Motif ID: NKX2-3_NKX2-5.p2

Z-value: 0.871


Transcription factors associated with NKX2-3_NKX2-5.p2:

Gene SymbolEntrez IDGene Name
Nkx2-3 18089 NK2 transcription factor related, locus 3 (Drosophila)
Nkx2-5 18091 NK2 transcription factor related, locus 5 (Drosophila)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-3chr19_+_43686803-0.258.2e-04Click!
Nkx2-5chr17_-_26978355-0.181.5e-02Click!


Activity profile for motif NKX2-3_NKX2-5.p2.

activity profile for motif NKX2-3_NKX2-5.p2


Sorted Z-values histogram for motif NKX2-3_NKX2-5.p2

Sorted Z-values for motif NKX2-3_NKX2-5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-3_NKX2-5.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_44470218 11.395 Scd1
stearoyl-Coenzyme A desaturase 1
chr15_-_96861590 10.931 Slc38a4
solute carrier family 38, member 4
chr11_+_52202137 9.128 Vdac1
voltage-dependent anion channel 1
chr11_+_96212945 8.258 NM_134032
Hoxb2
homeobox B2
chr11_+_75578548 8.163 Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr2_+_35159780 8.138 Gsn
gelsolin
chr6_+_4484651 8.132 Col1a2
collagen, type I, alpha 2
chr2_+_125860377 7.895 NM_008008
Fgf7
fibroblast growth factor 7
chr19_-_44476302 7.835 Scd1
stearoyl-Coenzyme A desaturase 1
chr11_+_29607599 7.453 Rtn4
reticulon 4
chr1_+_45368443 7.288 Col3a1
collagen, type III, alpha 1
chr3_+_54165028 7.211 NM_001198765
NM_001198766
NM_015784
Postn


periostin, osteoblast specific factor


chr2_+_125860507 7.055 Fgf7
fibroblast growth factor 7
chr11_+_67013553 6.929 NM_030679
Myh1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr11_+_66984528 6.799 NM_001039545
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr7_-_56103389 6.509 Csrp3
cysteine and glycine-rich protein 3
chr7_-_56103405 6.470 NM_001198841
Csrp3
cysteine and glycine-rich protein 3
chr6_+_83290548 6.457 Mobkl1b
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr1_-_55135054 6.383 Hspd1
heat shock protein 1 (chaperonin)
chr6_+_4483741 6.248 Col1a2
collagen, type I, alpha 2
chr15_-_56526052 6.161 NM_008216
Has2
hyaluronan synthase 2
chr1_+_45368382 6.026 NM_009930
Col3a1
collagen, type III, alpha 1
chr17_-_48571942 5.787 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr17_-_48572043 5.783 NM_009694
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr10_-_85474581 5.695 NM_177772
Bpil2
bactericidal/permeability-increasing protein-like 2
chr1_-_165243777 5.570 NM_001025570
NM_011127
NM_175686
Prrx1


paired related homeobox 1


chr13_+_49639847 5.420 Aspn
asporin
chrX_+_154137114 5.208 Smpx
small muscle protein, X-linked
chr9_-_103256690 5.198 Cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chr11_-_119971500 5.107 Slc38a10
solute carrier family 38, member 10
chr8_+_131238027 4.838 Itgb1
integrin beta 1 (fibronectin receptor beta)
chr6_+_112223751 4.805 NM_144799
Lmcd1
LIM and cysteine-rich domains 1
chr10_-_116786025 4.737 Cpsf6
cleavage and polyadenylation specific factor 6
chr3_+_67696141 4.647 NM_001113419
NM_177585
Iqcj-schip1
Iqcj
IQ motif containing J-schwannomin interacting protein 1 read-through transcript
IQ motif containing J
chr19_-_55177562 4.587 Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr13_+_83643032 4.505 NM_001170537
NM_025282
Mef2c

