• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: MTF1.p2

Z-value: 2.688

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_68298129	64.173		Schip1	schwannomin interacting protein 1
chr15_+_30102306	57.794	NM_008729	Ctnnd2	catenin (cadherin associated protein), delta 2
chr4_-_151235861	55.054	NM_001081557 NM_001195565	Camta1	calmodulin binding transcription activator 1
chr11_-_5965743	53.900	NM_001174053 NM_001174054 NM_007595	Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chr13_+_19040215	51.797	NM_175007	Amph	amphiphysin
chr8_+_96696677	51.161		Mt2	metallothionein 2
chr8_+_96703145	47.067		Mt1	metallothionein 1
chrX_+_162676870	46.679	NM_001177961 NM_001177962 NM_023122	Gpm6b	glycoprotein m6b
chr8_+_96696512	43.679	NM_008630	Mt2	metallothionein 2
chrX_+_53985133	43.038	NM_001077361	Fhl1	four and a half LIM domains 1
chr4_+_129662110	42.937		Bai2	brain-specific angiogenesis inhibitor 2
chr4_+_148960604	42.694	NM_023051	Clstn1	calsyntenin 1
chr4_+_129662284	42.628	NM_173071	Bai2	brain-specific angiogenesis inhibitor 2
chr11_-_5965555	42.135		Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chrX_+_78315963	40.888	NM_138751	Tmem47	transmembrane protein 47
chr7_+_53651811	39.932	NM_008421 NM_001112739	Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1
chr5_+_34339258	39.795		Nat8l	N-acetyltransferase 8-like
chr11_-_5965544	37.328		Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chrX_+_162676903	37.126		Gpm6b	glycoprotein m6b
chr17_+_25945986	36.347	NM_001164225	Fbxl16	F-box and leucine-rich repeat protein 16
chr1_-_33964439	35.066	NM_177235	Bend6	BEN domain containing 6
chr13_-_69138229	33.658		Adcy2	adenylate cyclase 2
chr4_+_148960536	33.356		Clstn1	calsyntenin 1
chr5_+_34339351	32.881		Nat8l	N-acetyltransferase 8-like
chr13_-_78337844	32.304		Nr2f1	nuclear receptor subfamily 2, group F, member 1
chr2_-_168567436	29.604		Atp9a	ATPase, class II, type 9A
chr17_+_69506165	29.513		Epb4.1l3	erythrocyte protein band 4.1-like 3
chr7_+_138079669	29.077	NM_019564	Htra1	HtrA serine peptidase 1
chr8_+_116729508	28.627	NM_173016	Vat1l	vesicle amine transport protein 1 homolog-like (T. californica)
chr4_-_57003214	28.610	NM_001142965	6430704M03Rik	RIKEN cDNA 6430704M03 gene
chr8_+_126177709	28.503	NM_133955	Rhou	ras homolog gene family, member U
chr17_-_66799086	28.500	NM_001114098 NM_172963	1110012J17Rik	RIKEN cDNA 1110012J17 gene
chr13_-_69138164	28.236		Adcy2	adenylate cyclase 2
chr15_+_87374667	27.922		Fam19a5	family with sequence similarity 19, member A5
chr1_+_194014650	27.578		Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1
chr11_+_68505416	27.510	NM_175260	Myh10	myosin, heavy polypeptide 10, non-muscle
chr15_-_44619541	27.374	NM_001032727 NM_176998	Sybu	syntabulin (syntaxin-interacting)
chr16_+_91270009	27.204	NM_016968	Olig1	oligodendrocyte transcription factor 1
chr1_-_37776633	26.878	NM_028096	2010300C02Rik	RIKEN cDNA 2010300C02 gene
chr14_-_55734213	26.876	NM_001003829	Jph4	junctophilin 4
chr2_-_168567422	26.279		Atp9a	ATPase, class II, type 9A
chr1_-_84692352	26.162		Dner	delta/notch-like EGF-related receptor
chr4_-_133053867	25.591		Trnp1	TMF1-regulated nuclear protein 1
chr10_-_79602040	25.469		Dos	downstream of Stk11
chr12_-_112615555	25.170		Cdc42bpb	CDC42 binding protein kinase beta
chr1_+_63492447	24.299	NM_001177600 NM_011780	Adam23	a disintegrin and metallopeptidase domain 23
chr8_+_96702981	24.159	NM_013602	Mt1	metallothionein 1
chr17_+_86567513	23.912		Prkce	protein kinase C, epsilon
chr2_-_80421054	23.562	NM_016965	Nckap1	NCK-associated protein 1
chr4_-_154735351	23.348	NM_008860	Prkcz	protein kinase C, zeta
chr3_-_57651409	23.248		Pfn2	profilin 2
chr2_+_28061156	23.145	NM_001038612 NM_019498	Olfm1	olfactomedin 1
chr15_-_75920355	22.980	NM_144847	Nrbp2	nuclear receptor binding protein 2
chr2_+_28048779	22.844		Olfm1	olfactomedin 1
chr9_-_53823107	22.823	NM_177769	Elmod1	ELMO domain containing 1
chr13_-_78338131	22.761	NM_010151	Nr2f1	nuclear receptor subfamily 2, group F, member 1
chr8_-_87323958	22.442		Nfix	nuclear factor I/X
chr17_+_69506083	21.897	NM_013813	Epb4.1l3	erythrocyte protein band 4.1-like 3
chr5_-_8367951	21.773	NM_001007220 NM_001007221 NM_001098225	Adam22	a disintegrin and metallopeptidase domain 22
chr8_+_96703174	21.705		Mt1	metallothionein 1
chr3_-_152331083	21.383	NM_001081277	Ak5	adenylate kinase 5
chrX_+_53984926	21.204	NM_010211	Fhl1	four and a half LIM domains 1
chr15_-_78034648	21.125		Pvalb	parvalbumin
chr12_+_112997057	21.110	NM_001025360 NM_001081959 NM_008450	Klc1	kinesin light chain 1
chrX_+_78316003	21.091		Tmem47	transmembrane protein 47
