Motif ID: LMO2.p2

Z-value: 1.967


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
Lmo2 16909 LIM domain only 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lmo2chr2_+_103809709,
chr2_+_103798150
-0.181.5e-02Click!


Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_41720091 49.371 NM_001040699
Mtmr7
myotubularin related protein 7
chr8_+_128519001 43.646 NM_008430
Kcnk1
potassium channel, subfamily K, member 1
chr8_+_128519295 40.662 Kcnk1
potassium channel, subfamily K, member 1
chrX_+_162676903 39.731 Gpm6b
glycoprotein m6b
chr14_-_55531726 39.465 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr15_+_78744862 35.528 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr4_-_133053867 32.869 Trnp1
TMF1-regulated nuclear protein 1
chr6_+_118016385 32.865 NM_027526
Rasgef1a
RasGEF domain family, member 1A
chr11_-_69419330 31.989 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr14_-_30534966 29.891 NM_009785
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr7_+_114514258 29.874 NM_021889
Syt9
synaptotagmin IX
chr2_+_49474840 29.324 Kif5c
kinesin family member 5C
chrX_+_162676870 29.002 NM_001177961
NM_001177962
NM_023122
Gpm6b


glycoprotein m6b


chr10_-_18463500 28.474 NM_001033258
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr12_+_110798661 27.050 Meg3
maternally expressed 3
chr2_+_157387284 26.808 Nnat
neuronatin
chr4_-_133054355 26.205 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr6_-_23789048 25.390 Cadps2
Ca2+-dependent activator protein for secretion 2
chr7_+_52955153 24.985 NM_009800
Car11
carbonic anhydrase 11
chr18_+_82753560 24.204 Mbp
myelin basic protein
chr2_-_113669229 23.967 Scg5
secretogranin V
chr2_-_113669243 23.817 NM_009162
Scg5
secretogranin V
chr11_+_92960603 23.419 NM_028296
Car10
carbonic anhydrase 10
chr8_+_12915892 23.067 NM_178076
Mcf2l
mcf.2 transforming sequence-like
chr4_-_151235861 22.754 NM_001081557
NM_001195565
Camta1

calmodulin binding transcription activator 1

chr6_-_77929660 22.697 NM_001109764
NM_009819
NM_145732
Ctnna2


catenin (cadherin associated protein), alpha 2


chr2_-_113669159 22.381 Scg5
secretogranin V
chr15_+_78744802 22.348 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr2_-_127481868 22.051 Mal
myelin and lymphocyte protein, T-cell differentiation protein
chr7_+_52955569 21.433 Car11
carbonic anhydrase 11
chr5_-_44492908 21.375 NM_001163577
NM_008935
Prom1

prominin 1

chr5_-_68238603 21.319 Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr2_+_49474775 21.304 NM_008449
Kif5c
kinesin family member 5C
chr6_-_77929543 21.281 Ctnna2
catenin (cadherin associated protein), alpha 2
chr6_-_25639812 21.241 Gpr37
G protein-coupled receptor 37
chr9_-_107134182 21.064 NM_153413
Dock3
dedicator of cyto-kinesis 3
chr15_+_78744576 20.790 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr13_+_97841524 19.955 NM_001100458
Fam169a
family with sequence similarity 169, member A
chr6_-_25639835 19.809 Gpr37
G protein-coupled receptor 37
chr7_+_64845887 19.790 NM_001038701
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr9_+_110147867 19.785 Cspg5
chondroitin sulfate proteoglycan 5
chr6_-_77929685 19.224 Ctnna2
catenin (cadherin associated protein), alpha 2
chr2_+_132607013 19.118 NM_007694
Chgb
chromogranin B
chr11_-_69419419 19.066 NM_013415
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr11_-_46125777 18.913 NM_133769
Cyfip2
cytoplasmic FMR1 interacting protein 2
chr19_-_45890238 18.776 NM_030716
NM_145703
NM_145704
Kcnip2


