Motif ID: NFIL3.p2

Z-value: 1.122


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
Nfil3 18030 nuclear factor, interleukin 3, regulated

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfil3chr13_-_53076251-0.018.5e-01Click!


Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_90889913 41.209 NM_009654
Alb
albumin
chr5_+_90889937 33.942 Alb
albumin
chr19_-_38199036 33.154 Rbp4
retinol binding protein 4, plasma
chr19_-_38199737 31.428 NM_001159487
Rbp4
retinol binding protein 4, plasma
chr19_-_38199267 27.121 Rbp4
retinol binding protein 4, plasma
chr19_-_38199291 26.746 NM_011255
Rbp4
retinol binding protein 4, plasma
chr19_-_38199112 23.960 Rbp4
retinol binding protein 4, plasma
chr8_-_95721654 21.443 Ces1d
carboxylesterase 1D
chr8_-_95721702 20.478 NM_053200
Ces1d
carboxylesterase 1D
chr10_+_4978808 18.464 Syne1
synaptic nuclear envelope 1
chr12_+_118896501 14.668 Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr2_-_25325248 14.120 NM_008963
Ptgds
prostaglandin D2 synthase (brain)
chr17_+_25945986 13.737 NM_001164225
Fbxl16
F-box and leucine-rich repeat protein 16
chr15_+_78744862 12.174 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr1_-_42749940 11.196 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr4_+_101180625 10.227 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr15_-_8660729 9.460 NM_148938
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_41918624 9.456 NM_133653
Mat1a
methionine adenosyltransferase I, alpha
chr19_-_41151561 9.353 NM_153520
Opalin
oligodendrocytic myelin paranodal and inner loop protein
chr4_-_60594959 9.154 NM_001122647
Mup10
LOC100048884
Mup1
major urinary protein 10
novel member of the major urinary protein (Mup) gene family
major urinary protein 1
chr13_-_25361773 9.099 NM_009513
Nrsn1
neurensin 1
chr2_+_102546576 8.786 NM_001077515
NM_011393
Slc1a2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr6_-_55631256 8.583 NM_009717
Neurod6
neurogenic differentiation 6
chr2_+_143371807 8.267 NM_008792
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr15_-_8660462 7.678 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_+_91991704 7.654 NM_001159647
Cntn1
contactin 1
chr6_-_55631085 7.312 Neurod6
neurogenic differentiation 6
chr4_-_109959366 7.107 NM_001163399
NM_010488
Elavl4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr15_+_68758773 7.043 NM_010158
Khdrbs3
KH domain containing, RNA binding, signal transduction associated 3
chr4_-_120689813 7.000 NM_133716
Smap2
stromal membrane-associated GTPase-activating protein 2
chr6_+_54251485 6.985


chr15_-_8660479 6.725 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_102291924 6.716 NM_010218
Fjx1
four jointed box 1 (Drosophila)
chr6_-_55631039 6.685 Neurod6
neurogenic differentiation 6
chr4_-_104548965 6.487 NM_146148
C8a
complement component 8, alpha polypeptide
chr10_+_40657980 6.455 Wasf1
WASP family 1
chr4_+_101180580 6.429 NM_001164584
NM_001164585
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_84851029 6.369 Sh3gl2
SH3-domain GRB2-like 2
chr4_-_109959185 6.340 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_-_82068951 6.323 Slc10a1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr16_+_22951183 5.927 Hrg
histidine-rich glycoprotein
chr15_-_8660442 5.906 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_93355893 5.873 NM_011066
Per2
period homolog 2 (Drosophila)
chr16_+_22951144 5.731 NM_053176
Hrg
histidine-rich glycoprotein
chr15_+_81633192 5.551 Tef
thyrotroph embryonic factor
chr19_+_23215704 5.535 NM_010638
Klf9
Kruppel-like factor 9
chr8_-_95655156 5.348 NM_007954
Ces1c
carboxylesterase 1C
chr10_-_24647173 5.284 Arg1
arginase, liver
chr13_+_42961598 5.199 Phactr1
phosphatase and actin regulator 1
chr12_-_82069060 5.134 NM_001177561
NM_011387
Slc10a1

solute carrier family 10 (sodium/bile acid cotransporter family), member 1

chr3_-_113277601 5.052 NM_007446
Amy1
amylase 1, salivary
chr10_+_23571267 5.021 NM_011979
Vnn3
vanin 3
chr1_-_58642994 5.007 NM_172513
Fam126b
family with sequence similarity 126, member B
chr11_-_79343891 4.823 Evi2a
ecotropic viral integration site 2a
chr1_-_142079842 4.803 NM_009888
Cfh
complement component factor h
chr10_+_126857922 4.703 NM_001168293
NM_027900
R3hdm2

