• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: NFE2L1.p2

Z-value: 2.057

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_-_126646303	37.267	NM_001034168	Ank2	ankyrin 2, brain
chr9_-_66880619	31.593		Tpm1	tropomyosin 1, alpha
chr8_-_126417352	29.156		Acta1	actin, alpha 1, skeletal muscle
chr19_+_5492584	26.411
chr11_+_78137699	22.056	NM_009657	Aldoc	aldolase C, fructose-bisphosphate
chr3_+_67868723	19.791	NM_001113420 NM_001113421	Schip1	schwannomin interacting protein 1
chr5_+_136363769	19.770	NM_013560	Hspb1	heat shock protein 1
chr4_-_126427788	19.111		Ncdn	neurochondrin
chr5_+_136363810	18.653		Hspb1	heat shock protein 1
chr4_+_103236110	18.261
chr1_-_71686889	18.241		Fn1	fibronectin 1
chr18_+_36526187	18.139		0610010O12Rik	RIKEN cDNA 0610010O12 gene
chr6_-_125112509	17.492		Gapdh Gm5523 Gm10481	glyceraldehyde-3-phosphate dehydrogenase glyceraldehyde-3-phosphate dehydrogenase pseudogene glyceraldehyde-3-phosphate dehydrogenase pseudogene
chr4_+_138012860	17.251		Camk2n1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr5_+_136363914	16.920		Hspb1	heat shock protein 1
chr5_+_104868321	16.858		Spp1	secreted phosphoprotein 1
chrX_-_22797942	16.741		Klhl13	kelch-like 13 (Drosophila)
chr19_-_10175969	16.517		Fads2	fatty acid desaturase 2
chr1_-_166368439	16.415		Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_-_102988596	16.194
chr5_+_143734622	15.974
chr12_+_30687597	15.948		Pxdn	peroxidasin homolog (Drosophila)
chr6_+_113442698	15.616
chr15_-_88991213	15.311		Plxnb2	plexin B2
chr4_-_82151004	14.684		Nfib	nuclear factor I/B
chr18_+_38611212	14.403
chr4_-_82150687	14.294		Nfib	nuclear factor I/B
chr17_+_44090222	14.188		Rcan2	regulator of calcineurin 2
chr15_+_12251563	13.612		Golph3	golgi phosphoprotein 3
chr15_-_75901305	13.560		Puf60	poly-U binding splicing factor 60
chr5_-_136384495	13.111
chr2_-_64860728	13.037	NM_016719	Grb14	growth factor receptor bound protein 14
chr16_-_20621287	12.879	NM_028420	Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2
chr1_-_82232392	12.668		Irs1	insulin receptor substrate 1
chr9_+_120864938	12.664		Ctnnb1	catenin (cadherin associated protein), beta 1
chr11_+_75570397	12.634		Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr14_+_28689289	12.609		Erc2	ELKS/RAB6-interacting/CAST family member 2
chr9_+_120860017	12.504		Ctnnb1	catenin (cadherin associated protein), beta 1
chrX_+_136145321	12.453		Rnf128	ring finger protein 128
chr14_-_94287950	12.430	NM_001081377	Pcdh9	protocadherin 9
chr16_+_7409879	12.394		Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_-_41596638	12.339	NM_011135	Cnot7	CCR4-NOT transcription complex, subunit 7
chr16_+_7069971	12.237		Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_137063881	12.123		Gpr37l1	G protein-coupled receptor 37-like 1
chr9_-_66881744	12.073		Tpm1	tropomyosin 1, alpha
chr10_+_40657980	11.883		Wasf1	WASP family 1
chr8_+_120807621	11.872	NM_019707	Cdh13	cadherin 13
chr17_+_44090341	11.831		Rcan2	regulator of calcineurin 2
chr12_+_73885063	11.787		Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform
chr18_-_25637786	11.706		Celf4	CUGBP, Elav-like family member 4
chr19_-_7292086	11.598	NM_007750	Cox8a	cytochrome c oxidase, subunit VIIIa
chr17_-_13133166	11.592	NM_153151	Acat3	acetyl-Coenzyme A acetyltransferase 3
chr19_+_25484006	11.461		Kank1	KN motif and ankyrin repeat domains 1
chr4_+_62050088	11.230		Slc31a1	solute carrier family 31, member 1
chr8_+_120807674	11.178		Cdh13	cadherin 13
chr17_+_44090139	11.050	NM_030598	Rcan2	regulator of calcineurin 2
chr12_+_110779204	10.952		Meg3	maternally expressed 3
chr4_-_109149038	10.772	NM_013876	Rnf11	ring finger protein 11
chr3_-_83967952	10.477		Trim2	tripartite motif-containing 2
chr17_-_13153182	10.460		Acat2	acetyl-Coenzyme A acetyltransferase 2
chr8_-_48373564	10.403		Stox2	storkhead box 2