chr9_+_89804612	21.039	NM_001039655 NM_011245	Rasgrf1	RAS protein-specific guanine nucleotide-releasing factor 1
chr13_+_58907999	20.937		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr1_+_194014677	20.777	NM_001038607 NM_010600	Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1
chr7_-_148379844	20.617	NM_001130443 NM_001130444 NM_008284	Hras1	Harvey rat sarcoma virus oncogene 1
chr6_-_113991945	20.472	NM_009723	Atp2b2	ATPase, Ca++ transporting, plasma membrane 2
chr6_+_117961386	20.445		Rasgef1a	RasGEF domain family, member 1A
chr13_-_52626022	20.279		Diras2	DIRAS family, GTP-binding RAS-like 2
chr1_-_191167231	20.229	NM_001159850	Kcnk2	potassium channel, subfamily K, member 2
chr9_-_75459046	20.185		Tmod2	tropomodulin 2
chr9_-_75458865	20.084		Tmod2	tropomodulin 2
chr15_-_78034565	20.000	NM_013645	Pvalb	parvalbumin
chr15_+_100701068	19.958	NM_001077499	Scn8a	sodium channel, voltage-gated, type VIII, alpha
chr17_+_70318530	19.869		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr10_-_70062025	19.706	NM_178621	Phyhipl	phytanoyl-CoA hydroxylase interacting protein-like
chr16_-_85173930	19.660		App	amyloid beta (A4) precursor protein
chr16_-_85173978	19.650		App	amyloid beta (A4) precursor protein
chr2_+_90729768	19.648		C1qtnf4	C1q and tumor necrosis factor related protein 4
chr8_-_47296201	19.641	NM_007450	Slc25a4	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr7_-_148379755	19.509		Hras1	Harvey rat sarcoma virus oncogene 1
chr16_-_85173918	19.434		App	amyloid beta (A4) precursor protein
chr17_+_86567003	19.384	NM_011104	Prkce	protein kinase C, epsilon
chr4_+_101169252	19.381	NM_198412	Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr13_-_69138418	19.336	NM_153534	Adcy2	adenylate cyclase 2
chr2_+_28048592	19.322	NM_001038613 NM_001038614	Olfm1	olfactomedin 1
chr13_+_58907929	19.204		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr10_+_59569206	19.199		Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr19_-_7062118	18.971	NM_001185164 NM_011697	Vegfb	vascular endothelial growth factor B
chr16_-_85173851	18.599		App	amyloid beta (A4) precursor protein
chr19_-_7061867	18.585		Vegfb	vascular endothelial growth factor B
chr1_-_177422520	18.444		Rgs7	regulator of G protein signaling 7
chr14_-_24824081	18.443		Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr16_-_85173944	18.417	NM_001198823 NM_001198824 NM_001198825 NM_001198826 NM_007471	App	amyloid beta (A4) precursor protein
chr10_+_74429876	18.252	NM_010311	Gnaz	guanine nucleotide binding protein, alpha z subunit
chr6_+_88674398	18.208	NM_001166249 NM_011844	Mgll	monoglyceride lipase
chr9_-_107134182	18.203	NM_153413	Dock3	dedicator of cyto-kinesis 3
chr7_-_150646883	18.195	NM_001161624 NM_009876	Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)
chr9_-_53822931	18.087		Elmod1	ELMO domain containing 1
chr17_+_70318387	18.067		Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr4_-_154772070	18.046	NM_008072	Gabrd	gamma-aminobutyric acid (GABA) A receptor, subunit delta
chr1_-_173126368	18.042	NM_025557	Pcp4l1	Purkinje cell protein 4-like 1
chr10_-_70061996	17.692		Phyhipl	phytanoyl-CoA hydroxylase interacting protein-like
chr1_-_84281018	17.675		Pid1	phosphotyrosine interaction domain containing 1
chr8_+_11313002	17.426		Col4a2	collagen, type IV, alpha 2
chr8_-_92872139	17.418	NM_172913	Tox3	TOX high mobility group box family member 3
chr2_+_90730089	17.390		C1qtnf4	C1q and tumor necrosis factor related protein 4
chr6_-_23789259	17.373	NM_153163	Cadps2	Ca2+-dependent activator protein for secretion 2
chr15_+_78744862	17.289		Pdxp	pyridoxal (pyridoxine, vitamin B6) phosphatase
chr16_-_4420415	17.265		Adcy9	adenylate cyclase 9
chr1_-_89406861	17.185	NM_019867	Ngef	neuronal guanine nucleotide exchange factor
chr5_+_15440508	16.825	NM_001110843 NM_001110844 NM_001110845 NM_001110846 NM_009784	Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1
chr3_-_125641429	16.738	NM_011674	Ugt8a	UDP galactosyltransferase 8A
chr8_+_121971001	16.733		Necab2	N-terminal EF-hand calcium binding protein 2
chr17_+_44215761	16.600	NM_032003 NM_001168620	Enpp5	ectonucleotide pyrophosphatase/phosphodiesterase 5
chr12_+_114378688	16.557		Crip2	cysteine rich protein 2
chr11_+_100436316	16.517		Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase
chr14_+_28435613	16.486	NM_177814	Erc2	ELKS/RAB6-interacting/CAST family member 2
chr5_+_34339551	16.470		Nat8l	N-acetyltransferase 8-like
chr9_-_62384483	16.444		Coro2b	coronin, actin binding protein, 2B
chr9_+_107838164	16.409	NM_145621	Camkv	CaM kinase-like vesicle-associated
