Motif ID: NKX3-2.p2

Z-value: 1.217


Transcription factors associated with NKX3-2.p2:

Gene SymbolEntrez IDGene Name
Nkx3-2 12020 NK3 homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx3-2chr5_-_42155453-0.257.6e-04Click!


Activity profile for motif NKX3-2.p2.

activity profile for motif NKX3-2.p2


Sorted Z-values histogram for motif NKX3-2.p2

Sorted Z-values for motif NKX3-2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45401303 18.343 Col3a1
collagen, type III, alpha 1
chr1_+_45401659 17.612 Col3a1
collagen, type III, alpha 1
chr6_+_4484651 16.835 Col1a2
collagen, type I, alpha 2
chr15_+_54402988 10.493 Mal2
mal, T-cell differentiation protein 2
chr1_-_45559866 9.969 Col5a2
collagen, type V, alpha 2
chr1_-_45559904 9.677 Col5a2
collagen, type V, alpha 2
chr9_-_45743950 9.647 Tagln
transgelin
chrX_+_10062237 9.162 NM_019634
Tspan7
tetraspanin 7
chr1_-_170362298 8.959 Pbx1
pre B-cell leukemia transcription factor 1
chr9_-_45744036 8.828 NM_011526
Tagln
transgelin
chr19_-_34329804 8.354 NM_007392
Acta2
actin, alpha 2, smooth muscle, aorta
chr19_+_27291897 8.340 Vldlr
very low density lipoprotein receptor
chr8_+_11443165 7.969 Col4a2
collagen, type IV, alpha 2
chr3_+_121426422 7.869 NM_010171
F3
coagulation factor III
chr9_-_66880619 7.814 Tpm1
tropomyosin 1, alpha
chr8_-_64381465 7.805 NM_001081390
Palld
palladin, cytoskeletal associated protein
chr19_+_27292039 7.796 Vldlr
very low density lipoprotein receptor
chr15_-_78236262 7.429 NM_009437
Tst
thiosulfate sulfurtransferase, mitochondrial
chr18_-_46887869 7.285 NM_033037
Cdo1
cysteine dioxygenase 1, cytosolic
chr15_+_75427044 7.276 NM_026730
Gpihbp1
GPI-anchored HDL-binding protein 1
chr16_-_85080242 7.175 App
amyloid beta (A4) precursor protein
chr18_+_37979199 7.100 NM_033583
Pcdhgb4
Pcdhgc5
protocadherin gamma subfamily B, 4
protocadherin gamma subfamily C, 5
chr11_+_54716354 6.980 NM_001083929
NM_008161
Gpx3

glutathione peroxidase 3

chr6_-_124586102 6.959 NM_173864
Gm5077
predicted gene 5077
chr18_+_37979242 6.920 Pcdhgc5
protocadherin gamma subfamily C, 5
chr17_-_57367499 6.838 C3
complement component 3
chr15_+_54402914 6.819 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr11_+_54716439 6.757 Gpx3
glutathione peroxidase 3
chr6_+_4455686 6.636 NM_007743
Col1a2
collagen, type I, alpha 2
chr17_-_57367542 6.628 NM_009778
C3
complement component 3
chr15_-_101834741 6.503 Krt8
keratin 8
chr12_-_11443284 6.459 NM_012038
Vsnl1
visinin-like 1
chr15_-_101834746 6.413 NM_031170
Krt8
keratin 8
chr5_+_67067497 6.337 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr2_-_165980462 6.197 Sulf2
sulfatase 2
chr7_-_148086285 6.175 Cox8b
cytochrome c oxidase, subunit VIIIb
chr15_-_101834744 6.157 Krt8
keratin 8
chr4_+_41774206 6.142 NM_011335
NM_001193668
NM_001193666
NM_023052
Ccl21b
Gm10591
Gm13304
Ccl21a
Ccl21c
chemokine (C-C motif) ligand 21B (leucine)
predicted gene 10591
predicted gene 13304
chemokine (C-C motif) ligand 21A (serine)
chemokine (C-C motif) ligand 21C (leucine)
chr5_+_67067359 6.123 NM_011670
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr15_-_101834713 6.095 Krt8
keratin 8
chr7_+_3289029 6.089 NM_001093764
Myadm
myeloid-associated differentiation marker
chr6_-_92484838 6.050 NM_001134459
Prickle2
prickle homolog 2 (Drosophila)
chr1_-_45560001 6.038 NM_007737
Col5a2
collagen, type V, alpha 2
chr9_-_66896961 6.019 Tpm1
tropomyosin 1, alpha
chr15_+_78860043 6.000 H1f0
H1 histone family, member 0
chr17_-_24769569 5.972 NM_001039363
NM_011647
Tsc2