myocyte enhancer factor 2C

chr9_+_92502076 4.474


chr3_+_159502646 4.449 NM_026582
Wls
wntless homolog (Drosophila)
chr9_+_51855254 4.418 NM_001104616
Rdx
radixin
chr16_+_45094383 4.353 Ccdc80
coiled-coil domain containing 80
chr5_+_104868321 4.311 Spp1
secreted phosphoprotein 1
chr19_+_10271150 4.302 Fads1
fatty acid desaturase 1
chr2_+_74707394 4.285 Mtx2
metaxin 2
chr17_-_14831058 4.275 Thbs2
thrombospondin 2
chrX_+_34337066 4.273 Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr6_-_99216494 4.017 NM_001197321
Foxp1
forkhead box P1
chr13_-_102453449 3.944 Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr9_-_66880619 3.892 Tpm1
tropomyosin 1, alpha
chr11_+_29618696 3.868 Rtn4
reticulon 4
chr9_+_108239210 3.864 Rhoa
ras homolog gene family, member A
chr13_+_49639799 3.846 NM_001172481
NM_025711
Aspn

asporin

chrX_-_156560678 3.840 Pdha1
pyruvate dehydrogenase E1 alpha 1
chrX_+_154137049 3.766 NM_025357
Smpx
small muscle protein, X-linked
chr5_-_122907269 3.574 Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr2_+_132673469 3.453 NM_025646
Crls1
cardiolipin synthase 1
chr17_-_14831095 3.448 Thbs2
thrombospondin 2
chr9_+_54758322 3.439 Ireb2
iron responsive element binding protein 2
chr6_+_54839147 3.417 Znrf2
zinc and ring finger 2
chr2_+_162760505 3.407


chr2_-_84490827 3.380 NM_001085448
NM_001085449
NM_001085450
NM_007615
Ctnnd1



catenin (cadherin associated protein), delta 1



chr4_+_140256449 3.347 Rcc2
regulator of chromosome condensation 2
chr2_+_170336930 3.333 Pfdn4
prefoldin 4
chr6_-_87793898 3.316 Cnbp
cellular nucleic acid binding protein
chr2_+_174171525 3.225 Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr11_-_75114563 3.183 Rpa1
replication protein A1
chr1_-_165243608 3.176 Prrx1
paired related homeobox 1
chr6_+_4490515 3.166 Col1a2
collagen, type I, alpha 2
chr3_+_68376289 3.161 NM_013928
Schip1
schwannomin interacting protein 1
chr5_-_89886732 3.155 NM_008096
Gc
group specific component
chr11_+_29618531 3.101 NM_024226
Rtn4
reticulon 4
chr11_-_86331141 3.095 Rps6kb1
ribosomal protein S6 kinase, polypeptide 1
chr10_-_117252126 3.087


chr2_+_34631438 3.082 Hspa5
heat shock protein 5
chr3_+_79690856 3.081 Fam198b
family with sequence similarity 198, member B
chr3_+_68376319 2.990 Schip1
schwannomin interacting protein 1
chr1_+_40082070 2.985 Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_+_174051459 2.950 Copa
coatomer protein complex subunit alpha
chr12_+_39510297 2.926 NM_001163154
Etv1
ets variant gene 1
chr1_-_180259336 2.903 Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr16_-_19706367 2.886 Lamp3
lysosomal-associated membrane protein 3
chr4_+_57907032 2.881 Akap2
A kinase (PRKA) anchor protein 2
chr6_-_52176102 2.856 Hoxa9
homeobox A9
chr8_-_37631772 2.850 Dlc1
deleted in liver cancer 1
chr13_-_74832039 2.824 Cast
calpastatin
chr8_-_71601126 2.809 Slc18a1
solute carrier family 18 (vesicular monoamine), member 1
chr1_+_40082201 2.784 Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
chr8_-_64381465 2.772 NM_001081390
Palld
palladin, cytoskeletal associated protein
chr15_-_81191176 2.769 NM_011399
Slc25a17
solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chrX_+_132424640 2.750 Bhlhb9
basic helix-loop-helix domain containing, class B9
chr2_-_84490666 2.738 NM_001085453
Ctnnd1
catenin (cadherin associated protein), delta 1
chr11_-_116712559 2.706 Srsf2
serine/arginine-rich splicing factor 2
chr1_+_40496493 2.697 NM_010743
Il1rl1
interleukin 1 receptor-like 1
chr18_+_37834003 2.673 Pcdhga3
protocadherin gamma subfamily A, 3
chr6_+_145882641 2.673 NM_010656
Sspn
sarcospan
chr16_-_11220854 2.661 Gspt1
G1 to S phase transition 1
chr7_+_31548774 2.638 NM_001166173
NM_001166174
NM_172899
Dmkn