chr15_-_95358306	16.370		Nell2	NEL-like 2 (chicken)
chr12_+_114378368	16.334	NM_024223	Crip2	cysteine rich protein 2
chr5_-_122952179	16.333		Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr5_-_52957466	16.232		Lgi2	leucine-rich repeat LGI family, member 2
chr7_-_88599560	16.227	NM_007755	Cpeb1	cytoplasmic polyadenylation element binding protein 1
chr17_+_44215851	16.225		Enpp5	ectonucleotide pyrophosphatase/phosphodiesterase 5
chr3_+_55046548	16.193		Dclk1	doublecortin-like kinase 1
chrX_+_20265522	16.183		Cdk16	cyclin-dependent kinase 16
chr6_+_4853319	16.134	NM_181595	Ppp1r9a	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr7_-_74904546	16.133	NM_183312 NM_201639 NM_207663	Synm	synemin, intermediate filament protein
chr15_+_78744576	16.064		Pdxp	pyridoxal (pyridoxine, vitamin B6) phosphatase
chr2_+_156301651	16.020		Epb4.1l1	erythrocyte protein band 4.1-like 1
chr11_+_100436283	16.001		Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase
chr2_-_168567602	15.961		Atp9a	ATPase, class II, type 9A
chr7_-_150646758	15.903		Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)
chr11_+_100436228	15.898	NM_009923	Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase
chrX_+_5624820	15.688		Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr1_+_72871060	15.682	NM_008342	Igfbp2	insulin-like growth factor binding protein 2
chr1_-_186823350	15.562	NM_145515	Mark1	MAP/microtubule affinity-regulating kinase 1
chr11_+_68901989	15.451		Vamp2	vesicle-associated membrane protein 2
chr11_+_71564481	15.383		Wscd1	WSC domain containing 1
chr8_+_121970569	15.347	NM_054095	Necab2	N-terminal EF-hand calcium binding protein 2
chr2_-_130468507	15.291	NM_197945	Prosapip1	ProSAPiP1 protein
chr4_-_57002965	15.192		6430704M03Rik	RIKEN cDNA 6430704M03 gene
chrX_+_7215705	15.139	NM_009305	Syp	synaptophysin
chr3_-_138738020	15.078		Rap1gds1	RAP1, GTP-GDP dissociation stimulator 1
chr9_+_120213190	15.027	NM_144557	Myrip	myosin VIIA and Rab interacting protein
chr16_+_94592307	15.027	NM_009441	Ttc3	tetratricopeptide repeat domain 3
chr8_-_11312686	14.913		Col4a1	collagen, type IV, alpha 1
chr11_+_68505616	14.882		Myh10	myosin, heavy polypeptide 10, non-muscle
chr4_+_43394824	14.868	NM_001037709	Rusc2	RUN and SH3 domain containing 2
chr2_-_77654669	14.833	NM_178723	Zfp385b	zinc finger protein 385B
chr11_+_17059301	14.730		Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
chr15_+_78744328	14.692	NM_020271	Pdxp	pyridoxal (pyridoxine, vitamin B6) phosphatase
chr18_-_43597640	14.689		Dpysl3	dihydropyrimidinase-like 3
chr5_-_72049479	14.574	NM_010251	Gabra4	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr5_-_72049058	14.519		Gabra4	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr8_+_14095873	14.305	NM_001145965 NM_172910	Dlgap2	discs, large (Drosophila) homolog-associated protein 2
chr11_-_70846926	14.266		6330403K07Rik	RIKEN cDNA 6330403K07 gene
chr11_+_100436346	14.178		Cnp	2',3'-cyclic nucleotide 3' phosphodiesterase
chr16_+_8513513	14.142	NM_001170978 NM_172961	Abat	4-aminobutyrate aminotransferase
chr19_+_16207300	14.127	NM_008139	Gnaq	guanine nucleotide binding protein, alpha q polypeptide
chr11_+_53380870	14.044	NM_008443	Kif3a	kinesin family member 3A
chr1_-_193141946	13.980	NM_025424	Nenf	neuron derived neurotrophic factor
chr15_+_87455659	13.944	NM_134096	Fam19a5	family with sequence similarity 19, member A5
chr6_-_23789048	13.872		Cadps2	Ca2+-dependent activator protein for secretion 2
chr1_-_166387998	13.827		Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_-_138738059	13.773		Rap1gds1	RAP1, GTP-GDP dissociation stimulator 1
chr3_+_55046447	13.724	NM_001111053 NM_001195538 NM_019978	Dclk1	doublecortin-like kinase 1
chr18_-_20904585	13.709	NM_019737	B4galt6	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
chr19_+_6427922	13.558	NM_020253	Nrxn2	neurexin II
chr11_+_83223154	13.533		Rasl10b	RAS-like, family 10, member B
chr7_-_17200285	13.403	NM_172739	Grlf1	glucocorticoid receptor DNA binding factor 1
chr1_-_177422630	13.373	NM_001199003 NM_011880	Rgs7	regulator of G protein signaling 7
chr11_+_68505612	13.288		Myh10	myosin, heavy polypeptide 10, non-muscle
chr2_-_92241282	13.215		Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1
chr14_+_77556622	13.212	NM_172813	Enox1	ecto-NOX disulfide-thiol exchanger 1
chr8_+_14095884	13.153		Dlgap2	discs, large (Drosophila) homolog-associated protein 2
chr1_+_91476810	13.146		Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr5_+_89316245	13.125	NM_001136260 NM_001197147 NM_018760	Slc4a4	solute carrier family 4 (anion exchanger), member 4
