Motif ID: HMX1.p2

Z-value: 1.296


Transcription factors associated with HMX1.p2:

Gene SymbolEntrez IDGene Name
Hmx1 15371 H6 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx1chr5_+_35731765-0.223.2e-03Click!


Activity profile for motif HMX1.p2.

activity profile for motif HMX1.p2


Sorted Z-values histogram for motif HMX1.p2

Sorted Z-values for motif HMX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_11586215 27.125 NM_001025597
NM_009578
Ikzf1

IKAROS family zinc finger 1

chr8_+_90796301 18.002 NM_007406
Adcy7
adenylate cyclase 7
chrX_-_7248403 17.506 NM_019755
Plp2
proteolipid protein 2
chr11_+_68245608 17.471 NM_177320
Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5, p101
chr6_-_91066773 14.250 Nup210
nucleoporin 210
chr6_-_91066809 14.149 NM_018815
Nup210
nucleoporin 210
chr3_-_54538938 13.021 Exosc8
exosome component 8
chr17_+_35331446 12.979 NM_008518
Ltb
lymphotoxin B
chr17_-_36282006 11.985 H2-D1
histocompatibility 2, D region locus 1
chr11_+_3190334 11.246 NM_019574
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr1_+_52065469 11.159 Stat4
signal transducer and activator of transcription 4
chr6_-_124683046 10.917 NM_013545
Ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr2_+_152934184 10.829 NM_001172117
NM_010407
Hck

hemopoietic cell kinase

chr15_-_78403110 10.499 NM_009008
Rac2
RAS-related C3 botulinum substrate 2
chr11_-_117687109 10.306 NM_009387
Tk1
thymidine kinase 1
chr5_+_123844794 10.097 NM_133917
NM_177582
Mlxip

MLX interacting protein

chr15_-_102062331 9.934 NM_013566
Itgb7
integrin beta 7
chr7_-_56136405 9.840 NM_001013368
E2f8
E2F transcription factor 8
chr7_-_90883999 9.680 NM_010551
Il16
interleukin 16
chr1_+_52065087 9.499 NM_011487
Stat4
signal transducer and activator of transcription 4
chr2_-_73291933 9.345 Wipf1
WAS/WASL interacting protein family, member 1
chr11_+_11586273 9.339 Ikzf1
IKAROS family zinc finger 1
chr15_-_102062309 9.337 Itgb7
integrin beta 7
chr10_-_6373309 9.194 Mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr10_+_79451332 8.664 NM_007725
Cnn2
calponin 2
chr10_-_6373388 8.614 NM_001170785
NM_001170786
NM_172308
Mthfd1l


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr3_+_60305108 8.460 NM_020007
Mbnl1
muscleblind-like 1 (Drosophila)
chr11_-_102180282 8.456 Ubtf
upstream binding transcription factor, RNA polymerase I
chrX_+_48194578 8.300 NM_133729
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr17_+_35400983 8.180 H2-D1
histocompatibility 2, D region locus 1
chr19_-_3897078 8.075 Tcirg1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr11_-_102180258 8.027 Ubtf
upstream binding transcription factor, RNA polymerase I
chrX_+_48194531 7.895 2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr9_-_110556645 7.892 NM_183276
Nbeal2
neurobeachin-like 2
chr5_-_135090819 7.880 NM_020044
NM_022964
Lat2

linker for activation of T cells family, member 2

chr11_+_70246079 7.710 NM_145429
Arrb2
arrestin, beta 2
chr8_-_107784507 7.682 Tradd
TNFRSF1A-associated via death domain
chr3_-_135988955 7.547 NM_001033350
Bank1
B-cell scaffold protein with ankyrin repeats 1
chr11_-_102180374 7.495 NM_011551
Ubtf
upstream binding transcription factor, RNA polymerase I
chr7_+_138712015 7.483 Bub3
budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
chr16_-_32165509 7.452 NM_146069
Lrrc33
leucine rich repeat containing 33
chrX_+_48194918 7.328 2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr7_-_56136367 7.271 E2f8
E2F transcription factor 8
chr5_-_98459488 7.104 Antxr2
anthrax toxin receptor 2
chr1_-_183772442 7.023 NM_133815
Lbr
lamin B receptor
chr1_+_140860285 6.898 NM_001166501
Dennd1b
DENN/MADD domain containing 1B
chr9_+_108462759 6.873 NM_011830
Impdh2
inosine 5'-phosphate dehydrogenase 2
chr16_-_55838747 6.812 NM_001159395
NM_030612
Nfkbiz

