• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: IKZF1.p2

Z-value: 1.588

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_+_56040193	32.391		Gpm6a	glycoprotein m6a
chr8_+_56040211	31.644		Gpm6a	glycoprotein m6a
chr7_+_120909625	29.460		Spon1	spondin 1, (f-spondin) extracellular matrix protein
chr8_+_56040080	28.521	NM_153581	Gpm6a	glycoprotein m6a
chr15_+_91881593	28.404	NM_001159648	Cntn1	contactin 1
chr7_+_31092787	24.320		Clip3	CAP-GLY domain containing linker protein 3
chr8_+_56040445	21.809		Gpm6a	glycoprotein m6a
chr8_+_56040553	21.260		Gpm6a	glycoprotein m6a
chr4_-_151235861	21.072	NM_001081557 NM_001195565	Camta1	calmodulin binding transcription activator 1
chr7_-_82454147	20.442	NM_153579	Sv2b	synaptic vesicle glycoprotein 2 b
chr14_-_71035662	20.230		Epb4.9	erythrocyte protein band 4.9
chr13_+_54472806	20.176		Cplx2	complexin 2
chr12_-_11443284	19.706	NM_012038	Vsnl1	visinin-like 1
chr8_-_67171805	18.671	NM_013494	Cpe	carboxypeptidase E
chr8_-_67171692	18.368		Cpe	carboxypeptidase E
chr7_-_112717810	17.950		Apbb1	amyloid beta (A4) precursor protein-binding, family B, member 1
chr14_-_119324535	17.839		Dzip1	DAZ interacting protein 1
chr16_+_91270319	17.334		Olig1	oligodendrocyte transcription factor 1
chr3_+_90346956	17.033		S100a16	S100 calcium binding protein A16
chr1_-_79436564	16.935	NM_009129	Scg2	secretogranin II
chr14_+_28435613	16.903	NM_177814	Erc2	ELKS/RAB6-interacting/CAST family member 2
chr6_-_92484838	16.307	NM_001134459	Prickle2	prickle homolog 2 (Drosophila)
chr1_+_34356614	15.623		Dst	dystonin
chr12_+_110782654	15.104		Meg3	maternally expressed 3
chr16_-_28445276	14.336	NM_183064	Fgf12	fibroblast growth factor 12
chr7_-_20282950	14.193		Apoe	apolipoprotein E
chrX_-_100381973	14.190	NM_008671	Nap1l2	nucleosome assembly protein 1-like 2
chr16_-_20621287	14.141	NM_028420	Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2
chr9_-_53822931	13.416		Elmod1	ELMO domain containing 1
chr12_+_16660521	12.769		Ntsr2	neurotensin receptor 2
chr4_-_25727109	12.708	NM_010243	Fut9	fucosyltransferase 9
chr9_-_53823107	12.583	NM_177769	Elmod1	ELMO domain containing 1
chr2_-_104250490	12.480	NM_001033347	D430041D05Rik	RIKEN cDNA D430041D05 gene
chr2_-_170232008	11.785		Bcas1	breast carcinoma amplified sequence 1
chr7_+_80885175	11.780	NM_001162532	Fam174b	family with sequence similarity 174, member B
chr7_+_120909509	11.639	NM_145584	Spon1	spondin 1, (f-spondin) extracellular matrix protein
chr2_-_25324650	11.029		Ptgds	prostaglandin D2 synthase (brain)
chr3_-_80606500	10.862		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr11_-_119878383	10.726		Aatk	apoptosis-associated tyrosine kinase
chr10_+_115738429	10.700	NM_029928	Ptprb	protein tyrosine phosphatase, receptor type, B
chr14_-_104242892	10.594	NM_007904	Ednrb	endothelin receptor type B
chr7_+_120909680	10.403		Spon1	spondin 1, (f-spondin) extracellular matrix protein
chr15_+_39491073	10.309		Rims2	regulating synaptic membrane exocytosis 2
chr7_+_80885223	10.253		Fam174b	family with sequence similarity 174, member B
chr2_-_165060352	10.139		Cdh22	cadherin 22
chr13_+_54472705	10.132	NM_009946	Cplx2	complexin 2
chr6_+_47194393	9.981	NM_025771	Cntnap2	contactin associated protein-like 2
chr1_-_84692750	9.976	NM_152915	Dner	delta/notch-like EGF-related receptor
chr1_-_134264461	9.976		Tmcc2	transmembrane and coiled-coil domains 2
chr6_+_88674821	9.880		Mgll	monoglyceride lipase
chr12_+_16660245	9.851	NM_008747	Ntsr2	neurotensin receptor 2
