_151739579 9.501 NM_001033319
NM_001195086
Ppfia1

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1

chr8_-_124175827 9.473 NM_080855
Zcchc14
zinc finger, CCHC domain containing 14
chr3_+_21975544 9.412 NM_030732
Tbl1xr1
transducin (beta)-like 1X-linked receptor 1
chr18_-_39646734 9.234 NM_008173
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr5_+_123844794 8.902 NM_133917
NM_177582
Mlxip

MLX interacting protein

chrX_-_13423666 8.788 NM_009806
Cask
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr3_+_65332306 8.724 NM_178892
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr4_-_135577545 8.646 NM_013736
Tceb3
transcription elongation factor B (SIII), polypeptide 3
chr2_+_83564553 8.532 NM_008402
Itgav
integrin alpha V
chr11_+_75492764 8.509 NM_133656
Crk
v-crk sarcoma virus CT10 oncogene homolog (avian)
chr9_-_123760686 8.459 NM_148925
Fyco1
FYVE and coiled-coil domain containing 1
chr4_-_59562054 8.360 NM_144904
NM_178164
Rod1

ROD1 regulator of differentiation 1 (S. pombe)

chr3_+_9250566 8.339 NM_177660
Zbtb10
zinc finger and BTB domain containing 10
chr10_-_7675872 8.311 NM_138667
Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr11_+_20101587 8.201 NM_008996
Rab1
RAB1, member RAS oncogene family
chr14_+_14845004 8.119 NM_139227
Atxn7
ataxin 7
chr3_+_52072251 8.118 NM_019739
Foxo1
forkhead box O1
chr4_+_130219255 8.008 NM_001159603
NM_001159604
NM_001159605
NM_001159606
NM_030722
Pum1




pumilio 1 (Drosophila)




chr15_-_77672472 7.983 NM_022410
Myh9
myosin, heavy polypeptide 9, non-muscle
chr5_-_149864518 7.927 NM_010439
Hmgb1
high mobility group box 1
chr13_+_113254277 7.590 NM_010560
Il6st
interleukin 6 signal transducer
chrX_-_138825032 7.549 NM_001033600
NM_019477
NM_207625
Acsl4


acyl-CoA synthetase long-chain family member 4


chr2_+_155207581 7.497 NM_178111
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr7_+_19679892 7.446 NM_011383
Six5
sine oculis-related homeobox 5 homolog (Drosophila)
chr10_-_119913990 7.305 NM_010441
Hmga2
high mobility group AT-hook 2
chr10_-_80813067 7.193 NM_001163165
NM_010440
Hmg20b

high mobility group 20 B

chr4_-_82151180 7.121 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr14_-_26588341 7.022 NM_001101433
Zcchc24
zinc finger, CCHC domain containing 24
chr10_-_80813198 6.999 NM_001163166
Hmg20b
high mobility group 20 B
chr9_-_44689356 6.970 NM_001081049
Mll1
myeloid/lymphoid or mixed-lineage leukemia 1
chr8_-_83404377 6.752 NM_021356
Gab1
growth factor receptor bound protein 2-associated protein 1
chr18_-_14841294 6.462 NM_001161369
NM_001161370
NM_001161371
NM_009280
Ss18