dermokine


chr5_+_35341726 2.575 NM_001163512
Rgs12
regulator of G-protein signaling 12
chr18_+_38476622 2.573


chr7_+_134356373 2.564 Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_+_13501725 2.546 Vim
vimentin
chr13_+_40955500 2.513 NM_023887
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chrX_-_35774388 2.512 Lamp2
lysosomal-associated membrane protein 2
chr10_+_87323855 2.498 NM_001111274
NM_001111276
NM_184052
Igf1


insulin-like growth factor 1


chr5_-_137548123 2.493 NM_008871
Serpine1
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr5_-_114881393 2.450


chr6_-_136890189 2.415 NM_007486
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chrX_+_130385546 2.411 NM_022322
Tnmd
tenomodulin
chr19_-_47766512 2.372 NM_007732
Col17a1
collagen, type XVII, alpha 1
chr6_-_72383494 2.363 Mat2a
methionine adenosyltransferase II, alpha
chr10_-_88067758 2.349 NM_175418
Mybpc1
myosin binding protein C, slow-type
chr16_-_23520662 2.333 NM_008555
Masp1
mannan-binding lectin serine peptidase 1
chr9_+_92502908 2.329 Plod2
procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
chr10_+_56097078 2.326 NM_010288
Gja1
gap junction protein, alpha 1
chr5_-_100391613 2.322 Hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr2_+_138104219 2.306 NM_145534
Btbd3
BTB (POZ) domain containing 3
chr4_+_48572811 2.272 5730528L13Rik
RIKEN cDNA 5730528L13 gene
chr2_+_34631709 2.257 Hspa5
heat shock protein 5
chr9_+_5345475 2.255 NM_009808
Casp12
caspase 12
chr2_+_174171943 2.228


chr15_-_22644738 2.227 NM_001165971
Gm5803
predicted gene 5803
chr16_-_19706392 2.225 Lamp3
lysosomal-associated membrane protein 3
chr5_-_122907002 2.219 Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr5_-_136384495 2.182


chr13_+_16106279 2.168 NM_008380
Inhba
inhibin beta-A
chr3_+_123008796 2.148 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr5_-_122906470 2.136 Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr16_+_56477956 2.136 NM_001014399
NM_001014422
NM_001014423
NM_001014424
NM_178790
Abi3bp




ABI gene family, member 3 (NESH) binding protein




chr14_+_102237708 2.118 Lmo7
LIM domain only 7
chr12_+_33535650 2.117 Nampt
nicotinamide phosphoribosyltransferase
chr2_-_26923387 2.092 NM_001159602
Tmem8c
transmembrane protein 8C
chr1_+_40497472 2.084 NM_001025602
Il1rl1
interleukin 1 receptor-like 1
chr2_+_34631124 2.077 Hspa5
heat shock protein 5
chr16_-_19706433 2.065 NM_177356
Lamp3
lysosomal-associated membrane protein 3
chr19_-_5845001 2.050 Neat1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr13_-_104554635 2.044 NM_172592
Srsf12
serine/arginine-rich splicing factor 12
chr6_+_55027608 1.997 Gars
glycyl-tRNA synthetase
chr1_-_151808361 1.975 NM_008869
Pla2g4a
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr8_+_48907496 1.932 NM_001111318
Cldn24
claudin 22-like
chr3_-_57098670 1.923 Tm4sf1
transmembrane 4 superfamily member 1
chr11_-_86399926 1.923 Tmem49
transmembrane protein 49
chr19_+_55700193 1.898