chr10_-_79600131	9.792	NM_001195268	Dos	downstream of Stk11
chr2_-_92241282	9.756		Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1
chr2_-_80421054	9.696	NM_016965	Nckap1	NCK-associated protein 1
chr6_+_88674398	9.674	NM_001166249 NM_011844	Mgll	monoglyceride lipase
chr4_+_122860705	9.583	NM_174998	Hpcal4	hippocalcin-like 4
chr4_+_84851330	9.566	NM_019535	Sh3gl2	SH3-domain GRB2-like 2
chr6_+_134932018	9.536	NM_001109914	Apold1	apolipoprotein L domain containing 1
chr16_+_38089086	9.388	NM_019827	Gsk3b	glycogen synthase kinase 3 beta
chr18_+_45428413	9.384		Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr19_+_47089168	9.338	NM_146100	Ina	internexin neuronal intermediate filament protein, alpha
chr8_-_48437701	9.278	NM_175162	Stox2	storkhead box 2
chr8_+_56122680	9.191		Gpm6a	glycoprotein m6a
chr2_-_148558110	9.156	NM_019632	Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta
chr13_-_19711409	9.110	NM_134065	Epdr1	ependymin related protein 1 (zebrafish)
chr2_+_158436493	8.997	NM_009508	Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1
chr2_+_157740281	8.957	NM_198627	Vstm2l	V-set and transmembrane domain containing 2-like
chr2_-_25325248	8.931	NM_008963	Ptgds	prostaglandin D2 synthase (brain)
chr8_+_11758376	8.774		Arhgef7	Rho guanine nucleotide exchange factor (GEF7)
chr3_-_31209216	8.733	NM_172861	Slc7a14	solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr2_-_92241357	8.682	NM_011162	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1
chr6_+_121586190	8.663	NM_175628	A2m	alpha-2-macroglobulin
chr11_-_86807216	8.549	NM_001005341	Ypel2	yippee-like 2 (Drosophila)
chr6_+_49772688	8.540	NM_023456	Npy	neuropeptide Y
chr7_-_30066910	8.436	NM_001082548 NM_011464	Spint2	serine protease inhibitor, Kunitz type 2
chr18_+_35020859	8.426	NM_007913	Egr1	early growth response 1
chr3_-_107320881	8.388	NM_172271	Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17
chr4_+_126287086	8.341	NM_001013755 NM_001145950	5730409E04Rik	RIKEN cDNA 5730409E04Rik gene
chrX_+_132673583	8.322	NM_212457	Bex4	brain expressed gene 4
chr1_+_10983542	8.272	NM_029525	Prex2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr16_+_41533317	8.255	NM_175548	Lsamp	limbic system-associated membrane protein
chr3_+_7366586	8.178	NM_008862	Pkia	protein kinase inhibitor, alpha
chr7_-_112781902	8.130	NM_018880	Trim3	tripartite motif-containing 3
chr16_-_45724720	8.068		Tagln3	transgelin 3
chr15_-_43002356	7.993	NM_172815	Rspo2	R-spondin 2 homolog (Xenopus laevis)
chr7_-_30066867	7.990		Spint2	serine protease inhibitor, Kunitz type 2
chr9_+_46721685	7.906		2900052N01Rik	RIKEN cDNA 2900052N01 gene
chr13_-_58009599	7.892		Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
chr6_+_91124214	7.863		Hdac11	histone deacetylase 11
chr10_-_42893894	7.720		Sobp	sine oculis-binding protein homolog (Drosophila)
chr10_-_108448003	7.712		Syt1	synaptotagmin I
chr2_-_17652669	7.634	NM_028757	Nebl	nebulette
chr9_-_121905086	7.591	NM_153540	C85492	expressed sequence C85492
chr2_-_25325196	7.566		Ptgds	prostaglandin D2 synthase (brain)
chr7_-_30066642	7.565		Spint2	serine protease inhibitor, Kunitz type 2
chr3_-_119486305	7.561	NM_019550	Ptbp2	polypyrimidine tract binding protein 2
chrX_-_100381703	7.561		Nap1l2	nucleosome assembly protein 1-like 2
chr9_-_59201234	7.411	NM_175325	Bbs4	Bardet-Biedl syndrome 4 (human)
chr12_+_70994091	7.359	NM_178628	Atl1	atlastin GTPase 1
chr14_-_7859962	7.353	NM_001164727	Gm10406	predicted gene 10406
