• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: HMGA1,2.p2

Z-value: 1.428

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_45402907	62.425		Col3a1	collagen, type III, alpha 1
chr1_+_45368443	40.100		Col3a1	collagen, type III, alpha 1
chr1_+_45390415	31.580		Col3a1	collagen, type III, alpha 1
chr1_+_45401303	30.732		Col3a1	collagen, type III, alpha 1
chr6_+_4490515	27.579		Col1a2	collagen, type I, alpha 2
chr10_+_96944961	26.957	NM_007833	Dcn	decorin
chr6_+_4484651	21.361		Col1a2	collagen, type I, alpha 2
chr5_-_17394564	19.771		Cd36	CD36 antigen
chr3_-_10208575	17.049	NM_024406	Fabp4	fatty acid binding protein 4, adipocyte
chr12_+_110783593	16.842		Meg3	maternally expressed 3
chr8_-_87297283	16.411		Nfix	nuclear factor I/X
chr1_+_45368382	15.688	NM_009930	Col3a1	collagen, type III, alpha 1
chr1_-_172018982	14.341	NM_022563	Ddr2	discoidin domain receptor family, member 2
chr1_-_66991625	14.132	NM_021285	Myl1	myosin, light polypeptide 1
chr15_-_3421486	13.937	NM_001048147	Ghr	growth hormone receptor
chr9_-_117161564	13.793	NM_001172122 NM_001172123 NM_001172124 NM_001172126 NM_178660	Rbms3	RNA binding motif, single stranded interacting protein
chr5_-_17355533	13.092	NM_001159556 NM_001159557	Cd36	CD36 antigen
chr6_+_4483741	12.861		Col1a2	collagen, type I, alpha 2
chr12_+_110783786	12.771		Meg3	maternally expressed 3
chr1_-_66991580	12.702		Myl1	myosin, light polypeptide 1
chr2_+_131763454	12.671		Prnp	prion protein
chr14_-_104213981	12.607
chr6_+_34659440	12.558	NM_145575	Cald1	caldesmon 1
chr1_-_45559904	12.351		Col5a2	collagen, type V, alpha 2
chr11_-_55208276	12.335
chr2_-_110203264	12.099		Fibin	fin bud initiation factor homolog (zebrafish)
chr5_+_104864168	11.695		Spp1	secreted phosphoprotein 1
chr3_+_19857053	11.639	NM_001042611 NM_007752	Cp	ceruloplasmin
chr3_+_54165028	11.611	NM_001198765 NM_001198766 NM_015784	Postn	periostin, osteoblast specific factor
chr2_-_110203298	11.607		Fibin	fin bud initiation factor homolog (zebrafish)
chr1_-_82232392	11.546		Irs1	insulin receptor substrate 1
chr15_+_3230053	11.301
chr1_-_142079842	11.255	NM_009888	Cfh	complement component factor h
chr3_-_129035406	11.156	NM_007934	Enpep	glutamyl aminopeptidase
chr17_-_14831095	10.961		Thbs2	thrombospondin 2
chr5_+_90889937	10.894		Alb	albumin
chr10_+_87322774	10.496		Igf1	insulin-like growth factor 1
chr7_-_51920870	10.467	NM_028021	Myh14	myosin, heavy polypeptide 14
chr10_+_87321789	10.338	NM_001111275 NM_010512	Igf1	insulin-like growth factor 1
chr12_+_101447413	10.325		Calm1	calmodulin 1
chr5_+_90889913	10.278	NM_009654	Alb	albumin
chr16_-_85173930	10.273		App	amyloid beta (A4) precursor protein
chr1_-_72905107	10.149		Igfbp5	insulin-like growth factor binding protein 5
chr7_-_67149962	10.147	NM_013670 NM_033174	Snrpn Snurf	small nuclear ribonucleoprotein N SNRPN upstream reading frame
chr9_+_40590943	9.818		9030425E11Rik	RIKEN cDNA 9030425E11 gene
chr4_+_138012860	9.808		Camk2n1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr13_+_49703402	9.750	NM_008760	Ogn	osteoglycin