chr19_-_10175990	10.400	NM_019699	Fads2	fatty acid desaturase 2
chr19_-_36194284	10.375	NM_013468	Ankrd1	ankyrin repeat domain 1 (cardiac muscle)
chr2_+_35159780	10.355		Gsn	gelsolin
chr4_-_75779379	10.305	NM_001014288	Ptprd	protein tyrosine phosphatase, receptor type, D
chr10_+_40603330	10.283	NM_031877	Wasf1	WASP family 1
chr19_-_7292057	10.156		Cox8a	cytochrome c oxidase, subunit VIIIa
chr5_-_124981292	10.151	NM_021430	Rilpl1	Rab interacting lysosomal protein-like 1
chr18_-_12978106	10.102		Osbpl1a	oxysterol binding protein-like 1A
chr9_-_75246118	10.019		Mapk6	mitogen-activated protein kinase 6
chr4_-_109149274	9.988		Rnf11	ring finger protein 11
chr5_-_124981025	9.939		Rilpl1	Rab interacting lysosomal protein-like 1
chr15_-_76881097	9.934	NM_013593	Mb	myoglobin
chr12_+_112783003	9.778		Eif5	eukaryotic translation initiation factor 5
chr15_+_58765328	9.772	NM_023172	Ndufb9	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr12_+_118896501	9.621		Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5
chr3_+_8509479	9.600	NM_025285	Stmn2	stathmin-like 2
chr2_+_33097791	9.591		Angptl2	angiopoietin-like 2
chr1_-_166371638	9.589		Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr18_+_37979242	9.559		Pcdhgc5	protocadherin gamma subfamily C, 5
chr1_-_36766756	9.545	NM_146107	Actr1b	ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr16_-_84955086	9.532		App	amyloid beta (A4) precursor protein
chr1_+_60761789	9.511		Eif4a1	eukaryotic translation initiation factor 4A1
chr12_+_30213224	9.506	NM_001093775 NM_001093778 NM_008666	Myt1l	myelin transcription factor 1-like
chr15_-_78034565	9.415	NM_013645	Pvalb	parvalbumin
chr13_-_30632975	9.372		Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr15_-_78034648	9.323		Pvalb	parvalbumin
chr3_+_101949321	9.313		Casq2	calsequestrin 2
chr13_-_36826104	9.310		Nrn1	neuritin 1
chr18_+_37925619	9.287		Pcdhga12	protocadherin gamma subfamily A, 12
chr4_+_151634973	9.287
chr7_+_53693190	9.273		Kcnc1	potassium voltage gated channel, Shaw-related subfamily, member 1
chr18_+_37880036	9.245	NM_033576	Pcdhgb4	protocadherin gamma subfamily B, 4
chr5_-_51945054	9.138	NM_008904	Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr11_+_29607599	9.085		Rtn4	reticulon 4
chr5_-_112821192	9.057	NM_028386	Asphd2	aspartate beta-hydroxylase domain containing 2
chr4_-_109959366	9.044	NM_001163399 NM_010488	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chrX_+_10062237	8.975	NM_019634	Tspan7	tetraspanin 7
chr3_+_94926272	8.967
chr7_+_69493148	8.947	NM_010882	Ndn	necdin
chr4_-_91066674	8.897	NM_207685	Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_+_20124648	8.887		Rab1	RAB1, member RAS oncogene family
chr18_+_37979199	8.818	NM_033583	Pcdhgb4 Pcdhgc5	protocadherin gamma subfamily B, 4 protocadherin gamma subfamily C, 5
chr13_-_100286521	8.811	NM_008634	Mtap1b	microtubule-associated protein 1B
chr12_-_87419813	8.804	NM_009368	Tgfb3	transforming growth factor, beta 3
chr19_-_5800268	8.746
chr10_-_13588578	8.715	NM_025446	Aig1	androgen-induced 1
chr13_-_100286446	8.711		Mtap1b	microtubule-associated protein 1B
chr11_-_115884885	8.620
chr13_-_36826245	8.611	NM_153529	Nrn1	neuritin 1
chr3_+_7366586	8.603	NM_008862	Pkia	protein kinase inhibitor, alpha
chr11_-_74491006	8.545		Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr7_-_133939596	8.544
chr2_+_157387284	8.489		Nnat	neuronatin
chr18_-_43847367	8.465	NM_001163637	Jakmip2	janus kinase and microtubule interacting protein 2
chr4_-_108311676	8.453
chr10_+_56107352	8.430		Gja1	gap junction protein, alpha 1
chr19_-_40476799	8.373	NM_001034964	Sorbs1	sorbin and SH3 domain containing 1
chr5_-_104543106	8.357	NM_010097	Sparcl1	SPARC-like 1
chr17_-_45708739	8.282		Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1
chrX_-_108651553	8.276	NM_025949	Rps6ka6	ribosomal protein S6 kinase polypeptide 6