chr1_-_170085798	7.335		Pbx1	pre B-cell leukemia transcription factor 1
chr4_-_147412872	7.281	NM_011929	Clcn6	chloride channel 6
chr12_+_75385267	7.274		1700086L19Rik	RIKEN cDNA 1700086L19 gene
chr8_-_112692071	7.248	NM_007586	Calb2	calbindin 2
chr1_-_42749940	7.231		2610017I09Rik	RIKEN cDNA 2610017I09 gene
chr10_-_108447996	7.217		Syt1	synaptotagmin I
chr8_-_127093601	7.126	NM_007428	Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr16_-_10447440	7.107	NM_001013778	Fam18a	family with sequence similarity 18, member A
chr18_+_38456315	7.094		Rnf14	ring finger protein 14
chr11_-_81781897	7.055	NM_001034013	Accn1	amiloride-sensitive cation channel 1, neuronal (degenerin)
chr9_-_50554613	7.011	NM_025865	2310030G06Rik	RIKEN cDNA 2310030G06 gene
chr5_-_21850490	6.963	NM_011261	Reln	reelin
chr18_+_63137573	6.941		Napg	N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr5_+_137994744	6.892	NM_031404	Actl6b	actin-like 6B
chr4_+_84851440	6.827		Sh3gl2	SH3-domain GRB2-like 2
chr19_-_5118229	6.789	NM_008451	Klc2	kinesin light chain 2
chr9_+_57810230	6.784		Sema7a	sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr17_-_67703726	6.743	NM_008984	Ptprm	protein tyrosine phosphatase, receptor type, M
chr16_+_91270009	6.703	NM_016968	Olig1	oligodendrocyte transcription factor 1
chr18_+_63137566	6.691	NM_028017	Napg	N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr3_+_152009483	6.662		Usp33	ubiquitin specific peptidase 33
chr2_-_155340538	6.655	NM_144786	Ggt7	gamma-glutamyltransferase 7
chr18_+_63137563	6.608		Napg	N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr16_-_34263047	6.582		Kalrn	kalirin, RhoGEF kinase
chr16_+_96689373	6.558		Pcp4	Purkinje cell protein 4
chr3_+_115711207	6.499	NM_001163514	Extl2	exostoses (multiple)-like 2
chr9_+_86465577	6.486	NM_001145969 NM_001145968 NM_027100	Rwdd2a	RWD domain containing 2A
chr3_-_119486136	6.470		Ptbp2	polypyrimidine tract binding protein 2
chr3_-_88964022	6.407		Hcn3	hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr18_-_75857207	6.394	NM_201354	Ctif	CBP80/20-dependent translation initiation factor
chr4_+_45985143	6.291		Tdrd7	tudor domain containing 7
chr1_-_75260687	6.290	NM_008985	Ptprn	protein tyrosine phosphatase, receptor type, N
chr14_+_58693951	6.255		Fgf9	fibroblast growth factor 9
chr18_+_35020867	6.241		Egr1	early growth response 1
chr18_+_63137605	6.228		Napg	N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr4_-_43591721	6.217	NM_172692	Gba2	glucosidase beta 2
chr17_-_25969789	6.192		Stub1	STIP1 homology and U-Box containing protein 1
chr14_+_119254123	6.188	NM_001160099 NM_021386	Cldn10	claudin 10
chr3_+_64913564	6.162	NM_010597	Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr3_-_80606704	6.130	NM_001039195 NM_001083806 NM_013540	Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr9_-_108474818	6.126		Dalrd3	DALR anticodon binding domain containing 3
chr12_+_118997623	6.118		Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5
chr9_-_114549148	6.115	NM_153585	Cnot10	CCR4-NOT transcription complex, subunit 10
chr6_+_54402876	6.046	NM_001167860 NM_001167861	Wipf3	WAS/WASL interacting protein family, member 3
chr4_+_115894518	6.037	NM_181585	Pik3r3	phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr18_+_63137550	6.006		Napg	N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr12_-_42212538	6.001		Lrrn3	leucine rich repeat protein 3, neuronal
chr16_-_34263272	5.994		Kalrn	kalirin, RhoGEF kinase