Kv channel-interacting protein 2


chr2_+_132607432 18.704 Chgb
chromogranin B
chr13_-_96214609 18.680 NM_198408
Crhbp
corticotropin releasing hormone binding protein
chr2_+_132607398 18.408 Chgb
chromogranin B
chr12_+_109572514 18.358 NM_010010
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr13_-_58009599 18.250 Spock1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
chr2_+_132607408 18.244 Chgb
chromogranin B
chr5_-_34630913 17.738 NM_001015039
Zfyve28
zinc finger, FYVE domain containing 28
chr16_-_67621054 17.541 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr13_-_100286521 17.420 NM_008634
Mtap1b
microtubule-associated protein 1B
chr19_+_45635070 17.284 NM_172639
Dpcd
deleted in primary ciliary dyskinesia
chr17_+_35373506 17.117 NM_023179
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr13_+_104899814 16.849 Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr18_-_43059156 16.847 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr1_-_166388431 16.694 NM_009721
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_-_21856445 16.016 NM_010487
Elavl3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr5_-_68238444 15.723 Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr9_+_103014463 15.669 Rab6b
RAB6B, member RAS oncogene family
chr6_-_23789259 15.643 NM_153163
Cadps2
Ca2+-dependent activator protein for secretion 2
chr14_-_57752270 15.114 NM_001010937
Gjb6
gap junction protein, beta 6
chr13_+_93195850 15.097 NM_175455
Ankrd34b
ankyrin repeat domain 34B
chrX_+_162676910 15.086 Gpm6b
glycoprotein m6b
chr6_+_4853319 15.022 NM_181595
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr9_+_103014445 14.993 Rab6b
RAB6B, member RAS oncogene family
chr11_+_101017197 14.909 NM_134028
Tubg2
tubulin, gamma 2
chr9_+_120213190 14.808 NM_144557
Myrip
myosin VIIA and Rab interacting protein
chr2_-_73613381 14.664 NM_001113246
NM_001166603
Chn1

chimerin (chimaerin) 1

chr3_+_64913289 14.588 Kcnab1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr6_+_48487567 14.572 NM_133764
Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr6_+_48487648 14.553 Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr9_-_42924626 14.374 NM_001034863
Tmem136
transmembrane protein 136
chr2_-_25174498 14.132 Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr11_+_68505616 14.060 Myh10
myosin, heavy polypeptide 10, non-muscle
chr2_+_70400179 14.051 NM_008077
Gad1
glutamic acid decarboxylase 1
chr1_+_78306890 14.010 NM_001004173
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr3_+_145421870 14.009 Ddah1
dimethylarginine dimethylaminohydrolase 1
chr1_-_89406861 14.001 NM_019867
Ngef
neuronal guanine nucleotide exchange factor
chr4_+_84851330 13.885 NM_019535
Sh3gl2
SH3-domain GRB2-like 2
chr11_-_116274124 13.830 Rnf157
ring finger protein 157
chr2_+_25284190 13.820 NM_007379
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr4_-_119165183 13.707 NM_177572
Rimkla
ribosomal modification protein rimK-like family member A
chr11_+_68505612 13.486 Myh10
myosin, heavy polypeptide 10, non-muscle
chr13_-_100286446 13.420 Mtap1b
microtubule-associated protein 1B
chr17_-_57226987 13.412 NM_009451
Tubb4
tubulin, beta 4
chr18_-_31606908 13.399 NM_009308
Syt4
synaptotagmin IV
chr8_-_112692071 13.349 NM_007586
Calb2
calbindin 2
chr17_+_81343933 13.282 NM_026516
Tmem178
transmembrane protein 178
chr19_+_10525829 13.231


chr19_+_47089736 13.161 Ina
internexin neuronal intermediate filament protein, alpha
chr11_-_35793590 13.060 NM_170779
Wwc1
WW, C2 and coiled-coil domain containing 1
chr14_-_57752102 12.917 Gjb6
gap junction protein, beta 6
chr1_+_34068669 12.881 NM_133833
NM_134448
Dst

dystonin

chr15_+_98465193 12.749 NM_007581
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr13_-_49243351 12.743 NM_029361
Wnk2
WNK lysine deficient protein kinase 2
chr18_+_38115192 12.601 NM_153793
Rell2
RELT-like 2
chr16_+_6349108 12.595 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_+_37637027 12.581 NM_007765
Crmp1
collapsin response mediator protein 1
chr14_+_104049411 12.486 Slain1
SLAIN motif family, member 1
chr2_-_121632749 12.475 NM_172673
Frmd5
FERM domain containing 5
chr12_+_91050912 12.362 Nrxn3
neurexin III
chr2_-_25174662 12.354 NM_001177656
NM_001177657
NM_008169
Grin1


