Motif ID: MYFfamily.p2

Z-value: 1.973


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
Myf5 17877 myogenic factor 5
Myf6 17878 myogenic factor 6
Myod1 17927 myogenic differentiation 1
Myog 17928 myogenin

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Myf5chr10_-_106922986-0.272.0e-04Click!
Myod1chr7_+_53631843-0.154.5e-02Click!
Myogchr1_+_136186579-0.101.9e-01Click!
Myf6chr10_-_106931783-0.064.0e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_119510890 63.551 NM_138742
Nap1l3
nucleosome assembly protein 1-like 3
chr8_-_9771020 52.359 NM_173446
Fam155a
family with sequence similarity 155, member A
chr9_-_112088452 40.676 NM_001177618
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr2_+_83652846 35.894 NM_175514
Fam171b
family with sequence similarity 171, member B
chr4_+_104829951 30.944 NM_080555
Ppap2b
phosphatidic acid phosphatase type 2B
chr18_+_45719732 29.479 NM_080465
Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr4_+_104829963 28.668 Ppap2b
phosphatidic acid phosphatase type 2B
chr9_+_75473524 27.256 NM_027309
Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr2_+_48805027 26.314 NM_029924
Mbd5
methyl-CpG binding domain protein 5
chr12_-_73509668 25.503 Rtn1
reticulon 1
chr6_-_77929543 24.716 Ctnna2
catenin (cadherin associated protein), alpha 2
chr2_+_157387284 23.863 Nnat
neuronatin
chr4_+_104830022 23.681 Ppap2b
phosphatidic acid phosphatase type 2B
chr18_+_45719464 23.458 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr6_-_77929685 23.375 Ctnna2
catenin (cadherin associated protein), alpha 2
chr17_+_35373506 23.325 NM_023179
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr12_-_71448600 23.250 NM_001110202
NM_001110203
NM_053167
Trim9


tripartite motif-containing 9


chr9_+_27598853 23.020 NM_177906
Opcml
opioid binding protein/cell adhesion molecule-like
chr6_-_126690651 22.792 NM_013568
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr12_-_73509537 22.481 Rtn1
reticulon 1
chr18_+_45719101 21.411 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr18_-_43058544 20.940 NM_027531
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr13_+_64263131 20.486 NM_019986
Habp4
hyaluronic acid binding protein 4
chr16_-_67621054 19.536 NM_001145977
NM_178721
Cadm2

cell adhesion molecule 2

chr13_-_69877709 19.105 Ube2ql1
ubiquitin-conjugating enzyme E2Q family-like 1
chr1_-_125942073 18.631 NM_199021
Dpp10
dipeptidylpeptidase 10
chrX_-_131745187 18.392 NM_025355
Tceal6
transcription elongation factor A (SII)-like 6
chr16_+_6349108 17.803 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_84692352 17.735 Dner
delta/notch-like EGF-related receptor
chrX_-_100381973 17.613 NM_008671
Nap1l2
nucleosome assembly protein 1-like 2
chr6_-_77929660 17.608 NM_001109764
NM_009819
NM_145732
Ctnna2