chr5_-_104542729	8.269		Sparcl1	SPARC-like 1
chr8_-_49760037	8.263	NM_001145937 NM_011857	Odz3	odd Oz/ten-m homolog 3 (Drosophila)
chr19_-_5424694	8.240		Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)
chr15_+_12251184	8.239		Golph3	golgi phosphoprotein 3
chr1_-_137064124	8.232	NM_134438	Gpr37l1	G protein-coupled receptor 37-like 1
chr18_+_37821598	8.173	NM_033584	Pcdhga1	protocadherin gamma subfamily A, 1
chr5_-_104542598	8.169		Sparcl1	SPARC-like 1
chr7_-_25774918	8.163		Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr14_+_120724380	8.157		Mbnl2	muscleblind-like 2
chr5_-_104542751	8.151		Sparcl1	SPARC-like 1
chr5_-_104542641	8.133		Sparcl1	SPARC-like 1
chr11_-_55233581	8.122	NM_009242	Sparc	secreted acidic cysteine rich glycoprotein
chr8_+_55635683	8.088	NM_029569	Asb5	ankyrin repeat and SOCs box-containing 5
chr2_+_155215225	8.042		Trp53inp2	transformation related protein 53 inducible nuclear protein 2
chrX_-_132706705	8.020	NM_001168578 NM_025703	Tceal8	transcription elongation factor A (SII)-like 8
chr5_+_104864136	8.012	NM_009263	Spp1	secreted phosphoprotein 1
chr8_+_55635768	8.009		Asb5	ankyrin repeat and SOCs box-containing 5
chr5_-_134718500	7.980		Gtf2i	general transcription factor II I
chr1_+_137625754	7.884	NM_007791	Csrp1	cysteine and glycine-rich protein 1
chr5_+_104864146	7.807		Spp1	secreted phosphoprotein 1
chr12_-_42212538	7.789		Lrrn3	leucine rich repeat protein 3, neuronal
chr5_+_104864168	7.779		Spp1	secreted phosphoprotein 1
chr1_+_34364633	7.725		Dst	dystonin
chr6_-_124414668	7.722	NM_153508	Clstn3	calsyntenin 3
chr17_+_44090192	7.711		Rcan2	regulator of calcineurin 2
chr4_-_109960078	7.681	NM_001038698	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr6_+_37755974	7.665		Atp6v0c-ps2 Atp6v0c	ATPase, H+ transporting, lysosomal V0 subunit C, pseudogene 2 ATPase, H+ transporting, lysosomal V0 subunit C
chr7_-_74879894	7.647		Synm	synemin, intermediate filament protein
chr5_-_143665305	7.622		Actb	actin, beta
chr8_-_41597015	7.608		Cnot7	CCR4-NOT transcription complex, subunit 7
chr7_+_112788953	7.599		Fxc1	fractured callus expressed transcript 1
chr1_+_154802091	7.591		Nmnat2	nicotinamide nucleotide adenylyltransferase 2
chr2_+_136539202	7.578		Snap25	synaptosomal-associated protein 25
chr12_+_3960002	7.532		Pomc	pro-opiomelanocortin-alpha
chr4_+_129985957	7.519	NM_010174	Fabp3	fatty acid binding protein 3, muscle and heart
chr19_-_7292009	7.460		Cox8a	cytochrome c oxidase, subunit VIIIa
chr7_-_126127713	7.414		Gprc5b	G protein-coupled receptor, family C, group 5, member B
chr7_+_135689619	7.411		Bag3	BCL2-associated athanogene 3
chr8_-_87296172	7.396		Nfix	nuclear factor I/X
chr7_+_137789668	7.375		Tacc2	transforming, acidic coiled-coil containing protein 2
chr11_-_96680500	7.360		Nfe2l1	nuclear factor, erythroid derived 2,-like 1
chr19_-_5424473	7.344		Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)
chr7_+_112788972	7.338		Fxc1	fractured callus expressed transcript 1
chr16_+_45093784	7.328		Ccdc80	coiled-coil domain containing 80
chr16_-_85056592	7.318		App	amyloid beta (A4) precursor protein
chr8_+_87604829	7.292	NM_001001493	BC056474	cDNA sequence BC056474
chr3_-_80606500	7.277		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr2_+_59192308	7.271		Pkp4	plakophilin 4
chr11_+_100870759	7.227	NM_016920	Atp6v0a1	ATPase, H+ transporting, lysosomal V0 subunit A1
chr3_+_88433400	7.205		Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2
chr17_-_25922419	7.202		Haghl	hydroxyacylglutathione hydrolase-like
chr6_-_124779408	7.178	NM_013700	Usp5	ubiquitin specific peptidase 5 (isopeptidase T)
chr7_-_151622848	7.166		Cttn	cortactin
chr2_+_71367501	7.157	NM_010053	Dlx1	distal-less homeobox 1
chr1_+_154802144	7.130		Nmnat2	nicotinamide nucleotide adenylyltransferase 2
chr3_+_31048841	7.121	NM_008770	Cldn11	claudin 11