glutamate receptor, ionotropic, NMDA1 (zeta 1)


chr9_-_75531734 12.314 NM_001164790
NM_009130
Scg3

secretogranin III

chr6_-_77929575 12.303 Ctnna2
catenin (cadherin associated protein), alpha 2
chr11_+_71564481 12.283 Wscd1
WSC domain containing 1
chr12_+_113960424 12.270 AW555464
expressed sequence AW555464
chrX_+_155852439 12.206 NM_001081124
Mtap7d2
MAP7 domain containing 2
chr17_+_27792487 12.164 Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr2_+_90729768 12.116 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr17_+_27792587 12.113 NM_011861
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr11_-_115229039 12.051 C630004H02Rik
RIKEN cDNA C630004H02 gene
chr8_-_4217275 11.968 NM_207203
BC068157
cDNA sequence BC068157
chr8_-_4259126 11.934 NM_183315
Ctxn1
cortexin 1
chr1_-_84692352 11.913 Dner
delta/notch-like EGF-related receptor
chr5_+_37259906 11.911 Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr12_+_113960530 11.906 AW555464
expressed sequence AW555464
chr3_+_145421621 11.885 NM_026993
Ddah1
dimethylarginine dimethylaminohydrolase 1
chr11_+_42233258 11.882 NM_008070
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr7_+_4071087 11.694 NM_001001454
NM_001109765
NM_021324
Ttyh1


tweety homolog 1 (Drosophila)


chr7_-_30066642 11.670 Spint2
serine protease inhibitor, Kunitz type 2
chr5_+_25265761 11.588 NM_001004365
Actr3b
ARP3 actin-related protein 3 homolog B (yeast)
chr10_-_80945379 11.547 Celf5
CUGBP, Elav-like family member 5
chr8_-_128422192 11.383 NM_175561
Pcnxl2
pecanex-like 2 (Drosophila)
chr3_+_156224757 11.338 NM_001039094
NM_177274
Negr1

neuronal growth regulator 1

chr4_+_101169252 11.311 NM_198412
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_-_68238654 11.102 NM_001038999
NM_009727
Atp8a1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr13_-_58009653 11.083 NM_001166463
NM_001166464
NM_001166465
NM_001166466
NM_009262
Spock1




sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1




chr16_-_34263272 11.082 Kalrn
kalirin, RhoGEF kinase
chr14_-_119324535 11.033 Dzip1
DAZ interacting protein 1
chr4_+_108551674 11.008 NM_023537
Rab3b
RAB3B, member RAS oncogene family
chr9_+_107838164 10.905 NM_145621
Camkv
CaM kinase-like vesicle-associated
chr7_+_129432810 10.891 Prkcb
protein kinase C, beta
chr4_+_84851440 10.860 Sh3gl2
SH3-domain GRB2-like 2
chr13_+_58909254 10.845 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr4_+_15808409 10.802 NM_009788
Calb1
calbindin 1
chr13_+_58909648 10.686 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr5_+_37259780 10.683 NM_172994
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr4_+_137263376 10.618 Rap1gap
Rap1 GTPase-activating protein
chr13_-_25029458 10.478 NM_172532
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr1_+_179372452 10.475 Zfp238
zinc finger protein 238
chr1_+_74379182 10.472 NM_019999
Pnkd
paroxysmal nonkinesiogenic dyskinesia
chr6_+_114232618 10.464 NM_178703
Slc6a1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr6_-_8728094 10.457 Ica1
islet cell autoantigen 1
chr4_+_129662110 10.402 Bai2
brain-specific angiogenesis inhibitor 2
chr13_-_92901406 10.376 NM_009027
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr7_-_31230577 10.374 NM_007467
Aplp1
amyloid beta (A4) precursor-like protein 1
chr3_+_108163704 10.333 Sort1
sortilin 1
chr9_+_75161942 10.216 NM_138719
Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr11_-_74403603 10.204 NM_001015046
Rap1gap2
RAP1 GTPase activating protein 2
chr6_-_126658429 10.178