chr10_-_76172218	9.657		Col6a1	collagen, type VI, alpha 1
chr18_+_37906739	9.469	NM_033593	Pcdhga10	protocadherin gamma subfamily A, 10
chr16_-_85173944	9.333	NM_001198823 NM_001198824 NM_001198825 NM_001198826 NM_007471	App	amyloid beta (A4) precursor protein
chr4_-_76240202	9.193	NM_011211	Ptprd	protein tyrosine phosphatase, receptor type, D
chrX_-_91787372	9.028	NM_019791	Maged1	melanoma antigen, family D, 1
chr19_-_44470218	8.890		Scd1	stearoyl-Coenzyme A desaturase 1
chr16_-_85173978	8.767		App	amyloid beta (A4) precursor protein
chr1_-_71686889	8.588		Fn1	fibronectin 1
chr16_-_85173918	8.526		App	amyloid beta (A4) precursor protein
chr3_+_79690856	8.518		Fam198b	family with sequence similarity 198, member B
chr2_-_58368568	8.517		Acvr1	activin A receptor, type 1
chr17_-_14831233	8.471		Thbs2	thrombospondin 2
chr10_+_69487700	8.321		Ank3	ankyrin 3, epithelial
chr12_+_101447480	8.320		Calm1	calmodulin 1
chr14_+_27473359	8.201		Arf4	ADP-ribosylation factor 4
chr1_-_45560001	8.188	NM_007737	Col5a2	collagen, type V, alpha 2
chr5_+_75548337	8.142		Pdgfra	platelet derived growth factor receptor, alpha polypeptide
chr2_+_152512797	8.126	NM_025543	Mcts2	malignant T cell amplified sequence 2
chr2_+_136539143	8.053	NM_011428	Snap25	synaptosomal-associated protein 25
chr2_+_136539202	8.047		Snap25	synaptosomal-associated protein 25
chr10_+_24315247	7.972	NM_010217	Ctgf	connective tissue growth factor
chr8_-_11199802	7.961		Col4a1	collagen, type IV, alpha 1
chr10_+_87323855	7.958	NM_001111274 NM_001111276 NM_184052	Igf1	insulin-like growth factor 1
chr17_+_75578120	7.871	NM_206958	Ltbp1	latent transforming growth factor beta binding protein 1
chr7_-_110976499	7.698		Hbb-b1	hemoglobin, beta adult major chain
chr7_-_117509277	7.666		Sbf2	SET binding factor 2
chr7_-_148141821	7.637	NM_030694	Ifitm2	interferon induced transmembrane protein 2
chr3_-_144637974	7.611	NM_207208	Clca6	chloride channel calcium activated 6
chr3_-_113277601	7.492	NM_007446	Amy1	amylase 1, salivary
chr5_+_90890764	7.282		Alb	albumin
chr2_-_110203138	7.268	NM_026271	Fibin	fin bud initiation factor homolog (zebrafish)
chr3_-_57105840	7.265	NM_008536	Tm4sf1	transmembrane 4 superfamily member 1
chr5_-_104543106	7.261	NM_010097	Sparcl1	SPARC-like 1
chr16_-_85173851	7.126		App	amyloid beta (A4) precursor protein
chrX_+_135744582	7.121	NM_001164630 NM_175541	Mum1l1	melanoma associated antigen (mutated) 1-like 1
chr15_-_99609550	6.935		Lima1	LIM domain and actin binding 1
chr2_-_122420914	6.931		Gatm	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr2_-_140485267	6.911		Flrt3	fibronectin leucine rich transmembrane protein 3
chr6_-_122806122	6.906	NM_009779	C3ar1	complement component 3a receptor 1
chrX_-_132738383	6.906	NM_177919	Tceal5	transcription elongation factor A (SII)-like 5
chr9_-_15105864	6.845		4931406C07Rik	RIKEN cDNA 4931406C07 gene
chr6_+_56828743	6.842		Fkbp9	FK506 binding protein 9
chr17_-_14831262	6.817	NM_011581	Thbs2	thrombospondin 2
chr14_-_21277869	6.752		Anxa7	annexin A7