tuberous sclerosis 2

chr7_-_133819870 5.938 NM_133670
Sult1a1
sulfotransferase family 1A, phenol-preferring, member 1
chr17_-_24769511 5.921 Tsc2
tuberous sclerosis 2
chr10_+_96945057 5.850 Dcn
decorin
chr7_+_137789668 5.844 Tacc2
transforming, acidic coiled-coil containing protein 2
chr17_-_24769539 5.834 Tsc2
tuberous sclerosis 2
chr6_-_87285690 5.829 NM_054041
Antxr1
anthrax toxin receptor 1
chr17_+_43526389 5.771 NM_001081178
Gpr116
G protein-coupled receptor 116
chr12_-_112615555 5.770 Cdc42bpb
CDC42 binding protein kinase beta
chr4_-_42787449 5.762 NM_001193667
NM_011124
Gm1987
Ccl21a
predicted gene 1987
chemokine (C-C motif) ligand 21A (serine)
chr4_+_42231042 5.751 NM_001193667
NM_011124
Gm1987
Ccl21a
predicted gene 1987
chemokine (C-C motif) ligand 21A (serine)
chr4_-_42393043 5.708 NM_011335
NM_001193668
NM_001193666
NM_023052
Ccl21b
Gm10591
Gm13304
Ccl21a
Ccl21c
chemokine (C-C motif) ligand 21B (leucine)
predicted gene 10591
predicted gene 13304
chemokine (C-C motif) ligand 21A (serine)
chemokine (C-C motif) ligand 21C (leucine)
chr7_-_52317768 5.677 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr2_+_132607432 5.413 Chgb
chromogranin B
chr14_+_102237708 5.396 Lmo7
LIM domain only 7
chr2_+_132607408 5.379 Chgb
chromogranin B
chr8_+_114464651 5.288


chr2_+_132607398 5.261 Chgb
chromogranin B
chr6_-_21802087 5.251 Tspan12
tetraspanin 12
chr12_-_73509925 5.244 NM_153457
Rtn1
reticulon 1
chr15_+_3220999 5.190 Sepp1
selenoprotein P, plasma, 1
chr15_+_3220766 5.141 NM_001042613
NM_001042614
NM_009155
Sepp1


selenoprotein P, plasma, 1


chr19_-_29101759 5.139


chr15_-_34608458 5.101 NM_145469
Nipal2
NIPA-like domain containing 2
chr1_-_45559700 5.028 Col5a2
collagen, type V, alpha 2
chr5_-_44485951 4.999 NM_001163578
NM_001163581
NM_001163582
NM_001163583
NM_001163584
NM_001163585
Prom1





prominin 1





chr12_+_118754951 4.998 NM_175930
Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr15_+_3220994 4.945 Sepp1
selenoprotein P, plasma, 1
chr4_-_4065585 4.867 NM_001002927
Penk
preproenkephalin
chr15_+_78860623 4.827


chr7_-_30954705 4.766 NM_011980
Zfp146
zinc finger protein 146
chr16_+_35002066 4.753 Mylk
myosin, light polypeptide kinase
chr15_+_91958558 4.731 NM_007727
Cntn1
contactin 1
chr11_+_3414983 4.683 Selm
selenoprotein M
chr19_-_44471675 4.651 Scd1
stearoyl-Coenzyme A desaturase 1
chr6_+_71657791 4.622 NM_178608
Reep1
receptor accessory protein 1
chr2_+_167514460 4.599 Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr12_+_110779204 4.598 Meg3
maternally expressed 3
chr19_-_5844533 4.591 Neat1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr9_-_66896992 4.558 Tpm1
tropomyosin 1, alpha
chr6_-_124761078 4.557 Tpi1
triosephosphate isomerase 1
chr3_-_81878554 4.544 NM_001161796
NM_017469
Gucy1b3