catenin (cadherin associated protein), alpha 2


chr13_+_58909236 17.382 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr12_-_71448300 17.241 Trim9
tripartite motif-containing 9
chr18_-_43847367 17.162 NM_001163637
Jakmip2
janus kinase and microtubule interacting protein 2
chr16_-_28753276 17.075 NM_010199
Fgf12
fibroblast growth factor 12
chr13_+_58909648 16.251 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr5_-_38550627 15.934 NM_010942
Nsg1
neuron specific gene family member 1
chr6_-_23789048 15.754 Cadps2
Ca2+-dependent activator protein for secretion 2
chr12_-_73509925 15.379 NM_153457
Rtn1
reticulon 1
chr8_+_128519295 15.336 Kcnk1
potassium channel, subfamily K, member 1
chr13_-_78337844 15.225 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr4_+_104829867 15.153 Ppap2b
phosphatidic acid phosphatase type 2B
chr13_+_58909254 14.694 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr9_+_45178267 14.631 NM_022004
Fxyd6
FXYD domain-containing ion transport regulator 6
chr7_+_138079669 14.549 NM_019564
Htra1
HtrA serine peptidase 1
chr2_-_84614976 14.544 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr9_+_45178485 14.482 Fxyd6
FXYD domain-containing ion transport regulator 6
chr16_-_4419586 14.292 NM_009624
Adcy9
adenylate cyclase 9
chr9_+_45178521 14.188 Fxyd6
FXYD domain-containing ion transport regulator 6
chr8_+_128519001 14.186 NM_008430
Kcnk1
potassium channel, subfamily K, member 1
chr11_+_101107726 14.165 Ramp2
receptor (calcitonin) activity modifying protein 2
chr14_-_68742863 13.928 Nefm
neurofilament, medium polypeptide
chr11_+_101107635 13.731 NM_019444
Ramp2
receptor (calcitonin) activity modifying protein 2
chr16_+_91270319 13.715 Olig1
oligodendrocyte transcription factor 1
chr17_+_24641034 13.593 Caskin1
CASK interacting protein 1
chr13_+_58909168 13.164 NM_001025074
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr16_+_91270009 13.069 NM_016968
Olig1
oligodendrocyte transcription factor 1
chr12_-_46175433 13.064 NM_144552
Stxbp6
syntaxin binding protein 6 (amisyn)
chr2_+_61884596 12.826 NM_033552
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr2_-_115890247 12.764 NM_001159569
NM_001159570
Meis2

Meis homeobox 2

chr8_-_73011217 12.708 NM_182991
Tmem59l
transmembrane protein 59-like
chr16_-_28753298 12.691 Fgf12
fibroblast growth factor 12
chr9_-_97933533 12.539 NM_022319
Clstn2
calsyntenin 2
chr7_+_80885223 12.482 Fam174b
family with sequence similarity 174, member B
chrX_+_20281028 12.360 NM_145628
Usp11
ubiquitin specific peptidase 11
chrX_+_155897136 12.310 Mtap7d2
MAP7 domain containing 2
chr12_+_109572514 12.309 NM_010010
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr14_-_124026357 12.204 NM_177393
Nalcn
sodium leak channel, non-selective
chr10_+_62849310 12.166 NM_013888
Dnajc12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr13_+_58909632 12.098 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr1_+_164569335 12.083 Myoc
myocilin
chr16_-_45724720 11.969 Tagln3
transgelin 3
chr6_-_136824217 11.703 Mgp
matrix Gla protein
chr1_-_82287990 11.640 NM_010570
Irs1
insulin receptor substrate 1
chr7_-_134164627 11.604 NM_001102563
Prrt2
proline-rich transmembrane protein 2
chrX_+_71550562 11.590 Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr5_-_77837037 11.532 NM_001159518
NM_008048
Igfbp7

insulin-like growth factor binding protein 7

chr11_-_4847968 11.528 NM_010904
Nefh
neurofilament, heavy polypeptide
chr12_+_16660521 11.518 Ntsr2
neurotensin receptor 2
chr15_-_37389073 11.370 NM_001170867
NM_001170868
Ncald