synovial sarcoma translocation, Chromosome 18



chr17_+_83750246 6.453 NM_001114361
NM_001114362
NM_199466
Eml4


echinoderm microtubule associated protein like 4


chr1_+_141318927 6.357 NM_172643
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr9_-_42913797 6.324 NM_027144
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chr10_+_21714471 6.014 NM_011361
Sgk1
serum/glucocorticoid regulated kinase 1
chr17_+_53706283 5.796 NM_020005
Kat2b
K(lysine) acetyltransferase 2B
chr17_-_84587278 5.791 NM_001001806
Zfp36l2
zinc finger protein 36, C3H type-like 2
chrX_-_53851046 5.778 NM_146234
Mmgt1
membrane magnesium transporter 1
chr4_+_116393559 5.660 NM_146151
Tesk2
testis-specific kinase 2
chr9_-_50817077 5.641 NM_178710
Sik2
salt inducible kinase 2
chr13_+_37980739 5.571 NM_001177869
Rreb1
ras responsive element binding protein 1
chr10_+_21601968 5.571 NM_001161845
Sgk1
serum/glucocorticoid regulated kinase 1
chr8_-_112261607 5.418 NM_001080930
Atxn1l
ataxin 1-like
chr12_-_92828018 5.331 NM_031391
Gtf2a1
general transcription factor II A, 1
chr10_+_70810540 5.311 NM_027184
Ipmk
inositol polyphosphate multikinase
chr15_-_6824238 5.287 NM_011019
Osmr
oncostatin M receptor
chr11_-_77421308 5.144 NM_144825
Taok1
TAO kinase 1
chr5_+_144165482 5.099 NM_025841
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr15_-_50721552 5.024 NM_032000
Trps1
trichorhinophalangeal syndrome I (human)
chr6_-_39675456 4.929 NM_139294
Braf
Braf transforming gene
chr3_-_144382959 4.926 NM_019464
Sh3glb1
SH3-domain GRB2-like B1 (endophilin)
chr5_-_144288812 4.847 NM_009007
Rac1
RAS-related C3 botulinum substrate 1
chr10_+_21705909 4.775 NM_001161848
Sgk1
serum/glucocorticoid regulated kinase 1
chr10_-_126725826 4.708 NM_033072
Mbd6
methyl-CpG binding domain protein 6
chr19_+_16207300 4.595 NM_008139
Gnaq
guanine nucleotide binding protein, alpha q polypeptide
chr17_-_32525894 4.589 NM_011717
Wiz
widely-interspaced zinc finger motifs
chr10_+_66590005 4.541 NM_207221
Jmjd1c
jumonji domain containing 1C
chr16_+_10488270 4.514 NM_007575
Ciita
class II transactivator
chr1_-_37592976 4.503 NM_173870
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr4_-_150432002 4.398 NM_009498
Vamp3
vesicle-associated membrane protein 3
chr11_+_83116148 4.385 NM_001035854
NM_027915
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chrX_-_71269249 4.379 NM_001177975
NM_001177973
NM_001177974
NM_001177976
NM_008363
Irak1




interleukin-1 receptor-associated kinase 1




chr10_+_21698470 4.377 NM_001161847
Sgk1
serum/glucocorticoid regulated kinase 1
chr2_+_52716901 4.192 NM_172409
Fmnl2
formin-like 2
chr11_+_94491055 4.178 NM_133807
Lrrc59
leucine rich repeat containing 59
chr10_+_21712008 4.044 NM_001161849
Sgk1
serum/glucocorticoid regulated kinase 1
chr16_-_35769389 4.032 NM_153550
Dirc2
disrupted in renal carcinoma 2 (human)
chr1_-_188529867 3.925 NM_009367
Tgfb2
transforming growth factor, beta 2
chrX_-_139401258 3.807 NM_019496
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr10_+_21713669 3.805 NM_001161850
Sgk1
serum/glucocorticoid regulated kinase 1
chr10_-_12581443 3.675 NM_011682
Utrn
utrophin
chr2_-_23011403 3.620 NM_025979
Mastl
microtubule associated serine/threonine kinase-like
chrX_+_98449866 3.503 NM_018789
Foxo4
forkhead box O4
chr15_-_82054741 3.453 NM_028075
Tnfrsf13c
tumor necrosis factor receptor superfamily, member 13c
chr17_+_53723450 3.422 NM_001190846
Kat2b
K(lysine) acetyltransferase 2B
chr1_+_55188086 3.408 NM_025283
Mobkl3
MOB1, Mps One Binder kinase activator-like 3 (yeast)
chr7_+_146574969 3.378 NM_001127363
NM_183144
Inpp5a

inositol polyphosphate-5-phosphatase A

chr11_-_88579517 3.339 NM_054043
Msi2
Musashi homolog 2 (Drosophila)
chr7_-_151656610 3.294 NM_007803
Cttn
cortactin
chrX_-_6765768 3.289 NM_016691
Clcn5
chloride channel 5
chr13_+_51503986 3.270 NM_010101
S1pr3
sphingosine-1-phosphate receptor 3
chr4_+_47366162 3.220 NM_009370
Tgfbr1
transforming growth factor, beta receptor I
chr19_+_5689130 3.014 NM_022012
Map3k11
mitogen-activated protein kinase kinase kinase 11
chr6_-_115944822 2.946 NM_026376
Plxnd1
plexin D1
chr5_+_43624701 2.945 NM_001177379
NM_175937
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chr9_-_14419410 2.941 NM_001081395
Amotl1
angiomotin-like 1
chr2_+_48669628 2.884 NM_007396
Acvr2a
activin receptor IIA
chr16_+_45224449 2.832 NM_001037719
NM_177584
Btla