guanylate cyclase 1, soluble, beta 3

chr10_-_76188683 4.536 NM_009933
Col6a1
collagen, type VI, alpha 1
chr8_+_56040553 4.528 Gpm6a
glycoprotein m6a
chr1_-_170362388 4.517 NM_008783
NM_183355
Pbx1

pre B-cell leukemia transcription factor 1

chr1_-_163181313 4.457 Prdx6
peroxiredoxin 6
chr5_+_67067477 4.446 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr11_-_70468061 4.441 Pfn1
profilin 1
chr6_+_17256415 4.427 Cav1
caveolin 1, caveolae protein
chr8_+_126177709 4.382 NM_133955
Rhou
ras homolog gene family, member U
chr9_+_43877511 4.374 NM_016808
Usp2
ubiquitin specific peptidase 2
chr11_+_3414884 4.353 Selm
selenoprotein M
chr10_-_127935725 4.350 NM_172259
Myl6b
myosin, light polypeptide 6B
chr2_+_167514414 4.331 NM_009883
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr19_-_38199291 4.323 NM_011255
Rbp4
retinol binding protein 4, plasma
chr9_+_106350967 4.280 NM_029631
Abhd14b
abhydrolase domain containing 14b
chr9_+_75192367 4.263 Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr6_+_17256383 4.261 Cav1
caveolin 1, caveolae protein
chr4_-_60083171 4.256 Mup7
Mup1
major urinary protein 7
major urinary protein 1
chr15_+_101933364 4.244 NM_153533
Tenc1
tensin like C1 domain-containing phosphatase
chr2_+_164312023 4.234 Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_-_5845001 4.224 Neat1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr2_+_84903869 4.205 Tnks1bp1
tankyrase 1 binding protein 1
chr16_+_56477956 4.193 NM_001014399
NM_001014422
NM_001014423
NM_001014424
NM_178790
Abi3bp




ABI gene family, member 3 (NESH) binding protein




chr2_+_164388211 4.170 NM_026323
Wfdc2
WAP four-disulfide core domain 2
chr11_-_70468019 4.154 Pfn1
profilin 1
chr6_-_137468412 4.113 Eps8
epidermal growth factor receptor pathway substrate 8
chr2_+_132607013 4.074 NM_007694
Chgb
chromogranin B
chr11_-_74424353 4.072 Rap1gap2
RAP1 GTPase activating protein 2
chr12_-_73509668 4.038 Rtn1
reticulon 1
chr13_+_46597448 4.033 Cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr13_+_46597271 4.033 NM_026056
Cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr1_-_93355893 4.027 NM_011066
Per2
period homolog 2 (Drosophila)
chr7_-_108986589 4.013 NM_010567
Inppl1
inositol polyphosphate phosphatase-like 1
chr16_-_45844409 4.010 NM_153412
Phldb2
pleckstrin homology-like domain, family B, member 2
chr18_+_37915375 3.988 NM_033594
Pcdhga11
protocadherin gamma subfamily A, 11
chr2_+_35137898 3.987 NM_146120
Gsn
gelsolin
chr7_-_108986297 3.980 NM_001122739
Inppl1
inositol polyphosphate phosphatase-like 1
chr2_+_74543545 3.960 NM_008276
Hoxd8
homeobox D8
chr8_+_56040445 3.958 Gpm6a
glycoprotein m6a
chr6_+_17256369 3.957 NM_007616
Cav1
caveolin 1, caveolae protein
chr15_-_93426312 3.913 NM_001033217
Prickle1
prickle homolog 1 (Drosophila)
chr11_-_70468130 3.913 NM_011072
Pfn1
profilin 1
chr11_+_3414792 3.900 Selm
selenoprotein M
chr9_-_21571635 3.897 Kank2
KN motif and ankyrin repeat domains 2
chr19_-_38199036 3.890 Rbp4
retinol binding protein 4, plasma
chr7_-_74904546 3.863 NM_183312
NM_201639
NM_207663
Synm


