• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: NFKB1_REL_RELA.p2

Z-value: 4.218

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_35399970	119.668		H2-D1	histocompatibility 2, D region locus 1
chr17_+_56092045	103.771	NM_015766	Ebi3	Epstein-Barr virus induced gene 3
chr17_+_35400056	103.072		H2-D1 H2-L	histocompatibility 2, D region locus 1 histocompatibility 2, D region
chr17_+_35400038	97.493	NM_010380	H2-D1	histocompatibility 2, D region locus 1
chr17_+_35400049	94.830		H2-D1	histocompatibility 2, D region locus 1
chr17_+_56092075	94.030		Ebi3	Epstein-Barr virus induced gene 3
chr13_+_43880475	88.929	NM_009856	Cd83	CD83 antigen
chr9_-_7872821	88.433		Birc3	baculoviral IAP repeat-containing 3
chr19_+_46380418	75.740	NM_001177370	Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
chr3_-_135354500	74.656	NM_008689	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr12_-_56593543	74.611		Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr19_+_46379216	74.517	NM_001177369	Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
chr8_-_26212203	74.215		Plekha2	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr12_-_56593566	72.004	NM_010907	Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr3_-_135354151	71.695		Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr7_+_26472526	70.684		Tgfb1	transforming growth factor, beta 1
chr7_+_31206749	70.415		Nfkbid	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr7_-_109398578	70.128	NM_019566	Rhog	ras homolog gene family, member G
chr6_+_29476655	69.054	NM_012057	Irf5	interferon regulatory factor 5
chr19_+_46380107	68.485	NM_019408	Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
chr8_-_26212614	65.659		Plekha2	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr18_-_4352916	63.606	NM_007746	Map3k8	mitogen-activated protein kinase kinase kinase 8
chr8_+_123260247	63.407	NM_008320	Irf8	interferon regulatory factor 8
chr19_-_46380070	62.456		4833438C02Rik	RIKEN cDNA 4833438C02 gene
chr17_-_34137221	59.120	NM_001001892	H2-K1	histocompatibility 2, K1, K region
chr11_-_83343962	57.516	NM_013653	Ccl5	chemokine (C-C motif) ligand 5
chr8_-_26212588	56.726		Plekha2	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr7_+_26472573	56.429		Tgfb1	transforming growth factor, beta 1
chr7_-_20214596	55.082	NM_009046	Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B
chr1_-_36330235	53.980	NM_153408	Neurl3	neuralized homolog 3 homolog (Drosophila)
chr8_-_26212242	52.085	NM_031257	Plekha2	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr9_-_7872896	51.051	NM_007464	Birc3	baculoviral IAP repeat-containing 3
chr4_-_151235758	50.128		Camta1	calmodulin binding transcription activator 1
chr1_+_64579559	49.024		Creb1	cAMP responsive element binding protein 1
chr1_-_167638156	47.508	NM_001038846 NM_178593	Rcsd1	RCSD domain containing 1
chr7_+_26471968	47.261	NM_011577	Tgfb1	transforming growth factor, beta 1
chr7_-_20408063	46.882		Bcl3	B-cell leukemia/lymphoma 3
chr10_-_12684064	43.453	NM_001163590 NM_001163591 NM_029075	Stx11	syntaxin 11
chr17_-_34137152	43.345		H2-K1	histocompatibility 2, K1, K region
chr7_-_20408020	43.255		Bcl3	B-cell leukemia/lymphoma 3
chr16_-_55822217	42.366	NM_001159394	Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr1_+_64579358	42.105	NM_001037726 NM_009952 NM_133828	Creb1	cAMP responsive element binding protein 1
chr18_+_60963495	41.608	NM_001042605 NM_010545	Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr5_+_91320265	40.581	NM_008176	Cxcl1	chemokine (C-X-C motif) ligand 1
chr7_-_51787440	40.351	NM_019866	Spib	Spi-B transcription factor (Spi-1/PU.1 related)
chr7_+_82600419	40.201	NM_029332	Akap13	A kinase (PRKA) anchor protein 13
chr7_+_25155455	40.116		Kcnn4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_167638124	40.021		Rcsd1	RCSD domain containing 1