chr2_-_25978328	13.024	NM_026495	Nacc2	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chrX_+_5624624	12.982	NM_021431	Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr16_+_94592373	12.929		Ttc3	tetratricopeptide repeat domain 3
chr9_-_75458954	12.928		Tmod2	tropomodulin 2
chr11_+_116780161	12.926	NM_172948	Mgat5b	mannoside acetylglucosaminyltransferase 5, isoenzyme B
chrX_+_20265584	12.899		Cdk16	cyclin-dependent kinase 16
chr14_+_12386043	12.838	NM_008981	Ptprg	protein tyrosine phosphatase, receptor type, G
chr5_-_143084635	12.801		Mmd2	monocyte to macrophage differentiation-associated 2
chr2_+_38206759	12.688	NM_010710	Lhx2	LIM homeobox protein 2
chr5_+_34338625	12.651	NM_001001985	Nat8l	N-acetyltransferase 8-like
chr15_-_93426312	12.649	NM_001033217	Prickle1	prickle homolog 1 (Drosophila)
chr11_+_90110825	12.634		Mmd	monocyte to macrophage differentiation-associated
chrX_-_56387565	12.572	NM_010200	Fgf13	fibroblast growth factor 13
chr12_-_8506790	12.483	NM_007483	Rhob	ras homolog gene family, member B
chr11_-_6375845	12.446	NM_011221	Purb	purine rich element binding protein B
chr19_-_7061958	12.432		Vegfb	vascular endothelial growth factor B

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.96	1.40e-27	GO:0007399	nervous system development
1.49	4.99e-24	GO:0051179	localization
1.55	2.40e-21	GO:0048731	system development
2.06	8.79e-21	GO:0048699	generation of neurons
1.48	2.75e-20	GO:0007275	multicellular organismal development
2.01	2.83e-20	GO:0022008	neurogenesis
1.50	1.16e-19	GO:0048856	anatomical structure development
1.44	6.79e-19	GO:0032502	developmental process
2.59	2.40e-18	GO:0031175	neuron projection development
1.48	3.13e-18	GO:0051234	establishment of localization
2.38	3.16e-18	GO:0048666	neuron development
1.48	4.05e-18	GO:0006810	transport
2.24	3.22e-17	GO:0030030	cell projection organization
2.18	3.84e-17	GO:0030182	neuron differentiation
1.67	4.82e-17	GO:0023051	regulation of signaling
1.67	8.57e-16	GO:0009653	anatomical structure morphogenesis
1.86	2.90e-15	GO:0048468	cell development
2.41	6.28e-15	GO:0019226	transmission of nerve impulse
2.41	6.28e-15	GO:0035637	multicellular organismal signaling
1.41	8.12e-14	GO:0016043	cellular component organization
1.51	9.40e-14	GO:0030154	cell differentiation
1.83	1.13e-13	GO:0051128	regulation of cellular component organization
1.50	1.50e-13	GO:0048869	cellular developmental process
2.55	3.93e-13	GO:0048812	neuron projection morphogenesis
2.08	1.35e-12	GO:0032989	cellular component morphogenesis
1.90	2.11e-12	GO:0007154	cell communication
2.46	4.11e-12	GO:0007268	synaptic transmission
2.57	1.58e-11	GO:0007409	axonogenesis
1.66	1.81e-11	GO:0010646	regulation of cell communication
2.08	2.04e-11	GO:0000902	cell morphogenesis
2.12	2.42e-11	GO:0060284	regulation of cell development
1.62	3.17e-11	GO:0009966	regulation of signal transduction
2.29	3.83e-11	GO:0048858	cell projection morphogenesis
2.28	4.76e-11	GO:0000904	cell morphogenesis involved in differentiation
1.36	5.44e-11	GO:0071840	cellular component organization or biogenesis
1.43	1.01e-10	GO:0071842	cellular component organization at cellular level
2.74	1.03e-10	GO:0042391	regulation of membrane potential
2.24	1.39e-10	GO:0032990	cell part morphogenesis
2.41	3.23e-10	GO:0048667	cell morphogenesis involved in neuron differentiation
1.64	3.65e-10	GO:0032879	regulation of localization
2.10	7.45e-10	GO:0051960	regulation of nervous system development
2.15	1.30e-09	GO:0050767	regulation of neurogenesis
1.45	1.55e-09	GO:0065008	regulation of biological quality
1.90	1.81e-09	GO:0072358	cardiovascular system development
1.90	1.81e-09	GO:0072359	circulatory system development
1.61	2.40e-09	GO:0035556	intracellular signal transduction
2.01	2.43e-09	GO:0007267	cell-cell signaling
1.34	4.28e-09	GO:0048518	positive regulation of biological process
1.40	4.39e-09	GO:0048523	negative regulation of cellular process
1.38	6.10e-09	GO:0048519	negative regulation of biological process
1.36	8.84e-09	GO:0048522	positive regulation of cellular process
1.79	9.17e-09	GO:0007155	cell adhesion
2.22	1.04e-08	GO:0045664	regulation of neuron differentiation
1.78	1.76e-08	GO:0022610	biological adhesion
2.10	2.03e-08	GO:0001944	vasculature development
1.68	3.24e-08	GO:0045595	regulation of cell differentiation
1.58	4.08e-08	GO:0050793	regulation of developmental process
1.37	4.57e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.68	6.60e-08	GO:0051049	regulation of transport
1.44	1.84e-07	GO:0048583	regulation of response to stimulus