chr12_+_80130149	5.987	NM_181073	Plekhh1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr1_-_99992145	5.959	NM_013626	Pam	peptidylglycine alpha-amidating monooxygenase
chr10_+_127631656	5.874	NM_001033264	Gls2	glutaminase 2 (liver, mitochondrial)
chr11_+_94871181	5.833	NM_146025	Samd14	sterile alpha motif domain containing 14
chrX_+_5624820	5.825		Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr11_-_118216625	5.790		Timp2	tissue inhibitor of metalloproteinase 2
chr14_-_7937970	5.781	NM_001024712	Gm3696	predicted gene 3696
chr14_+_119254202	5.660		Cldn10	claudin 10
chr12_+_82732188	5.635	NM_001033149	Ttc9	tetratricopeptide repeat domain 9
chr9_+_99530246	5.559		Dzip1l	DAZ interacting protein 1-like
chr1_+_50984361	5.500	NM_019790	Tmeff2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr3_+_141128527	5.499	NM_009472	Unc5c	unc-5 homolog C (C. elegans)
chr3_-_88964115	5.497		Hcn3	hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chrX_-_119510890	5.497	NM_138742	Nap1l3	nucleosome assembly protein 1-like 3
chr2_-_113669229	5.389		Scg5	secretogranin V
chr12_-_36769054	5.377	NM_025359	Tspan13	tetraspanin 13
chr2_-_113669159	5.340		Scg5	secretogranin V
chr18_+_63137498	5.311		Napg	N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr19_+_29772410	5.300	NM_029993	Mlana	melan-A
chr5_-_122822329	5.279		1500011H22Rik	RIKEN cDNA 1500011H22 gene
chr1_-_82287990	5.261	NM_010570	Irs1	insulin receptor substrate 1
chr9_+_122481617	5.234		9530059O14Rik	RIKEN cDNA 9530059O14 gene
chrX_-_61530170	5.199	NM_178740	Slitrk4	SLIT and NTRK-like family, member 4
chr15_-_98507886	5.181	NM_172612	Rnd1	Rho family GTPase 1
chr7_-_107810868	5.165	NM_001163182 NM_013746	Plekhb1	pleckstrin homology domain containing, family B (evectins) member 1
chr6_+_83085799	5.158	NM_001136227	Rtkn	rhotekin
chr1_-_174128558	5.079		Pea15a	phosphoprotein enriched in astrocytes 15A
chr5_-_104542729	5.057		Sparcl1	SPARC-like 1
chr17_-_25969869	5.052		Stub1	STIP1 homology and U-Box containing protein 1
chr9_-_14419410	5.048	NM_001081395	Amotl1	angiomotin-like 1
chr18_-_12914177	5.025		Osbpl1a	oxysterol binding protein-like 1A
chr16_+_16213434	5.001	NM_026163	Pkp2	plakophilin 2
chr7_+_147949708	4.998	NM_021282	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1
chr9_-_54349409	4.993	NM_172771	Dmxl2	Dmx-like 2
chr1_-_99991958	4.964		Pam	peptidylglycine alpha-amidating monooxygenase
chr7_+_147949637	4.954		Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1
chr2_+_91096984	4.940		Pacsin3	protein kinase C and casein kinase substrate in neurons 3
chr13_-_58009653	4.940	NM_001166463 NM_001166464 NM_001166465 NM_001166466 NM_009262	Spock1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
chr9_-_95650735	4.927	NM_011643	Trpc1	transient receptor potential cation channel, subfamily C, member 1
chr11_-_118216591	4.922		Timp2	tissue inhibitor of metalloproteinase 2
chr6_+_115189004	4.922		Syn2	synapsin II
chr8_+_11448095	4.908		Col4a2	collagen, type IV, alpha 2
chr2_+_118687703	4.905	NM_019826	Ivd	isovaleryl coenzyme A dehydrogenase
chr5_+_89012596	4.877	NM_027530	Rufy3	RUN and FYVE domain containing 3
chr7_-_134732108	4.862	NM_001033040	Gm166	predicted gene 166
chr1_-_174136874	4.836	NM_011063	Pea15a	phosphoprotein enriched in astrocytes 15A
chr17_+_35960291	4.829	NM_008027	Flot1	flotillin 1
chr19_-_5085471	4.793	NM_001001885	Tmem151a	transmembrane protein 151A
chr5_-_5694033	4.741	NM_001103156 NM_001103157	Steap2	six transmembrane epithelial antigen of prostate 2