chr10_-_80945445 10.162 NM_176954
Celf5
CUGBP, Elav-like family member 5
chr8_-_97220127 10.139 NM_026385
Pllp
plasma membrane proteolipid
chr7_-_30066867 10.136 Spint2
serine protease inhibitor, Kunitz type 2
chr14_-_62911797 10.089 NM_173419
Dleu7
deleted in lymphocytic leukemia, 7
chr7_+_25266986 10.075 NM_153112
Cadm4
cell adhesion molecule 4
chr16_-_34263047 10.074 Kalrn
kalirin, RhoGEF kinase
chr7_-_31230463 10.069 Aplp1
amyloid beta (A4) precursor-like protein 1
chr9_-_86775282 10.044 Snap91
synaptosomal-associated protein 91
chr4_-_135050358 9.951 NM_028995
Nipal3
NIPA-like domain containing 3
chr3_-_88576415 9.897 NM_018804
Syt11
synaptotagmin XI
chr11_+_101017307 9.872 Tubg2
tubulin, gamma 2
chr7_-_30066910 9.842 NM_001082548
NM_011464
Spint2

serine protease inhibitor, Kunitz type 2

chrX_+_71550562 9.828 Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr6_+_21166108 9.818 NM_019697
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr15_-_84388113 9.800 Ldoc1l
leucine zipper, down-regulated in cancer 1-like
chr3_+_64913564 9.769 NM_010597
Kcnab1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr15_-_84387921 9.738 Ldoc1l
leucine zipper, down-regulated in cancer 1-like
chr12_-_100139666 9.706 NM_001081191
Eml5
echinoderm microtubule associated protein like 5
chrX_-_131543723 9.681 NM_175446
Zmat1
zinc finger, matrin type 1
chr16_+_91270319 9.617 Olig1
oligodendrocyte transcription factor 1
chr13_+_58909236 9.612 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr10_-_80306743 9.589 NM_001013758
Lingo3
leucine rich repeat and Ig domain containing 3
chr7_+_134094045 9.550 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr8_+_4493404 9.542 NM_026058
Lass4
LAG1 homolog, ceramide synthase 4
chr15_-_33617572 9.502 NM_001085421
Tspyl5
testis-specific protein, Y-encoded-like 5
chr7_-_31230564 9.488 Aplp1
amyloid beta (A4) precursor-like protein 1
chr8_+_15032567 9.488 Kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr13_+_58909168 9.472 NM_001025074
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr12_+_16660521 9.458 Ntsr2
neurotensin receptor 2
chr15_-_37721754 9.452 NM_001170866
Ncald
neurocalcin delta
chr15_-_37722161 9.415 NM_134094
Ncald
neurocalcin delta
chr17_-_26338254 9.414 NM_008113
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr10_-_32609590 9.410 NM_001013411
NM_001025286
Nkain2