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

chr7_+_19469999 6.756 NM_009402
Pglyrp1
peptidoglycan recognition protein 1
chr17_-_71660199 6.750 NM_145158
Emilin2
elastin microfibril interfacer 2
chr16_-_55838834 6.643 Nfkbiz
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr1_-_167124442 6.456 NM_145512
Sft2d2
SFT2 domain containing 2
chrX_-_71491736 6.441 Flna
filamin, alpha
chr18_+_67448839 6.361 NM_053261
Impa2
inositol (myo)-1(or 4)-monophosphatase 2
chr16_-_92605804 6.265 Runx1
runt related transcription factor 1
chr19_-_41459518 6.233 NM_031376
Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr7_+_89003886 6.230 NM_145375
Tm6sf1
transmembrane 6 superfamily member 1
chr9_+_106109125 6.220 Twf2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chrX_-_71491851 6.211 NM_010227
Flna
filamin, alpha
chr12_+_33987379 6.179 NM_001033436
Atxn7l1
ataxin 7-like 1
chr2_+_125073393 6.061 Dut
deoxyuridine triphosphatase
chr17_+_35576081 5.957 NM_001198560
NM_001198561
NM_010394
H2-Q9
H2-Q7


histocompatibility 2, Q region locus 9
histocompatibility 2, Q region locus 7


chr6_+_83293025 5.909 Mobkl1b
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr2_+_103810274 5.892 NM_001142335
NM_008505
Lmo2

LIM domain only 2

chr4_-_133443662 5.791 NM_009097
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr9_-_114690887 5.734 NM_133978
Cmtm7
CKLF-like MARVEL transmembrane domain containing 7
chr10_+_43198945 5.732 NM_199028
Bend3
BEN domain containing 3
chr7_+_20162604 5.702 NM_022409
Zfp296
zinc finger protein 296
chrX_+_155693729 5.646 Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr3_-_54539285 5.645 NM_001163570
NM_027148
Exosc8

exosome component 8

chr11_-_72951771 5.643 NM_010353
Gsg2
germ cell-specific gene 2
chr6_+_70557402 5.597


chr17_+_57418517 5.538 NM_001163815
NM_001163816
NM_011691
Vav1


vav 1 oncogene


chrX_-_71618617 5.475 Slc10a3
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
chr18_-_36886051 5.399 Cd14
CD14 antigen
chr12_+_82049290 5.391 Srsf5
serine/arginine-rich splicing factor 5
chr19_-_7315495 5.370 NM_027643
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr17_-_34136793 5.315 H2-K1
histocompatibility 2, K1, K region
chr6_+_17015159 5.311 Tes
testis derived transcript
chr14_-_56721304 5.275 NM_007800
Ctsg
cathepsin G
chr10_+_59809598 5.252 NM_001159572
NM_028732
4632428N05Rik

RIKEN cDNA 4632428N05 gene

chr9_+_32503600 5.217 NM_001038642
NM_011808
Ets1

E26 avian leukemia oncogene 1, 5' domain

chr8_+_86479405 5.214 NM_024184
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr17_-_34136726 5.187 H2-K1
histocompatibility 2, K1, K region
chr16_+_57549340 5.179 NM_001177871
Filip1l
filamin A interacting protein 1-like
chr8_+_77633426 5.175 NM_008566
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr17_+_35137995 5.155 Vars
valyl-tRNA synthetase
chr1_-_39634096 5.119 NM_001033135
Rnf149
ring finger protein 149
chr2_+_153475189 5.113 NM_001003960
NM_001003961
NM_001003963
NM_001122997
NM_010068
Dnmt3b




DNA methyltransferase 3B




chr7_-_25873560 5.007


chr7_-_148286422 4.984 NM_023059
Sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr15_+_81416643 4.965 NM_177821
Ep300
E1A binding protein p300
chr5_+_30339682 4.951 NM_031168
Il6
interleukin 6
chr11_-_114995194 4.907 NM_001169153
NM_145634
Cd300lf