chr11_-_23670766	39.098	NM_009044	Rel	reticuloendotheliosis oncogene
chr7_-_20408100	38.850	NM_033601	Bcl3	B-cell leukemia/lymphoma 3
chr16_-_55838747	38.440	NM_001159395 NM_030612	Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr16_-_55838834	38.364		Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr12_+_87027595	38.364	NM_016767	Batf	basic leucine zipper transcription factor, ATF-like
chr7_+_25155415	37.083		Kcnn4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr11_+_53583515	37.069	NM_001159393 NM_008390	Irf1	interferon regulatory factor 1
chrX_+_83115611	36.632	NM_001163539	5430427O19Rik	RIKEN cDNA 5430427O19 gene
chr9_-_110959905	36.240		Ccrl2	chemokine (C-C motif) receptor-like 2
chr11_+_32433265	36.027	NM_009288	Stk10	serine/threonine kinase 10
chrX_+_104479684	35.332	NM_001177782	Gpr174	G protein-coupled receptor 174
chr14_-_56209895	34.866	NM_001029855	Psme2	proteasome (prosome, macropain) 28 subunit, beta
chr10_-_12683885	34.538		Stx11	syntaxin 11
chr3_-_83645515	34.364	NM_011905	Tlr2	toll-like receptor 2
chr2_-_5635547	34.250	NM_177343	Camk1d	calcium/calmodulin-dependent protein kinase ID
chr5_-_124928243	33.841	NM_030259	Rilpl2	Rab interacting lysosomal protein-like 2
chr14_+_56503830	33.595		Khnyn	KH and NYN domain containing
chr3_-_83645460	33.516		Tlr2	toll-like receptor 2
chr2_-_26883441	33.457	NM_001177627 NM_172659	Slc2a6	solute carrier family 2 (facilitated glucose transporter), member 6
chr3_-_83645498	33.441		Tlr2	toll-like receptor 2
chr11_-_54769601	33.265		Tnip1	TNFAIP3 interacting protein 1
chr3_+_127492716	33.222	NM_145133	Tifa	TRAF-interacting protein with forkhead-associated domain
chr3_-_83645593	32.714		Tlr2	toll-like receptor 2
chr1_+_161974651	32.609		4930523C07Rik	RIKEN cDNA 4930523C07 gene
chr6_+_15670660	32.469	NM_175088	Mdfic	MyoD family inhibitor domain containing
chr9_-_85220730	32.333	NM_001160378 NM_001160379	Fam46a	family with sequence similarity 46, member A
chr1_+_89516886	31.920	NM_001110192 NM_001110193 NM_010566	Inpp5d	inositol polyphosphate-5-phosphatase D
chr8_-_107155195	31.903	NM_019662	Rrad	Ras-related associated with diabetes
chr8_-_107155164	31.728		Rrad	Ras-related associated with diabetes
chr5_+_30339682	31.560	NM_031168	Il6	interleukin 6
chr8_-_124956759	31.489	NM_007806	Cyba	cytochrome b-245, alpha polypeptide
chr5_-_92777875	31.484	NM_021274	Cxcl10	chemokine (C-X-C motif) ligand 10
chr17_+_35576081	31.400	NM_001198560 NM_001198561 NM_010394	H2-Q9 H2-Q7	histocompatibility 2, Q region locus 9 histocompatibility 2, Q region locus 7
chr17_-_34424623	31.170	NM_010378	H2-Aa	histocompatibility 2, class II antigen A, alpha
chr12_+_112404645	30.730	NM_001048206 NM_011632	Traf3	TNF receptor-associated factor 3
chr11_-_54776398	30.298	NM_021327	Tnip1	TNFAIP3 interacting protein 1
chr7_-_90803895	30.219		Il16	interleukin 16
chr14_-_62301012	30.157		Dleu2	deleted in lymphocytic leukemia, 2
chr11_-_83392109	29.622		Ccl9	chemokine (C-C motif) ligand 9
chr8_-_86566435	29.284	NM_016671	Il27ra	interleukin 27 receptor, alpha
chr17_+_34229284	28.744	NM_008206	H2-Oa	histocompatibility 2, O region alpha locus
chr10_-_18735154	28.302	NM_009397	Tnfaip3	tumor necrosis factor, alpha-induced protein 3
chr3_-_127599117	28.258	NM_027482	5730508B09Rik	RIKEN cDNA 5730508B09 gene
chr14_-_31439299	28.169		Prkcd	protein kinase C, delta
chr19_-_3903069	27.707		Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr13_+_51740804	27.436		Cks2	CDC28 protein kinase regulatory subunit 2
chr7_-_53176218	27.128	NM_001146346	Emp3	epithelial membrane protein 3
chr2_-_174264400	26.810	NM_022325	Ctsz	cathepsin Z
chr17_+_35530986	26.767	NM_023124	H2-Q8	histocompatibility 2, Q region locus 8
chr9_-_110959702	26.118	NM_017466	Ccrl2	chemokine (C-C motif) receptor-like 2
chr17_+_35516558	25.959	NM_001143689	H2-Gs10	MHC class I like protein GS10