chr16_+_7409879	6.716		Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_+_89891661	6.646	NM_026433	Tmem100	transmembrane protein 100
chr15_-_8660442	6.603		Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_+_21230683	6.599		Gsta3	glutathione S-transferase, alpha 3
chr5_+_75548309	6.551	NM_011058	Pdgfra	platelet derived growth factor receptor, alpha polypeptide
chr1_-_66981900	6.539	NM_001113387	Myl1	myosin, light polypeptide 1
chr2_+_143768541	6.532		Dstn	destrin
chrX_+_93651684	6.496	NM_001159627 NM_181273	Heph	hephaestin
chr11_-_118163704	6.422		Timp2	tissue inhibitor of metalloproteinase 2
chr1_-_71642303	6.401		Fn1	fibronectin 1
chr2_+_145647868	6.304		Rin2	Ras and Rab interactor 2
chr5_-_104542641	6.235		Sparcl1	SPARC-like 1
chr15_-_8660729	6.199	NM_148938	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_+_121184667	6.191		Spon1	spondin 1, (f-spondin) extracellular matrix protein
chr2_+_145648290	6.045		Rin2	Ras and Rab interactor 2
chr12_+_37968225	6.028	NM_178767	Tmem195	transmembrane protein 195
chr9_-_15105965	5.972	NM_133732	4931406C07Rik	RIKEN cDNA 4931406C07 gene
chr16_+_34921598	5.925		Mylk	myosin, light polypeptide kinase
chr15_-_8660462	5.919		Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_122241909	5.894		Fnbp1l	formin binding protein 1-like
chr6_-_36761360	5.844	NM_008973	Ptn	pleiotrophin
chr14_+_63756868	5.741		Ctsb	cathepsin B
chr19_+_23239333	5.739		Klf9	Kruppel-like factor 9
chr16_-_84955086	5.723		App	amyloid beta (A4) precursor protein
chr2_-_84490666	5.705	NM_001085453	Ctnnd1	catenin (cadherin associated protein), delta 1
chr9_-_49311823	5.696		Ncam1	neural cell adhesion molecule 1
chr8_-_67071497	5.655
chr5_-_67009869	5.637	NM_009686	Apbb2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr15_+_3220766	5.603	NM_001042613 NM_001042614 NM_009155	Sepp1	selenoprotein P, plasma, 1
chr17_-_56419388	5.516		Plin3	perilipin 3
chr2_+_128604653	5.499		Mertk	c-mer proto-oncogene tyrosine kinase
chr15_-_96861590	5.489		Slc38a4	solute carrier family 38, member 4
chr9_+_43877511	5.485	NM_016808	Usp2	ubiquitin specific peptidase 2
chr17_-_14831058	5.468		Thbs2	thrombospondin 2
chr10_-_60227439	5.424		Unc5b	unc-5 homolog B (C. elegans)
chr17_+_43526389	5.423	NM_001081178	Gpr116	G protein-coupled receptor 116
chr1_+_151947225	5.406	NM_011198	Ptgs2	prostaglandin-endoperoxide synthase 2
chr8_-_49760037	5.371	NM_001145937 NM_011857	Odz3	odd Oz/ten-m homolog 3 (Drosophila)
chr2_+_72244049	5.311		B230120H23Rik	RIKEN cDNA B230120H23 gene
chr3_+_14863507	5.301	NM_007606	Car3	carbonic anhydrase 3
chr16_+_42955690	5.270		BC002163	NADH dehydrogenase Fe-S protein 5 pseudogene
chr4_-_142889372	5.266	NM_010329	Pdpn	podoplanin
chr9_+_110255447	5.265
chr18_+_20823908	5.259		Ttr	transthyretin
chr7_-_52230179	5.250		Cpt1c	carnitine palmitoyltransferase 1c
chr1_-_95518831	5.221		Stk25	serine/threonine kinase 25 (yeast)
chr7_+_27904997	5.218		Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2
chr10_+_97028456	5.200		Lum	lumican
chr19_+_23240506	5.199		Klf9	Kruppel-like factor 9
chr15_-_8660479	5.171		Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_+_110884340	5.142		Rian	RNA imprinted and accumulated in nucleus