CD300 antigen like family member F

chr5_+_72594551 4.885 NM_153389
Atp10d
ATPase, class V, type 10D
chr6_+_38868942 4.878 NM_011539
Tbxas1
thromboxane A synthase 1, platelet
chr12_+_8797502 4.821


chr6_-_127100954 4.815 NM_009829
Ccnd2
cyclin D2
chr3_-_97414085 4.729 NM_026539
Chd1l
chromodomain helicase DNA binding protein 1-like
chrX_+_20002809 4.707 Phf16
PHD finger protein 16
chrX_-_71269083 4.706 Irak1
interleukin-1 receptor-associated kinase 1
chr1_+_58852303 4.672 Casp8
caspase 8
chr4_-_94223435 4.611 NM_026368
5830433M19Rik
RIKEN cDNA 5830433M19 gene
chr7_+_86059126 4.586 Isg20
interferon-stimulated protein
chr19_+_7049639 4.564 Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_+_57244807 4.548 NM_009404
Tnfsf9
tumor necrosis factor (ligand) superfamily, member 9
chr1_+_58852471 4.512 Casp8
caspase 8
chr1_+_182571464 4.498 NM_001103182
NM_175186
Lin9

lin-9 homolog (C. elegans)

chr1_+_154613763 4.495 Arpc5
actin related protein 2/3 complex, subunit 5
chr7_-_26004870 4.492 NM_207677
Dedd2
death effector domain-containing DNA binding protein 2
chr5_-_123438517 4.492 NM_001005866
Kdm2b
lysine (K)-specific demethylase 2B
chr6_-_126889539 4.488 NM_009013
Rad51ap1
RAD51 associated protein 1
chrX_-_71618556 4.480 NM_145406
Slc10a3-ubl4
Slc10a3
Slc10a3-Ubl4 readthrough transcript
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
chr9_+_44789868 4.480 NM_013487
Cd3d
CD3 antigen, delta polypeptide
chr8_-_97437166 4.460 Ccdc102a
coiled-coil domain containing 102A
chr3_-_89222140 4.457 NM_016904
Cks1b
CDC28 protein kinase 1b
chr1_-_183141500 4.455 Wdr26
WD repeat domain 26
chr5_-_139936486 4.454 NM_028469
3110082I17Rik
RIKEN cDNA 3110082I17 gene
chr6_-_116411041 4.401 NM_009662
Alox5
arachidonate 5-lipoxygenase
chr6_+_113647848 4.398 Tatdn2
TatD DNase domain containing 2
chr7_-_7074155 4.396 NM_172738
Zfp954
zinc finger protein 954
chrX_+_159339561 4.369 Ctps2
cytidine 5'-triphosphate synthase 2
chr1_+_61034757 4.366 NM_017480
Icos
inducible T-cell co-stimulator
chr14_-_47809063 4.342 NM_008102
Gch1
GTP cyclohydrolase 1
chr1_+_59969845 4.331 NM_001037725
Fam117b
family with sequence similarity 117, member B
chr16_-_92697567 4.316 NM_001111023
NM_009821
Runx1

runt related transcription factor 1

chr1_+_58852217 4.309 NM_009812
Casp8
caspase 8
chr4_+_135750500 4.272 E2f2
E2F transcription factor 2
chr6_-_28211600 4.271 NM_001081678
Zfp800
zinc finger protein 800
chr2_+_130100145 4.230 NM_024193
Nop56
NOP56 ribonucleoprotein homolog (yeast)
chr19_+_36484237 4.220 Pcgf5
polycomb group ring finger 5
chr5_+_28492235 4.176 NM_010134
En2
engrailed 2
chr4_-_133684599 4.164 NM_080559
Sh3bgrl3
SH3 domain binding glutamic acid-rich protein-like 3
chr17_-_23810808 4.148 Thoc6
THO complex 6 homolog (Drosophila)
chr2_+_118938549 4.147 NM_011234
Rad51
RAD51 homolog (S. cerevisiae)
chr17_+_35516558 4.146 NM_001143689
H2-Gs10
MHC class I like protein GS10
chr16_+_17619441 4.146 NM_001164609
NM_001164610
NM_001164611
NM_029945
Smpd4