synemin, intermediate filament protein


chrM_+_12383 3.831


chr9_-_95745663 3.821 NM_001033210
Pls1
plastin 1 (I-isoform)
chr18_-_33623287 3.818 NM_053078
D0H4S114
DNA segment, human D4S114
chr6_+_7505070 3.807 NM_009311
Tac1
tachykinin 1
chrX_+_70728939 3.798 NM_007542
Bgn
biglycan
chr10_-_70622370 3.776 NM_031397
Bicc1
bicaudal C homolog 1 (Drosophila)
chr7_+_120909625 3.774 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr15_-_34608600 3.764 Nipal2
NIPA-like domain containing 2
chr6_+_117118552 3.752 NM_001012477
NM_013655
NM_021704
Cxcl12


chemokine (C-X-C motif) ligand 12


chr4_+_104830022 3.739 Ppap2b
phosphatidic acid phosphatase type 2B
chr9_-_66897015 3.701 NM_001164248
NM_001164249
NM_001164250
NM_001164251
NM_001164255
NM_024427
Tpm1





tropomyosin 1, alpha





chr7_-_148086341 3.700 NM_007751
Cox8b
cytochrome c oxidase, subunit VIIIb
chr2_+_167514489 3.695 Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr5_-_24107718 3.680 NM_025891
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr9_-_49311823 3.674 Ncam1
neural cell adhesion molecule 1
chr12_-_87419813 3.666 NM_009368
Tgfb3
transforming growth factor, beta 3
chr7_+_112788972 3.665 Fxc1
fractured callus expressed transcript 1
chr1_-_176851918 3.659 Grem2
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr4_+_104829867 3.653 Ppap2b
phosphatidic acid phosphatase type 2B
chr3_+_52845429 3.621 NM_175386
Lhfp
lipoma HMGIC fusion partner
chr9_-_110649625 3.617 NM_011199
Pth1r
parathyroid hormone 1 receptor
chr19_+_3205598 3.615


chr15_+_6336747 3.600 NM_001037905
NM_001102400
NM_023118
Dab2


disabled homolog 2 (Drosophila)


chr2_+_10075220 3.572 Itih5
inter-alpha (globulin) inhibitor H5
chr10_+_21712008 3.562 NM_001161849
Sgk1
serum/glucocorticoid regulated kinase 1
chr8_+_46970814 3.562 NM_016798
Pdlim3
PDZ and LIM domain 3
chr4_-_63681749 3.561 NM_011607
Tnc
tenascin C
chr7_-_133943848 3.555 NM_001177308
Aldoa
aldolase A, fructose-bisphosphate
chr7_-_104566013 3.549 NM_009381
Thrsp
thyroid hormone responsive SPOT14 homolog (Rattus)
chr7_+_112788953 3.532 Fxc1
fractured callus expressed transcript 1
chr9_+_46036788 3.518 Apoa1
apolipoprotein A-I
chr10_+_87321789 3.498 NM_001111275
NM_010512
Igf1

insulin-like growth factor 1

chr7_+_52105323 3.496 Akt1s1
AKT1 substrate 1 (proline-rich)
chr9_-_105372402 3.493 Atp2c1
ATPase, Ca++-sequestering
chr3_-_143867852 3.455 Lmo4
LIM domain only 4
chr12_-_73509537 3.454 Rtn1
reticulon 1
chr8_+_97296066 3.451 NM_009142
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr11_+_32183671 3.450 NM_001083955
NM_008218
Hba-a2
Hba-a1
hemoglobin alpha, adult chain 2
hemoglobin alpha, adult chain 1
chr6_+_4483741 3.423 Col1a2
collagen, type I, alpha 2
chr7_-_135073577 3.406 Prss8
protease, serine, 8 (prostasin)
chr7_-_135073508 3.404 Prss8
protease, serine, 8 (prostasin)
chr7_+_27904981 3.391 Cyp2f2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr1_+_72757813 3.386 NM_009084
Rpl37a
ribosomal protein L37a
chr12_+_30622876 3.359 NM_181395
Pxdn
peroxidasin homolog (Drosophila)
chr2_+_136539202 3.358 Snap25
synaptosomal-associated protein 25
chr7_-_135073600 3.358 Prss8
protease, serine, 8 (prostasin)
chr6_+_30589440 3.355 Cpa1
carboxypeptidase A1
chr19_-_38199267 3.347 Rbp4
retinol binding protein 4, plasma
chr10_-_126648509 3.347 NM_054097
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr7_-_28338127 3.346 NM_011116
Pld3
phospholipase D family, member 3
chr10_+_58684631 3.336 NM_172939
Ankrd57
ankyrin repeat domain 57
chr3_-_87067445 3.335 NM_030707
Fcrls
Fc receptor-like S, scavenger receptor
chr3_-_143868114 3.310 Lmo4
LIM domain only 4
chr7_-_135073617 3.310 NM_133351
Prss8
protease, serine, 8 (prostasin)
chr8_+_122516412 3.305 Crispld2
cysteine-rich secretory protein LCCL domain containing 2
chr9_+_122076647 3.279