1.87	2.73e-07	GO:0055082	cellular chemical homeostasis
1.98	2.90e-07	GO:0007167	enzyme linked receptor protein signaling pathway
1.73	4.11e-07	GO:0016192	vesicle-mediated transport
1.87	6.09e-07	GO:0006873	cellular ion homeostasis
2.43	6.54e-07	GO:0010975	regulation of neuron projection development
1.81	1.32e-06	GO:0050801	ion homeostasis
2.17	1.39e-06	GO:0030029	actin filament-based process
1.43	2.27e-06	GO:0051239	regulation of multicellular organismal process
1.57	2.54e-06	GO:2000026	regulation of multicellular organismal development
1.95	2.84e-06	GO:0007420	brain development
1.70	3.10e-06	GO:0040011	locomotion
1.89	3.53e-06	GO:0016477	cell migration
1.09	3.84e-06	GO:0009987	cellular process
2.48	4.58e-06	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.48	4.58e-06	GO:0022604	regulation of cell morphogenesis
2.24	4.72e-06	GO:0031344	regulation of cell projection organization
1.41	6.14e-06	GO:0065009	regulation of molecular function
1.51	6.28e-06	GO:0006796	phosphate metabolic process
1.51	7.45e-06	GO:0006793	phosphorus metabolic process
2.92	7.46e-06	GO:0010721	negative regulation of cell development
1.72	9.46e-06	GO:0048646	anatomical structure formation involved in morphogenesis
1.38	1.06e-05	GO:0006464	protein modification process
1.85	1.22e-05	GO:0007610	behavior
2.14	1.28e-05	GO:0030036	actin cytoskeleton organization
3.82	1.36e-05	GO:0007269	neurotransmitter secretion
3.82	1.36e-05	GO:0007270	nerve-nerve synaptic transmission
1.78	1.39e-05	GO:0006928	cellular component movement
1.65	1.87e-05	GO:0048878	chemical homeostasis
2.06	2.00e-05	GO:0051056	regulation of small GTPase mediated signal transduction
1.88	2.20e-05	GO:0022603	regulation of anatomical structure morphogenesis
2.12	2.31e-05	GO:0030900	forebrain development
1.49	2.32e-05	GO:0008104	protein localization
3.41	2.36e-05	GO:0050808	synapse organization
1.67	2.40e-05	GO:0071844	cellular component assembly at cellular level
1.86	2.53e-05	GO:0006163	purine nucleotide metabolic process
1.69	3.06e-05	GO:0019725	cellular homeostasis
1.98	3.18e-05	GO:0007264	small GTPase mediated signal transduction
1.98	3.95e-05	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.78	4.11e-05	GO:0023057	negative regulation of signaling
1.97	4.40e-05	GO:0009144	purine nucleoside triphosphate metabolic process
1.77	4.68e-05	GO:0010648	negative regulation of cell communication
1.97	5.48e-05	GO:0009199	ribonucleoside triphosphate metabolic process
1.60	5.98e-05	GO:0019220	regulation of phosphate metabolic process
1.60	5.98e-05	GO:0051174	regulation of phosphorus metabolic process
1.77	6.05e-05	GO:0048870	cell motility
1.77	6.05e-05	GO:0051674	localization of cell
1.94	6.70e-05	GO:0009141	nucleoside triphosphate metabolic process
1.74	6.74e-05	GO:0007417	central nervous system development
1.92	6.89e-05	GO:0001568	blood vessel development
1.43	7.06e-05	GO:0033036	macromolecule localization
2.10	7.67e-05	GO:0051969	regulation of transmission of nerve impulse
1.35	7.76e-05	GO:0048513	organ development
1.80	8.54e-05	GO:0009968	negative regulation of signal transduction
1.95	8.86e-05	GO:0006140	regulation of nucleotide metabolic process
1.86	1.01e-04	GO:0035295	tube development
2.04	1.19e-04	GO:0031644	regulation of neurological system process
1.72	1.24e-04	GO:0007010	cytoskeleton organization
2.03	1.42e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
2.88	1.61e-04	GO:0048167	regulation of synaptic plasticity
2.28	1.81e-04	GO:0042692	muscle cell differentiation
1.42	1.84e-04	GO:0050790	regulation of catalytic activity
2.75	1.85e-04	GO:0050770	regulation of axonogenesis
1.65	1.95e-04	GO:0023056	positive regulation of signaling
2.11	2.16e-04	GO:0050804	regulation of synaptic transmission
1.49	2.18e-04	GO:0009888	tissue development
2.52	2.20e-04	GO:0003001	generation of a signal involved in cell-cell signaling
2.52	2.20e-04	GO:0023061	signal release
1.59	2.21e-04	GO:0042325	regulation of phosphorylation
2.69	2.23e-04	GO:0006836	neurotransmitter transport
1.52	2.60e-04	GO:0045184	establishment of protein localization
1.88	2.63e-04	GO:0009150	purine ribonucleotide metabolic process
1.64	2.67e-04	GO:0010647	positive regulation of cell communication
1.77	2.87e-04	GO:0090066	regulation of anatomical structure size
1.74	2.92e-04	GO:0044057	regulation of system process
1.45	3.46e-04	GO:0051641	cellular localization
2.01	3.66e-04	GO:0006897	endocytosis
2.01	3.66e-04	GO:0010324	membrane invagination
2.91	3.68e-04	GO:0050905	neuromuscular process
2.48	3.70e-04	GO:0051146	striated muscle cell differentiation
1.33	3.76e-04	GO:0043412	macromolecule modification