sphingomyelin phosphodiesterase 4



chr7_+_26412621 4.143 NM_001036740
NM_146184
B3gnt8

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

chr1_+_132762248 4.138 Faim3
Fas apoptotic inhibitory molecule 3
chr5_-_100465086 4.126 Hnrpdl
heterogeneous nuclear ribonucleoprotein D-like
chr8_+_108583449 4.104 NM_010901
Nfatc3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr10_-_115922360 4.072 Cnot2
CCR4-NOT transcription complex, subunit 2
chr2_-_169968174 4.040 NM_001159683
Zfp217
zinc finger protein 217
chr7_+_87377748 4.023 NM_178752
D330012F22Rik
RIKEN cDNA D330012F22 gene
chr3_-_94946256 4.017 NM_027206
Tnfaip8l2
tumor necrosis factor, alpha-induced protein 8-like 2
chr9_-_57492978 4.014 NM_007783
Csk
c-src tyrosine kinase
chrX_+_140752508 3.981 NM_026247
Alg13
asparagine-linked glycosylation 13 homolog (S. cerevisiae)
chr17_+_57244828 3.974 Tnfsf9
tumor necrosis factor (ligand) superfamily, member 9
chr9_-_20781206 3.954 NM_010333
S1pr2
sphingosine-1-phosphate receptor 2
chr13_+_55471165 3.931 Rgs14
regulator of G-protein signaling 14
chr17_-_23810736 3.921 NM_001008425
Thoc6
THO complex 6 homolog (Drosophila)
chr5_-_139936448 3.917 3110082I17Rik
RIKEN cDNA 3110082I17 gene
chr14_+_26661614 3.902 NM_013469
Anxa11
annexin A11
chr11_+_77796215 3.892 NM_174852
Phf12
PHD finger protein 12
chr19_-_5272972 3.890 NM_153129
Pacs1
phosphofurin acidic cluster sorting protein 1
chr15_-_9459612 3.882 NM_008372
Il7r
interleukin 7 receptor
chr12_+_4599810 3.874 NM_001198968
NM_001198969
NM_011365
Itsn2


intersectin 2


chr2_+_125073450 3.846 Dut
deoxyuridine triphosphatase
chr18_+_56867378 3.837 NM_010721
Lmnb1
lamin B1
chrX_+_97821403 3.827 NM_008446
Kif4
kinesin family member 4
chr5_-_111082269 3.820 Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)
chr9_-_20781133 3.802 S1pr2
sphingosine-1-phosphate receptor 2
chr8_-_116372376 3.801 Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr2_-_162486634 3.801 Ptprt
protein tyrosine phosphatase, receptor type, T
chr13_+_20182408 3.755 Elmo1
engulfment and cell motility 1, ced-12 homolog (C. elegans)
chr1_-_145549903 3.747 Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr8_+_97541591 3.742 NM_173036
Gpr97
G protein-coupled receptor 97
chr4_-_11313886 3.715 NM_194055
Esrp1
epithelial splicing regulatory protein 1
chr2_-_26997842 3.713 Fam163b
family with sequence similarity 163, member B
chr1_-_54983048 3.709 Ankrd44
ankyrin repeat domain 44
chr14_+_57194455 3.707 NM_001145978
Parp4
poly (ADP-ribose) polymerase family, member 4
chr4_+_140542775 3.702 NM_001164366
NM_029097
Atp13a2