chr3_-_98662116 3.268 Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr8_+_114464639 3.262 Gabarapl2
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
chr5_+_136514365 3.243 NM_175309
Upk3b
uroplakin 3B
chr1_-_135817945 3.216 NM_054077
Prelp
proline arginine-rich end leucine-rich repeat
chr1_+_173367685 3.213 NM_172647
F11r
F11 receptor
chr7_+_135390325 3.202 NM_009365
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr2_+_169459145 3.189 NM_080455
Tshz2
teashirt zinc finger family member 2
chr8_-_13494457 3.187 NM_019521
Gas6
growth arrest specific 6
chr17_+_34400152 3.175 NM_207105
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr18_-_33623400 3.168 NM_001109989
D0H4S114
DNA segment, human D4S114
chr17_-_56249206 3.161 NM_020568
Plin4
perilipin 4
chr10_+_87322774 3.158 Igf1
insulin-like growth factor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.49 3.20e-17 GO:0032502 developmental process
1.54 1.36e-16 GO:0048856 anatomical structure development
1.56 8.46e-16 GO:0048731 system development
1.48 7.23e-15 GO:0007275 multicellular organismal development
1.64 4.69e-14 GO:0065008 regulation of biological quality
1.44 1.43e-13 GO:0051179 localization
1.47 1.25e-12 GO:0048518 positive regulation of biological process
1.43 5.82e-11 GO:0016043 cellular component organization
1.46 7.53e-11 GO:0048522 positive regulation of cellular process
1.43 2.02e-10 GO:0051234 establishment of localization
1.43 3.43e-10 GO:0006810 transport
1.39 1.58e-09 GO:0071840 cellular component organization or biogenesis
1.62 2.71e-09 GO:0009653 anatomical structure morphogenesis
1.41 4.42e-09 GO:0019538 protein metabolic process
1.66 4.71e-09 GO:0007399 nervous system development
1.69 9.71e-09 GO:0010646 regulation of cell communication
1.56 4.38e-08 GO:0023051 regulation of signaling
1.77 4.80e-08 GO:0051128 regulation of cellular component organization
1.99 6.79e-08 GO:0072358 cardiovascular system development
1.99 6.79e-08 GO:0072359 circulatory system development
1.45 1.49e-07 GO:0048869 cellular developmental process
1.42 2.27e-07 GO:0044267 cellular protein metabolic process
1.45 2.88e-07 GO:0030154 cell differentiation
1.50 6.32e-07 GO:0048583 regulation of response to stimulus
1.51 1.17e-06 GO:0051239 regulation of multicellular organismal process
1.83 1.42e-06 GO:0016192 vesicle-mediated transport
1.38 1.93e-06 GO:0048519 negative regulation of biological process
1.18 1.97e-06 GO:0008152 metabolic process
1.71 3.82e-06 GO:0048584 positive regulation of response to stimulus
1.56 4.84e-06 GO:0009966 regulation of signal transduction
1.89 7.19e-06 GO:0043009 chordate embryonic development
1.19 7.72e-06 GO:0044238 primary metabolic process
1.59 9.43e-06 GO:0032879 regulation of localization
1.66 1.25e-05 GO:0022008 neurogenesis
1.86 1.51e-05 GO:0009792 embryo development ending in birth or egg hatching
1.84 1.53e-05 GO:0010647 positive regulation of cell communication
1.58 1.56e-05 GO:0051641 cellular localization
1.75 1.59e-05 GO:0007154 cell communication
1.38 1.91e-05 GO:0048523 negative regulation of cellular process
1.42 2.47e-05 GO:0048513 organ development
1.63 2.51e-05 GO:0022607 cellular component assembly
1.62 2.99e-05 GO:0009888 tissue development
1.75 3.21e-05 GO:0007155 cell adhesion