neurocalcin delta

chr8_+_96676506 11.325 NM_013603
Mt3
metallothionein 3
chr8_-_87461251 11.316 NM_019945
Mast1
microtubule associated serine/threonine kinase 1
chr16_-_45724422 11.270 NM_019754
Tagln3
transgelin 3
chr5_-_77836974 11.193 Igfbp7
insulin-like growth factor binding protein 7
chr6_-_113991945 11.125 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr6_+_118016385 11.006 NM_027526
Rasgef1a
RasGEF domain family, member 1A
chr14_-_55531726 10.900 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr3_-_57651409 10.808 Pfn2
profilin 2
chr12_+_16660245 10.777 NM_008747
Ntsr2
neurotensin receptor 2
chr6_-_77929575 10.773 Ctnna2
catenin (cadherin associated protein), alpha 2
chr16_+_41532938 10.763 Lsamp
limbic system-associated membrane protein
chr10_+_115738429 10.653 NM_029928
Ptprb
protein tyrosine phosphatase, receptor type, B
chr15_-_63891810 10.405 NM_144846
Fam49b
family with sequence similarity 49, member B
chr1_+_184695026 10.343 NM_144796
Susd4
sushi domain containing 4
chrX_+_155897056 10.337 Mtap7d2
MAP7 domain containing 2
chr14_-_80061976 10.156 NM_010701
Lect1
leukocyte cell derived chemotaxin 1
chr3_-_57651621 9.983 NM_019410
Pfn2
profilin 2
chr4_+_42929523 9.973 N28178
expressed sequence N28178
chr6_+_88775664 9.940 Mgll
monoglyceride lipase
chr7_+_80885175 9.861 NM_001162532
Fam174b
family with sequence similarity 174, member B
chr6_+_83087016 9.770 NM_009106
NM_133641
Rtkn

rhotekin

chr17_-_25036364 9.756 Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3
chr8_-_113783097 9.729 NM_009149
Glg1
golgi apparatus protein 1
chr2_-_156817751 9.716 NM_013865
NM_180956
Ndrg3

N-myc downstream regulated gene 3

chr3_+_90346956 9.594 S100a16
S100 calcium binding protein A16
chr7_+_25266986 9.575 NM_153112
Cadm4
cell adhesion molecule 4
chr12_+_117724182 9.520 NM_011215
Ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr7_-_31912022 9.499 Scn1b
sodium channel, voltage-gated, type I, beta
chr6_-_92484838 9.422 NM_001134459
Prickle2
prickle homolog 2 (Drosophila)
chr2_-_84614960 9.411 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr7_-_134164487 9.342 Prrt2
proline-rich transmembrane protein 2
chr8_+_46744023 9.315 Sorbs2
sorbin and SH3 domain containing 2
chr4_-_133054355 9.310 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr19_+_4855178 9.287 Ctsf
cathepsin F
chr18_+_35020867 9.277 Egr1
early growth response 1
chr7_+_134094045 9.226 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr10_-_42893894 9.194 Sobp
sine oculis-binding protein homolog (Drosophila)
chr6_-_82889694 9.130 NM_001113481
NM_011350
Sema4f

sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain

chr6_+_107479719 9.112 NM_008516
Lrrn1
leucine rich repeat protein 1, neuronal
chr8_-_75877407 9.112 Large
like-glycosyltransferase
chr7_+_3303657 8.990 NM_011102
Prkcc
protein kinase C, gamma
chr13_-_69878721 8.883 NM_001145162
Ube2ql1
ubiquitin-conjugating enzyme E2Q family-like 1
chr6_-_23789259 8.882 NM_153163
Cadps2
Ca2+-dependent activator protein for secretion 2
chr1_+_11404185 8.847 NM_001160369
NM_001160370
NM_001160371
NM_177173
A830018L16Rik



RIKEN cDNA A830018L16 gene



chr19_-_38199291 8.827 NM_011255
Rbp4
retinol binding protein 4, plasma
chr1_+_66221851 8.826 NM_001039934
NM_008632
Mtap2

microtubule-associated protein 2

chr1_+_160292665 8.796 Astn1
astrotactin 1
chr1_-_166388431 8.766 NM_009721
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr8_-_87461220 8.760 Mast1
microtubule associated serine/threonine kinase 1
chr16_+_41533317 8.724 NM_175548
Lsamp
limbic system-associated membrane protein
chr3_+_156224757 8.720 NM_001039094
NM_177274
Negr1