2.29	4.06e-04	GO:0007626	locomotory behavior
1.20	4.36e-04	GO:0019222	regulation of metabolic process
1.51	5.09e-04	GO:0015031	protein transport
1.95	5.09e-04	GO:0048514	blood vessel morphogenesis
1.99	5.11e-04	GO:0051129	negative regulation of cellular component organization
1.50	5.12e-04	GO:0006811	ion transport
1.65	5.39e-04	GO:0048585	negative regulation of response to stimulus
2.02	5.91e-04	GO:0016337	cell-cell adhesion
1.71	8.19e-04	GO:0072521	purine-containing compound metabolic process
2.34	8.73e-04	GO:0007411	axon guidance
1.82	9.41e-04	GO:0009259	ribonucleotide metabolic process
1.47	1.06e-03	GO:0022607	cellular component assembly
3.46	1.18e-03	GO:0048489	synaptic vesicle transport
2.21	1.18e-03	GO:0030811	regulation of nucleotide catabolic process
2.21	1.18e-03	GO:0033121	regulation of purine nucleotide catabolic process
1.85	1.21e-03	GO:0007507	heart development
1.68	1.23e-03	GO:0016044	cellular membrane organization
1.27	1.29e-03	GO:0044267	cellular protein metabolic process
1.97	1.37e-03	GO:0046578	regulation of Ras protein signal transduction
1.67	1.55e-03	GO:0061024	membrane organization
1.77	1.62e-03	GO:0032535	regulation of cellular component size
3.53	1.66e-03	GO:0035272	exocrine system development
2.72	1.84e-03	GO:0001505	regulation of neurotransmitter levels
3.38	1.85e-03	GO:0048168	regulation of neuronal synaptic plasticity
1.56	1.94e-03	GO:0006812	cation transport
1.20	2.05e-03	GO:0031323	regulation of cellular metabolic process
2.11	2.07e-03	GO:0060537	muscle tissue development
2.27	2.14e-03	GO:0033124	regulation of GTP catabolic process
3.95	2.38e-03	GO:0007431	salivary gland development
3.95	2.38e-03	GO:0030837	negative regulation of actin filament polymerization
1.78	2.39e-03	GO:0045596	negative regulation of cell differentiation
1.60	2.54e-03	GO:0030001	metal ion transport
3.44	2.64e-03	GO:0021954	central nervous system neuron development
1.75	2.95e-03	GO:0009894	regulation of catabolic process
1.45	2.97e-03	GO:0051649	establishment of localization in cell
1.46	3.39e-03	GO:0016310	phosphorylation
1.50	3.50e-03	GO:0006468	protein phosphorylation
1.85	3.61e-03	GO:0061061	muscle structure development
2.03	3.98e-03	GO:0001525	angiogenesis
2.24	4.01e-03	GO:0030324	lung development
1.11	4.12e-03	GO:0050789	regulation of biological process
1.11	4.40e-03	GO:0065007	biological regulation
1.11	4.51e-03	GO:0050794	regulation of cellular process
1.72	4.54e-03	GO:0051130	positive regulation of cellular component organization
1.60	4.65e-03	GO:0009967	positive regulation of signal transduction
2.78	4.80e-03	GO:0055002	striated muscle cell development
2.23	4.95e-03	GO:0043087	regulation of GTPase activity
2.65	5.09e-03	GO:0055001	muscle cell development
1.55	5.09e-03	GO:0001932	regulation of protein phosphorylation
5.73	5.81e-03	GO:0021697	cerebellar cortex formation
1.57	6.06e-03	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
2.21	6.09e-03	GO:0030323	respiratory tube development
2.04	6.13e-03	GO:0051493	regulation of cytoskeleton organization
2.52	6.57e-03	GO:0060485	mesenchyme development
2.61	6.78e-03	GO:0050768	negative regulation of neurogenesis
1.41	7.68e-03	GO:0032268	regulation of cellular protein metabolic process
2.37	8.22e-03	GO:0021953	central nervous system neuron differentiation
1.58	8.43e-03	GO:0006753	nucleoside phosphate metabolic process
1.58	8.43e-03	GO:0009117	nucleotide metabolic process
2.15	9.05e-03	GO:0050890	cognition
3.33	9.23e-03	GO:0048741	skeletal muscle fiber development
1.88	9.37e-03	GO:0001558	regulation of cell growth
1.86	1.01e-02	GO:0032940	secretion by cell
2.46	1.10e-02	GO:0001508	regulation of action potential
1.76	1.13e-02	GO:0030334	regulation of cell migration
2.55	1.18e-02	GO:0001764	neuron migration
1.64	1.37e-02	GO:0051093	negative regulation of developmental process
2.17	1.38e-02	GO:0007611	learning or memory
1.98	1.43e-02	GO:0043062	extracellular structure organization
1.37	1.47e-02	GO:0051246	regulation of protein metabolic process
4.17	1.54e-02	GO:0021795	cerebral cortex cell migration
1.86	1.56e-02	GO:0009207	purine ribonucleoside triphosphate catabolic process
2.08	1.56e-02	GO:0060541	respiratory system development
2.00	1.59e-02	GO:0060627	regulation of vesicle-mediated transport
2.62	1.59e-02	GO:0009142	nucleoside triphosphate biosynthetic process
1.70	1.66e-02	GO:0040012	regulation of locomotion
2.26	1.67e-02	GO:0032956	regulation of actin cytoskeleton organization
1.54	1.68e-02	GO:0051094	positive regulation of developmental process
2.82	1.70e-02	GO:0006754	ATP biosynthetic process
1.45	1.73e-02	GO:0031399	regulation of protein modification process