chr18_+_50139080	25.936	NM_001177759 NM_001177760	Tnfaip8	tumor necrosis factor, alpha-induced protein 8
chr11_+_117710532	25.892	NM_001012273 NM_009689	Birc5	baculoviral IAP repeat-containing 5
chr13_+_51740600	25.713	NM_025415	Cks2	CDC28 protein kinase regulatory subunit 2
chr18_-_67884185	25.585	NM_001127177 NM_008977	Ptpn2	protein tyrosine phosphatase, non-receptor type 2
chr8_+_74121544	25.545	NM_001166213	Fam129c	family with sequence similarity 129, member C
chr9_-_40965718	25.485		Ubash3b	ubiquitin associated and SH3 domain containing, B
chr17_-_57367542	24.965	NM_009778	C3	complement component 3
chrX_+_104284572	24.938	NM_172435	P2ry10	purinergic receptor P2Y, G-protein coupled 10
chr1_+_161974503	24.908	NM_001162896	4930523C07Rik	RIKEN cDNA 4930523C07 gene
chr17_+_35187325	24.701		Clic1	chloride intracellular channel 1
chr14_+_56503783	24.697	NM_027143	Khnyn	KH and NYN domain containing
chr9_-_44334460	24.620	NM_007551	Cxcr5	chemokine (C-X-C motif) receptor 5
chr10_-_90545483	24.606	NM_001042558 NM_009684	Apaf1	apoptotic peptidase activating factor 1
chr11_-_54769546	24.511		Tnip1	TNFAIP3 interacting protein 1
chr14_-_56209708	24.468	NM_011190	Psme2 Psme2b-ps	proteasome (prosome, macropain) 28 subunit, beta protease (prosome, macropain) 28 subunit beta B, pseudogene
chr1_-_135975681	24.343	NM_007570	Btg2	B-cell translocation gene 2, anti-proliferative
chr13_-_112280018	24.273	NM_001122963 NM_028487	Gpbp1	GC-rich promoter binding protein 1
chr7_+_86058650	23.984	NM_020583	Isg20	interferon-stimulated protein
chr3_-_116126932	23.900	NM_001080818 NM_001173553	Cdc14a	CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr1_+_153418580	23.751		Fam129a	family with sequence similarity 129, member A
chr2_-_32243215	23.523		Lcn2	lipocalin 2
chr12_+_77471173	23.470	NM_178744	Zbtb1	zinc finger and BTB domain containing 1
chr5_+_91215126	23.353	NM_203320	Cxcl3	chemokine (C-X-C motif) ligand 3
chr1_+_161974815	23.321		4930523C07Rik	RIKEN cDNA 4930523C07 gene
chr11_+_100721765	23.147	NM_001164062	Stat5a	signal transducer and activator of transcription 5A
chr15_-_79572885	22.895	NM_194342	Sun2	Sad1 and UNC84 domain containing 2
chr11_-_83391984	22.855		Ccl9	chemokine (C-C motif) ligand 9
chr5_-_17341512	22.830		Cd36	CD36 antigen
chr12_+_112404563	22.775		Traf3	TNF receptor-associated factor 3
chr18_-_61195852	22.759	NM_009880	Cdx1	caudal type homeobox 1
chr9_-_44689356	22.689	NM_001081049	Mll1	myeloid/lymphoid or mixed-lineage leukemia 1
chr17_-_35137799	22.655		D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5
chr7_+_132695735	22.556		Il4ra	interleukin 4 receptor, alpha
chr11_-_84684177	22.485	NM_153144	Ggnbp2	gametogenetin binding protein 2
chr9_-_40965548	22.478	NM_176860	Ubash3b	ubiquitin associated and SH3 domain containing, B
chr6_+_42300005	22.350		Zyx	zyxin
chr6_-_124688630	22.321	NM_001077705	Ptpn6	protein tyrosine phosphatase, non-receptor type 6
chr10_-_90545406	22.105		Apaf1	apoptotic peptidase activating factor 1
chr12_+_110031520	22.083	NM_009537	Yy1	YY1 transcription factor
chr17_+_35187185	21.977	NM_033444	Clic1	chloride intracellular channel 1
chr10_-_44178474	21.972	NM_007548	Prdm1	PR domain containing 1, with ZNF domain
chr17_-_34999458	21.932	NM_001142706 NM_008198	Cfb	complement factor B
chr12_+_119082333	21.703	NM_146040	Cdca7l	cell division cycle associated 7 like
chr10_-_44178372	21.653		Prdm1	PR domain containing 1, with ZNF domain
chr15_+_78075220	21.514	NM_008677	Ncf4	neutrophil cytosolic factor 4
chr9_-_106101461	21.466	NM_026447	Ppm1m	protein phosphatase 1M
chr2_-_90420529	21.445		Ptprj	protein tyrosine phosphatase, receptor type, J
chr6_+_42299820	21.354	NM_011777	Zyx	zyxin
chr3_-_65762057	21.338	NM_019937	Ccnl1	cyclin L1
chr6_+_125045998	21.151	NM_145979	Chd4	chromodomain helicase DNA binding protein 4