chr7_+_58877199	7.096	NM_080853	Slc17a6	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr7_+_31337558	7.069		Hspb6	heat shock protein, alpha-crystallin-related, B6
chr8_-_37631532	7.031		Dlc1	deleted in liver cancer 1
chr7_+_133968166	7.025	NM_001146347	Fam57b	family with sequence similarity 57, member B
chr6_+_48487567	7.001	NM_133764	Atp6v0e2	ATPase, H+ transporting, lysosomal V0 subunit E2
chr15_+_97942484	6.978	NM_021514	Pfkm	phosphofructokinase, muscle
chr7_-_110976499	6.958		Hbb-b1	hemoglobin, beta adult major chain
chr2_+_155207542	6.953		Trp53inp2	transformation related protein 53 inducible nuclear protein 2
chr17_-_48571942	6.922		Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr7_-_110962324	6.912		Hbb-b1 Hbb-b2	hemoglobin, beta adult major chain hemoglobin, beta adult minor chain
chr2_+_109514856	6.883	NM_007540	Bdnf	brain derived neurotrophic factor
chr8_+_87604638	6.874		BC056474	cDNA sequence BC056474
chrX_+_133371611	6.872		Plp1	proteolipid protein (myelin) 1
chr7_-_110962416	6.790	NM_008220 NM_016956	Hbb-b1 Hbb-b2	hemoglobin, beta adult major chain hemoglobin, beta adult minor chain
chr7_+_31076771	6.784	NM_001081114	Clip3	CAP-GLY domain containing linker protein 3
chr2_-_148233681	6.735		Thbd	thrombomodulin
chrX_-_53851108	6.730		Mmgt1	membrane magnesium transporter 1
chr1_+_45368443	6.686		Col3a1	collagen, type III, alpha 1
chrX_+_140100287	6.680	NM_001195049	Pak3	p21 protein (Cdc42/Rac)-activated kinase 3
chr17_-_25036364	6.659		Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3
chr12_+_8928949	6.656
chr14_+_120724163	6.649		Mbnl2	muscleblind-like 2
chr3_-_59066744	6.627	NM_027571	P2ry12	purinergic receptor P2Y, G-protein coupled 12

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.45	2.50e-17	GO:0051179	localization
1.49	1.06e-16	GO:0006810	transport
1.48	1.78e-16	GO:0051234	establishment of localization
1.46	1.37e-15	GO:0016043	cellular component organization
1.49	3.67e-15	GO:0048522	positive regulation of cellular process
1.58	1.84e-14	GO:0065008	regulation of biological quality
1.43	2.70e-14	GO:0071840	cellular component organization or biogenesis
1.44	8.19e-14	GO:0048518	positive regulation of biological process
1.48	4.94e-12	GO:0048523	negative regulation of cellular process
1.13	1.05e-11	GO:0009987	cellular process
1.45	1.16e-11	GO:0048519	negative regulation of biological process
1.46	7.71e-11	GO:0071842	cellular component organization at cellular level
1.20	3.18e-10	GO:0008152	metabolic process
1.59	1.12e-09	GO:0009056	catabolic process
1.42	1.47e-09	GO:0071841	cellular component organization or biogenesis at cellular level
1.21	3.17e-09	GO:0044237	cellular metabolic process
1.77	4.30e-09	GO:0051049	regulation of transport
1.64	5.91e-09	GO:0032879	regulation of localization
1.48	2.21e-07	GO:0065009	regulation of molecular function
1.38	3.48e-07	GO:0044267	cellular protein metabolic process
1.31	7.66e-07	GO:0007275	multicellular organismal development
1.47	9.97e-07	GO:0023051	regulation of signaling
1.64	1.17e-06	GO:0051128	regulation of cellular component organization
1.75	1.54e-06	GO:0046907	intracellular transport
1.56	1.69e-06	GO:0044248	cellular catabolic process
1.97	2.85e-06	GO:0006163	purine nucleotide metabolic process
1.54	3.33e-06	GO:0035556	intracellular signal transduction
1.34	3.36e-06	GO:0048731	system development
1.55	3.37e-06	GO:0051641	cellular localization
1.32	3.67e-06	GO:0019538	protein metabolic process
1.63	4.17e-06	GO:0045184	establishment of protein localization
1.28	4.25e-06	GO:0032502	developmental process
2.12	4.29e-06	GO:0009205	purine ribonucleoside triphosphate metabolic process
2.11	4.54e-06	GO:0009144	purine nucleoside triphosphate metabolic process
1.55	4.91e-06	GO:0008104	protein localization
1.63	5.41e-06	GO:0015031	protein transport
2.11	5.99e-06	GO:0009199	ribonucleoside triphosphate metabolic process
1.52	9.49e-06	GO:0010646	regulation of cell communication