neuronal growth regulator 1

chr1_-_166387998 8.689 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_50984361 8.628 NM_019790
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chrX_+_50911075 8.624 NM_028375
Cxx1c
CAAX box 1 homolog C (human)
chrX_+_133200913 8.562 NM_001029978
Tceal3
transcription elongation factor A (SII)-like 3
chr7_-_31911884 8.549 NM_011322
Scn1b
sodium channel, voltage-gated, type I, beta
chr1_+_72871060 8.441 NM_008342
Igfbp2
insulin-like growth factor binding protein 2
chr15_-_91403685 8.421 NM_001033633
Slc2a13
solute carrier family 2 (facilitated glucose transporter), member 13
chr2_-_71384748 8.404 NM_010054
Dlx2
distal-less homeobox 2
chr2_+_119625463 8.376 Tyro3
TYRO3 protein tyrosine kinase 3
chr19_+_6427922 8.316 NM_020253
Nrxn2
neurexin II
chr15_+_34167780 8.197 NM_033521
Laptm4b
lysosomal-associated protein transmembrane 4B
chr14_-_80061875 8.176 Lect1
leukocyte cell derived chemotaxin 1
chr15_+_38908403 8.174 NM_026778
Cthrc1
collagen triple helix repeat containing 1
chr7_+_129432810 8.124 Prkcb
protein kinase C, beta
chr7_-_31911754 8.036 Scn1b
sodium channel, voltage-gated, type I, beta
chr16_-_4419805 8.019 Adcy9
adenylate cyclase 9
chr10_-_42894259 8.003 NM_175407
Sobp
sine oculis-binding protein homolog (Drosophila)
chr18_-_16967100 8.002 Cdh2
cadherin 2
chr7_+_129432585 7.987 NM_008855
Prkcb
protein kinase C, beta
chr6_+_117961386 7.970 Rasgef1a
RasGEF domain family, member 1A
chr1_-_175297624 7.959 Cadm3
cell adhesion molecule 3
chr18_-_43059156 7.909 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr1_-_175297778 7.907 NM_053199
Cadm3
cell adhesion molecule 3
chrX_-_50973482 7.860 NM_001018063
Cxx1b
CAAX box 1 homolog B (human)
chrX_-_100381703 7.709 Nap1l2
nucleosome assembly protein 1-like 2
chr9_-_97933599 7.704 Clstn2
calsyntenin 2
chr4_+_129662284 7.702 NM_173071
Bai2
brain-specific angiogenesis inhibitor 2
chr13_-_12199109 7.644 NM_023868
Ryr2
ryanodine receptor 2, cardiac
chr4_-_147412872 7.617 NM_011929
Clcn6
chloride channel 6
chr14_+_66587319 7.614 NM_013492
Clu
clusterin
chr16_-_20621287 7.593 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr4_+_129662110 7.539 Bai2
brain-specific angiogenesis inhibitor 2
chr6_-_82889660 7.393 Sema4f
sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
chr19_-_38199036 7.378 Rbp4
retinol binding protein 4, plasma
chr9_-_52487410 7.356 NM_178906
AI593442
expressed sequence AI593442
chrX_+_71550301 7.355 NM_010273
Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr2_-_23904343 7.325 Hnmt
histamine N-methyltransferase
chr16_+_17276720 7.323 Tmem191c
transmembrane protein 191C
chr9_-_58884114 7.281 NM_001042752
NM_008684
Neo1

neogenin

chr2_-_5635517 7.266 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr19_-_40525876 7.191 NM_001034962
NM_001034963
Sorbs1

sorbin and SH3 domain containing 1

chr7_-_31836457 7.187 NM_022007
Fxyd7
FXYD domain-containing ion transport regulator 7
chrX_+_71550669 7.169 Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr13_-_78338131 7.160 NM_010151
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr18_+_57292743 7.146 NM_001001979
Megf10
multiple EGF-like-domains 10
chr19_-_38199267 7.094 Rbp4
retinol binding protein 4, plasma
chr17_-_27650285 7.076 Grm4
glutamate receptor, metabotropic 4
chr10_+_81038028 7.063 NM_019725
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr6_+_125095236 7.057 NM_178787
NM_001039669
Iffo1