B and T lymphocyte associated

chr12_-_55963776 2.813 NM_007688
Cfl2
cofilin 2, muscle
chr2_-_153355706 2.795 NM_001134300
8430427H17Rik
RIKEN cDNA 8430427H17 gene
chr5_-_143579060 2.501 NM_001122730
NM_178242
Tnrc18

trinucleotide repeat containing 18

chr4_+_148178500 2.401 NM_001159344
NM_027195
Casz1

castor homolog 1, zinc finger (Drosophila)

chr7_+_3646102 2.325 NM_024168
Tsen34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr1_-_167124442 2.208 NM_145512
Sft2d2
SFT2 domain containing 2
chr4_+_101390011 2.113 NM_001122899
NM_010704
NM_146146
Lepr


leptin receptor


chr2_+_22924561 2.077 NM_001102437
NM_001102438
Acbd5

acyl-Coenzyme A binding domain containing 5

chr11_+_77796215 1.922 NM_174852
Phf12
PHD finger protein 12
chr12_+_112812710 1.914 NM_021516
NM_022801
Mark3

MAP/microtubule affinity-regulating kinase 3

chr7_-_123182257 1.841 NM_001025559
Sox6
SRY-box containing gene 6
chr1_+_153602492 1.781 NM_001039644
Edem3
ER degradation enhancer, mannosidase alpha-like 3
chr17_+_34066835 1.742 NM_009059
Rgl2
ral guanine nucleotide dissociation stimulator-like 2
chr3_-_122322556 1.690 NM_001114665
NM_153118
Fnbp1l

formin binding protein 1-like

chr9_-_110310638 1.596 NM_001081043
Ptpn23
protein tyrosine phosphatase, non-receptor type 23
chr7_+_52104591 1.585 NM_026270
Akt1s1
AKT1 substrate 1 (proline-rich)
chr8_+_109674517 1.584 NM_025558
Cyb5b
cytochrome b5 type B
chr8_+_90806890 1.572 NM_001109756
Adcy7
adenylate cyclase 7
chr11_+_23156022 1.560 NM_001035226
NM_134014
Xpo1

exportin 1, CRM1 homolog (yeast)

chr11_+_20991321 1.532 NM_023324
Peli1
pellino 1
chr7_+_97278722 1.505 NM_146194
Picalm
phosphatidylinositol binding clathrin assembly protein
chr14_+_31638767 1.502 NM_028839
Tmem110
transmembrane protein 110
chr6_+_136467315 1.484 NM_019426
Atf7ip
activating transcription factor 7 interacting protein
chr11_-_69672218 1.462 NM_031880
Tnk1
tyrosine kinase, non-receptor, 1
chr1_+_59538966 1.433 NM_008057
Fzd7
frizzled homolog 7 (Drosophila)
chr15_-_3945704 1.386 NM_145930
AW549877
expressed sequence AW549877
chr8_-_36028698 1.342 NM_175091
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chrX_+_66613505 1.330 NM_008032
Aff2
AF4/FMR2 family, member 2
chr11_-_95926589 1.330 NM_172300
Ube2z
ubiquitin-conjugating enzyme E2Z (putative)
chr1_+_133807034 1.317 NM_001145804
NM_175294
Nucks1