2.20	9.69e-06	GO:0006091	generation of precursor metabolites and energy
2.04	1.11e-05	GO:0009150	purine ribonucleotide metabolic process
1.31	1.18e-05	GO:0048856	anatomical structure development
1.41	1.28e-05	GO:0044281	small molecule metabolic process
1.48	1.55e-05	GO:0033036	macromolecule localization
2.05	1.65e-05	GO:0009141	nucleoside triphosphate metabolic process
2.01	1.80e-05	GO:0009259	ribonucleotide metabolic process
1.17	2.43e-05	GO:0044238	primary metabolic process
1.57	3.05e-05	GO:0051649	establishment of localization in cell
1.67	3.72e-05	GO:0007155	cell adhesion
2.02	4.01e-05	GO:0051603	proteolysis involved in cellular protein catabolic process
1.67	4.53e-05	GO:0046483	heterocycle metabolic process
1.66	6.09e-05	GO:0022610	biological adhesion
1.46	7.34e-05	GO:0050790	regulation of catalytic activity
3.22	7.35e-05	GO:0009145	purine nucleoside triphosphate biosynthetic process
1.98	8.45e-05	GO:0044257	cellular protein catabolic process
1.82	9.04e-05	GO:0072521	purine-containing compound metabolic process
1.66	9.49e-05	GO:0016192	vesicle-mediated transport
1.51	9.90e-05	GO:0032268	regulation of cellular protein metabolic process
1.90	1.17e-04	GO:0006886	intracellular protein transport
2.55	1.33e-04	GO:0006164	purine nucleotide biosynthetic process
1.45	1.36e-04	GO:0009966	regulation of signal transduction
2.00	1.40e-04	GO:0006511	ubiquitin-dependent protein catabolic process
1.99	1.44e-04	GO:0019941	modification-dependent protein catabolic process
1.48	1.44e-04	GO:0051246	regulation of protein metabolic process
3.40	1.45e-04	GO:0006754	ATP biosynthetic process
3.13	1.48e-04	GO:0009142	nucleoside triphosphate biosynthetic process
1.70	1.65e-04	GO:0072358	cardiovascular system development
1.70	1.65e-04	GO:0072359	circulatory system development
1.73	1.82e-04	GO:0006753	nucleoside phosphate metabolic process
1.73	1.82e-04	GO:0009117	nucleotide metabolic process
1.97	1.93e-04	GO:0043632	modification-dependent macromolecule catabolic process
1.75	2.11e-04	GO:0034613	cellular protein localization
1.44	2.35e-04	GO:0007399	nervous system development
3.14	2.41e-04	GO:0009206	purine ribonucleoside triphosphate biosynthetic process
1.48	2.51e-04	GO:0010941	regulation of cell death
2.46	2.61e-04	GO:0072522	purine-containing compound biosynthetic process
1.79	2.72e-04	GO:0044057	regulation of system process
1.97	2.93e-04	GO:0007264	small GTPase mediated signal transduction
1.73	2.93e-04	GO:0070727	cellular macromolecule localization
3.10	3.38e-04	GO:0009201	ribonucleoside triphosphate biosynthetic process
1.89	3.45e-04	GO:0030163	protein catabolic process
2.34	5.52e-04	GO:0010498	proteasomal protein catabolic process
2.34	5.52e-04	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.21	5.63e-04	GO:0019222	regulation of metabolic process
1.23	5.91e-04	GO:0031323	regulation of cellular metabolic process
2.81	6.57e-04	GO:0009152	purine ribonucleotide biosynthetic process
1.79	7.06e-04	GO:0090066	regulation of anatomical structure size
1.66	7.12e-04	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.37	8.26e-04	GO:0051239	regulation of multicellular organismal process
1.63	9.26e-04	GO:0071844	cellular component assembly at cellular level
1.73	9.75e-04	GO:0051247	positive regulation of protein metabolic process
1.46	1.01e-03	GO:0042981	regulation of apoptosis
1.49	1.17e-03	GO:0022607	cellular component assembly
1.39	1.38e-03	GO:0031325	positive regulation of cellular metabolic process
1.83	1.41e-03	GO:0009894	regulation of catabolic process
1.37	1.52e-03	GO:0009893	positive regulation of metabolic process
1.37	1.54e-03	GO:0006996	organelle organization
1.63	1.69e-03	GO:0019725	cellular homeostasis
1.96	1.72e-03	GO:0051056	regulation of small GTPase mediated signal transduction
1.45	2.15e-03	GO:0043067	regulation of programmed cell death
3.85	2.18e-03	GO:0006096	glycolysis