intermediate filament family orphan 1

chr4_-_147412919 7.045 Clcn6
chloride channel 6
chr9_+_110147867 7.029 Cspg5
chondroitin sulfate proteoglycan 5
chr15_+_39491073 6.929 Rims2
regulating synaptic membrane exocytosis 2
chr9_+_75162059 6.897 Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr15_+_54402988 6.892 Mal2
mal, T-cell differentiation protein 2
chr2_-_113669243 6.836 NM_009162
Scg5
secretogranin V
chr1_-_84692750 6.801 NM_152915
Dner
delta/notch-like EGF-related receptor
chr8_-_107995252 6.766 Tppp3
tubulin polymerization-promoting protein family member 3
chr7_-_74904546 6.726 NM_183312
NM_201639
NM_207663
Synm


synemin, intermediate filament protein


chr2_+_119625249 6.704 NM_019392
Tyro3
TYRO3 protein tyrosine kinase 3
chr18_+_37974732 6.688 NM_033582
Pcdhgc4
protocadherin gamma subfamily C, 4
chrX_-_133403050 6.670 NM_176971
Rab9b
RAB9B, member RAS oncogene family
chr2_-_113669229 6.645 Scg5
secretogranin V
chr2_-_12932442 6.644 NM_153155
C1ql3
C1q-like 3
chr11_+_3414884 6.635 Selm
selenoprotein M
chr12_+_70298163 6.613 9330151L19Rik
RIKEN cDNA 9330151L19 gene
chr14_+_34736806 6.600 Gdf10
growth differentiation factor 10
chr7_+_106415956 6.548 NM_001048167
NM_010837
Mtap6