chr2_+_71892681	5.134		Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4
chr12_+_32008372	5.127		Lamb1	laminin B1
chr4_-_60594469	5.078		Mup1	major urinary protein 1
chrX_+_20127488	5.067		Rgn	regucalcin
chr10_+_56107352	5.065		Gja1	gap junction protein, alpha 1
chr4_+_41709182	5.027	NM_010549	Il11ra1	interleukin 11 receptor, alpha chain 1
chr4_-_61179982	5.027		Mup1	major urinary protein 1
chr10_-_83989221	4.998		Ckap4	cytoskeleton-associated protein 4
chr18_+_37896589	4.987	NM_033592	Pcdhga9	protocadherin gamma subfamily A, 9
chr3_-_97628441	4.958	NM_001110163	Pde4dip	phosphodiesterase 4D interacting protein (myomegalin)
chr5_-_104542598	4.943		Sparcl1	SPARC-like 1
chr18_+_37906668	4.930		Pcdhga10	protocadherin gamma subfamily A, 10
chr5_-_100812885	4.903		Sec31a	Sec31 homolog A (S. cerevisiae)
chr14_-_66572577	4.884	NM_172604	Scara3	scavenger receptor class A, member 3
chr1_-_72906185	4.859		Igfbp5	insulin-like growth factor binding protein 5
chr5_+_115916274	4.857	NM_011107	Pla2g1b	phospholipase A2, group IB, pancreas
chr14_+_51710846	4.841		Rnase4	ribonuclease, RNase A family 4
chr1_+_59543450	4.836
chr3_-_10208480	4.825		Fabp4 Fabp9	fatty acid binding protein 4, adipocyte fatty acid binding protein 9, testis
chr12_+_110779204	4.823		Meg3	maternally expressed 3
chr5_-_104542751	4.814		Sparcl1	SPARC-like 1
chrX_+_160811458	4.808	NM_010216	Figf	c-fos induced growth factor
chr5_-_67009992	4.748		Apbb2	amyloid beta (A4) precursor protein-binding, family B, member 2
chr5_-_17341534	4.689		Cd36	CD36 antigen
chr6_+_22825464	4.689	NM_001081306	Ptprz1	protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr4_-_60594496	4.667		Mup1	major urinary protein 1
chr4_-_98049833	4.645	NM_053157	Tm2d1	TM2 domain containing 1
chr5_-_17394776	4.638	NM_001159558	Cd36	CD36 antigen
chr19_-_21467250	4.620		Gda	guanine deaminase
chr14_+_51627425	4.611	NM_001162863	Rnase10	ribonuclease, RNase A family, 10 (non-active)
chr17_-_56419161	4.567		Plin3	perilipin 3
chr7_-_110976438	4.563		Hbb-b1	hemoglobin, beta adult major chain
chr17_+_75784448	4.529		Ltbp1	latent transforming growth factor beta binding protein 1
chr10_+_97028134	4.529	NM_008524	Lum	lumican
chr11_+_29640992	4.522		Rtn4	reticulon 4
chr3_-_148617598	4.519	NM_001081298	Lphn2	latrophilin 2
chr13_+_49704471	4.510		Ogn	osteoglycin
chr2_-_148701203	4.510	NM_009976	Cst3	cystatin C
chr7_-_110976314	4.509		Hbb-b1 Hbb-b2	hemoglobin, beta adult major chain hemoglobin, beta adult minor chain
chr5_-_104421860	4.505		Hsd17b11	hydroxysteroid (17-beta) dehydrogenase 11
chr6_-_122806042	4.483		C3ar1	complement component 3a receptor 1
chr15_+_91991704	4.482	NM_001159647	Cntn1	contactin 1
chr4_-_142889312	4.472		Pdpn	podoplanin
chr10_+_96945057	4.461		Dcn	decorin
chr17_-_12888210	4.448		Igf2r	insulin-like growth factor 2 receptor
chr13_+_3553690	4.432		Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2
chr14_+_76354807	4.425	NM_026214	Kctd4	potassium channel tetramerisation domain containing 4