chr4_+_6321713 1.888 Sdcbp
syndecan binding protein
chr19_-_5844533 1.877 Neat1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr15_+_78860043 1.857 H1f0
H1 histone family, member 0
chr13_+_55501008 1.851 NM_011392
Slc34a1
solute carrier family 34 (sodium phosphate), member 1
chr4_+_118906433 1.849 NM_001042411
Lepre1
leprecan 1
chr6_+_112409498 1.838 NM_007617
Cav3
caveolin 3
chr11_-_120668581 1.825 Fasn
fatty acid synthase
chr9_-_110649625 1.822 NM_011199
Pth1r
parathyroid hormone 1 receptor
chr1_+_137904795 1.799 NM_001160145
Tmem9
transmembrane protein 9
chr5_+_147760198 1.795 NM_025652
Gtf3a
general transcription factor III A
chr6_+_34659440 1.771 NM_145575
Cald1
caldesmon 1
chr7_-_149762551 1.751 H19
H19 fetal liver mRNA
chr13_-_115248787 1.747 Fst
follistatin
chr2_-_119916315 1.740 Ehd4
EH-domain containing 4
chr4_-_129055102 1.715 Zbtb8a
zinc finger and BTB domain containing 8a
chr1_+_158769044 1.704 NM_028333
Angptl1
angiopoietin-like 1
chr8_-_112103065 1.670 NM_017370
Hp
haptoglobin
chr1_+_51346086 1.669 Sdpr
serum deprivation response
chr5_+_52755183 1.642 Sod3
superoxide dismutase 3, extracellular
chr5_+_88354611 1.634 NM_007786
Csn3
casein kappa
chr2_+_13504271 1.628


chr6_+_112409684 1.624 Cav3
caveolin 3
chr11_+_72264668 1.619 Mybbp1a
MYB binding protein (P160) 1a
chr6_+_115372083 1.603 NM_011146
Pparg
peroxisome proliferator activated receptor gamma
chr9_-_79566271 1.594 NM_007730
Col12a1
collagen, type XII, alpha 1
chr11_+_96160484 1.587 NM_008269
Hoxb6
homeobox B6
chr14_-_73762840 1.579 Itm2b
integral membrane protein 2B
chr11_+_52202706 1.574 Vdac1
voltage-dependent anion channel 1
chr3_+_60432922 1.570 Mbnl1
muscleblind-like 1 (Drosophila)
chr11_+_79845841 1.565 Suz12
suppressor of zeste 12 homolog (Drosophila)
chr19_-_4877874 1.562 NM_013456
Actn3
actinin alpha 3
chr15_-_103045710 1.544 NM_001110216
NM_007626
Cbx5

chromobox homolog 5 (Drosophila HP1a)

chr4_+_57907600 1.523 Akap2
A kinase (PRKA) anchor protein 2
chr1_+_109319264 1.511 NM_027548
Serpinb7
serine (or cysteine) peptidase inhibitor, clade B, member 7
chr11_+_96160268 1.508 Hoxb6
homeobox B6
chr1_+_90003410 1.505 Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr5_-_136174262 1.501