chrX_+_133371611	4.737		Plp1	proteolipid protein (myelin) 1
chr4_+_138012860	4.708		Camk2n1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr11_-_41814008	4.694	NM_008073	Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.90	6.46e-06	GO:0048468	cell development
2.18	2.12e-05	GO:0030030	cell projection organization
1.87	2.92e-05	GO:0022008	neurogenesis
2.23	6.47e-05	GO:0048666	neuron development
2.41	7.04e-05	GO:0031175	neuron projection development
1.37	9.42e-05	GO:0032502	developmental process
1.38	2.28e-04	GO:0007275	multicellular organismal development
1.66	2.43e-04	GO:0007399	nervous system development
2.34	4.57e-04	GO:0032990	cell part morphogenesis
8.34	7.12e-04	GO:0055021	regulation of cardiac muscle tissue growth
2.25	9.51e-04	GO:0019226	transmission of nerve impulse
2.25	9.51e-04	GO:0035637	multicellular organismal signaling
1.79	1.04e-03	GO:0048699	generation of neurons
5.29	1.09e-03	GO:0046620	regulation of organ growth
7.90	1.28e-03	GO:0055024	regulation of cardiac muscle tissue development
7.90	1.28e-03	GO:0060420	regulation of heart growth
1.38	1.29e-03	GO:0048856	anatomical structure development
2.27	1.85e-03	GO:0048858	cell projection morphogenesis
2.54	1.87e-03	GO:0007409	axonogenesis
1.93	2.22e-03	GO:0030182	neuron differentiation
2.69	4.06e-03	GO:0043062	extracellular structure organization
1.38	4.23e-03	GO:0048731	system development
2.21	5.14e-03	GO:0000904	cell morphogenesis involved in differentiation
2.35	5.69e-03	GO:0048812	neuron projection morphogenesis
1.31	7.65e-03	GO:0051179	localization
2.66	1.12e-02	GO:0060537	muscle tissue development
1.41	1.28e-02	GO:0030154	cell differentiation
2.31	1.48e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
1.40	1.89e-02	GO:0048869	cellular developmental process
1.91	3.12e-02	GO:0000902	cell morphogenesis
2.20	3.26e-02	GO:0007268	synaptic transmission
1.87	3.29e-02	GO:0032989	cellular component morphogenesis
1.92	4.00e-02	GO:0007267	cell-cell signaling
7.30	4.79e-02	GO:0060043	regulation of cardiac muscle cell proliferation

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.78	5.81e-07	GO:0042995	cell projection
1.20	5.90e-06	GO:0005737	cytoplasm
2.10	1.52e-05	GO:0045202	synapse
1.98	2.82e-05	GO:0043005	neuron projection
2.12	9.31e-05	GO:0044463	cell projection part
2.27	1.07e-04	GO:0031012	extracellular matrix
1.86	2.04e-04	GO:0030054	cell junction
1.23	3.03e-04	GO:0044444	cytoplasmic part
1.29	9.58e-04	GO:0071944	cell periphery
1.12	1.12e-03	GO:0005622	intracellular
5.75	1.46e-03	GO:0030672	synaptic vesicle membrane
2.10	1.50e-03	GO:0044456	synapse part
1.28	2.07e-03	GO:0005886	plasma membrane
2.02	5.03e-03	GO:0044297	cell body
2.12	6.38e-03	GO:0005578	proteinaceous extracellular matrix
2.11	6.89e-03	GO:0030425	dendrite
1.11	1.03e-02	GO:0044424	intracellular part
2.65	1.36e-02	GO:0033267	axon part
1.38	1.41e-02	GO:0044459	plasma membrane part
1.61	1.86e-02	GO:0031982	vesicle
1.97	1.87e-02	GO:0043025	neuronal cell body
1.47	2.57e-02	GO:0000267	cell fraction
2.87	2.76e-02	GO:0008021	synaptic vesicle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.30	9.59e-08	GO:0005515	protein binding
1.15	6.79e-06	GO:0005488	binding
2.04	9.34e-04	GO:0060589	nucleoside-triphosphatase regulator activity
2.25	4.37e-03	GO:0005083	small GTPase regulator activity
1.97	4.62e-03	GO:0030695	GTPase regulator activity
3.17	3.35e-02	GO:0005088	Ras guanyl-nucleotide exchange factor activity
1.56	4.05e-02	GO:0030234	enzyme regulator activity