R3H domain containing 2

chr11_-_101949793 4.680 NM_016695
Mpp2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr5_-_87355527 4.666 NM_152811
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
chr19_+_23215725 4.664 Klf9
Kruppel-like factor 9
chr3_+_59835700 4.493 NM_023383
Aadac
arylacetamide deacetylase (esterase)
chrX_+_10294490 4.392 NM_001166635
NM_026524
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr2_-_66278870 4.255 NM_018733
Scn1a
sodium channel, voltage-gated, type I, alpha
chr1_+_174628164 4.202 NM_007768
Crp
C-reactive protein, pentraxin-related
chr16_+_3884618 4.065 NM_029090
Nat15
N-acetyltransferase 15 (GCN5-related, putative)
chr4_-_77857594 4.009 Ptprd
protein tyrosine phosphatase, receptor type, D
chr12_-_8505780 3.993 Rhob
ras homolog gene family, member B
chr16_+_22892156 3.980 Ahsg
alpha-2-HS-glycoprotein
chr1_-_195068455 3.968 NM_001044751
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
chr19_+_23216035 3.908 Klf9
Kruppel-like factor 9
chr14_-_19071459 3.890 NM_011584
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr2_+_131735663 3.882 NM_011170
Prnp
prion protein
chr14_+_60997104 3.860 NM_001164705
NM_028113
Fam123a

family with sequence similarity 123, member A

chr16_+_22892125 3.778 Ahsg
alpha-2-HS-glycoprotein
chr10_-_77927652 3.774 NM_172134
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr5_-_92757021 3.704 NM_008599
Cxcl9
chemokine (C-X-C motif) ligand 9
chr8_-_42127124 3.642 Mtus1
mitochondrial tumor suppressor 1
chr8_-_42127242 3.631 NM_001005865
Mtus1
mitochondrial tumor suppressor 1
chr12_-_105094033 3.600 Serpina1a
serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr4_-_41720928 3.587 NM_001164045
NM_001048179
NM_001164044
Ccl27a


chemokine (C-C motif) ligand 27A


chr4_-_126427788 3.583 Ncdn
neurochondrin
chr1_-_175266945 3.546 Cadm3
cell adhesion molecule 3
chr7_-_88851823 3.545 Homer2
homer homolog 2 (Drosophila)
chr8_-_95603838 3.545 NM_001081372
Ces1b
carboxylesterase 1B
chr1_-_93355838 3.544 Per2
period homolog 2 (Drosophila)
chr7_+_27620354 3.484 NM_007812
Cyp2a5
cytochrome P450, family 2, subfamily a, polypeptide 5
chr7_+_27092187 3.430 NM_009997
Cyp2a4
cytochrome P450, family 2, subfamily a, polypeptide 4
chr9_+_46721685 3.414 2900052N01Rik
RIKEN cDNA 2900052N01 gene
chr7_+_147949708 3.376 NM_021282
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr2_+_135883662 3.357 NM_029530
6330527O06Rik
RIKEN cDNA 6330527O06 gene
chr2_+_134611953 3.300 Plcb1
phospholipase C, beta 1
chr4_-_150418704 3.294 NM_011067
Per3
period homolog 3 (Drosophila)
chr1_+_10983542 3.249 NM_029525
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr19_-_34821529 3.236 NM_172838
Slc16a12
solute carrier family 16 (monocarboxylic acid transporters), member 12
chr15_-_8660393 3.225 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_+_56040193 3.181 Gpm6a
glycoprotein m6a
chr16_+_22892112 3.158 NM_013465
Ahsg
alpha-2-HS-glycoprotein
chr15_+_27396405 3.130 NM_020332
Ank
progressive ankylosis
chr4_+_84851440 3.100 Sh3gl2
SH3-domain GRB2-like 2
chr14_-_37948251 2.967 NM_078478
Ghitm
growth hormone inducible transmembrane protein
chr4_-_11892848 2.957 NM_001098231
Pdp1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_-_88851798 2.914 NM_001164086
NM_011983
Homer2

homer homolog 2 (Drosophila)