1.81 4.30e-05 GO:0023056 positive regulation of signaling
1.63 4.48e-05 GO:0048468 cell development
1.74 5.04e-05 GO:0022610 biological adhesion
2.10 5.08e-05 GO:0001568 blood vessel development
1.18 5.43e-05 GO:0044237 cellular metabolic process
1.61 5.78e-05 GO:2000026 regulation of multicellular organismal development
1.61 5.81e-05 GO:0042592 homeostatic process
2.02 1.03e-04 GO:0001944 vasculature development
2.25 1.05e-04 GO:0051129 negative regulation of cellular component organization
1.64 1.25e-04 GO:0048699 generation of neurons
1.82 1.41e-04 GO:0009967 positive regulation of signal transduction
1.72 1.43e-04 GO:0048878 chemical homeostasis
1.36 1.49e-04 GO:0071842 cellular component organization at cellular level
1.50 1.50e-04 GO:0033036 macromolecule localization
1.85 2.75e-04 GO:0061024 membrane organization
1.10 2.82e-04 GO:0009987 cellular process
1.52 2.88e-04 GO:0051246 regulation of protein metabolic process
1.80 3.02e-04 GO:0032989 cellular component morphogenesis
2.02 3.04e-04 GO:0001701 in utero embryonic development
1.98 3.07e-04 GO:0031175 neuron projection development
1.52 3.37e-04 GO:0050793 regulation of developmental process
1.40 3.48e-04 GO:0006464 protein modification process
1.72 3.94e-04 GO:0001932 regulation of protein phosphorylation
2.16 3.96e-04 GO:0030029 actin filament-based process
2.24 4.18e-04 GO:0044087 regulation of cellular component biogenesis
1.84 4.74e-04 GO:0016044 cellular membrane organization
1.53 5.38e-04 GO:0032268 regulation of cellular protein metabolic process
1.82 6.19e-04 GO:0000902 cell morphogenesis
1.65 6.37e-04 GO:0019220 regulation of phosphate metabolic process
1.65 6.37e-04 GO:0051174 regulation of phosphorus metabolic process
1.67 6.50e-04 GO:0042325 regulation of phosphorylation
1.22 1.09e-03 GO:0019222 regulation of metabolic process
1.51 1.11e-03 GO:0008104 protein localization
1.37 1.30e-03 GO:0042221 response to chemical stimulus
1.91 1.54e-03 GO:0019226 transmission of nerve impulse
1.91 1.54e-03 GO:0035637 multicellular organismal signaling
1.32 1.58e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.56 1.85e-03 GO:0009790 embryo development
1.58 1.85e-03 GO:0051049 regulation of transport
1.73 1.86e-03 GO:0030030 cell projection organization
1.80 1.92e-03 GO:0009719 response to endogenous stimulus
2.11 2.35e-03 GO:0030036 actin cytoskeleton organization
1.69 2.40e-03 GO:0030182 neuron differentiation
1.49 2.42e-03 GO:0044085 cellular component biogenesis
1.83 2.54e-03 GO:0007610 behavior
1.92 2.56e-03 GO:0000904 cell morphogenesis involved in differentiation
1.79 2.56e-03 GO:0048666 neuron development
1.57 2.63e-03 GO:0031399 regulation of protein modification process
1.36 2.81e-03 GO:0043412 macromolecule modification
1.82 2.81e-03 GO:0090066 regulation of anatomical structure size
1.83 2.91e-03 GO:0051960 regulation of nervous system development
1.98 2.98e-03 GO:0045664 regulation of neuron differentiation
1.53 3.10e-03 GO:0051649 establishment of localization in cell
1.78 3.23e-03 GO:0007267 cell-cell signaling
1.54 3.62e-03 GO:0016310 phosphorylation
2.59 3.66e-03 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
2.01 3.76e-03 GO:0048812 neuron projection morphogenesis
