Motif ID: NFE2L2.p2

Z-value: 1.290


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
Nfe2l2 18024 nuclear factor, erythroid derived 2, like 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfe2l2chr2_-_755425350.257.1e-04Click!


Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_98862163 17.476 Top2a
topoisomerase (DNA) II alpha
chr7_-_133942605 14.448 NM_001177307
Aldoa
aldolase A, fructose-bisphosphate
chr2_+_151931424 13.990 Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr7_-_133942767 13.675 NM_007438
Aldoa
aldolase A, fructose-bisphosphate
chr9_+_7272513 12.107 NM_008607
Mmp13
matrix metallopeptidase 13
chr5_-_140212063 11.965 NM_174850
Micall2
MICAL-like 2
chr2_-_25079684 11.384 Tubb2c
tubulin, beta 2C
chr15_-_100517580 11.303 Cela1
chymotrypsin-like elastase family, member 1
chr11_-_43561446 11.030 NM_133795
Ttc1
tetratricopeptide repeat domain 1
chr8_-_110112368 10.962 NM_010817
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr5_+_67067497 10.957 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr5_-_136410488 10.685 NM_018871
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chrX_+_71669985 10.628 Ikbkg
inhibitor of kappaB kinase gamma
chr8_+_34763918 10.310 Gsr
glutathione reductase
chr14_+_63754443 10.272 Ctsb
cathepsin B
chr3_+_121948541 10.125 Gclm
glutamate-cysteine ligase, modifier subunit
chr6_-_16848352 10.082 NM_031198
Tcfec
transcription factor EC
chr2_+_151931465 10.001 NM_029688
Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr3_+_121948693 9.805 Gclm
glutamate-cysteine ligase, modifier subunit
chr11_-_50024275 9.545 NM_011018
Sqstm1
sequestosome 1
chr5_+_30339682 9.517 NM_031168
Il6
interleukin 6
chr3_-_88297220 9.356 NM_019390
Lmna
lamin A
chr9_-_21043503 9.082 Keap1
kelch-like ECH-associated protein 1
chr3_+_121948399 8.661 NM_008129
Gclm
glutamate-cysteine ligase, modifier subunit
chr7_-_29965655 8.555 NM_026545
Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr3_+_89225539 8.551 NM_001113331
Shc1
src homology 2 domain-containing transforming protein C1
chr17_-_45729199 8.458 NM_022880
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr1_+_87961184 8.329 NM_027357
Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chrX_+_71669971 8.277 Ikbkg
inhibitor of kappaB kinase gamma
chr6_-_16848314 8.271 Tcfec
transcription factor EC
chr9_-_75257067 8.113 NM_027418
Mapk6
mitogen-activated protein kinase 6
chr11_+_107340794 8.048 NM_025894
Psmd12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr2_+_156301543 7.969 NM_001006664
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr2_+_164773719 7.940 NM_013599
Mmp9
matrix metallopeptidase 9
chrX_-_131117602 7.929 NM_013482
Btk
Bruton agammaglobulinemia tyrosine kinase
chr17_+_35187185 7.884 NM_033444
Clic1
chloride intracellular channel 1
chr6_+_38868942 7.810 NM_011539
Tbxas1
thromboxane A synthase 1, platelet
chr16_-_16073490 7.636 2310008H04Rik
RIKEN cDNA 2310008H04 gene
chr18_-_35114005 7.530 Hspa9
heat shock protein 9
chrX_+_160707362 7.526 NM_027153
Pir
pirin
chr16_-_22121346 7.367 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr11_-_50125157 7.197 Canx
calnexin
chr18_-_35114000 7.153 Hspa9
heat shock protein 9
chr8_+_73435716 7.035 Mtap1s
microtubule-associated protein 1S
chr17_+_35187325 7.011 Clic1
chloride intracellular channel 1
chr5_-_92777875 6.710 NM_021274
Cxcl10
chemokine (C-X-C motif) ligand 10
chr18_-_35114004 6.628 NM_010481
Hspa9
heat shock protein 9
chr9_-_21043246 6.594 Keap1
kelch-like ECH-associated protein 1
chr7_+_135667095 6.516 NM_013863
Bag3
BCL2-associated athanogene 3
chr18_-_35113995 6.507 Hspa9
heat shock protein 9
chr1_+_176102903 6.406 NM_011465
Spna1
spectrin alpha 1
chr8_-_72498125 6.286 Gatad2a
GATA zinc finger domain containing 2A
chr18_-_35113903 6.278 Hspa9
heat shock protein 9
chr7_-_13623158 6.244 NM_145578
Ube2m
ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
chr11_+_120534337 6.130 Aspscr1
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr19_-_7557553 6.116 Rtn3
reticulon 3
chr17_-_45710161 6.084 NM_008302
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr5_-_21290925 6.010 Dnajc2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr2_-_125549883 5.933 NM_199022
Shc4
SHC (Src homology 2 domain containing) family, member 4
chr1_-_179178874 5.931 NM_011785
Akt3
thymoma viral proto-oncogene 3
chr2_+_3630817 5.915 Fam107b
family with sequence similarity 107, member B
chr10_-_117147068 5.866 Mdm2
transformed mouse 3T3 cell double minute 2
chr18_-_10029925 5.823 NM_001038589
NM_021522
Usp14