nuclear casein kinase and cyclin-dependent kinase substrate 1

chr16_-_64786146 1.233 NM_028059
Zfp654
zinc finger protein 654
chr4_+_99602038 1.164 NM_028132
Pgm2
phosphoglucomutase 2
chr8_+_90818102 1.138 NM_001037724
Adcy7
adenylate cyclase 7
chr8_+_90796301 1.126 NM_007406
Adcy7
adenylate cyclase 7
chr3_-_51129908 1.108 NM_023502
Elf2
E74-like factor 2
chr12_+_113052385 1.107 NM_026752
Zfyve21
zinc finger, FYVE domain containing 21
chr8_+_90812964 1.044 NM_001037723
Adcy7
adenylate cyclase 7
chrX_-_7318412 1.004 NM_207202
Ccdc120
coiled-coil domain containing 120
chr10_-_105011439 0.994 NM_177368
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr7_-_72516109 0.956 NM_001163574
NM_009386
Tjp1

tight junction protein 1

chr12_-_52930506 0.947 NM_144788
Hectd1
HECT domain containing 1
chrX_+_126284271 0.910 NM_172493
Diap2
diaphanous homolog 2 (Drosophila)
chr8_+_113370907 0.890 NM_133973
Cog4
component of oligomeric golgi complex 4
chr17_-_32524703 0.859 NM_212438
Wiz
widely-interspaced zinc finger motifs
chr4_+_32504409 0.844 NM_001109661
Bach2
BTB and CNC homology 2
chr1_-_156946739 0.837 NM_010500
Ier5
immediate early response 5
chr1_+_129670740 0.738 NM_028399
Ccnt2
cyclin T2
chr17_-_66868909 0.725 NM_024448
Rab12
RAB12, member RAS oncogene family
chr7_-_71083734 0.653 NM_021366
Klf13
Kruppel-like factor 13
chr7_-_123174560 0.628 NM_001025560
Sox6
SRY-box containing gene 6
chr19_+_12040311 0.552 NM_001033174
Osbp
oxysterol binding protein
chr1_+_182656137 0.517 NM_133225
Acbd3
acyl-Coenzyme A binding domain containing 3
chr9_+_54765084 0.387 NM_177351
Agphd1
aminoglycoside phosphotransferase domain containing 1
chr17_-_10512217 0.360 NM_001159516
NM_001159517
NM_021881
Qk


quaking


chr11_+_80242103 0.342 NM_178616
Psmd11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr2_-_166821559 0.326 NM_001109905
NM_001109906
NM_011490
Stau1


staufen (RNA binding protein) homolog 1 (Drosophila)


chr7_-_123138599 0.214 NM_011445
Sox6
SRY-box containing gene 6
chr9_-_114843103 0.165 NM_175380
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr7_+_3645211 0.092 NM_001164204
NM_001164205
Tsen34

tRNA splicing endonuclease 34 homolog (S. cerevisiae)