chr17_-_35137278	21.123		D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5
chr2_+_164881126	21.111	NM_011611 NM_170702 NM_170703 NM_170704	Cd40	CD40 antigen
chr8_+_81033220	21.069	NM_029736	Slc10a7	solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr11_-_106134024	20.819	NM_001130187	Smarcd2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr8_-_84926440	20.784	NM_008357	Il15	interleukin 15
chr6_-_39156609	20.781		Jhdm1d	jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr4_-_149075697	20.680	NM_001029837	Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide
chr9_-_44688946	20.473		Mll1	myeloid/lymphoid or mixed-lineage leukemia 1
chr1_+_168931547	20.293	NM_001160261 NM_001160262 NM_175461	Fam78b	family with sequence similarity 78, member B
chr10_-_18731766	20.183	NM_001166402	Tnfaip3	tumor necrosis factor, alpha-induced protein 3
chr1_-_182743632	20.032	NM_008210	H3f3a	H3 histone, family 3A
chr7_+_132695758	19.982	NM_001008700	Il4ra	interleukin 4 receptor, alpha
chr17_-_35137291	19.922		D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5
chr10_+_79127318	19.907	NM_013591	Madcam1	mucosal vascular addressin cell adhesion molecule 1
chr11_-_117830554	19.502	NM_007707	Socs3	suppressor of cytokine signaling 3
chr14_-_77436363	19.316	NM_172488	9030625A04Rik	RIKEN cDNA 9030625A04 gene
chr4_+_43970559	18.921	NM_027450	Glipr2	GLI pathogenesis-related 2
chr1_+_161974709	18.857		4930523C07Rik	RIKEN cDNA 4930523C07 gene
chr3_-_51144470	18.700		Elf2	E74-like factor 2
chr5_-_17341534	18.684		Cd36	CD36 antigen
chr2_+_61431102	18.627	NM_001164071 NM_001164072	Tank	TRAF family member-associated Nf-kappa B activator
chr1_-_90598670	18.586	NM_177305	Arl4c	ADP-ribosylation factor-like 4C
chr3_+_94758056	18.578		Rfx5	regulatory factor X, 5 (influences HLA class II expression)
chr12_+_110031153	18.076		Yy1	YY1 transcription factor
chr2_-_90420626	17.920	NM_008982	Ptprj	protein tyrosine phosphatase, receptor type, J
chr11_-_69499014	17.914	NM_001159505 NM_023517	Tnfsf13	tumor necrosis factor (ligand) superfamily, member 13
chr7_+_16894925	17.886	NM_133234	Bbc3	BCL2 binding component 3
chr3_+_30993952	17.879	NM_001039090 NM_011386	Skil	SKI-like
chr11_-_117830455	17.733		Socs3	suppressor of cytokine signaling 3
chr8_+_47825098	17.567	NM_008391	Irf2	interferon regulatory factor 2
chr16_+_91547266	17.461	NM_008338	Ifngr2	interferon gamma receptor 2
chr2_-_32243258	17.452	NM_008491	Lcn2	lipocalin 2
chr6_+_134870680	17.398		Cdkn1b	cyclin-dependent kinase inhibitor 1B
chr4_-_133443662	17.230	NM_009097	Rps6ka1	ribosomal protein S6 kinase polypeptide 1
chr15_-_63829523	17.177		Fam49b	family with sequence similarity 49, member B
chr10_-_68815606	17.069	NM_007659	Cdk1	cyclin-dependent kinase 1
chr7_-_29551412	17.022		Nfkbib	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr17_+_35561811	16.998	NM_207648	H2-Q6	histocompatibility 2, Q region locus 6
chr2_+_120393393	16.892	NM_001177792 NM_001177793 NM_009222	Snap23	synaptosomal-associated protein 23
chr11_+_98799013	16.889	NM_001177302	Rara	retinoic acid receptor, alpha
chr19_+_10917005	16.837	NM_023044	Slc15a3	solute carrier family 15, member 3
chr8_+_47825072	16.676		Irf2	interferon regulatory factor 2
chr11_+_69393851	16.563	NM_001127233 NM_011640	Trp53	transformation related protein 53
chr12_+_113919213	16.488		Zbtb42	zinc finger and BTB domain containing 42
chr5_-_123438517	16.321	NM_001005866	Kdm2b	lysine (K)-specific demethylase 2B
chr17_-_35137690	16.150		D17H6S56E-5	DNA segment, Chr 17, human D6S56E 5
chrX_-_163768423	16.138	NM_133211	Tlr7	toll-like receptor 7
chr10_+_80392814	16.102	NM_008655	Gadd45b	growth arrest and DNA-damage-inducible 45 beta
chr15_-_97923632	16.002	NM_144851	Senp1	SUMO1/sentrin specific peptidase 1
chr10_+_7445797	15.958	NM_011835	Katna1	katanin p60 (ATPase-containing) subunit A1