ATPase type 13A2

chr17_+_35137851 3.700 NM_011690
Vars
valyl-tRNA synthetase
chr19_+_4097894 3.691 Cdk2ap2
CDK2-associated protein 2
chr19_+_39005433 3.676 NM_008234
Hells
helicase, lymphoid specific
chr1_+_59970358 3.667 Fam117b
family with sequence similarity 117, member B
chr7_-_85992096 3.610 NM_029585
Det1
de-etiolated homolog 1 (Arabidopsis)
chrX_+_156411885 3.606 Sh3kbp1
SH3-domain kinase binding protein 1
chr1_-_145549758 3.606 NM_145991
Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr12_+_119082333 3.593 NM_146040
Cdca7l
cell division cycle associated 7 like
chr2_+_129024496 3.583 NM_001159593
NM_015747
Slc20a1

solute carrier family 20, member 1

chr13_-_32430412 3.575 NM_146041
Gmds
GDP-mannose 4, 6-dehydratase
chr4_-_19497166 3.571 NM_027769
Cpne3
copine III
chr1_-_54983211 3.570 NM_001081433
Ankrd44
ankyrin repeat domain 44
chr19_-_60656627 3.564 NM_001172096
NM_001172097
NM_030197
2700078E11Rik


RIKEN cDNA 2700078E11 gene


chr19_+_8810274 3.558 NM_134139
Wdr74
WD repeat domain 74
chr4_-_123427465 3.554 NM_023423
Akirin1
akirin 1
chr13_-_51889012 3.534 NM_013660
Sema4d
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr4_-_34830178 3.533 NM_013889
Zfp292
zinc finger protein 292
chr7_+_56044379 3.521 Zdhhc13
zinc finger, DHHC domain containing 13
chrX_+_104451216 3.519 NM_001177781
NM_001033251
Gpr174

G protein-coupled receptor 174

chr19_+_46130978 3.491 NM_001081214
Pprc1
peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr10_+_79451369 3.472 Cnn2
calponin 2
chr6_+_42214999 3.456 NM_007610
Casp2
caspase 2
chr2_-_60590923 3.454 Rbms1
RNA binding motif, single stranded interacting protein 1
chrX_+_20002875 3.446 Phf16
PHD finger protein 16
chr6_+_83293435 3.433 Mobkl1b
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr5_+_65194814 3.430 Klf3
Kruppel-like factor 3 (basic)
chr2_-_51828671 3.430 NM_001141948
NM_001141949
NM_019401
Nmi