1.95 4.78e-03 GO:0007507 heart development
1.60 4.78e-03 GO:0070887 cellular response to chemical stimulus
1.23 4.87e-03 GO:0031323 regulation of cellular metabolic process
1.78 5.14e-03 GO:0060284 regulation of cell development
1.67 5.35e-03 GO:0019725 cellular homeostasis
1.99 5.42e-03 GO:0061061 muscle structure development
2.01 6.07e-03 GO:0048514 blood vessel morphogenesis
3.05 6.65e-03 GO:0034330 cell junction organization
1.97 6.89e-03 GO:0010740 positive regulation of intracellular protein kinase cascade
1.80 7.63e-03 GO:0009725 response to hormone stimulus
1.38 7.91e-03 GO:0009893 positive regulation of metabolic process
2.14 8.49e-03 GO:0008015 blood circulation
1.22 9.73e-03 GO:0080090 regulation of primary metabolic process
2.13 9.76e-03 GO:0003013 circulatory system process
1.17 1.04e-02 GO:0043170 macromolecule metabolic process
1.83 1.11e-02 GO:0050767 regulation of neurogenesis
1.56 1.21e-02 GO:0006468 protein phosphorylation
1.78 1.47e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.75 1.71e-02 GO:0010627 regulation of intracellular protein kinase cascade
1.67 1.89e-02 GO:0050801 ion homeostasis
1.83 2.04e-02 GO:0032990 cell part morphogenesis
1.38 2.27e-02 GO:0031325 positive regulation of cellular metabolic process
1.83 2.33e-02 GO:0048858 cell projection morphogenesis
1.78 2.34e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.68 2.38e-02 GO:0055082 cellular chemical homeostasis
1.72 2.42e-02 GO:0044057 regulation of system process
1.69 2.66e-02 GO:0051247 positive regulation of protein metabolic process
2.36 2.75e-02 GO:0003012 muscle system process
1.94 2.86e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.72 3.36e-02 GO:0051093 negative regulation of developmental process
1.57 3.41e-02 GO:0040011 locomotion
1.68 3.42e-02 GO:0006873 cellular ion homeostasis
2.38 3.43e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.37 3.88e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.78 3.89e-02 GO:0035295 tube development
3.60 4.04e-02 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
2.43 4.46e-02 GO:0006936 muscle contraction
1.95 4.66e-02 GO:0006897 endocytosis
1.95 4.66e-02 GO:0010324 membrane invagination
1.95 4.66e-02 GO:0010562 positive regulation of phosphorus metabolic process
1.95 4.66e-02 GO:0045937 positive regulation of phosphate metabolic process
1.21 4.84e-02 GO:0060255 regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.41 3.03e-48 GO:0005737 cytoplasm
1.49 6.31e-38 GO:0044444 cytoplasmic part
1.26 6.55e-34 GO:0044424 intracellular part
1.25 1.00e-33 GO:0005622 intracellular
1.23 1.51e-19 GO:0043226 organelle
1.23 1.87e-19 GO:0043229 intracellular organelle
1.44 7.95e-18 GO:0071944 cell periphery
1.44 5.52e-17 GO:0005886 plasma membrane
1.11 2.73e-15 GO:0005623 cell
1.11 2.73e-15 GO:0044464 cell part
1.80 5.42e-15 GO:0000267 cell fraction
1.61 3.80e-14 GO:0044459 plasma membrane part
1.77 1.23e-12 GO:0042995 cell projection
2.05 1.25e-12 GO:0030054 cell junction
1.21 2.41e-12 GO:0043227 membrane-bounded organelle
1.21 2.75e-12 GO:0043231 intracellular membrane-bounded organelle
1.75 6.24e-10 GO:0005626 insoluble fraction
1.73 8.12e-09 GO:0005624 membrane fraction
2.00 1.56e-08 GO:0045202 synapse
1.67 4.17e-08 GO:0044421 extracellular region part