4.42	1.79e-02	GO:0021696	cerebellar cortex morphogenesis
1.85	1.80e-02	GO:0009203	ribonucleoside triphosphate catabolic process
2.40	1.81e-02	GO:0031589	cell-substrate adhesion
2.66	1.83e-02	GO:0014031	mesenchymal cell development
1.73	1.85e-02	GO:2000145	regulation of cell motility
4.78	1.89e-02	GO:0007416	synapse assembly
1.80	1.97e-02	GO:0006195	purine nucleotide catabolic process
3.30	2.06e-02	GO:0032272	negative regulation of protein polymerization
1.12	2.12e-02	GO:0044237	cellular metabolic process
1.78	2.17e-02	GO:0010740	positive regulation of intracellular protein kinase cascade
3.82	2.18e-02	GO:0007435	salivary gland morphogenesis
1.73	2.29e-02	GO:0034655	nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.73	2.29e-02	GO:0034656	nucleobase, nucleoside and nucleotide catabolic process
1.69	2.30e-02	GO:0046903	secretion
1.60	2.33e-02	GO:0040008	regulation of growth
1.83	2.39e-02	GO:0009146	purine nucleoside triphosphate catabolic process
1.45	2.42e-02	GO:0055085	transmembrane transport
2.02	2.57e-02	GO:0014706	striated muscle tissue development
1.75	2.66e-02	GO:0031329	regulation of cellular catabolic process
3.37	2.99e-02	GO:0021885	forebrain cell migration
1.63	3.12e-02	GO:0051050	positive regulation of transport
3.09	3.12e-02	GO:0021549	cerebellum development
1.82	3.14e-02	GO:0009154	purine ribonucleotide catabolic process
1.60	3.16e-02	GO:0045597	positive regulation of cell differentiation
2.72	3.19e-02	GO:0031345	negative regulation of cell projection organization
2.59	3.24e-02	GO:0009145	purine nucleoside triphosphate biosynthetic process
4.20	3.51e-02	GO:0008038	neuron recognition
3.68	3.70e-02	GO:0021587	cerebellum morphogenesis
1.47	3.81e-02	GO:0012501	programmed cell death
2.18	3.87e-02	GO:0032970	regulation of actin filament-based process
1.67	3.98e-02	GO:0051270	regulation of cellular component movement
1.57	4.15e-02	GO:0060341	regulation of cellular localization
3.45	4.29e-02	GO:0022029	telencephalon cell migration
1.76	4.31e-02	GO:0072523	purine-containing compound catabolic process
2.30	4.60e-02	GO:0034765	regulation of ion transmembrane transport
1.91	4.63e-02	GO:0070838	divalent metal ion transport
1.47	4.67e-02	GO:0009887	organ morphogenesis
2.48	4.70e-02	GO:0007612	learning
1.79	4.71e-02	GO:0009143	nucleoside triphosphate catabolic process
1.72	4.76e-02	GO:0009166	nucleotide catabolic process
1.49	4.77e-02	GO:0009605	response to external stimulus

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.32	1.01e-39	GO:0005737	cytoplasm
1.23	1.57e-37	GO:0005622	intracellular
1.22	1.95e-32	GO:0044424	intracellular part
1.36	2.56e-28	GO:0044444	cytoplasmic part
2.55	4.06e-28	GO:0045202	synapse
2.41	8.87e-28	GO:0043005	neuron projection
1.88	7.85e-23	GO:0042995	cell projection
1.11	2.67e-22	GO:0005623	cell
1.11	2.67e-22	GO:0044464	cell part
1.41	3.44e-21	GO:0071944	cell periphery
1.41	1.06e-20	GO:0005886	plasma membrane
2.57	1.11e-19	GO:0044456	synapse part
1.20	4.29e-19	GO:0043229	intracellular organelle
1.20	1.08e-18	GO:0043226	organelle
2.65	2.23e-18	GO:0030425	dendrite
2.00	4.04e-16	GO:0030054	cell junction
1.55	9.60e-16	GO:0044459	plasma membrane part
2.37	1.09e-14	GO:0043025	neuronal cell body
2.33	1.57e-14	GO:0044297	cell body
1.19	9.30e-14	GO:0016020	membrane
1.64	1.91e-13	GO:0000267	cell fraction
2.14	2.10e-13	GO:0044463	cell projection part
1.71	3.29e-12	GO:0005626	insoluble fraction
1.54	6.04e-12	GO:0005856	cytoskeleton
1.70	1.46e-11	GO:0005624	membrane fraction
1.16	6.88e-10	GO:0043231	intracellular membrane-bounded organelle
1.16	7.19e-10	GO:0043227	membrane-bounded organelle
2.66	7.44e-10	GO:0045211	postsynaptic membrane
2.26	8.01e-10	GO:0030424	axon
3.28	7.57e-09	GO:0030427	site of polarized growth
2.50	7.66e-09	GO:0031252	cell leading edge
1.59	2.43e-08	GO:0044430	cytoskeletal part
1.45	2.56e-08	GO:0005829	cytosol
3.21	5.52e-08	GO:0030426	growth cone
2.64	5.87e-08	GO:0019717	synaptosome
4.20	1.83e-07	GO:0042734	presynaptic membrane
1.29	3.44e-07	GO:0043234	protein complex
3.04	5.65e-07	GO:0014069	postsynaptic density
1.52	1.34e-06	GO:0005794	Golgi apparatus
2.96	1.20e-05	GO:0044309	neuron spine
1.24	1.52e-05	GO:0032991	macromolecular complex
2.93	2.55e-05	GO:0043197	dendritic spine
1.52	3.70e-05	GO:0031982	vesicle
1.53	5.97e-05	GO:0031410	cytoplasmic vesicle
2.16	7.63e-05	GO:0030135	coated vesicle
1.13	1.92e-04	GO:0044425	membrane part
2.20	2.14e-04	GO:0030136	clathrin-coated vesicle
3.23	6.40e-04	GO:0005905	coated pit
1.77	8.36e-04	GO:0044431	Golgi apparatus part
1.24	1.20e-03	GO:0043228	non-membrane-bounded organelle