Na+/K+ transporting ATPase interacting 2

chrX_-_70905384 9.409 Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr8_+_112603609 9.387 NM_175480
Zfp612
zinc finger protein 612
chr2_-_170232008 9.385 Bcas1
breast carcinoma amplified sequence 1
chr7_+_4874478 9.367 Nat14
N-acetyltransferase 14
chr8_+_4493451 9.306 Lass4
LAG1 homolog, ceramide synthase 4
chr15_+_79059802 9.242 NM_001045558
Pick1
protein interacting with C kinase 1
chr14_-_122196929 9.235 NM_134074
Dock9
dedicator of cytokinesis 9
chr7_+_133416177 9.193 Sbk1
SH3-binding kinase 1
chr14_-_71035662 9.123 Epb4.9
erythrocyte protein band 4.9
chr15_-_64753721 9.112 NM_009623
Adcy8
adenylate cyclase 8
chr9_-_86775154 9.099 NM_013669
Snap91
synaptosomal-associated protein 91
chr16_+_7069927 9.086 NM_183188
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_-_26338106 9.081 Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.38 9.99e-12 GO:0051179 localization
1.68 1.15e-11 GO:0007399 nervous system development
1.41 4.86e-11 GO:0006810 transport
1.40 1.07e-10 GO:0051234 establishment of localization
1.81 2.60e-10 GO:0048699 generation of neurons
1.77 4.36e-10 GO:0022008 neurogenesis
1.37 8.25e-08 GO:0048731 system development
1.35 1.36e-07 GO:0048856 anatomical structure development
1.32 5.17e-07 GO:0007275 multicellular organismal development
1.42 5.69e-07 GO:0065008 regulation of biological quality
2.17 1.10e-06 GO:0045664 regulation of neuron differentiation
2.04 1.82e-06 GO:0050767 regulation of neurogenesis
1.29 2.50e-06 GO:0032502 developmental process
2.47 3.37e-06 GO:0010975 regulation of neuron projection development
1.44 1.08e-05 GO:0023051 regulation of signaling
1.87 2.15e-05 GO:0060284 regulation of cell development
1.52 2.57e-05 GO:0051641 cellular localization
1.90 3.06e-05 GO:0051960 regulation of nervous system development
1.94 3.75e-05 GO:0019226 transmission of nerve impulse
1.94 3.75e-05 GO:0035637 multicellular organismal signaling
1.35 5.71e-05 GO:0048869 cellular developmental process
1.55 9.71e-05 GO:0051649 establishment of localization in cell
1.35 1.03e-04 GO:0030154 cell differentiation
2.16 2.69e-04 GO:0031344 regulation of cell projection organization
1.76 6.56e-04 GO:0007267 cell-cell signaling
1.52 7.11e-04 GO:0051128 regulation of cellular component organization
1.96 8.40e-04 GO:0007268 synaptic transmission
1.68 1.02e-03 GO:0030030 cell projection organization
1.65 1.13e-03 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
4.63 1.64e-03 GO:0010970 microtubule-based transport
4.63 1.64e-03 GO:0030705 cytoskeleton-dependent intracellular transport
1.95 2.25e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.72 3.21e-03 GO:0072521 purine-containing compound metabolic process
1.61 3.99e-03 GO:0030182 neuron differentiation
2.05 4.32e-03 GO:0050804 regulation of synaptic transmission
1.55 4.46e-03 GO:0007154 cell communication
1.74 6.87e-03 GO:0006163 purine nucleotide metabolic process
1.98 6.96e-03 GO:0051969 regulation of transmission of nerve impulse
1.63 7.89e-03 GO:0006753 nucleoside phosphate metabolic process
1.63 7.89e-03 GO:0009117 nucleotide metabolic process
2.54 9.65e-03 GO:0006836 neurotransmitter transport
1.33 1.23e-02 GO:0051239 regulation of multicellular organismal process
3.31 1.27e-02 GO:0007269 neurotransmitter secretion
3.31 1.27e-02 GO:0050773 regulation of dendrite development
1.37 1.37e-02 GO:0009966 regulation of signal transduction
1.90 1.58e-02 GO:0031644 regulation of neurological system process
1.39 1.73e-02 GO:0010646 regulation of cell communication
1.39 1.92e-02 GO:0035556 intracellular signal transduction
1.44 1.99e-02 GO:0048468 cell development
1.31 2.13e-02 GO:0044281 small molecule metabolic process
1.46 2.13e-02 GO:0045595 regulation of cell differentiation
1.52 2.18e-02 GO:0046483 heterocycle metabolic process
1.22 2.93e-02 GO:0016043 cellular component organization
1.77 2.93e-02 GO:0009141 nucleoside triphosphate metabolic process
1.72 3.09e-02 GO:0031175 neuron projection development
1.79 3.17e-02 GO:0009199 ribonucleoside triphosphate metabolic process
2.59 3.54e-02 GO:0001505 regulation of neurotransmitter levels
3.18 4.28e-02 GO:0048168 regulation of neuronal synaptic plasticity
1.76 4.99e-02 GO:0009144 purine nucleoside triphosphate metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.25 1.04e-20 GO:0005737 cytoplasm
2.35 7.19e-19 GO:0045202 synapse
2.49 1.86e-15 GO:0044456 synapse part
2.11 2.35e-15 GO:0043005 neuron projection
1.27 7.11e-14 GO:0044444 cytoplasmic part
1.73 8.33e-14 GO:0042995 cell projection
1.15 9.57e-14 GO:0005622 intracellular
1.15 1.31e-12 GO:0044424 intracellular part
1.95 1.63e-12 GO:0030054 cell junction
1.32 8.85e-11 GO:0071944 cell periphery
1.31 5.51e-10 GO:0005886 plasma membrane
2.30 5.29e-09 GO:0030424 axon
1.96 3.68e-08 GO:0044463 cell projection part
1.07 6.56e-07 GO:0005623 cell
1.07 6.56e-07 GO:0044464 cell part
2.07 1.12e-06 GO:0030425 dendrite
1.99 1.45e-06 GO:0043025 neuronal cell body
1.58 1.49e-06 GO:0005624 membrane fraction
1.38 2.32e-06 GO:0044459 plasma membrane part
1.55 2.40e-06 GO:0005626 insoluble fraction
1.48 2.95e-06 GO:0000267 cell fraction
1.92 5.86e-06 GO:0044297 cell body
1.12 1.78e-05 GO:0043229 intracellular organelle
1.12 2.25e-05 GO:0043226 organelle
1.56 4.95e-05 GO:0031982 vesicle
1.57 6.82e-05 GO:0031410 cytoplasmic vesicle
2.68 7.71e-05 GO:0008021 synaptic vesicle
2.34 8.05e-05 GO:0030136 clathrin-coated vesicle
1.12 1.41e-04 GO:0016020 membrane
2.22 1.57e-04 GO:0030135 coated vesicle
2.23 1.74e-04 GO:0045211 postsynaptic membrane
1.36 2.80e-04 GO:0005856 cytoskeleton
2.26 8.03e-04 GO:0019717 synaptosome
2.27 1.07e-03 GO:0033267 axon part
1.55 3.76e-03 GO:0031988 membrane-bounded vesicle
1.41 4.00e-03 GO:0044430 cytoskeletal part
1.83 9.12e-03 GO:0005911 cell-cell junction
2.58 9.32e-03 GO:0043197 dendritic spine
1.96 1.07e-02 GO:0034702 ion channel complex
1.53 1.08e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.10 1.46e-02 GO:0043227 membrane-bounded organelle
2.51 1.49e-02 GO:0044309 neuron spine
1.37 1.71e-02 GO:0005794 Golgi apparatus
2.43 1.76e-02 GO:0030426 growth cone
2.98 1.81e-02 GO:0005913 cell-cell adherens junction
1.10 2.16e-02 GO:0043231 intracellular membrane-bounded organelle
2.34 3.29e-02 GO:0030427 site of polarized growth
1.20 3.41e-02 GO:0043234 protein complex
1.47 3.52e-02 GO:0015630 microtubule cytoskeleton
1.27 4.84e-02 GO:0005829 cytosol