chr12_+_37968225 2.855 NM_178767
Tmem195
transmembrane protein 195
chr15_-_93167238 2.831 Yaf2
YY1 associated factor 2
chr7_+_27620380 2.774 Cyp2a4
Cyp2a5
cytochrome P450, family 2, subfamily a, polypeptide 4
cytochrome P450, family 2, subfamily a, polypeptide 5
chr14_+_60997156 2.763 Fam123a
family with sequence similarity 123, member A
chr4_-_134409149 2.755 Tmem57
transmembrane protein 57
chr10_-_63552994 2.754 NM_178678
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr9_+_121275947 2.732 NM_175114
Trak1
trafficking protein, kinesin binding 1
chr19_+_4510471 2.714 NM_001162946
Pcx
pyruvate carboxylase
chr15_-_93167308 2.672 NM_024189
Yaf2
YY1 associated factor 2
chr11_-_79344055 2.652 NM_001033711
NM_010161
NM_146023
Evi2a

Evi2b
ecotropic viral integration site 2a

ecotropic viral integration site 2b
chr4_-_134409199 2.625 Tmem57
transmembrane protein 57
chrX_+_33868347 2.569 NM_028894
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr6_-_13789847 2.565 NM_145066
Gpr85
G protein-coupled receptor 85
chr11_+_94189524 2.557 Ankrd40
ankyrin repeat domain 40
chr8_-_4105727 2.536 NM_026956
Cd209f
CD209f antigen
chr5_-_104419233 2.521 Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr1_+_136079079 2.455 Chi3l1
chitinase 3-like 1
chr9_+_124016886 2.454 NM_009915
Ccr2
chemokine (C-C motif) receptor 2
chr19_+_23215817 2.410 Klf9
Kruppel-like factor 9
chr6_-_40386107 2.402 NM_175528
E330009J07Rik
RIKEN cDNA E330009J07 gene
chr15_-_36937065 2.401 NM_026521
Zfp706
zinc finger protein 706
chr16_+_22920486 2.349 Fetub
fetuin beta
chr18_+_23962468 2.324 NM_153058
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr11_+_83522505 2.323 NM_007969
Expi
extracellular proteinase inhibitor
chr3_-_129035406 2.248 NM_007934
Enpep
glutamyl aminopeptidase
chr6_-_90612275 2.247 Iqsec1
IQ motif and Sec7 domain 1
chr8_-_93657840 2.215 Aktip
thymoma viral proto-oncogene 1 interacting protein
chr3_+_95985065 2.201 NM_022030
Sv2a
synaptic vesicle glycoprotein 2 a
chr2_+_118687703 2.196 NM_019826
Ivd
isovaleryl coenzyme A dehydrogenase
chr14_+_120724380 2.193 Mbnl2
muscleblind-like 2
chr8_+_56040080 2.192 NM_153581
Gpm6a
glycoprotein m6a
chrX_-_133275812 2.172 NM_001168226
NM_001168229
Morf4l2

mortality factor 4 like 2

chr3_-_96044172 2.172 NM_013549
NM_178212
Hist2h2aa1
Hist2h2aa2
histone cluster 2, H2aa1
histone cluster 2, H2aa2
chr3_+_129235336 2.159 Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr5_-_130363202 2.156 NM_024166
Chchd2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr9_-_107571304 2.156 Slc38a3
solute carrier family 38, member 3
chr12_-_79962445 2.151 NM_023721
Atp6v1d
ATPase, H+ transporting, lysosomal V1 subunit D
chr15_-_36937026 2.140 Zfp706
zinc finger protein 706
chr15_-_33617572 2.101 NM_001085421
Tspyl5
testis-specific protein, Y-encoded-like 5
chr1_-_18127131 2.085 NM_030033
Crisp4
cysteine-rich secretory protein 4
chr16_-_5013596 2.063 NM_133185
Rogdi
rogdi homolog (Drosophila)
chr4_-_134409254 2.031 NM_025382
Tmem57
transmembrane protein 57
chr9_-_40153864 2.024 Gramd1b
GRAM domain containing 1B
chr6_-_55124983 2.015 NM_009349
Inmt
indolethylamine N-methyltransferase
chr14_-_109313333 2.005 Slitrk1
SLIT and NTRK-like family, member 1
chr3_-_146433544 2.004 NM_001164199
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr9_-_106141043 1.996 Alas1
aminolevulinic acid synthase 1
chr18_+_37157533 1.985 NM_138661
Pcdha9
protocadherin alpha 9
chr2_+_103867951 1.974 NM_020593
NM_212433
Fbxo3