microtubule-associated protein 6

chr11_+_3414792 6.543 Selm
selenoprotein M
chr5_-_133019167 6.528 Auts2
autism susceptibility candidate 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.72 1.70e-14 GO:0007399 nervous system development
1.38 6.02e-13 GO:0051179 localization
1.73 8.23e-13 GO:0032879 regulation of localization
1.61 8.37e-13 GO:0023051 regulation of signaling
1.41 4.06e-12 GO:0051234 establishment of localization
1.40 1.63e-11 GO:0006810 transport
1.43 1.81e-11 GO:0048731 system development
1.81 2.90e-11 GO:0048699 generation of neurons
1.75 3.01e-10 GO:0022008 neurogenesis
1.37 7.14e-10 GO:0048856 anatomical structure development
2.17 2.32e-09 GO:0019226 transmission of nerve impulse
2.17 2.32e-09 GO:0035637 multicellular organismal signaling
1.75 4.45e-09 GO:0051049 regulation of transport
1.61 4.84e-09 GO:0010646 regulation of cell communication
1.33 2.83e-08 GO:0007275 multicellular organismal development
2.25 5.30e-08 GO:0007268 synaptic transmission
2.56 9.02e-08 GO:0010975 regulation of neuron projection development
1.66 1.20e-07 GO:0051128 regulation of cellular component organization
1.43 1.23e-07 GO:0065008 regulation of biological quality
2.19 1.33e-07 GO:0045664 regulation of neuron differentiation
2.07 2.11e-07 GO:0031175 neuron projection development
1.30 2.25e-07 GO:0032502 developmental process
1.86 2.72e-07 GO:0030030 cell projection organization
1.75 3.55e-07 GO:0007155 cell adhesion
1.46 3.69e-07 GO:0051239 regulation of multicellular organismal process
1.91 5.78e-07 GO:0048666 neuron development
1.73 6.35e-07 GO:0022610 biological adhesion
1.31 6.36e-07 GO:0016043 cellular component organization
1.95 8.83e-07 GO:0007610 behavior
1.79 1.19e-06 GO:0030182 neuron differentiation
2.32 1.87e-06 GO:0031344 regulation of cell projection organization
1.86 2.09e-06 GO:0060341 regulation of cellular localization
1.99 2.45e-06 GO:0051046 regulation of secretion
1.88 4.04e-06 GO:0060284 regulation of cell development
1.97 5.83e-06 GO:0050767 regulation of neurogenesis
1.70 9.33e-06 GO:0006812 cation transport
1.59 9.93e-06 GO:0006811 ion transport
1.84 1.55e-05 GO:0007267 cell-cell signaling
1.34 2.06e-05 GO:0071842 cellular component organization at cellular level
1.87 2.27e-05 GO:0051960 regulation of nervous system development
1.46 2.32e-05 GO:0009966 regulation of signal transduction
1.27 3.00e-05 GO:0071840 cellular component organization or biogenesis
2.11 4.50e-05 GO:0031644 regulation of neurological system process
1.72 5.39e-05 GO:0030001 metal ion transport
1.71 5.90e-05 GO:0072358 cardiovascular system development
1.71 5.90e-05 GO:0072359 circulatory system development
2.06 6.48e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
2.04 6.48e-05 GO:0048812 neuron projection morphogenesis
2.11 7.38e-05 GO:0007409 axonogenesis
2.14 8.45e-05 GO:0051969 regulation of transmission of nerve impulse
1.92 9.38e-05 GO:0000904 cell morphogenesis involved in differentiation
2.18 1.01e-04 GO:0050804 regulation of synaptic transmission
1.47 1.64e-04 GO:0050793 regulation of developmental process
2.22 1.83e-04 GO:0043062 extracellular structure organization
1.33 1.99e-04 GO:0030154 cell differentiation
1.51 2.63e-04 GO:2000026 regulation of multicellular organismal development
1.36 2.74e-04 GO:0048583 regulation of response to stimulus
2.33 2.76e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.33 2.76e-04 GO:0022604 regulation of cell morphogenesis
1.54 2.95e-04 GO:0045595 regulation of cell differentiation
1.61 3.28e-04 GO:0016192 vesicle-mediated transport
3.81 4.51e-04 GO:0010464 regulation of mesenchymal cell proliferation
1.31 5.78e-04 GO:0048869 cellular developmental process
1.27 6.25e-04 GO:0048522 positive regulation of cellular process
1.73 9.68e-04 GO:0044057 regulation of system process
3.47 1.25e-03 GO:0050773 regulation of dendrite development