1.66	2.20e-03	GO:0044282	small molecule catabolic process
1.50	2.30e-03	GO:0006811	ion transport
1.89	2.30e-03	GO:0031329	regulation of cellular catabolic process
1.34	2.36e-03	GO:0048583	regulation of response to stimulus
2.33	2.44e-03	GO:0043254	regulation of protein complex assembly
2.65	2.52e-03	GO:0009260	ribonucleotide biosynthetic process
3.33	3.06e-03	GO:0006007	glucose catabolic process
1.70	3.31e-03	GO:0043086	negative regulation of catalytic activity
1.51	3.34e-03	GO:0031399	regulation of protein modification process
1.80	3.35e-03	GO:0032535	regulation of cellular component size
1.49	3.59e-03	GO:0022008	neurogenesis
1.52	3.61e-03	GO:0055085	transmembrane transport
2.43	3.78e-03	GO:0048193	Golgi vesicle transport
2.00	4.23e-03	GO:0044087	regulation of cellular component biogenesis
1.70	4.25e-03	GO:0032270	positive regulation of cellular protein metabolic process
1.97	4.40e-03	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.37	4.46e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.46	4.56e-03	GO:0042592	homeostatic process
1.49	4.94e-03	GO:0055114	oxidation-reduction process
1.98	5.01e-03	GO:0046578	regulation of Ras protein signal transduction
1.96	5.08e-03	GO:0009203	ribonucleoside triphosphate catabolic process
1.52	5.12e-03	GO:0008219	cell death
1.32	5.22e-03	GO:0006464	protein modification process
2.67	5.25e-03	GO:0051351	positive regulation of ligase activity
3.49	5.29e-03	GO:0043242	negative regulation of protein complex disassembly
2.25	6.49e-03	GO:0046034	ATP metabolic process
1.94	6.76e-03	GO:0009146	purine nucleoside triphosphate catabolic process
1.93	6.80e-03	GO:0009261	ribonucleotide catabolic process
1.48	7.65e-03	GO:0044093	positive regulation of molecular function
1.55	8.59e-03	GO:0048878	chemical homeostasis
1.51	8.76e-03	GO:0016265	death
1.93	8.93e-03	GO:0009154	purine ribonucleotide catabolic process
1.93	8.93e-03	GO:0051129	negative regulation of cellular component organization
3.14	9.02e-03	GO:0019320	hexose catabolic process
1.53	9.06e-03	GO:0012501	programmed cell death
1.66	9.07e-03	GO:0061024	membrane organization
1.64	1.04e-02	GO:0044283	small molecule biosynthetic process
2.77	1.05e-02	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.63	1.11e-02	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.35	1.22e-02	GO:0009653	anatomical structure morphogenesis
2.42	1.29e-02	GO:0001666	response to hypoxia
1.90	1.35e-02	GO:0009143	nucleoside triphosphate catabolic process
2.73	1.38e-02	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.74	1.40e-02	GO:0031175	neuron projection development
1.65	1.41e-02	GO:0016044	cellular membrane organization
2.66	1.42e-02	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.40	1.44e-02	GO:0050793	regulation of developmental process
3.16	1.48e-02	GO:0031333	negative regulation of protein complex assembly
1.54	1.52e-02	GO:0006812	cation transport
2.12	1.55e-02	GO:0042692	muscle cell differentiation
1.57	1.60e-02	GO:0044092	negative regulation of molecular function
1.20	1.61e-02	GO:0080090	regulation of primary metabolic process
1.84	1.68e-02	GO:0061061	muscle structure development
2.77	1.73e-02	GO:0046164	alcohol catabolic process
2.77	1.73e-02	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.77	1.73e-02	GO:0051494	negative regulation of cytoskeleton organization
1.60	1.74e-02	GO:0051336	regulation of hydrolase activity
3.02	1.75e-02	GO:0046365	monosaccharide catabolic process
1.76	1.79e-02	GO:0046700	heterocycle catabolic process
3.37	1.88e-02	GO:0006084	acetyl-CoA metabolic process
1.52	1.90e-02	GO:0006915	apoptosis
2.37	1.98e-02	GO:0006006	glucose metabolic process
1.75	2.17e-02	GO:0034220	ion transmembrane transport
1.83	2.19e-02	GO:0072523	purine-containing compound catabolic process
2.45	2.19e-02	GO:0051340	regulation of ligase activity
1.84	2.22e-02	GO:0006195	purine nucleotide catabolic process