F-box protein 3

chr8_-_73987384 1.972 NM_022419
Abhd8
abhydrolase domain containing 8
chr18_+_44264117 1.945 NM_030061
Spink12
serine peptidase inhibitor, Kazal type 11
chr14_+_120674921 1.927 Mbnl2
muscleblind-like 2
chr5_-_124315478 1.920 NM_030701
Niacr1
niacin receptor 1
chr10_-_31165691 1.908 NM_009413
Tpd52l1
tumor protein D52-like 1
chr5_-_122017937 1.896


chr17_+_43938789 1.878 NM_207649
Rcan2
regulator of calcineurin 2
chr3_-_146433200 1.867 NM_001164198
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr14_+_120674933 1.847 Mbnl2
muscleblind-like 2
chr15_-_76137667 1.823 NM_153122
Oplah
5-oxoprolinase (ATP-hydrolysing)
chr4_-_47487233 1.810 NM_019998
Alg2
asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase)
chr10_+_90038471 1.808 NM_001177397
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr7_-_128217980 1.802 NM_030691
Igsf6
immunoglobulin superfamily, member 6
chr6_-_119305193 1.768 Adipor2
adiponectin receptor 2
chr5_+_67067359 1.760 NM_011670
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr2_+_103911166 1.718 NM_181858
Cd59b
CD59b antigen
chr5_-_89886732 1.677 NM_008096
Gc
group specific component
chr17_+_8476698 1.674 Brp44l
brain protein 44-like
chr15_-_88808967 1.661 NM_133241
Mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
chr6_-_148937854 1.661 Dennd5b
DENN/MADD domain containing 5B
chr2_-_79748552 1.647 NM_001009978
NM_001009979
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr1_-_132586370 1.603 Pfkfb2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr3_+_84756090 1.575 NM_080428
Fbxw7
F-box and WD-40 domain protein 7
chr17_+_26852581 1.538 NM_029870
A930001N09Rik
RIKEN cDNA A930001N09 gene
chr9_+_118949880 1.522 Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr16_+_17045284 1.512 Mapk1
mitogen-activated protein kinase 1
chr14_+_120674913 1.497 Mbnl2
muscleblind-like 2
chr10_-_87937335 1.481 Chpt1
choline phosphotransferase 1
chr4_-_47487166 1.478 Alg2
asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase)
chr19_+_23241546 1.465 Klf9
Kruppel-like factor 9
chr7_+_126669754 1.444 NM_178758
Acsm5
acyl-CoA synthetase medium-chain family member 5
chr11_-_6344445 1.436 NM_029938
H2afv
H2A histone family, member V
chr9_-_44728790 1.435 NM_013795
Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr12_-_104932866 1.434 NM_001164742
Serpina1f
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr17_+_43938887 1.428 Rcan2
regulator of calcineurin 2
chr15_-_36936955 1.412 Zfp706
zinc finger protein 706
chr14_+_79248971 1.407 NM_027906
NM_173758
1300010F03Rik

RIKEN cDNA 1300010F03 gene

chr2_-_91790504 1.405 NM_001166597
Dgkz
diacylglycerol kinase zeta
chr12_+_53800369 1.386 NM_198111
Akap6
A kinase (PRKA) anchor protein 6
chr17_+_70871444 1.382 NM_001128180
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr3_+_30692217 1.367 Sec62
SEC62 homolog (S. cerevisiae)
chr2_+_158328394 1.360 Adig
adipogenin
chr17_+_8476638 1.315 NM_018819
Brp44l
brain protein 44-like
chr18_-_35374531 1.296 Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr14_+_22838933 1.292 NM_028275
1700112E06Rik
RIKEN cDNA 1700112E06 gene
chr17_-_34999458 1.291 NM_001142706
NM_008198
Cfb

complement factor B

chr7_-_29910144 1.238 NM_009109
Ryr1
ryanodine receptor 1, skeletal muscle
chr10_+_66648458 1.238 Jmjd1c
jumonji domain containing 1C
chr6_-_40837492 1.226 NM_139296
Moxd2
monooxygenase, DBH-like 2
chr2_+_148624569 1.166 NM_009978
Cst8
cystatin 8 (cystatin-related epididymal spermatogenic)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
26.59 9.54e-03 GO:0042447 hormone catabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.38 8.72e-03 GO:0005615 extracellular space
2.16 1.26e-02 GO:0005626 insoluble fraction
1.99 1.62e-02 GO:0000267 cell fraction

Nothing significant found in function category.