1.83 1.34e-03 GO:0034220 ion transmembrane transport
1.28 1.58e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.24 1.68e-03 GO:0048518 positive regulation of biological process
1.82 1.94e-03 GO:0048858 cell projection morphogenesis
2.98 2.08e-03 GO:0070588 calcium ion transmembrane transport
1.55 2.16e-03 GO:0007154 cell communication
1.78 4.11e-03 GO:0032990 cell part morphogenesis
1.72 4.56e-03 GO:0006163 purine nucleotide metabolic process
1.79 4.63e-03 GO:0015672 monovalent inorganic cation transport
1.35 5.90e-03 GO:0009653 anatomical structure morphogenesis
2.21 6.98e-03 GO:0050890 cognition
1.45 8.28e-03 GO:0048468 cell development
1.86 8.54e-03 GO:0006195 purine nucleotide catabolic process
1.85 8.74e-03 GO:0072523 purine-containing compound catabolic process
1.71 9.22e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.77 9.54e-03 GO:0046700 heterocycle catabolic process
3.66 9.69e-03 GO:0048814 regulation of dendrite morphogenesis
1.63 9.86e-03 GO:0000902 cell morphogenesis
2.76 9.92e-03 GO:0017157 regulation of exocytosis
2.53 1.02e-02 GO:0050770 regulation of axonogenesis
2.04 1.11e-02 GO:0042391 regulation of membrane potential
2.22 1.14e-02 GO:0007611 learning or memory
1.73 1.34e-02 GO:0001944 vasculature development
3.55 1.54e-02 GO:0046928 regulation of neurotransmitter secretion
1.84 1.63e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.76 1.73e-02 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.76 1.73e-02 GO:0034656 nucleobase, nucleoside and nucleotide catabolic process
1.24 1.88e-02 GO:0048519 negative regulation of biological process
1.64 1.89e-02 GO:0072521 purine-containing compound metabolic process
2.44 2.10e-02 GO:0031589 cell-substrate adhesion
1.74 2.19e-02 GO:0001568 blood vessel development
3.45 2.38e-02 GO:0002053 positive regulation of mesenchymal cell proliferation
1.57 2.96e-02 GO:0032989 cellular component morphogenesis
2.54 3.17e-02 GO:0001505 regulation of neurotransmitter levels
3.11 3.19e-02 GO:0007269 neurotransmitter secretion
1.57 3.23e-02 GO:0050801 ion homeostasis
1.65 3.27e-02 GO:0051050 positive regulation of transport
2.05 3.28e-02 GO:0006813 potassium ion transport
1.84 3.33e-02 GO:0009154 purine ribonucleotide catabolic process
1.71 3.43e-02 GO:0044270 cellular nitrogen compound catabolic process
1.73 3.49e-02 GO:0009150 purine ribonucleotide metabolic process
1.30 3.64e-02 GO:0065009 regulation of molecular function
1.37 3.75e-02 GO:0035556 intracellular signal transduction
1.75 3.99e-02 GO:0009144 purine nucleoside triphosphate metabolic process
1.75 4.00e-02 GO:0009166 nucleotide catabolic process
1.75 4.00e-02 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.64 4.53e-02 GO:0008285 negative regulation of cell proliferation
2.14 4.78e-02 GO:0007411 axon guidance
1.72 5.00e-02 GO:0009141 nucleoside triphosphate metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.32 5.33e-23 GO:0043005 neuron projection
2.36 1.01e-20 GO:0045202 synapse
1.86 2.32e-20 GO:0042995 cell projection
2.56 3.23e-18 GO:0044456 synapse part
1.36 2.89e-15 GO:0071944 cell periphery
1.36 1.06e-14 GO:0005886 plasma membrane
1.79 3.11e-14 GO:0005626 insoluble fraction
1.79 8.41e-14 GO:0005624 membrane fraction
1.67 1.54e-13 GO:0000267 cell fraction
1.26 2.42e-13 GO:0044444 cytoplasmic part
1.19 8.55e-13 GO:0005737 cytoplasm
2.37 5.65e-12 GO:0030425 dendrite
2.04 2.11e-10 GO:0044463 cell projection part
2.32 4.95e-10 GO:0030424 axon
2.17 5.32e-10 GO:0031012 extracellular matrix
2.90 6.16e-10 GO:0019717 synaptosome
1.63 3.32e-09 GO:0005794 Golgi apparatus
2.15 2.00e-08 GO:0005578 proteinaceous extracellular matrix
1.15 3.98e-08 GO:0016020 membrane
2.05 5.18e-08 GO:0043025 neuronal cell body
2.00 1.15e-07 GO:0044297 cell body
1.40 1.57e-07 GO:0044459 plasma membrane part
2.68 1.60e-07 GO:0033267 axon part
1.54 2.04e-07 GO:0005783 endoplasmic reticulum