ubiquitin specific peptidase 14

chr8_-_73030573 5.750 NM_025577
2810428I15Rik
RIKEN cDNA 2810428I15 gene
chr11_+_23156482 5.704 Xpo1
exportin 1, CRM1 homolog (yeast)
chr16_+_20651724 5.612 NM_134101
Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr2_+_155576833 5.583 Procr
protein C receptor, endothelial
chr11_+_120494714 5.551


chr9_-_21043375 5.520 Keap1
kelch-like ECH-associated protein 1
chr2_+_156301651 5.419 Epb4.1l1
erythrocyte protein band 4.1-like 1
chr17_-_45710213 5.418 Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr2_-_4912152 5.382 Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr7_-_108112785 5.352 NM_183168
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chrX_+_71669933 5.314 NM_001136067
NM_001161421
Ikbkg

inhibitor of kappaB kinase gamma

chrX_+_102275071 5.298 NM_026312
2610029G23Rik
RIKEN cDNA 2610029G23 gene
chr9_-_21043659 5.278 NM_001110305
NM_001110306
NM_001110307
NM_016679
Keap1



kelch-like ECH-associated protein 1



chr2_+_24192373 5.257 NM_031167
Il1rn
interleukin 1 receptor antagonist
chr2_+_90894747 5.244 Psmc3
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr2_+_167514489 5.207 Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr5_+_91332895 5.019 NM_009140
Cxcl2
chemokine (C-X-C motif) ligand 2
chr5_-_121227617 4.983 NM_145226
Oas3
2'-5' oligoadenylate synthetase 3
chr10_+_59740373 4.951 NM_001146120
NM_001146121
NM_001146122
NM_001146123
NM_011179
Psap




prosaposin




chr17_+_56092075 4.925 Ebi3
Epstein-Barr virus induced gene 3
chr2_-_38499436 4.888 Psmb7
proteasome (prosome, macropain) subunit, beta type 7
chr17_+_29089357 4.852 Kctd20
potassium channel tetramerisation domain containing 20
chr19_-_8787823 4.765 Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr17_+_29089623 4.694 Kctd20
potassium channel tetramerisation domain containing 20
chr8_-_4779533 4.666 NM_011369
Shcbp1
Shc SH2-domain binding protein 1
chr11_+_120328948 4.662 NM_001159328
NM_008244
Hgs

HGF-regulated tyrosine kinase substrate

chr14_+_68334187 4.657 Kctd9
potassium channel tetramerisation domain containing 9
chr8_-_113862056 4.625 Mlkl
mixed lineage kinase domain-like
chr1_-_90406613 4.624 NM_008132
Glrp1
glutamine repeat protein 1
chr6_+_129483154 4.583 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr2_-_25080099 4.581 Tubb2c
tubulin, beta 2C
chr8_-_73030643 4.564 2810428I15Rik
RIKEN cDNA 2810428I15 gene
chr15_-_56526052 4.514 NM_008216
Has2
hyaluronan synthase 2
chr5_-_21290971 4.498 NM_009584
Dnajc2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr18_+_83080270 4.452 NM_183033
Zfp516
zinc finger protein 516
chr2_-_25210076 4.438 Dpp7
dipeptidylpeptidase 7
chr7_+_135667279 4.405 Bag3
BCL2-associated athanogene 3
chr2_-_38499375 4.365 NM_011187
Psmb7
proteasome (prosome, macropain) subunit, beta type 7
chr15_-_57702643 4.364 Derl1
Der1-like domain family, member 1
chr4_-_58925575 4.352 NM_172381
AI314180
expressed sequence AI314180
chr12_+_112776828 4.336 Eif5
eukaryotic translation initiation factor 5
chr3_+_146515330 4.269 NM_027594
Ttll7
tubulin tyrosine ligase-like family, member 7
chr18_-_64676144 4.255 Nars
asparaginyl-tRNA synthetase
chrX_+_90920450 4.247 NM_211138
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr6_+_129483238 4.142 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr2_+_32483909 4.111 NM_001198792
Ak1
adenylate kinase 1
chr2_-_25127860 3.987 NM_023464
Ssna1
Sjogren's syndrome nuclear autoantigen 1
chr10_+_87553816 3.964 NM_029971
Pmch
pro-melanin-concentrating hormone
chr9_-_108962219 3.962 NM_011637
Trex1
three prime repair exonuclease 1
chr2_+_90894161 3.905 NM_008948
Psmc3
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr10_+_59740430 3.805 Psap
prosaposin
chr8_-_110112260 3.775 Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr11_+_72263260 3.742