N-myc (and STAT) interactor


chrX_+_156065141 3.402 NM_001135727
Sh3kbp1
SH3-domain kinase binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.72 9.57e-24 GO:0010468 regulation of gene expression
1.59 2.48e-23 GO:0031323 regulation of cellular metabolic process
1.60 5.70e-23 GO:0060255 regulation of macromolecule metabolic process
1.49 1.07e-22 GO:0044260 cellular macromolecule metabolic process
1.58 9.56e-22 GO:0080090 regulation of primary metabolic process
1.74 9.61e-22 GO:0051252 regulation of RNA metabolic process
1.52 1.79e-21 GO:0019222 regulation of metabolic process
1.44 1.80e-21 GO:0043170 macromolecule metabolic process
1.66 1.83e-20 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.65 3.14e-20 GO:0051171 regulation of nitrogen compound metabolic process
1.72 4.56e-20 GO:0006355 regulation of transcription, DNA-dependent
1.68 6.61e-20 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.67 7.89e-20 GO:0010556 regulation of macromolecule biosynthetic process
1.65 1.18e-19 GO:0031326 regulation of cellular biosynthetic process
1.63 2.99e-19 GO:0009889 regulation of biosynthetic process
1.56 2.98e-18 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 3.51e-18 GO:0044238 primary metabolic process
1.64 4.91e-18 GO:0010467 gene expression
1.65 1.27e-16 GO:0016070 RNA metabolic process
1.49 1.90e-16 GO:0006807 nitrogen compound metabolic process
1.64 2.26e-16 GO:0009059 macromolecule biosynthetic process
1.33 6.72e-16 GO:0044237 cellular metabolic process
1.49 7.10e-16 GO:0034641 cellular nitrogen compound metabolic process
1.63 8.43e-16 GO:0034645 cellular macromolecule biosynthetic process
1.53 1.61e-15 GO:0009058 biosynthetic process
1.53 2.01e-15 GO:0044249 cellular biosynthetic process
1.57 7.26e-15 GO:0090304 nucleic acid metabolic process
1.28 1.04e-14 GO:0008152 metabolic process
1.52 1.59e-12 GO:0048518 positive regulation of biological process
1.68 2.50e-12 GO:0006351 transcription, DNA-dependent
1.67 3.08e-12 GO:0032774 RNA biosynthetic process
1.53 1.32e-11 GO:0048522 positive regulation of cellular process
1.47 3.90e-11 GO:0007275 multicellular organismal development
1.43 2.85e-10 GO:0032502 developmental process
1.62 3.21e-10 GO:0048513 organ development
1.49 3.37e-09 GO:0048731 system development
1.55 4.95e-09 GO:0030154 cell differentiation
1.54 7.17e-09 GO:0048869 cellular developmental process
1.68 1.71e-08 GO:0010604 positive regulation of macromolecule metabolic process
1.65 1.75e-08 GO:0009893 positive regulation of metabolic process
1.44 2.26e-08 GO:0048856 anatomical structure development
1.67 2.28e-08 GO:0031325 positive regulation of cellular metabolic process
1.85 4.90e-08 GO:0010628 positive regulation of gene expression
1.46 9.89e-08 GO:0048519 negative regulation of biological process
1.81 1.59e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.85 3.51e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.78 4.09e-07 GO:0051173 positive regulation of nitrogen compound metabolic process
1.84 4.21e-07 GO:0051254 positive regulation of RNA metabolic process
1.72 1.27e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.72 1.50e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.75 1.63e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.70 2.80e-06 GO:0009891 positive regulation of biosynthetic process
1.44 4.23e-06 GO:0048523 negative regulation of cellular process
1.68 5.60e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.72 8.43e-06 GO:0009888 tissue development
1.72 9.87e-06 GO:2000026 regulation of multicellular organismal development
1.64 1.18e-05 GO:0009892 negative regulation of metabolic process
1.12 1.29e-05 GO:0009987 cellular process
2.05 1.36e-05 GO:0048598 embryonic morphogenesis
1.87 3.35e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.67 3.95e-05 GO:0002376 immune system process
1.64 5.11e-05 GO:0031324 negative regulation of cellular metabolic process
1.33 8.95e-05 GO:0071840 cellular component organization or biogenesis
1.60 1.60e-04 GO:0050793 regulation of developmental process
1.17 1.81e-04 GO:0050794 regulation of cellular process
1.15 1.93e-04 GO:0065007 biological regulation
1.16 2.06e-04 GO:0050789 regulation of biological process
2.36 4.10e-04 GO:0046649 lymphocyte activation
2.14 5.32e-04 GO:0030097 hemopoiesis
1.58 5.40e-04 GO:0043067 regulation of programmed cell death
1.67 5.48e-04 GO:0045595 regulation of cell differentiation
2.20 6.78e-04 GO:0003002 regionalization
1.76 7.10e-04 GO:0002682 regulation of immune system process
1.31 7.62e-04 GO:0016043 cellular component organization
1.45 9.80e-04 GO:0051239 regulation of multicellular organismal process
1.94 1.01e-03 GO:0002684 positive regulation of immune system process
1.94 1.01e-03 GO:0045597 positive regulation of cell differentiation
2.16 1.08e-03 GO:0045321 leukocyte activation
1.51 1.23e-03 GO:0007399 nervous system development
1.55 1.29e-03 GO:0010941 regulation of cell death
1.35 1.61e-03 GO:0044267 cellular protein metabolic process
2.04 2.15e-03 GO:0001775 cell activation
1.68 2.20e-03 GO:0010629 negative regulation of gene expression
1.83 2.35e-03 GO:0043069 negative regulation of programmed cell death
1.55 2.60e-03 GO:0042981 regulation of apoptosis
1.81 2.60e-03 GO:0060548 negative regulation of cell death
1.42 2.67e-03 GO:0048583 regulation of response to stimulus
1.93 2.84e-03 GO:0007389 pattern specification process
1.97 3.16e-03 GO:0007420 brain development
2.46 3.30e-03 GO:0002521 leukocyte differentiation
1.65 3.89e-03 GO:0016265 death
1.45 3.98e-03 GO:0009653 anatomical structure morphogenesis
1.94 4.39e-03 GO:0002520 immune system development
1.97 4.41e-03 GO:0048534 hemopoietic or lymphoid organ development
1.65 4.54e-03 GO:0008219 cell death
1.55 5.55e-03 GO:0042127 regulation of cell proliferation
1.75 5.60e-03 GO:0008284 positive regulation of cell proliferation
1.47 6.33e-03 GO:0009966 regulation of signal transduction
1.67 8.07e-03 GO:0051253 negative regulation of RNA metabolic process
1.59 1.02e-02 GO:0048699 generation of neurons
5.48 1.14e-02 GO:0045646 regulation of erythrocyte differentiation
1.29 1.15e-02 GO:0019538 protein metabolic process
1.77 1.22e-02 GO:0043066 negative regulation of apoptosis
1.71 1.35e-02 GO:0051094 positive regulation of developmental process
1.66 1.52e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.99 1.58e-02 GO:0048568 embryonic organ development
1.64 1.69e-02 GO:0009887 organ morphogenesis
1.81 1.76e-02 GO:0060429 epithelium development
1.64 1.76e-02 GO:0012501 programmed cell death
1.55 1.85e-02 GO:0022008 neurogenesis
1.87 1.89e-02 GO:0016071 mRNA metabolic process
2.47 1.96e-02 GO:0042110 T cell activation
1.31 2.18e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.58 2.52e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.54 2.53e-02 GO:0009790 embryo development
1.40 2.62e-02 GO:0006996 organelle organization
1.63 2.88e-02 GO:0006915 apoptosis
1.35 3.00e-02 GO:0043412 macromolecule modification
1.59 3.06e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 3.14e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.55 3.30e-02 GO:0044093 positive regulation of molecular function