chr4_-_142718290	15.803		Prdm2	PR domain containing 2, with ZNF domain

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.71	7.08e-25	GO:0060255	regulation of macromolecule metabolic process
1.83	1.26e-24	GO:0010468	regulation of gene expression
1.57	2.34e-24	GO:0044260	cellular macromolecule metabolic process
1.88	8.82e-24	GO:0051252	regulation of RNA metabolic process
1.67	1.74e-23	GO:0031323	regulation of cellular metabolic process
1.88	2.13e-23	GO:0006355	regulation of transcription, DNA-dependent
1.82	3.29e-23	GO:0010556	regulation of macromolecule biosynthetic process
1.78	7.89e-23	GO:0051171	regulation of nitrogen compound metabolic process
1.79	1.32e-22	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.77	1.68e-22	GO:0009889	regulation of biosynthetic process
1.78	1.89e-22	GO:0031326	regulation of cellular biosynthetic process
1.60	5.74e-22	GO:0019222	regulation of metabolic process
1.81	6.33e-22	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.50	2.30e-21	GO:0043170	macromolecule metabolic process
1.64	5.02e-21	GO:0080090	regulation of primary metabolic process
1.42	3.08e-20	GO:0044237	cellular metabolic process
1.41	3.71e-20	GO:0044238	primary metabolic process
1.97	4.24e-20	GO:0006351	transcription, DNA-dependent
1.97	5.38e-20	GO:0032774	RNA biosynthetic process
1.80	1.47e-19	GO:0016070	RNA metabolic process
2.35	3.90e-18	GO:0002376	immune system process
1.63	1.07e-17	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.70	1.09e-17	GO:0090304	nucleic acid metabolic process
1.74	1.97e-17	GO:0009059	macromolecule biosynthetic process
1.74	5.27e-17	GO:0034645	cellular macromolecule biosynthetic process
1.71	6.62e-17	GO:0010467	gene expression
1.60	1.93e-15	GO:0044249	cellular biosynthetic process
1.58	7.17e-15	GO:0009058	biosynthetic process
1.32	1.05e-14	GO:0008152	metabolic process
1.99	1.56e-14	GO:0010604	positive regulation of macromolecule metabolic process
2.27	2.86e-14	GO:0010628	positive regulation of gene expression
1.61	6.65e-14	GO:0048518	positive regulation of biological process
1.51	9.47e-14	GO:0006807	nitrogen compound metabolic process
1.91	1.39e-13	GO:0009893	positive regulation of metabolic process
1.52	1.64e-13	GO:0034641	cellular nitrogen compound metabolic process
1.62	1.78e-12	GO:0048522	positive regulation of cellular process
2.13	4.32e-12	GO:0010557	positive regulation of macromolecule biosynthetic process
2.08	4.98e-12	GO:0031328	positive regulation of cellular biosynthetic process
1.90	5.07e-12	GO:0031325	positive regulation of cellular metabolic process
2.06	8.04e-12	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.06	9.51e-12	GO:0009891	positive regulation of biosynthetic process
1.62	1.18e-11	GO:0048519	negative regulation of biological process
2.21	1.37e-11	GO:0045893	positive regulation of transcription, DNA-dependent
2.09	2.32e-11	GO:0051173	positive regulation of nitrogen compound metabolic process
2.77	2.38e-11	GO:0006955	immune response
2.18	3.84e-11	GO:0051254	positive regulation of RNA metabolic process
2.09	5.37e-11	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63	1.12e-10	GO:0048523	negative regulation of cellular process
1.94	3.02e-09	GO:0010605	negative regulation of macromolecule metabolic process
2.55	4.68e-09	GO:0002684	positive regulation of immune system process
2.23	4.91e-09	GO:0002682	regulation of immune system process
2.17	2.40e-08	GO:0045892	negative regulation of transcription, DNA-dependent
2.06	2.77e-08	GO:0010558	negative regulation of macromolecule biosynthetic process
1.85	3.23e-08	GO:0009892	negative regulation of metabolic process
1.88	5.03e-08	GO:0031324	negative regulation of cellular metabolic process
2.14	5.43e-08	GO:0051253	negative regulation of RNA metabolic process
2.07	7.80e-08	GO:0010629	negative regulation of gene expression
1.64	9.69e-08	GO:0006464	protein modification process