1.75 5.63e-08 GO:0031982 vesicle
2.28 9.38e-08 GO:0015629 actin cytoskeleton
1.45 1.50e-07 GO:0005576 extracellular region
1.64 2.47e-07 GO:0005794 Golgi apparatus
1.87 2.51e-07 GO:0031988 membrane-bounded vesicle
1.75 2.52e-07 GO:0031410 cytoplasmic vesicle
1.50 2.79e-07 GO:0005856 cytoskeleton
1.69 6.08e-07 GO:0012505 endomembrane system
1.82 7.31e-07 GO:0043005 neuron projection
1.72 7.78e-07 GO:0005615 extracellular space
1.58 1.01e-06 GO:0005783 endoplasmic reticulum
1.86 1.29e-06 GO:0016023 cytoplasmic membrane-bounded vesicle
1.15 5.28e-06 GO:0016020 membrane
2.00 5.67e-06 GO:0005625 soluble fraction
2.02 8.05e-06 GO:0044456 synapse part
1.44 1.45e-05 GO:0005829 cytosol
1.49 1.55e-05 GO:0031090 organelle membrane
1.24 1.59e-05 GO:0044422 organelle part
1.30 2.37e-05 GO:0043234 protein complex
1.27 2.89e-05 GO:0032991 macromolecular complex
2.05 3.31e-05 GO:0044431 Golgi apparatus part
1.23 3.78e-05 GO:0044446 intracellular organelle part
2.04 4.77e-05 GO:0030425 dendrite
2.30 1.71e-04 GO:0031252 cell leading edge
2.95 2.14e-04 GO:0030027 lamellipodium
1.90 3.09e-04 GO:0043025 neuronal cell body
1.87 3.66e-04 GO:0044297 cell body
2.09 4.99e-04 GO:0016323 basolateral plasma membrane
1.94 5.29e-04 GO:0005578 proteinaceous extracellular matrix
2.29 5.46e-04 GO:0044433 cytoplasmic vesicle part
1.86 7.45e-04 GO:0031012 extracellular matrix
2.23 1.88e-03 GO:0030659 cytoplasmic vesicle membrane
2.78 1.88e-03 GO:0014069 postsynaptic density
1.97 3.24e-03 GO:0005911 cell-cell junction
1.26 3.91e-03 GO:0043228 non-membrane-bounded organelle
1.26 3.91e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.82 5.10e-03 GO:0048471 perinuclear region of cytoplasm
1.44 6.30e-03 GO:0044430 cytoskeletal part
1.88 6.95e-03 GO:0045177 apical part of cell
2.08 7.09e-03 GO:0012506 vesicle membrane
2.50 8.04e-03 GO:0016327 apicolateral plasma membrane
6.37 1.02e-02 GO:0060076 excitatory synapse
2.25 1.03e-02 GO:0005912 adherens junction
2.50 1.19e-02 GO:0030017 sarcomere
2.39 1.33e-02 GO:0044449 contractile fiber part
2.67 1.45e-02 GO:0044309 neuron spine
2.45 1.73e-02 GO:0043296 apical junction complex
1.92 1.91e-02 GO:0030141 stored secretory granule
2.25 2.81e-02 GO:0044445 cytosolic part
2.14 2.88e-02 GO:0019717 synaptosome
2.04 3.13e-02 GO:0000139 Golgi membrane
2.61 3.25e-02 GO:0043197 dendritic spine
2.23 3.28e-02 GO:0044420 extracellular matrix part
2.18 3.49e-02 GO:0043292 contractile fiber
1.99 4.05e-02 GO:0030135 coated vesicle
2.33 4.09e-02 GO:0008021 synaptic vesicle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.49 6.77e-38 GO:0005515 protein binding
1.24 5.38e-28 GO:0005488 binding
2.23 9.89e-14 GO:0008092 cytoskeletal protein binding
2.64 2.79e-13 GO:0003779 actin binding
1.65 5.57e-08 GO:0005102 receptor binding
1.82 1.01e-05 GO:0005509 calcium ion binding
1.75 6.42e-05 GO:0019904 protein domain specific binding
1.60 7.88e-05 GO:0042802 identical protein binding
1.56 1.73e-04 GO:0019899 enzyme binding
1.82 3.22e-04 GO:0008289 lipid binding
1.75 6.43e-03 GO:0032403 protein complex binding
1.80 1.09e-02 GO:0019900 kinase binding
1.88 1.36e-02 GO:0019901 protein kinase binding
2.04 1.64e-02 GO:0005543 phospholipid binding
1.69 1.91e-02 GO:0030246 carbohydrate binding