1.24	1.20e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.17	1.34e-03	GO:0044446	intracellular organelle part
2.39	1.46e-03	GO:0016327	apicolateral plasma membrane
3.58	1.74e-03	GO:0008287	protein serine/threonine phosphatase complex
1.38	1.78e-03	GO:0005783	endoplasmic reticulum
2.14	2.00e-03	GO:0033267	axon part
1.84	2.27e-03	GO:0005911	cell-cell junction
1.17	2.47e-03	GO:0044422	organelle part
1.74	2.64e-03	GO:0015629	actin cytoskeleton
2.32	2.93e-03	GO:0008021	synaptic vesicle
2.43	3.19e-03	GO:0030027	lamellipodium
2.26	3.74e-03	GO:0019898	extrinsic to membrane
1.33	4.69e-03	GO:0031090	organelle membrane
2.51	5.34e-03	GO:0019897	extrinsic to plasma membrane
2.07	7.86e-03	GO:0005912	adherens junction
2.28	8.46e-03	GO:0043296	apical junction complex
1.71	1.10e-02	GO:0005874	microtubule
2.59	1.12e-02	GO:0030117	membrane coat
2.59	1.12e-02	GO:0048475	coated membrane
1.39	1.39e-02	GO:0012505	endomembrane system
1.53	1.53e-02	GO:0005768	endosome
2.82	1.88e-02	GO:0005913	cell-cell adherens junction
4.02	2.20e-02	GO:0008328	ionotropic glutamate receptor complex
1.45	2.34e-02	GO:0015630	microtubule cytoskeleton
1.95	2.48e-02	GO:0070161	anchoring junction
1.40	4.20e-02	GO:0031226	intrinsic to plasma membrane
2.87	4.41e-02	GO:0031594	neuromuscular junction

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.39	1.00e-33	GO:0005515	protein binding
1.22	2.20e-32	GO:0005488	binding
1.93	5.19e-11	GO:0008092	cytoskeletal protein binding
2.00	8.66e-10	GO:0060589	nucleoside-triphosphatase regulator activity
2.00	1.67e-09	GO:0030695	GTPase regulator activity
1.27	6.94e-08	GO:0043169	cation binding
1.80	7.37e-08	GO:0005509	calcium ion binding
1.40	9.11e-08	GO:0032553	ribonucleotide binding
1.27	1.27e-07	GO:0043167	ion binding
1.39	1.33e-07	GO:0032555	purine ribonucleotide binding
1.35	1.53e-07	GO:0000166	nucleotide binding
1.27	1.67e-07	GO:0046872	metal ion binding
2.04	1.69e-07	GO:0003779	actin binding
1.39	2.13e-07	GO:0017076	purine nucleotide binding
1.59	2.48e-07	GO:0030234	enzyme regulator activity
1.39	2.96e-07	GO:0035639	purine ribonucleoside triphosphate binding
2.67	4.09e-07	GO:0005516	calmodulin binding
4.54	8.64e-07	GO:0035254	glutamate receptor binding
1.72	1.43e-06	GO:0019904	protein domain specific binding
2.06	2.24e-06	GO:0005083	small GTPase regulator activity
1.88	2.33e-06	GO:0032403	protein complex binding
1.67	5.54e-06	GO:0004672	protein kinase activity
5.35	6.56e-06	GO:0035255	ionotropic glutamate receptor binding
2.62	1.87e-05	GO:0019838	growth factor binding
1.81	3.77e-05	GO:0019001	guanyl nucleotide binding
1.81	3.77e-05	GO:0032561	guanyl ribonucleotide binding
2.93	4.40e-05	GO:0019199	transmembrane receptor protein kinase activity
1.56	5.86e-05	GO:0015075	ion transmembrane transporter activity
1.83	1.08e-04	GO:0008047	enzyme activator activity
1.47	1.28e-04	GO:0022892	substrate-specific transporter activity
1.50	1.64e-04	GO:0022891	substrate-specific transmembrane transporter activity
1.54	1.95e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.47	2.64e-04	GO:0019899	enzyme binding
1.41	3.34e-04	GO:0005215	transporter activity
1.46	3.88e-04	GO:0022857	transmembrane transporter activity
1.76	3.93e-04	GO:0005525	GTP binding
2.98	4.83e-04	GO:0004714	transmembrane receptor protein tyrosine kinase activity
1.78	6.63e-04	GO:0019900	kinase binding
1.46	8.61e-04	GO:0016301	kinase activity
2.49	9.27e-04	GO:0030165	PDZ domain binding
1.59	1.07e-03	GO:0008324	cation transmembrane transporter activity
1.93	1.49e-03	GO:0005096	GTPase activator activity
2.00	1.69e-03	GO:0005244	voltage-gated ion channel activity
2.00	1.69e-03	GO:0022832	voltage-gated channel activity
1.80	3.72e-03	GO:0019901	protein kinase binding
1.31	3.86e-03	GO:0032559	adenyl ribonucleotide binding
1.90	4.57e-03	GO:0019787	small conjugating protein ligase activity
1.30	5.58e-03	GO:0030554	adenyl nucleotide binding
1.73	6.38e-03	GO:0022836	gated channel activity
1.30	8.65e-03	GO:0005524	ATP binding
1.14	1.12e-02	GO:0003824	catalytic activity
2.09	1.13e-02	GO:0004713	protein tyrosine kinase activity
1.88	1.48e-02	GO:0004842	ubiquitin-protein ligase activity
1.78	1.70e-02	GO:0016881	acid-amino acid ligase activity
2.04	1.94e-02	GO:0022843	voltage-gated cation channel activity
1.34	1.98e-02	GO:0005102	receptor binding
4.25	2.04e-02	GO:0004683	calmodulin-dependent protein kinase activity
1.35	2.81e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups
3.82	2.91e-02	GO:0005520	insulin-like growth factor binding
1.56	4.27e-02	GO:0022838	substrate-specific channel activity
3.66	4.92e-02	GO:0005245	voltage-gated calcium channel activity