2.81	1.06e-07	GO:0001817	regulation of cytokine production
1.99	1.30e-07	GO:0009890	negative regulation of biosynthetic process
2.00	1.78e-07	GO:0031327	negative regulation of cellular biosynthetic process
2.36	2.07e-07	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
2.04	2.10e-07	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.61	2.51e-07	GO:0043412	macromolecule modification
2.01	5.68e-07	GO:0051172	negative regulation of nitrogen compound metabolic process
2.02	5.88e-07	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14	8.00e-07	GO:0009987	cellular process
2.48	1.03e-06	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.21	1.56e-06	GO:0050789	regulation of biological process
2.32	1.71e-06	GO:0032583	regulation of gene-specific transcription
1.63	2.75e-06	GO:0051239	regulation of multicellular organismal process
2.00	2.89e-06	GO:0070887	cellular response to chemical stimulus
2.07	3.01e-06	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.56	3.78e-06	GO:0048513	organ development
1.77	4.25e-06	GO:0010941	regulation of cell death
3.35	5.34e-06	GO:0001819	positive regulation of cytokine production
1.58	6.23e-06	GO:0006950	response to stress
2.81	6.38e-06	GO:0006954	inflammatory response
2.11	6.54e-06	GO:0006952	defense response
1.21	6.68e-06	GO:0050794	regulation of cellular process
1.77	7.22e-06	GO:0043067	regulation of programmed cell death
1.77	7.32e-06	GO:0042981	regulation of apoptosis
1.75	8.71e-06	GO:0050793	regulation of developmental process
1.19	1.23e-05	GO:0065007	biological regulation
2.38	1.74e-05	GO:0016568	chromatin modification
2.60	2.07e-05	GO:0050778	positive regulation of immune response
2.04	3.28e-05	GO:0008284	positive regulation of cell proliferation
1.38	3.36e-05	GO:0007275	multicellular organismal development
1.46	3.47e-05	GO:0044267	cellular protein metabolic process
1.55	3.62e-05	GO:0048583	regulation of response to stimulus
2.32	4.50e-05	GO:0050776	regulation of immune response
2.21	5.18e-05	GO:0009611	response to wounding
1.75	6.87e-05	GO:0042127	regulation of cell proliferation
1.69	7.07e-05	GO:0035556	intracellular signal transduction
1.36	7.45e-05	GO:0032502	developmental process
2.53	1.02e-04	GO:0051101	regulation of DNA binding
1.41	1.52e-04	GO:0048731	system development
2.18	1.55e-04	GO:0009968	negative regulation of signal transduction
2.57	1.90e-04	GO:0090046	regulation of transcription regulator activity
2.16	2.67e-04	GO:0006325	chromatin organization
1.38	2.80e-04	GO:0048856	anatomical structure development
2.57	3.10e-04	GO:0051090	regulation of sequence-specific DNA binding transcription factor activity
2.39	3.48e-04	GO:0045321	leukocyte activation
2.52	3.48e-04	GO:0043193	positive regulation of gene-specific transcription
2.28	3.81e-04	GO:0001775	cell activation
1.36	3.82e-04	GO:0016043	cellular component organization
2.25	3.93e-04	GO:0051098	regulation of binding
2.18	4.55e-04	GO:0002520	immune system development
1.71	4.89e-04	GO:2000026	regulation of multicellular organismal development
2.14	5.00e-04	GO:0007389	pattern specification process
2.07	5.20e-04	GO:0023057	negative regulation of signaling
2.06	5.65e-04	GO:0010648	negative regulation of cell communication
2.20	5.89e-04	GO:0048534	hemopoietic or lymphoid organ development
2.18	5.95e-04	GO:0007243	intracellular protein kinase cascade
2.18	5.95e-04	GO:0023014	signal transduction via phosphorylation event
1.47	6.03e-04	GO:0042221	response to chemical stimulus
4.76	6.50e-04	GO:0007249	I-kappaB kinase/NF-kappaB cascade
3.45	6.67e-04	GO:0002699	positive regulation of immune effector process
1.75	6.93e-04	GO:0048584	positive regulation of response to stimulus
1.34	9.26e-04	GO:0071840	cellular component organization or biogenesis
2.65	1.04e-03	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
2.81	1.05e-03	GO:0002252	immune effector process