chr13_+_96466807 3.695 NM_010170
F2rl2
coagulation factor II (thrombin) receptor-like 2
chr5_+_43624701 3.681 NM_001177379
NM_175937
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chr19_+_3283038 3.608 NM_172252
Mrpl21
mitochondrial ribosomal protein L21
chr19_+_46380418 3.603 NM_001177370
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
chr18_-_63851841 3.568 NM_016792
Txnl1
thioredoxin-like 1
chr9_-_108961721 3.530 NM_001012236
Trex1
three prime repair exonuclease 1
chr6_+_34304098 3.504 NM_008012
Akr1b8
aldo-keto reductase family 1, member B8
chr11_-_109334909 3.491 NM_001029842
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr2_+_11627385 3.490 NM_008358
Il15ra
interleukin 15 receptor, alpha chain
chr6_+_48986501 3.485 NM_053110
Gpnmb
glycoprotein (transmembrane) nmb
chr10_+_110910277 3.452 Nap1l1
nucleosome assembly protein 1-like 1
chr6_-_83267540 3.434 NM_008638
Mthfd2
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr7_+_52104591 3.421 NM_026270
Akt1s1
AKT1 substrate 1 (proline-rich)
chr11_-_87800086 3.416 NM_001168472
Dynll2
dynein light chain LC8-type 2
chr13_-_58316923 3.367 Ubqln1
ubiquilin 1
chr19_-_7557690 3.362 NM_053076
NM_001003933
NM_001003934
Rtn3


reticulon 3


chr18_-_64676090 3.362 Nars
asparaginyl-tRNA synthetase
chr16_+_32430986 3.362 NM_009981
NM_001163159
Pcyt1a

phosphate cytidylyltransferase 1, choline, alpha isoform

chr3_+_146515369 3.360 Ttll7
tubulin tyrosine ligase-like family, member 7
chrX_-_99352341 3.301 NM_146235
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 - like
chr6_+_145756902 3.287 NM_027760
Rassf8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr18_-_64676160 3.263 NM_001142950
NM_027350
Nars

asparaginyl-tRNA synthetase

chr11_-_100565382 3.246 NM_030150
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr17_+_28829512 3.226 NM_001168513
Mapk14
mitogen-activated protein kinase 14
chr11_-_120979990 3.187 NM_027622
Tex19.2
testis expressed gene 19.2
chr1_-_79436564 3.172 NM_009129
Scg2
secretogranin II
chr12_-_113205172 3.127 NM_027360
2010107E04Rik
RIKEN cDNA 2010107E04 gene
chr3_+_108060061 3.112 Psma5
proteasome (prosome, macropain) subunit, alpha type 5
chr12_-_113205152 3.104 2010107E04Rik
RIKEN cDNA 2010107E04 gene
chr7_+_5996762 3.102 NM_031389
Nlrp4c
NLR family, pyrin domain containing 4C
chr7_-_35015309 3.031 NM_008155
Gpi1
glucose phosphate isomerase 1
chr11_-_120298946 3.005 NM_001195023
NM_199469
Nploc4

nuclear protein localization 4 homolog (S. cerevisiae)