chr6_-_136889984 1.501 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr1_-_172018982 1.499 NM_022563
Ddr2
discoidin domain receptor family, member 2
chr14_-_61877218 1.498 NM_011892
Sgcg
sarcoglycan, gamma (dystrophin-associated glycoprotein)
chr2_+_162758440 1.494 Srsf6
serine/arginine-rich splicing factor 6
chr9_-_78326946 1.494 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr5_-_108304062 1.490 NM_007964
Evi5
ecotropic viral integration site 5
chr11_-_74991244 1.486 Ovca2
candidate tumor suppressor in ovarian cancer 2
chrX_+_156278399 1.481 NM_001135728
Sh3kbp1
SH3-domain kinase binding protein 1
chr4_-_132383213 1.466 Ppp1r8
protein phosphatase 1, regulatory (inhibitor) subunit 8
chr5_-_17341534 1.465 Cd36
CD36 antigen
chr18_+_61085283 1.449 NM_177407
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr2_-_110203264 1.449 Fibin
fin bud initiation factor homolog (zebrafish)
chr2_+_35413977 1.439 NM_001114125
Dab2ip
disabled homolog 2 (Drosophila) interacting protein
chr4_+_8533630 1.438 Rab2a
RAB2A, member RAS oncogene family
chr2_+_109516053 1.433 NM_001048139
Bdnf
brain derived neurotrophic factor
chr15_-_96850752 1.432 Slc38a4
solute carrier family 38, member 4
chr17_-_14831233 1.427 Thbs2
thrombospondin 2
chr1_+_136186579 1.426 NM_031189
Myog
myogenin
chr2_+_173603706 1.420 Vapb
vesicle-associated membrane protein, associated protein B and C
chr11_+_51085400 1.418 Clk4
CDC like kinase 4
chr2_+_170336729 1.407 NM_001110152
Pfdn4
prefoldin 4
chr13_-_102462584 1.402 NM_001024955
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.23 1.87e-07 GO:0009888 tissue development
1.61 2.26e-07 GO:0048518 positive regulation of biological process
1.56 2.61e-07 GO:0032502 developmental process
1.64 4.37e-07 GO:0048522 positive regulation of cellular process
1.77 1.56e-06 GO:0048513 organ development
1.88 2.83e-06 GO:0009653 anatomical structure morphogenesis
1.56 4.76e-06 GO:0016043 cellular component organization
1.57 6.81e-06 GO:0048856 anatomical structure development
1.52 1.29e-05 GO:0071840 cellular component organization or biogenesis
1.47 1.33e-05 GO:0080090 regulation of primary metabolic process
1.52 1.55e-05 GO:0007275 multicellular organismal development
1.59 2.45e-05 GO:0048731 system development
1.57 7.10e-05 GO:0048519 negative regulation of biological process
1.41 7.17e-05 GO:0019222 regulation of metabolic process
1.44 1.05e-04 GO:0031323 regulation of cellular metabolic process
1.44 1.47e-04 GO:0060255 regulation of macromolecule metabolic process
1.59 1.60e-04 GO:0048523 negative regulation of cellular process
1.28 3.02e-04 GO:0044237 cellular metabolic process
2.13 8.89e-04 GO:0007155 cell adhesion
1.24 1.08e-03 GO:0008152 metabolic process
2.12 1.14e-03 GO:0022610 biological adhesion
4.60 1.56e-03 GO:0046545 development of primary female sexual characteristics
1.60 1.58e-03 GO:0065008 regulation of biological quality
2.79 2.14e-03 GO:0061061 muscle structure development
1.47 2.24e-03 GO:0010467 gene expression
1.26 2.42e-03 GO:0044238 primary metabolic process
1.70 2.70e-03 GO:0031325 positive regulation of cellular metabolic process
2.19 3.02e-03 GO:0072358 cardiovascular system development
2.19 3.02e-03 GO:0072359 circulatory system development
4.63 3.35e-03 GO:0008585 female gonad development
4.28 3.99e-03 GO:0046660 female sex differentiation
1.88 4.24e-03 GO:0048468 cell development
1.40 4.26e-03 GO:0009058 biosynthetic process
1.65 5.38e-03 GO:0009893 positive regulation of metabolic process
1.48 5.68e-03 GO:0051252 regulation of RNA metabolic process
1.14 5.99e-03 GO:0009987 cellular process
1.40 6.69e-03 GO:0044249 cellular biosynthetic process
1.56 9.97e-03 GO:0042221 response to chemical stimulus
2.11 1.03e-02 GO:0048646 anatomical structure formation involved in morphogenesis
2.10 1.20e-02 GO:0008284 positive regulation of cell proliferation
1.43 1.20e-02 GO:0010468 regulation of gene expression
1.85 1.24e-02 GO:0009790 embryo development
1.42 1.25e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.99 1.35e-02 GO:0009887 organ morphogenesis