2.87	1.60e-03	GO:0051251	positive regulation of lymphocyte activation
2.51	1.72e-03	GO:0070201	regulation of establishment of protein localization
3.28	1.72e-03	GO:0033157	regulation of intracellular protein transport
3.28	1.72e-03	GO:0046822	regulation of nucleocytoplasmic transport
1.98	2.86e-03	GO:0051247	positive regulation of protein metabolic process
2.80	2.86e-03	GO:0002764	immune response-regulating signaling pathway
3.18	2.94e-03	GO:0051222	positive regulation of protein transport
1.34	3.08e-03	GO:0019538	protein metabolic process
1.89	3.13e-03	GO:0051276	chromosome organization
2.48	3.15e-03	GO:0032582	negative regulation of gene-specific transcription
2.64	4.06e-03	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.54	4.69e-03	GO:0009966	regulation of signal transduction
2.77	5.45e-03	GO:0002757	immune response-activating signal transduction
1.48	5.73e-03	GO:0006996	organelle organization
2.64	5.87e-03	GO:0050867	positive regulation of cell activation
2.50	5.87e-03	GO:0051223	regulation of protein transport
2.09	6.04e-03	GO:0051707	response to other organism
1.69	6.30e-03	GO:0031399	regulation of protein modification process
3.37	6.40e-03	GO:0042306	regulation of protein import into nucleus
1.59	6.69e-03	GO:0006796	phosphate metabolic process
2.57	6.73e-03	GO:0002697	regulation of immune effector process
2.40	6.95e-03	GO:0034097	response to cytokine stimulus
1.58	7.35e-03	GO:0006793	phosphorus metabolic process
1.95	7.95e-03	GO:0032270	positive regulation of cellular protein metabolic process
1.38	8.11e-03	GO:0071842	cellular component organization at cellular level
2.28	8.12e-03	GO:0032880	regulation of protein localization
2.65	8.48e-03	GO:0002696	positive regulation of leukocyte activation
2.59	8.60e-03	GO:0031349	positive regulation of defense response
2.38	8.64e-03	GO:0051249	regulation of lymphocyte activation
1.59	9.08e-03	GO:0032268	regulation of cellular protein metabolic process
1.97	9.29e-03	GO:0051240	positive regulation of multicellular organismal process
3.26	1.12e-02	GO:0002819	regulation of adaptive immune response
1.84	1.19e-02	GO:0048585	negative regulation of response to stimulus
1.66	1.22e-02	GO:0045595	regulation of cell differentiation
3.22	1.34e-02	GO:0002221	pattern recognition receptor signaling pathway
1.36	1.34e-02	GO:0071841	cellular component organization or biogenesis at cellular level
1.45	1.39e-02	GO:0065009	regulation of molecular function
4.01	1.59e-02	GO:0090316	positive regulation of intracellular protein transport
3.27	1.85e-02	GO:0002224	toll-like receptor signaling pathway
1.54	1.89e-02	GO:0051246	regulation of protein metabolic process
3.15	1.89e-02	GO:0002758	innate immune response-activating signal transduction
1.84	1.99e-02	GO:0071310	cellular response to organic substance
3.94	2.03e-02	GO:0042108	positive regulation of cytokine biosynthetic process
2.39	2.11e-02	GO:0016570	histone modification
1.62	2.20e-02	GO:0009790	embryo development
1.59	2.54e-02	GO:0009888	tissue development
3.86	2.57e-02	GO:0032388	positive regulation of intracellular transport
3.19	2.64e-02	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
3.08	2.65e-02	GO:0002218	activation of innate immune response
1.99	2.68e-02	GO:0031401	positive regulation of protein modification process
1.80	2.75e-02	GO:0051704	multi-organism process
1.90	2.78e-02	GO:0009607	response to biotic stimulus
2.44	2.83e-02	GO:0002253	activation of immune response
2.48	2.91e-02	GO:0002521	leukocyte differentiation
2.35	2.91e-02	GO:0016569	covalent chromatin modification
1.83	2.93e-02	GO:0043069	negative regulation of programmed cell death
2.08	3.03e-02	GO:0018193	peptidyl-amino acid modification
3.61	3.10e-02	GO:0060326	cell chemotaxis
3.79	3.24e-02	GO:0002274	myeloid leukocyte activation
2.76	3.55e-02	GO:0032386	regulation of intracellular transport