1.73	2.25e-02	GO:0001944	vasculature development
2.72	2.27e-02	GO:0044275	cellular carbohydrate catabolic process
2.35	2.43e-02	GO:0070482	response to oxygen levels
1.46	2.49e-02	GO:0048699	generation of neurons
1.59	2.78e-02	GO:0032989	cellular component morphogenesis
1.50	2.86e-02	GO:0007154	cell communication
3.03	2.88e-02	GO:0043244	regulation of protein complex disassembly
1.73	3.13e-02	GO:0044270	cellular nitrogen compound catabolic process
1.10	3.20e-02	GO:0065007	biological regulation
1.67	3.23e-02	GO:0044262	cellular carbohydrate metabolic process
1.61	3.57e-02	GO:0060341	regulation of cellular localization
5.05	3.93e-02	GO:0072384	organelle transport along microtubule
1.57	4.04e-02	GO:0060548	negative regulation of cell death
2.26	4.09e-02	GO:0031398	positive regulation of protein ubiquitination
2.04	4.12e-02	GO:0009165	nucleotide biosynthetic process
2.41	4.42e-02	GO:0051438	regulation of ubiquitin-protein ligase activity
2.28	4.44e-02	GO:0006936	muscle contraction
2.61	4.94e-02	GO:0051352	negative regulation of ligase activity
2.61	4.94e-02	GO:0051444	negative regulation of ubiquitin-protein ligase activity

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.47	1.36e-77	GO:0005737	cytoplasm
1.59	6.43e-66	GO:0044444	cytoplasmic part
1.32	1.83e-64	GO:0005622	intracellular
1.32	2.99e-62	GO:0044424	intracellular part
1.31	1.49e-43	GO:0043229	intracellular organelle
1.31	2.80e-43	GO:0043226	organelle
1.15	9.73e-36	GO:0005623	cell
1.15	9.73e-36	GO:0044464	cell part
1.30	9.02e-32	GO:0043227	membrane-bounded organelle
1.30	9.15e-32	GO:0043231	intracellular membrane-bounded organelle
1.94	7.15e-25	GO:0000267	cell fraction
1.82	1.38e-24	GO:0005739	mitochondrion
1.43	4.38e-24	GO:0044422	organelle part
1.42	4.62e-22	GO:0044446	intracellular organelle part
2.29	8.03e-21	GO:0043005	neuron projection
1.81	5.45e-19	GO:0031090	organelle membrane
1.92	3.73e-18	GO:0005626	insoluble fraction
1.48	1.50e-17	GO:0043234	protein complex
1.43	2.15e-17	GO:0032991	macromolecular complex
1.88	7.36e-16	GO:0005624	membrane fraction
1.76	3.60e-15	GO:0042995	cell projection
1.64	3.89e-15	GO:0005829	cytosol
2.57	1.20e-14	GO:0030425	dendrite
2.20	8.35e-13	GO:0031966	mitochondrial membrane
2.15	2.79e-12	GO:0005740	mitochondrial envelope
1.99	7.66e-12	GO:0044429	mitochondrial part
1.57	1.56e-11	GO:0005856	cytoskeleton
2.24	3.37e-11	GO:0044297	cell body
3.19	4.09e-11	GO:0043292	contractile fiber
1.70	5.77e-11	GO:0005794	Golgi apparatus
1.41	7.87e-11	GO:0043228	non-membrane-bounded organelle
1.41	7.87e-11	GO:0043232	intracellular non-membrane-bounded organelle
1.87	1.21e-10	GO:0031975	envelope
1.87	1.83e-10	GO:0031967	organelle envelope
2.22	2.82e-10	GO:0043025	neuronal cell body
1.98	3.24e-10	GO:0045202	synapse
3.18	5.65e-10	GO:0030016	myofibril
2.33	1.43e-09	GO:0030424	axon
3.39	2.23e-09	GO:0030017	sarcomere
3.21	2.39e-09	GO:0044449	contractile fiber part
1.29	2.52e-09	GO:0071944	cell periphery
2.17	3.60e-09	GO:0005743	mitochondrial inner membrane
2.09	6.17e-09	GO:0005625	soluble fraction
1.97	1.74e-08	GO:0044463	cell projection part
2.09	2.47e-08	GO:0019866	organelle inner membrane
2.12	7.53e-08	GO:0048471	perinuclear region of cytoplasm
1.27	1.16e-07	GO:0005886	plasma membrane
1.74	1.27e-07	GO:0030054	cell junction
3.71	3.14e-07	GO:0000502	proteasome complex
1.58	4.38e-07	GO:0044430	cytoskeletal part
2.00	5.02e-07	GO:0044456	synapse part
1.39	9.42e-07	GO:0044459	plasma membrane part
2.60	1.46e-06	GO:0019717	synaptosome
1.52	2.23e-06	GO:0005783	endoplasmic reticulum
1.61	2.45e-06	GO:0031982	vesicle
2.04	3.10e-06	GO:0015629	actin cytoskeleton
1.59	4.59e-06	GO:0012505	endomembrane system
1.72	5.36e-06	GO:0031988	membrane-bounded vesicle
1.62	5.55e-06	GO:0031410	cytoplasmic vesicle
2.55	6.30e-06	GO:0033267	axon part
1.14	9.25e-06	GO:0016020	membrane
2.34	1.54e-05	GO:0044433	cytoplasmic vesicle part