chr13_+_75977323 2.981 NM_053108
Glrx
glutaredoxin
chr2_+_155576943 2.975 NM_011171
Procr
protein C receptor, endothelial
chr11_+_121007456 2.961 NM_028602
Tex19.1
testis expressed gene 19.1
chr4_-_57969277 2.960 NM_011660
Txn1
thioredoxin 1
chr7_+_148654681 2.959 NM_001111050
Cd151
CD151 antigen
chr7_-_30980042 2.950 NM_009795
Capns1
calpain, small subunit 1
chr8_-_129469539 2.945 Tomm20
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr2_+_90894434 2.926 Psmc3
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr14_+_68334154 2.925 NM_001111028
NM_134073
Kctd9

potassium channel tetramerisation domain containing 9

chrX_+_156278399 2.899 NM_001135728
Sh3kbp1
SH3-domain kinase binding protein 1
chrX_+_12858142 2.890 NM_010028
Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr5_-_109104366 2.882 Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr8_+_125372273 2.860 NM_007662
Cdh15
cadherin 15
chr5_-_109104394 2.860 Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr8_+_96696512 2.821 NM_008630
Mt2
metallothionein 2
chr6_+_48986625 2.808 Gpnmb
glycoprotein (transmembrane) nmb
chr14_-_21212834 2.805 Mrps16
mitochondrial ribosomal protein S16
chr7_+_31338319 2.798 NM_001012401
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr13_-_64471609 2.778 NM_009984
Ctsl
cathepsin L
chr7_-_148202779 2.767 NM_001033632
Ifitm6
interferon induced transmembrane protein 6
chr1_+_109486582 2.743 NM_001159748
NM_011459
Serpinb8

serine (or cysteine) peptidase inhibitor, clade B, member 8

chr8_+_112302530 2.732 NM_009677
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr11_-_69575192 2.719 NM_019871
Amac1
acyl-malonyl condensing enzyme 1
chr12_-_77896534 2.719 NM_030677
Gpx2
glutathione peroxidase 2
chr7_-_35015297 2.693 Gpi1
glucose phosphate isomerase 1
chr7_+_117916117 2.677 NM_009667
Ampd3
adenosine monophosphate deaminase 3
chr10_+_79727708 2.666 NM_001122604
NM_001122605
NM_133188
Dazap1


DAZ associated protein 1


chr5_-_100929644 2.660 NM_172714
Lin54
lin-54 homolog (C. elegans)
chr3_+_94926272 2.617


chr11_-_114795651 2.603 NM_199221
Cd300lb
CD300 antigen like family member B
chrX_-_140261831 2.575 Capn6
calpain 6
chr11_-_74991244 2.574 Ovca2
candidate tumor suppressor in ovarian cancer 2
chr5_-_109104347 2.530 Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr2_+_121854287 2.525 NM_144545
Eif3j
eukaryotic translation initiation factor 3, subunit J
chr8_+_34763709 2.510 NM_010344
Gsr
glutathione reductase
chr2_-_163245205 2.504 NM_025699
3230401D17Rik
RIKEN cDNA 3230401D17 gene
chr12_-_77896363 2.495 Gpx2
glutathione peroxidase 2
chr3_-_89151364 2.482 Adam15
a disintegrin and metallopeptidase domain 15 (metargidin)
chr18_+_12802276 2.465 Ttc39c
tetratricopeptide repeat domain 39C
chr12_+_112997194 2.444 Klc1
kinesin light chain 1
chr3_+_28704426 2.440 NM_026517
Rpl22l1
ribosomal protein L22 like 1
chr3_+_28704357 2.420 Rpl22l1
ribosomal protein L22 like 1
chrX_-_140261954 2.405 NM_007603
Capn6
calpain 6
chr16_-_22439642 2.402 NM_023794
Etv5
ets variant gene 5
chr1_+_137914574 2.397 NM_025439
Tmem9
transmembrane protein 9
chr2_-_162915336 2.395 NM_026630
Gtsf1l
gametocyte specific factor 1-like
chr11_-_115884885 2.387