1.56 2.72e-07 GO:0044421 extracellular region part
2.00 1.39e-06 GO:0048471 perinuclear region of cytoplasm
2.61 5.69e-06 GO:0044420 extracellular matrix part
2.25 1.18e-05 GO:0034702 ion channel complex
1.10 1.19e-05 GO:0005622 intracellular
2.31 5.07e-05 GO:0030136 clathrin-coated vesicle
1.52 1.19e-04 GO:0031982 vesicle
2.18 1.21e-04 GO:0030135 coated vesicle
1.87 1.28e-04 GO:0044431 Golgi apparatus part
2.20 1.28e-04 GO:0045211 postsynaptic membrane
2.87 1.49e-04 GO:0043197 dendritic spine
1.09 2.66e-04 GO:0044424 intracellular part
2.79 2.73e-04 GO:0044309 neuron spine
2.52 3.07e-04 GO:0008021 synaptic vesicle
1.30 5.13e-04 GO:0005576 extracellular region
2.68 6.46e-04 GO:0043679 axon terminus
4.60 6.60e-04 GO:0034704 calcium channel complex
1.53 7.76e-04 GO:0030054 cell junction
2.59 9.09e-04 GO:0030427 site of polarized growth
2.59 9.09e-04 GO:0044306 neuron projection terminus
2.40 1.00e-03 GO:0034703 cation channel complex
1.56 1.09e-03 GO:0031988 membrane-bounded vesicle
1.49 1.10e-03 GO:0031410 cytoplasmic vesicle
2.58 1.44e-03 GO:0030426 growth cone
2.52 2.40e-03 GO:0014069 postsynaptic density
1.46 2.62e-03 GO:0005615 extracellular space
1.73 3.22e-03 GO:0044432 endoplasmic reticulum part
1.54 4.77e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
2.97 9.44e-03 GO:0043195 terminal button
3.71 1.19e-02 GO:0005581 collagen
1.05 1.22e-02 GO:0005623 cell
1.05 1.22e-02 GO:0044464 cell part
1.40 1.50e-02 GO:0012505 endomembrane system
5.63 1.94e-02 GO:0060053 neurofilament cytoskeleton
1.11 2.27e-02 GO:0044425 membrane part
2.48 2.43e-02 GO:0031227 intrinsic to endoplasmic reticulum membrane
3.13 2.65e-02 GO:0005795 Golgi stack
2.28 4.67e-02 GO:0005604 basement membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.26 7.46e-14 GO:0005515 protein binding
1.13 2.19e-10 GO:0005488 binding
1.89 2.61e-09 GO:0005509 calcium ion binding
2.24 2.73e-08 GO:0005261 cation channel activity
1.98 7.21e-08 GO:0005216 ion channel activity
1.94 2.42e-07 GO:0022838 substrate-specific channel activity
1.81 3.41e-07 GO:0008324 cation transmembrane transporter activity
1.68 3.61e-07 GO:0015075 ion transmembrane transporter activity
2.08 5.59e-07 GO:0022836 gated channel activity
1.88 1.35e-06 GO:0015267 channel activity
1.88 1.55e-06 GO:0022803 passive transmembrane transporter activity
1.59 3.47e-06 GO:0022891 substrate-specific transmembrane transporter activity
1.54 6.46e-06 GO:0022892 substrate-specific transporter activity
1.86 1.11e-05 GO:0032403 protein complex binding
1.48 1.31e-05 GO:0005215 transporter activity
1.53 2.38e-05 GO:0022857 transmembrane transporter activity
1.75 9.88e-05 GO:0060589 nucleoside-triphosphatase regulator activity
2.42 1.46e-04 GO:0005516 calmodulin binding
1.74 2.01e-04 GO:0030695 GTPase regulator activity
1.49 2.58e-04 GO:0030234 enzyme regulator activity
2.10 3.88e-04 GO:0005244 voltage-gated ion channel activity
2.10 3.88e-04 GO:0022832 voltage-gated channel activity
1.21 6.41e-04 GO:0043167 ion binding
2.45 7.06e-04 GO:0019838 growth factor binding
1.21 7.14e-04 GO:0043169 cation binding
3.00 8.57e-04 GO:0004714 transmembrane receptor protein tyrosine kinase activity
2.76 1.02e-03 GO:0019199 transmembrane receptor protein kinase activity
1.20 1.58e-03 GO:0046872 metal ion binding
2.21 2.33e-03 GO:0022843 voltage-gated cation channel activity
1.57 2.42e-03 GO:0008092 cytoskeletal protein binding
2.06 5.65e-03 GO:0001871 pattern binding
2.06 5.65e-03 GO:0030247 polysaccharide binding
2.13 5.93e-03 GO:0005539 glycosaminoglycan binding
1.79 8.16e-03 GO:0005083 small GTPase regulator activity
2.57 1.02e-02 GO:0005262 calcium channel activity
1.35 2.57e-02 GO:0005102 receptor binding
2.18 2.80e-02 GO:0015276 ligand-gated ion channel activity
2.18 2.80e-02 GO:0022834 ligand-gated channel activity
2.08 3.26e-02 GO:0005267 potassium channel activity
1.64 4.03e-02 GO:0008047 enzyme activator activity