1.71	1.60e-05	GO:0016023	cytoplasmic membrane-bounded vesicle
2.36	1.64e-05	GO:0030659	cytoplasmic vesicle membrane
3.24	1.92e-05	GO:0031674	I band
2.39	2.27e-05	GO:0005938	cell cortex
2.24	4.61e-05	GO:0012506	vesicle membrane
3.28	1.89e-04	GO:0030018	Z disc
2.18	2.63e-04	GO:0030135	coated vesicle
1.87	2.77e-04	GO:0044431	Golgi apparatus part
1.60	3.38e-04	GO:0015630	microtubule cytoskeleton
2.89	4.33e-04	GO:0030662	coated vesicle membrane
2.45	1.03e-03	GO:0044455	mitochondrial membrane part
1.42	1.57e-03	GO:0044421	extracellular region part
3.61	2.13e-03	GO:0030666	endocytic vesicle membrane
2.13	2.79e-03	GO:0030136	clathrin-coated vesicle
2.96	3.87e-03	GO:0030665	clathrin coated vesicle membrane
3.41	4.88e-03	GO:0016469	proton-transporting two-sector ATPase complex
1.46	5.61e-03	GO:0005615	extracellular space
2.48	5.96e-03	GO:0005802	trans-Golgi network
1.69	6.84e-03	GO:0031012	extracellular matrix
2.61	7.95e-03	GO:0030139	endocytic vesicle
4.43	9.79e-03	GO:0005839	proteasome core complex
2.72	9.93e-03	GO:0030117	membrane coat
2.72	9.93e-03	GO:0048475	coated membrane
2.76	1.25e-02	GO:0005901	caveola
2.41	1.51e-02	GO:0030427	site of polarized growth
2.99	1.74e-02	GO:0005905	coated pit
1.88	1.90e-02	GO:0045121	membrane raft
1.72	2.25e-02	GO:0005874	microtubule
2.26	2.41e-02	GO:0005741	mitochondrial outer membrane
6.32	3.38e-02	GO:0019773	proteasome core complex, alpha-subunit complex
2.21	3.51e-02	GO:0008021	synaptic vesicle
2.33	3.72e-02	GO:0014069	postsynaptic density
2.33	3.72e-02	GO:0042383	sarcolemma

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.43	7.48e-37	GO:0005515	protein binding
1.20	6.88e-25	GO:0005488	binding
1.96	2.46e-10	GO:0008092	cytoskeletal protein binding
1.24	7.51e-10	GO:0003824	catalytic activity
2.14	9.99e-10	GO:0032403	protein complex binding
2.05	1.12e-06	GO:0003779	actin binding
1.40	1.45e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.38	3.03e-06	GO:0032555	purine ribonucleotide binding
1.38	3.22e-06	GO:0032553	ribonucleotide binding
1.58	3.86e-06	GO:0019899	enzyme binding
1.38	4.58e-06	GO:0017076	purine nucleotide binding
1.34	7.86e-06	GO:0000166	nucleotide binding
1.53	2.27e-05	GO:0022892	substrate-specific transporter activity
1.46	6.91e-05	GO:0005215	transporter activity
1.53	1.82e-04	GO:0022891	substrate-specific transmembrane transporter activity
1.49	4.28e-04	GO:0022857	transmembrane transporter activity
1.36	6.94e-04	GO:0005524	ATP binding
1.54	7.34e-04	GO:0015075	ion transmembrane transporter activity
1.34	1.78e-03	GO:0032559	adenyl ribonucleotide binding
1.59	1.98e-03	GO:0019904	protein domain specific binding
1.33	2.56e-03	GO:0030554	adenyl nucleotide binding
6.12	4.16e-03	GO:0046933	hydrogen ion transporting ATP synthase activity, rotational mechanism
1.40	4.62e-03	GO:0005102	receptor binding
1.58	5.96e-03	GO:0008324	cation transmembrane transporter activity
1.49	7.87e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.49	8.46e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
1.50	8.74e-03	GO:0017111	nucleoside-triphosphatase activity
1.48	1.05e-02	GO:0016462	pyrophosphatase activity
2.19	1.11e-02	GO:0005516	calmodulin binding
2.06	1.42e-02	GO:0015077	monovalent inorganic cation transmembrane transporter activity
1.45	1.62e-02	GO:0046983	protein dimerization activity
1.66	1.65e-02	GO:0019001	guanyl nucleotide binding
1.66	1.65e-02	GO:0032561	guanyl ribonucleotide binding
2.72	1.67e-02	GO:0042625	ATPase activity, coupled to transmembrane movement of ions
1.89	1.85e-02	GO:0022890	inorganic cation transmembrane transporter activity
1.41	2.30e-02	GO:0016301	kinase activity
1.66	2.32e-02	GO:0005525	GTP binding
1.23	2.77e-02	GO:0016787	hydrolase activity
1.51	3.55e-02	GO:0005509	calcium ion binding
1.44	4.14e-02	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.70	4.30e-02	GO:0022836	gated channel activity