chr18_+_37921454	4.403	NM_033580	Pcdhgb8	protocadherin gamma subfamily B, 8
chr10_+_68996455	4.380	NM_146005 NM_170688 NM_170689 NM_170690 NM_170728 NM_170729 NM_170730	Ank3	ankyrin 3, epithelial
chr7_+_19661548	4.354	NM_010058	Dmwd	dystrophia myotonica-containing WD repeat motif
chr19_-_34329804	4.333	NM_007392	Acta2	actin, alpha 2, smooth muscle, aorta
chr12_+_110806715	4.327		Meg3	maternally expressed 3
chr3_+_59835700	4.311	NM_023383	Aadac	arylacetamide deacetylase (esterase)
chr9_+_92502908	4.305		Plod2	procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
chr6_-_54543121	4.302	NM_153573	Fkbp14	FK506 binding protein 14
chr16_+_37884098	4.302		Lrrc58	leucine rich repeat containing 58
chr5_+_143734622	4.301
chr1_-_141982814	4.279		Cfh	complement component factor h

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.60	2.99e-09	GO:0065008	regulation of biological quality
2.07	1.04e-08	GO:0007155	cell adhesion
2.05	1.72e-08	GO:0022610	biological adhesion
1.92	3.04e-08	GO:0055114	oxidation-reduction process
1.33	4.68e-05	GO:0051179	localization
1.80	1.38e-04	GO:0006082	organic acid metabolic process
1.35	1.50e-04	GO:0051234	establishment of localization
1.35	1.62e-04	GO:0006810	transport
1.37	3.35e-04	GO:0048731	system development
1.36	3.37e-04	GO:0048522	positive regulation of cellular process
1.78	3.95e-04	GO:0019752	carboxylic acid metabolic process
1.78	3.95e-04	GO:0043436	oxoacid metabolic process
1.33	4.56e-04	GO:0048518	positive regulation of biological process
1.76	6.36e-04	GO:0042180	cellular ketone metabolic process
2.63	9.54e-04	GO:0042060	wound healing
1.29	1.07e-03	GO:0032502	developmental process
1.32	1.46e-03	GO:0048856	anatomical structure development
1.45	1.73e-03	GO:0051239	regulation of multicellular organismal process
2.46	2.22e-03	GO:0043062	extracellular structure organization
1.30	2.26e-03	GO:0007275	multicellular organismal development
1.93	2.64e-03	GO:0009611	response to wounding
1.60	2.97e-03	GO:2000026	regulation of multicellular organismal development
1.34	3.52e-03	GO:0048519	negative regulation of biological process
2.03	4.36e-03	GO:0032787	monocarboxylic acid metabolic process
1.34	8.25e-03	GO:0048523	negative regulation of cellular process
1.36	9.73e-03	GO:0030154	cell differentiation
1.35	1.02e-02	GO:0048869	cellular developmental process
1.39	1.34e-02	GO:0006950	response to stress
1.37	1.41e-02	GO:0042221	response to chemical stimulus
2.62	1.91e-02	GO:0030198	extracellular matrix organization
1.38	2.37e-02	GO:0044281	small molecule metabolic process
1.49	2.39e-02	GO:0032879	regulation of localization
1.55	2.58e-02	GO:0022008	neurogenesis
1.49	2.89e-02	GO:0050793	regulation of developmental process
1.71	3.14e-02	GO:0072358	cardiovascular system development
1.71	3.14e-02	GO:0072359	circulatory system development
1.91	3.19e-02	GO:0001944	vasculature development
1.52	3.91e-02	GO:0042592	homeostatic process
1.90	4.49e-02	GO:0046903	secretion
1.55	4.75e-02	GO:0045595	regulation of cell differentiation
1.56	4.78e-02	GO:0048699	generation of neurons