chr13_-_19711409 2.383 NM_134065
Epdr1
ependymin related protein 1 (zebrafish)
chr1_-_31006599 2.373 NM_011200
Ptp4a1
protein tyrosine phosphatase 4a1
chr7_+_86058650 2.362 NM_020583
Isg20
interferon-stimulated protein
chr7_+_134388553 2.356 Zfp771
zinc finger protein 771
chr3_-_107877497 2.353 Ampd2
adenosine monophosphate deaminase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
7.19 1.98e-07 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
7.09 2.52e-07 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.50 3.41e-07 GO:0051351 positive regulation of ligase activity
6.63 7.96e-07 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
7.07 9.16e-07 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.29 1.86e-06 GO:0051443 positive regulation of ubiquitin-protein ligase activity
6.67 2.30e-06 GO:0051352 negative regulation of ligase activity
6.67 2.30e-06 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.32 2.47e-06 GO:0008152 metabolic process
5.73 3.00e-06 GO:0051340 regulation of ligase activity
5.02 1.07e-05 GO:0031398 positive regulation of protein ubiquitination
5.53 1.49e-05 GO:0051438 regulation of ubiquitin-protein ligase activity
1.33 1.95e-05 GO:0044238 primary metabolic process
1.58 4.80e-05 GO:0019538 protein metabolic process
5.39 6.11e-05 GO:0031397 negative regulation of protein ubiquitination
4.00 2.26e-04 GO:0031396 regulation of protein ubiquitination
2.17 3.33e-04 GO:0006508 proteolysis
1.30 3.39e-04 GO:0044237 cellular metabolic process
3.75 3.46e-04 GO:0031400 negative regulation of protein modification process
1.99 4.18e-04 GO:0032268 regulation of cellular protein metabolic process
2.61 4.20e-04 GO:0032270 positive regulation of cellular protein metabolic process
2.79 4.84e-04 GO:0031401 positive regulation of protein modification process
3.91 6.76e-04 GO:0010498 proteasomal protein catabolic process
3.91 6.76e-04 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
2.12 6.93e-04 GO:0031399 regulation of protein modification process
2.63 8.05e-04 GO:0000278 mitotic cell cycle
1.90 9.98e-04 GO:0051246 regulation of protein metabolic process
2.50 1.20e-03 GO:0051247 positive regulation of protein metabolic process
2.99 2.00e-03 GO:0032269 negative regulation of cellular protein metabolic process
1.56 2.27e-03 GO:0044267 cellular protein metabolic process
2.86 4.41e-03 GO:0051248 negative regulation of protein metabolic process
2.80 6.65e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.31 8.64e-03 GO:0043170 macromolecule metabolic process
2.73 9.89e-03 GO:0019941 modification-dependent protein catabolic process
2.71 1.13e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.66 1.20e-02 GO:0065009 regulation of molecular function
1.75 1.22e-02 GO:0050790 regulation of catalytic activity
1.44 1.71e-02 GO:0016043 cellular component organization
8.64 1.73e-02 GO:0010970 microtubule-based transport
8.64 1.73e-02 GO:0030705 cytoskeleton-dependent intracellular transport
2.65 1.75e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
2.60 2.37e-02 GO:0044257 cellular protein catabolic process
2.29 2.97e-02 GO:0043086 negative regulation of catalytic activity
12.34 4.79e-02 GO:0008088 axon cargo transport

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
10.04 6.58e-13 GO:0000502 proteasome complex
1.28 1.06e-12 GO:0005622 intracellular
1.29 2.04e-12 GO:0044424 intracellular part
1.37 1.12e-11 GO:0005737 cytoplasm
1.28 3.03e-08 GO:0043226 organelle
1.27 5.38e-08 GO:0043229 intracellular organelle
1.41 1.18e-07 GO:0044444 cytoplasmic part
1.12 2.11e-05 GO:0005623 cell
1.12 2.11e-05 GO:0044464 cell part
1.23 1.75e-04 GO:0043227 membrane-bounded organelle
1.22 4.51e-04 GO:0043231 intracellular membrane-bounded organelle
1.70 4.89e-04 GO:0005829 cytosol
1.62 6.46e-03 GO:0005856 cytoskeleton
1.35 2.26e-02 GO:0032991 macromolecular complex
1.38 3.07e-02 GO:0043234 protein complex
1.70 4.92e-02 GO:0044430 cytoskeletal part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.38 1.18e-05 GO:0003824 catalytic activity
1.19 6.33e-05 GO:0005488 binding
1.57 3.27e-04 GO:0016787 hydrolase activity
2.05 6.93e-03 GO:0008233 peptidase activity
1.26 9.60e-03 GO:0005515 protein binding
29.61 1.65e-02 GO:0015037 peptide disulfide oxidoreductase activity
1.98 2.81e-02 GO:0070011 peptidase activity, acting on L-amino acid peptides
2.27 3.09e-02 GO:0004175 endopeptidase activity