chr6_+_71493841 0.091 NM_025783
Vps24
vacuolar protein sorting 24 (yeast)
chr17_+_36053855 0.069 NM_175934
Ppp1r10
protein phosphatase 1, regulatory subunit 10
chr2_-_38920925 0.003 NM_029793
Golga1
golgi autoantigen, golgin subfamily a, 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.67 9.36e-15 GO:0031323 regulation of cellular metabolic process
2.58 3.97e-13 GO:0080090 regulation of primary metabolic process
2.39 2.94e-12 GO:0019222 regulation of metabolic process
2.53 1.30e-11 GO:0060255 regulation of macromolecule metabolic process
2.49 4.18e-08 GO:0009889 regulation of biosynthetic process
2.49 6.54e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.30 7.42e-08 GO:0009893 positive regulation of metabolic process
2.46 9.74e-08 GO:0051171 regulation of nitrogen compound metabolic process
2.52 1.11e-07 GO:0010556 regulation of macromolecule biosynthetic process
3.33 2.19e-07 GO:0031325 positive regulation of cellular metabolic process
1.98 2.45e-07 GO:0044260 cellular macromolecule metabolic process
2.43 2.70e-07 GO:0031326 regulation of cellular biosynthetic process
2.44 3.54e-07 GO:0010468 regulation of gene expression
1.64 4.49e-07 GO:0050794 regulation of cellular process
3.29 5.44e-07 GO:0010604 positive regulation of macromolecule metabolic process
2.46 1.06e-06 GO:0048522 positive regulation of cellular process
2.43 1.52e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.55 2.63e-06 GO:0065007 biological regulation
2.30 4.20e-06 GO:0048518 positive regulation of biological process
2.44 5.33e-06 GO:0051252 regulation of RNA metabolic process
1.57 5.61e-06 GO:0050789 regulation of biological process
2.73 8.64e-06 GO:0006351 transcription, DNA-dependent
2.51 8.74e-06 GO:0048523 negative regulation of cellular process
2.72 9.08e-06 GO:0032774 RNA biosynthetic process
1.81 1.22e-05 GO:0043170 macromolecule metabolic process
4.16 1.46e-05 GO:0019220 regulation of phosphate metabolic process
4.16 1.46e-05 GO:0051174 regulation of phosphorus metabolic process
2.39 1.49e-05 GO:0048519 negative regulation of biological process
2.38 2.65e-05 GO:0006355 regulation of transcription, DNA-dependent
2.35 3.66e-05 GO:0016070 RNA metabolic process
4.13 3.72e-05 GO:0042325 regulation of phosphorylation
3.52 4.00e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
3.38 4.49e-05 GO:0032268 regulation of cellular protein metabolic process
3.34 5.96e-05 GO:0009891 positive regulation of biosynthetic process
1.64 6.98e-05 GO:0044238 primary metabolic process
3.20 7.35e-05 GO:0051246 regulation of protein metabolic process
1.64 1.36e-04 GO:0044237 cellular metabolic process
3.27 1.59e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.12 2.02e-04 GO:0016043 cellular component organization
3.21 2.22e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.95 2.22e-04 GO:0009966 regulation of signal transduction
2.59 3.34e-04 GO:0048583 regulation of response to stimulus
3.05 3.38e-04 GO:0010033 response to organic substance
3.28 4.94e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.47 6.48e-04 GO:0031399 regulation of protein modification process
2.02 7.53e-04 GO:0071840 cellular component organization or biogenesis
3.20 7.61e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
3.30 8.05e-04 GO:0010628 positive regulation of gene expression
3.87 9.33e-04 GO:0001932 regulation of protein phosphorylation
3.15 9.88e-04 GO:0042127 regulation of cell proliferation
1.31 9.96e-04 GO:0009987 cellular process
4.17 1.48e-03 GO:0071310 cellular response to organic substance
2.04 1.97e-03 GO:0090304 nucleic acid metabolic process
1.92 2.79e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.42 2.87e-03 GO:0006468 protein phosphorylation
2.54 2.91e-03 GO:0023051 regulation of signaling
3.27 3.03e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.58 3.14e-03 GO:0009653 anatomical structure morphogenesis
4.44 3.32e-03 GO:0010627 regulation of intracellular protein kinase cascade
2.05 3.35e-03 GO:0010467 gene expression
3.22 3.81e-03 GO:0051254 positive regulation of RNA metabolic process
2.86 4.94e-03 GO:0006796 phosphate metabolic process
2.86 5.12e-03 GO:0006793 phosphorus metabolic process
4.27 5.23e-03 GO:0043549 regulation of kinase activity
3.27 5.45e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.47 7.86e-03 GO:0008152 metabolic process
4.09 8.52e-03 GO:0051338 regulation of transferase activity
3.05 8.67e-03 GO:0016310 phosphorylation
3.44 8.98e-03 GO:0045892 negative regulation of transcription, DNA-dependent
3.29 9.18e-03 GO:0010629 negative regulation of gene expression
2.04 9.88e-03 GO:0034645 cellular macromolecule biosynthetic process
1.96 1.00e-02 GO:0048856 anatomical structure development
4.03 1.01e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
4.31 1.04e-02 GO:0009725 response to hormone stimulus
3.39 1.10e-02 GO:0051253 negative regulation of RNA metabolic process
5.65 1.12e-02 GO:0043408 regulation of MAPKKK cascade
2.80 1.12e-02 GO:0031324 negative regulation of cellular metabolic process
3.23 1.18e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.02 1.20e-02 GO:0009059 macromolecule biosynthetic process
3.09 1.21e-02 GO:0009890 negative regulation of biosynthetic process
4.21 1.35e-02 GO:0045859 regulation of protein kinase activity
15.94 1.36e-02 GO:0043507 positive regulation of JUN kinase activity
4.96 1.40e-02 GO:0033674 positive regulation of kinase activity
2.37 1.50e-02 GO:0065009 regulation of molecular function
8.70 1.53e-02 GO:0070302 regulation of stress-activated protein kinase signaling cascade
3.46 1.60e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.76 1.92e-02 GO:0006807 nitrogen compound metabolic process
3.24 1.94e-02 GO:0070887 cellular response to chemical stimulus
4.78 1.98e-02 GO:0051347 positive regulation of transferase activity
1.77 2.02e-02 GO:0034641 cellular nitrogen compound metabolic process
2.54 2.31e-02 GO:0050790 regulation of catalytic activity
8.10 2.43e-02 GO:0019221 cytokine-mediated signaling pathway
1.82 2.43e-02 GO:0009058 biosynthetic process
2.90 2.88e-02 GO:0009790 embryo development
2.63 2.97e-02 GO:0035556 intracellular signal transduction
3.00 3.10e-02 GO:0031327 negative regulation of cellular biosynthetic process
3.26 3.19e-02 GO:0016192 vesicle-mediated transport
3.83 3.60e-02 GO:0009719 response to endogenous stimulus
1.79 3.62e-02 GO:0032502 developmental process
3.09 3.66e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.18 3.77e-02 GO:0043412 macromolecule modification
2.21 3.94e-02 GO:0006464 protein modification process
4.07 3.99e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.58 4.01e-02 GO:0009892 negative regulation of metabolic process
3.04 4.42e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
12.55 4.46e-02 GO:0043506 regulation of JUN kinase activity