1.37	3.93e-02	GO:0030154	cell differentiation
2.18	4.02e-02	GO:0002694	regulation of leukocyte activation
2.16	4.04e-02	GO:0050865	regulation of cell activation
1.82	4.05e-02	GO:0043066	negative regulation of apoptosis
3.21	4.39e-02	GO:0042035	regulation of cytokine biosynthetic process
3.21	4.39e-02	GO:0045619	regulation of lymphocyte differentiation
1.36	4.46e-02	GO:0048869	cellular developmental process
1.67	4.48e-02	GO:0019220	regulation of phosphate metabolic process
1.67	4.48e-02	GO:0051174	regulation of phosphorus metabolic process
4.97	4.48e-02	GO:0031056	regulation of histone modification
4.97	4.48e-02	GO:0032655	regulation of interleukin-12 production
6.28	4.50e-02	GO:0048535	lymph node development
1.79	4.87e-02	GO:0060548	negative regulation of cell death

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.55	5.20e-26	GO:0005634	nucleus
1.25	1.10e-20	GO:0005622	intracellular
1.24	1.67e-18	GO:0044424	intracellular part
1.30	7.48e-17	GO:0043231	intracellular membrane-bounded organelle
1.30	1.32e-16	GO:0043227	membrane-bounded organelle
1.26	7.38e-16	GO:0043229	intracellular organelle
1.26	1.70e-15	GO:0043226	organelle
1.73	2.85e-12	GO:0044428	nuclear part
2.01	3.66e-12	GO:0005654	nucleoplasm
2.24	9.65e-12	GO:0044451	nucleoplasm part
1.77	8.33e-11	GO:0031981	nuclear lumen
1.65	2.87e-09	GO:0070013	intracellular organelle lumen
1.65	3.36e-09	GO:0043233	organelle lumen
1.11	5.21e-09	GO:0005623	cell
1.11	5.21e-09	GO:0044464	cell part
1.63	1.01e-08	GO:0031974	membrane-enclosed lumen
1.38	4.71e-07	GO:0032991	macromolecular complex
1.42	8.50e-07	GO:0043234	protein complex
2.44	1.31e-06	GO:0005667	transcription factor complex
1.29	2.90e-05	GO:0044422	organelle part
1.29	3.34e-05	GO:0044446	intracellular organelle part
7.06	4.88e-04	GO:0031519	PcG protein complex
1.14	4.25e-03	GO:0005737	cytoplasm
1.40	1.77e-02	GO:0005829	cytosol
1.71	3.35e-02	GO:0009986	cell surface
2.09	3.66e-02	GO:0009897	external side of plasma membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.25	2.15e-20	GO:0005488	binding
1.44	1.18e-19	GO:0005515	protein binding
1.67	4.32e-16	GO:0003676	nucleic acid binding
1.81	4.43e-15	GO:0003677	DNA binding
2.20	2.99e-12	GO:0001071	nucleic acid binding transcription factor activity
2.20	2.99e-12	GO:0003700	sequence-specific DNA binding transcription factor activity
2.24	5.07e-11	GO:0043565	sequence-specific DNA binding
2.02	5.62e-11	GO:0030528	transcription regulator activity
3.03	1.43e-07	GO:0010843	promoter binding
2.91	3.00e-07	GO:0000975	regulatory region DNA binding
2.91	3.00e-07	GO:0001067	regulatory region nucleic acid binding
2.91	3.00e-07	GO:0044212	transcription regulatory region DNA binding
3.00	2.44e-06	GO:0005126	cytokine receptor binding
2.41	3.53e-06	GO:0008134	transcription factor binding
2.90	6.16e-06	GO:0005125	cytokine activity
6.06	3.43e-05	GO:0008009	chemokine activity
1.51	5.18e-05	GO:0046914	transition metal ion binding
5.35	6.71e-05	GO:0042379	chemokine receptor binding
2.57	1.41e-04	GO:0003682	chromatin binding
3.89	2.72e-04	GO:0003704	specific RNA polymerase II transcription factor activity
3.28	3.74e-04	GO:0019955	cytokine binding
2.80	6.22e-04	GO:0003702	RNA polymerase II transcription factor activity
3.23	8.86e-04	GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
1.50	1.02e-03	GO:0008270	zinc ion binding
2.05	3.71e-03	GO:0016564	transcription repressor activity
2.64	4.38e-03	GO:0003690	double-stranded DNA binding
1.99	6.29e-03	GO:0016563	transcription activator activity
2.92	1.28e-02	GO:0016566	specific transcriptional repressor activity
3.13	1.35e-02	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
2.25	1.59e-02	GO:0043566	structure-specific DNA binding
2.32	1.63e-02	GO:0001664	G-protein-coupled receptor binding
1.56	1.64e-02	GO:0019899	enzyme binding
1.71	2.32e-02	GO:0019904	protein domain specific binding