2.77 1.47e-02 GO:0030036 actin cytoskeleton organization
3.08 1.70e-02 GO:0060537 muscle tissue development
4.64 1.82e-02 GO:0061039 ovum-producing ovary development
1.73 1.93e-02 GO:0050793 regulation of developmental process
1.29 1.96e-02 GO:0044260 cellular macromolecule metabolic process
3.16 1.97e-02 GO:0042692 muscle cell differentiation
1.78 2.09e-02 GO:0042127 regulation of cell proliferation
1.41 2.17e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.45 2.31e-02 GO:0006355 regulation of transcription, DNA-dependent
1.79 2.39e-02 GO:2000026 regulation of multicellular organismal development
2.10 2.45e-02 GO:0060548 negative regulation of cell death
2.50 2.59e-02 GO:0001501 skeletal system development
6.93 2.69e-02 GO:0031032 actomyosin structure organization
2.17 2.73e-02 GO:0048598 embryonic morphogenesis
1.74 2.75e-02 GO:0031324 negative regulation of cellular metabolic process
1.85 2.99e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.42 3.79e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.92 3.80e-02 GO:0048608 reproductive structure development
2.10 3.89e-02 GO:0043066 negative regulation of apoptosis
3.12 4.06e-02 GO:0045137 development of primary sexual characteristics
2.60 4.20e-02 GO:0030029 actin filament-based process
1.82 4.53e-02 GO:0051254 positive regulation of RNA metabolic process
1.70 4.61e-02 GO:0010941 regulation of cell death
4.25 4.64e-02 GO:0022602 ovulation cycle process
1.76 4.67e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.35 4.79e-02 GO:0010038 response to metal ion
1.42 4.93e-02 GO:0009059 macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.24 6.07e-10 GO:0044424 intracellular part
1.23 7.01e-10 GO:0005622 intracellular
1.30 4.48e-09 GO:0005737 cytoplasm
1.26 1.19e-08 GO:0043226 organelle
1.25 4.86e-08 GO:0043229 intracellular organelle
2.10 9.86e-07 GO:0005624 membrane fraction
1.92 1.08e-06 GO:0000267 cell fraction
2.03 2.90e-06 GO:0005626 insoluble fraction
1.41 4.01e-06 GO:0044422 organelle part
1.24 5.03e-06 GO:0043227 membrane-bounded organelle
1.24 8.70e-06 GO:0043231 intracellular membrane-bounded organelle
1.32 1.48e-05 GO:0044444 cytoplasmic part
4.64 3.70e-05 GO:0030017 sarcomere
4.19 3.76e-05 GO:0030016 myofibril
4.31 5.20e-05 GO:0044449 contractile fiber part
1.38 5.34e-05 GO:0044446 intracellular organelle part
3.85 1.46e-04 GO:0043292 contractile fiber
1.85 2.53e-04 GO:0044421 extracellular region part
1.40 3.91e-04 GO:0032991 macromolecular complex
1.64 5.45e-04 GO:0005829 cytosol
1.91 1.73e-03 GO:0005615 extracellular space
1.41 2.35e-03 GO:0043234 protein complex
1.28 2.52e-03 GO:0005634 nucleus
1.42 6.48e-03 GO:0043228 non-membrane-bounded organelle
1.42 6.48e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.51 7.82e-03 GO:0031974 membrane-enclosed lumen
1.90 8.61e-03 GO:0030054 cell junction
1.51 8.94e-03 GO:0070013 intracellular organelle lumen
1.51 9.62e-03 GO:0043233 organelle lumen
1.67 1.45e-02 GO:0005654 nucleoplasm
2.52 1.49e-02 GO:0005911 cell-cell junction
4.25 1.51e-02 GO:0031674 I band
1.08 2.54e-02 GO:0005623 cell
1.08 2.54e-02 GO:0044464 cell part
1.78 4.07e-02 GO:0044451 nucleoplasm part
1.44 4.39e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.49 1.07e-13 GO:0005515 protein binding
1.25 1.90e-11 GO:0005488 binding
2.81 1.76e-05 GO:0016564 transcription repressor activity
1.99 5.05e-05 GO:0019899 enzyme binding
1.96 4.94e-04 GO:0001071 nucleic acid binding transcription factor activity
1.96 4.94e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.83 1.02e-03 GO:0030528 transcription regulator activity
1.99 1.53e-03 GO:0043565 sequence-specific DNA binding
2.60 4.00e-03 GO:0019901 protein kinase binding
6.93 5.74e-03 GO:0005200 structural constituent of cytoskeleton
2.72 9.61e-03 GO:0003682 chromatin binding
11.42 1.73e-02 GO:0034185 apolipoprotein binding
1.93 3.25e-02 GO:0008092 cytoskeletal protein binding
2.26 3.31e-02 GO:0019900 kinase binding
2.13 4.05e-02 GO:0032403 protein complex binding