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.57 1.43e-13 GO:0005622 intracellular
1.54 1.33e-11 GO:0044424 intracellular part
1.29 4.23e-10 GO:0005623 cell
1.29 4.23e-10 GO:0044464 cell part
1.54 8.72e-08 GO:0043229 intracellular organelle
1.53 1.07e-07 GO:0043226 organelle
1.58 2.74e-07 GO:0043231 intracellular membrane-bounded organelle
1.58 3.12e-07 GO:0043227 membrane-bounded organelle
1.82 2.41e-06 GO:0005634 nucleus
1.47 1.88e-04 GO:0005737 cytoplasm
1.73 9.38e-04 GO:0044422 organelle part
1.74 1.11e-03 GO:0044446 intracellular organelle part
2.84 1.46e-03 GO:0005794 Golgi apparatus
2.31 5.60e-03 GO:0031981 nuclear lumen
1.84 9.82e-03 GO:0043234 protein complex
2.15 1.01e-02 GO:0070013 intracellular organelle lumen
2.15 1.04e-02 GO:0043233 organelle lumen
1.51 1.33e-02 GO:0044444 cytoplasmic part
2.10 1.50e-02 GO:0031974 membrane-enclosed lumen
2.45 2.92e-02 GO:0005654 nucleoplasm
78.63 3.18e-02 GO:0005900 oncostatin-M receptor complex
2.28 3.67e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.58 1.33e-13 GO:0005488 binding
2.25 8.40e-06 GO:0003676 nucleic acid binding
1.71 1.25e-05 GO:0005515 protein binding
4.10 1.59e-03 GO:0004674 protein serine/threonine kinase activity
5.17 1.80e-03 GO:0019901 protein kinase binding
2.23 2.30e-03 GO:0003677 DNA binding
3.44 3.22e-03 GO:0004672 protein kinase activity
2.90 5.74e-03 GO:0016301 kinase activity
3.06 7.89e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
4.33 9.30e-03 GO:0019900 kinase binding
2.69 9.85e-03 GO:0030528 transcription regulator activity
11.57 1.28e-02 GO:0004896 cytokine receptor activity
2.99 1.76e-02 GO:0043565 sequence-specific DNA binding
3.57 2.67e-02 GO:0008289 lipid binding
2.74 2.93e-02 GO:0001071 nucleic acid binding transcription factor activity
2.74 2.93e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
7.08 3.77e-02 GO:0019955 cytokine binding
78.63 3.90e-02 GO:0004897 ciliary neurotrophic factor receptor activity
2.59 3.92e-02 GO:0019899 enzyme binding
2.48 4.31e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.18 4.72e-02 GO:0008270 zinc ion binding
2.73 4.83e-02 GO:0046983 protein dimerization activity