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.13 2.05e-08 GO:0005488 binding
1.21 2.38e-08 GO:0005515 protein binding
1.84 1.16e-07 GO:0008092 cytoskeletal protein binding
1.88 2.42e-06 GO:0060589 nucleoside-triphosphatase regulator activity
1.89 2.52e-06 GO:0030695 GTPase regulator activity
2.04 3.80e-05 GO:0005083 small GTPase regulator activity
1.46 1.61e-03 GO:0030234 enzyme regulator activity
1.40 2.23e-03 GO:0005215 transporter activity
1.77 4.11e-03 GO:0003779 actin binding
1.25 1.27e-02 GO:0000166 nucleotide binding
1.41 1.77e-02 GO:0022857 transmembrane transporter activity
2.16 1.95e-02 GO:0005516 calmodulin binding
1.19 1.96e-02 GO:0046872 metal ion binding
1.27 2.36e-02 GO:0032555 purine ribonucleotide binding
1.41 2.37e-02 GO:0016301 kinase activity
1.27 2.46e-02 GO:0032553 ribonucleotide binding
1.60 2.81e-02 GO:0015267 channel activity
1.27 2.82e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.39 2.87e-02 GO:0022892 substrate-specific transporter activity
1.60 3.07e-02 GO:0022803 passive transmembrane transporter activity
1.26 3.14e-02 GO:0017076 purine nucleotide binding
1.17 4.81e-02 GO:0043169 cation binding