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.80	4.24e-18	GO:0005576	extracellular region
2.07	9.35e-16	GO:0044421	extracellular region part
1.27	2.00e-15	GO:0005737	cytoplasm
1.36	2.36e-15	GO:0044444	cytoplasmic part
1.90	2.52e-14	GO:0000267	cell fraction
2.16	1.47e-13	GO:0005615	extracellular space
1.99	4.85e-13	GO:0005626	insoluble fraction
2.01	7.31e-13	GO:0005624	membrane fraction
1.35	1.45e-08	GO:0071944	cell periphery
2.48	7.14e-08	GO:0005578	proteinaceous extracellular matrix
1.33	4.87e-07	GO:0005886	plasma membrane
2.26	1.41e-06	GO:0031012	extracellular matrix
3.12	1.02e-05	GO:0044420	extracellular matrix part
1.60	1.04e-05	GO:0042995	cell projection
2.15	2.11e-05	GO:0043025	neuronal cell body
1.43	3.42e-05	GO:0044459	plasma membrane part
2.08	4.66e-05	GO:0044297	cell body
2.12	5.48e-05	GO:0042598	vesicular fraction
2.14	5.75e-05	GO:0005792	microsome
1.12	1.05e-04	GO:0044424	intracellular part
1.85	1.71e-04	GO:0045202	synapse
1.11	2.89e-04	GO:0005622	intracellular
1.53	6.08e-04	GO:0005783	endoplasmic reticulum
1.72	8.51e-04	GO:0043005	neuron projection
1.14	1.25e-03	GO:0016020	membrane
1.46	1.60e-03	GO:0031090	organelle membrane
8.01	2.02e-03	GO:0060076	excitatory synapse
2.02	2.02e-03	GO:0005773	vacuole
1.63	4.45e-03	GO:0030054	cell junction
2.38	5.66e-03	GO:0005938	cell cortex
4.84	6.54e-03	GO:0005581	collagen
2.01	6.79e-03	GO:0045177	apical part of cell
1.53	9.44e-03	GO:0012505	endomembrane system
1.47	1.36e-02	GO:0005794	Golgi apparatus
1.11	1.52e-02	GO:0043226	organelle
1.81	1.73e-02	GO:0044456	synapse part
1.11	1.89e-02	GO:0043229	intracellular organelle
2.31	2.63e-02	GO:0019717	synaptosome
2.07	3.28e-02	GO:0016324	apical plasma membrane
2.70	3.60e-02	GO:0030427	site of polarized growth
1.69	3.71e-02	GO:0044463	cell projection part

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.32	1.17e-12	GO:0005515	protein binding
1.16	6.82e-09	GO:0005488	binding
1.90	7.59e-08	GO:0016491	oxidoreductase activity
1.95	4.37e-04	GO:0030246	carbohydrate binding
2.59	1.66e-03	GO:0005539	glycosaminoglycan binding
2.63	1.79e-03	GO:0004497	monooxygenase activity
1.56	2.80e-03	GO:0019899	enzyme binding
1.88	3.76e-03	GO:0032403	protein complex binding
2.76	4.32e-03	GO:0019838	growth factor binding
2.40	5.38e-03	GO:0001871	pattern binding
2.40	5.38e-03	GO:0030247	polysaccharide binding
1.18	7.18e-03	GO:0003824	catalytic activity
7.34	7.20e-03	GO:0005161	platelet-derived growth factor receptor binding
2.71	8.84e-03	GO:0008201	heparin binding
1.50	9.08e-03	GO:XXXXXXX	unannotated
2.29	1.32e-02	GO:0004866	endopeptidase inhibitor activity
2.21	2.69e-02	GO:0061135	endopeptidase regulator activity
1.45	2.73e-02	GO:0005102	receptor binding
1.64	3.15e-02	GO:0008092	cytoskeletal protein binding
2.17	3.78e-02	GO:0030414	peptidase inhibitor activity
1.63	4.21e-02	GO:0005509	calcium ion binding
4.19	4.40e-02	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
2.52	4.49e-02	GO:0004867	serine-type endopeptidase inhibitor activity
3.59	4.67e-02	GO:0043498	cell surface binding
2.05	4.92e-02	GO:0061134	peptidase regulator activity