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.48 1.67e-25 GO:0005634 nucleus
1.26 2.03e-20 GO:0043226 organelle
1.23 2.11e-20 GO:0044424 intracellular part
1.22 2.45e-20 GO:0005622 intracellular
1.26 5.25e-20 GO:0043229 intracellular organelle
1.27 4.37e-18 GO:0043227 membrane-bounded organelle
1.27 9.48e-18 GO:0043231 intracellular membrane-bounded organelle
1.62 2.41e-11 GO:0044428 nuclear part
1.62 4.68e-09 GO:0031981 nuclear lumen
1.55 2.46e-08 GO:0070013 intracellular organelle lumen
1.55 2.91e-08 GO:0043233 organelle lumen
1.31 3.30e-08 GO:0044422 organelle part
1.09 4.44e-08 GO:0005623 cell
1.09 4.44e-08 GO:0044464 cell part
1.31 4.93e-08 GO:0044446 intracellular organelle part
1.52 1.03e-07 GO:0031974 membrane-enclosed lumen
1.62 7.05e-06 GO:0005654 nucleoplasm
1.17 8.18e-06 GO:0005737 cytoplasm
1.29 7.81e-05 GO:0032991 macromolecular complex
1.65 6.81e-04 GO:0044451 nucleoplasm part
1.31 9.47e-04 GO:0043228 non-membrane-bounded organelle
1.31 9.47e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.41 1.03e-03 GO:0005829 cytosol
1.27 2.23e-03 GO:0043234 protein complex
1.78 9.09e-03 GO:0005730 nucleolus
1.86 9.94e-03 GO:0005667 transcription factor complex
1.20 4.12e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.23 5.39e-22 GO:0005488 binding
1.62 7.00e-18 GO:0003676 nucleic acid binding
1.33 1.19e-13 GO:0005515 protein binding
1.63 1.39e-11 GO:0003677 DNA binding
1.81 6.21e-09 GO:0030528 transcription regulator activity
1.91 1.47e-07 GO:0043565 sequence-specific DNA binding
1.83 7.40e-07 GO:0003723 RNA binding
1.78 1.53e-06 GO:0001071 nucleic acid binding transcription factor activity
1.78 1.53e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.38 8.35e-05 GO:0000166 nucleotide binding
2.02 6.13e-03 GO:0019901 protein kinase binding
1.65 7.80e-03 GO:0004672 protein kinase activity
1.58 9.69e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.34 1.05e-02 GO:0016740 transferase activity
1.51 1.76e-02 GO:0016301 kinase activity
1.85 2.37e-02 GO:0019900 kinase binding
1.71 3.23e-02 GO:0004674 protein serine/threonine kinase activity
1.44 4.43e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups